Finasteride acetate_222989-99-3_DataSheet_MedChemExpress
2022年最新阿考替胺杂质系列全套资料
2022年最新阿考替胺杂质系列全套资料以下信息整理自恒丰万达药物杂质网产品货号CAS号分子式分子量结构式阿考替胺A014000N/A C21H30N4O5S450.55盐酸阿考替胺A014000A185104-11-4C21H31ClN4O5S487.01阿考替胺杂质1A01400140283-41-8C4H4N2O2S144.15阿考替胺杂质2A014002118452-04-3C5H6N2O2S158.18阿考替胺杂质3A0140035722-93-0C9H10O5198.17阿考替胺杂质4A014004877997-98-3C15H14O5274.27阿考替胺杂质5A014005185106-01-8C14H14N2O6S338.34阿考替胺杂质6A014006185103-81-5C22H33ClN4O5S501.04阿考替胺杂质7A014007206882-15-7C12H22N4OS270.39阿考替胺杂质8A0140081809272-85-2C13H12N2O6S324.31阿考替胺杂质9A014009948053-83-6C6H10N4OS186.23阿考替胺杂质10A014010185106-05-2C15H16N2O6S352.36阿考替胺杂质11A014011N/A C17H20N2O8S412.41阿考替胺杂质12A014012185105-98-0C16H18N2O6S366.39阿考替胺杂质13A014013185106-16-5C21H30N4O5S450.55阿考替胺杂质15A014015N/A C16H18N2O6S366.39阿考替胺杂质16A014016N/A C8H6N4O3S2270.29阿考替胺杂质17A014017N/A C13H13ClN2O6S360.77阿考替胺杂质18A014018N/A C14H15ClN2O6S374.8阿考替胺杂质20A014020N/A C19H27BrN4O5S503.41阿考替胺杂质21A014021738562-93-1C20H29BrN4O5S517.44阿考替胺杂质22A014022877997-99-4C14H14N2O6S338.34阿考替胺杂质23A014023877998-00-0C15H18N2O7S370.38阿考替胺杂质24A014024N/A C6H8N2O2S172.2阿考替胺杂质25A014025N/A C10H12O5212.2阿考替胺杂质26A014026N/A C17H28N2O4324.42阿考替胺杂质27A014027N/A C18H24N4O5S408.47阿考替胺杂质28A014028N/A C21H32N4O6S468.57阿考替胺杂质29A014029N/A C13H14N2O7S342.32阿考替胺杂质31A014031N/A C20H20N4O7S2492.53阿考替胺杂质32A014032N/A C14H14N4O6S2398.41阿考替胺杂质33A014033N/A C14H14N2O6S338.34阿考替胺杂质34A014034N/A C15H16N2O6S352.36阿考替胺杂质35A014035N/A C15H16N2O6S352.36阿考替胺杂质36A014036N/A C21H29N3O6S451.54阿考替胺杂质37A01403767370-98-3C8H8O5184.15阿考替胺杂质38A014038610-90-2C7H6O5170.12阿考替胺杂质39A014039N/A C8H8O5184.15阿考替胺杂质40A014040N/A C9H10O5198.17阿考替胺杂质42A014042N/A C9H10O5198.17阿考替胺杂质43A014043N/A C9H11ClO3202.63阿考替胺杂质44A014044N/A C4H4Br2O3259.88阿考替胺杂质45A014045N/A C5H8O4132.11阿考替胺杂质46A014046N/A C9H8O4180.16阿考替胺杂质47A014047N/A C20H28N4O5S436.53阿考替胺杂质48A014048N/A C10H12N2O4S256.28阿考替胺杂质49A014049N/A C15H17N3O6S367.38阿考替胺杂质50A014050N/A C17H14N4O7S2450.45阿考替胺杂质51A014051N/A C18H16N4O7S2464.47阿考替胺杂质53A014053N/A C18H16N4O7S2464.47。
依美斯汀
药动学
临床研究中5例健康志愿者单剂量0.5、1、2mg和4mg餐后顿服,其后1例空腹服用2mg并加倍剂量。使用0.5、 1、2mg和4mg单剂量在1.14~1.83h达到最高血浆药物浓度,分别为0.736、1.30、2.76及4.10ng/ml。血浆半衰 期分别为2.76、2.96、3.16和4.12h。餐后服用与空腹服用相比,血浆药物浓度峰值和达峰时间明显增大,重复 给药,在3天后达到稳态浓度。给另一组使用本品单剂量的缓释胶囊(2mg和8mg)和复合剂量(1次2mg,2次/d,连 续14天),测其药代动力学。2mg和8mg单剂量的最高血药浓度各自为1.26ng/ml和4.96ng/ml,达峰时间为3.05h 和5.38h,半衰期为6.98h和8.67h。使用复合剂量5天后达稳态浓度,餐后服与复合剂量使用比较,峰和谷之间只 有较小的差异。
物化性质
密度:1.15 g/cm3 熔 点 : 1 4 8 - 1 5 1 ºC 沸点:446.6ºC at 760 mmHg 闪 点 : 2 2 3 . 9 ºC 折射率:1.594
分类名称
一级分类:皮肤科用药二级分类:抗炎症介质类药物三级分类:H1受体阻断剂
药品名称
英文名:Emedastinc 药品别名:Daren、依美斯汀酯、Emedastinc Difumarate
基本信息
中文名称:依美司丁 中文别名:1-(2-乙氧基乙基)-2-(4-甲基-1,4-二氮杂庚烷-1-基)苯并咪唑;依美斯汀; 英文名称:emedastine 英文别名:1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)benzimidazole; 1-[2(ethoxy)ethyl]-2-(4-methyl-1-homopiperazinyl)benzimidazole; Emedastinum [INN-Latin]; Emedastina; 1-methyl-4-(1-(2-ethoxyethyl)-1H-benzimidazol-2-yl)[1,4]diazepane CAS号:-61-2 分子式:C17H26N4O 化学结构: 分子量:302. 精确质量:302. PSA:33.
恩曲替尼化学式-概述说明以及解释
恩曲替尼化学式-概述说明以及解释1.引言1.1 概述概述恩曲替尼(英文名称:Entrectinib)是一种靶向抗癌药物,属于酪氨酸激酶抑制剂。
它通过抑制肿瘤细胞中的激酶信号通路,发挥抗肿瘤的作用。
恩曲替尼被广泛应用于非小细胞肺癌、神经母细胞瘤和其他肿瘤的治疗。
该药物的化学性质使其具备出色的抗肿瘤效果。
恩曲替尼的分子式为C31H34Cl2N5O3,分子量为602.54克/摩尔。
其分子结构复杂,由多个不同原子组成的编织网状结构构成。
这种特殊的结构赋予了恩曲替尼优异的特性,包括其强大的抑制肿瘤生长能力和独特的靶向治疗机制。
除了化学性质外,恩曲替尼还具有一系列独特的物理性质。
该药物为白色或类白色结晶粉末,具有极高的纯度要求。
其熔点为210-215,在这个温度范围内可以保持稳定。
此外,恩曲替尼在常温下可溶于一些有机溶剂,如二氯甲烷和二甲基亚砜,但不溶于水。
在药理作用方面,恩曲替尼主要表现出针对肿瘤细胞的抗增殖和抗转移能力。
它通过干扰肿瘤细胞的激酶信号通路,阻止肿瘤细胞的分裂和生长。
此外,恩曲替尼还具有特异性靶向治疗作用,能够选择性地抑制特定的激酶,从而实现精确的治疗效果。
然而,恩曲替尼也存在一些副作用,如恶心、呕吐、疲劳和食欲不振等,这些副作用需在使用时留意并及时处理。
综上所述,恩曲替尼作为一种靶向抗肿瘤药物,具有复杂的化学性质、独特的物理性质以及较广泛的药理作用。
进一步的研究和应用将有助于更好地发掘恩曲替尼的潜力,为肿瘤治疗提供新的突破和可能性。
1.2 文章结构文章结构部分的内容如下:文章结构部分主要介绍了整篇文章的组织结构和内容安排。
本文的目录分为引言、正文和结论三个部分。
引言部分主要是对整篇文章的背景和目的进行概述,并对恩曲替尼的化学式进行引入。
接着,文章结构部分将详细介绍恩曲替尼的化学性质、物理性质和药理作用。
最后,结论部分将对恩曲替尼的化学性质、物理性质和药理作用进行总结。
在正文部分,恩曲替尼的化学性质将包括分子式、分子量和结构式的介绍。
50%压缩比导电乙炔炭黑材料安全数据MSDS中英文
炭黑的外泄暴露,除了会弄脏周围环境外没有发现会对环境造成严重的影响或损害。Exposure to carbon black leakage will not only dirty the surrounding environment but also has not been found to have a serious impact or damage on the environment.
皮肤接触Skin Contact:
及时用大量水及温和性肥皂缓和但彻底的清洗,若仍有刺激感,立即就医。
Cleanse promptly with a lot of water and mild soap, but thoroughly.If there is still irritation, seek medical attention immediately.
特殊灭火程序
Special fire extinguishing procedures:
1.炭黑储区火灾时,建议采用二氧化碳灭火器。
When there is a fire in the carbon black storage area, it is recommended to use a carbon dioxide fire extinguisher.
吸入Inhalation:
长期大量地由呼吸道吸入炭黑粉尘,可能最终造成对肺部的损伤。目前,没有明确的医学报道证明炭黑会引起癌变的结果。但可以列入人类的可能致癌的物质。
Long-term inhalation of carbon black dust in large quantities may eventually cause lung damage. Currently, there are no clear medical reports to prove that carbon black can cause cancer. However, it can be listed as a possible carcinogen.
印度
1 Sherry Chemicals & Pharmaceuticals (P) Ltd.( Online Catalog)Manufacturer, exporter, distributor, supplier and trader of citric acid, acid, phosphoric acid, acid Address : 1/50, Ganga Apartments, LG-1 T0 LG-3, Lalita Park, Laxmi Nagar, Vikas Marg, Delhi - 110092, IndiaPhone : 91-11-27050240/43632707Mobile : +919899667748Fax : 91-11-436327072 KEMFIN CHEMICALS (P) LTD./Seller-1144131-KEMFIN-CHEMICALS-P-LTD-/#contactAddress 41 KM, KHANDAWALI ROAD, Ballabgarh - 121004, Haryana, IndiaPhone 91-129-2205556Mobile +919810089212Fax 91-129-22052563 TRIVENI INTERCHEM PVT. LTD.Address : 134, PANCHARATNA, CHAR RASTA, G.I.D.C., Vapi - 396195, Gujarat, India Phone : 91-260-6618618 Mobile : +919227788155 Fax : 91-260-66186244Arrow Fine ChemicalsAddress : Plot No. G-1023, Road 1-A, Kishan Gate, Lodhika, G.I.D.C., Kalawad Road, Metoda, Rajkot - 360021, Gujarat, IndiaPhone : 91-2827-287878Mobile : +919925500777Fax : 91-2827-2878785Suboneyo Chemicals Pharmaceuticals Private LimitedAddress : A, 86-89, M.I.D.C., Industrial Area, Jalgaon - 425003, Maharashtra, IndiaPhone : 91-257-2211754/2211756Mobile : +919371999999Fax : 91-257-2210748/2212264/6Neuchatel Chemie SpecialtiesAddress : D-1/38, Prachi Society, Shahji Raje Marg, Vile Parle (East), Mumbai - 400057, Maharashtra, IndiaPhone : 91-22-26825251/26827129Mobile : +919322228449Fax : 91-22-268386297Prakash Chemicals Agencies Pvt. Ltd.Address : PRAKASH HOUSE, 39-40, Krishna Estate, Opp. Gorwa BIDC, Vadodara - 390016, Gujarat, IndiaPhone : 91-265-3926112Mobile : +919998034403Fax : 91-265-3926122, 8 SURYA EXIM LTD.Address : 3040, Jash Textile & Yarn Market, Ring Road, Surat - 395002, Gujarat, IndiaPhone : 91-261-4083100/4083104Mobile : +919924111593Fax : 91-261-4083120/23288428H & H EXPORTS (GUJ) PVT LTDAddress : 901, Shapath-1, Opp. Rajpath club, S.G. Highway, Ahmedabad - 380015, Gujarat, India Phone : 91-79-26872838/26872979Mobile : +919825035271Fax : 91-79-40035319/Exporters_Suppliers/Exporters/hp/31928/about_us.html9Navyug Pharmachem Pvt. Ltd.Address : Survey NC-260/2, Navagam-Sodwadar Road, Navagam (Kardej), Bhavnagar - 364060, Gujarat, IndiaPhone : 91-278-2540136/2541836/2541679Mobile : +919825205310Fax : 91-278-2428022/254167910 Jay Intermediates And Chemicals, Address : Jay House, Plot No. 731, Phase II, 40 Shed Area, G.I.D.C., Vapi - 396195, Gujarat, India Phone : 91-260-2436232/2436317Mobile : +919898437973Fax : 91-260-243631711 BILSTON ORGANICSAddress : 1, Villanganoor Village, Melmaruvathoor via, Cheyyoour, Kanchipuram - 603313, Tamil Nadu, IndiaPhone : 91-44-27533640Mobile : +919710860705Fax : 91-44-2753364012 Ramniklal S. Gosalia & Co.Address : National House, 608, B.J. Marg, Jacob Circle, Mahalaxmi, Mumbai - 400011, Maharashtra,IndiaPhone : 91-22-23063821/23063826/23063827Mobile : +919833831150Fax : 91-22-2306382813 Charotar Casein CompanyAddress : 11, Firdosh Park, Barkosiya Road, Malharpura, Nadiad - 387001, Gujarat, IndiaPhone : 91-268-2532825/2559361Mobile : +919825398440Fax : 91-268-2532824/14 Aroma AgenciesAddress : 2, Ratnadeep, Mahant Road Extn., Vile Parle East, Mumbai - 400057, Maharashtra, India Phone : 91-22-26173707/26173708/26111653/26161316Mobile : +919819900631Fax : 91-22-26124315/15 Chemtex Speciality LtdAddress : 'Chemtex House', 33, Brabourne Road, Kolkata - 700001, West Bengal, IndiaPhone : 91-33-22424546Mobile : +919861111111Fax : 91-33-22423329/2321861516 Venki ChemAddress : A/5-201, Yogi Dham, Yogi Nagar, Eksar Road, Borivali (W), Mumbai - 400091, Maharashtra, IndiaPhone : 91-22-65093814/65093815Mobile : +919223433053Fax : 91-22-2895238417 Suvidhi Industries/Address : Plot No. 572, Shed No. C-1B/73, 100 Shed Area, G.I.D.C., Vapi - 396195, Gujarat, India Phone : 91-260-2453194/3295499/6543194Mobile : +919099019618Fax : 91-260-245142918 Excel InternationalAddress : B-10, Super Shopping Complex, Dr. Dalvi Road, Near Vyas Classes, Kandivali (W), Mumbai - 400067, Maharashtra, IndiaPhone : 91-22-65232393Mobile : +919769094794Fax : 91-22-28622204http://www.excelintl.co.in19 Aquatic ChemicalsAddress : 202, Kuntal, Mody Estate, Near Pipeline, LBS Marg, Ghatkopar (W), Mumbai - 400086,Maharashtra, IndiaPhone : 91-22-25121364/67033663Mobile : +919920993775Fax : 91-22-67033663/20 Kem Light Laboratories Pvt. Ltd.Address : 401/406, Sarita, "B" Wing, 4th floor, Prabhat Industrial Complex, Western Express Highway, Dahisar (East), Mumbai - 400068, Maharashtra, IndiaPhone : 91-22-28281500/28281501Mobile : +919987701501Fax : 91-22-28282000/2828100021 Siddhivinayak Trading Co.Address : 205/206, SAPPHIRE Complex, 21, New Jagnath Plot, Sarveshwar Chowk, Rajkot - 360001, Gujarat, IndiaPhone : 91-281-2468567/2467555Mobile : +919825074994Fax : 91-281-2468567/2467555/22 Kgn Enterprises Ltd.Address : 315, 316-1, 318, Kheda-Dholka Highway, Hariyala Kheda, Kheda - 387411, Gujarat, India Phone : 91-2694-291043Mobile : +919825023899Fax : 91-2694-22446123 K. N. CeramicsAddress : Village Kumbh, Amloh Road, Mandi Gobindgarh - 147301, Punjab, IndiaPhone : 91-1765-657289Mobile : +919872804289Fax : 91-1765-25428924 Krishna EnterprisesAddress : 4/27, Bapat (Shradha) Bldg, Gokhale Road North, Dadar (W), Mumbai - 400028, Maharashtra, IndiaPhone : 91-22-24212364/24211824Mobile : +919322280617Fax : 91-22-2421182425 Vats InternationalAddress : LD-38, Pitampura, Delhi - 110034, IndiaPhone : 91-11-27318917/27312421Mobile : +919810131850Fax : 91-11-27311126/vats-international26 Credence SpecialtiesAddress : 603, Siddhartha Complex, R.C.Dutt Road, Alkapuri, Vadodara - 390007, Gujarat, India Phone : 91-265-3059846Mobile : +919898003678Fax : 91-265-234220127 Chempack IndustriesAddress : Plot No. 7410, 11-12, Gidc, Nr. Karma Tur Chokdi, Ankleshwar - 393002, Gujarat, India Phone : 91-2646-220848Mobile : +919426285423Fax : 91-2646-220848/chempackindustries28 Spr Chemicals Pvt. Ltd.Address : B-5 & C-6, Pushpa Bhawan, Alakhanda Commercial Complex, New Delhi - 110019, India Phone : 91-11-26021163Mobile : +919810238760Fax : 91-11-26021801http://www.sprgroup.in29 Dmt InternationalAddress : Emrald Plaza, Block No.3, Shop No.20, Hiranandani Meadows, Thane (W), Thane - 400607, Maharashtra, IndiaPhone : 91-22-40123275/25896148Mobile : +919833865725Fax : 91-22-4012614830 Himalaya ChemicalsAddress : Shed No. C-1, B-3-4, Plot No. 24-25, G.I.D.C Estate, Pandesara, Surat - 394221, Gujarat, IndiaPhone : 91-261-2890466/2890591Mobile : +919825123566Fax : 91-261-289086631 M. K. Medical ServicesAddress : C-2/16, Jai Matadi Compound, Kasheli, Kalher, Bhiwandi, Thane - 421302, Maharashtra, IndiaMobile : +91986908887732Panorama Aromatics Ltd.Address : 711, Sidharth Complex, R.C. Dutt Road, Vadodara - 380007, Gujarat, IndiaPhone : 91-265-3088893/3088894/3088895Mobile : +919825021759Fax : 91-265-235908133Prime IndustriesAddress : 342, GIDC Estate, Phase-2, Dediyasan, Mehsana - 384002, Gujarat, IndiaPhone : 91-2762-224123Mobile : +919879006651Fax : 91-2762-224123/34 Iyappan & Co.Address : New No. 31/12, 2nd Floor, Malleeswarar Koil Street, Mylapore, Chennai - 600004, Tamil Nadu, IndiaPhone : 91-44-24671109Mobile : +919840891033Fax : 91-44-2467110935Central Drug House (P) Ltd.Address : 7/28, Vardaan House, Ansari Road, Darya Ganj, New Delhi - 110002, IndiaPhone : 91-11-49404040 (100 Lines)Mobile : +919811154379Fax : 91-11-49404050/2328093236KemikorpAddress : 403, Chamundeshwari Tower, 7-1-64/1, Dharam Karan Road, Ameerpet, Hyderabad - 500016, Andhra Pradesh, IndiaPhone : 91-40-23755051/23745051/66365051Mobile : +919848045600Fax : 91-40-2375476637Altis Finechem Pvt. Ltd.Address : Near Katwad Patya, Behind VRN Ceramic Ltd. At. Dalpur, Taluka Prantij, Himatnagar - 383120, Gujarat, IndiaPhone : 91-2772-324183/91-2770-240713Mobile : +917698045799/38Shanta ChemicalsAddress : 6, SHREE GANESH, PLOT NO.1, SEC-28, NERUL (w), Navi Mumbai - 400706, Maharashtra, IndiaPhone : 91-22-64460550/27700019Mobile : +919867921790Fax : 91-22-64460550/27700019。
Phanta超高保真酶
1.引物3’端最后一个碱基选择C或G; 2.引物3’端最后8个碱基应避免出现连续错配; 3.引物3’端尽量避免出现发夹结构; 4.引物Tm值控制在55℃-65℃之间; 5.引物额外附加序列,即与模板非配对序列,不应参与引物Tm值计算; 6.引物GC含量控制在40%-60%之间; 7.正向引物和反向引物Tm值以及GC含量尽可能一致。
应用实例
1.反应体系配制:
所有操作请在冰上进行,各组分解冻后请充分摇匀。为了防止PhantaTM Super-Fidelity DNA Polymerase的校对活性降解引物,请将聚合酶最后加入反应体系中。各组 分使用完毕后及时放回-20℃。5 × SF Buffer请勿长时间敞口放置。
ddH2O 5 × SF Buffer (with 10 mM MgSO4) 25 mM MgSO4a dNTP Mix (10 mM each)b
a. 对于大多数PCR反应,Mg2+最佳终浓度为1.5-2 mM。体系中已含有终浓度为2 mM Mg2+,如有需要,可用25 mM MgSO4,以0.2-0.5 mM为间隔向上摸索Mg2+最佳 使用浓度。
b. 请勿使用dUTP和带有尿嘧啶的引物或模板。 c. 扩增子GC含量>60%时加入终浓度3%的DMSO有可能会有助于扩增。 d. 推荐仅当扩增子GC含量>60%且优化条件也无法正常扩增时使用;可能会降低保真度。 e. 不同模板最佳反应浓度有所不同,下表为50 μl反应体系推荐模板使用量:
DMSOc
5 × PCR Enhancerd
模板DNAe
引物1 (10 μM)
引物2 (10 μM)
PhantaTM Super-Fidelity DNA Polymerase (1 U/μl)f
阿司咪唑
合成方法
合成方法
化合物(I)和碘甲烷在乙醇中回流8h,环合得到化合物(Ⅱ)。再水解脱去酯基,得到化合物(Ⅲ)。用对甲氧 基苯乙基溴进行N-烷基化,得化合物(Ⅳ)。再用对氟苄基溴烷基化,得阿司咪唑。
1. 1-[(4-氟苯基)甲基]-苯并咪唑-2-(3H)-酮的制备
在反应瓶中加入2-羟基苯并咪唑5.0g(37.3mmol)和NaH 1.6g(53mmol)(NaH含量大约为80%,浸入矿物油中) 的DMF 100ml的悬浮液.加毕.在60ºC.(最好有N2保护)搅拌反应1h.再加入4-氟苄基氯(FBC)5.4g(37mmol),加热 ( 6 0 ºC ) 搅 拌 反 应 5 . 5 h . 冷 却 至 室 温 后 加 入 冰 水 7 0 0 m l , 用 二 氯 甲 烷 ( 5 0 0 m l × 2 ) 提 取 . 有 机 层 用 食 盐 水 洗 . 无 水 N a 2 S O 4 干燥.过滤.滤液减压浓缩.剩余物用石油醚析晶.得1-[(4-氟苯基)甲基]-苯并咪唑-2-(3H)-酮固体8.0g,为无色 结 晶 m p 1 7 8 ~ 1 7 9 ºC , 收 率 8 8 % .
治疗措施
阿司咪唑中毒的治疗要点为: 1.大量摄入者予洗胃,后灌服活性炭和导泻。 2.对心肌抑制和Q-T间期延长者予5%碳酸氢钠250ml静注可能有效。 3.对症、支持治疗。
专家点评
专家点评
阿司咪阿司咪唑自1983年上市以来,在许多国家得到了广泛应用。国外研究显示阿司咪唑治疗荨麻疹的总有 效率为74%。国内的一项多中心双盲安慰剂对照试验表明阿司咪唑对急性荨麻疹的总有效率为82.9%,对慢性荨麻 疹的总有效率为86.0%,均显著高于安慰剂,主要不良反应为嗜睡、倦怠、口干等,连续用药3个月的患者中,半 数有食欲及体重增加。阿司咪唑的心脏毒性虽然发生率较低,但由于后果严重,已限制了它的应用。阿司咪唑为 强效和长效的H1受体拮抗剂,无中枢镇静和抗毒蕈碱样作用。代谢产物去甲阿司咪唑仍有抗胆胺作用。长期服用 可增进食欲和增加体重,服用过量可引起心脏Q-T间期延长和室性心律失常。适用于各种原因引起过敏性疾病。
Hi-Yield Range和Pasture Clopyralid 3 安全数据表说明书
SAFETY DATA SHEETEMERGENCY CALL: 1-800-424-9300 (CHEMTREC)PRODUCT NAME: Hi-Yield ® Range and Pasture Clopyralid 3DESCRIPTION: A liquid herbicide.EPA Reg. No.: 81927-14-7401COMPANY IDENTIFICATION:Voluntary Purchasing Groups, Inc.230 FM 87Bonham, TX 75418WARNINGHarmful if inhaledFlammable liquid and vapor May be harmful in contact with skinCauses eye irritationCommon Name Chemical Name CAS # Composition Clopyralid(3,6-Dichloro-2-pyridinecarboxylic acid), Monoethanolamine salt 57754-85-5 40.9% Isopropanol Isopropyl alcohol 67-63-0 unknownHave the product container or label with you when calling a poison control center or doctor or going for treatment. You may also contact CHEMTREC at 1-800-424-9300 for emergency medical information. IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a doctor or poison control center if you feel unwell.IF ON SKIN OR CLOTHING: Take off contaminated clothing and wash before reuse. Rinse skin immediately with plenty of water. If skin irritation or rash occurs: call a poison control center or doctor for treatment advice.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists, get medical advice/attention.NOTE TO PHYSICIAN: No specific antidote is available, treat symptomatically.Flash point: 47.2°C (117°F)Flammable Limits (LFL-UFL): Not determinedFire and Explosion Hazards: May thermally decompose in fire releasing irritating and toxic fumes. Extinguishing Medium: Water fog, alcohol resistant foam, dry chemical or carbon dioxide (CO 2).Fire Fighting Equipment: Firefighters should be equipped with self-contained positive pressure breathing apparatus and full bunker gear.Fire Fighting Instructions: Evacuate area of all unnecessary personnel and fight fire from a safe distance upwind. Contain contaminated water / firefighting water; do not allow to enter drains or waterways. Foam or dry chemical fire extinguishing systems are preferred to prevent environmental damage from excessive water runoff.NFPA Ratings: Health – 2 / Flammability –2 / Reactivity - 1Personal Precautions: Isolate area and keep unnecessary and unprotected personnel from entering. Wear suitable personal protective clothing and equipment as described in Section 8 of this document. Small Spills: Absorb using sand, vermiculite or other inert absorbent. Place contained material in appropriate container for disposal.Large Spills: Dike spillage and recover and retain as much free liquid as possible for reuse. Pick up remainder with suitable absorbent material. Place into suitable containers for reuse or disposal in a licensed facility. After removal, thoroughly clean contaminated area with water. Collect wash water for approved disposal.Do not swallow and avoid contact with eyes, skin and clothing. Use only in a well-ventilated area. Wear appropriate personal protective clothing and equipment (see Section 8 below). Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. Store above 28°F or warm to 40°F and agitate before use.Engineering Controls:Proper ventilation is required when handling or using this product to keep exposure to airborne contaminants below the exposure limit. Local mechanical exhaust ventilation may be required. Facilities storing or utilizing this material should be equipped with an eyewash station and a safety shower.Protective Clothing: Wear long sleeved shirt, long pants, shoes, socks, and chemical resistant gloves made of any waterproof material.General: Wash clothing and other absorbent materials that have been exposed to this product. Follow the manufacturer’s instructions for cleaning and maintaining PPE. If no su ch instructions for washables exist, use detergent and hot water. Keep and wash PPE separately from other laundry.Physical State: Reddish-brown LiquidOdor: SweetpH: 7.5 – 8.0Specific Gravity: 1.161 @ 20°CVapor Pressure: 23.5mmHg @ 20°CSolubility: MiscibleCONDITIONS TO AVOID: Direct sunlight, open flame and temperatures close to the flash point (117°F). CHEMICAL STABILITY: Stable under all normal use and storage conditions. May decompose if heated. HAZARDOUS DECOMPOSITION PRODUCTS: Hydrogen chloride and oxides of nitrogen. INCOMPATIBILITY WITH OTHER MATERIALS: Do not use with or store near oxidizing agents, acids, halogenated organics, brass, copper, zinc, or aluminum.HAZARDOUS REACTIONS: This product is chemically stable and no hazardous reactions should occur if stored and handled as prescribed / indicated.POLYMERIZATION: Will not occur.ORAL TOXICITY (rat LD50): > 5,000 mg/kgDERMAL TOXICITY (rat LD50): > 2,000 mg/kgINHALATION TOXICITY (rat LC50): > 2.1 mg/L (4-hour)EYE IRRITATION: Moderately irritatingSKIN IRRITATION: Slightly irritatingSKIN SENSITIZATION: Not a contact sensitizerCARCINOGENICITY:EPA:Not ListedACGIH: Not Listed NTP:Not ListedIARC:Not Listed OSHA: Not ListedMUTAGENIC TOXICITY: Little evidence of mutagenic effects during in vivo and in vitro assays. REPRODUCTIVE TOXICITY: No evidence in animal studies.Clopyralid is a chemical which can travel (seep or leach) through soil and under certain conditions contaminate groundwater which may be used for irrigation or drinking purposes. Users are advised not to apply clopyralid where soils have a rapid to very rapid permeability throughout the profile (such as loamy sand to sand) and the water table of an underlying aquifer is shallow, or to soils that would allow direct introduction into an aquifer. Your local agricultural agencies can provide further information on the type of soil in your area and the location of groundwater.Do not contaminate water, food or feed by disposal.PESTICIDE DISPOSAL: Wastes resulting from the use of this product may be disposed of on site or at an approved waste disposal facility.CONTAINER DISPOSAL:Nonrefillable container. Do not reuse or refill this container. Refer to the product label for specific container handling instructions.US DOT (shipped by land):Containers < 119 Gallons:Not regulated by DOT.Containers > 119 Gallons:DOT Shipping Name: NA1993, Combustible Liquid, N.O.S. (contains isopropanol), PG III DOT Emergency Response Guide: 128SHIPMENTS BY AIR OR VESSEL:DOT Shipping Name: UN1993, Flammable Liquid, N.O.S. (contains isopropanol), 3, PGIIIReportable Quantity (RQ): None.DOT Emergency Response Guide: 128Marine Pollutant: NoFIFRA –This chemical is a pesticide product registered by the Environmental Protection Agency and is subject to certain labeling requirements under federal pesticide law. These requirements differ from the classification criteria and hazard information required for safety data sheets, and for workplace labels of non-pesticide chemicals. The following is the hazard information as required on the pesticide label: PRECAUTIONARY STATEMENTSHAZARDS TO HUMANS AND DOMESTIC ANIMALSCAUTION: Harmful if absorbed through skin. Avoid contact with eyes, skin or clothing.See inside label booklet for additional Precautionary Statements and Directions for Useincluding Storage and Disposal instructions.ENVIRONMENTAL HAZARDSDo not apply directly to water, to areas where surface water is present, or to intertidal areasbelow the mean high water mark. Do not contaminate water when disposing of equipmentwashwaters. Do not contaminate water used for irrigation or domestic purposes.Clopyralid is a chemical which can travel (seep or leach) through soil and under certainconditions contaminate groundwater which may be used for irrigation or drinking purposes.Users are advised not to apply clopyralid where soils have a rapid to very rapid permeabilitythroughout the profile (such as loamy sand to sand) and the water table of an underlyingaquifer is shallow, or to soils that would allow direct introduction into an aquifer. Your localagricultural agencies can provide further information on the type of soil in your area and thelocation of groundwater.All pesticides are governed under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). The regulatory information presented below is pertinent only when this product is handled outside of the normal use and application as a pesticide. This product is excluded from listing requirements under EPA/TSCA.SARA Title III – Section 302 Extremely Hazardous SubstancesNot listedSARA Title III – Section 311/312 Hazard CategoriesImmediate, Delayed, FireSARA Title III – Section 312 Threshold Planning QuantityN/ASARA Title III – Section 313 Reportable IngredientsIsopropyl alcohol (CAS No. 67-63-0)CERCLA –Not listedCALIFORNIA PROP 65 STATUS –This product does not contain any chemicals known to the state of California to cause cancer or reproductive toxicity.CANADA –This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and the SDS contains all of the information required by CPR.This Safety Data Sheet (SDS) serves different purposes than and DOES NOT REPLACE OR MODIFY THE EPA APPROVED PRODUCT LABELING (attached to and accompanying the product container). This SDS provides important health, safety, and environmental information for employers, employees, emergency responders and others handling large quantities of the product in activities generally other than product use, while the labeling provides that information specifically for product use in the ordinary course.Use, storage and disposal of pesticide products are regulated by the EPA under the authority of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) through the product labeling, and all necessary and appropriate precautionary, use, storage, and disposal information is set forth on that labeling. It is a violation of Federal law to use a pesticide product in any manner not prescribed on the EPA-accepted label.Although information and recommendations set forth herein (hereinafter “Information”) are presented in good faith and believed to be correct as of the date hereof, Voluntary Purchasing Groups, Inc. makes no representations as to the completeness or accuracy thereof. Information is supplied upon the condition that the persons receiving same will make their own determination as to its suitability for their purposed prior to use. In no event will Voluntary Purchasing Groups, Inc. be responsible for damages of any nature whatsoever resulting from the use of or reliance upon information. NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, OF MERCHANTABILTY, FITNESS FOR A PARTICULAR PURPOSE OR OF ANY OTHER NATURE ARE MADE HEREUNDER WITH RESPECT TO INFORMATION OR THE PRODUCT TO WHICH INFORMATION REFERS.Hi-Yield is a registered trademark of Voluntary Purchasing Groups, Inc.SDS Version: 1.0 Effective Date: 07/24/2015。
安捷伦产品目录
15
Real-Time PCR
16
Mx3000P QPCR System
17
Brilliant III Ultra-Fast SYBR Green QPCR and QRT-PCR Reagents
18
Brilliant III Ultra-Fast QPCR and QRT-PCR Reagents
Agilent / STRATAGENE
Agilent website: /genomics
Welgene | Agilent Stratagene
威健股份有限公司 | Stratagene 總代理
Table of Content
Table of Contents
/ XL1-Red Competent Cells SoloPack Gold Supercompetent Cells
/ TK Competent Cells Specialty Cells
/ Classic Cells / Fine Chemicals For Competent Cells
適用於 UNG 去汙染或 bisulphite
sequencing
適用於 TA Cloning
最高敏感性
取代傳統 Taq 的好選擇
-
2
威健股份有限公司 | Stratagene 總代理
PCR Enzyme & Instrument
Agilent SureCycler 8800
市場上領先的 cycling 速度和 sample 體積 10 ~ 100 μL 簡易快速可以選擇 96 well 和 384 well 操作盤 優秀的溫控設備讓各個 well 都能保持溫度的穩定 七吋的高解析度觸控螢幕讓操作上更為簡便 可以透過網路遠端操控儀器及監控儀器 Agilent 專業的技術支援可以幫助您應對各種 PCR 的問題
非那雄胺杂质汇总
非那雄胺杂质2
(Finasteride EP 103335-41-7
Impurity B)
10mg 25mg 50mg 100mg 更大规格请咨询
项目报批 纯度高于98%
Finasteride Impurity 3
非那雄胺杂质3
(Finasteride EP 1800205ቤተ መጻሕፍቲ ባይዱ94-0
Impurity C)
非那雄胺杂质列表集
中文名称
英文名称
CAS
Finasteride Impurity 1
非那雄胺杂质1
(Finasteride EP
98319-24-5
Impurity A)
规格
10mg 25mg 50mg 100mg 更大规格请咨询
用途
项目报批 纯度高于98%
结构式
Finasteride Impurity 2
10mg 25mg 50mg 100mg 更大规格请咨询
项目报批 纯度高于98%
非那雄胺杂质4 Finasteride Impurity 4 133216-45-2
10mg 25mg 50mg 100mg 更大规格请咨询
项目报批 纯度高于98%
非那雄胺杂质5 Finasteride Impurity 5 166896-74-8
10mg 25mg 50mg 100mg 更大规格请咨询
项目报批 纯度高于98%
扬信医药代理各品种杂质对照品:舒更葡糖钠杂质,达托霉素杂质,依维莫司杂质,他克莫司杂质,阿奇霉素杂质,克拉维酸钾杂质, 红霉素杂质,克拉霉素杂质,林可霉素杂质,罗红霉素杂质,克林霉素杂质,恩曲他滨杂质,艾地那非杂质,瑞卢戈利杂质,艾氟康唑 杂质等;并提供COA、NMR、HPLC、MS等结构确证图谱;详情请点 用户名 ,谢谢! 专业<杂质对照品>解决方案,代理中检所/EP/BP/USP/LGC/TRC/DR/TLC/MC/SIGMA/BACHEM/STD等品牌。
FINASTERIDE非那雄胺台湾用药说明
FINASTERIDE非那雄胺<<商品名>>台灣健保藥品 -P r o l e a k威福錠,P r o s t e r i d e艾舒得膜衣錠, T e n s e n健列腺膜衣錠, F i n t a快得膜衣錠, K i n s c a r景斯可膜衣錠,F i n a s p r o法健達膜衣錠 ,F i n a r i d e法路寧膜衣錠,P r o s c a r波斯卡錠,P r u f i l m流普適膜衣錠,F y n a s i d菲那諾膜衣錠,F i n a s t a t e護攝舒膜衣錠.美國- P r o p e c i a;P r o s c a r加拿大 -C O F i n a s t e r i d e;J A M P-F i n a s t e r i d e;M y l a n-F i n a s t e r i d e;N o v o-F i n a s t e r i d e; P M S-F i n a s t e r i d e;P r o p e c i a;P r o s c a r;r a t i o-F i n a s t e r i d e;S a n d o z-F i n a s t e r i d eF i n a s(新加坡);F i n a s t(新加坡);F i n c a r(香港,印度,);P r o p e c i a(阿根廷,澳大利亞,巴西,智利,西班牙,香港,以色列,馬來西亞,荷蘭,紐西蘭,巴拿馬 ,秘魯,菲律賓,瑞典,新加坡,薩爾瓦多,泰國);P r o s c a r(阿根廷,奧地利,澳大利亞,比利時,玻利維亞,巴西,瑞士,智利,德國,丹麥,西班牙,芬蘭,希臘,香港,印尼,愛爾蘭,義大利,盧森堡,馬爾他,墨西哥,馬來西亞,挪威,紐西蘭,巴拿馬 ,秘魯,菲律賓,巴基斯坦,波蘭,葡萄牙,俄羅斯,瑞典,新加坡,斯洛伐克,泰國,土耳其,委內瑞拉)<<藥物作用>>本藥為一種「控制前列腺腫大」的藥物。
安全数据表(SDS)单号:1796009-ENG-06,发布日期:1998年2月18日,修订日期:2
Safety Data SheetDocument number First issued Revised date Revision Issued by Page 1796009-ENG-06 1998-02-18 2008-01-29 5 Jeanette Hasseson 1 of 4Alpacon 0091. Identification of the substance/preparation and of the company/undertakingTrade Name: Supplier:Alpacon 009 ALFA LAVAL ABHans Stahles vägProduct Type: S-147 80 TumbaEmulsion breaker SwedenTel: +46 8 530 650 00e-mail:Emergency number: +46 8 33 70 43 open 24 h2. Hazard identificationThe surfactant might cause serious damage to eyes and may cause long-term adverse effects in the aquatic environmentIf the product is used as recommended the surfactants will be soluble in oil and therefore they will be excluded in the water- phase.3. Composition/information on the ingredientsHazardous ingredients Weight-% CAS No ECNoClassification Risk PhrasesPolymer 5 – 15 - - NoneSurfactants 5 – 10 68989-03-7 - Xi, N R41, 51/53 See section 16 for explanations to R-phrases.4. First –aid measuresFirst aid – Inhalation Move to fresh air.First aid – Skin contact Wash off with plenty of water.First aid – Eye contact Rinse immediately with tepid water for several minutes. Proceedthe rinse during transport to hospital.Obtain medical attention.First aid – Ingestion Rinse mouth and drink at least 1-2 glasses of water. Do notinduce vomiting.Obtain medical attention.5. Fire- fighting measuresExtinguishing media All extinguishing media are suitable.Special hazards of product The product is not flammable. In case of fire the product mightform hazardous gases as NOx and COx.Protective equipment for fire fighting Not applicable.Fire –fight If the fire is extinguished with water environmental dangeroussubstances might be entering the environment.6. Accidental release measuresPersonal precautions Wear suitable goggles and gloves.Environmental precautions Prevent spills from reaching sewage, wells and watercourses. Spillage Absorb spills with sand, earth or other inert material. Collect andremove for destruction.Large spillage Contact local authority7. Handling and storageHandling Do not mix with other chemicals. Use recommended personalprotection according to section 8.Storage Store in a closed container.8. Exposure control / personal protectionRespiratory protection Appropriate ventilation. Provide facilities for rinsing eyes.Skin protection Protective gloves of nitrile.Eye protection Safety goggles.Ingestion Do not eat or drink during use. Wash hands before eating.9. Physical and chemical propertiesPhysical state Clear liquid.Colour Slightly yellow.Odour Weak smell.Density at 20 °C (g/ml) 1.025± 0.005.pH (as is) at 20 °C 7-9°brix 17.8±0.6.Viscosity at 25 °C (SP01/20 rpm) (cP) 1368±130.Cloud point during heating (°C) 50ºC.Flash point >100 º C10. Stability and reactivityStability The product is stable under normal conditions, but it decomposesat high temperatures.Conditions to avoid Extreme heatMaterials to avoid None knownHazardous decomposition products None known if the product is handled as recommended. In caseof fire the product might form hazardous gases as NOx and COx.11. Toxicological informationSkin At prolonged or frequently use of the product blush might occur.Eyes The product might cause serious damage to eyes.Consumption Low acute toxicity . Might be irritating to mucous membrane.LD50 oral rat 4500mg/kgSkin irritation test rabbit Slightly irritatingEye irritation test rabbit Strongly irritatingSensibillisation Not allergenicGen toxicity Not mutagenic12. Ecological informationLC50 96h (fish) >100mg/lNOEC 96 h (fish) > 100mg/lEC50 48h (Daphnia magna) > 100mg/lNOEC 48 h (Daphnia magna) > 100 mg/lDegradation No readily bodegradable13. Disposal considerationsDisposal of product: State and local disposal regulations may differ from federaldisposal regulations. Always dispose in accordance with federal,state and local requirements.Disposal of containers: Containers should be reused or disposed of by landfill orincineration as appropriate.14. Transport informationNot classified as a hazardous substance according to transport regulations.15. Regulatory informationLabel Symbol(s): XiIrritantRisk Phrases: R36 Irritating to eyes.R52/53 Harmful to aquatic organisms, may cause long-termadverse effects in the aquatic environment.Safety Phrases: S39 Wear eye/ face protection.16. Other informationExplanations to R-phrases in section 2 R41 Risk of serious damage to eyes.R51/53 Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.See also product label for product applications.Important changes have been made in section: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 and 15.DISCLAIM OF RESPONSIBILITYAlfa Laval provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is only a guide to the potential hazards of the product. All individuals working with or around the product should be properly trained. Persons coming into contact with the product must be capable of exercising their own independent judgment concerning the conditions or methods of handling, storage and usage of the product. Alfa Laval will not be responsible for claims, losses, or damages of any kind resulting from the information provided in this Safety Data Sheet or the use, handling, storage or disposal of the product. Alfa Laval makes no representations or warranties, either express or implied, including without limitation any warranties of merchantability or fitness for a particular purpose with respect to the information set out herein or the product to which the information refers.。
梯希爱(上海)化成工业发展有限公司乙基甾烯二酮商品说明书
*This SDS for user in China - Not correspond to the regulation of other regions.梯希爱(上海)化成工业发展有限公司修订日期修订日期:: 08/08/2021化学品安全技术说明书修改号码修改号码:: 2.1修订日期修订日期:: 08/08/2021Page 1 of 32. 危险性概述G H S 分类物理性危害未分类 健康危害未分类 环境危害未分类 G H S 标签元素图标或危害标志无 信号词无信号词 危险描述无 防范说明无1. 化学品及企业标识产品名称产品名称::乙基甾烯二酮T C I 产品编码产品编码::E0921公司:梯希爱(上海)化成工业发展有限公司地址:上海化学工业区普工路96号部门:营业部电话号码:************传真号码:************e-mail:*************************应急电话应急电话::*************修改号码修改号码::2.13. 成分/组成信息单一物质/混合物单一物质化学名(中文名):乙基甾烯二酮百分比百分比::>98.0%(HPLC)CAS RN :21800-83-9俗名俗名::18-Methylestr-4-en-3,17-dione 分子式分子式::C 19H 26O 24. 急救措施吸入吸入::将受害者移到新鲜空气处,保持呼吸通畅,休息。
若感不适请求医/就诊。
皮肤接触皮肤接触::立即去除/脱掉所有被污染的衣物。
用水清洗皮肤/淋浴。
若皮肤刺激或发生皮疹:求医/就诊。
眼睛接触眼睛接触::用水小心清洗几分钟。
如果方便,易操作,摘除隐形眼镜。
继续清洗。
如果眼睛刺激:求医/就诊。
食入食入::若感不适,求医/就诊。
漱口。
紧急救助者的防护紧急救助者的防护::救援者需要穿戴个人防护用品,比如橡胶手套和气密性护目镜。
梯希爱(上海)化成工业发展有限公司修改号码修改号码:: 2.1修订日期修订日期::08/08/2021Page 2 of 3 5.消防措施合适的灭火剂合适的灭火剂::干粉,泡沫,雾状水,二氧化碳特定方法特定方法::从上风处灭火,根据周围环境选择合适的灭火方法。
吉非罗齐
孕妇及哺乳期妇女用药
在动物中大剂量使用本品可致胎仔死亡,人体研究未有报道。本品是否进入乳汁不详,故孕妇及哺乳期妇女 不宜服用本品。
儿童用药
儿童服用本品的研究尚不充分,应用时须权衡利弊。
老年患者用药
老年人如有肾功能不良时,须适当减少本品用药量。
药物相互作用
1、可明显增强口服抗凝药的作用,与其同用时应注意降低口服抗凝药的剂量,经常监测凝血酶原时间以调 整抗凝药剂量。其作用机理尚不确定,可能是因为本品能将华法林等从其蛋白结合位点上替换出来,从而使其作 用加强。
药物过量
目前尚无有关本品药物过量的报道,如发生药物过量,应针对中毒症状采取相应支持疗法。
药典信息
基本信息 性状
鉴别 检查
含量测定 类别
贮藏 制剂
基本信息
本品为2,2-二甲基-5-(2,5-二甲苯基氧基)-戊酸,按无水物计算,含C15H22O3应为98.0% ~102.0%。
性状
本品为白色结晶性粉末,无臭。 本品在三氯甲烷中极易溶解,在甲醇、乙醇、丙酮或己烷中易溶,在水中不溶,在氢氧化钠试液中易溶。 熔点 本品的熔点(通则0612)为58~61°C。
4、与胆汁酸结合树脂,如考来替泊等合用,则至少应在服用这些药物之前2小时或2小时之后再服用吉非罗 齐。因胆汁酸结合药物可结合同时服用的其它药物,进而影响其它药的吸收。
5、主要经肾排泄,在与免疫抑制剂,如环孢素合用时,可增加后者的血药浓度和肾毒性,有导致肾功能恶 化的危险,应减量或停药。本品与其它有肾毒性的药物合用时也应0512)测定。 供试品溶液:取本品,加流动相溶解并稀释制成每1mL中约含10mg的溶液。 对照溶液:精密量取供试品溶液适量,用流动相定量稀释制成每1mL中约含20µg的溶液。 系统适用性溶液:取吉非罗齐对照品与杂质Ⅰ适量,加流动相溶解并稀释制成每1mL中分别约含0.2mg和 0.05mg的溶液。 色谱条件:用十八烷基硅烷键合硅胶为填充剂,以甲醇-水-冰醋酸(75:24:1)为流动相,检测波长为 276nm,进样体积10μL。 系统适用性要求:系统适用性溶液色谱图中,吉非罗齐峰与杂质Ⅰ峰的分离度应符合要求,理论板数按吉非 罗齐峰计算不低于1500。 测定法:精密量取供试品溶液与对照溶液,分别注入液相色谱仪,记录色谱图至主成分峰保留时间的2倍。 限度:供试品溶液色谱图中如有杂质峰,单个杂质峰面积不得大于对照溶液的主峰面积(0.
米非司酮
药物相互作用
不能与利福平、卡马西平、灰黄霉素、巴比妥类、苯妥英钠、非甾体抗炎药、阿司匹林、肾上腺皮质激素并 用。
安全信息
安全术语
风险术语
安全术语
S22:Do not breathe dust. 不要吸入粉尘。 S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 穿戴适当的防护服、手套和眼睛/面保护。 S45:In case of accident or if you feel unwell, seek medical advice immediately (show the lable where possible). 发生事故时或感觉不适时,立即求医(可能时出示标签)。 S53:Avoid exposure - obtain special instructions before use. 避免接触,使用前获得特别指示说明。
化合物简介
基本信息 理化性质
计算化学数据 用途
基本信息
化学式:C29H35NO2 分子量:429.594 CAS号:-65-3
理化性质
密度:1.18g/cm3 熔点:195-198°C 沸 点 : 6 2 8 . 6 ºC 闪 点 : 3 3 4 ºC 折射率:1.623 外观:淡黄色结晶性粉末 溶解性:在甲醇或二氯甲烷中易溶,在乙醇或乙酸乙酯中溶解,在水中几乎不溶
鉴别
1、取本品,加乙醇溶解并稀释制成每1mL中约含10μg的溶液,照紫外-可见分光光度法(通则0401)测定, 在304nm与260nm的波长处有最大吸收。
2、本品的红外光吸收图谱应与对照的图谱(光谱集1141图)一致。