盐碘标准调整后淮安市重点人群尿碘变化分析
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盐碘标准调整后淮安市重点人群尿碘变化分析
摘要：目的动态了解淮安市8-10岁学龄儿童、育龄妇女、孕妇碘营养状况及2012年盐碘含量标准调整后碘营养变化。方法从2009年起连续对淮安市6县（区）的学龄儿童、育龄妇女、孕妇抽样监测，检测尿样以了解其碘营养状况，同时监测居民户盐碘含量。结果2009-2014年碘盐合格率及合格碘盐食用率均在98%以上。2009-2012年各年度盐碘均值均>30mg/kg，盐碘含量调整后2013-2014年度盐碘均值明显降低，分别为25.8mg/kg、25.2mg/kg，差异有统计学意义（P＜0.01）。2009-2014年共检测2528份学龄儿童、2329份育龄妇女、1413份孕妇的尿样。学龄儿童及育龄妇女2009-2011年尿碘中位数全部＞200μg/L，超过适宜量；2012-2014年的明显降低，全部在100-200μg/L的适宜范围内，差异有统计学意义（P＜0.01）。2009-2014年孕妇尿碘中位数全部在150-250μg/L的适宜范围内。2012-2014年学龄儿童及育龄妇女100-199μg/L及100-299μg/L的样品比例大于2009-2011年，≥300μg/L样品比例小于2009-2011年，差异有统计学意义（P＜0.01）。2009-2011年孕妇≥500μg/L+样品比例大于2012-2014年，差异有统计学意义（P＜0.01）。结论碘盐含量标准调整后，淮安市居民碘盐含量明显降低，8-10岁学龄儿童、育龄妇女的尿碘中位数降低至适tract】Objective To investigate dynamically the status of iodine nutrition of school-age children，fertile women and pregnant women in Huaian city and the variation of iodine nutrition after adjustment of iodized salt standard from 2012.Methods From 2009，we continuously monitored the school-age children，fertile women and pregnant women in 6 counties and districts Huaian.The urine iodine was detected to understand their iodine nutrition status while iodine content of household iodized salt was monitored at the same time.Results From 2009 to 2014，the qualified rates of iodized salt and household usage rates of adequately iodized salt were all more than 98%.The mean of salt iodine were all more than 30mg/kg from 2009 to 2012.The mean of salt iodine reduced in 2013-2014 after adjustment of iodized salt standard，they were 25.8mg/kg and 25.2mg/kg respectively.The difference was statistically significant（P<0.01）.From 2009 to 2014 we detected 2528 urinary iodine samples from school-age children，2329 urinary iodine samples from fertile women and 1413 urinary iodine samples from pregnant women total.The urinary iodine median of school-age children and fertile women in 2009-2011 were all more than 200μg/L，more than the fitting range.The urinary iodine median in 2012-2014 were reduced，they were all between 100-200μg/L，in the fitting range.The difference was statistically significant（P<0.01）.In 2009-2014 the urinary iodine median of pregnant women were all between 150-250μg/L，in the fitting range.In 2012-2014 the ratios of school-age children and fertile women samples with urinary iodine levels 100-199.9μg/L and 100-299.9μg/L were all more than 2009-2011，the ratios of samples with urinary iodine levels >300μg/L were all less than 2009-2011.The difference was statistically significant（P<0.01）.In 2009-2011 the ratios of pregnant women samples with urinary iodine levels ≥500μg/L were all more than 2012-2014.The difference was statistically significant（P<0.01）.Conclusion After adjustment of iodized salt standard，the mean of salt iodine declined and urinary iodine median of key population was down to the fitting range in Huaian city.
摘要：目的动态了解淮安市8-10岁学龄儿童、育龄妇女、孕妇碘营养状况及2012年盐碘含量标准调整后碘营养变化。方法从2009年起连续对淮安市6县（区）的学龄儿童、育龄妇女、孕妇抽样监测，检测尿样以了解其碘营养状况，同时监测居民户盐碘含量。结果2009-2014年碘盐合格率及合格碘盐食用率均在98%以上。2009-2012年各年度盐碘均值均>30mg/kg，盐碘含量调整后2013-2014年度盐碘均值明显降低，分别为25.8mg/kg、25.2mg/kg，差异有统计学意义（P＜0.01）。2009-2014年共检测2528份学龄儿童、2329份育龄妇女、1413份孕妇的尿样。学龄儿童及育龄妇女2009-2011年尿碘中位数全部＞200μg/L，超过适宜量；2012-2014年的明显降低，全部在100-200μg/L的适宜范围内，差异有统计学意义（P＜0.01）。2009-2014年孕妇尿碘中位数全部在150-250μg/L的适宜范围内。2012-2014年学龄儿童及育龄妇女100-199μg/L及100-299μg/L的样品比例大于2009-2011年，≥300μg/L样品比例小于2009-2011年，差异有统计学意义（P＜0.01）。2009-2011年孕妇≥500μg/L+样品比例大于2012-2014年，差异有统计学意义（P＜0.01）。结论碘盐含量标准调整后，淮安市居民碘盐含量明显降低，8-10岁学龄儿童、育龄妇女的尿碘中位数降低至适tract】Objective To investigate dynamically the status of iodine nutrition of school-age children，fertile women and pregnant women in Huaian city and the variation of iodine nutrition after adjustment of iodized salt standard from 2012.Methods From 2009，we continuously monitored the school-age children，fertile women and pregnant women in 6 counties and districts Huaian.The urine iodine was detected to understand their iodine nutrition status while iodine content of household iodized salt was monitored at the same time.Results From 2009 to 2014，the qualified rates of iodized salt and household usage rates of adequately iodized salt were all more than 98%.The mean of salt iodine were all more than 30mg/kg from 2009 to 2012.The mean of salt iodine reduced in 2013-2014 after adjustment of iodized salt standard，they were 25.8mg/kg and 25.2mg/kg respectively.The difference was statistically significant（P<0.01）.From 2009 to 2014 we detected 2528 urinary iodine samples from school-age children，2329 urinary iodine samples from fertile women and 1413 urinary iodine samples from pregnant women total.The urinary iodine median of school-age children and fertile women in 2009-2011 were all more than 200μg/L，more than the fitting range.The urinary iodine median in 2012-2014 were reduced，they were all between 100-200μg/L，in the fitting range.The difference was statistically significant（P<0.01）.In 2009-2014 the urinary iodine median of pregnant women were all between 150-250μg/L，in the fitting range.In 2012-2014 the ratios of school-age children and fertile women samples with urinary iodine levels 100-199.9μg/L and 100-299.9μg/L were all more than 2009-2011，the ratios of samples with urinary iodine levels >300μg/L were all less than 2009-2011.The difference was statistically significant（P<0.01）.In 2009-2011 the ratios of pregnant women samples with urinary iodine levels ≥500μg/L were all more than 2012-2014.The difference was statistically significant（P<0.01）.Conclusion After adjustment of iodized salt standard，the mean of salt iodine declined and urinary iodine median of key population was down to the fitting range in Huaian city.