Capadenoson_544417-40-5_DataSheet_MedChemExpress
防晒剂大全
防晒剂大全Octinoxate也标识为Octylmethoxy Cinnamate、Octyl Methoxycinnamate、Parsol MCX、Escalol 557、Ethylhexyl methoxycinnamate、2-Ethylhexyl 4-methoxycinnamate、2-Ethylhexyl-p-methoxycinnamate。
中文名曰：桂皮酸盐，也叫甲氧基肉桂酸辛酯、4-甲氧基肉桂酸-2-乙基己基酯、2-羟基-4-甲氧基二苯甲酮。
Octinoxate是目前全世界范围内最广泛使用的紫外线UVB防晒剂，属于油性化学防晒剂，可以吸收UVB 290～320波段，对皮肤的刺激性小，但在动物试验中观察到其对雌激素有所影响，浓度限量10%。
Parsol 1789也标识为Avobenzone、Eusolex 9020、Avobenzene、Butyl Methoxydibenzoylmethane、Avobezone。
中文名曰：帕索1789，也叫丁基甲氧基二苯甲酰基甲烷。
Parsol 1789是一种主要的紫外线UVA防晒剂，属于化学防晒剂，可以吸收UVA 320～400波段，可以阻隔一些UVA-I，但对于UVA-II效果微弱，因此常与Benzophenone-3（二苯加酮-3）混合使用，易引发过敏等皮肤不适。
此外，Parsol 1789的主要缺点是光稳定性不高，经过紫外线的照射后会渐渐被分解而失去防晒效果，特别是跟某些防晒成分如Octinoxate放在一起，会更加不稳定更易被光分解。
Ensulizole也标识为2-phenylbenzimidazole-5-sulfonic Acid、Phenylbenzimidazole Sulfonic Acid。
中文名曰：苯基苯丙咪唑磺酸。
Ensulizole是一种紫外线UVB防晒剂，也能吸收很小部分的UVA波段，属于水溶性化学防晒剂，缺点是曝露于阳光下会产生自由基，从而损伤皮肤DNA，严重时有致癌的可能。
AT28HC64B高性能电擦可编程只读存储器（EEPROM）说明书
Features Array•Fast Read Access Time – 70 ns•Automatic Page Write Operation–Internal Address and Data Latches for 64 Bytes•Fast Write Cycle Times–Page Write Cycle Time: 10 ms Maximum (Standard)2 ms Maximum (Option – Ref. AT28HC64BF Datasheet)–1 to 64-byte Page Write Operation•Low Power Dissipation–40 mA Active Current–100µA CMOS Standby Current•Hardware and Software Data Protection•DATA Polling and Toggle Bit for End of Write Detection•High Reliability CMOS Technology–Endurance: 100,000 Cycles–Data Retention: 10 Years•Single 5 V ±10% Supply•CMOS and TTL Compatible Inputs and Outputs•JEDEC Approved Byte-wide Pinout•Industrial Temperature Ranges•Green (Pb/Halide-free) Packaging Option Only1.DescriptionThe AT28HC64B is a high-performance electrically-erasable and programmable read-only memory (EEPROM). Its 64K of memory is organized as 8,192 words by 8 bits. Manufactured with Atmel’s advanced nonvolatile CMOS technology, the device offers access times to 55 ns with power dissipation of just 220 mW. When the device is deselected, the CMOS standby current is less than 100µA.The AT28HC64B is accessed like a Static RAM for the read or write cycle without the need for external components. The device contains a 64-byte page register to allow writing of up to 64 bytes simultaneously. During a write cycle, the addresses and 1 to 64 bytes of data are internally latched, freeing the address and data bus for other operations. Following the initiation of a write cycle, the device will automatically write the latched data using an internal control timer. The end of a write cycle can be detected by DATA polling of I/O7. Once the end of a write cycle has been detected, a new access for a read or write can begin.Atmel’s AT28HC64B has additional features to ensure high quality and manufactura-bility. The device utilizes internal error correction for extended endurance and improved data retention characteristics. An optional software data protection mecha-nism is available to guard against inadvertent writes. The device also includes anextra 64 bytes of EEPROM for device identification or tracking.20274L–PEEPR–2/3/09AT28HC64B2.Pin Configurations2.128-lead SOIC Top ViewPin Name Function A0 - A12Addresses CE Chip Enable OE Output Enable WE Write Enable I/O0 - I/O7Data Inputs/Outputs NC No Connect DCDon’t Connect2.232-lead PLCC Top ViewNote:PLCC package pins 1 and 17 are Don’t Connect.2.328-lead TSOP Top View30274L–PEEPR–2/3/09AT28HC64B3.Block Diagram4.Device Operation4.1ReadThe AT28HC64B is accessed like a Static RAM. When CE and OE are low and WE is high, the data stored at the memory location determined by the address pins is asserted on the out-puts. The outputs are put in the high-impedance state when either CE or OE is high. This dual line control gives designers flexibility in preventing bus contention in their systems.4.2Byte WriteA low pulse on the WE or CE input with CE or WE low (respectively) and OE high initiates a write cycle. The address is latched on the falling edge of CE or WE, whichever occurs last. The data is latched by the first rising edge of CE or WE. Once a byte write has been started, it will automatically time itself to completion. Once a programming operation has been initiated and for the duration of t WC , a read operation will effectively be a polling operation.4.3Page WriteThe page write operation of the AT28HC64B allows 1 to 64 bytes of data to be written into the device during a single internal programming period. A page write operation is initiated in the same manner as a byte write; after the first byte is written, it can then be followed by 1 to 63 additional bytes. Each successive byte must be loaded within 150 µs (t BLC ) of the previous byte. If the t BLC limit is exceeded, the AT28HC64B will cease accepting data and commence the internal programming operation. All bytes during a page write operation must reside on the same page as defined by the state of the A6 to A12 inputs. For each WE high-to-low transition during the page write operation, A6 to A12 must be the same.The A0 to A5 inputs specify which bytes within the page are to be written. The bytes may be loaded in any order and may be altered within the same load period. Only bytes which are specified for writing will be written; unnecessary cycling of other bytes within the page does not occur.4.4DATA PollingThe AT28HC64B features DATA Polling to indicate the end of a write cycle. During a byte or page write cycle, an attempted read of the last byte written will result in the complement of the written data to be presented on I/O7. Once the write cycle has been completed, true data is valid on all outputs, and the next write cycle may begin. DATA Polling may begin at any time during the write cycle.40274L–PEEPR–2/3/09AT28HC64B4.5Toggle BitIn addition to DATA Polling, the AT28HC64B provides another method for determining the end of a write cycle. During the write operation, successive attempts to read data from the device will result in I/O6 toggling between one and zero. Once the write has completed, I/O6 will stop toggling, and valid data will be read. Toggle bit reading may begin at any time during the write cycle.4.6Data ProtectionIf precautions are not taken, inadvertent writes may occur during transitions of the host system power supply. Atmel ® has incorporated both hardware and software features that will protect the memory against inadvertent writes.4.6.1Hardware ProtectionHardware features protect against inadvertent writes to the AT28HC64B in the following ways: (a) V CC sense – if V CC is below 3.8 V (typical), the write function is inhibited; (b) V CC power-on delay – once V CC has reached 3.8 V, the device will automatically time out 5 ms (typical) before allowing a write; (c) write inhibit – holding any one of OE low, CE high or WE high inhib-its write cycles; and (d) noise filter – pulses of less than 15 ns (typical) on the WE or CE inputs will not initiate a write cycle.4.6.2Software Data ProtectionA software-controlled data protection feature has been implemented on the AT28HC64B. When enabled, the software data protection (SDP), will prevent inadvertent writes. The SDP feature may be enabled or disabled by the user; the AT28HC64B is shipped from Atmel with SDP disabled.SDP is enabled by the user issuing a series of three write commands in which three specific bytes of data are written to three specific addresses (refer to the “Software Data Protection Algorithm” diagram on page 10). After writing the 3-byte command sequence and waiting t WC , the entire AT28HC64B will be protected against inadvertent writes. It should be noted that even after SDP is enabled, the user may still perform a byte or page write to the AT28HC64B. This is done by preceding the data to be written by the same 3-byte command sequence used to enable SDP.Once set, SDP remains active unless the disable command sequence is issued. Power transi-tions do not disable SDP, and SDP protects the AT28HC64B during power-up and power-down conditions. All command sequences must conform to the page write timing specifica-tions. The data in the enable and disable command sequences is not actually written into the device; their addresses may still be written with user data in either a byte or page write operation.After setting SDP, any attempt to write to the device without the 3-byte command sequence will start the internal write timers. No data will be written to the device, however. For the dura-tion of t WC , read operations will effectively be polling operations.4.7Device IdentificationAn extra 64 bytes of EEPROM memory are available to the user for device identification. By raising A9 to 12 V ±0.5 V and using address locations 1FC0H to 1FFFH, the additional bytes may be written to or read from in the same manner as the regular memory array.50274L–PEEPR–2/3/09AT28HC64BNotes:1.X can be VIL or VIH.2.See “AC Write Waveforms” on page 8.3.VH = 12.0 V ±0.5 V.Note:1.I SB1 and I SB2 for the 55 ns part is 40 mA maximum.5.DC and AC Operating RangeAT28HC64B-70AT28HC64B-90AT28HC64B-120Operating Temperature (Case)-40°C - 85°C -40°C - 85°C -40°C - 85°C V CC Power Supply5 V ±10%5 V ±10%5 V ±10%6.Operating ModesMode CE OE WE I/O Read V IL V IL V IH D OUT Write (2)V IL V IH V IL D IN Standby/Write Inhibit V IH X (1)X High ZWrite Inhibit X X V IH Write Inhibit X V IL X Output Disable X V IH XHigh ZChip Erase V ILV H (3)V IL High Z7.Absolute Maximum Ratings*Temperature Under Bias................................-55°C to +125°C *NOTICE:Stresses beyond those listed under “Absolute Maximum Ratings” may cause permanent dam-age to the device. This is a stress rating only and functional operation of the device at these or any other conditions beyond those indicated in the operational sections of this specification is not implied. Exposure to absolute maximum rating conditions for extended periods may affect device reliabilityStorage Temperature.....................................-65°C to +150°C All Input Voltages(including NC Pins)with Respect to Ground.................................-0.6 V to +6.25 V All Output Voltageswith Respect to Ground...........................-0.6 V to V CC + 0.6 V Voltage on OE and A9with Respect to Ground..................................-0.6 V to +13.5V8.DC CharacteristicsSymbol Parameter ConditionMinMax Units I LI Input Load Current V IN = 0 V to V CC + 1 V 10µA I LO Output Leakage Current V I/O = 0 V to V CC10µA I SB1V CC Standby Current CMOS CE = V CC - 0.3 V to V CC + 1 V 100(1)µA I SB2V CC Standby Current TTL CE = 2.0 V to V CC + 1 V 2(1)mA I CC V CC Active Current f = 5 MHz; I OUT = 0 mA40mA V IL Input Low Voltage 0.8V V IH Input High Voltage 2.0V V OL Output Low Voltage I OL = 2.1 mA 0.40V V OH Output High VoltageI OH = -400 µA2.4V60274L–PEEPR–2/3/09AT28HC64B10.AC Read Waveforms (1)(2)(3)(4)Notes:1.CE may be delayed up to t ACC - t CE after the address transition without impact on t ACC .2.OE may be delayed up to t CE - t OE after the falling edge of CE without impact on t CE or by t ACC - t OE after an address changewithout impact on t ACC .3.t DF is specified from OE or CE whichever occurs first (C L = 5 pF).4.This parameter is characterized and is not 100% tested.9.AC Read CharacteristicsSymbol ParameterAT28HC64B-70AT28HC64B-90AT28HC64B-120Units MinMax MinMax MinMax t ACC Address to Output Delay 7090120ns t CE (1)CE to Output Delay 7090120ns t OE (2)OE to Output Delay 035040050ns t DF (3)(4)OE to Output Float 035040050ns t OHOutput Hold00ns70274L–PEEPR–2/3/09AT28HC64B11.Input Test Waveforms and Measurement Level12.Output Test LoadNote:1.This parameter is characterized and is not 100% tested.R F 13.Pin Capacitancef = 1 MHz, T = 25°C (1)Symbol Typ Max Units Conditions C IN 46pF V IN = 0 V C OUT 812pFV OUT = 0 V815.AC Write Waveforms15.1WE Controlled15.2CE Controlled14.AC Write CharacteristicsSymbol ParameterMin MaxUnits t AS , t OES Address, OE Setup Time 0ns t AH Address Hold Time 50ns t CS Chip Select Setup Time 0ns t CH Chip Select Hold Time 0ns t WP Write Pulse Width (WE or CE)100ns t DS Data Setup Time 50ns t DH , t OEHData, OE Hold Timens90274L–PEEPR–2/3/09AT28HC64B17.Page Mode Write Waveforms (1)(2)Notes: 1.A6 through A12 must specify the same page address during each high to low transition of WE (or CE).2.OE must be high only when WE and CE are both low.18.Chip Erase Waveformst S = t H = 5 µs (min.)t W = 10 ms (min.)V H = 12.0 V ±0.5 V16.Page Mode CharacteristicsSymbol Parameter MinMax Units t WC Write Cycle Time10ms t WC Write Cycle Time (Use AT28HC64BF))2ms t AS Address Setup Time 0ns t AH Address Hold Time 50ns t DS Data Setup Time 50ns t DH Data Hold Time 0ns t WP Write Pulse Width 100ns t BLC Byte Load Cycle Time 150µs t WPHWrite Pulse Width High50ns100274L–PEEPR–2/3/09AT28HC64B19.Software Data Protection EnableAlgorithm (1)Notes:1.Data Format: I/O7 - I/O0 (Hex);Address Format: A12 - A0 (Hex).2.Write Protect state will be activated at end of writeeven if no other data is loaded.3.Write Protect state will be deactivated at end of writeperiod even if no other data is loaded.4.1 to 64 bytes of data are loaded.20.Software Data Protection DisableAlgorithm (1)Notes:1.Data Format: I/O7 - I/O0 (Hex);Address Format: A12 - A0 (Hex).2.Write Protect state will be activated at end of writeeven if no other data is loaded.3.Write Protect state will be deactivated at end of writeperiod even if no other data is loaded.4. 1 to 64 bytes of data are loaded.21.Software Protected Write Cycle Waveforms (1)(2)Notes:1.A6 through A12 must specify the same page address during each high to low transition of WE (or CE) after the softwarecode has been entered.2.OE must be high only when WE and CE are both low.11AT28HC64BNote:1.These parameters are characterized and not 100% tested. See “AC Read Characteristics” on page 6.23.Data Polling WaveformsNotes:1.These parameters are characterized and not 100% tested.2.See “AC Read Characteristics” on page 6.25.Toggle Bit Waveforms (1)(2)(3)Notes: 1.Toggling either OE or CE or both OE and CE will operate toggle bit.2.Beginning and ending state of I/O6 will vary.3.Any address location may be used, but the address should not vary.22.Data Polling Characteristics (1)Symbol Parameter Min TypMaxUnits t DH Data Hold Time 0ns t OEH OE Hold Time 0ns t OE OE to Output Delay (1)ns t WR Write Recovery Timens24.Toggle Bit Characteristics (1)Symbol Parameter Min TypMaxUnits t DH Data Hold Time 10ns t OEH OE Hold Time 10ns t OE OE to Output Delay (2)ns t OEHP OE High Pulse 150ns t WR Write Recovery Timens12AT28HC64B26.Normalized I CCGraphs13AT28HC64B27.Ordering Information27.1Green Package Option (Pb/Halide-free)t ACC (ns)I CC (mA)Ordering Code Package Operation RangeActive Standby 70400.1AT28HC64B-70TU 28T Industrial (-40°C to 85°C)AT28HC64B-70JU 32J AT28HC64B-70SU 28S 90400.1AT28HC64B-90JU 32J AT28HC64B-90SU 28S AT28HC64B-90TU 28T 120400.1AT28HC64B-12JU 32J AT28HC64B-12SU28SPackage Type32J 32-lead, Plastic J-leaded Chip Carrier (PLCC)28S 28-lead, 0.300" Wide, Plastic Gull Wing Small Outline (SOIC)28T28-lead, Plastic Thin Small Outline Package (TSOP)27.2Die ProductsContact Atmel Sales for die sales options.28.Packaging Information 28.132J – PLCC14AT28HC64BAT28HC64B 28.228S – SOIC1528.328T – TSOP16AT28HC64BHeadquarters InternationalAtmel Corporation 2325 Orchard Parkway San Jose, CA 95131 USATel: 1(408) 441-0311 Fax: 1(408) 487-2600Atmel AsiaUnit 1-5 & 16, 19/FBEA Tower, Millennium City 5418 Kwun Tong RoadKwun Tong, KowloonHong KongTel: (852) 2245-6100Fax: (852) 2722-1369Atmel EuropeLe Krebs8, Rue Jean-Pierre TimbaudBP 30978054 Saint-Quentin-en-Yvelines CedexFranceTel: (33) 1-30-60-70-00Fax: (33) 1-30-60-71-11Atmel Japan9F, Tonetsu Shinkawa Bldg.1-24-8 ShinkawaChuo-ku, Tokyo 104-0033JapanTel: (81) 3-3523-3551Fax: (81) 3-3523-7581Product ContactWeb SiteTechnical Support******************Sales Contact/contactsLiterature Requests/literatureDisclaimer: The information in this document is provided in connection with Atmel products. No license, express or implied, by estoppel or otherwise, to any intellectual property right is granted by this document or in connection with the sale of Atmel products. EXCEPT AS SET FORTH IN ATMEL’S TERMS AND CONDI-TIONS OF SALE LOCATED ON ATMEL’S WEB SITE, ATMEL ASSUMES NO LIABILITY WHATSOEVER AND DISCLAIMS ANY EXPRESS, IMPLIED OR STATUTORY WARRANTY RELATING TO ITS PRODUCTS INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTY OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE, OR NON-INFRINGEMENT. IN NO EVENT SHALL ATMEL BE LIABLE FOR ANY DIRECT, INDIRECT, CONSEQUENTIAL, PUNITIVE, SPECIAL OR INCIDEN-TAL DAMAGES (INCLUDING, WITHOUT LIMITATION, DAMAGES FOR LOSS OF PROFITS, BUSINESS INTERRUPTION, OR LOSS OF INFORMATION) ARISING OUT OF THE USE OR INABILITY TO USE THIS DOCUMENT, EVEN IF ATMEL HAS BEEN ADVISED OF THE POSSIBILITY OF SUCH DAMAGES. Atmel makes no representations or warranties with respect to the accuracy or completeness of the contents of this document and reserves the right to make changes to specifications and product descriptions at any time without notice. Atmel does not make any commitment to update the information contained herein. Unless specifically provided otherwise, Atmel products are not suitable for, and shall not be used in, automotive applications. Atmel’s products are not intended, authorized, or warranted for use as components in applications intended to support or sustain life.© 2009 Atmel Corporation. All rights reserved. Atmel®, logo and combinations thereof, and others are registered trademarks or trademarks of Atmel Corporation or its subsidiaries. Other terms and product names may be trademarks of others.。
Capadenoson_544417-40-5_DataSheet_MedChemExpress
Product Name:Capadenoson CAS No.:544417-40-5Product Data SheetCat. No.:HY-14917MWt:520.03Formula:C25H18ClN5O2S2Purity :>98%Solubility:Mechanisms:Biological Activity:Pathways:Others; Target:Adenosine Receptor DMSOg y Capadenoson (BAY 68-4986) is a new adenosine A1 receptor agonist. Studies showed that long-term therapy with Capadenoson improves phosphorylation and total protein level of PGC-1α in LV myocardium of HF dogs. Clinical trial found that in patients with stable angina Capadenoson lowers exercise HR at comparable maximum workload, which is associated with improved total exercise time and prolongation of time to ischaemia.References:[1]. Ramesh C. Gupta, Kristina Szekely, Mengjun Wang, et al. Long-term therapy with the partial adenosine A1-receptor agnosit capadenoson, improves peroxisome proliferator-activated receptor coactivator-1α phosphorylation and protein expression in left ventricular myocardium of dogs with chronic heart failure. J Am Coll Cardiol. 2013;61(10_S).(_)[2]. Tendera M, Gaszewska-?urek E, Parma Z, et al. The new oral adenosine A1 receptor agonistcapadenoson in male patients with stable angina. Clin Res Cardiol. 2012 Jul;101(7):585-91.[3]. Bott-Flügel L, Bernshausen A, Schneider H, et al. Selective attenuation of norepinephrinerelease and stress-induced heart rate increase by partial adenosine A1 agonism. PLoS One. 2011Mar 28;6(3):e18048.[4]. Müller CE, Jacobson KA. Recent developments in adenosine receptor ligands and their potential as novel drugs. Biochim Bio...Caution: Not fully tested. For research purposes onlyMedchemexpress LLC18W i l k i n s o n W a y , P r i n c e t o n , N J 08540,U S AE m a i l : i n f o @m e d c h e m e x p r e s s .c o m W e b : w w w .m e d c h e m e x p r e s s .c o m。
PANTHER Terminal de pesaje 说明书
PANTHER®Terminal de pesajeVelocidad y precisión en sus aplicaciones de pesaje y control de procesosAustralia (61-3) 9646 4551(61-3) 9645 3935Austria (43-1) 604 1980(43-1) 604 2880Belgium (32-2) 334 0211(32-2) 378 1665Brazil (55-11) 421 5737(55-11) 7295-1692Canada(905) 681-7011(905) 681-1511China (Industrial)(86-519) 6642040(86-519) 6641991China (Systems)(86-21) 6485-0435(86-21) 6485-3351Croatia(385-1) 660 3009(385-1) 660 2189*Czech Republic (420-2) 254962(420-2) 24247583Denmark (45-43) 27 08 00(45-43) 27 08 28France (33-1) 30 97 17 78(33-1) 30 97 16 00Germany (49-641) 50 70(49-641) 52951Hungary (36) 1257 7030(36) 1256 2175Italy (39-2) 333321 (39-2) 356-2973Japan (81-6) 949-5901(81-6) 949-5944Korea (82-2) 518-2004(82-2) 518-0813METTLER TOLEDOUnited States and Canada 1900 Polaris Parkway Columbus, Ohio 43240TEL.(800) 786-0038(614) 438-4511FAX (614) 438-4518Headquarters 8606 Greifensee SchweizTEL.(41-1) 944 22 11FAX (41-1) 944 30 60Malaysia (60-3) 703-2773(60-3) 703 8773Mexico (52-5) 547 5700(52-5) 541 2228Netherlands (31-344) 638363(31-344) 638390Norway (47-22) 30 44 90(47-22) 32 70 02Poland (48-22) 651 9232(48-22) 42 20 01Russia (7-095) 921 9211(7-095) 921 6353Singapore(65) 778 6779(65) 778 6639Slovak Republic (421-7) 525 2170(421-7) 525 2173Slovenia (38-6) 6123-57 64(38-6) 6127-4575*Spain (34-93) 223 7600(34-3) 223 0271Sweden (46-8) 702 50 00(46-8) 642 45 62Switzerland (41-1) 944 45 45(41-1) 944 45 10Taiwan (886-2) 579-5955(886-2) 579-5977Thailand(66-2) 719 6480(66-2) 719 6479United Kingdom(44-116) 235 7070(44-116) 236 6399*Call for fax.TELFAXTELFAXInternet Especificaciones sujetas a cambios sin aviso previo. ©1999 Mettler-Toledo, Inc.METTLER-TOLEDO ‚UltraRes ,DigiTOL ‚y Panther ‚ son marcas registradas de Mettler-Toledo, Inc.ENCOMPASS es una marca registrada de Rockwell Automation.Modbus Plus y Mod Connect son marcas registradas de AEG Schneider Automation.PROFIBUS es una marca registrada de PROFIDUS Snutzerorganisation.Impreso en EEUU 5M1199INSTRUMENTS IN1041.4E/0SEEl terminal PANTHER es compacto, fácil de manejar y permite ser conectado a básculas analógicas y de la línea DigiTOL ®. Robusto y versátil está disponible tanto en caja estanca de acero inoxidable con dispositivo orientable, que puede montarse sobre columna, pared o sobremesa, como en versión panelable.Conectividad en control de proceso –El terminal PANTHER puede integrarse en los sistema de control de proceso de varias maneras: Con salida analógica de 4÷20 mA. ó 0÷10 V,entradas/salidas discretas, y mediante redes locales RIO Allen Bradley, Modbus Plus ®y PROFIBUS ®.Multiuso – Seleccionando pesaje estándar, dosificación por peso o clasificación manual por peso.Puntos de corte – Incorpora dos puntos de corte y zona de cero, que facilitan la creación de circuitos híbridos de control de proceso y el control de dosificación y llenado.Filtro ajustable – El terminal PANTHER incluye el exclusivo sistema defiltrado y rechazador de vibraciones Trax DSP de METTLER-TOLEDO,ajustable para reducir al mínimo eltiempo de respuesta y obtener indicación de peso estable incluso cuando la báscula contiene un agitador o dispositivo mezclador.Uso en áreas explosivas – El terminal PANTHER, combinado con barreras Zener adecuadas, puede ser conectado a plataformas y otros sistemas con células de carga situadas en zonas clasificadas.•••••Para obtener más información contacte con la organización local de Mettler-Toledo, S.A.E.Prestaciones estándar:Reducido en tamaño pero con altas prestaciones el terminaldepesaje PANTHER ofrece unvalor sostenido.。
NanoString质量控制仪表板版本2.0.5说明书
Package‘NACHO’August7,2023Type PackageTitle NanoString Quality Control DashboardVersion2.0.5Description NanoString nCounter data are gene expression assayswhere there is no need for the use of enzymes or amplificationprotocols and work withfluorescent barcodes(Geiss et al.(2018)<doi:10.1038/nbt1385>).Each barcode is assigned amessenger-RNA/micro-RNA(mRNA/miRNA)which after bonding with itstarget can be counted.As a result each count of a specific barcoderepresents the presence of its target mRNA/miRNA.'NACHO'(NAnoStringquality Control dasHbOard)is able to analyse the exported NanoStringnCounter data and facilitates the user in performing a qualitycontrol.'NACHO'does this by visualising quality control metrics,expression of control genes,principal components and sample specificsize factors in an interactive web application.License GPL-3URL https:///mcanouil/NACHO/,https://m.canouil.dev/NACHO/ BugReports https:///mcanouil/NACHO/issuesDepends R(>=3.6.0)Imports utils,data.table,ggplot2(>=3.3.0),ggforce(>=0.3.1),ggrepel(>=0.8.1),knitr(>=1.25),rmarkdown(>=1.16),shiny(>=1.4.0),shinyWidgets(>=0.4.9)Suggests roxygen2(>=7.2.0),testthat(>=2.2.1),covr(>=3.3.2),Biobase,GEOquery,limmaVignetteBuilder knitrEncoding UTF-8LazyData trueRoxygenNote7.2.3SystemRequirements pandoc(>=1.12.3),pandoc-citeprocConfig/testthat/edition31NeedsCompilation noAuthor Mickaël Canouil[aut,cre](<https:///0000-0002-3396-4549>), Roderick Slieker[aut](<https:///0000-0003-0961-9152>),Gerard Bouland[aut]Maintainer Mickaël Canouil<*******************.dev>Repository CRANDate/Publication2023-08-0719:30:09UTCR topics documented:autoplot.nacho (2)check_outliers (4)deploy (4)GSE74821 (5)load_rcc (5)normalise (7)print.nacho (10)render (12)visualise (13)Index15 autoplot.nacho Plot quality-control metrics and thresholds of a"nacho"objectDescriptionThis function allows to plot any qualit-controlfigures available within the shiny app using visualise() or in the HTML report from render().Usage##S3method for class nachoautoplot(object,x,colour="CartridgeID",size=0.5,show_legend=TRUE,show_outliers=TRUE,outliers_factor=1,outliers_labels=NULL,...)Argumentsobject[list]List obtained from load_rcc()or normalise().x[character]Character string naming the quality-control metrics to plot from nacho_object.The possible values are:•"BD"(Binding Density)•"FoV"(Imaging)•"PCL"(Positive Control Linearity)•"LoD"(Limit of Detection)•"Positive"(Positive Controls)•"Negative"(Negative Controls)•"Housekeeping"(Housekeeping Genes)•"PN"(Positive Controls vs.Negative Controls)•"ACBD"(Average Counts vs.Binding Density)•"ACMC"(Average Counts vs.Median Counts)•"PCA12"(Principal Component1vs.2)•"PCAi"(Principal Component scree plot)•"PCA"(Principal Components planes)•"PFNF"(Positive Factor vs.Negative Factor)•"HF"(Housekeeping Factor)•"NORM"(Normalisation Factor)colour[character]Character string of the column in ssheet_csv or more generally in nacho_object$nacho to be used as grouping colour.size[numeric]A numeric controlling point size(ggplot2::geom_point()or line size(ggplot2::geom_line()).show_legend[logical]Boolean to indicate whether the plot legends should be plotted(TRUE) or not(FALSE).Default is TRUE.show_outliers[logical]Boolean to indicate whether the outliers should be highlighted in red (TRUE)or not(FALSE).Default is TRUE.outliers_factor[numeric]Size factor for outliers compared to size.Default is1.outliers_labels[character]Character to indicate which column in nacho_object$nacho shouldbe used to be printed as the labels for outliers or not.Default is NULL....Other arguments(Not used).Examplesdata(GSE74821)autoplot(GSE74821,x="BD")4deploy check_outliers Annotate a"nacho"object for outliersDescriptionAdd or update"is_outlier"column in the"nacho"field of an object from a call to load_rcc() or normalise()(nacho_object$nacho),using the current quality-control thresholds.Usagecheck_outliers(nacho_object)Argumentsnacho_object[list]A list object of class"nacho"obtained from load_rcc()or normalise(). ValueA[list]object of class"nacho".Examplesdata(GSE74821)nacho_object<-check_outliers(GSE74821)head(nacho_object$nacho)deploy Deploy(copy)the shiny application to the specified directoryDescriptionDeploy(copy)the shiny application to the specified directoryUsagedeploy(directory="/srv/shiny-server",app_name="NACHO")Argumentsdirectory[character]A character vector of one path to the new location.app_name[character]A character vector defining the shiny application name in the new location.GSE748215 Value[logical]A logical indicating whether the deployment is successfull(TRUE)or not(FALSE). Examplesdeploy(directory=".")if(interactive()){shiny::runApp("NACHO")}GSE74821A"nacho"object containing20samples of GSE74821datasetDescriptionNanoString nCounter RUO-PAM50Gene Expression Custom CodeSetUsageGSE74821FormatA[list]object of class"nacho".SourceGSE74821load_rcc Produce a"nacho"object from RCC NanoStringfilesDescriptionThis function is used to preprocess the data from NanoString nCounter.6load_rccUsageload_rcc(data_directory,ssheet_csv,id_colname=NULL,housekeeping_genes=NULL,housekeeping_predict=FALSE,housekeeping_norm=TRUE,normalisation_method="GEO",n_comp=10)Argumentsdata_directory[character]A character string of the directory where the data are stored.ssheet_csv[character]or[data.frame]Either a string with the name of the CSV of the sam-plesheet or the samplesheet as a data.frame.Should contain a column thatmatches thefile names in the folder.id_colname[character]Character string of the column in ssheet_csv that matches thefile names in data_directory.housekeeping_genes[character]A vector of names of the miRNAs/mRNAs that should be used ashousekeeping genes.Default is NULL.housekeeping_predict[logical]Boolean to indicate whether the housekeeping genes should be pre-dicted(TRUE)or not(FALSE).Default is FALSE.housekeeping_norm[logical]Boolean to indicate whether the housekeeping normalisation should beperformed.Default is TRUE.normalisation_method[character]Either"GEO"or"GLM".Character string to indicate normalisation us-ing the geometric mean("GEO")or a generalized linear model("GLM").Defaultis"GEO".n_comp[numeric]Number indicating the number of principal components to compute.Cannot be more than n-1samples.Default is10.Value[list]A list object of class"nacho":access[character]Value passed to load_rcc()in id_colname.housekeeping_genes[character]Value passed to load_rcc().housekeeping_predict[logical]Value passed to load_rcc().housekeeping_norm[logical]Value passed to load_rcc().normalisation_method[character]Value passed to load_rcc().remove_outliers[logical]FALSE.n_comp[numeric]Value passed to load_rcc().data_directory[character]Value passed to load_rcc().pc_sum[data.frame]A data.frame with n_comp rows and four columns:"Standard deviation", "Proportion of Variance","Cumulative Proportion"and"PC".nacho[data.frame]A data.frame with all columns from the sample sheet ssheet_csv and all computed columns,i.e.,quality-control metrics and counts,with one sample per row.outliers_thresholds[list]A list of the(default)quality-control thresholds used. Examplesif(interactive()){library(GEOquery)library(NACHO)#Import data from GEOgse<-GEOquery::getGEO(GEO="GSE74821")targets<-Biobase::pData(Biobase::phenoData(gse[[1]]))GEOquery::getGEOSuppFiles(GEO="GSE74821",baseDir=tempdir())utils::untar(tarfile=file.path(tempdir(),"GSE74821","GSE74821_RAW.tar"),exdir=file.path(tempdir(),"GSE74821"))targets$IDFILE<-list.files(path=file.path(tempdir(),"GSE74821"),pattern=".RCC.gz$")targets[]<-lapply(X=targets,FUN=iconv,from="latin1",to="ASCII")utils::write.csv(x=targets,file=file.path(tempdir(),"GSE74821","Samplesheet.csv"))#Read RCC files and formatnacho<-load_rcc(data_directory=file.path(tempdir(),"GSE74821"),ssheet_csv=file.path(tempdir(),"GSE74821","Samplesheet.csv"),id_colname="IDFILE")}normalise(re)Normalise a"nacho"objectDescriptionThis function creates a list in which your settings,the raw counts and normalised counts are stored, using the result from a call to load_rcc().Usagenormalise(nacho_object,housekeeping_genes=nacho_object[["housekeeping_genes"]],housekeeping_predict=nacho_object[["housekeeping_predict"]],housekeeping_norm=nacho_object[["housekeeping_norm"]],normalisation_method=nacho_object[["normalisation_method"]],n_comp=nacho_object[["n_comp"]],remove_outliers=nacho_object[["remove_outliers"]],outliers_thresholds=nacho_object[["outliers_thresholds"]])Argumentsnacho_object[list]A list object of class"nacho"obtained from load_rcc()or normalise().housekeeping_genes[character]A vector of names of the miRNAs/mRNAs that should be used ashousekeeping genes.Default is NULL.housekeeping_predict[logical]Boolean to indicate whether the housekeeping genes should be pre-dicted(TRUE)or not(FALSE).Default is FALSE.housekeeping_norm[logical]Boolean to indicate whether the housekeeping normalisation should beperformed.Default is TRUE.normalisation_method[character]Either"GEO"or"GLM".Character string to indicate normalisation us-ing the geometric mean("GEO")or a generalized linear model("GLM").Defaultis"GEO".n_comp[numeric]Number indicating the number of principal components to compute.Cannot be more than n-1samples.Default is10.remove_outliers[logical]A boolean to indicate if outliers should be excluded.outliers_thresholds[list]List of thresholds to exclude outliers.DetailsOutliers definition(remove_outliers=TRUE):•Binding Density(BD)<0.1•Binding Density(BD)>2.25•Field of View(FoV)<75•Positive Control Linearity(PCL)<0.95•Limit of Detection(LoD)<2•Positive normalisation factor(Positive_factor)<0.25•Positive normalisation factor(Positive_factor)>4•Housekeeping normalisation factor(house_factor)<1/11•Housekeeping normalisation factor(house_factor)>11Value[list]A list containing parameters and data.access[character]Value passed to load_rcc()in id_colname.housekeeping_genes[character]Value passed to load_rcc()or normalise().housekeeping_predict[logical]Value passed to load_rcc().housekeeping_norm[logical]Value passed to load_rcc()or normalise().normalisation_method[character]Value passed to load_rcc()or normalise().remove_outliers[logical]Value passed to normalise().n_comp[numeric]Value passed to load_rcc().data_directory[character]Value passed to load_rcc().pc_sum[data.frame]A data.frame with n_comp rows and four columns:"Standard deviation", "Proportion of Variance","Cumulative Proportion"and"PC".nacho[data.frame]A data.frame with all columns from the sample sheet ssheet_csv and all computed columns,i.e.,quality-control metrics and counts,with one sample per row.outliers_thresholds[list]A list of the quality-control thresholds used.raw_counts[data.frame]Raw counts with probes as rows and samples as columns.With"CodeClass"(first column),the type of the probes and"Name"(second column),the Name of the probes.normalised_counts[data.frame]Normalised counts with probes as rows and samples as columns.With"CodeClass"(first column)),the type of the probes and"Name"(second column),thename of the probes.Examplesdata(GSE74821)GSE74821_norm<-normalise(nacho_object=GSE74821,housekeeping_norm=TRUE,normalisation_method="GEO",remove_outliers=TRUE)if(interactive()){library(GEOquery)library(NACHO)#Import data from GEOgse<-GEOquery::getGEO(GEO="GSE74821")targets<-Biobase::pData(Biobase::phenoData(gse[[1]]))GEOquery::getGEOSuppFiles(GEO="GSE74821",baseDir=tempdir())10print.nacho utils::untar(tarfile=file.path(tempdir(),"GSE74821","GSE74821_RAW.tar"),exdir=file.path(tempdir(),"GSE74821"))targets$IDFILE<-list.files(path=file.path(tempdir(),"GSE74821"),pattern=".RCC.gz$")targets[]<-lapply(X=targets,FUN=iconv,from="latin1",to="ASCII")utils::write.csv(x=targets,file=file.path(tempdir(),"GSE74821","Samplesheet.csv"))#Read RCC files and formatnacho<-load_rcc(data_directory=file.path(tempdir(),"GSE74821"),ssheet_csv=file.path(tempdir(),"GSE74821","Samplesheet.csv"),id_colname="IDFILE")#(re)Normalise data by removing outliersnacho_norm<-normalise(nacho_object=nacho,remove_outliers=TRUE)#(re)Normalise data with"GLM"method and removing outliersnacho_norm<-normalise(nacho_object=nacho,normalisation_method="GLM",remove_outliers=TRUE)}print.nacho Print method for"nacho"objectDescriptionThis function allows to print text andfigures from the results of a call to load_rcc()or normalise().It is intended to be used in a Rmarkdown chunk.Usage##S3method for class nachoprint(x,colour="CartridgeID",print.nacho11 size=0.5,show_legend=FALSE,show_outliers=TRUE,outliers_factor=1,outliers_labels=NULL,echo=FALSE,title_level=1,xaringan=FALSE,...)Argumentsx[list]A list object of class"nacho"obtained from load_rcc()or normalise().colour[character]Character string of the column in ssheet_csv or more generally in nacho_object$nacho to be used as grouping colour.size[numeric]A numeric controlling point size(ggplot2::geom_point()or line size(ggplot2::geom_line()).show_legend[logical]Boolean to indicate whether the plot legends should be plotted(TRUE) or not(FALSE).Default is TRUE.show_outliers[logical]Boolean to indicate whether the outliers should be highlighted in red (TRUE)or not(FALSE).Default is TRUE.outliers_factor[numeric]Size factor for outliers compared to size.Default is1.outliers_labels[character]Character to indicate which column in nacho_object$nacho shouldbe used to be printed as the labels for outliers or not.Default is NULL.echo[logical]A boolean to indicate whether text and plots should be printed.Mainly for use within a Rmarkdown chunk.title_level[numeric]A numeric to indicate the title level to start with,using markdown style,i.e.,the number of"#".xaringan[logical]A boolean to format output for Xaringan slides....Other arguments(Not used).Examplesdata(GSE74821)print(GSE74821)12render render Render a HTML report of a"nacho"objectDescriptionThis function create a Rmarkdown script and render it as a HTML document.The HTML document is a quality-control report using all the metrics from visualise()based on recommendations from NanoString.Usagerender(nacho_object,colour="CartridgeID",output_file="NACHO_QC.html",output_dir=".",size=1,show_legend=TRUE,show_outliers=TRUE,outliers_factor=1,outliers_labels=NULL,clean=TRUE)Argumentsnacho_object[list]A list object of class"nacho"obtained from load_rcc()or normalise().colour[character]Character string of the column in ssheet_csv or more generally in nacho_object$nacho to be used as grouping colour.output_file[character]The name of the outputfile.output_dir[character]The output directory for the rendered output_file.This allows for a choice of an alternate directory to which the outputfile should be written(thedefault output directory is the working directory,i.e.,.).If a path is providedwith afilename in output_file the directory specified here will take prece-dence.Please note that any directory path provided will create any necessarydirectories if they do not exist.size[numeric]A numeric controlling point size(ggplot2::geom_point()or line size(ggplot2::geom_line()).show_legend[logical]Boolean to indicate whether the plot legends should be plotted(TRUE) or not(FALSE).Default is TRUE.show_outliers[logical]Boolean to indicate whether the outliers should be highlighted in red (TRUE)or not(FALSE).Default is TRUE.outliers_factor[numeric]Size factor for outliers compared to size.Default is1.outliers_labels[character]Character to indicate which column in nacho_object$nacho shouldbe used to be printed as the labels for outliers or not.Default is NULL.clean[logical]Boolean to indicate whether the Rmd and Rdatafile used to produce the HTML report are removed from output_dir.Default is TRUE.Examplesif(interactive()){data(GSE74821)render(GSE74821)}visualise Visualise quality-control metrics of a"nacho"objectDescriptionThis function allows to visualise results from load_rcc()or normalise()several quality-control metrics in an interactive shiny application,in which thresholds can be customised and exported.Usagevisualise(nacho_object)Argumentsnacho_object[list]A list object of class"nacho"obtained from load_rcc()or normalise(). Examplesif(interactive()){data(GSE74821)#Must be run in an interactive R session!visualise(GSE74821)}if(interactive()){library(GEOquery)library(NACHO)#Import data from GEOgse<-GEOquery::getGEO(GEO="GSE74821")targets<-Biobase::pData(Biobase::phenoData(gse[[1]]))GEOquery::getGEOSuppFiles(GEO="GSE74821",baseDir=tempdir())utils::untar(tarfile=file.path(tempdir(),"GSE74821","GSE74821_RAW.tar"),exdir=file.path(tempdir(),"GSE74821"))targets$IDFILE<-list.files(path=file.path(tempdir(),"GSE74821"),pattern=".RCC.gz$")targets[]<-lapply(X=targets,FUN=iconv,from="latin1",to="ASCII") utils::write.csv(x=targets,file=file.path(tempdir(),"GSE74821","Samplesheet.csv"))#Read RCC files and formatnacho<-load_rcc(data_directory=file.path(tempdir(),"GSE74821"),ssheet_csv=file.path(tempdir(),"GSE74821","Samplesheet.csv"),id_colname="IDFILE")visualise(nacho)#(re)Normalise data by removing outliersnacho_norm<-normalise(nacho_object=nacho,remove_outliers=TRUE)visualise(nacho_norm)#(re)Normalise data with"GLM"method and removing outliersnacho_norm<-normalise(nacho_object=nacho,normalisation_method="GLM",remove_outliers=TRUE)visualise(nacho_norm)}Index∗datasetsGSE74821,5autoplot.nacho,2character,3,4,6–9,11–13check_outliers,4data.frame,6,7,9deploy,4ggplot2::geom_line(),3,11,12ggplot2::geom_point(),3,11,12GSE74821,5list,3–9,11–13load_rcc,5load_rcc(),3,4,6–13logical,3,5,6,8,9,11–13normalise,7normalise(),3,4,8–13normalize(normalise),7numeric,3,6–9,11,12print.nacho,10render,12render(),2visualise,13visualise(),2,12visualize(visualise),1315。
FOXBORO I A Series HARDWARE产品规格说明书
FOXBORO ®The FBM214 HART ® Communication Input Interface Module provides eight input channels, each accepting a 4 to 20mA analog signal or a digital HART signal superimposed on a 4 to 20 mA analog input signal.FEATURESKey features of the FBM214 module are:Eight analog input channels, each accepting oneof the following inputs:•Standard 4 to 20 mA analog sensor signal •Digital HART Frequency Shift Keying (FSK) signal superimposed on a 4 to 20 mA analog input signal.FSK modem dedicated to each input channel forbi-directional digital communications with a HART field deviceAnalog to digital conversion of each of the 4to20mA input signals from the HART devicesSupport for the HART universal commandsnecessary to interface the field device with the I/A Series ® system databaseGalvanic isolation of the group of 8 inputchannels from ground and module logicCompact, rugged design suitable for enclosure inClass G3 (harsh) environmentsHigh accuracy achieved by sigma-delta dataconversions for each channelTermination Assemblies (TAs) for locally orremotely connecting field wiring to the FBM214Termination Assemblies for per channel internallyand/or externally loop powered transmitters.PSS 21H-2Z14 B4 Page 2OVERVIEWThe FBM214 HART Communication Input Interface Module contains eight 4to20mA group isolated analog input channels. The FBM214 supports any mix of standard 4to20mA devices and HART devices.The FBM214 serves as a HART communications field device host, enabling the I/A Series system to request and receive two digital messages per second from the field device. The message pass-through capability can be used to support HART universal, common practice, and device-specific commands, but not the burst communication mode. These commands are implemented using the Intelligent Field Device Configurator (IFDC — refer toPSS 21S-8A3 B3 for details).The FBM214 provides a common isolated power supply to power all eight channels. Optionally, the channels can be powered by an external power supply. However, when a common external power supply is used with two or more channels, a Cable Balun module is required to prevent channel cross talk.COMPACT DESIGNThe FBM214 has a compact design, with a rugged extruded aluminum exterior for physical protection of the circuits. Enclosures specially designed for mounting the FBMs provide various levels of environmental protection, up to harsh environments per ISA Standard S71.04.HIGH ACCURACYFor high accuracy, the module incorporates a Sigma-Delta converter which can provide new analog input values for each channel every 100 milliseconds.VISUAL INDICATORSLight-emitting diodes (LEDs) incorporated into the front of the module provide visual indication of the module’s operational status, and communication activity on the channels.EASY REMOVAL/REPLACEMENTThe module can be removed/replaced without removing field device termination cabling, power, or communications cabling.FIELDBUS COMMUNICATIONA Fieldbus Communication Module or a Control Processor interfaces the redundant 2 Mbps module Fieldbus used by the FBMs. The FBM214 module accepts communication from either path (A or B) of the redundant 2 Mbps fieldbus – should one path fail or be switched at the system level, the module continues communication over the active path.The use of an external power supply common to two or more loops requires a Cable Balun Module to maintain communication signal line balance.MODULAR BASEPLATE MOUNTINGThe module mounts on a modular baseplate which accommodates up to four or eight FBMs. The modular baseplate is either DIN rail mounted or rack mounted, and includes signal connectors for redundant fieldbus, redundant independent dc power, and termination cables.TERMINATION ASSEMBLIESField input signals connect to the FBM subsystem via DIN rail mounted TAs. The TAs used with theFBM214 are described in “TERMINATION ASSEMBLIES AND CABLES” on page8.PSS 21H-2Z14 B4Page 3CABLE BALUN MODULEThe Cable Balun module is used to maintain digital communication line balance for HART Transmitter to FBM loops that are powered from a common external power supply. This powering effectively connects one line of each loop together. Without the Baluns, in each loop so powered, the common connection at the external power supply, would cause near end crosstalk at the system end of the loop wiring cable. Loops using FBM internal power source do not require Baluns.The Cable Balun module contains multiple Baluns. One Balun segment is interconnected in each loop powered from an external power supply per the diagram above. There is one Cable Balun module.Figure 1. Cable Balun Module Cable Balun ModuleModule Model ModulePart No.No. of Balunsin the ModuleCBM-4P0903SV4PSS 21H-2Z14 B4Page 4FUNCTIONAL SPECIFICATIONSField Device ChannelsVERSION SUPPORTEDHART Protocol v6INTERFACE8 group-isolated channelsCOMMUNICATION TO THE DEVICEPoint-to-point, master/slave, asynchronous, half-duplex, at 1200 baud.ERROR CHECKINGParity on each byte, and one CRC check byte.SPEED2 messages per secondFASTEST ALLOWED ECB BLOCK PERIOD500 msecMAXIMUM DISTANCE (FBM214 TO FIELDDEVICE)Meets HART FSK physical layer specificationHCF_SPEC-54, Revision 8.1 [up to 3030 m(10000ft)](1).COMPLIANCE VOLTAGE18 V dc minimum at 20.5 mACURRENT INPUTSSense Resistor61.9 Ω nominalTotal Input Resistance280 Ω minimumAccuracy (Includes Nonlinearity)±0.03% of full scaleTemperature Coefficient50 ppm/ºCResolution15 bitsUpdate Rate100 msIntegration Time500 msCommon Mode Rejection>100 db at 50 or 60 HzNormal Mode Rejection>35 db at 50 or 60 HzMAXIMUM LOOP RESISTANCE280 Ω (not including the field device)(2)LOOP POWER SUPPLY PROTECTIONEach channel is galvanically group isolated,current limited and voltage regulated. All inputsare limited by their design to less than 30 mA. Ifthe current limit circuit shorts out, the current islimited to about 85 mA.FBM INPUT IMPEDANCE280 Ω minimumFBM INTERNAL POWER FOR FIELD DEVICE24 V dc ±10% common power supply for allchannels. Loop load limited to one device perchannel.ISOLATIONThe channels are not galvanically isolated fromeach other, but are galvanically isolated (bothoptical and transformer isolation) as a group from ground and module logic. Inputs use an internal FBM isolated power supply for field power. Themodule withstands, without damage, a potential of 600 V ac applied for one minute between the group-isolated channels and earth (ground).CAUTIONThis does not imply that these channels areintended for permanent connection tovoltages of these levels. Exceeding the limitsfor input voltages, as stated elsewhere in thisspecification, violates electrical safety codesand may expose users to electric shock. Fieldbus CommunicationCommunicates with its associated FCM or FCP via the redundant 2 Mbps module FieldbusHEAT DISSIPATION4 W (maximum)(1)The maximum allowable distance decreases when the loop is operated through an intrinsic safety barrier. The maximum distance ofthe field device from the FBM is a function of compliance voltage, wire gauge and voltage drop at the device.(2)In an intrinsic safety application, if a zener barrier is used between the FBM and the field device, the power supply must be set at24V dc +5%, -1%. There are no specific constraints with the use of galvanic barriers.PSS 21H-2Z14 B4Page 5 FUNCTIONAL SPECIFICATIONS (CONTINUED)Power RequirementsINPUT VOLTAGE RANGE (REDUNDANT)24V dc ±5%CONSUMPTION7 W (maximum)Regulatory ComplianceELECTROMAGNETIC COMPATIBILITY (EMC) European EMC Directive 89/336/EECMeets:EN 50081-2 Emission standardEN 50082-2 Immunity standardEN 61326 Annex A (Industrial Levels) CISPR 11, Industrial Scientific and Medical(ISM) Radio-frequency Equipment -Electromagnetic Disturbance Characteristics- Limits and Methods of MeasurementMeets Class A LimitsIEC 61000-4-2 ESD ImmunityContact 4 kV, air 8 kVIEC 61000-4-3 Radiated Field Immunity10 V/m at 80 to 1000 MHzIEC 61000-4-4 Electrical FastTransient/Burst Immunity2 kV on I/O, dc power and communicationlinesIEC 61000-4-5 Surge Immunity2kV on ac and dc power lines; 1kV on I/Oand communications linesIEC 61000-4-6 Immunity to ConductedDisturbances Induced by Radio frequencyFields10 V (rms) at 150 kHz to 80 MHz on I/O,dc power and communication linesIEC 61000-4-8 Power Frequency MagneticField Immunity30 A/m at 50 and 60 HzPRODUCT SAFETY (FBM AND CABLE BALUN) Underwriters Laboratories (UL) for U.S. andCanadaUL/UL-C listed as suitable for use inUL/UL-C listed Class I, Groups A-D;Division 2; temperature code T4 enclosurebased systems. These modules are also ULand UL-C listed as associated apparatus forsupplying non-incendive communicationcircuits for Class I, Groups A-D hazardouslocations when connected to specifiedI/A Series® processor modules as describedin the I/A Series DIN Rail MountedSubsystem User’s Guide (B0400FA). Wherepower is supplied by the FBM,communications circuits also meet therequirements for Class2 as defined inArticle725 of the National Electrical Code(NFPA No.70) and Section 16 of theCanadian Electrical Code (CSA C22.1).Conditions for use are as specified in theI/A Series DIN Rail Mounted SubsystemUser’s Guide (B0400FA).European Low Voltage Directive 73/23/EECand Explosive Atmospheres (ATEX) directive94/9/ECCENELEC (DEMKO) certified as EEx nA IICT4 for use in CENELEC certified Zone 2enclosure certified as associated apparatusfor supplying non-incendive field circuits forZone 2, Group IIC, potentially explosiveatmospheres when connected to specifiedI/A Series processor modules as describedin the I/A Series DIN Rail MountedSubsystem User’s Guide (B0400FA). Also,see Table1 on page9.Calibration RequirementsCalibration of the module or termination assembly is not required.PSS 21H-2Z14 B4Page 6ENVIRONMENTAL SPECIFICATIONS(3)OperatingTEMPERATUREModule-20 to +70°C (-4 to +158°F)Termination AssemblyPVC-20 to +50°C (-4 to +122°F)PA-20 to +70°C (-4 to +158°F) RELATIVE HUMIDITY5 to 95% (noncondensing)ALTITUDE-300 to +3,000m (-1,000 to +10,000ft)StorageTEMPERATURE-40 to +70°C (-40 to +158°F)RELATIVE HUMIDITY5 to 95% (noncondensing)ALTITUDE-300 to +12,000m (-1,000 to +40,000ft) ContaminationSuitable for use in Class G3 (Harsh) environments as defined in ISA Standard S71.04, based on exposure testing according to EIA Standard 364-65, Class III. Vibration7.5 m/S2 (0.75 g) from 5 to 500 Hz(3)The environmental limits of this module may be enhanced by the type of enclosure containing the module. Refer to the applicableProduct Specification Sheet (PSS) which describes the specific type of enclosure that is to be used.PSS 21H-2Z14 B4Page 7 PHYSICAL SPECIFICATIONSMountingMODULEFBM214 mounts on a modular baseplate. Thebaseplate can be mounted on a DIN rail(horizontally or vertically), or horizontally on a19-inch rack using a mounting kit. Refer toPSS21H-2W6B4 for details.TERMINATION ASSEMBLYThe TA mounts on a DIN rail and accommodates multiple DIN rail styles including 32mm (1.26in) and 35mm 1.38in).MassMODULE284 g (10 oz) approximateTERMINATION ASSEMBLYCompression181 g (0.40 lb) approximateRing Lug249 g (0.55 lb) approximateDimensions – ModuleHEIGHT102 mm (4 in)114 mm (4.5 in) including mounting lugsWIDTH45 mm (1.75 in)DEPTH104 mm (4.11 in)Dimensions – Termination AssemblySee page10.Part NumbersFBM214 MODULEP0922VTTERMINATION ASSEMBLIESSee “FUNCTIONAL SPECIFICATIONS –TERMINATION ASSEMBLIES” on page8. Termination CablesCABLE LENGTHSUp to 30 m (98 ft)CABLE MATERIALSPolyurethane or Hypalon®/XLPTERMINATION CABLE TYPEType 1 – See Table2 on page9.CABLE CONNECTION – TA25-pin male D-subminiatureConstruction – Termination AssemblyMATERIALPolyvinyl Chloride (PVC), compressionPolyamide (PA), compressionPVC, ring lugFAMILY GROUP COLORGreen – communicationTERMINAL BLOCKS3 tiers, 8 positionsField Termination ConnectionsCOMPRESSION-TYPE ACCEPTED WIRINGSIZESSolid/Stranded/AWG0.2 to 4 mm2/0.2 to 2.5 mm2/24 to 12 AWGStranded with Ferrules0.2 to 2.5 mm2 with or without plastic collarRING-LUG TYPE ACCEPTED WIRING SIZES#6 size connectors (0.375 in (9.5 mm))0.5 to 4 mm2/22 AWG to 12 AWGPSS 21H-2Z14 B4Page 8TERMINATION ASSEMBLIES AND CABLESField input signals connect to the FBM subsystem via DIN rail mounted Termination Assemblies, which are electrically passive.TAs for the FBM214 are available in the following forms: Compression screw type using Polyvinyl Chloride(PVC) materialCompression screw type using Polyamide (PA) material Ring lug type using PVC material.See the following “FUNCTIONAL SPECIFICATIONS –TERMINATION ASSEMBLIES” for a list of TAs used with the FBM214.The FBM214 provides sufficient loop resistance to allow use of the HART Hand-Held Terminal, or PC20 Intelligent Field Device Configurator (PSS 2A-1Z3 E).A removable termination cable connects the DIN railmounted TA to the FBM via a field connector on the baseplate in which the FBM is installed. Termination cables are available in the following materials: PolyurethaneHypalon XLP .Termination cables are available in a variety of lengths, up to 30 meters (98feet), allowing the Termination Assembly to be mounted in either theenclosure or in an adjacent enclosure. See Table 2 for a list of termination cables used with the TAs forthe FBM214.FUNCTIONAL SPECIFICATIONS – TERMINATION ASSEMBLIESFBM Type Input SignalTA Part NumberTermination TA Cable TACertification PVC (a)(a)PVC is polyvinyl chloride rated from -20 to +50°C (-4 to +122°F).PA is Polyamide rated from -20 to +70°C (-4 to +158°F).PA (a)Type (b)(b) C = TA with compression terminals; RL = TA with ring lug terminals.Type (c)(c)See Table 2 for cable part numbers and specifications.Type (d)(d)See Table 1 for Termination Assembly certification definitions.FBM2148 input channels, 4 to 20mA analog signal, alone or with HART signal superimposedP0916BX P0926EA P0926TD CRL11, 2PSS 21H-2Z14 B4Page 9Table 1. Certification for Termination AssembliesType Certification (a)(a)All TAs are UL/UL-C listed to comply with applicable ordinary location safety standards for fire and shock hazards. Hazardous locationtypes comply with ATEX directive for II 3 G use. They also comply with the requirements of the European Low Voltage Directive. All listings/certifications require installation and use within the constraints specified in DIN Rail Mounted Subsystem User’s Guide (B0400FA) and the conditions stated in UL and DEMKO reports.Type 1TAs are UL/UL-C listed as suitable for use in Class I; Groups A-D; Division 2 temperature code T4 hazardous locations. They are CENELEC (DEMKO) certified EEx nA IIC T4 for use in Zone 2 potentially explosive atmospheres.Type 2TAs are UL/UL-C listed as associated apparatus for supplying non-incendive field circuits Class I; Groups A-D; Division 2 hazardous locations when connected to specified DIN rail mounted FBMs and field circuits meeting entity parameter constraints specified in DIN Rail Mounted Subsystem User’s Guide (B0400FA). They are also CENELEC (DEMKO) certified as associated apparatus for supplying field circuits for Group IIC, Zone 2 potentially explosive atmospheres. Field circuits are also Class 2 limited energy (60 V dc, 30 V ac, 100 VA or less) if customer-supplied equipment meets Class 2 limits.Table 2. Cables Types and Part NumbersCable Lengthm (ft) Type 1P/PVC (a)Type 1H/XLPE (b)Cable Lengthm (ft) Type 1P/PVC (a)Type 1H/XLPE (b)0.5 (1.6)P0916DA P0916VA 10.0 (32.8) P0916DE P0916VE 1.0 (3.2) P0916DB P0916VB 15.0 (49.2) P0916DF P0916VF 2.0 (6.6)P0931RM P0931RR 20.0 (65.6) P0916DG P0916VG 3.0 (9.8) P0916DC P0916VC 25.0 (82.0) P0916DH P0916VH 5.0 (16.4)P0916DDP0916VD30.0 (98.4)P0916DJP0916VJ(a)P/PVC is polyurethane outer jacket and semi-rigid PVC primary conductor insulation.(b)H/XLPE is Hypalon outer jacket and XLPE (cross-linked polyethylene) primary conductor insulation.PSS 21H-2Z14 B4Page 10DIMENSIONS – NOMINALRELATED PRODUCT SPECIFICATION SHEETSCompression Termination AssemblyRing Lug Termination Assembly(a) Overall width – for determining DIN rail loading.(b) Height above DIN rail (add to DIN rail height for total).PSS NumberDescriptionPSS 21H-2W1 B3DIN Rail Mounted FBM Subsystem OverviewPSS 21H-2W2 B3DIN Rail Mounted FBM Equipment, Agency CertificationsPSS 21H-2Z14 B4Page 11PSS 21H-2Z14 B4 Page 12IPS Corporate Headquarters 5601 Granite Parkway Suite 1000 Plano, TX 75024United States of AmericaFoxboro Global Client Support Inside U.S.: 1-866-746-6477 Outside U.S.: 1-508-549-2424 or contact your local Foxboro representative.Facsimile: 1-508-549-4999Invensys, Foxboro, I/A Series and the IPS Logo are trademarks of Invensys plc, its subsidiaries, and affiliates. All other brand names may be trademarks of their respective owners.Copyright 2002-2010 Invensys Systems, Inc.All rights reservedMB 21A Printed in U.S.A. 0210。
Capadenoson_腺苷A1受体激动剂_544417-40-5_Apexbio
C1=CC(=CC=C1C2=C(C(=NC(=C2C#N)SCC3=CSC(=N3)C4=CC=C(C=C4) Cl)N)C#N)OCCO
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产品仅用于研究，
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每个产品具体的储存和使用信息显示在产品说明书中。ApexBio 产品在推荐的条件下是稳定 的。产品会根据不同的推荐温度进行运输。许多产品短期运输是稳定的，运输温度不同于长 期储存的温度。我们确保我们的产品是在保持试剂质量的条件下运输的。收到产品后，按照 产品说明书上的要求进行储存。
Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
生物活性
靶点 :
GPCR/G protein
信号通路:
Adenosine Deaminase
产品说明书
化学性质
产品名: Capadenoson 修订日期: 6/30/2016
产品名: Cas No.: 分子量: 分子式: 别名: 化学名:
SMILES:
溶解性: 储存条件: 一般建议:
运输条件:
Capadenoson
544417-40-5
520.03
C25H18ClN5O2S2
BAY 68-4986
Soluble in DMSO
Store at -20°C
Cisco ONS 15454产品说明书
B-1Cisco ONS 15454 Procedure Guide, R4.6August 2004A P P E N D I XBSpecificationsThis appendix contains hardware and software specifications for the ONS 15454.BandwidthThe ONS 15454 has the following bandwidth specifications:•Total bandwidth: 240 Gbps •Data plane bandwidth: 160 Gbps •SONET plane bandwidth: 80 GbpsConfigurationsThe ONS 15454 can be configured as follows:•Two-fiber path protection•Path protected mesh network (PPMN)•Two-fiber bidirectional line switch ring (BLSR)•Four-fiber BLSR •Add-drop multiplexer •Terminal mode •Regenerator mode •Hubbed rings •Multihubbed rings •Point-to-point •Linear•Linear with optical add/drop multiplexing (OADM)Appendix B Specifications Cisco Transport ControllerCisco Transport ControllerCisco Transport Controller (CTC), the ONS15454 craft interface software, has the followingspecifications:•10 BaseT•TCC2 access: RJ-45 connector•Backplane access: LAN pin fieldExternal LAN InterfaceThe ONS15454 external LAN interface has the following specifications:•10 BaseT Ethernet•Backplane access: LAN pin fieldTL1 Craft InterfaceThe ONS15454 TL1 craft interface has the following specifications:•Speed: 9600 bps•TCC2 access: EIA/TIA-232 DB-9 type connector•Backplane access: CRAFT pin fieldModem InterfaceThe ONS15454 modem interface has the following specifications:•Hardware flow control•TCC2: EIA/TIA-232 DB-9 type connectorAlarm InterfaceThe ONS15454 alarm interface has the following specifications:•Visual: Critical, Major, Minor, Remote•Audible: Critical, Major, Minor, Remote•Alarm contacts: 0.045 mm, –48 V, 50 mA•Backplane access: Alarm pin fieldsCisco ONS 15454 Procedure Guide, R4.6August 2004Appendix B SpecificationsEIA InterfaceEIA InterfaceThe ONS15454 EIA interface has the following specifications:•SMB: AMP #415504-3 75-ohm, 4-leg connectors•BNC: Trompeter #UCBJ224 75-ohm 4 leg connector (King or ITT are also compatible)•AMP Champ: AMP#552246-1 with #552562-2 bail locksBITS InterfaceThe ONS15454 BITS interface has the following specifications:• 2 DS-1 building integrated timing supply (BITS) inputs• 2 derived DS-1 outputs•Backplane access: BITS pin fieldSystem TimingThe ONS15454 has the following system timing specifications:•Stratum 3 per Telcordia GR-253-CORE•Free running accuracy: ± 4.6 ppm•Holdover stability: 3.7 x10–7/day, including temperature (< 255 slips in first 24 hours)•Reference: External BITS, line, internalPower SpecificationsSystem PowerThe ONS15454 has the following power specifications:•Input power: –48 VDC•Power consumption: 55 W (fan tray only); 650 W (maximum draw w/cards)•Power requirements: –40.5 to –57 VDC•Power terminals: #6 Lug•ANSI shelf: 100-A fuse panel (minimum 30 A fuse per shelf)HD shelf: 100-A fuse panel (minimum 35 A fuse per shelf)CardsTable B-1 provides power consumption information for the ONS 15454 cards.Cisco ONS 15454 Procedure Guide, R4.6 August 2004Cisco ONS 15454 Procedure Guide, R4.6August 2004Appendix B SpecificationsCardsT able B-1Individual Card Power RequirementsCard TypeCard Name Watts Amperes BTU/Hr.Control CardsTCC219.200.466.8XC 29.000.6099XCVT 34.400.72117.46XC10G 481163.68AIC 6.010.1220.52AIC-I 4.80.115.3AEP3(from +5VDC from AIC-I)10.2Electrical Cards EC1-1236.600.76124.97DS1-1412.600.2643.02DS1N-1412.600.2643.02DS3-1238.200.79130.43DS3N-1238.200.79130.43DS3i-N-12300.63102.4DS3-12E 26.800.5691.51DS3N-12E26.800.5691.51DS3XM-6 Transmux200.4268Appendix B SpecificationsCardsT able B-1Individual Card Power Requirements (continued)Card Type Card Name Watts Amperes BTU/Hr.Optical Cards OC3 IR 419.200.4065.56OC3 IR 4/STM1 SH 131019.200.4065.56OC3 IR 4/STM1SH 1310-826.000.4878.5OC12 IR 131010.900.2337.22OC12 LR 13109.280.231.68OC12 LR 15509.280.231.68OC12 LR/STM4 LH 1310 9.000.231.68OC12 LR/STM4 LH 15509.280.231.68OC12 IR/STM4 SH 1310-435.600.74121.6OC48 IR 131032.200.67109.94OC48 LR 155026.800.5691.50OC48 IR/STM16 SH AS 131037.200.77127.01OC48 LR/STM16 LH AS 155037.200.77127.01OC48 ELR/STM16 EH 100 GHz31.200.65106.53OC48 ELR 200 GHz31.200.65106.53OC192 SR/STM64 IO H 131041.80.90132.00OC192 IR/STM64 SH 155048.00 1.00163.68OC192 LR/STM64 LH 155041.80.9132.00OC192 LR/STM64 LH 15xx.xx62.40 1.30214.00TXP_MR_10G35.0010.73119.5MXP_2.5G_10G501 1.04170.7TXP_MR_2.5G35.0020.73119.5TXPP_MR_2.5G501 1.04170.5Cisco ONS 15454 Procedure Guide, R4.6 August 2004Cisco ONS 15454 Procedure Guide, R4.6August 2004Appendix B SpecificationsCardsDWDM CardsOSCM Nominal 23Maximum 26Nominal 0.48Maximum 0.54Nominal 78.48Maximum 88.71OSC-CSM Nominal 24Maximum 27Nominal 0.5Maximum 0.56Nominal 81.89Maximum 92.12OPT-PREMinimum 25Nominal 30Maximum39Minimum 0.52Nominal 0.5Maximum 0.81Minimum 85.3Nominal 102.36Maximum 88.71OPT-BST Nominal 30Maximum 39Nominal 0.63Maximum 0.81Nominal 102.36 Maximum 88.7132 MUX-O Nominal 16Maximum 25Nominal 0.33Maximum 0.52Nominal 54.59 Maximum 85.332 DMX-O Nominal 16Maximum 25Nominal 0.33Maximum 0.52Nominal 54.59 Maximum 85.34MD-xx.x Nominal 17Maximum 25Nominal 0.35Maximum 0.52Nominal 58.0Maximum 85.3AD-1C-xx.x Nominal 17Maximum 25Nominal 0.35Maximum 0.52Nominal 58.0Maximum 85.3AD-2C-xx.x Nominal 17Maximum 25Nominal 0.35Maximum 0.52Nominal 58.0Maximum 85.3AD-4C-xx.x Nominal 17Maximum 25Nominal 0.35Maximum 0.52Nominal 58.0Maximum 85.3AD-1B-xx.x Nominal 17Maximum 25Nominal 0.35Maximum 0.52Nominal 58.0Maximum 85.3AD-4B-xx.xNominal 17Maximum 25Nominal 0.35Maximum 0.52Nominal 58.0Maximum 85.3Ethernet CardsE100T-1265 1.35221.93E1000-253.50 1.11182.67E100T-G 65 1.35221.93E1000-2-G 53.50 1.11182.67G1000-463.00 1.31215.11ML100T-12531.10181.0ML1000-249 (incl. SFPs) 1.02167.3Fibre Channel FC_MR-46011.25212.001.Calculated power; measured power was not available at the time of publication.2.Calculated power; measured power was not available at the time of publication.T able B-1Individual Card Power Requirements (continued)Card TypeCard Name Watts Amperes BTU/Hr.B-7Cisco ONS 15454 Procedure Guide, R4.6August 2004Appendix B SpecificationsEnvironmental SpecificationsEnvironmental SpecificationsSystemThe ONS 15454 has the following environmental specifications:•Operating temperature: 0 to +55 degrees Celsius; –40 to +65 degrees Celsius with industrial temperature rated cards•Operating humidity: 5 to 95%, noncondensingCardsTable B-2 provides temperature ranges and product names for ONS 15454 cards.NoteThe I-Temp symbol is displayed on the faceplate of an I-Temp compliant card. A card without this symbol is C-Temp compliant.T able B-2Card T emperature Ranges and Product NamesCard TypeCard Name C-Temp Product Name (32 to 131 degrees Fahrenheit, 0 to +55 degrees Celsius)I-Temp Product Name (–40 to 149 degrees Fahrenheit, –40 to +65 degrees Celsius)Control CardsTCC2—15454-TCC2XC 15454-XC 15454-XC-T XCVT 15454-XC-VT 15454-XC-VT-T XC10G 15454-XC-10G —AIC 15454-AIC 15454-AIC-T AIC-I —15454-AIC-I AEP—15454-AEP Electrical EC1-1215454-EC1-1215454-EC1-12-T DS1-1415454-DS1-1415454-DS1-14-T DS1N-1415454-DS1N-1415454-DS1N-14-T DS3-1215454-DS3-1215454-DS3-12-T DS3N-1215454-DS3N-1215454-DS3N-12-T DS3i-N-1215454-DS3i-N-12—DS3-12E —15454-DS3-12E-T DS3N-12E—15454-DS3N-12E-T DS3XM-6 (Transmux)15454-DS3XM-615454-DS3XM-6-TCisco ONS 15454 Procedure Guide, R4.6August 2004Appendix B SpecificationsCardsOpticalOC3 IR 4/STM1 SH 131015454-OC34IR131015454-OC34I13-T OC3 IR/STM1 SH 1310-815454-OC3I8-1310—OC12 IR/STM4 SH 131015454-OC121IR131015454-OC121I13-T OC12 LR/STM4 LH 131015454-OC121LR131015454-OC121L13-T OC12 LR/STM4 LH 155015454-OC121LR155015454-OC121L15-T OC12 IR/STM4 SH 1310-415454-OC12I4-1310—OC48 IR 131015454-OC481IR1310—OC48 LR 155015454-OC481LR1550—OC48 IR/STM16 SH AS 131015454-OC481IR1310A —OC48 LR/STM16 LH AS 155015454-OC481LR1550A—OC48 ELR/STM16 EH 100 GHz 15454-OC48E-1-xx.xx(all wavelengts)—OC48 ELR/STM16 EH 200 GHz 15454-OC48E-xx.xx(all wavelengths)—OC 192 SR/STM64 IO 131015454-OC192IO1310—OC192 IR/STM64 SH 155015454-OC192IR1550—OC192 LR/STM64 LH 155015454-OC192LR1550—OC192 LR/STM64 LH ITU 15xx.xx 15454-OC192LR15xx—TXP_MR_10G 15454-TXPMR10G—MXP_2.5G_10G 15454-MXP2.5G10G —TXP_MR_2.5G 15454-2.5GMRTXP —TXPP_MR_2.5G15454-2.5GMRTXP-P—T able B-2Card T emperature Ranges and Product Names (continued)Card TypeCard NameC-Temp Product Name (32 to 131 degrees Fahrenheit, 0 to +55 degrees Celsius)I-Temp Product Name (–40 to 149 degrees Fahrenheit, –40 to +65 degrees Celsius)Cisco ONS 15454 Procedure Guide, R4.6August 2004Appendix B SpecificationsDimensionsDimensionsThe ONS 15454 shelf assembly has the following dimensions:•Height: 18.5 in. (40.7 cm)•Width: 19 or 23 in. (41.8 or 50.6 cm) with mounting ears attached •Depth: 12 in. (26.4 cm) (5 in. or 12.7 cm projection from rack)•Weight: 55 lb (24.947 kg) emptyDWDMOSCM 15454-OSCM —OSC-CSM 15454-OSC-CSM —OPT-PRE 15454-OPT-PRE —OPT-BST 15454-OPT-BST —32 MUX-O 15454-32 MUX-O —32 DMX-O 15454-32 DMX-O —4MD-xx.x 15454-4MD-xx.x —AD-1B-xx.x 15454-AD-1B-xx.x —AD-4B-xx.x 15454-AD-4B-xx.x —AD-1C-xx.x 15454-AD-1C-xx.x —AD-2C-xx.x 15454-AD-2C-xx.x —AD-4C-xx.x15454-AD-4C-xx.x —Fibre Channel FC_MR-415454-FC_MR-4—T able B-2Card T emperature Ranges and Product Names (continued)Card TypeCard Name C-Temp Product Name (32 to 131 degrees Fahrenheit, 0 to +55 degrees Celsius)I-Temp Product Name (–40 to 149 degrees Fahrenheit, –40 to +65 degrees Celsius)Appendix B Specifications DimensionsCisco ONS 15454 Procedure Guide, R4.6August 2004。
卡洛加吉电子有限公司产品：无线困扰保护设备说明书
Product DescriptionWireless Entrapment Pro-tection Device (EPD) for Industrial Gates. The system is designed to replace the connection cable between the ESPE (electro-sensitive protective equipment) and the gate controller. The sub-controller has input for either N.C. ESPE, N.O. 8.2 kΩ ESPE or the Carlo Gavazzi low con-sumption photoelectric ESPE N.C. contact. The system is designed for high reliabilityusing 2.4 GHz duplex com-munication between the main controller and sub controller. The main controller can han-dle up to 6 sub controllers i.e. one system can handle 12 ESPEs.The active time is initiated with a test signal applied on the main controller. The dura-tion of this can be fixed or defined by the length of the test signal.• Wireless Entrapment Protection Device for Industrial Gates• Input for two ESPE (electro-sensitive protective equipment)• Replaces cable between Gate controller and ESPE • Output ESPE: 2 x SPST NC or 2 x SPST NO (8,2kΩ) or 2 x Photoelectric sensors• Output low battery: 1 x SPST NC or NO • 2,4 GHz duplex communication • Built-in antenna • IP66 ratingsWireless Entrapment Protection Device For Industial Gates ESPEType WSM / WSS …Specifications Main Controller (WSM)Type SelectionHousing Range Output Type Ordering no.W x H x D Wireless75 x 125 x 35 mm 15 m NO 8K2 Main Controller WSM6GAOOD2475 x 125 x 35 mm 15 m NC Main Controller WSM6GACCD2445 x 214 x 22 mm 15 m-Sub Controller WSS2GA2BAT Housing Range Cable length TypeOrdering no. W x H x D S n Photoelectric Sensor Ø11 x 24.5 mm 2.5 m 2 m Emitter PB 11 CNT 15 WE Ø11 x 24.5 mm2.5 m12 mReceiverPB 11 CNT 15 WRICWSM/WSS ...Specifications Main Controller (WSM) (cont.)Specifications Sub Controller (WSS)NOTE: Changes/modifications not approved by Carlo Gavazzi could void the user’s authority to operate the equipment.WSM/WSS ...Specifications Photoelectric Sensors ESPE (PB11)NOTE: Changes/modifications not approved by Carlo Gavazzi could void the user’s authority to operate the equipment.Specifications Sub Controller (WSS) (cont.)(R&TTE) Directive 1999/5/EC Low Voltage Directive 2006/95/ECElectromagnetic Compatibility Directive 2004/108/EC Machinery Directive 2006/42/EC, amended by Directive 98/79/ECFor industrial doors onlySee EN13241-1Operation Diagram: Fixed Active TimeWSM/WSS ...Excess Gain PB111101001000E x c e s s g a i n110Distance (m)1003,332,8328,1(feet)Operation Diagram: Manual Active TimeWSM/WSS ...Detection Diagram PB11-60-40-202040600246810126,613,119,726,332,839,4Sensing range (m)(m )0(Feet)-196,9-131,2-65,665,6131,2196,90(F e e t )Wiring DiagramsYXEmitterReceiverLifetime of batteriesActive Duration in seconds3 Sub ctrl., 2 x optical sensors12 Cycles/day 25 Cycles/day 50 Cycles/day 100 Cycles/day 200 Cycles/day 400 Cycles/dayY e a r s0,00,40,20,60,81,01,21,41,61530604575901050,00,40,20,60,81,01,21,41530604575901053 Sub ctrl., 2 x Mech NO-8K2Active Duration in secondsY e a r sActive Duration in seconds 1 Sub ctrl., 2 x optical sensors12 Cycles/day 25 Cycles/day 50 Cycles/day 100 Cycles/day 200 Cycles/day 400 Cycles/dayY e a r s0,00,40,20,60,81,01,21,61,41530604575901050,00,40,20,60,81,01,21,41530604575901051 Sub ctrl.,2 x Mech. NO-8K2Active Duration in secondsY e a r sConditions: 240 working days, ambient temperature 20°C, 85% battery efficiency. ”Duration” is gate opening or closing time. One cycle is an opening AND closing cycle.4 x ER14505 3.6 VDC size AA, ≥ 2700 mAh Lithium batteriesNormal speedFast speedWSM/WSS ...WSM/WSS ... DimensionsDelivery Contents Main Controller •Wireless Main Controller: WSM6GAOOD24 orWSM6GACCD24• Manual•4 x SCREW M4.5X45 MM BOSSARD BN615•4 x RAWLPLUG SX8 NYLON• Packaging: Cardboard box Delivery Contents Sub Controller •Wireless Sub Controller: WSS2GA2BAT• Manual•2 x ER14505 3.6 VDC size AA, ≥ 2700 mAh Lithium batteries•4 x SCREW M4X10 MM BOSSARD BN1023• Packaging: Cardboard boxDelivery Contents Receiver •Receiver: PB11CNT15WR• Packaging: Plastic bag Delivery Contents Emitter •Emitter: PB11CNT15WE• Packaging: Plastic bag。
R.P.S. Corporation 34 产品系列说明书
3
4 18
16
17
SIDE BROOM MOTOR ASSY P/N 4-425
34 Parts Manual V3.1
Item
Part No.
1
4-111
2
4-113
3
4-220
4
4-223
5
4-376
6
4-378
7
4-381
8
4-385
9
4-386
10
4-402
11
4-404
12
4-436
13
Description MAIN BODY R. INNER SIDE PANEL SIDE BROOM MOTOR BROOM SAFETY DRIVE CPLG BROOM LIFT LEVER BROOM LIFT SHAFT LIFT LEVER BASE, RT LIFT LEVER COLLAR LIFT LEVER SPRING SIDE BROOM POLYPROPYLENE SIDE BROOM CLUTCH PLATE ADJ. BROOM LIFT BROOM MOUNTING BLOCK SIDE BROOM ARM BROOM RETAINING PLATE BROOM MOTOR MOUNT BROOM SHAFT DRIVE TUBE BEARING GROMMET-3/8 ID X 1-1/2 OD X .375 HANDLE GRIP SIDE BROOM LONG LINK ADJUSTMENT KNOB RIGHT FLOOR SEAL RH SEAL STRIP 3/8" X 1 1/4" SPRING PIN 1/4" X 1 1/2" CLEVIS PIN 1/4" X 1 1/4" SPRING PIN FB CASHD 1/4"-20 X 1/2" 1/2" X 1" CLEVIS PIN HCN 1/4"-20 SSS CP 1/4"-20 X 3/8" NYLOK #10-32 NYLOK 1/4"-20 HITCH PIN CLIP 9 HCS 1/4"-20 X 1/2 SS" HN 5/16"- 18 SS NYLOK 5/16" - 18 SS FW 5/8 ID X 1-1/2 OD SS LW 1/4" SS PPH #10-32 X 5/8" SS FHP 1/4"- 20 X 1-3/4" PPH SMS #8 X 3/4" SS #4 HAIR PIN HCS M6-1.0 X 14 SS 3/8" X 1 1/2" CLEVIS PIN
Modicon Quantum 32 O 型号 140DDO35300 产品数据表说明书
D i s c l a im er : T h i s d o c u m e n t a t i o n i s n o t i n t e n d e d a s a s u b s t i t u t e f o r a n d i s n o t t o b e u s e d f o r d e t e r m i n i n g s u i t a b i l i t y o r r e l i a b i l i t y o f t h e s e p r o d u c t s f o r s p e c i f i c u s e r a p p l i c a t i o n sProduct data sheetCharacteristics140DDO35300discrete output module Modicon Quantum - 32 O solid stateMainRange of productModicon Quantum automation platform Product or component type Dc discrete output module Discrete output number32ComplementaryGroup of channels 4 groups of 8Discrete output logic Positive logic (source)Addressing requirement 2 output words Discrete output voltage 24 V DC Output voltage limits 19.2...30 VAbsolute maximum output 56 V for 1.3 s decaying pulse Voltage drop0.4 V 0.5 A Maximum load current16 A per module 16 A per module 4 A per group 4 A per group Surge current <= 5 A for 0.0005 s Response time <= 1 ms at state 0 to state 1<= 1 ms at state 1 to state 0Leakage current 0.4 mA 30 VLoad inductance Inductance(H) = 0.5/((current(A))² x (switching frequency(Hz))) 50 Hz Fault indication Blown fuseLoss of field power Associated fuse rating3 A each point 3 A each point 5 A per group 5 A per groupIsolation between channels and bus 1780 Vrms DC for 1 minute Isolation between group 500 Vrms DC for 1 minuteProtection typeInternal output protection by 5 A fuse per groupPower dissipation 1.75 W + (0.4 V x total module load current)Marking CELocal signalling1 LED green bus communication is present (Active)1 LED red external fault detected (F)32 LEDs green input status Bus current requirement 330 mA 330 mA Module format Standard Product weight0.45 kgEnvironmentProduct certificationsABS BV C-Tick DNVFM Class 1 Division 2GL GOST RINA RMRSSafety certification non interfering StandardsCSA C22.2 No 142UL 508Resistance to electrostatic discharge 4 kV contact conforming to IEC 801-28 kV on air conforming to IEC 801-2Resistance to electromagnetic fields 10 V/m 80...2000 MHz conforming to IEC 801-3Ambient air temperature for operation 0...60 °C Ambient air temperature for storage -40...85 °CRelative humidity 95 % without condensation Operating altitude<= 5000 mOffer SustainabilitySustainable offer status Green Premium productRoHS (date code: YYWW)Compliant - since 0848 - Schneider Electric declaration of conformity Schneider Electric declaration of conformity REAChReference not containing SVHC above the threshold Reference not containing SVHC above the threshold Product environmental profileAvailableProduct environmental Product end of life instructionsAvailableEnd of life manualContractual warrantyWarranty period18 monthsDimensions DrawingsRacks for Modules MountingDimensions of Modules and Racks(1) 2 slots (2) 3 slots (3) 4 slots (4) 6 slots (5)10 slots (6)16 slotsConnections and Schema24 Vdc Discrete Output Source Module Wiring Diagram。
PII英文说明书
PROTEAN®II xi Celland PROTEAN II xi 2-D Cell Instruction ManualFor Technical ServiceCall Your Local Bio-Rad Office orin the U.S. Call 1-800-4BIORAD(1-800-424-6723)Table of ContentsPage Section 1General Information (1)1.1Introduction (1)1.2Specifications (1)1.3Safety (2)Section 2Description of Major Parts (3)2.1Central Cooling Core (3)2.2Sandwich Clamps (3)2.3Casting Stand (3)2.4Upper Buffer Chamber (4)2.5Lower Buffer Chamber (4)2.6Lid (4)2.7Tube Gel Adaptor (4)2.8Alignment Card (4)Section 3Assembling the Glass Plate Sandwiches (4)3.1Assembling Single Sandwiches (4)3.2Assembling Multiple or “Double-up” Gel Sandwiches (8)Section 4Casting the Gels (9)4.1Casting Discontinuous (Laemmli) Gels (9)4.2Casting Continuous Gels (12)4.3Casting Gradient Gels (12)4.4Casting Agarose Gels (13)Section 5Assembling the Upper Buffer Chamber (15)5.1Assembly (15)5.2Use of the Buffer Dam (17)Section 6Loading the Samples (18)6.1Loading of Sample Wells (18)6.2Loading a Single Sample Per Gel (19)6.3Gels as Samples (19)Section 7Running the Gel (19)Section 8Set-up Options (20)8.1Buffer Recirculation (20)8.2Cooling Options (21)Section 9Removing the Gels (22)Section 10Two-Dimensional Electrophoresis (23)10.1Sequence of Steps for 2-D Protocol (24)10.2Protocol for IEF First Dimension (24)Section 11Maintenance of Equipment (30)Section 12Troubleshooting Guide - PAGE, SDS-PAGE, 2-D IEF/SDS-PAGE (31)Section 13Equipment and Accessories (33)13.1PROTEAN II xi Cell - Slab Configurations (33)13.2Accessories (33)13.3PROTEAN II xi Cell - 2-D Configuration (36)13.4Accessories (36)13.5Electrophoresis Chemicals (37)13.6Power Supplies (38)Section 14Appendix (39)14.1Reagents and Gel Preparation for SDS-PAGE Slab Gels (39)14.2Separating Gel Preparation (40)14.3Stacking Gel Preparation (41)14.4Running Conditions (41)14.5Comparison of Coomassie Blue and Silver Staining (42)14.62-D Stock Solutions (42)14.7Running Conditions (43)Section 15Appendix (44)15.1General References (44)15.2Native Gel Systems References (44)15.3SDS Gel Systems References (44)15.4Urea Gel Systems References (44)15.5Two-Dimensional IEF / SDS-PAGE Gel Systems References (44)Section 1General Information1.1 IntroductionThe PROTEAN II xi cell is a vertical slab electrophoresis instrument which combines versatility with practicality. When used with the various combs, spacers, and accessories avail-able, the PROTEAN II xi cell is suitable for most common electrophoretic techniques, including SDS electrophoresis, two-dimensional (2-D) electrophoresis, native electrophoresis, and agarose gel electrophoresis. The PROTEAN II xi cell can run up to 4 slab gels or 16 tube gels simultaneously. The basic unit accommodates gels 16 or 20 cm long. The 20 cm gels offer increased resolution capability, which is especially useful in 2-D applications.The central cooling core of the PROTEAN II xi cell assures even heat distribution over the entire gel length, permitting excellent resolution with minimal band distortion. Only 1.5 liters of buffer are required. The raised electrode position insures safe operation even with extended overnight runs.The unique single-screw sandwich clamps allow rapid assembly of the gel sandwich-es, while providing even pressure distribution along the entire gel length. This even pres-sure minimizes the risk of breaking the glass plates, a common problem with multi-screw clamps. The PROTEAN II xi alignment card helps keep spacers upright during sandwich alignment. The combination of the clamps, alignment card, and the casting stand permits assembly and casting of gels in minutes, with little effort. After casting, the completed gel sandwich attaches to the central cooling core with a single motion.The PROTEAN II xi cell is the instrument of choice for 2-D electrophoresis. With the optional tube adaptors, one can run the first dimension IEF tube gel, and then overlay this gel onto the second dimension SDS slab gel. Thus, the complete 2-D procedure can be done with one dedicated instrument.1.2 SpecificationsConstruction:Cooling core andtube gel adaptor molded polysulfoneLid and lower bufferchamber molded polycarbonateClamps, casting glass and Teflon®-filled molded poly-stand, and cams carbonateElectrical leads flexible, coiledElectrodes platinum, 0.010 inch diameter(0.254 mm)Shipping weight11 kg (24 lb, 3 oz)Overall size26 cm (L) x 19 cm (W) x 30 cm (H)Gel size16 x 16 cm slab or 16 x 20 cm slab1 to 6 mm diameter tube gelsGlass plate sizes16 cm cell:16 x 20 cm (inner plate)18.3 x 20 cm (outer plate)Cooling core, maximumflow rate 2 liter/minMaximum coolant temperature Do not exceed 50 °CVoltage limit1,000 volts DCTeflon is a registered trademark of E. I. DuPont de Nemours and Co.Section 2Description of Major PartsFig. 2.1. PROTEAN II xi 2-D cell including tube adaptor. 1.Lower buffer chamber, 2.Lid with elec-trical leads in place, 3.Cooling core with glass plate sandwich attached and core caps in place, 4.Casting stand with glass plate sandwich in alignment slot, 5.Tube gel adaptor, 6.Sandwich clamps,7.Buffer dam, 8.Alignment card.2.1 Central Cooling CoreThe central cooling core provides the cooling capability which prevents thermal band distortion during electrophoretic separations. The cooling core can be connected to any circulating cooling source. The serpentine flow pattern assures even heat distribution over the entire gel area. An ethylene glycol:water (20:80) solution is recommended as coolant.Other coolants may damage the plastic during extended exposure. If a circulating bath is not available, the core can be connected to a tap water line, or simply filled with 1.8 liters of coolant and plugged to act as a heat sink during electrophoresis.The central cooling core has a raised upper electrode which is housed in a protective cas-ing, and the lower electrode is recessed to prevent accidental damage.2.2 Sandwich ClampsThe unique PROTEAN II xi sandwich clamps consist of a single screw mechanism which makes assembly, alignment, and disassembly of the gel sandwich an effortless task.The clamps exert an even pressure over the entire length of the glass plates, providing a leak-proof seal and preventing plate damage due to uneven pressure. Each pair of clamps consists of a left clamp and a right clamp. The sandwich clamps can accommodate up to two1.5 mm thick gels.2.3 Casting StandThe casting stand is separate from the PROTEAN II xi cell so that two gel sandwich-es can be cast while others are being run. The one-piece molded unit has two casting slots and one alignment slot. Gel sandwiches are assembled, aligned, and cammed into the stand quickly, without the use of grease.Double gels may also be cast. Two 1.5 mm (or thinner) gels may be cast in each sand-wich, so that up to four 1.5 mm gels can be run at once.876543212.4 Upper Buffer ChamberThe completed gel sandwich attaches to the central cooling core so that the outer plate of the sandwich forms the side of the upper buffer chamber. The inner plate is clamped against a rubber gasket on the central cooling core to provide a greaseless, leak-free seal for the upper buffer. Each sandwich forms one side of the cathode chamber. Tube gel adaptors also snap onto the central cooling core to form the upper buffer chamber walls (one adap-tor per side). If only one gel is to be run, an upper buffer dam is attached to the core to form the complete upper buffer chamber. The upper buffer chamber will hold approxi-mately 350 ml of buffer when full.2.5 Lower Buffer ChamberThe lower buffer chamber of the PROTEAN II xi cell encloses the unit and provides sta-bility during electrophoresis. The molded unit requires a minimum buffer volume of only1.1 liters for 20 cm plates, while providing excellent heat exchange through the centralcooling core.2.6 LidCombined with the lower buffer chamber, the lid acts to fully enclose the PROTEAN II xi cell during electrophoresis, thus providing electrical insulation. The lid cannot be removed without disconnecting the electrical circuit. It can be placed on the lower cham-ber in only one alignment, so that the anode and cathode connections cannot be accidentally reversed. The lid also holds the coiled electrical leads when not in use.2.7 Tube Gel AdaptorThe tube gel adaptor clamps onto the central cooling core in one easy motion and pro-vides a leak-proof seal for the upper buffer chamber at voltages up to 1,000 V (especially useful for 2-D applications). The molded construction produces a lightweight, yet durable adaptor unit, which has a gel tube locator at the bottom to hold the tubes in a vertical ori-entation. Each adaptor can hold up to 8 tubes (from 1.0 mm ID to 6 mm ID); 16 tube gels can be run at once using two tube adaptors.Note:The upper buffer dam may not be used opposite a tube gel adaptor.2.8 Alignment CardThe alignment card greatly simplifies sandwich assembly by keeping the spacers upright during sandwich alignment. A sandwich is assembled by placing two spacers on top of the large outer plate. The alignment card is placed between the two spacers, and the shorter inner plate is then placed on top. Following attachment of the clamps, the sandwich assembly is transferred to the alignment slot of the casting stand for final adjustments.Section 3Assembling the Glass Plate Sandwiches3.1 Assembling Single SandwichesNote:Instructions for assembling 16 cm and 20 cm sandwiches are identical, except,of course, for the lengths of the components. To insure proper alignment, make sure allplates and spacers are clean and dry before assembly. The PROTEAN II xi plate wash-er/holder simplifies glass plate washing and also makes an ideal storage system forclean, dry glass plates. Each plate holder will accommodate up to 8 PROTEAN II xi platesor up to 18 Mini-PROTEAN®II plates.1.Assemble the gel sandwich on a clean surface. Lay the long rectangular plate downfirst, then place two spacers of equal thickness along the long edges of the rectangular plate. Next, place a short plate on top of the spacers so that it is flush with one end of the long plate.2.Locate both the right and left sandwich clamps, and loosen the single screw of each byturning counterclockwise. Place each clamp by the appropriate side of the glass plate stack, with the locating arrows facing up and toward the glass plates.3.Grasp the whole glass plate sandwich firmly with your right hand. With your left handguide the left clamp onto the sandwich so that the long and short plates fit the appro-priate notches in the clamp. Tighten the single screw enough to hold plates in place.4.Place the right clamp on the right side of the plates, and tighten the clamp screw.5.Level the casting stand on a flat surface with the alignment slot facing you. Check tosee that gaskets are clean and free of residual acrylamide to insure a good seal. Placea flat, grey, silicone gasket in each casting slot.Note:Always use the alignment slot to properly orient the gel sandwich. Failure to use this slot for alignment can result in casting leaks while pouring the gel or buffer leaks during the run.6.Place the assembled gel sandwich in the alignment slot of the casting stand. Loosen theclamp screws, and allow the plates and spacers to align at the surface of the alignment slot. Insert a PROTEAN II xi alignment card between the two glass plates to keep the spacers upright while additional alignment adjustments are made. As an alternative, the alignment card can be positioned between the glass plates when the sandwich is first assembled as in step 1.7.Simultaneously push inward on both clamps at the locating arrows, and tighten both clampscrews just enough to hold the sandwich in place. Pushing inward on both clamps at a point below the locating arrows will insure that the spacers and glass plates are flush against the sides of the clamps.8.Loosen one clamp screw slightly. While pushing down on the spacer with one finger,tighten the clamp screw finger-tight with the other hand (see photo). This will insure prop-er sealing when solution is poured. Tighten the other clamp screw in the same manner.It is important to visually inspect the sandwich while it is in the alignment slot to insure that there are no gaps between the glass plates and the surface of the alignment slot.9.Remove the alignment card. Pull the gel sandwich from the alignment slot. Check thatthe plates and spacers are flush at the bottom.If not, realign the gel sandwich as in steps 6-8.Note: The easiest way to check for proper alignment is to run a fingernail across the con-tact area between the glass plates and spacer. If your fingernail catches or drops as you move from plate to spacer to plate, you must realign the sandwich before proceeding to step 10.10.The cams on the casting stand should be handle up and pulled out. Place the aligned sand-wich into one of the casting slots with the longer plate facing you (and the arrows on the clamp facing away from you). When the sandwich is placed correctly, push the cams in, and turn them 180°so that the handles of the cams point downward. The sand-wiches are now ready for gel casting.3.2 Assembling Multiple or “Double-up” Gel SandwichesUp to four gels can be run at one time by doubling up gel sandwiches (i.e., 2 gels/side). Double gels are assembled, aligned, and cammed in a manner very similar to that described for single gels.Note: In order to run four gels instead of two, it is necessary to order two notched inner glass plates and a set of four spacers of equal length.y down a long rectangular plate, two spacers, and a notched inner plate.8.Place a comb in the gel sandwich, and tilt it so that the teeth are at a slight (~10°) angle.This will prevent air from being trapped under the comb teeth while pouring the monomer solutions.9.Add APS and TEMED to the degassed monomer solution, and pour the solution downthe spacer nearest the upturned side of the comb. Pour until all the teeth have been covered by solution. Then properly align the comb in the sandwich, and add monomer to fill completely.Generally, an overlay solution is not necessary for polymerization when a comb is in place.10.Allow the gel to polymerize 30-45 minutes. Remove the comb by pulling it straightup slowly and gently.11.Rinse the wells completely with distilled water. The gels are now ready to be attachedto the central cooling core, the sample loaded, and the gels run.4.2 Casting Continuous GelsContinuous gels are ones in which the entire gel is of one composition. This type of gel is often used in non-denaturing (native) buffer systems.1.Prepare the monomer solution. Combine all reagents except APS and TEMED. Degasunder vacuum for at least 15 minutes.2.Place a comb in the glass sandwich so that the teeth are tilted at approximately a 10°angle.3.Add APS and TEMED to the degassed monomer solution, and use a pipet and bulb topour the solution down the spacer nearest to the upturned side of the comb. Pour until the bottoms of all the teeth are covered. Then adjust the comb to its proper position. Add monomer solution to fill the sandwich completely. No overlay solution is necessary.4.Let the gel polymerize for 45 minutes to 1 hour. The gel is now ready to load and run.Remove the comb, and rinse thoroughly with distilled water.4.3 Casting Gradient GelsPolyacrylamide concentration gradients, made with an external gradient former (Model 385, catalog number 165-2000), can be introduced into the PROTEAN II xi gel sandwich assembly either from the bottom or from the top. A peristaltic pump is required for intro-duction from the bottom. Introduction from the top can be done by gravity flow or with a peristaltic pump. Follow the gradient former instructions for formulating the gradient. If gra-dients are pumped into the gel sandwich from the bottom, the low density solution (low per-cent monomer) must enter first. If the gradient enters from the top, the high density solution (high percent monomer) enters first.Pouring Gradient Gels from the Bottom1.After assembling the gel sandwich as described in Section 4, attach the gradient formertubing to a gradient pouring needle (catalog number 165-2007).2.Cam the gel sandwich to the casting stand, turn the casting stand on its side, locate thebottom filling ports directly under the space in the sandwich, and insert the bottom-fill needle through the rubber gasket, so that it protrudes about 2 mm into the sandwich. Make sure the needle opening faces one of the glass plates.3.Stand the casting stand up on a level surface, add APS and TEMED to the monomer solu-tions, and begin pumping the gradient monomer solution.4.Once the gradient is poured (this should take no more than 10 minutes from the time theinitiators are added to the first monomer solution), withdraw the needle from the gas-ket, and immediately clean the gradient former, tubing, and needle by pumping dis-tilled water through them.5.Overlay the monomer solution (see Section 4.1), or insert the comb (see Section 4.2),depending on whether the gel is discontinuous or continuous, respectively.Pouring Gradient Gels by Top-Filling1.Attach the gradient maker tubing to a needle (catalog number 165-1943), a long can-nula, or a piece of tubing that will fit between the glass plates of the gel sandwich.2.Insert the needle, cannula, or tubing as far as possible into the sandwich, and center it.3.Add APS and TEMED to the monomer solution, and begin pumping the gradient. Asthe monomer level in the sandwich approaches the tip of the needle, withdraw the nee-dle slowly, so that it always stays above the monomer level.4.Immediately rinse any remaining monomer out of the needle by pumping water throughthe gradient former and out the needle.5.Overlay the gel, or insert the comb, as outlined in Sections 4.1 and 4.2, respectively.4.4 Casting Agarose GelsAgarose gels in vertical apparatus may slide down between the glass plates. To prevent this, one of the two plates used to form the agarose gel sandwich should be a frosted inner plate (catalog number 165-1825 for 16 cm gels and catalog number 165-1826 for 20 cm gels).1.Assemble the glass plate sandwich as outlined in Section 3, using one frosted plate andone regular clear plate. The frosted plate should be the shorter inner plate (the plate on the inside during running). This will allow visualization of the tracking dye during the run. Make sure that the frosted side of the plate is on the inside of the gel sandwich.2.Place the sandwich assembly in a warm air incubator (50°C) for 5-10 minutes beforecasting the gel. This will prevent premature gelling of the agarose.3.Cam the warm assembly to the casting stand.4.Immediately pour the molten (55 to 60°C) agarose. One convenient method of pour-ing is to tilt the sandwich assembly and pour agarose directly down the long rectangu-lar glass plate.Note:If an incubator is not available, molten (75 to 85°C) agarose can be poured intoa room temperature sandwich assembly. This temperature is high enough to prevent pre-mature gelling of the agarose, yet low enough to prevent cracking of the glass plates.5.Insert the prewarmed comb carefully.6.Allow the agarose to cool to ambient temperature before use.7.Remove the comb very slowly to avoid tearing the gel.Note:There are some special tricks to properly remove a comb from a vertical agarose gel. The most important point is to introduce water or buffer under the comb while it is being removed. To introduce buffer or water, use a squirt bottle or a needle and syringe to force fluid under the teeth of the comb while it is slowly removed from the gel. Another option is to insert the comb only partway into the gel. This can easily be done with the aid of comb conversion screws (catalog number 165-1859). The three standard screws on the comb are replaced with the three large head comb conversion screws, with the protruding head of the conversion screws resting on top of the longer outer glass plate. The well depth of the comb is limited to 10 mm instead of the stan-dard 25 mm well depth.Section 5Assembling the Upper Buffer Chamber 5.1 Assembly y the central cooling core down flat on a lab bench. Make sure the core caps are in place on the cooling core ports.2.Seat the white U-shaped gasket onto the core with the flat (non-stepped) side down.Note:To help insure a good upper buffer seal with your gaskets for the PROTEAN II xi cell, lubricate the entire front of the gaskets (the shaded portion) with water or upper buffer prior to attaching the gel sandwich to the central cooling core. This will allow the glass plate sandwich to slide onto the gasket properly.3.After the gel is cast and the comb is removed (if applicable), release the gel sandwich from the casting stand by turning the cams to the “up” position and pulling them out-ward. Pull the gel sandwich straight out of the stand.A. Comb conversion screw.B. Standard comb screw.4.With the short glass plate facing the cooling core (and the locating decal on the clampsfacing the core), position the gel sandwich so that the grooves in the upper portion of the clamps are fitted onto the locating pins on the central cooling core.* The gel sand-wich should be positioned at an angle of ≤20°with the cooling core. Keeping this angle to a minimum and lubricating the gasket will prevent distortion of the gasket while the sandwich slides into place.*Note:The locating pins on the central cooling core must be tightly secured in place to insure optimal pressure during operation. If these pins are vibrated loose during transport or repeated use, the decrease in pressure on the clamp can be enough to allow the cell to leak. If the pins are loose, they can be gently tightened using a coin or screw-driver.5.With your fingers below the latch on the cooling core and your thumbs resting on theclamps, gently push the gel sandwich onto the cooling core with one simple motion. The upper edge of the short inner glass plate should be butted against the notches of the U-shaped gasket, and the tabs of each clamp should be held securely against the latch assemblies on both sides of the cooling core.6.Turn the central cooling core to its other side, and repeat steps 1 through 5 to attach thesecond gel sandwich to it.Note:When the gel sandwich has been properly installed, the shorter inside glass plate will be forced against the notch in the U-shaped gasket to create a leak-proof seal.Always inspect the contact between the gasket and glass plate to make sure the glass plate is butted against the notch in the gasket and is not resting on top of or below this notch.Improper installation of the gel sandwich can result in buffer leakage during the run. Asa standard procedure, pour buffer into the upper buffer compartment, and check forbuffer leaks prior to a run. In addition, we recommend marking the level of the upper buffer on the glass plates prior to electrophoresis. Checking this level after 1-2 hours will show whether a slow leak is occurring. This is especially important when the elec-trophoresis cell is being used for overnight experiments.5.2 Use of the Buffer DamIf only one gel is to be run, the acrylic buffer dam must be attached to the cooling core on the other side to form the complete upper buffer chamber. Position the acrylic plate between two clamps by matching the notches on the clamps to the notches on the acrylic plate (as in Section 3.1, steps 2-3), and then slide the dam up each clamp as far as possible. No further alignment is necessary. The acrylic buffer dam fits both 16 and 20 cm clamps.Note:We do not recommend the use of the acrylic buffer dam at elevated temperaturesas the block may warp and cause buffer leaks.Note:Failure to slide the dam up completely to the top of the clamp will result in an upperbuffer leak.Section 6Loading the SamplesSample loading can be done in one of three ways. The most common method is to load liquid samples into wells formed by casting a gel with a well-forming comb. The second method uses the entire gel surface as a single well for liquid samples. The third method involves placing a tube gel or gel strip over the entire gel surface, as in 2-D procedures.6.1 Loading of Sample WellsThe approximate sample volumes that each well will hold for all available combs is included in Section 13.2.1.Prepare 1.5 liters of electrode buffer. Set aside 350 ml for the upper buffer chamber.2.Pour 325-350 ml of electrode buffer into the upper buffer chamber. At this point, checkthe integrity of the upper buffer seal. If the buffer appears to be leaking, remove thegel sandwich assemblies, re-lubricate the gasket, and then re-attach the gel sandwichassemblies (as in Section 5).3.Place the remainder of the electrode buffer into the lower buffer chamber. Lower the cen-tral cooling core into the lower buffer chamber at a slight angle to prevent air entrapmentunder the gel sandwich. A few, isolated bubbles under the gel will not affect the run. With16 cm plates, it is necessary to dilute the lower buffer with distilled water to a level of1 cm above the bottom of the gel plates. Be sure to mix the lower buffer well with a stirbar on a magnetic stirrer.Note:Dilution of the lower buffer by up to 1:2 with dH2O will have no detrimentaleffect on resolution. Dilution of the upper buffer is not recommended.4.Load the samples into the wells under the electrode buffer with a Hamilton syringe.Insert the syringe to about 1-2 mm from the well bottom before delivery. Disposable pieces of plastic tubing may be attached to the syringe to eliminate the need for rinsing the syringe between samples.Note:The sample buffer must contain either 10% sucrose or glycerol in order to under-lay the sample in the well without mixing.5.An easier method of sample loading is to use an Eppendorf-like pipettor and disposabletips. To accomplish this successfully, use the optional beveled short plate (catalog num-ber 165-1827 for 16 cm and 165-1828 for 20 cm) so that you can insert the pipet tip fur-ther into the well before sample delivery. This will prevent inter-well mixing of samples.Or, use the Bio-Rad Prot-Elec tips (catalog number 223-9915 or 223-9917), which aredesigned for loading samples into wells.6.2 Loading a Single Sample Per GelIn this procedure, a gel is cast without using a comb, forming a flat gel surface. This gel is cast with an overlay solution. This type of sample application can be used for preparative purposes, but it is most often used in blotting applications. After electrophoresis, the sam-ple is transferred electrophoretically to a membrane, which then can be cut into several identical strips for analysis. Follow the instructions for casting the separating portion of a discontinuous gel (Section 4.1), except pour the gel nearly to the top of the sandwich. Allow just enough room for sample loading. (A stacking gel may also be added to this type of gel.)1.Prepare electrode buffer, and add to lower reservoir as in Section 6.1. Place the centralcooling core in the lower chamber, and add electrode buffer to the upper reservoir cham-ber.2.The sample may be loaded with an Eppendorf-type pipettor, with a needle and syringe,or with a Hamilton syringe. Start at one end of the gel, and deliver the sample gently andevenly over the entire length of the gel. Layer the sample as closely as possible (1-2 mm)to the surface of the gel.6.3 Gels as SamplesAll two-dimensional techniques involve this variation of sample loading. Either a cylin-drical gel or a strip of a slab gel may be placed on top of a slab gel for separation into a sec-ond dimension. This procedure is described in detail in Section 10.Section 7Running the Gel1.Place the lid on top of the lower buffer chamber to enclose the PROTEAN II xi cell fully.Note that the lid can be placed only in one orientation, so that the anode and cathode con-nections cannot be reversed.2.Attach the electrical leads to a suitable power supply, such as those in Section 13.6,with the proper polarity (this connection could accidently be reversed).3.Apply power to the PROTEAN II xi cell and begin electrophoresis. As a safety pre-caution, always set voltage, current, and power limits when possible. See the Appendix(Section 14.4) for specific running conditions.。
ANAFI USA商品说明书
ANAFI USADesigned for the U.S. Army.Made for Enterprise.Made in USA. Blue sUAS program approved. NDAA & TAA compliant.COMPATIBLE PARTNER SOFTWARE SUITE PIX4Dcapture, PIX4Dinspect, PIX4Dcloud, PIX4Dreact, PIX4Dsurvey, DroneSense,DroneLogbook, Survae, High Lander, QGroundControl, Hoverseen, Textron Systems.TRUSTED & PROVEN GLOBALLYThermal camera Detect centimetric hot spot from an altitude of up to 40 m (131 ft)Flight Flight ready in 55 sZero no fly zone limitation TA The largest ecosystem for drones Extend your professional usage Observe people 32x zoom from up to 2 km (1.2 mi) awayParrot believes that drones are usefulfor everyday business. They must be easyto use and adaptable to complex missions.ANAFI USA ANAFI USA GOV ANAFI USA MIL Pack content• 1 ANAFI USA drone• 3 smart batteries (3x32 minutes)• 1 Skycontroller 3• 1 tablet holder• 1 multi-port fast USB charger • 1 additional set of propeller blades • 4 USB-A/USB-C cables• 1 hard case • 1 ANAFI USA drone• 3 smart batteries (3x32 minutes)• 1 Skycontroller USA with its 8-inch display• 1 multi-port fast USB charger• 1 Skycontroller USA charger• 1 additional set of propeller blades• 3 USB-A/USB-C cables• 1 USB-C/USB-C cable• 1 hard case• 1 sunvisor• 1 neck strap• 1 ANAFI USA drone• 3 smart batteries (3x32 minutes)• 1 Skycontroller USA with its 8-inch display• 1 multi-port fast USB charger• 1 Skycontroller USA charger• 1 additional set of propeller blades• 3 USB-A/USB-C cables• 1 USB-C/USB-C cable• 1 hard case• 1 sunvisor• 1 neck strap• AES 256 encrypted Microhard radiocommunication system• TOGA (Tactical Open GovernmentArchitecture) compatibleAdditional software features• Disabling the auto-RTH function tomaximize airtime and range• Importing KML and TMS map tiles forup-to-date and optimal situation awareness • Disabling the auto-RTH function tomaximize airtime and range• Importing KML and TMS map tiles forup-to-date and optimal situation awareness • 15 frames per second for increasedthermographic precisionCertifications• IP53 certified (dust and rain resistant)• NDAA & TAA compliant• Blue sUAS program approved • IP53 certified (dust and rain resistant)• NDAA & TAA compliant• Blue sUAS program approved• IP53 certified (dust and rain resistant)TECHNICAL SPECIFICATIONSDRONE• Weight: 496 g / 1 lb.• Maximum take-off mass (MTOM): 644 g / 1.42 lb.• Maximum transmission range: 5 km (3.1 mi)• Maximum flight time: 32 minutes(30 minutes with optional Microhard mounted)• Maximum horizontal speed: 15 m/s• Maximum vertical speed: 4 m/s• Maximum wind resistance: 15 m/s• Maximum propeller speed: 11,000 rpm• Sound power level at 1 m (3 ft): 84 dB• Service ceiling: 5,000 m above MSL(Mean Sea Level)• Optional altitude fencing & geofencing• IP53 certified: dust and rain resistant• Operating temperature: -32 °F (-35 °C)to +120 °F (+49 °C)• No take-off temperature limitation• No NFZ (no-fly zone) limitation• Takes off from / lands in the hand of the operator SECURITY• Manage your data privately between droneand device ORshare anonymous data on secured European servers • MicroSD card encryption:- LUKS2 volume with AES-XTS protocol- 512 bits key• WPA2 AES CCMP encrypted network connections • Digitally signed authenticated firmware DIMENSIONS• Size folded: 252x104x82 mm• Size unfolded: 282x373x84 mm• Size unfolded with optional Microhard:282x373x192 mmSENSORS• Satellite navigation: GPS, GLONASS & GALILEO • Barometer and magnetometer• Vertical camera and ultra-sonar• 2 x 6-axis IMU• 2 x 3-axis accelerometers• 2 x 3-axis gyroscopesEO IMAGE CHAIN• 2 sensors: 1/2.4’’• Digital zoom: 32x• Electronic shutter speed: 1 s to 1/10,000 s• ISO range: 100-3200• Video resolution: 4K/FHD/HD• Video format: MP4 (H.264)• Photo resolutions:- Wide: 21 MP (84° FOV);- Rectilinear: up to 16 MP (up to 75.5° FOV)• Photo formats: JPEG, DNG (Digital NeGative RAW) IR IMAGE CHAINSensor: FLIR BOSON• 320x256 resolution• -40 °C to +150 °C temperature range• Thermal sensitivity: <60 mK• Measured IR wavelength range: 7.5 to 13 micrometers • Photo format: JPEG• Video format: MP4 (H.264)• Video recording resolution: 1280x720• Framerate: 9 fps (15 fps for ANAFI USA MIL)IMAGE STABILIZATION• 3-camera IR/EO stabilized gimbal:- Hybrid: 3-axis- Mechanical: 2-axis roll / pitch- Electronics (EIS): 3-axis pitch / roll / yaw• Controllable gimbal tilt range: -90° to +90°FAST-CHARGING SMART BATTERY• Type: High density LiPo (3 x 4.4 V cells)• Capacity: 3,400 mAh• Battery life: 32 minutes• Charging port: USB-C• Charges in 2h with a USB-PD (Power Delivery) charger • Weight: 195 g / 0.43 lb.• Voltage: 11.55 V• Max charging power: 30 WPARROT SKYCONTROLLER 3• Size folded: 94x152x72 mm• Size unfolded: 153x152x116 mm• Weight: 283 g / 0.62 lb• Transmission system: Wi-Fi 802.11a/b/g/n(Wi-Fi beacon)• Operating frequencies: 2.4 - 5.8 GHz• Max. transmission distance: 4 km / 2.48 mi• Resolution of live video feed: HD 720p• Battery capacity: 2,500 mAh 3.6 V• Battery life: 2h30 (Android) / 5h30 (iOS)• Compatible mobile devices: screen size up to 10”• USB ports: USB-C (charge), USB-A (connection) PARROT SKYCONTROLLER USA• Size: 313x208x72 mm• Size with optional Microhard: 313x208x173 mm• Weight: 1.25 kg / 2.76 lbs.• TAA & NDAA compliant• Transmission system: Wi-Fi 802.11a/b/g/n(Wi-Fi beacon)• Operating frequencies: 2.4 - 5.8 GHz• Max. transmission distance: 5 km / 3.1 mi• Resolution of live video feed: HD 720p• 2h charging time for 4h30 battery life• Based on the 8’’ Samsung Galaxy Tab A (2019)• IP53 certified: dust and rain resistantANAFI USA MIL MICROHARD• Model: pDDL1800 1.8 GHz• TOGA (Tactical Open Government Architecture)compatible• Foldable antennas• Range: 5 km / 3.1 mi• AES 256 encryption• Additional weight:- 25 g on ANAFI USA- 40 g on the Skycontroller USA。
PROKoZ Surflan产品说明书
1.PRODUCT AND COMPANY IDENTIFICATIONProduct Name PROKoZ Surflan AS Specialty EPA Reg #70506-44Recommended Use herbicide Product Code12U-125CIssued Date 03-Jul-2009Available Hrs UPIMaterial Safety Data SheetCustomer Service R&D Technical ServiceRevision Date 1-800-438-6071610-878-61008:00 am to 5:00 pm EST 8:00 am - 5:00 pm (EST)Revision Number: 0PPEUPI630 Freedom Business Center Suite 402King of Prussia,PA 19406Emergency Telephone NumberChemtrec: (800) 424-9300 (24hrs) or (703) 527-3887Medical: Rocky Mountain Poison Control Center (866) 673-6671 (24hrs)Company InformationNFPAContact Information Phone Number2. HAZARDS IDENTIFICATIONPotential Health Effects- Inhalation - Skin contact- Repeated or long term exposure may cause adverse effects on the liver or thyroid.- Propylene glycol symptoms may include central nervous system depression, headache, dizziness, drowsiness and loss of coordination.3. COMPOSITION/INFORMATION ON INGREDIENTSIngredients NameChemical NameCAS-No Weight %OSHA PELOryzalin 19044-88-340.9N/AGlycerin56-81-5<30 5 mg/m³ Respirable fraction.10 mg/m³ Total dust.Propylene Glycol57-55-6<40N/A4. FIRST AID MEASURESEye ContactHold eye open and rinse slowly and gently with water for 15 - 20 minutes. Remove contact lenses, if present, after 5 minutes, then continue rinsing eye.Call a poison control center or doctor for treatment advice.Skin ContactTake off contaminated clothing.Wash off immediately with plenty of water for at least 15 minutes If skin irritation persists, call a physicianInhalationMove person to fresh air.If person is not breathing, call 911 or an ambulance, then give artifical respiration.Call a poison control center or doctor for further treatment advice.IngestionCall a physician or Poison Control Center immediately Never give anything by mouth to an unconscious personDo not induce vomiting unless told to do so by a poison control center or doctorNotes to PhysicianNo information availableCAUTIONEmergency OverviewMay cause eye and skin irritationProlonged skin contact may cause local redness. May cause an allergic reaction in sensitive individuals.May cause irritation to the respiratory tract.Odor Slight. Aromatic.Appearance Opaque, Orange.Physical State Liquid.5. FIRE-FIGHTING MEASURESFlammable Explosive PropertiesFlash Point> 93°C> 200°F Autoignition Temperature Not applicableFlammability Limits in AirNot availableExtnguishing MediaUse extinguishing measures that are appropriate to local circumstances and the surrounding environmentFire/Explosion HazardThis material will become a fire hazard only when a sufficient amount of water has evaporated. At that point, the material will exhibit the flammability characteristics of propylene glycol and oryzalin. The explosive potential of oryzalin as an airborn dust is rated severe. The minimum ignition temperature for a dust cloud is 714 F (379 C).Hazardous Combustion ProductsOxides of nitrogen, Can emit toxic fumes under fire conditions.6. ACCIDENTAL RELEASE MEASURESPersonal PrecautionsAvoid contact with the skin and the eyes. Use personal protective equipment.Environmental PrecautionsConsult a regulatory specialist to determine appropriate state or local reporting requirements, for assistance in waste characterization and/or hazardous waste disposal and other requirements listed in pertinenet environmental permits..Methods for Clean-upSoak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust). Sweep up and shovel into suitable containers for disposal.7. HANDLING AND STORAGEHandlingKeep out of reach of children. Do not eat, drink or smoke when using this product. Avoid contact with skin and eyes. Wear personal protective equipment.StorageKeep container tightly closed in a dry and well-ventilated place.8. EXPOSURE CONTROLS / PERSONAL PROTECTIONExposure GuidelinesChemical NameACGIH TLV OSHA PELGlycerin10 mg/m 3 Mist.5 mg/m³ Respirable fraction.10 mg/m³ Total dust.Health 1Flammability 1Instability 0NFPAEngineering ControlsInvestigate engineering techniques to reduce exposures. Local mechanical exhaust ventilation is preferred. Consult ACGIH ventilation manual or NFPA Standard 91 for design of exhaust systems. .Personal Protective Equipment Eye/face Protection Where there is potential for eye contact have eye flushing equipment available.. Use eye protection to avoid eye contact. . Skin Protection Wear protective gloves/clothing.Respiratory ProtectionWhere airborne exposure is likely, use NIOSH approved respiratory protection equipment appropriate to the material and/or its components. Full facepiece equipment is recommended and, if used, replaces need for face shield and/or chemical goggles. If exposures cannot be kept at a minimum with engineering controls, consult respirator manufacturer to determine appropriate type equipment for given application. Observe respirator use limitations specified by NIOSH or the manufacturer. For emergency and other conditions where there may be a potential for significant exposure, use an approved full face positive-pressure, self-contained breathing apparatus. Respiratory protection programs must comply with 29 CFR 1910.134. .General Hygiene ConsiderationsDo not eat, drink or smoke when using this product. Wear suitable gloves and eye/face protection. Wash hands before breaks and immediately after handling the product. Remove and wash contaminated clothing before re-use.9. PHYSICAL AND CHEMICAL PROPERTIES10. STABILITY AND REACTIVITYStabilityStable under recommended storage conditions If water mixtureevaporates the resultant mixture should be handled with care as the explosive potential of oryzalin as an airborne dust is rated severe.Conditions to AvoidAvoid dust formation.Incompatible MaterialsNo materials to be especially mentioned.Hazardous Decomposition ProductsToxic gases and fumes may be formed if product is involved in fire. . Oxides of nitrogen.Possibility of Hazardous PolymerizationHazardous polymerisation does not occur11. TOXICOLOGICAL INFORMATIONAcute ToxicityNot availablePercent VolatilesNot availableMelting Point/Range Not available Odor Slight Aromatic Specific Gravity 1.138 to 1.239 @ 25 C SolubilityMiscibleEvaporation Rate Not available Physical StateLiquidVapor Pressure Not available Appearance Vapor Density Not available Opaque Orange VOC ContentNot available pHapprox.5.9 Viscosity Not available Molecular Weight No data available Bulk DensityNo data available Boiling Point/Range Not availablePercent SolidsComponent Information Oryzalin -In animals has been shown to cause liver, kidney, bladder, spleen, and/or bloodeffects. Repeated excessive exposure to crystalline silica may affect lung functionand cause silicosis, a progressive and disabling disease of the lungs. Someevidence suggests that kidney effects may also result from excessive exposure.Propylene glycol:Single exposure studies indicate that this material is practically non-toxic if swallowed(rat LD50 21,000 mg/kg) or absorbed through skin (rabbit LD50 20,800 mg.kg) andslightly irritating to rabbit eyes and skin.This material is widely used in antifreeze, hydraulic fluids, pharmaceutical solvents,food and cosmetics. Workplace experience has shown this material to have lowacute and systemic toxicity. Human patch tests indicate that repeated contactcauses mild irritation. Although there have been some reports of skin sensitization,studies with large groups of humans and use in topical medical applications suggestthat these are likely irritant rather than sensitization responses.Repeated administration in the diet or through drinking water to rats and dogsshowed essentially no adverse effects other than slight liver toxicity. SImilar studiesin cats showed increase in Heinz body formation in the red blood cells withoutanemia. Long-term oral studies in rats, dogs, and cats have shown no evidence ofcarcinogenic or target organ effects other than increased red blood cell turnover.Long-term inhalationexposure in monkeys showed no adverse effects.Developmental toxicity studies in mice, rats, rabbits and hamsters showed noincreased birth defects or other adverse effects on the fetus. Mice and cats had noadverse effects on reproductive ability or development and survival of offspring. Nogenetic changes were observed in tests using bacteria, animal cells, or animals.Glycerin:No skin allergy was observed in guinea pigs or humans following repeated exposure.Oral administration in clinical use has caused nausea and vomiting. Repeated orlong-term oral exposure produced no adverse effects in rats. No adverse effects onfertility or birth defects were observed in rats or their offspring following oral exposurebefore and during pregnancy. Generally, no genetic changes were observed in testsusing bacteria or animal cells.Single exposure studies indicate that this material is practically non-toxic if swallowed(rat LD50 12,600- 27,200 mg/kg) or absrobed through skin (rabbit LD50 >10,000mg/kg), no more than slightly toxic if inhaled (rat 1 hr LC50 >0.57 mg/l), and slightlyirritating to rabbit eyes and skin.Chronic ToxicityCarcinogenicity Thyroid follicular cell tumors observed in rats were considered a secondary response caused by mechanisms not relevant to humans. Benign skin and adnexal tumors observed in rats may also have been secondary to thyroid effects.In vitro and animal mutagenicty studies on oryzalin and propylene glycol werew negative..12. ECOLOGICAL INFORMATIONEcotoxicityOryzalin -Bioconcentration potential is low (BCF <100 or low Pow <3)Degradation is expected in the soil environment within days to weeks.Material is highly toxic to aquatic organisms on an acute basis (LC50/EC50 between 0.1 and 1 mg/L in most sensitive species). Material is slightly toxic to birds on an acute basis (LD50 is between 501 and 2000 mg/kg.Acute oral LD50 in bobwhite (Colinus virginianus) is 1046 mg/kg.Acute oral LD50 in honeybee (Apis mellifera) is >100 ug..13. DISPOSAL CONSIDERATIONSWaste Disposal Method Pesticide wastes are acutely hazardous. Improper disposal of excess pesticide or rinsate is aviolation of Federal law. If the wastes cannot be disposed of by use or according to labelinstructions, contact your State Pesticide or Environmental Control Agency, or the HazardousWaste representative at the nearest EPA Regional Office for guidance. . Do not dischargeeffluent containing this product into lakes, streams, ponds, estuaries, oceans, or other watersunless in accordance with the requirements of a National Pollutant Discharge EliminationSystem (NPDES) permit. Do not discharge effluent containing this product to sewer systemswithout previously notifying the local sewage treatment plant authority. Do not apply directly towetlands or water..Contaminated Packaging Empty containers should be taken for local recycling, recovery or waste disposal14. TRANSPORT INFORMATIONDOTWhen shipped in bulk use IMDG shipping descriptionICAO Not regulatedIATA Not regulatedIMDG/IMOProper Shipping Name Environmentally hazardous substances, liquid, n.o.s. (Oryzalin)Class9HazardUN-No UN3082Group PG IIIPackingPollutant YesMarine15. REGULATORY INFORMATIONInternational InventoriesOryzalinUSAFederal RegulationsSARA 313YChemical NameCAS-No Weight %Oryzalin19044-88-340.9SARA 311/312 Hazardous Categorization Chronic Health Hazard NoAcute Health Hazard Yes Fire Hazard No Sudden Release of Pressure Hazard No Reactive HazardNoClean Water ActClean Air Act, Section 112 Hazardous Air Pollutants (HAPs) (see 40 CFR 61) This product contains the following HAPs:Chemical Name CAS-No Weight %HAPS dataVOC Chemicals Class 1 Ozone DepletorsClass 2 Ozone DepletorsGlycerin 56-81-5<30Listed.Propylene Glycol57-55-6<40Listed.CERCLA RCRAPesticide InformationState RegulationsCalifornia Proposition 65This product does not contain any Proposition 65 chemicals.Listed Oryzalin ENCS Listed KECL Listed CHINA Listed KECL Listed Glycerin Propylene Glycol DSL Listed EINECS/ELINCS EINECS/ELINCS Listed DSL Listed ENCS Listed Listed CHINA Listed EINECS/ELINCS KECL ListedState Right-to-KnowChemical Name Massachusetts New Jersey Pennsylvania Illinois Rhode Island Glycerin Listed.Listed.Listed.Listed.Propylene Glycol Listed.Listed.International RegulationsMexico - Grade Not availableChemical Name Category Carcinogen Status Exposure Limits Glycerin10 mg/m³ Mist.CanadaThis product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all the information required by the CPR.WHMIS Hazard ClassNot determined16. OTHER INFORMATIONRevision DateRevision SummaryAdd to systemUPI, Inc. believes that the information and recommendations container herein (including data and statements) are accurate as of the date hereof. NO WARRANTY OF FITNESS FOR ANY PARTICULAR PURPOSE, WARRANTY OF MERCHANTABILITY, OR ANY OTHER WARRANTY, EXPRESSED OR IMPLIED, IS MADE CONCERNING THE INFORMATION PROVIDED HEREIN. The information provided herein relates only to the specific product designated and may not be valid where such product is used in combination with other materials or in any process. Further, since the conditions and methods of use are beyond the control of UPI, Inc. UPI, Inc. expressly disclaims any and all liability as to any results obtained or arising from any use of the product or reliance on such information.End of MSDS。
自然卫士Spinosad产品安全数据表说明书
Natural Guard® Spinosad Voluntary Purchasing Groups, Inc. 230 FM 87Bonham, Texas 75418Effective Date: December 12, 20081. PRODUCT AND COMPANY IDENTIFICATION:PRODUCT: Natural Guard SpinosadEPA No.: 62719-314-7401COMPANY IDENTIFICATION:Voluntary Purchasing Groups, Inc.230 FM 87Bonham, Texas 754182. HAZARDOUS IDENTIFICATIONS:EMERGENCY OVERVIEWOff-White to tan liquid suspension with low odor. May cause slight eye irritation. Material is slightly toxic to aquatic organisms.EMERGENCY PHONE NUMBER: 800-424-93003. COMPOSITION/INFORMATION ON INGREDIENTS:COMPONENT CASNUMBERW/W%Spinosad: Spinosyn A 131929-60-7 0.5%Spinosyn D 131929-63-0 2.0Balance, Total, Including:Propylene glycol(1,2-Propanediol)000057-55-6 99.5%4. FIRST AID:EYE: Hold eyes open and rinse slowly and gently with water for 15-20 minutes. Remove contact lenses, if present, after the first 5 minutes, and then continue rinsing eyes. Call a poison control center or doctor for treatment advice.SKIN: Take off contaminated clothing. Rinse skin immediately with plenty of water for 15-20 minutes. Call a poison control center or doctor for treatment advice.INGESTION: Call a poison control center or doctor immediately for treatment advice. Have person sip a glass of water if able to swallow. Do not induce vomiting unless told to do so by the poison control center or doctor. Never give anything by mouth to an unconscious person.INHALATION: Move person to fresh air. If person is not breathing, call 911 or ambulance, and then give artificial respiration, preferably by mouth to mouth. Gall a poison control center or doctor for further treatment advice.NOTE TO PHYSICIAN: No specific antidote. Treatment of exposure should be directed at the control of symptoms and the clinical condition of the patient.5. FIRE FIGHTING MEASURES:FLASH POINT: Not determined (aqueous suspension)METHOD USED: Not applicableFLAMMABLE LIMITS:LFL: Not determined (water-based product)UFL: Not determined(water-based product)Natural Guard® Spinosad Voluntary Purchasing Groups, Inc. 230 FM 87Bonham, Texas 75418Effective Date: December 12, 2008EXTINGUISHING MEDIA: To extinguish combustible residues of this product use water fog, carbon dioxide, dry chemical or foam.FIRE AND EXPLOSION HAZARDS: Keep people away. Isolate fire and deny unnecessary entry. Under fire conditions some components of this produce may decompose. The smoke may contain unidentified toxic and/or irritating compounds.FIRE-FIGHTING EQUIPMENT: Wear positive-pressure, self-contained breathing apparatus (SCBA) and protective fire-fighting clothing (includes fire-fighting helmet, coat, pants, boots and gloves). If protective equipment is not available or not used, fight fire from a protected location or safe distance.6. ACCIDENTAL RELEASE MEASURES:ACTION TO TAKE FOR SPILLS: Use non-reactive absorbent to absorb small spills and collect for disposal. Report large spills to CHEMTREC 800-424-93007. HANDLING AND STORAGE:PRECAUTIONS TO BE TAKEN IN HANDLING AND STORAGE: Keep out of reach of children. Avoid eye contact. Do not take internally. Wash thoroughly after handling and before eating, drinking, or smoking. Store product in original container. See product label for additional instructions.8. EXPOSURE CONTROLS/PERSONAL PROTECTION:These precautions are suggested for conditions where the potential for exposure exists. Emergency conditions may require additional precautions.EXPOSURE GUIDELINES: Propylene glycol: AIHA WEEL is 10 mg/ M3 for total vapor and aerosol.Spinosad: Voluntary Purchasing Groups Industrial Hygiene Guide is 0.3 mg/ M3, TWA.ENGINEERING CONTROLS: Provide general and/or local exhaust ventilation to control airborne levels below the exposure guidelines.RECOMMENDAITONS FOR MANUFACTURING, COMMERCIAL BLENDING, AND PACKAGINGWORKERS:EYE/FACE PROTECTION: Use of safety glasses is recommendSKIN PROTECTION: Use gloves chemically resistant to this material when prolonged or frequently repeated contact could occur.RESPIRATORY PROTECTION: Atmospheric levels should be maintained below the exposure guideline. APPLICATORS AND ALL OTHER HANDLERS: Refer to the product label for personal protective clothing and equipment.9. PHYSICAL AND CHEMICAL PROPERTIES:APPEARANCE: Off-white to light tanODOR: Low odorBOILING POINT: 100°C C (212F) waterPHYSICAL STATE: Liquid suspensionNatural Guard® Spinosad Voluntary Purchasing Groups, Inc. 230 FM 87Bonham, Texas 75418Effective Date: December 12, 2008VAPOR PRESSURE: similar to waterSOLUBILITY IN WATER: DispersibleDENSITY: 1.09 g/ml10. STABILITY AND REACTIVITY:STABILITY: (CONDITIONS TO AVOID) Thermally stable at typical use temperatures. Some components of this product can decompose at elevated temperatures.INCOMPATIBILITY: (SPECIFIC MATERIALS TO AVOID) None known.HAZARDOUS DECOMPOSITION PRODUCTS: Hazardous decomposition products depend upon temperature, air supply and the presence of other materials.HAZARDOUS POLYMERIZATION: Not known to occur.11. TOXICOLOGICAL INFORMATION:POTENTIAL HEALTH EFFECTS: This section includes possible adverse effects, which could occur if this material is not handled in the recommended manner.EYE: May cause slight eye irritation. Corneal injury is unlikely. May cause pain disproportionate to the level of irritation to eye tissues.SKIN: Prolonged contact may cause slight skin irritation with local redness. The LD50 for skin absorption in rabbits is >5,000 mg/kg. Prolonged skin contact is unlikely to result in absorption of harmful amounts. Did not cause allergic skin irritation or reactions when tested in guinea pigs.INGESTION: Very low toxicity if swallowed. Harmful effects not anticipated from swallowing small amounts. The oral LD50 for rats is >5,000 mg/kg.INHALATION: No adverse effects are anticipated for single exposure to mist. The aerosol LC50 for rats is >.50 mg/L for 4 hours (limit test).SYSTEMIC (OTHER TARGET ORGAN) EFFECTS: Repeated exposure did not produce systemic toxicity when applied to the skin of rabbits.CANCER INFORMATION: Did not cause cancer in laboratory animals.TERATOLOGY (BIRTH DEFECTS): Spinosad did not cause birth defects in laboratory animals.REPRODUCTIVE EFFECTS: Spinosad, in laboratory animal studies, effects on reproduction have been seen only at doses that produced significant toxicity to the parent animals.Mutagenicity: For spinosad, in-vitro and animal mutagenicity studies were negative.12. ECOLOGICAL INFORMATION:ENVIRONMENTAL FATE::MOVEMENT & PARTITIONING:Based largely or completely on information for spinosad.Bioconcentration potential is low (BCF >100 or Log Pow >3). Based on information for spinosyn A.Bioconcentration factor (BCF) in fish is 33.Natural Guard® Spinosad Voluntary Purchasing Groups, Inc. 230 FM 87Bonham, Texas 75418Effective Date: December 12, 2008DEGRADATION AND PERSISTENCE:Based largely or completely on information for spinosad.Based on information for spinosyn A.The photolysis half-life in pH7 buffer is 0.96 days.Under aerobic soil conditions the half-life is 9.4 and 17.3 days.Based on information for spinosyn D.The photolysis half-life in soil is 9.44 days.The photolysis half-life in pH7 buffer is 0.84 days.ECOTOXICOLOGY:Material is slightly toxic to aquatic organisms on an acute basis (LC50/EC50 between 10 and 100 mg/L in most sensitive species.Acute immobilization EC50 in water flea (Daphnia magna) is 16.9 mg/L.Acute LC50 in water flea (Daphnia magna) is >90.9 mg/L.Acute LC50 in zebra fish (Brachydanio rerio) is >120 mg/L.Acute LC50 in common carp (Cyprinus carpio) is >100mg/L.The LC50 in earthworm (Eisenia foetida) is >2000 mg/kg.Growth inhibition EC50 in diatom (Navicula sp.) is 0.667 mg/L.Growth inhibition EC50 in green alga (Selenastrum capricornutum) is >100 mg/L.Acute contact LC50 in honeybee (Apis mellifera) is 0.12 ug/bee.Acute oral LD50 in honeybee (Apis mellifera) is .011 ug/bee.13 DISPOSAL CONSIDERATIONS:DISPOSAL METHOD: If wastes and/or containers cannot be disposed of according to the product label directions, disposal of this material must be in accordance with your local or area regulatory authorities. This information presented below only applies to the material as supplied. The identification based on characteristics(s) or listing may not apply if the material has been used or otherwise contaminated. It is the responsibility of the waste generator to determine the toxicity and physical properties of the material generated to determine the proper waste identification and disposal methods in compliance with applicable regulations. F the material as supplied becomes a waste, follow all applicable regional, national and local laws and regulations.14. TRANSPORT INFORMATION:U.S. DEPARTMENT OF TRANSPORTATION (DOT) INFORMATION:For all package sizes and modes of transportation:This material is not regulated for transport.15. REGULATORY INFORMATION:NOTICE: The information herein is presented in good faith and believed to be accurate as of the effective date shown above. However, no warranty, express or implied, is given. Regulatory requirements are subject to change and may differ from one location to another; it is the buyer’s responsibility to ensure that its activities comply with federal, state or provincial, and local laws. The following specific information is made for the purpose of complying with numerous federal, state or provincial, and local laws and regulations.U.S. REGULATIONSSARA 313 INFORMATION: To the best of our knowledge, this product contains no chemical subject to SARA Title III Section 313 supplier notification requirements.Natural Guard® Spinosad Voluntary Purchasing Groups, Inc. 230 FM 87Bonham, Texas 75418Effective Date: December 12, 2008SARA HAZARD CATEGORY: This product has been reviewed according to the EPA “Hazard Categories” promulgated under Sections 311 and 312 of the Superfund Amendment and Reauthorization Act of 1986 (SARA Title III) and is considered, under applicable definitions, to meet the following categories:An immediate health hazardTOXIC SUBSTANCES CONTROL ACT (TSCA): All ingredients are on the TSCA inventory or are not required to be listed on the TSCA inventory.STATE RIGHT-TO-KNOW: The following product components are cited on certain state lists as mentioned. Non-listed components may be shown in the composition section of the MSDS.CHEMICAL NAME CASE NUMBER LIST1,2-Propanediol 000057-55-6 PA1PA1=Pennsylvania Hazardous Substance (present at >or = to 1.0%.OSHA HAZARD COMMUNICATION STANDARD: This product is a “Hazardous Chemical” as defined by the OSHA Hazard Communication Standard, 29 CFR 1910.1200.COMPREHENSIVE ENVIRONMENTAL RESPONSE COMPENSATION AND LIABILITY ACT (CERCLA,OR SUPERFUND): To the best of our knowledge, this product contains no chemical subject to reporting under CERCLA.。
Perkadox 14-40MB-GR-S 商品数据表说明书
Product Data SheetPerkadox 14-40MB-GR-S Di(tert-butylperoxyisopropyl) benzenePerkadox® 14-40MB-GR-S is a 40% inert polymer bound formulation in granular form.CAS number2212-81-9, 25155-25-3EINECS/ELINCS No.218-664-7TSCA statuslisted on inventoryMolecular weight338.5Active oxygen contentperoxide9.45%Concentration3.7-3.9%SpecificationsAppearance Off-white flexible granulesAssay39.0-41.0 %ApplicationsPerkadox® 14-40MB-GR-S is a bifunctional peroxide which is used for the crosslinking of natural rubber and synthetic rubbers, as well as polyolefins. Rubber compounds containing Perkadox® 14-40MB-GR-S have excellent scorch safety, and under certain conditions one step mixing is possible. Safe processing temperature: 135°C (rheometer ts2 > 20 min.). Typical crosslinking temperature: 175°C (rheometer t90 about 12 min.)Thermal stabilityOrganic peroxides are thermally unstable substances, which may undergo self-accelerating decomposition. The lowest temperature at which self-accelerating decomposition of a substance in the original packaging may occur is the Self-Accelerating Decomposition Temperature (SADT). The SADT is determined on the basis of the Heat Accumulation Storage Test.SADT80°CMethod The Heat Accumulation Storage Test is a recognized test method for thedetermination of the SADT of organic peroxides (see Recommendations on theTransport of Dangerous Goods, Manual of Tests and Criteria - United Nations, NewYork and Geneva).StorageDue to the relatively unstable nature of organic peroxides a loss of quality can be detected over a period of time. To minimize the loss of quality, Nouryon recommends a maximum storage temperature (Ts max. ) for each organic peroxide product.Ts Max.30°CNote When stored under these recommended storage conditions, Perkadox® 14-40MB-GR-S will remain within the Nouryon specifications for a period of at least 6months after delivery.Packaging and transportThe standard packaging is a cardboard box for 25 kg peroxide formulation. Both packaging and transport meet the international regulations. For the availability of other packed quantities contact your Nouryon representative. Perkadox®14-40MB-GR-S is classified as Flammable solid, class 4.1, UN 1325.Safety and handlingKeep containers tightly closed. Store and handle Perkadox® 14-40MB-GR-S in a dry well-ventilated place away from sources of heat or ignition and direct sunlight. Never weigh out in the storage room. Avoid contact with reducing agents (e. g. amines), acids, alkalis and heavy metal compounds (e. g. accelerators, driers and metal soaps). Please refer to the Safety Data Sheet (SDS) for further information on the safe storage, use and handling of Perkadox® 14-40MB-GR-S. This information should be thoroughly reviewed prior to acceptance of this product. The SDS is available at /sds-search.Major decomposition productsMethane, Acetone, tert-Butanol, Di(2-hydroxyisopropyl)benzene, Diacetylbenzene, Acetyl 2-hydroxyisopropyl benzeneAll information concerning this product and/or suggestions for handling and use contained herein are offered in good faith and are believed to be reliable.Nouryon, however, makes no warranty as to accuracy and/or sufficiency of such information and/or suggestions, as to the product's merchantability or fitness for any particular purpose, or that any suggested use will not infringe any patent. Nouryon does not accept any liability whatsoever arising out of the use of or reliance on this information, or out of the use or the performance of the product. Nothing contained herein shall be construed as granting or extending any license under any patent. Customer must determine for himself, by preliminary tests or otherwise, the suitability of this product for his purposes.The information contained herein supersedes all previously issued information on the subject matter covered. The customer may forward, distribute, and/or photocopy this document only if unaltered and complete, including all of its headers and footers, and should refrain from any unauthorized use. Don’t copythis document to a website.Perkadox® is a registered trademark of Nouryon Functional Chemicals B.V. or affiliates in one or more territories.Contact UsPolymer Specialties Americas************************Polymer Specialties Europe, Middle East, India and Africa*************************Polymer Specialties Asia Pacific************************2022-6-30© 2022Polymer crosslinking Perkadox 14-40MB-GR-S。
Parker Hannifin Corporation Sporlan Division - P-S
Parker Hannifin CorporationSporlan Division - Refrigeration Business Unit 2445 South 25th AvenueBroadview, IL 60155-3891 USA Phone: (708) 681-6300Fax: (708) 681-6306ISO 9001 CERTIFIED1234112341234X4X4X4Discard5OperationPrior to installing the P-Series Electronic Valve (PEV) the included safety bulletins must be read and understood.ENGLISHRefrigerantsSuitable for ammonia, CO 2, and other common refrigerantsLiquid Temperature Range -60ºC to 120ºC (-76ºF to 248ºF)Ambient Temperature Range -40ºC to 50ºC (-40ºF to 122ºF)Maximum Rated Pressure (MRP)52 barg (754 psig)Maximum Operating Pressure Differential (MOPD)Figure 1: Components 1 - Port Plate Assembly 2 - Bolts, Port Plate 3 - Valve Body4 - Gasket, Port Plate (New)PortBolt Size Nm Ft Lb 20 mm (3⁄4”) to 25 mm (1”)M12 x 1.75614532 mm (11⁄4”) to 40 mm (11⁄2”)M16 x 2149110Figure 5: Re-Assembly1 - Gasket, Port Plate (New)InstallationAll personnel working on valves must be qualified to work on refrigeration systems. If there are any questions contact Sporlan Division - Refrigeration Business Unit before proceeding with the work.All valves are packed for a maximum protection. Unpack carefully. Check the carton to make sure all items are unpacked, see Figure 1 for the list of items included. Do not remove the protective coverings from the inlet and outlet of the valve until the valve is ready to be installed. Protect the inside of the valve from dirt and chips before and during installation. In the event the valve is left disassembled for any length of time, protecting the components is essential. Place the components in a plastic bag and store them in an area where they will not be damaged.The valve should be installed in a location where it is easily accessible foradjustment and maintenance. The location should be such that the body cannot be easily damaged by material handing equipment. Proper indicating gauges should be installed to be easily visible to the operating engineer for system checks and adjustment purposes.The valve should be disassembled before welding to prevent damage to o-rings and teflon (PTFE) components. First remove the port plate by unbolting the bolts as shown in Figure 2. If the port plate does not come apart easily, rotate the port plate 45º and use the corners to pry the port plate out. If using a tool, such as a screw driver, it is important to be careful not to damage any gasket surfaces.The current port plate gasket must be removed, as shown in Figure 3, anddiscarded. A replacement gasket is provided with every purchase of a new valve.The PEV valves must be mounted in the upright horizontal position with the actuator on the top. The valve must be installed with the arrow pointing in the direction of flow for the valve to function properly.Installers need to follow a WPS (Welding Procedure Specification) for all welding. The procedure and welder doing the weld must be qualified to perform that procedure.The codes applicable to the welding of socket weld valves require that the pipe be inserted into the socket until bottomed against the stop, then backed out approximately 1⁄16 of an inch (1.6 mm) before welding. Use of welding rings isoptional but recommended for butt weld valves. They help alignment, control gap for full penetration welding, and reduce welding debris entry.Figure 6: Port Plate Torque SpecsPort MOPD 20 mm (3⁄4”) to 25 mm (1”)52 bard (754 psid)32 mm (11⁄4”) to 40 mm (11⁄2”)28 bard (406 psid)Connection TypesSW, BW ANSI, and BW Metric (DN)P/N 313906RSD B Date: 11-20 ECO: 0345229Parker Electronic Valve (PEV)Installation InformationWARNING – USER RESPONSIBILITY。
(±)8(9)-EET MaxSpec® Standard GlpBio
Product Data SheetProduct Name:(±)8(9)-EET MaxSpec® StandardCat. No.:GC40441Chemical PropertiesCas No.N/AChemicalNameN/ACanonicalSMILESCCCCC/C=C\C/C=C\C[C@@H](O1)[C@@H]1C/C=C\CCCC(O)=OFormula C20H32O3M.Wt320.5 Solubility Soluble in DMSO Storage Store at -20°CGeneral tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request.StructureBackground(±)8(9)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid . (±)8(9)-EET is a major cytochrome P450 (CYP450) metabolite in the renal cortex. It activates PPARα in HEK293 cells when used at a concentration of 1 µM but inhibits NF-κB activity induced by IL-1β in a PPARα-dependent and -independent fashion. It is also a substrate of COX-1 and COX-2, as measured by oxygen consumption and product formation assays when used at a concentration of 50 µM. (8S,9R)-EET (1 µg/kg), but not (8R,9S)-EET, reduces the glomerular filtration rate (GFR) through COX-dependent pre-glomerular vasoconstriction in rats.(±)8(9)-EET MaxSpec® standard is a quantitative grade standard of (±)8(9)-EET that has been prepared specifically for mass spectrometry or any application where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This (±)8(9)-EET MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stabilitytesting is performed to ensure the concentration remains accurate throughout the shelflife of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage andhandling conditions to maintain product quality.。
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Product Name:
Capadenoson CAS No.:
544417-40-5Product Data Sheet
Cat. No.:
HY-14917MWt:
520.03Formula:
C25H18ClN5O2S2Purity :
>98%
Solubility:Mechanisms:
Biological Activity:
Pathways:GPCR/G protein; Target:Adenosine Receptor DMSO
g y
Capadenoson (BAY 68-4986) is a new adenosine A1 receptor agonist.
IC50 value:
Target: adenosine A1 receptor Studies showed that long-term therapy with Capadenoson improves phosphorylation and total
protein level of PGC-1α in LV myocardium of HF dogs. Clinical trial found that in patients with stable angina Capadenoson lowers exercise HR at comparable maximum workload, which is associated with improved total exercise time and prolongation of time to ischaemia.
References:
[1]. Ramesh C. Gupta, et al. Long-term therapy with the partial adenosine A1-receptor agnosit capadenoson, improves peroxisome proliferator-activated receptor coactivator-1α phosphorylation and protein expression in left ventricular myocardium of dogs with chronic heart failure. J Am Coll
Cardiol. 2013;61(10_S).
(_)[2]. Tendera M, et al. The new oral adenosine A1 receptor agonist capadenoson in male patients
with stable angina. Clin Res Cardiol. 2012 Jul;101(7):585-91.[3]. Bott-Flügel L, et al. Selective attenuation of norepinephrine release and stress-induced heart
rate increase by partial adenosine A1 agonism. PLoS One. 2011 Mar 28;6(3):e18048.[4]. Müller CE, et al. Recent developments in adenosine receptor ligands and their potential as novel
drugs. Biochim Biophys Acta. 2011 May;1808(5):1290-308.[5]. Study to Investigate the Effect of the A1 Agonist ...
Caution: Not fully tested. For research purposes only
Medchemexpress LLC
18W i l k i n s o n W a y , P r i n c e t o n , N J 08540,U S A
E m a i l : i n f o @m e d c h e m e x p r e s s .c o m W e b : w w w .m e d c h e m e x p r e s s .c o m。