Plasma micro RNA for detection of early colorectal

专利名称：Plasma micro RNA for detection of early
colorectal cancer
发明人：ヒロネジャ，イ コス，マリトクセル,ロサノ サル
バテジャ，ファン，ホセ,カステイス，イ ガラン
ゴウ，アントニ,ヒラルデス，マリア，ドロレス
申请号：JP2014536355
申请日：20121020
公开号：JP2014530619A
公开日：
20141120
专利内容由知识产权出版社提供
专利附图：
摘要： The present invention generally relates to the field of colorectal cancer
detection and, more particularly, to a plasma micro RNA for detection of early colorectal cancer . In particular, the present invention encompasses a method for diagnosing or detecting colorectal neoplasms in a human subject , the kit and biomarkers . Methods of
diagnosing or detecting colorectal neoplasms in a human subject , the step that collecting one or more biological samples from a subject suspected to be suffering from colorectal neoplasms , one or more of the analyte one or more micro- RNA from whole expression patterns or step for measuring the level , and colorectal subject of the biological sample suspected of suffering from a neoplasm of the one or more micro-RNA from biological samples the method comprising the entire expression patterns , compared to one or more of the overall expression patterns of micro- RNA from normal subject biological sample , not the normal subject suffering from colorectal neoplasia a subject health , including the step of over-expression of the combination of miR19a and miR19b or miR19a and miR19b and miR15b, is indicative of colorectal cancer . [ Selection Figure ] Figure 1A
申请人：ホスピタル クリニク デ バルセロナ,セントロ デ インベスティガシオン バイオメディカ エン レド デ エンフェルメダデス ヘパティカス イ ディゲスティバス
地址：スペイン国 ０８０３６ バルセロナ， ビジャロエル， １７０,スペイン国， バルセロナ，コルセガ １８０
国籍：ES,ES
代理人：平木 祐輔,藤田 節,新井 栄一,田中 夏夫,菊田 尚子
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