先天性心脏病患儿手术前后血BNP的变化及临床意义

先天性心脏病患儿手术前后血BNP的变化及临床意义
王小威
【期刊名称】《中国医学创新》
【年(卷),期】2014(11)36
【摘要】Objective:To analysis and compare the changes and clinical significance of children with congenital heart disease before and after operation serum BNP.Method:60 cases of children with congenital heart disease in our hospital from January 2013 to August 2014 were selected to study,and were divided into control group and observation group. 30 cases of simple congenital heart disease patients were selected as the control subjects.30 patients with severe congenital heart disease in children of experimental group were selected as research object.Changes of blood BNP before and after operation of the two groups of children were comparative analysised, significance of BNP in the critically ill children with congenital heart disease in evaluation of cardiac function after operation was analysised.Result:The serum level of BNP before and after the experimental group of children with congenital heart disease operation was (19.0±9.9)ng/L,5 min after operation was (23±14)ng/L,24 h after the operation was (32±11)ng/L,compared with the control group, the differences were statistically significant(P<0.05).Conclusion:It can draw the internal connection between the level of BNP in serum and the corresponding level of heart function through the study of changes of
blood BNP before and after operation in children with congenital heart disease in clinic.Find an accurate, quick method to understand the level of heart function is help to safeguard the health of patients,it is worthy to be popularized in practice.%目的：分析比较先天性心脏病患儿手术前后血BNP的变化及临床意义。

方法：对本院从2013年1月-2014年8月收治的60例先天性心脏病患儿进行研究，30例简单先天性心脏病患儿作为对照组，30例危重症先天性心脏病患儿作为试验组，对比分析两组患儿在手术前后血BNP变化，分析BNP 在危重症先心病患儿术后心功能评定中的意义。

结果：试验组先天性心脏病患儿手术前血BNP水平为（19.0±9.9）ng/L，术后5 min为（23±14）ng/L，术后24 h为（32±11）ng/L，较对照组差异有统计学意义（P<0.05）。

结论：在临床中通过研究先天性心脏病患儿手术前后血BNP变化，可以得出血清BNP水平与相应心功能水平之间的内在联系，找到一种准确、快速了解心功能水平的方法，有助于保障患者的健康，值得在实际中推广。

【总页数】4页(P54-56,57)
【作者】王小威
【作者单位】江西省儿童医院江西南昌 330006
【正文语种】中文
【相关文献】
1.高原地区先天性心脏病患儿血浆BNP检测的临床意义 [J], 王红练;阿祥仁
2.动态监测血乳酸对先天性心脏病心内直视手术患儿的临床意义 [J], 李瑞兰;任晓莉
3.先天性心脏病患儿手术前后血内皮素-1和一氧化氮的浓度变化 [J], 孔霞;项如莲;温怀凯;胡型锑;杨雪静
4.先天性心脏病合并心力衰竭患儿血浆BNP水平临床意义探讨 [J], 洪炼哲;阳明玉;钟涛;李雄
5.先天性心脏病患儿手术过程中血清心肌钙蛋白I的变化及临床意义 [J], 张洪涛;张荣梅;徐洪军;罗泽伟
因版权原因，仅展示原文概要，查看原文内容请购买。