甜菜碱的功能
合集下载
- 1、下载文档前请自行甄别文档内容的完整性，平台不提供额外的编辑、内容补充、找答案等附加服务。
- 2、"仅部分预览"的文档,不可在线预览部分如存在完整性等问题,可反馈申请退款(可完整预览的文档不适用该条件!)。
- 3、如文档侵犯您的权益，请联系客服反馈,我们会尽快为您处理(人工客服工作时间：9:00-18:30)。
Osmolyte 渗透压调节剂: Protects against dehydration and other types of stress 甜菜碱是最有效的渗透压调节剂，可以帮助保持细胞水分平衡甜菜碱同时也可 以保护细胞的酶不受由于水分流失及有害物质带来的危害 Methyl Donor 甲基供体: Important in many cellular functions 甲基基团参与多过100个与维持肌体及细胞正常功能相关的反应 这些反应包括 DNA、RNA、神经传输物质等的合成，及启动解毒反应 Human Clinical Studies 人体临床研究: •Protect internal organs (heart, liver, kidney) 保护内脏器官 •Improve vascular risk factors (particularly serum homocysteine) 改善与血管疾病相关危险因子的水平 •Enhance physical performance 增强体能
3
Betaine Production and Applications 天然甜菜碱的生产及应用
Sugar beet 甜菜 (0.2-0.3 % betaine)
Methyl donor
Bipolar electrolyte
Sugar beet plant Molasses 糖蜜 (3-6 % betaine) Pulp
Sports performance 运动表现 Betaine is shown in clinical trials to significantly improve strength and power during exercise临床验证表明甜菜碱能显著 提高运动中的力量表现。 Positive benefits for athletes and active people wanting to improve their performance对运动员们有正面的帮助，也能提 高普通人在运动中的表现
Imbalance in glycogen storage and depletion causes blood sugar level fluctuation 糖原的不平衡及过 度损耗将引起血糖波动
Risks associated with toxic build up 毒素堆积 Potential effects on skin and other organs 对皮肤和其它器官有间接影响
Oral health口腔健康 Betaine is shown to have a positive effect on moisturizing the tissue and cells lining the mouth (mucuous membrane)甜 菜碱显示可以有效润湿口腔内组织及细胞 Especially for people suffering from dry mouth problems特别是对于口干症患者 E.g. in products like lozenges, chewing gum, hard candy可应用于止咳糖，口香糖和硬糖。
Osmolyte H H C H 3 methyl groups
三个甲基
渗透压调节剂
H
H C N
+
H
C C
O
-
H
H C H H
H
O
Apply name/department/presentation title in 'header and footer'
5
Betaine: Two Key Biochemical Roles 甜菜碱在人体中的两个重要生化功能
Apply name/department/presentation title in 'header and footer' administration of labelled betaine
9
*Radioactivity (dpm/ g tissue) of broiler chick tissues 24 hours after oral
Apply name/department/presentation title in 'header and footer'
Apply name/department/presentation title in 'header and footer'
7
Why is Liver Health so Important? 为什么肝脏的健康很重要？
The largest gland in the body 人体最大腺体 The second largest organ in the body 人体第二大器官 Important to carbohydrate metabolism, lipid metabolism and protein metabolism 对糖代谢，蛋白质 的新陈代谢及脂肪代谢十分重要 The main site for transmethylation reactions 甲基化反应的主要场所 Liver cells are metabolically most active cells in the body 最活跃细胞 Excess ammonia in the blood causes fatigue 血中过高的氨会引起疲劳
Food 食品
Plant 植物
Cosmetics and Pharmaceuticals化妆品及药 Apply name/department/presentation title in 'header and footer' 品 （保健品）
4
The Structure of Betaine 甜菜碱的化学结构
2
What is Betafin® BF? 什么是天然甜菜碱？
Minimum 99% pure betaine anhydrous 最少99%无水纯 天然甜菜碱 Sometimes also called TMG (trimethylglycine) 也称三甲 基甘氨酸 Extracted from sugar beet molasses, 100 % natural product with no added chemicals 来自于甜菜糖蜜，是百 分百天然的产品 Naturally exists in all living material; both synthesized in the body and ingested in foods 天然存在于生物体，人体 可自身合成并可由食物摄入 Rich sources include spinach, wheat, seafood, beets 富含的食物包括菠菜、大麦、海产品、甜菜等
What is Fatty Liver? 什么是脂肪肝？
Fatty liver (steatosis) is the accumulation of extra fat in the liver cells 脂肪在肝脏的过度堆积
Fatty liver is normally diagnosed by liver function tests (ALT, AST, GGT) from blood samples and ultrasound or CT (computerized tomography) scan or MRI (magnetic resonance imaging)可通过血液化验、 超声、 CT、核磁共振诊断
Natural Betaine and Its Health Benefits
天然甜菜碱：
赋予产品更多健康概念的新功效成分
1
内容提要
天然甜菜碱及其主要生理功能及健康功效 甜菜碱在护肝、及体能表现方面的作用 应用天然甜菜碱的新品举例 总结
Apply name/department/presentation title in 'header and footer'
Betaine widely used for over 25 years in animal feeds and natural cosmetics products 甜菜碱应用于饲料及化 妆品已有超过25年的历史
Long historical use in Japan as a flavor compound in imitated seafood products 长久以来甜菜碱被用作模拟海 产品风味的香原料 Apply name/department/presentation title in 'header and footer'
Sugar
Chromatographic separation 色谱分离 (patented Danisco technology丹尼斯克专利)
Sugar 糖
Betaine 甜菜碱 Methyl donor, Osmoprotectant 甲基供体；渗透保护剂
Animal nutrition and health 动物营养与健康 Fermentation 发酵
GOOD LIVER HEALTH HAS A SIGNIFICANT EFFECT ON
OVERALL HEALTH AND WELLBEING 肝脏的健康对整个身体的健康和生存有很大的影响。
Apply name/department/presentation title in 'header and footer'
Apply name/department/presentation title in 'header and footer'
6
Health Benefits of Natural Betaine
天然甜菜碱的健康功能
Liver protection function 护肝功能
Homocysteine lowering降低同型半胱胺酸 Betaine is shown by several clinical trials to lower blood homocysteine levels一些临床试验显示甜菜碱能降低血中同型 半胱胺酸的水平 High homocysteine is widely considered as an independent risk factor for cardiovascular diseases高同型半胱胺酸被广 泛认为是一个导致心血管病的独立的危险因素 Betaine used often in combination with vitamins B6, B12 and folic acid甜菜碱经常与维生素B6、B12和叶酸辅配在一起 用。
The recent and growing incidence of fatty liver and associated liver diseases is mainly caused by today‟s lifestyle; Western diet, reduced exercise and alcohol consumption近期脂肪肝及肝脏疾病上升跟现在的生 活方式有关包括西方的膳食，运动的减少及饮酒 Longer term and larger fat accumulation may lead to liver inflammation (steatohepatitis) and further to serious liver diseases (fibrosis and cirrhosis) 长期及 大量的脂肪堆积会导致肝炎， 并会发展成更严重的肝 脏病变如纤维化及肝硬化。
8Байду номын сангаас
Fate of Dietary Betaine in the Body 甜菜碱在各器官的分布
Liver 肝脏 Kidney 肾脏 十二指肠 Colon 结肠 Plasma 血浆 肌肉 红血球 Fat 脂肪 0 2000 4000 6000 8000 10000
Radioactivity (dpm/g tissue)*
3
Betaine Production and Applications 天然甜菜碱的生产及应用
Sugar beet 甜菜 (0.2-0.3 % betaine)
Methyl donor
Bipolar electrolyte
Sugar beet plant Molasses 糖蜜 (3-6 % betaine) Pulp
Sports performance 运动表现 Betaine is shown in clinical trials to significantly improve strength and power during exercise临床验证表明甜菜碱能显著 提高运动中的力量表现。 Positive benefits for athletes and active people wanting to improve their performance对运动员们有正面的帮助，也能提 高普通人在运动中的表现
Imbalance in glycogen storage and depletion causes blood sugar level fluctuation 糖原的不平衡及过 度损耗将引起血糖波动
Risks associated with toxic build up 毒素堆积 Potential effects on skin and other organs 对皮肤和其它器官有间接影响
Oral health口腔健康 Betaine is shown to have a positive effect on moisturizing the tissue and cells lining the mouth (mucuous membrane)甜 菜碱显示可以有效润湿口腔内组织及细胞 Especially for people suffering from dry mouth problems特别是对于口干症患者 E.g. in products like lozenges, chewing gum, hard candy可应用于止咳糖，口香糖和硬糖。
Osmolyte H H C H 3 methyl groups
三个甲基
渗透压调节剂
H
H C N
+
H
C C
O
-
H
H C H H
H
O
Apply name/department/presentation title in 'header and footer'
5
Betaine: Two Key Biochemical Roles 甜菜碱在人体中的两个重要生化功能
Apply name/department/presentation title in 'header and footer' administration of labelled betaine
9
*Radioactivity (dpm/ g tissue) of broiler chick tissues 24 hours after oral
Apply name/department/presentation title in 'header and footer'
Apply name/department/presentation title in 'header and footer'
7
Why is Liver Health so Important? 为什么肝脏的健康很重要？
The largest gland in the body 人体最大腺体 The second largest organ in the body 人体第二大器官 Important to carbohydrate metabolism, lipid metabolism and protein metabolism 对糖代谢，蛋白质 的新陈代谢及脂肪代谢十分重要 The main site for transmethylation reactions 甲基化反应的主要场所 Liver cells are metabolically most active cells in the body 最活跃细胞 Excess ammonia in the blood causes fatigue 血中过高的氨会引起疲劳
Food 食品
Plant 植物
Cosmetics and Pharmaceuticals化妆品及药 Apply name/department/presentation title in 'header and footer' 品 （保健品）
4
The Structure of Betaine 甜菜碱的化学结构
2
What is Betafin® BF? 什么是天然甜菜碱？
Minimum 99% pure betaine anhydrous 最少99%无水纯 天然甜菜碱 Sometimes also called TMG (trimethylglycine) 也称三甲 基甘氨酸 Extracted from sugar beet molasses, 100 % natural product with no added chemicals 来自于甜菜糖蜜，是百 分百天然的产品 Naturally exists in all living material; both synthesized in the body and ingested in foods 天然存在于生物体，人体 可自身合成并可由食物摄入 Rich sources include spinach, wheat, seafood, beets 富含的食物包括菠菜、大麦、海产品、甜菜等
What is Fatty Liver? 什么是脂肪肝？
Fatty liver (steatosis) is the accumulation of extra fat in the liver cells 脂肪在肝脏的过度堆积
Fatty liver is normally diagnosed by liver function tests (ALT, AST, GGT) from blood samples and ultrasound or CT (computerized tomography) scan or MRI (magnetic resonance imaging)可通过血液化验、 超声、 CT、核磁共振诊断
Natural Betaine and Its Health Benefits
天然甜菜碱：
赋予产品更多健康概念的新功效成分
1
内容提要
天然甜菜碱及其主要生理功能及健康功效 甜菜碱在护肝、及体能表现方面的作用 应用天然甜菜碱的新品举例 总结
Apply name/department/presentation title in 'header and footer'
Betaine widely used for over 25 years in animal feeds and natural cosmetics products 甜菜碱应用于饲料及化 妆品已有超过25年的历史
Long historical use in Japan as a flavor compound in imitated seafood products 长久以来甜菜碱被用作模拟海 产品风味的香原料 Apply name/department/presentation title in 'header and footer'
Sugar
Chromatographic separation 色谱分离 (patented Danisco technology丹尼斯克专利)
Sugar 糖
Betaine 甜菜碱 Methyl donor, Osmoprotectant 甲基供体；渗透保护剂
Animal nutrition and health 动物营养与健康 Fermentation 发酵
GOOD LIVER HEALTH HAS A SIGNIFICANT EFFECT ON
OVERALL HEALTH AND WELLBEING 肝脏的健康对整个身体的健康和生存有很大的影响。
Apply name/department/presentation title in 'header and footer'
Apply name/department/presentation title in 'header and footer'
6
Health Benefits of Natural Betaine
天然甜菜碱的健康功能
Liver protection function 护肝功能
Homocysteine lowering降低同型半胱胺酸 Betaine is shown by several clinical trials to lower blood homocysteine levels一些临床试验显示甜菜碱能降低血中同型 半胱胺酸的水平 High homocysteine is widely considered as an independent risk factor for cardiovascular diseases高同型半胱胺酸被广 泛认为是一个导致心血管病的独立的危险因素 Betaine used often in combination with vitamins B6, B12 and folic acid甜菜碱经常与维生素B6、B12和叶酸辅配在一起 用。
The recent and growing incidence of fatty liver and associated liver diseases is mainly caused by today‟s lifestyle; Western diet, reduced exercise and alcohol consumption近期脂肪肝及肝脏疾病上升跟现在的生 活方式有关包括西方的膳食，运动的减少及饮酒 Longer term and larger fat accumulation may lead to liver inflammation (steatohepatitis) and further to serious liver diseases (fibrosis and cirrhosis) 长期及 大量的脂肪堆积会导致肝炎， 并会发展成更严重的肝 脏病变如纤维化及肝硬化。
8Байду номын сангаас
Fate of Dietary Betaine in the Body 甜菜碱在各器官的分布
Liver 肝脏 Kidney 肾脏 十二指肠 Colon 结肠 Plasma 血浆 肌肉 红血球 Fat 脂肪 0 2000 4000 6000 8000 10000
Radioactivity (dpm/g tissue)*