重症监护室重型颅脑损伤致肺部感染的临床用药分析

重症监护室重型颅脑损伤致肺部感染的临床用药分析
罗志建
【期刊名称】《蚌埠医学院学报》
【年(卷),期】2015(40)8
【摘要】Objective:To investigate the clinical condition of pulmonary infection caused by severe head trauma infensive care unit, and observe its clinical manifestations and drug effects. Methods:The clinical diagnosis and treatment data of 110 cases with pulmonary infection caused by severe head trauma were retrospectively analyzed. Results:The incidence of pulmonary infection caused by severe head trauma was high. Eighty-eight strains of gram-negative bacteria(73. 3%),26 strains of gram-positive bacteria(21. 7%) and 6 strains of fungi (5. 0%) were found. The sensitivities of imipenem and vancomycin were the highest. All patients were alleviated after treatment. Conclusions:The gram-negative bacteria in pulmonary infection caused by severe head trauma infensive care unit is the major pathogenic bacteria. The patient is multiple drug resistance,the use of antibiotics should be strictly control.%目的：：了解重症监护室( ICU)重型颅脑损伤致肺部感染的发生情况、临床表现及用药效果。

方法：对110例ICU重型颅脑损伤出现肺部感染患者的临床诊治资料进行回顾性分析。

结果：ICU重型颅脑损伤出现肺部感染的发生率较高，病原菌中革兰阴性菌88株，占73.3％，革兰阳性菌26株，占21.7％，真菌6株，占5.0％。

革兰阴性菌和阳性菌分别以铜绿假单胞杆菌和金黄色葡萄球菌检出率最高，分别对头胞哌酮和万古霉素的敏感率最高。

经治疗，所有病例均得到缓解。

结论：ICU重型颅脑损伤致肺部感染的致病菌以革兰阴性菌为主，且多重耐药情况严重，须严格控制抗生素的使用。

【总页数】3页(P1020-1022)
【作者】罗志建
【作者单位】四川省仁寿县人民医院呼吸内科，620500
【正文语种】中文
【中图分类】R651.1
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