环磷腺苷葡胺配伍丹红注射液治疗冠心病患者的效果

病患者颈动脉斑块积分葡胺；丹红注射液；心绞痛
中图分类号：R541.4
文献标志码：A
文章编号：2096-1413(2020)03-0031-02
Effect of meglumine adenosine cyclophosphate combined with Danhong injection on patients with coronary heart disease
础上给予环磷腺苷葡注射液治疗。比较两组患者治疗前、后的 IMT、颈动脉斑块积分、心绞痛发生率和发作频度。结果 治疗后，
研究组 IMT、颈动脉斑块积分低于对照组（P约0.05）。研究组心绞痛发生率为 24.14%，低于对照组的 56.14%（P约0.05）；治疗后，研
究组心绞痛发作次数、每次发作的持续时间均显著优于对照组（P约0.05）。结论 环磷腺苷葡胺配伍丹红注射液明显改善了冠心
2020 年 1 月
临床医学
环磷腺苷葡胺配伍丹红注射液治疗冠心病患者的效果
王 飞 燕 ，任 牧 * （碑林区中医医院，陕西 西安，710000）
摘要：目的 观察环磷腺苷葡胺配伍丹红注射液治疗冠心病的效果。方法 选取 2018 年 1 月至 2019 年 1 月我院收治的 115 例冠
心病患者作为研究对象，根据不同治疗方式将其分成对照组（57 例）和研究组（58 例）。对照组予以丹红注射液，研究组在此基
1 资料与方法
1.1 一般资料 选取 2018 年 1 月至 2019 年 1 月本院内科门诊收治的
115 例冠心病患者作为研究对象，根据不同治疗方式将其分成 对照组（57 例）和研究组（58 例）。对照组男女构成比为 32颐25； 年龄 45~80 岁，平均（65.25依5.24）岁；病程 1~7 年，平均（3.22依
心绞痛是冠心病常见表现[1]，是因冠状动脉供血不足，导 致心肌急剧发生的缺氧、缺血，心脏供血、需求失衡，进而引起 胸闷、胸痛、活动受限、晕厥等一系列临床不适，严重时可能导 致心肌梗死、猝死等。西医临床采用药物、手术等治疗该症取 得了一定效果，但术后有再次狭窄的风险。环磷腺苷葡胺属于 非强心甙类强心药，能够调节心肌功能。丹红注射液对冠心病 的胸痛、心悸、胸闷等症状具有显著效果，二者联合治疗冠心 病的效果获得了广泛认可[2]。目前，联合用药治疗冠心病主要 针对疗效、症状等研究，本研究特分析了其对患者动脉硬化斑 块的影响，现报道如下。
WANG Fei-yan, REN Mu * (Traditional Chinese Medicine Hospital of Beilin District, Xi'an 710000, China)
ABSTRACT: Objective To observe the effect of meglumine adenosine cyclophosphate combined with Danhong injection in the treatment of coronary heart disease. Methods A total of 115 patients with coronary heart disease admitted in our hospital from January 2018 to January 2019 were selected as the research objects and divided into control group (57 cases) and study group (58 cases) according to different treatment methods. The control group was treated with Danhong injection, and the study group was treated with meglumine adenosine cyclophosphate injection on this basis. IMT, carotid plaque score, incidence and frequency of angina pectoris before and after treatment were compared between the two groups. Results After treatment, IMT and carotid plaque score in the study group were lower than those in the control group (P<0.05). The incidence of angina pectoris in the study group was 24.14%, which was lower than 56.14% in the control group (P<0.05); after treatment, the number of angina pectoris attack and the duration of each attack in the study group were significantly better than those in the control group (P <0.05). Conclusion Meglumine adenosine cyclophosphate combined with Danhong injection can significantly improve carotid plaque score, IMT and the frequency of angina pectoris attacks in patients with coronary heart disease. KEYWORDS: coronary heart disease; meglumine adenosine cyclophosphate; Danhong injection; angina pectoris