ISOLATION AND CHARACTERIZATION OF A NOVEL PRIMATE
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专利名称:ISOLATION AND CHARACTERIZATION OF A NOVEL PRIMATE T-CELL LYMPHOTROPIC
VIRUS AND THE USE OF THIS VIRUS OR
COMPONENTS THEREOF IN DIAGNOSTICS
ASSAYS AND VACCINES
发明人:FRANCHINI, Genoveffa,GALLO, Robert,
C.,MARKHAM, Phillip,GIRI, Adriana
申请号:US1995004910
申请日:19950421
公开号:WO95/029240P1
公开日:
19951102
专利内容由知识产权出版社提供
摘要:The isolation and characterization of a novel primate T-cell lymphotropic virus designated STLVpan-p is disclosed. The invention relates to the proviral DNA of this virus and to the use of the nucleic acid sequence encoded by this proviral DNA to design nucleic acid probes and synthesize proteins which may be used in diagnostic and vaccines. Antibodies to these proteins or to the viral particle itself are also disclosed where such antibodies may be useful in immunoassays for detecting STLVpan-p viral antigens in individuals and where such antibodies may be used for treatment of STLVpan-p viral infections in individuals. The reagents provided in this invention also enable isolation of related T-cell lymphotropic viruses in other species. Finally, the present invention discloses the propagation of these viruses in tissue culture systems where such systems are useful for screening for anti-viral agents for STLVpan-p viruses.
申请人:FRANCHINI, Genoveffa,GALLO, Robert, C.,MARKHAM, Phillip,GIRI, Adriana
地址:US,US,US,US,US
国籍:US,US,US,US,US
代理机构:FEILER, William, S.更多信息请下载全文后查看。