IMPROVED ANTIBODY PROFILING SENSITIVITY THROUGH I

专利名称：IMPROVED ANTIBODY PROFILING SENSITIVITY THROUGH INCREASED

REPORTER ANTIBODY LAYERING 发明人：APEL, William A.,THOMPSON, Vicki S.申请号：US2008054011

申请日：20080214

公开号：WO08/118558P1

公开日：

20081002

专利内容由知识产权出版社提供

摘要：A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an embodiment of the invention, the analyte is a drug, such as marijuana, cocaine, methamphetamine, methyltestosterone, or mesterolone. The method comprises attaching antigens to the surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array to form immune complexes; washing away antibodies that do form immune complexes; and detecting the immune complexes, to form an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to the subject's identity.

申请人：BATTELLE ENERGY ALLIANCE, LLC

地址：US

国籍：US

代理机构：BARZEE, Eric M.更多信息请下载全文后查看