Motolimod_COA_20000_MedChemExpress
用于CO_(2)分离的含氨基酸盐促进传递膜研究进展
用于CO_(2)分离的含氨基酸盐促进传递膜研究进展
马玉磊;魏静;银登国;冯超;杜文韬;黄娅;代忠德
【期刊名称】《膜科学与技术》
【年(卷),期】2024(44)2
【摘要】膜分离法由于其高度模块化、占地面积小、化学排放低或无化学排放和易于操作等优势,被广泛认为是有前途的CO_(2)分离技术.然而,对于气体分离,大多数聚合物膜遵循溶解-扩散机制,因此需要在气体渗透性和选择性之间进行权衡,使CO_(2)分离膜在工业应用中受到限制.而促进传递膜被认为是克服这一限制的有效解决方案.本文综述了用于CO_(2)捕集的含氨基酸盐促进传递膜的研究进展,并针对目前存在的问题,对未来含氨基酸盐的促进传递膜的发展方向提出了建议.
【总页数】12页(P165-176)
【作者】马玉磊;魏静;银登国;冯超;杜文韬;黄娅;代忠德
【作者单位】四川大学建筑与环境学院;国家烟气脱硫工程技术研究中心;四川省碳中和技术创新中心;四川大学碳中和未来技术学院;东方电气集团东方锅炉股份有限公司;成都信息工程大学资源与环境学院
【正文语种】中文
【中图分类】TQ028;TQ31
【相关文献】
1.基于促进传递机理的一氧化碳分离膜研究进展
2.氨基酸离子液体/Pebax膜的制备及CO_(2)分离测试
3.陶瓷碳酸盐双相膜分离CO_(2)的研究进展
4.沸石膜在分
离烟气中CO_(2)的挑战:沸石与载体间结合力研究进展5.UiO-66-NH_(2)/聚醚酰亚胺中空纤维膜的制备及其用于CO_(2)分离的研究
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Motolimod_SDS_MedChemExpress
Inhibitors, Agonists, Screening LibrariesSafety Data Sheet Revision Date:May-24-2017Print Date:May-24-20171. PRODUCT AND COMPANY IDENTIFICATION1.1 Product identifierProduct name :MotolimodCatalog No. :HY-13773CAS No. :926927-61-91.2 Relevant identified uses of the substance or mixture and uses advised againstIdentified uses :Laboratory chemicals, manufacture of substances.1.3 Details of the supplier of the safety data sheetCompany:MedChemExpress USATel:609-228-6898Fax:609-228-5909E-mail:sales@1.4 Emergency telephone numberEmergency Phone #:609-228-68982. HAZARDS IDENTIFICATION2.1 Classification of the substance or mixtureNot a hazardous substance or mixture.2.2 GHS Label elements, including precautionary statementsNot a hazardous substance or mixture.2.3 Other hazardsNone.3. COMPOSITION/INFORMATION ON INGREDIENTS3.1 SubstancesSynonyms:VTX⁻2337; VTX⁻378Formula:C28H34N4O2Molecular Weight:458.60CAS No. :926927-61-94. 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《具有多酶模拟活性的氧化钒纳米酶的抗肿瘤作用研究》
《具有多酶模拟活性的氧化钒纳米酶的抗肿瘤作用研究》摘要：本文研究了一种具有多酶模拟活性的氧化钒纳米酶（VOx Nanoenzyme）在抗肿瘤领域的应用。
通过合成具有特定形貌和尺寸的氧化钒纳米粒子，并对其酶学活性进行评估，探讨了其在肿瘤细胞内的作用机制及抗肿瘤效果。
研究结果表明，该纳米酶能够有效抑制肿瘤细胞的生长，并有望成为一种新型的抗肿瘤治疗方法。
一、引言肿瘤作为一种严重的全球性健康问题，一直是医学领域的研究重点。
随着纳米医学和生物技术的发展，越来越多的纳米材料被用于抗肿瘤研究。
其中，纳米酶因其具有良好的生物相容性和酶学活性而备受关注。
氧化钒纳米酶作为其中一种典型的代表，因其独特的物理化学性质和多酶模拟活性，在抗肿瘤领域展现出巨大的应用潜力。
二、材料与方法1. 合成方法：采用水热法或溶胶凝胶法合成具有特定形貌和尺寸的氧化钒纳米粒子。
通过调节反应条件，控制粒子的尺寸和形貌。
2. 酶学活性评估：通过体外实验，测定纳米酶的类过氧化物酶、类超氧化物歧化酶、类谷胱甘肽过氧化物酶等活性，以评估其多酶模拟活性。
3. 细胞实验：将合成的氧化钒纳米酶与肿瘤细胞共培养，观察其对肿瘤细胞生长的抑制作用，并探讨其作用机制。
三、结果与讨论1. 合成与表征：成功合成了具有特定形貌和尺寸的氧化钒纳米粒子，并通过透射电子显微镜（TEM）和X射线衍射（XRD）等技术对其进行了表征。
2. 酶学活性评估：实验结果显示，氧化钒纳米酶具有类过氧化物酶、类超氧化物歧化酶、类谷胱甘肽过氧化物酶等活性，其多酶模拟活性有利于在生物体内发挥多种生物学效应。
3. 抗肿瘤作用机制：将氧化钒纳米酶与肿瘤细胞共培养后发现，纳米酶能够有效地抑制肿瘤细胞的生长，并诱导其凋亡。
进一步研究发现，纳米酶通过产生反应性氧物种（ROS）等途径，破坏肿瘤细胞的代谢平衡，从而达到抑制肿瘤细胞生长的目的。
此外，纳米酶还能够影响肿瘤细胞的信号传导途径，如NF-κB等，从而发挥抗肿瘤作用。
《具有多酶模拟活性的氧化钒纳米酶的抗肿瘤作用研究》
《具有多酶模拟活性的氧化钒纳米酶的抗肿瘤作用研究》摘要：本文研究了具有多酶模拟活性的氧化钒纳米酶（Vanadium Oxide Nanozyme，VON）在抗肿瘤领域的应用。
通过实验证明，VON能够有效模拟多种酶的活性，并在肿瘤治疗中发挥重要作用。
本文首先概述了纳米酶的研究现状与抗肿瘤的重要性，接着详细介绍了VON的制备方法、结构特征、多酶模拟活性以及在抗肿瘤过程中的作用机制，最后通过实验数据和结果分析，验证了VON在抗肿瘤治疗中的有效性及安全性。
一、引言近年来，纳米科技在生物医学领域的应用日益广泛，其中纳米酶因其独特的催化性能和生物相容性而备受关注。
氧化钒纳米酶（VON）作为一种新型的纳米酶，因其具有多酶模拟活性，在抗肿瘤治疗中展现出巨大的应用潜力。
本文旨在研究VON的制备、结构特征、多酶模拟活性以及其在抗肿瘤作用中的机制。
二、材料与方法1. 材料实验所用的VON通过溶胶-凝胶法结合热处理工艺制备，所用试剂均为分析纯。
细胞系选用人源肿瘤细胞株及正常细胞株。
2. 方法（1）VON的制备与表征：通过透射电子显微镜（TEM）、X射线衍射（XRD）等技术对VON的形貌、结构及成分进行表征。
（2）多酶模拟活性检测：通过酶活性检测试剂盒，检测VON对多种酶的模拟活性。
（3）细胞实验：采用MTT法检测VON对肿瘤细胞的增殖抑制作用，流式细胞术检测细胞凋亡及周期变化。
（4）动物实验：建立肿瘤小鼠模型，评估VON的抗肿瘤效果及生物安全性。
三、结果与分析1. VON的制备与表征透射电子显微镜观察显示，VON呈均匀的球形或类球形纳米颗粒，粒径分布较为集中。
XRD分析表明，VON具有典型的氧化钒结构。
2. 多酶模拟活性检测实验结果显示，VON具有过氧化物酶、超氧化物歧化酶等多种酶的模拟活性，能够在一定程度上替代这些酶的生物功能。
3. 细胞实验结果MTT法检测结果显示，VON能够显著抑制肿瘤细胞的增殖，而对正常细胞的生长影响较小。