油酸二乙醇酰胺结构式

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油酸二乙醇酰胺结构式
英文回答:
Oleoylethanolamide is an endogenous lipid mediator that has been found to have a variety of physiological effects, including reducing food intake, body weight, and inflammation. It is structurally similar to the endocannabinoid anandamide, but it does not bind to cannabinoid receptors. Oleoylethanolamide is produced in the small intestine and other tissues in response to food intake. It is thought to act by binding to the peroxisome proliferator-activated receptor alpha (PPARα), which is a nuclear receptor that regulates gene expression.
The structure of oleoylethanolamide is as follows:
CH3(CH2)7CH=CH(CH2)7COOCH2CH2NH2。

中文回答:
油酸二乙醇酰胺是一种内源性脂质介质,已被发现具有多种生理效应,包括减少食物摄入、体重和炎症。

它的结构与内源性大麻素阿南酰胺相似,但它不与大麻素受体结合。

油酸二乙醇酰胺在小肠和其他组织中产生,以响应食物摄入。

它被认为通过与过氧化物酶体增殖物激活受体α(PPARα)结合而起作用,PPARα是一种调节基因表达的核受体。

油酸二乙醇酰胺的结构如下:
CH3(CH2)7CH=CH(CH2)7COOCH2CH2NH2。

补充信息:
Oleoylethanolamide is a promising target for the treatment of obesity and related metabolic disorders.
It has been shown to reduce food intake and body weight in animal models.
It is also thought to have anti-inflammatory and anti-diabetic effects.
Further research is needed to confirm the efficacy and safety of oleoylethanolamide for the treatment of human diseases.
油酸二乙醇酰胺是治疗肥胖症和相关代谢紊乱的一个有前景的靶点。

它已被证明可以减少动物模型中的食物摄入和体重。

它还被认为具有抗炎和抗糖尿病的作用。

需要进一步的研究来证实油酸二乙醇酰胺在治疗人类疾病方面的疗效和安全性。

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