神经内科英文课件-脑囊虫病
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• affects the brain in 60~90%of cases
Pathogenesis
Food contaminated by eggs of T. solium.
Retrograde infection of proglottid
Anus to oral
Onchosphere in duodenum
• The serum antibody to cyst worm is usually positive using ELISA or Western blot.
• CSF:normal;lymphocyte,pressure,protein increase • CT,MRI:contrast-enhanced mass lesions with
• Initially, treatment may seem to exacerbate neurologic symptoms, with an increase in cells and protein in the CSF.corticoid and mannitol may be useful.
All over the body by blood
circulation
cysticercus cellclosae
Clinical manifestation
1 cerebral parenchyma type:seizures,focal signs,encephalitis
neurologic
leg, and shoulder muscles .
Treatment and prevention
• The usual dose of praziquantel is 50 mg/kg of body weight, given orally daily for 1 5 to 30 days. Albendazole (5 mg/kg tid for 15 to 30 days), an alternative treatment, is believed by some to be more effective.
Cerebral Cysticercosis 脑囊虫病
• In the central and south America and in parts of Africa and the Middle East,south-east Asia.
• This is the larval or intermediate stage of infection with the pork tapeworm T. Solium.
2 subarachnoid space type:headache,hydrocephalus,meningi
3 intraventricle type:Brun’s sign middle foramen of the four ventricle
4 spinal cord type.
Laboratory findings
surrouding edema,intracerebral calcification,ventricular enlargement.
Diagnosis
• History • CT,MRI • antibody • the presence of multiple calcified lesions wenku.baidu.comn the thigh,
• Surgery
Pathogenesis
Food contaminated by eggs of T. solium.
Retrograde infection of proglottid
Anus to oral
Onchosphere in duodenum
• The serum antibody to cyst worm is usually positive using ELISA or Western blot.
• CSF:normal;lymphocyte,pressure,protein increase • CT,MRI:contrast-enhanced mass lesions with
• Initially, treatment may seem to exacerbate neurologic symptoms, with an increase in cells and protein in the CSF.corticoid and mannitol may be useful.
All over the body by blood
circulation
cysticercus cellclosae
Clinical manifestation
1 cerebral parenchyma type:seizures,focal signs,encephalitis
neurologic
leg, and shoulder muscles .
Treatment and prevention
• The usual dose of praziquantel is 50 mg/kg of body weight, given orally daily for 1 5 to 30 days. Albendazole (5 mg/kg tid for 15 to 30 days), an alternative treatment, is believed by some to be more effective.
Cerebral Cysticercosis 脑囊虫病
• In the central and south America and in parts of Africa and the Middle East,south-east Asia.
• This is the larval or intermediate stage of infection with the pork tapeworm T. Solium.
2 subarachnoid space type:headache,hydrocephalus,meningi
3 intraventricle type:Brun’s sign middle foramen of the four ventricle
4 spinal cord type.
Laboratory findings
surrouding edema,intracerebral calcification,ventricular enlargement.
Diagnosis
• History • CT,MRI • antibody • the presence of multiple calcified lesions wenku.baidu.comn the thigh,
• Surgery