多模式神经电生理检测对脊髓手术患者神经功能状态的评估分析及其
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【Key words】 spinal cord surgery; electromyography; somatosensory evoked potential; motor ev们的生活方 式及饮食习惯的改变,脊髓病变的发病率逐年递增, 而随着外科手术技术的发展,更多高难度的脊髓疾 病需要 接 受 手 术 治 疗[1]。因 此,增 加 手 术 的 安 全 性,避免术中及术后神经损伤的发生是临床亟需解 决的重要问题。肌电图[2]( electromyography,EMG) 是神经功能检测的重要手段,主要检查相应神经根 支配的肌肉,体感诱发电位[3]( somatosensory evoked
756
武警医学 2019 年 9 月 第 30 卷 第 9 期 Med J Chin PAP,Vol. 30,No. 9,September,2019
多模式神经电生理检测对脊髓手术患者神经功能状态的 评估分析及其影响因素
沈 强1 ,朱 玲2 ,白 雪2 ,于绍斌2 ,刘凤欣2
【摘要】 目的 使用肌电图( electromyography,EMG) 、体感诱发电位( somatosensory evoked potential,SEP) 与运动诱发电 位( motor evoked potentials,MEP) 多模式方法检测手术前后神经系统的多种电生理信号,探讨患者神经功能状态。方法 收集 100 例患者作为研究对象,术中监测患者双下肢的 SEP 与 MEP 情况; 术后 6 个月复查患者 EMG。结果 术中 SEP 波幅与潜伏 期在较稳定情况下,MEP 监测中 42 例患者术中的 D 波波幅发生降低未超过 50% ,22 例患者出现 D 波波幅突然下降且超过 50% 。Pearson 相关性分析结果表明,术中出血量与 SEP 及 MEP 波幅与潜伏期的改变具有相关性。术后复查,各组患者的腓 总神经与胫神经的 NCV 与 DL 均有显著改善,异常组患者的改善情况明显低于其他四组。结论 使用 EMG、SEP 与 MEP 多模 式神经电生理检测可以去除干扰因素,为脊髓手术提供客观、有价值的诊疗依据。
【Abstract】 Objective To investigate the various electrophysiological signals of the nervous system before and after operation using EMG,SEP and MEP multimode methods,and to explore the neurofunctional status of patients. Methods One hundred patients were collected as subjects,and the SEP and MEP of patients with bilateral lower limbs were monitored. EMG was resumed 6 months after surgery. Results The SEP amplitude and latent period were stable during the operation. In the process of MEP monitoring,the amplitude of D wave was decreased by less than than 50% in 42 patients,but suddenly decreased by more than 50% in 22 patients. Pearson correlation analysis showed that intraoperative blood loss was associated with changes in SEP and MEP amplitude and latency. The postoperative re-examination found that the NCV and DL of the peroneal nerve and tibial nerve in each group were significantly improved,but the abnormal group improved much less significantly than in the other four groups. Conclusions EMG,SEP and MEP multimode neuroelectrophy-siological detection can remove interference and provide objective and valuable data for diagnosis and treatment of spinal cord surgery.
【关键词】 脊髓手术; 肌电图; 体感诱发电位; 运动诱发电位 【中国图书分类号】 R744
Evaluation of neurologic function and influencing factors in patients with spinal cord surgery
SHEN Qiang1 ,ZHU Ling2 ,BAI Xue2 ,YU Shaobin2 ,and LIU Fengxin2 . 1. Hebei Provincial Corps Hospital of Chinese People’s Armed Police Force,Shijiazhuang 050081,China; 2. Department of Electromyography,The third hospital of hebei medical university, Shijiazhuang 050000,China
756
武警医学 2019 年 9 月 第 30 卷 第 9 期 Med J Chin PAP,Vol. 30,No. 9,September,2019
多模式神经电生理检测对脊髓手术患者神经功能状态的 评估分析及其影响因素
沈 强1 ,朱 玲2 ,白 雪2 ,于绍斌2 ,刘凤欣2
【摘要】 目的 使用肌电图( electromyography,EMG) 、体感诱发电位( somatosensory evoked potential,SEP) 与运动诱发电 位( motor evoked potentials,MEP) 多模式方法检测手术前后神经系统的多种电生理信号,探讨患者神经功能状态。方法 收集 100 例患者作为研究对象,术中监测患者双下肢的 SEP 与 MEP 情况; 术后 6 个月复查患者 EMG。结果 术中 SEP 波幅与潜伏 期在较稳定情况下,MEP 监测中 42 例患者术中的 D 波波幅发生降低未超过 50% ,22 例患者出现 D 波波幅突然下降且超过 50% 。Pearson 相关性分析结果表明,术中出血量与 SEP 及 MEP 波幅与潜伏期的改变具有相关性。术后复查,各组患者的腓 总神经与胫神经的 NCV 与 DL 均有显著改善,异常组患者的改善情况明显低于其他四组。结论 使用 EMG、SEP 与 MEP 多模 式神经电生理检测可以去除干扰因素,为脊髓手术提供客观、有价值的诊疗依据。
【Abstract】 Objective To investigate the various electrophysiological signals of the nervous system before and after operation using EMG,SEP and MEP multimode methods,and to explore the neurofunctional status of patients. Methods One hundred patients were collected as subjects,and the SEP and MEP of patients with bilateral lower limbs were monitored. EMG was resumed 6 months after surgery. Results The SEP amplitude and latent period were stable during the operation. In the process of MEP monitoring,the amplitude of D wave was decreased by less than than 50% in 42 patients,but suddenly decreased by more than 50% in 22 patients. Pearson correlation analysis showed that intraoperative blood loss was associated with changes in SEP and MEP amplitude and latency. The postoperative re-examination found that the NCV and DL of the peroneal nerve and tibial nerve in each group were significantly improved,but the abnormal group improved much less significantly than in the other four groups. Conclusions EMG,SEP and MEP multimode neuroelectrophy-siological detection can remove interference and provide objective and valuable data for diagnosis and treatment of spinal cord surgery.
【关键词】 脊髓手术; 肌电图; 体感诱发电位; 运动诱发电位 【中国图书分类号】 R744
Evaluation of neurologic function and influencing factors in patients with spinal cord surgery
SHEN Qiang1 ,ZHU Ling2 ,BAI Xue2 ,YU Shaobin2 ,and LIU Fengxin2 . 1. Hebei Provincial Corps Hospital of Chinese People’s Armed Police Force,Shijiazhuang 050081,China; 2. Department of Electromyography,The third hospital of hebei medical university, Shijiazhuang 050000,China