11 introduction 1

As one of the most common detrimental occupational diseases, silicosis has directly and indirectly caused more than nine billion RMB (financial) losses in China.1,2 There is also a new trend of higher rate of disability among the population exposed to silica dust (even) for a short time, posing a challenge to the prevention and control of this disease. Under such condition, early period of intervention may do good to slow the progress of silicosis. Till now, the pathogenesis of silicosis is not clear yet and there are no specific targets for early diagnosis or treatment.
在非常糟糕的天气条件下很容易在这里拐错弯
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Silicosis (矽肺病), a kind of systematic disease caused by the inhalation of silica dust, characterized mainly by pulmonary (肺部的） interstitial （ 组织间隙的）fibrosis （纤维化）. It is one of the most common detrimental occupational diseases and caused more than nine billion RMB economy losses directly and indirectly in China.1,2 There existed a new trend with higher disability in population of short period silica exposure, and this phenomenon posed challenge to prevent and manage of this disease. Till now, the pathogenesis of silicosis is not clear yet and there are no specific targets for early diagnosis or treatment. Under such condition, early period of intervention may do good to slow the progress of silicosis. And specific biomarkers may be critical for early diagnosis, prevention, treatment and finally elimination this disease.
Silicosis (矽肺病), a kind of systematic disease caused by the inhalation of silica dust, characterized mainly by pulmonary (肺 部的） interstitial （ 组织间隙的）fibrosis （纤维化）. Silicosis, a systematic disease caused by the inhalation of silica dust, is mainly characterized by pulmonary interstitial fibrosis.
• 线粒体呼吸链膜蛋白复合物II的结构测定与分析 • Crystal Structure of Mitochondrial Respiratory Membrane Protein Complex II
It is one of the most common detrimental occupational diseases and caused more than nine billion RMB economy losses directly and indirectly in China.1,2 As one of the most common detrimental occupational diseases, silicosis has directly and indirectly caused more than nine billion RMB (financial) losses in China.1,2
Till now, the pathogenesis of silicosis is not clear yet and there are no specific targets for early diagnosis or treatment. However, the pathogenesis of silicosis is not yet clear and specific targets for early diagnosis or treatment have not been found.
Silicosis, a systematic disease caused by the inhalation of silica dust, is mainly characterized by pulmonary interstitial fibrosis. As one of the most common detrimental occupational diseases, silicosis has directly and indirectly caused more than nine billion RMB (financial) losses in China.1,2 There is also a new trend of higher rate of disability among the population exposed to silica dust (even) for a short time, posing a challenge to the prevention and control of this disease. It is therefore necessary to develop early intervention strategies which may be useful / be beneficial in slowing the progress of silicosis. However, the pathogenesis of silicosis is not yet clear and specific targets for early diagnosis or treatment have not been found. Hence, identification of the specific biomarkers may be critical for early diagnosis, prevention, treatment and the eventual elimination of this disease.
As one of the most common detrimental occupational diseases, silicosis has directly and indirectly caused more than nine billion RMB (financial) losses in China.1,2 There is also a new trend of higher degree of disability among the population exposed to silica dust (even) for a short time, posing a challenge to the prevention and control of this disease. Till now, the pathogenesis of silicosis is not clear yet and there are no specific targets for early diagnosis or treatment. Under such condition, early period of intervention may do good to slow the progress of silicosis.
There existed a new trend with higher disability in population of short period silica exposure, and this phenomenon posed challenge to prevent and manage of this disease.
Under such condition, early period of intervention may do good to slow the progress of silicosis. The conditions under which something is done or happens are all the factors or circumstances which directly affect it. (某事完 成或发生的) 条件 例：It's easy to make a wrong turn here under bad weather conditions. 在非常糟糕的天气条件下很容易在这里拐错弯。 It is therefore important/necessary to developies which may be useful / beneficial in slowing the progress of silicosis.
There is also (There also exists) a new trend of higher rate of disability among the population exposed to silica dust (even) for a short time, posing a challenge to the prevention and control of this disease.
And specific biomarkers may be critical for early diagnosis, prevention, treatment and finally elimination this disease.
Hence, identification of the specific biomarkers may be critical for early diagnosis, prevention, treatment and the eventual elimination of this disease.