妊娠合并甲状腺功能亢进症控制状态对妊娠结局的影响

妊娠合并甲状腺功能亢进症控制状态对妊娠
结局的影响
摘要：
目的：本研究旨在探讨妊娠合并甲状腺功能亢进症（Graves病）控制状态对妊娠结局的影响。

方法：对妊娠合并Graves病的孕妇进行观察研究。

根据孕期甲
状腺激素水平、症状控制情况、出生体重等指标来评估孕妇控制状态，关注其孕产妇并发症和新生儿状况。

通过对比控制状态良好和不良两
组孕妇的临床资料，分析其妊娠结局的差异。

结果：研究共招募了170位妊娠合并Graves病的孕妇作为研究
对象。

其中，90位孕妇控制状态良好，80位孕妇控制状态不良。

在妊
娠期，控制状态良好组需要增加剂量更少、甲状腺激素水平控制更稳定；而不良组则会出现甲状腺风暴、恶影响生育体重糖尿病等并发症。

对新生儿的评估表明，控制状态良好组新生儿平均出生体重更高，住
院时间更短，新生儿并发症发生率更低。

结论：妊娠合并Graves病的孕妇若控制状态良好，可以减少孕
产妇并发症和新生儿并发症的发生率，提高出生体重和新生儿健康水平。

因此，对孕妇应该积极监测甲状腺激素水平和症状控制情况，及
时调整药物剂量，保证孕妇甲状腺功能正常，并且确保期间检测孕妇
糖尿病的情况。

关键词：甲状腺功能亢进症，Graves病，妊娠，控制状态，孕妇并发症，新生儿并发症，出生体重。

Abstract:
Objective: The purpose of this study was to investigate the effect of controlled status of Graves' disease on the pregnancy outcome of pregnant women with hyperthyroidism.
Methods: Pregnant women with Graves' disease were
observed and studied. According to the indicators of thyroid hormone levels, symptom control, and birth weight during pregnancy, the control status of pregnant women was evaluated, and the maternal and neonatal conditions were monitored. By comparing the clinical data of well-controlled and poorly controlled pregnant women, the differences in pregnancy outcomes were analyzed.
Results: A total of 170 pregnant women with Graves' disease were enrolled in the study. Of these, 90 pregnant women had good control status, and 80 had poor control status. During pregnancy, the well-controlled group required less
dose increase, and the thyroid hormone levels were more stable; while the poorly controlled group had complications such as thyroid storm and gestational diabetes mellitus. The evaluation of newborns showed that the well-controlled group had a higher average birth weight, shorter hospital stay, and lower incidence of neonatal complications.
Conclusion: Pregnant women with Graves' disease who have good control status can reduce the incidence of maternal and neonatal complications and improve birth weight and neonatal health. Therefore, pregnant women should be actively
monitored for thyroid hormone levels and symptom control, adjust drug doses in a timely manner to ensure normal thyroid function, and ensure the detection of gestational diabetes during this period.
Keywords: hyperthyroidism, Graves' disease, pregnancy, control status, maternal complications, neonatal complications, birth weight.。