OXIDATION OF STEROIDS HAVING ALLYLIC GROUPS

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专利名称:OXIDATION OF STEROIDS HAVING ALLYLIC GROUPS

发明人:MILLER, ROSS, A.,THOMPSON, ANDREW, S.,BAKSHI, RAMAN, K.,CORLEY, EDWARD, G.申请号:EP95920434

申请日:19950515

公开号:EP0759929A4

公开日:

19980930

专利内容由知识产权出版社提供

摘要:The instant invention involves a process for oxidizing compounds containing an allylic group, i.e. those containing an allylic hydrogen or allylic alcohol group, to the corresponding enones, using a ruthenium-based catalyst in the presence of a hydroperoxide. Particularly, Δ-5-steriodal alkenes can be oxidized to the corresponding Δ-5-7-keto alkenes.

申请人:MERCK & CO., INC. (A NEW JERSEY CORP.)

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