Introduction 2014-9

★ Small organic compounds:
Amino acids, Lipids, Sugars, Nucleotides
Metabolism and Regulation synthesis and degradation of organic compounds Transmission and Regulation of Genetic Information DNA RNA Protein
2. Molecular Biology: can be defined as the science concerned with the structure and function of biomacromolecules, and with the transmission and regulation of genetic information.
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Topics
Ⅰ What is(are) Biochemistry & Molecular Biology？
Ⅱ The History of Biochemistry & Molecular Biology
Ⅲ What is(are) Mainly Concerned by Biochemistry & Molecular Biology? Ⅳ The Contents of the Textbook Ⅴ The Importance of Biochemistry & Molecular Biology
DNA
RNA
Protein
3. The relationship between Biochemistry and Molecular Biology：
Molecular Biology is a part of Biochemistry, which has a profound influence on the improvement and progress of Biochemistry.
2. Molecular Biology
The science concerned with the structure and function of biomacromolecules, and with the transmission and regulation of genetic information. （研究核酸、蛋白质等 生物大分子的结构、功能及基因结构、表 达与调控规律的科学）
----Why Should We Learn Biochemistry & Molecular Biology？
Ⅵ How to Learn Well Biochemistry & Molecular Biology?
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1. 叙述生物化学阶段(19世纪末以前)：
主要弄清是什么。例如：弄清了细胞是
wk.baidu.com
生物大分子（Biomacromolecule）
主要指蛋白质（酶）、核酸和聚糖类分子
分子质量一般在104~106之间
其构成遵循共同的规则
由相应的单体构成 这些单体在不同生物中都是相同的 这些单体按一定的顺序首尾相连形成多聚物
单体的排列顺序(sequence)决定着生物大分子的 信息内容
----Why Should We Learn Biochemistry & Molecular Biology？
Ⅵ How to Learn Well Biochemistry & Molecular Biology ?
Aim:Try to Let You Be Interested in Biochemistry &
★ Small organic compounds:
Amino acids, Lipids, Sugars, Nucleotides
Metabolism and Regulation synthesis and degradation of organic compounds Transmission and Regulation of Genetic Information DNA RNA Protein
生命体的基本结构单位；血红蛋白赋予血液
红色；酶是化学反应的主宰；酶的化学本质
是蛋白质等。
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1. Describing Biochemistry (Before 1900s)：
Mainly focus on Describing “what it is”. For
examples (1) Cell is the structural unit of living
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教学设计
推荐网站 ★ http://www.ncbi.nlm.nih.gov/ ★ http://192.168.4.133:8002(生化教研 室网络教学) ★ http://www.biosino.org
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Teaching Design
The Reference Websites
★ http://www.ncbi.nlm.nih.gov/
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1. ★ Biochemistry: can be defined as the science concerned with the chemical basis of life (Gk bios “life”). ★Biochemistry: can also be described as the science concerned with the chemical constituents of living cells and with the reactions and processes they undergo.
Molecular Biology
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Ⅰ What is(are) Biochemistry & Molecular Biology？
1. ★ Biochemistry can be defined as the science concerned with the chemical basis of life (Gk bios “life”). (研究生命的化学基础的科学） ★ The cell is the structural unit of living systems. Thus, biochemistry can also be described as the science concerned with the chemical constituents of living cells and with the reactions and processes they undergo. By this definition, biochemistry encompasses large areas of cell biology, of molecular biology, and of molecular genetics.
2
Teaching Design
Textbook
Xiliang Zha，Libo Yao. Biochemistry & Molecular Biology，8th Ed，People’s Medical Publishing House, 2013
Major Reference Books
1. Yisen Huang, Xiaoyu Hou. Biochemistry & Molecular Biology，3 nd Ed，Science Publishing House，2012 2. Hongti Jia，Zuohua Feng. Biochemistry and Molecular Biology，2nd Ed，People’s Medical Publishing House, 2010 3. Robert K. Murray, Daryl K. Granner, Victor W. Rodwell，Harper‘s Illustrated Biochemistry，27th Ed， McGraw Hill Lange, 2006
某一特定的生物体所拥有的核酸及蛋白质 等生物大分子决定了它的属性。
Chemical Components Biomolecules-----Structure and Function ★ Large organic compounds: (Biomacromolecules) ≥104
DNA, RNA, Protein, polysaccharides (多糖) Proteoglycan(蛋白多糖） Glycoprotein(糖蛋白）
★ Small organic compounds:
Amino acids, Lipids, Sugars, Nucleotides
Metabolism and Regulation synthesis and degradation of organic compounds Transmission and Regulation of Genetic Information
Biochemistry & Molecular Biology
生物化学与分子生物学
Introduction
绪论
Department of Biochemistry & Molecular Biology 生物化学与分子生物学教研室
Fengtian He（何凤田）
Tel:752255
1
教学设计
使用教材
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Chemical Components Biomolecules-----Structure and Function ★ Large organic compounds: (Biomacromolecules) ≥104
DNA, RNA, Protein, polysaccharides (多糖) Proteoglycan(蛋白多糖） Glycoprotein(糖蛋白）
查锡良，药立波 主编，生物化学与分子生物 学，第8版，人民卫生出版社，2013
主要参考书
1. 黄诒森，侯筱宇 主编，生物化学与分子生物 学，第3版，科学出版社，2013 2. 贾弘禔，冯作化 主编，生物化学与分子生物 学, 第2版，人民卫生出版社，2010 3. Robert K. Murray, Daryl K. Granner, Victor W. Rodwell，Harper‘s Illustrated Biochemistry， 27th Ed，McGraw Hill Lange, 2006
目的：激发学习生物化学与分子生物学的兴趣
6
Topics
Ⅰ What is(are) Biochemistry & Molecular Biology？ Ⅱ The History of Biochemistry & Molecular Biology Ⅲ What is(are) Mainly Concerned by Biochemistry & Molecular Biology? Ⅳ The Contents of the Textbook Ⅴ The Importance of Biochemistry & Molecular Biology
★ http://192.168.4.133:8002 (Department
of Biochemistry and Molecular Biology)
★ http://www.biosino.org
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一、什么是生物化学与分子生物学？
二、生物化学与分子生物学发展史
三、生物化学与分子生物学的主要研究内容 四、本书纲要 五、生物化学与分子生物学的重要性 ---为什么要学习(好)生物化学与分子生物学？ 六、如何学好生物化学与分子生物学？
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Chemical Components Biomolecules-----Structure and Function ★ Large organic compounds: (Biomacromolecules) ≥104
DNA, RNA, Protein, Polysaccharides (多糖) Proteoglycan(蛋白多糖） Glycoprotein(糖蛋白）