恩替卡韦、胸腺肽α1联合糖皮质激素降阶梯治疗重型乙型肝炎

恩替卡韦、胸腺肽α1联合糖皮质激素降阶梯治疗重型乙型肝
炎
刘运高;卢欣伟;廖群
【期刊名称】《泰山医学院学报》
【年(卷),期】2014(000)007
【摘要】Objective:To investigate clinical efficacy of entecavir,thymosin α1 combined with glucocorticoids step-down therapy for severe hepatitis B. Methods:Sixty patients with severe hepatitis B in our hospital were divided into control group(30)treated with conventional therapy and observation group(30)treated with entecavir ,thymosin α1 combined with glucocorticoids. The clinical efficacy of two groups were compared. Results:Gastrointestinal symptoms remission time and jaundice remission time of observation group were significantly shorter than thsoe in the control group(P ﹤ 0. 05). TBiL level of the observation group was significantly lower than that of the control group and PTA level was significantly higher than that of the control group(P ﹤ 0. 05 ). Conclusion:Clinical efficacy of entecavir,thymosin α1 combined with glu-cocorticoids step-down therapy for severe hepatitis B is significant.%目的：总结分析恩替卡韦联合胸腺肽α1、糖皮质激素治疗重型乙型肝炎的临床效果。

方法选择60例重型乙型肝炎患者为研究对象，随机分为观察组和对照组各30例，对照组患者给予常规治疗方案，观察组患者在常规治疗基础上给予恩替卡韦、胸腺肽α1、糖皮质激素治疗。

结果观察组患者消化道症状缓解时间、黄疸缓解时间明
显短于对照组（P ﹤0.05）；治疗后观察组 TBiL 水平明显低于对照组，而 PTA 水平明显高于对照组，差异具有统计学意义（P ﹤0.05）。

结论恩替卡韦联合胸腺肽α1、糖皮质激素降阶梯治疗重型乙型肝炎的临床效果显著。

【总页数】2页(P608-609)
【作者】刘运高;卢欣伟;廖群
【作者单位】阳西县人民医院，广东阳江 529800;阳西县人民医院，广东阳江529800;阳西县人民医院，广东阳江 529800
【正文语种】中文
【中图分类】R512.6+2
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