干扰素-α1b联合口腔炎喷雾剂治疗小儿手足口病疗效观察

干扰素-α1b联合口腔炎喷雾剂治疗小儿手足口病疗效观察陈其芬;付宏;代勤韵
【期刊名称】《中国医药导报》
【年(卷),期】2011(8)24
【摘要】目的:观察重组人干扰素-α1b联合口腔炎喷雾剂治疗小儿手足口病的疗效及安全性.方法:将98例手足口病患儿随机分为治疗组和对照组,每组各49例.治疗组给予肌注重组人干扰素-α1b联合口腔炎喷雾剂;对照组给予肌注利巴韦林联合蒙脱石散.观察两组疗效.结果:治疗组有效率为87.76%,对照组为63.27%,两组比较,差异有高度统计学意义(P<0.01);治疗组在退热时间、开始进食时间及口腔溃疡愈合时间方面均优于对照组,两组比较,差异均有高度统计学意义(均P<0.01),未发现不良反应.结论:重组人干扰素-α1b联合口腔炎喷雾剂治疗小儿手足口病疗效确切,无不良反应.%Objective: To observe the therapeutic effect of Interferon-α1b combined with Stomatitis Spray in the treatment of hand-foot-mouth disease in children.Methods: 98 children with hand-foot-mouth disease were randomly divided into treatment group and control group, and each group had 49 patients.Children in treatment group were treated with Interferon-α1b combined with Stomatitis Spray.Children in control group were treated with Ribavirin combined with Smecta.The therapeutic effects of the two groups were observed.Results: The effective rate of the treatment group (87.76％) was significantly better than that of the control group (63.27％), and there was a significant difference between two groups (P＜0.01).The defervescence time, the time of intake food and the
disappearing time of mouth ulcers in the treatment group were shorter than those of the control group, and there all were significant differences between two groups (all P＜0.01).No adverse effects occurred.Conclusion: The combination of Interferon-α1b and Stomatitis Spray in the treatment of children with handfoot-mouth disease can improve the clinical effect, with no obvious side effects.
【总页数】2页(P46-47)
【作者】陈其芬;付宏;代勤韵
【作者单位】重庆市江津区中心医院儿科,重庆,402260;重庆市江津区中心医院儿科,重庆,402260;重庆市江津区中心医院儿科,重庆,402260
【正文语种】中文
【中图分类】R725.1
【相关文献】
1.重组人干扰素α1b联合炎琥宁治疗小儿手足口病临床疗效观察 [J], 方敏
2.痰热清注射液联合α1b干扰素雾化治疗小儿手足口病疗效观察 [J], 周卫军
3.重组人干扰素α1b联合炎琥宁治疗小儿手足口病的临床疗效观察 [J], 韩应魁
4.重组人干扰素α1b治疗小儿手足口病的临床疗效观察 [J], 李正兰
5.重组人干扰素α-1b联合蓝芩口服液治疗小儿手足口病的疗效观察 [J], 王艳芳;程光森;冯玉梅
因版权原因，仅展示原文概要，查看原文内容请购买。