Mcl1-IN-1_713492-66-1_DataSheet_MedChemExpress
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Product Name:
Mcl1-IN-1CAS No.:
713492-66-1Cat. No.:
HY-16669MWt:
435.86Formula:
C23H18ClN3O4Purity :>98%
Solubility:Mechanisms:
Biological Activity:
References:
Caution: Not fully tested. For research purposes only
Medchemexpress LLC
[1]. Richard DJ, et al. Hydroxyquinoline-derived compounds and analoguing of selective Mcl-1 inhibitors
using a functional biomarker. Bioorg Med Chem. 2013 Nov 1;21(21):6642-9.Mcl1-IN-1 is a potent Mcl-1-selective inhibitor relative to the related Bcl-2 family protein Bcl-xL;
demonstrated good Mcl-1 inhibition (IC50 = 2.4 uM) with no appreciable inhibition of Bcl-xL at 100 uM.
IC50 value: 2.4 uM Target: Mcl-1
Pathways:Apoptosis; Target:Bcl-2 Family Product Data Sheet
DMSO > 50 mg/ml
11D e e r P a r kD r i v e S u i t e 102D M o n m o u t h J u n c t i o n , N J 08852,U S A
E m a i l : i n f o @m e d c h e m e x p r e s s .c o m W e b : w w w .m e d c h e m e x p r e s s .c o m