Derivatives of endogenous mediators, their salts,
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专利名称：Derivatives of endogenous mediators, their salts, method of preparation, applications
and compositions in which they are present 发明人：Jacques Chauveau,Michel Delaage,Anne
Morel,Louis Segu
申请号：US07/699027
申请日：19910513
公开号：US05298491A
公开日：
19940329
专利内容由知识产权出版社提供
摘要：Derivatives of biologically active molecules containing a primary amine group and a hydroxylated nucleus, and their addition salts with mineral or organic acids, having general formula I:
R'R"N--A--B--O--CH.sub.2 --CO--NH--R (I)
A=linear or branched C.sub.1 -C.sub.5 alkylene;
B=C.sub.4 -C.sub.10 aromatic nucleus with optional heteroatom, or=group --B.sub.1 --X--B.sub. 2 --, wherein X=O or C.sub.1 -C.sub.4 alkylene;
--NH-- R=amine residue or alcohol residue; and
R', R"=C.sub.1 - C.sub.5 alkyl, H or hydrophobic radical, and their addition salts with mineral or organic acids, method of preparation, applications, especially to visualization, purification, the preparation of antibodies and the assay of the total hormone, and as drugs, compositions in which they are present and analytical kits.
申请人：IMMUNOTECH
代理机构：Browdy and Neimark 更多信息请下载全文后查看。