羟苯磺酸钙联合降糖药治疗糖尿病视网膜病变伴白内障的临床效果

控制血糖袁改善视力袁且用药安全遥
[关键词] 糖尿病视网膜病变曰白内障曰羟苯磺酸钙曰血糖曰血液流变学
[中图分类号] R779.6
[文献标识码] A
[文章编号] 1673-7210渊2019冤09渊b冤-0152-05
Clinical effect of Calcium Dobesilate combined with hypoglycemic agents
in the treatment of diabetic retinopathy with cataract
GUO Jing1 GUO Jing2 CHEN He2
1.Ophthalmology Department, Yingkou Central Hospital, Liaoning Province, Yingkou 115002, China; 2.Endocrine
渊HbA1c冤水平均较治疗前降低渊P 约 0.05冤遥两组治疗后红细胞变形指数尧血浆黏度尧红细胞聚集指数尧血细胞比容及
血清 VEGF尧HIF-1琢 水平均较治疗前降低渊P 约 0.05冤袁且观察组上述指标均低于对照组渊P 约 0.05冤遥 两组治疗期间
未发现明显不良反应遥 结论 常规降糖药联合羟苯磺酸钙治疗糖尿病视网膜病变伴白内障患者效果显著袁可有效
treatment of diabetic retinopathy with cataract. Methods A total of 86 diabetic retinopathy patients (118 eyes) with
cataract admitted to Yingkou Central Hospital of Liaoning Province from January 2016 to May 2018 were selected and
The total effective rate of the clinical efficacy of the observation group was higher than that of the control group, and
the difference was statistically significant (P 约 0.05). After treatment, the naked vision of both groups was increased
窑 药物与临床 窑
中国医药导报 2019 年 9 月第 16 卷第 26 期
羟苯磺酸钙联合降糖药治疗糖尿病视网膜病变 伴白内障的临床效果
郭 静1 郭 靖2 陈 贺2 1.辽宁省营口市中心医院眼科袁辽宁营口 115002曰2.辽宁省营口市中心医院内分泌科袁辽宁营口 115002
[摘要] 目的 探讨羟苯磺酸钙联合降糖药治疗糖尿病视网膜病变伴白内障的临床效果遥 方法 选取 2016 年
1 月耀2018 年 5 月辽宁省营口市中心医院收治的糖尿病视网膜病变伴白内障患者 86 例渊118 眼冤袁按随机数字表
法将其分为对照组渊43 例袁60 眼冤和观察组渊43 例袁58 眼冤遥 对照组给予常规降糖药治疗袁观察组在常规降糖药的
基础上联合羟苯磺酸钙治疗遥 治疗 3 个月后袁比较两组临床疗效及用药不良反应袁观察两组治疗前后裸眼视力情
treated with Calcium Dobesilate on the basis of routine hypoglycemic agents. After 3 months of treatment, the clinical
efficacy and adverse drug reactions of the two groups were compared. The naked vision of the two groups before and af鄄
况袁检测并比较两组血糖指标尧血液流变学指标及血管内皮生长因子渊VEGF冤尧缺氧诱导因子渊HIF-1琢冤水平变
化遥 结果 观察组临床疗效的总有效率高于对照组袁差异有统计学意义渊P 约 0.05冤遥 两组治疗后裸眼视力均较治
疗前升高袁且观察组高于对照组渊P 约 0.05冤BG冤及糖化血红蛋白
divided into the control group (43 cases, 60 eyes) and the observation group (43 cases, 58 eyes) according to random
number table method. The control group was treated with routine hypoglycemic agents, while the observation group was
ter treatment was observed, and the blood glucose indexes, hemorheology indexes, the levels of vascular endothelial
growth factor (VEGF) and hypoxia-inducible factor (HIF-1琢) were detected and compared in the two groups. Results
compared with that before treatment, and the observation group was higher than the control group (P 约 0.05). After
Department, Yingkou Central Hospital, Liaoning Province, Yingkou 115002, China
[Abstract] Objective To explore the clinical efficacy of Calcium Dobesilate combined with hypoglycemic agents in the