BMS-833923_1059734-66-5_MSDS_MedChemExpress
聚丙烯酰胺MSDS报告
聚丙烯酰胺MSDS报告聚丙烯酰胺MSDS报告(化学品安全技术说明书)一、化学品化学品商品名:聚丙烯酰胺或PAM 英文名:Polyacrylamide (PAM)国家应急电话:120，119，110二、成分、组成信息化学品名称:聚丙烯酰胺相对分子量: 900万离子性:阳离子化学类别: 螯合剂型聚合物容积密度: 0.70gms/cm3 粘度:(1.0%SOL)950mPa?S 外观与性状: 白色粒状固体，稀释后呈无色液体,无臭水分(0.1%SOL):10%以下。
pH值:6.0--7.0三、危险性概述危险性类别:无侵入途径:无健康危害:无资料急性中毒:无慢性影响:未发现环境危害:无燃爆危险:本品易燃。
四、急救措施皮肤接触:脱去污染的衣着，用肥皂水和清水彻底冲洗皮肤。
眼睛接触:提起眼睑，用流动清水或生理盐水冲洗。
就医。
吸入:食入:通过动物实验证明此产品食入后不会中毒五、消防措施危险特性:用水灭火时，颗粒遇水后变滑，避免人员滑倒摔伤有害燃烧产物:无灭火方法:无火灾危险。
六、泄漏应急处理应急处理:颗粒遇水后变滑，避免人员滑倒摔伤七、操作处置与储存操作注意事项:无特别要求储存注意事项:储存于阴凉、通风的库房。
八、接触控制/个体防护个人注意事项:无特别要求工程控制:提供安全淋浴和洗眼设备。
眼睛防护:戴化学安全防护眼镜身体防护:无特别要求。
手防护:用大量水冲洗洗其它防护:九、理化特性颜色:白色粒状气味:无味第十部分稳定性和反应活性稳定性:稳定禁配物:产生放热反应的氧化物。
避免接触的条件: 聚合危害:不聚合分解产物:热的腐烂物可能产生，氢化合物气体，氮氧化物，碳氧化合物等。
第十一部分毒理学资料急性毒性:无毒性刺激性:第十二部分生态学资料生态毒性:无生物降解性: 非生物降解性: 其它有害作用:第十三部分废弃处置废弃物性质: 废弃处置方法:在不违反传统处理规则的前提下，用水冲洗包装物，然后用此水来溶解产品进行使用。
废弃注意事项:第十四部分运输信息危险货物编号:不适用包装标志: 包装类别: 包装方法:编织袋包装或桶包装，每包或桶为25公斤。
《中国药典》(2020年版)复方磺胺恶唑片中的甲氧苄啶含量测
《中国药典》(2020年版)复方磺胺噁唑片中的甲氧苄啶含量测甲氧苄啶（Trimethoprim, TMP），又称为甲氧苄氨嘧啶、甲氧苄嘧啶，是一种抗菌增效药，与磺胺类药物联合使用时，能使磺胺类药物抗菌谱扩大、抗菌活性大大增强。
由于其独特的作用，甲氧苄啶在养殖业病害防治中被广泛应用。
迪信泰检测平台采用高效液相色谱(HPLC)和液相色谱-三重四极杆质谱(LC-MS/MS)法，可高效、精准的检测甲氧苄啶的含量变化。
此外，我们还提供其他抗生素检测服务，以满足您的不同需求。
HPLC和LC-MS测定甲氧苄啶样本要求：1. 请确保样本量大于0.2g或者0.2mL。
周期：2~3周项目结束后迪信泰检测平台将会提供详细中英文双语技术报告，报告包括：1. 实验步骤（中英文）2. 相关质谱参数（中英文）3. 质谱图片4. 原始数据5. 甲氧苄啶含量信息应用范围：本方法采用高效液相色谱法测定复方磺胺甲恶唑片中磺胺甲恶唑和甲氧苄啶的含量。
本方法适用于复方磺胺甲恶唑片。
方法原理：供试品加甲醇稀释，最终用流动相定量稀释后，进入高效液相色谱仪进行色谱分离，用紫外吸收检测器，于波长240nm处检测磺胺甲恶唑和甲氧苄啶的吸收值，计算出其含量。
试剂： 1. 0.1mol/L盐酸2. 乙腈3. 三乙胺4. 氢氧化钠试液5. 冰醋酸仪器设备： 1. 仪器1.1 高效液相色谱仪1.2 色谱柱十八烷基硅烷键合硅胶为填充剂，理论塔板数按磺胺甲恶唑峰计算不低于4000。
磺胺甲恶唑和甲氧苄啶的分离度应符合要求。
1.3 紫外吸收检测器2. 色谱条件2.1 流动相：水乙腈三乙胺=799 200 1（用氢氧化钠试液或冰醋酸调节pH 值至5.9。
）2.2 检测波长：240nm2.3 柱温：室温试样制备：1. 称取供试品取本品10片，精密称定，研细，精密称取适量（约相当于磺胺甲恶唑44mg）置100mL量瓶中。
2. 对照品溶液的制备精密称取磺胺甲恶唑对照品和甲氧苄啶对照品适量，用0.1mol/L盐酸溶液溶解并定量稀释制成每1mL中约含有磺胺甲恶唑0.44mg的和甲氧苄啶89µg的溶液。
CAS号413611-93-5_10074-G5_MedBio_物理性质
1、产品物理参数：
常用名
10074-G5
英文名
10074-G5
CAS号
413611-93-5
分子量
332.313
密度
1.4±0.1 g/cm3
沸点
538.6±60.0 °C at 760 mmHg
分子式
C18H12N4O3
熔点
无资料
闪点
279.5±32.9 °C
2、技术资料：
体外研究
10074-G5抑制Daudi Burkitt淋巴瘤细胞的生长并破坏c-Myc / Max二聚化。针对Daudi和HL-60细胞的IC50值分别为15.6和13.5μM[1]。10074-G5在区域Arg363-Ile381中结合Myc肽Myc353-437，Kd值为2.8μM。10074-G5结合在由诱导螺旋结构域（Leu370-Arg378）的N末端的扭结（Asp379-Ile381）产生的空腔中[3]。
≥98%
品牌
货号
中文名称
英文名称
CAS
包装
纯度
MedBio
MED11457
CDK inhibitor II
CDK inhibitor II
1269815-17-9
50mg
≥98%
品牌
货号
中文名称
英文名称
CAS
包装
纯度
MedBio
MED11591
(S)-CCG-1423
(S)-CCG-1423
None
体内研究
静脉注射20 mg / kg小鼠的血浆半衰期为10074-G5，为37分钟，血药浓度峰值为58μM，比肿瘤峰值浓度高10倍[1]。
3、同类产品列表：
四种烷基咪唑磷酸酯离子液体的热力学性质
化工进展Chemical Industry and Engineering Progress2024 年第 43 卷第 3 期四种烷基咪唑磷酸酯离子液体的热力学性质刘泽鹏，曾纪珺，唐晓博，赵波，韩升，廖袁淏，张伟（西安近代化学研究所氟氮化工资源高效开发与利用国家重点实验室，陕西 西安 710065）摘要：针对烷基咪唑磷酸酯离子液体的热物性数据较少的问题，本文在常压下测定了1-乙基-3-甲基咪唑磷酸二氢盐（[EMIM][DHP]）、1-乙基-3-甲基咪唑磷酸二甲酯盐（[EMIM][DMP]）、1-乙基-3-甲基咪唑磷酸二乙酯盐（[EMIM][DEP]）、1-丁基-3-甲基咪唑磷酸二丁酯盐（[BMIM][DBP]）四种烷基咪唑磷酸酯离子液体的密度、黏度（293.15~353.15K ）和电导率（293.15~343.15K ），并且测定了四种离子液体的热稳定性。
结果表明，离子液体的密度、黏度随温度的升高而减小，而电导率随温度的升高而增大。
采用自然对数方程关联四种离子液体的密度，根据实验值计算到了离子液体体积性质；采用VFT 方程关联离子液体黏度和电导率，其中密度与电导率的实验值与模型相关系数R 2达到0.9999，黏度相关系数R 2达到0.99999，实验测定的数据与模型一致；四种离子液体的热稳定性相近，分解温度均在271.9~278.6℃范围内；瓦尔登规则分析表明，四种烷基咪唑磷酸酯离子液体符合Walden 规则，而[EMIM][DMP]和[EMIM][DEP]被归类为“good ionic liquids ”。
关键词：烷基咪唑磷酸酯离子液体；密度；黏度；电导率；热稳定性中图分类号：TQ013.1 文献标志码：A 文章编号：1000-6613（2024）03-1484-08Thermodynamic properties of four alkyl imidazolium phosphate ionicliquidsLIU Zepeng ，ZENG Jijun ，TANG Xiaobo ，ZHAO Bo ，HAN Sheng ，LIAO Yuanhao ，ZHANG Wei(State Key Laboratory of Fluorine & Nitrogen Chemicals, Xi ’an Modern Chemistry Research Institute, Xi ’an 710065,Shaanxi, China)Abstract: The density, viscosity, and conductivity of 1-ethyl-3-methylimidazolium dihydrogen-phosphate ([EMIM][DHP]), 1-ethyl-3-methylimidazolium dimethylphosphate ([EMIM][DMP]), 1-ethyl-3-methylimidazolium diethylphosphate ([EMIM][DEP]) and 1-butyl-3-methylimidazolium dibutyl-phosphate ([BMIM][DBP]) ionic liquids were measured in the temperature range of 293.15K to 353.15K under ambient conditions. Some important volumetric properties, including the isobaric thermal expansion coefficients, molecular volume, standard entropy and lattice potential energy were calculated from the experimental density values. The thermal gravimetric analysis was performed in the temperature range of 35℃ to 700℃, resulting in thermal decomposition temperatures up to 271.9—278.6℃. The Walden rule analysis demonstrated that four phosphate ionic liquids complied with the Walden rule well, while [EMIM][DMP] and [EMIM][DEP] were classified as “good ionic liquids ”.Keywords: alkyl imidazolium phosphate ionic liquids; density; viscosity; conductivity; thermal stability研究开发DOI ：10.16085/j.issn.1000-6613.2023-1722收稿日期：2023-09-28；修改稿日期：2023-12-05。
重组贻贝粘蛋白的表征及功效评价
生物技术进展 2023 年 第 13 卷 第 4 期 596 ~ 603Current Biotechnology ISSN 2095‑2341研究论文Articles重组贻贝粘蛋白的表征及功效评价李敏 ， 魏文培 ， 乔莎 ， 郝东 ， 周浩 ， 赵硕文 ， 张立峰 ， 侯增淼 *西安德诺海思医疗科技有限公司，西安 710000摘要：为了推进重组贻贝粘蛋白在医疗、化妆品领域的应用，对大肠杆菌规模化发酵及纯化生产获得的重组贻贝粘蛋白进行了表征及功效评价。
经Edman 降解法、基质辅助激光解吸电离飞行时间质谱、PITC 法、非还原型SDS -聚丙烯酰胺凝胶电泳法、凝胶法、改良的Arnow 法对重组贻贝粘蛋白进行氨基酸N 端测序、相对分子量分析、氨基酸组成分析、蛋白纯度分析、内毒素含量测定、多巴含量测定；通过细胞迁移、斑马鱼尾鳍修复效果对重组贻贝粘蛋白进行功效评价。
结果显示，获得的重组贻贝粘蛋白与理论的一级结构一致，蛋白纯度达95%以上，内毒素<10 EU ·mg -1,多巴含量大于5%；重组贻贝粘蛋白浓度为60 μg ·mL -1时能够显著促进细胞增殖的活性（P <0.01）；斑马鱼尾鳍面积样品组与模型对照组相比极显著增加（P <0.001）。
研究结果表明，重组贻贝粘蛋白具有显著的促细胞迁移和修复愈合的功效，具备作为生物医学材料的潜质。
关键词：贻贝粘蛋白；基因重组；生物材料；表征；功效评价DOI ：10.19586/j.20952341.2023.0021 中图分类号：S985.3+1 文献标志码：ACharacterization and Efficacy Evaluation of Recombinant Mussel Adhesive ProteinLI Min ， WEI Wenpei ， QIAO Sha ， HAO Dong ， ZHOU Hao ， ZHAO Shuowen ， ZHANG Lifeng ，HOU Zengmiao *Xi'an DeNovo Hith Medical Technology Co.， Ltd ， Xi'an 710000， ChinaAbstract ：In order to promote the application of recombinant mussel adhesive protein in the medical and cosmetics field ， the recombi⁃nant mussel adhesive protein obtained from scale fermentation and purification of Escherichia coli was characterized and its efficacy was evaluated. Amino acid N -terminal sequencing ， relative molecular weight analysis ， amino acid composition analysis ， protein purityanalysis ， endotoxin content ， dihydroxyphenylalanine （DOPA ） content of recombinant mussel adhesive protein were determined by the following methods ： Edman degradation ， matrix -assisted laser desorption ionization time -of -flight mass spectrometry （MALDI -TOF -MS ）， phenyl -isothiocyanate （PITC ）， nonreductive SDS -polyacrylamide gel electrophoresis （SDS -PAGE ）， gel method ， modified Ar⁃now. The efficacy of recombinant mussel adhesive protein was evaluated by cell migration and repairing effect of zebrafish tail fin. Re⁃sults showed that the obtained recombinant mussel adhesive protein was confirmed to be consistent with the theoretical primary structure ， protein purity of more than 95%， endotoxin <10 EU ·mg -1， DOPA content above 5%. When the recombinant mussel adhesive protein concentration was 60 μg ·mL -1， the effect of promoting cell proliferation was the most obvious ， and it had very significant activity （P <0.01）. The caudal fin area of zebrafish in sample group was significantly increased compared with model control group （P <0.001）. The results indicated that recombinant mussel adhesive protein can promote cell migration and repair healing and has the potential to be used as biomedical materials.Key words ：mussel adhesive protein ； gene recombination ； biological materials ； representation ； efficacy evaluation贻贝粘蛋白（mussel adhesive protein ， MAP ）也称作贻贝足丝蛋白（mussel foot protein ，Mfps ），收稿日期：2023⁃02⁃24； 接受日期：2023⁃03⁃31联系方式：李敏 E -mail:*******************;*通信作者 侯增淼 E -mail:***********************.cn李敏，等：重组贻贝粘蛋白的表征及功效评价是海洋贝类——紫贻贝（Mytilus galloprovincalis）、厚壳贻贝（Mytilus coruscus）、翡翠贻贝（Perna viri⁃dis）等分泌的一种特殊的蛋白质，贻贝中含有多种贻贝粘蛋白，包括贻贝粘蛋白（Mfp 1～6）、前胶原蛋白（precollagens）和基质蛋白（matrix proteins）等［1］。
LORD Corporation 产品说明书 - CHEMLOK 8560S-1
USA SAFETY DATA SHEET1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATIONProduct name: CHEMLOK 8560S-1Product Use/Class: Aqueous AdhesiveLORD Corporation111 LORD DriveCary, NC 27511-7923 USATelephone: 814 868-3180Non-Transportation Emergency: 814 763-2345 Chemtrec 24 Hr Transportation Emergency No.800 424-9300 (Outside Continental U.S. 703 527-3887)EFFECTIVE DATE: 12/20/20212. HAZARDS IDENTIFICATIONGHS CLASSIFICATION:Serious eye damage/eye irritation Category 2B Skin sensitization Category 1A Carcinogenicity Category 2Specific target organ systemic toxicity (single exposure) Category 2 blood system Specific target organ systemic toxicity (repeated exposure) Category 2 blood system Hazardous to the aquatic environment - acute hazard Category 2 Hazardous to the aquatic environment - chronic hazard Category 2GHS LABEL ELEMENTS:Symbol(s)Signal WordW ARNINGHazard StatementsCauses eye irritation.May cause an allergic skin reaction. Suspected of causing cancer.May cause damage to organs.(blood system)May cause damage to organs through prolonged or repeated exposure.(blood system) Toxic to aquatic life.Toxic to aquatic life with long lasting effects.Precautionary Statements PreventionObtain special instructions before use.Do not handle until all safety precautions have been read and understood. Wear protective gloves.Use personal protective equipment as required. Do not breathe dust/fume/gas/mist/vapors/spray. Wash thoroughly after handling.Do not eat, drink or smoke when using this product.Contaminated work clothing should not be allowed out of the workplace. Avoid release to the environment.Product: CHEMLOK 8560S-1, Effective Date: 12/20/2021ResponseGet medical advice/attention if you feel unwell.Call a POISON CENTER or doctor/physician if exposed or you feel unwell.Specific treatment (see supplemental first aid instructions on this label).IF ON SKIN: Wash with plenty of soap and water.If skin irritation or rash occurs: Get medical advice/attention.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.Continue rinsing.If eye irritation persists: Get medical advice/attention.Wash contaminated clothing before reuse.Collect spillage.StorageStore locked up.Disposal:Dispose of contents/container in accordance with waste/disposal laws and regulations of your country or particular locality.Other Hazards:This product contains component(s) which have the following warnings; however based on the GHS classification criteria of your country or locale, the product mixture may be outside the respective category(s).Acute: May cause mild skin irritation. In elevated-temperature applications, product may release vapors that may produce cyanosis in the absence of sufficient ventilation or adequate respiratory protection. 4,4'-Diphenylmethane bis-maleimide is harmful by inhalation. Avoid breathing sanding dust from this product. May be harmful ifswallowed. Ingestion is not an expected route of entry in industrial or commercial uses.Chronic: Prolonged or repeated contact may result in dermatitis. The nitrogen substituted aromatic in this product gave positive results for mutagenicity in an Ames Assay study while two other mutagenicity studies proved negative.IARC has designated carbon black as Group 2B - inadequate evidence for carcinogenicity in humans, but sufficient evidence in experimental animals. In 2006 IARC reaffirmed its 1995 finding that there is "inadequate evidence"from human health studies to assess whether carbon black causes cancer in humans. Further, epidemiologicalevidence from well-conducted investigations has shown no causative link between carbon black exposure and the risk of malignant or non-malignant respiratory disease in humans. IARC has identified the proprietary curative in this product as an "animal suspected" carcinogen, Group 3, which downgrades a previous NCI report of it as an "animal positive" carcinogen.3. COMPOSITION/INFORMATION ON INGREDIENTSChemical Name CAS Number RangeNitrogen substituted aromatic PROPRIETARY15 - 20%Zinc compound PROPRIETARY 5 - 10%4,4'-Diphenylmethane bis-maleimide13676-54-5 1 - 5%Carbon black1333-86-4 1 - 5%Nonylphenol ethoxylate compound PROPRIETARY0.9 - 1%Curative PROPRIETARY0.1 - 0.9%Any "PROPRIETARY" component(s) in the above table is considered trade secret, thus the specific chemical and its exact concentration is being withheld.4. FIRST AID MEASURESFIRST AID - EYE CONTACT: Flush eyes immediately with large amount of water for at least 15 minutes holding eyelids open while flushing. Get prompt medical attention.FIRST AID - SKIN CONTACT: Flush contaminated skin with large amounts of water while removing contaminated clothing. Wash affected skin areas with soap and water. Get medical attention if symptoms occur.FIRST AID - INHALATION: Move person to fresh air. Restore and support continued breathing. If breathing is difficult, give oxygen. Get immediate medical attention.Product: CHEMLOK 8560S-1, Effective Date: 12/20/2021FIRST AID - INGESTION: If swallowed, do not induce vomiting. Call a physician or poison control center immediately for further instructions. Never give anything by mouth if victim is rapidly losing consciousness, unconscious or convulsing.5. FIRE-FIGHTING MEASURESSUITABLE EXTINGUISHING MEDIA: Carbon Dioxide, Dry Chemical, Foam, Water FogUNSUITABLE EXTINGUISHING MEDIA: Not determined for this product.SPECIFIC HAZARDS POSSIBLY ARISING FROM THE CHEMICAL: Keep containers tightly closed. Closed containers may rupture when exposed to extreme heat. Use water spray to keep fire exposed containers cool. WARNING: Due to the combustible nature of the dried film of this product and the potential for smoldering or fire, the accumulation and buildup of the dried film on spray booth walls and floors, spindles, fixtures and other surfaces should be avoided, and any buildup should be removed. Keep the dried film accumulations away from sparks, friction, impact, high heat (>235 F/>112 C) or other sources of ignition. These conditions could cause the dried film to ignite very readily and quickly, and the resulting smoldering or fire may be difficult to extinguish. During removal of accumulation/buildup of this product, take precautions to avoid heat, friction and impact during the cleaning process. Use paint stripper, brass brush, or plastic scraper for cleaning. In the event of smoldering or a fire involving the dried product, Cold Fire®** fire suppressing agent is preferred as the extinguishing medium. If Cold Fire® is not available, use water spray as the extinguishing medium. Take efforts to ensure that these agents reach the base of the smoldering or fire. Parker-LORD Corporation will not be responsible for personal injuries, property damage or any other damages arising from the accumulation (buildup, cleaning/removal or any related smoldering or fire) resulting from the use of this product. Refer to the Chemlok® Safe Handling Guide for additional information. **NOTE: Parker-LORD Corporation has determined Cold Fire® fire suppressing agent to be effective in extinguishing fires involving dried Chemlok® adhesives. Parker-LORD does not recommend any particular equipment or system for use in delivering or applying Cold Fire® products. Customer is responsible for determining that Cold Fire® products and any delivery equipment or system is appropriate and effective for customer's specific needs. During a fire, irritating and/or toxic gases and particulate may be generated by thermal decomposition or combustion. SPECIAL PROTECTIVE EQUIPMENT AND PRECAUTIONS FOR FIRE-FIGHTERS: Wear full firefighting protective clothing, including self-contained breathing apparatus (SCBA). If water is used, fog nozzles are preferable.6. ACCIDENTAL RELEASE MEASURESPERSONAL PRECAUTIONS, PROTECTIVE EQUIPMENT AND EMERGENCY PROCEDURES: Avoid breathing vapors. Avoid contact. Use appropriate respiratory protection for large spills or spills in confined area. See Section 5 for cautionary information on the dried residue of this product.ENVIRONMENTAL PRECAUTIONS: Do not contaminate bodies of water, waterways, or ditches, with chemical or used container.METHODS AND MATERIALS FOR CONTAINMENT AND CLEANUP: Notify appropriate authorities if necessary. Contain and remove with inert absorbent material. Avoid contact. Keep non-essential personnel away from spill area. Before attempting cleanup, refer to hazard caution information in other sections of this Safety Data Sheet.7. HANDLING AND STORAGEHANDLING: Keep closure tight and container upright to prevent leakage. Avoid skin and eye contact. Wash thoroughly after handling. Do not handle until all safety precautions have been read and understood. Empty containers should not be re-used. Use with adequate ventilation. See Section 5 for cautionary information on handling of the dried residue of this product. Avoid breathing sanding dust from this product.STORAGE: Store only in well-ventilated areas. Keep from freezing. Keep container closed when not in use. INCOMPATIBILITY: Strong acids, bases, and strong oxidizers.8. EXPOSURE CONTROLS/PERSONAL PROTECTIONCOMPONENT EXPOSURE LIMIT Chemical Name ACGIH TLV-TWA ACGIH TLV-STELOSHA PEL-TWAOSHA PEL-CEILINGSkinProduct: CHEMLOK 8560S-1, Effective Date: 12/20/2021Nitrogen substituted aromatic N.E.N.E.N.E. N.E. N.A. Zinc compound2 mg/m3 10 mg/m3 5 mg/m3 N.E. N.A. 4,4'-Diphenylmethane bis-maleimide N.E. N.E. N.E. N.E. N.A. Carbon black3 mg/m3 N.E. 3.5 mg/m3 N.E. N.A. Nonylphenol ethoxylate compound N.E. N.E. N.E. N.E. N.A. CurativeN.E.N.E.N.E.N.E.N.A.N.A. - Not Applicable, N.E. - Not Established, S - Skin DesignationEngineering controls: Sufficient ventilation in pattern and volume should be provided in order to maintain air contaminant levels below recommended exposure limits.PERSONAL PROTECTION MEASURES/EQUIPMENT:RESPIRATORY PROTECTION: Use a NIOSH approved chemical/mechanical filter respirator designed to remove a combination of particulates and organic vapor if occupational limits are exceeded. For emergencysituations, confined space use, or other conditions where exposure limits may be greatly exceeded, use an approved air-supplied respirator. For respirator use observe OSHA regulations (29CFR 1910.134) or use in accordance with applicable laws and regulations of your country or particular locality.SKIN PROTECTION: Use neoprene, nitrile, or rubber gloves to prevent skin contact.EYE PROTECTION: Use safety eyewear including safety glasses with side shields and chemical goggles where splashing may occur.OTHER PROTECTIVE EQUIPMENT: Remove and wash contaminated clothing before reuse.HYGIENIC PRACTICES: Wash hands before eating, smoking, or using toilet facility. Do not smoke in any chemical handling or storage area. Food or beverages should not be consumed anywhere this product is handled or stored. Wash thoroughly after handling.9. PHYSICAL AND CHEMICAL PROPERTIESTypical values, not to be used for specification purposes.ODOR:Odorless VAPOR PRESSURE:N.D.APPEARANCE: Green/BlackVAPOR DENSITY:Heavier than Air PHYSICAL STATE:Thixotropic liquid LOWER EXPLOSIVE LIMIT: Not Applicable FLASH POINT: ≥ 201 °F, 93 °C Setaflash Closed Cup UPPER EXPLOSIVE LIMIT:Not Applicable BOILING RANGE:100 °CEVAPORATION RATE: Slower than n-butyl-acetateAUTOIGNITION TEMPERATURE: N.D. DENSITY:1.2 g/cm3 (10.00 lb/gal) DECOMPOSITION TEMPERATURE:N.D. VISCOSITY, DYNAMIC: ≥50 mPa.s @ 25 °C ODOR THRESHOLD: N.D.VISCOSITY, KINEMATIC: ≥42 mm2/s @ 25 °C SOLUBILITY IN H2O:Water Dispersible VOLATILE BY WEIGHT: 56.93 % pH:6.0 VOLATILE BY VOLUME:66.72 % FREEZE POINT:N.D. VOC CALCULATED: 0.02 lb/gal , 3 g/l COEFFICIENT OF WATER/OILDISTRIBUTION:N.D.LEGEND: N.A. - Not Applicable, N.E. - Not Established, N.D. - Not Determined10. STABILITY AND REACTIVITYHAZARDOUS POLYMERIZATION: Hazardous polymerization will not occur under normal conditions.STABILITY: Product is stable under normal storage conditions.Product: CHEMLOK 8560S-1, Effective Date: 12/20/2021CONDITIONS TO AVOID: High temperatures.; For dried product issues, refer to Section 5 of the (M)SDS.; DO NOT ALLOW THIS MATERIAL TO DRY OUT. As a solid, p-benzoquinone dioxime is flammable, and it may explode if exposed to shock, friction or heat.INCOMPATIBILITY: Strong acids, bases, and strong oxidizers.HAZARDOUS DECOMPOSITION PRODUCTS: Decomposition due to high temperatures or a fire causes the formation of irritating and/or toxic gases, organic vapors or fumes., May contain CO, CO2, oxides of nitrogen, oxides of sulfur, halogenated by-products, Carbon dioxide, carbon monoxide, chlorine, hydrogen chloride, Phosgene, Metal oxides11. TOXICOLOGICAL INFORMATIONEXPOSURE PATH: Refer to section 2 of this SDS.SYMPTOMS: Refer to section 2 of this SDS.TOXICITY MEASURES:Chemical NameLD50/LC50 Nitrogen substituted aromatic Oral LD50: rat 1,100 mg/kgZinc compoundOral LD50: Rat > 5,000 mg/kg Dermal LD50: Rat > 2,000 mg/kgGHS LC50 (vapour): Acute toxicity point estimate 55 mg/l Inhalation LC50: Rat > 5,700 mg/m3 /4 h 4,4'-Diphenylmethane bis-maleimide Oral LD50: Rat > 5 g/kgDermal LD50: rat > 5,400 mg/kgGHS LC50 (dust and mist): rat 0.52 mg/l Inhalation ATE: 11 mg/l Carbon blackOral LD50: Rat > 15,400 mg/kg Dermal LD50: Rabbit > 3 g/kgGHS LC50 (vapour): Acute toxicity point estimate 55 mg/l : Nonylphenol ethoxylate compound N.D.CurativeOral LD50: Rat 464 mg/kgGHS LC50 (vapour): Acute toxicity point estimate 55 mg/l Inhalation LC50: Rat > 5 mg/l /4 hGerm cell mutagenicity: No classification proposedCarcinogenicity: Category 2 - Suspected of causing cancer. Components contributing to classification: Curative.Reproductive toxicity: No classification proposed12. ECOLOGICAL INFORMATIONECOTOXICITY:Chemical NameEcotoxicityNitrogen substituted aromatic N.D. Zinc compoundN.D.4,4'-Diphenylmethane bis-maleimide Fish: Oncorhynchus mykiss (rainbow trout) > 0.145 mg/l96 hCarbon blackN.D. Nonylphenol ethoxylate compound N.D.CurativeFish: Danio rerio (zebra fish) 24 mg/l96 h Static Invertebrates: Daphnia magna (Water flea) 3.5 mg/l48 h StaticPERSISTENCE AND DEGRADABILITY: Not determined for this product.BIOACCUMULATIVE: Not determined for this product.MOBILITY IN SOIL: Not determined for this product.OTHER ADVERSE EFFECTS: Not determined for this product.13. DISPOSAL CONSIDERATIONSDISPOSAL METHOD: Disposal should be done in accordance with Federal (40CFR Part 261), state and local environmental control regulations. If waste is determined to be hazardous, use licensed hazardous waste transporter and disposal facility. Waste streams, including the dried adhesive residue, resulting from the use of this product should be tested for RCRA characteristics, including ignitability, to determine any applicable waste classifications.14. TRANSPORT INFORMATIONUS DOT RoadProper Shipping Name: Environmentally hazardous substances, liquid, n.o.s.Hazard Class: 9SECONDARY HAZARD: NoneUN/NA Number: 3082Packing Group: IIIEmergency Response Guide Number: 171For US DOT non-bulk road shipments this material may be classified as NOT REGULATED. For the mostaccurate shipping information, refer to your transportation/compliance department regarding changes inpackage size, mode of shipment or other regulatory descriptors.IATA CargoPROPER SHIPPING NAME: Environmentally hazardous substance, liquid, n.o.s.Hazard Class: 9HAZARD CLASS: NoneUN NUMBER: 3082PACKING GROUP: IIIEMS: 9LIMDGPROPER SHIPPING NAME: Environmentally hazardous substance, liquid, n.o.s.Hazard Class: 9HAZARD CLASS: NoneUN NUMBER: 3082PACKING GROUP: IIIEMS: F-AThe listed transportation classification applies to non-bulk shipments. It does not address regulatory variations due to changes in package size, mode of shipment or other regulatory descriptors. For the most accurate shipping information, refer to your transportation/compliance department.15. REGULATORY INFORMATIONU.S. FEDERAL REGULATIONS: AS FOLLOWS:SARA SECTION 313This product contains the following substances subject to the reporting requirements of Section 313 of Title III of the Superfund Amendment and Reauthorization Act of 1986 and 40 CFR part 372.:Chemical Name CAS Number Weight % Less ThanZinc compound PROPRIETARY10.0%TOXIC SUBSTANCES CONTROL ACT:INVENTORY STATUSThe chemical substances in this product are on the active TSCA Section 8 Inventory or exempt.EXPORT NOTIFICATIONThis product contains the following chemical substances subject to the reporting requirements of TSCA 12(B) if exported from the United States:None16. OTHER INFORMATIONUnder HazCom 2012 it is optional to continue using the HMIS rating system. It is important to ensure employees have been trained to recognize the different numeric ratings associated with the HazCom 2012 and HMIS schemes.HMIS RATINGS - HEALTH: 2* FLAMMABILITY: 1 PHYSICAL HAZARD: 0* - Indicates a chronic hazard; see Section 2Revision: New GHS SDS FormatEffective Date: 12/20/2021DISCLAIMERThe information contained herein is, to the best of our knowledge and belief, accurate. However, since the conditions of handling and use are beyond our control, we make no guarantee of results, and assume no liability for damages incurred by use of this material. It is the responsibility of the user to comply with all applicable federal, state and local laws and regulations.。
4-乙氧基苯甲酸甲酯核磁共振氢谱
乙氧基苯甲酸甲酯是一种常见的有机化合物，其核磁共振氢谱是研究该化合物结构和性质的重要手段。
本文将针对乙氧基苯甲酸甲酯的核磁共振氢谱进行详细的解析和分析，以期为读者提供深入了解该化合物的参考。
1. 乙氧基苯甲酸甲酯的结构乙氧基苯甲酸甲酯的分子式为C9H10O3，结构式为CH3O2CC6H4OCH3。
该化合物是一种苯甲酸甲酯衍生物，具有独特的结构特征，其中乙氧基和苯环上的甲基是该化合物的两个重要官能团。
2. 乙氧基苯甲酸甲酯的核磁共振氢谱乙氧基苯甲酸甲酯的核磁共振氢谱可以通过核磁共振技术获取，提供了该化合物中氢原子的化学环境和化学位移信息。
在核磁共振氢谱图上，乙氧基苯甲酸甲酯的氢原子信号将呈现出多个峰和峰积分面积，通过对这些峰和面积的解析可以获得该化合物的结构信息。
3. 核磁共振氢谱图解析在乙氧基苯甲酸甲酯的核磁共振氢谱图上，可能会观察到以下几个峰和峰积分面积：- 低场区域出现的峰：1.2-1.5 ppm，代表乙氧基和苯环上的甲基所对应的氢原子。
- 中场区域出现的峰：2.3-2.6 ppm，代表分子中其它未取代的甲烷氢原子。
- 高场区域出现的峰：7.0-8.0 ppm，代表苯环上不同位置的氢原子。
4. 核磁共振氢谱解析结果通过对乙氧基苯甲酸甲酯的核磁共振氢谱图进行解析，可以得到以下结论：- 乙氧基和苯环上的甲基所对应的氢原子呈现出不同的化学环境和化学位移；- 分子中其它未取代的甲烷氢原子的化学位移较为集中；- 苯环上不同位置的氢原子呈现出明显的化学位移差异。
5. 乙氧基苯甲酸甲酯的结构特征通过核磁共振氢谱的解析，可以得知乙氧基苯甲酸甲酯分子中各个部分的化学环境和化学位移差异，进而推断出该化合物的结构特征。
乙氧基苯甲酸甲酯分子中的乙氧基和苯环上的甲基是该化合物的重要结构特征，其化学位移差异为进一步研究该化合物提供了重要信息。
6. 结论乙氧基苯甲酸甲酯的核磁共振氢谱是其结构和性质研究的重要手段，通过对其氢原子的化学环境和化学位移信息进行解析，可以获取该化合物的结构特征。
BMS-986205-SDS-MedChemExpress
Inhibitors, Agonists, Screening LibrariesSafety Data Sheet Revision Date:Oct.-10-2018Print Date:Oct.-10-20181. PRODUCT AND COMPANY IDENTIFICATION1.1 Product identifierProduct name :BMS-986205Catalog No. :HY-101560CAS No. :1923833-60-61.2 Relevant identified uses of the substance or mixture and uses advised againstIdentified uses :Laboratory chemicals, manufacture of substances.1.3 Details of the supplier of the safety data sheetCompany:MedChemExpress USATel:609-228-6898Fax:609-228-5909E-mail:sales@1.4 Emergency telephone numberEmergency Phone #:609-228-68982. HAZARDS IDENTIFICATION2.1 Classification of the substance or mixtureGHS Classification in accordance with 29 CFR 1910 (OSHA HCS)Skin irritation (Category 2), H315Serious eye damage (Category 1), H318Respiratory sensitisation (Category 1), H334Skin sensitisation (Category 1), H317Germ cell mutagenicity (Category 2), H341Reproductive toxicity (Category 2), H361Specific target organ toxicity - single exposure (Category 1), H370Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335Chronic aquatic toxicity (Category 4), H4132.2 GHS Label elements, including precautionary statementsPictogramSignal word DangerHazard statement(s)H315: Causes skin irritation.H317: May cause an allergic skin reactionH318: Causes serious eye damage.H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.H335: May cause respiratory irritation.H341: Suspected of causing genetic defects.H361: Suspected of damaging fertility or the unborn child.H370: Causes damage to organs.H413: May cause long lasting harmful effects to aquatic life.Precautionary statement(s)P201: Obtain special instructions before use.P202: Do not handle until all safety precautions have been read and understood.P260: Do not breathe dust ⁄ fume ⁄ gas ⁄ mist ⁄ vapors ⁄ spray.P264: Wash skin thoroughly after handling.P270: Do not eat, drink or smoke when using this product.P271: Use only outdoors or in a well-ventilated area.P272: Contaminated work clothing should not be allowed out of the workplace.P273: Avoid release to the environment.P280: Wear protective gloves ⁄ eye protection ⁄ face protection.P302 + P352: IF ON SKIN: Wash with plenty of soap and water.P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.Continue rinsing.P310: Immediately call a POISON CENTER ⁄doctor.P321: Specific treatment (see supplemental first aid instructions on this label).P333 + P313: If skin irritation or rash occurs: Get medical advice ⁄ attention.P362: Take off contaminated clothing and wash before reuse.P403 + P233: Store in a well-ventilated place. Keep container tightly closed.P405: Store locked up.P501: Dispose of contents ⁄ container to an approved waste disposal plant.2.3 Other hazardsNone.3. COMPOSITION/INFORMATION ON INGREDIENTS3.1 SubstancesSynonyms:NoneFormula:C24H24ClFN2OMolecular Weight:410.91CAS No. :1923833-60-64. FIRST AID MEASURES4.1 Description of first aid measuresEye contactRemove any contact lenses, locate eye-wash station, and flush eyes immediately with large amounts of water. Separate eyelids with fingers to ensure adequate flushing. Promptly call a physician.Skin contactRinse skin thoroughly with large amounts of water. Remove contaminated clothing and shoes and call a physician.InhalationImmediately relocate self or casualty to fresh air. If breathing is difficult, give cardiopulmonary resuscitation (CPR). Avoid mouth-to-mouth resuscitation.IngestionWash out mouth with water; Do NOT induce vomiting; call a physician.4.2 Most important symptoms and effects, both acute and delayedThe most important known symptoms and effects are described in the labelling (see section 2.2).4.3 Indication of any immediate medical attention and special treatment neededTreat symptomatically.5. FIRE FIGHTING MEASURES5.1 Extinguishing mediaSuitable extinguishing mediaUse water spray, dry chemical, foam, and carbon dioxide fire extinguisher.5.2 Special hazards arising from the substance or mixtureDuring combustion, may emit irritant fumes.5.3 Advice for firefightersWear self-contained breathing apparatus and protective clothing.6. ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency proceduresUse full personal protective equipment. Avoid breathing vapors, mist, dust or gas. Ensure adequate ventilation. Evacuate personnel to safe areas.Refer to protective measures listed in sections 8.6.2 Environmental precautionsTry to prevent further leakage or spillage. Keep the product away from drains or water courses.6.3 Methods and materials for containment and cleaning upAbsorb solutions with finely-powdered liquid-binding material (diatomite, universal binders); Decontaminate surfaces and equipment by scrubbing with alcohol; Dispose of contaminated material according to Section 13.7. HANDLING AND STORAGE7.1 Precautions for safe handlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.7.2 Conditions for safe storage, including any incompatibilitiesKeep container tightly sealed in cool, well-ventilated area. Keep away from direct sunlight and sources of ignition.Recommended storage temperature:Powder-20°C 3 years4°C 2 yearsIn solvent-80°C 6 months-20°C 1 monthShipping at room temperature if less than 2 weeks.7.3 Specific end use(s)No data available.8. EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parametersComponents with workplace control parametersThis product contains no substances with occupational exposure limit values.8.2 Exposure controlsEngineering controlsEnsure adequate ventilation. Provide accessible safety shower and eye wash station.Personal protective equipmentEye protection Safety goggles with side-shields.Hand protection Protective gloves.Skin and body protection Impervious clothing.Respiratory protection Suitable respirator.Environmental exposure controls Keep the product away from drains, water courses or the soil. Cleanspillages in a safe way as soon as possible.9. PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical propertiesAppearance White to off-white (Solid)Odor No data availableOdor threshold No data availablepH No data availableMelting/freezing point No data availableBoiling point/range No data availableFlash point No data availableEvaporation rate No data availableFlammability (solid, gas)No data availableUpper/lower flammability or explosive limits No data availableVapor pressure No data availableVapor density No data availableRelative density No data availableWater Solubility No data availablePartition coefficient No data availableAuto-ignition temperature No data availableDecomposition temperature No data availableViscosity No data availableExplosive properties No data availableOxidizing properties No data available9.2 Other safety informationNo data available.10. STABILITY AND REACTIVITY10.1 ReactivityNo data available.10.2 Chemical stabilityStable under recommended storage conditions.10.3 Possibility of hazardous reactionsNo data available.10.4 Conditions to avoidNo data available.10.5 Incompatible materialsStrong acids/alkalis, strong oxidising/reducing agents.10.6 Hazardous decomposition productsUnder fire conditions, may decompose and emit toxic fumes.Other decomposition products - no data available.11.TOXICOLOGICAL INFORMATION11.1 Information on toxicological effectsAcute toxicityClassified based on available data. For more details, see section 2Skin corrosion/irritationClassified based on available data. For more details, see section 2Serious eye damage/irritationClassified based on available data. For more details, see section 2Respiratory or skin sensitizationClassified based on available data. For more details, see section 2Germ cell mutagenicityClassified based on available data. For more details, see section 2CarcinogenicityIARC: No component of this product present at a level equal to or greater than 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.ACGIH: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by ACGIH.NTP: No component of this product present at a level equal to or greater than 0.1% is identified as a anticipated or confirmed carcinogen by NTP.OSHA: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by OSHA.Reproductive toxicityClassified based on available data. For more details, see section 2Specific target organ toxicity - single exposureClassified based on available data. For more details, see section 2Specific target organ toxicity - repeated exposureClassified based on available data. For more details, see section 2Aspiration hazardClassified based on available data. For more details, see section 2Additional informationRTECS No.: DA8340700Alopecia., Liver injury may occur., Kidney injury may occur., Nausea, Headache, Vomiting, bone marrow depressionThis information is based on our current knowledge. However the chemical, physical, and toxicological properties have not been completely investigated.12. ECOLOGICAL INFORMATION12.1 ToxicityNo data available.12.2 Persistence and degradabilityNo data available.12.3 Bioaccumlative potentialNo data available.12.4 Mobility in soilNo data available.12.5 Results of PBT and vPvB assessmentPBT/vPvB assessment unavailable as chemical safety assessment not required or not conducted.12.6 Other adverse effectsNo data available.13. DISPOSAL CONSIDERATIONS13.1 Waste treatment methodsProductDispose substance in accordance with prevailing country, federal, state and local regulations.Contaminated packagingConduct recycling or disposal in accordance with prevailing country, federal, state and local regulations.14. TRANSPORT INFORMATIONDOT (US)This substance is considered to be non-hazardous for transport.IMDGThis substance is considered to be non-hazardous for transport.IATAThis substance is considered to be non-hazardous for transport.15. REGULATORY INFORMATIONSARA 302 ComponentsNo chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.SARA 313 ComponentsNo chemicals in this material are subject to the reporting requirements of SARA Title III, Section 313.SARA 311/312 HazardsAcute Health Hazard, Chronic Health Hazard16. OTHER INFORMATIONCopyright 2018 MedChemExpress. The above information is correct to the best of our present knowledge but does not purport to be all inclusive and should be used only as a guide. The product is for research use only and for experienced personnel. It must only be handled by suitably qualified experienced scientists in appropriately equipped and authorized facilities. The burden of safe use of this material rests entirely with the user. MedChemExpress disclaims all liability for any damage resulting from handling or from contact with this product.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: tech@Address: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA。
[双(2-甲氧基乙基)胺]三氟化硫-安全技术说明书MSDS
![[双(2-甲氧基乙基)胺]三氟化硫-安全技术说明书MSDS](https://img.taocdn.com/s3/m/9f3464132e60ddccda38376baf1ffc4ffe47e2c4.png)
第一部分化学品及企业标识化学品中文名：[双(2-甲氧基乙基)胺]三氟化硫化学品英文名：Bis(2-methoxyethyl)aminosulfur trifluorideCAS No.：202289-38-1分子式：C6H14F3NO2S产品推荐及限制用途：工业及科研用途。
第二部分危险性概述紧急情况概述遇水放出易燃气体。
吞咽会中毒。
造成严重皮肤灼伤和眼损伤。
吸入会中毒。
GHS危险性类别遇水放出易燃气体的物质和混合物类别 2急性经口毒性类别 3皮肤腐蚀 / 刺激类别 1A急性吸入毒性类别 3标签要素：象形图：警示词：警告危险性说明：H261 遇水放出易燃气体H301 吞咽会中毒H314 造成严重皮肤灼伤和眼损伤H331 吸入会中毒●预防措施：—— P223 不得与水接触。
—— P231+P232 在惰性气体中操作。
防潮。
—— P280 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
—— P264 作业后彻底清洗。
—— P270 使用本产品时不要进食、饮水或吸烟。
—— P260 不要吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
—— P261 避免吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
—— P271 只能在室外或通风良好处使用。
●事故响应：—— P370+P378 火灾时：使用灭火器灭火。
—— P301+P310 如误吞咽：立即呼叫解毒中心/医生—— P330 漱口。
—— P301+P330+P331 如误吞咽：漱口。
不要诱导呕吐。
—— P303+P361+P353 如皮肤（或头发）沾染：立即脱掉所有沾染的衣服。
用水清洗皮肤/淋浴。
—— P363 沾染的衣服清洗后方可重新使用。
—— P304+P340 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。
—— P310 立即呼叫解毒中心/医生—— P305+P351+P338 如进入眼睛：用水小心冲洗几分钟。
如戴隐形眼镜并可方便地取出，取出隐形眼镜。
继续冲洗。
1-(3-二甲氨基丙基)-3-乙基碳二亚胺盐酸盐质量标准
1-(3-二甲氨基丙基)-3-乙基碳二亚胺盐酸盐质量标准1. 引言1.1 概述一-(3-二甲氨基丙基)-3-乙基碳二亚胺盐酸盐（简称EPH-HCl）是一种重要的有机化合物，具有广泛的应用价值。
EPH-HCl在医药领域被广泛用作药物原料，特别是作为治疗注意力缺陷多动障碍（ADHD）和嗜睡症（narcolepsy）的药物。
此外，EPH-HCl还可用于合成农药、染料、功能材料等领域。
1.2 文章结构本文共分为五个主要部分。
引言部分对文章的研究背景进行了概述，并介绍了文章的结构和目的。
第二部分将详细描述EPH-HCl的性质和用途，包括其化学性质和生物活性以及在不同领域中的应用情况。
第三部分将讨论制备EPH-HCl的方法和工艺流程，包括原料准备、反应条件和控制参数以及工艺流程简介。
第四部分将列出EPH-HCl的质量标准与检验方法，包括外观与纯度要求、含量测定方法以及杂质限量要求与检测方法。
最后，第五部分将总结本文的内容和研究结果，并对EPH-HCl的质量标准进行评价和展望。
1.3 目的本文旨在全面介绍一-(3-二甲氨基丙基)-3-乙基碳二亚胺盐酸盐的性质、制备方法及工艺流程，重点讨论其质量标准与检验方法。
通过对EPH-HCl的研究和分析，能够为相关领域的科学研究和工业应用提供参考依据，并促进该化合物在医药、农药、染料等领域的进一步开发和应用。
2. 一-(3-二甲氨基丙基)-3-乙基碳二亚胺盐酸盐的性质和用途2.1 化学性质：一-(3-二甲氨基丙基)-3-乙基碳二亚胺盐酸盐是一种白色结晶性固体，具有较好的溶解性。
它是一种非挥发性有机化合物，分子式为C10H24ClN3O，相对分子质量为217.77。
其熔点约为174-176摄氏度。
该化合物在常温下稳定，不易受热分解。
2.2 生物活性：一-(3-二甲氨基丙基)-3-乙基碳二亚胺盐酸盐是一种药物中间体，在药物领域有广泛的应用。
它是β受体阻滞剂的重要原料之一，可用于合成各类心血管系统药物。
德谷门冬双胰岛素注射液治疗2_型糖尿病临床效果及安全性探讨
DOI：10.16658/ki.1672-4062.2023.17.098德谷门冬双胰岛素注射液治疗2型糖尿病临床效果及安全性探讨林生，谢平，陈予福州市长乐区人民医院内分泌科，福建福州350200[摘要]目的研究德谷门冬双胰岛素注射液治疗2型糖尿病的临床效果及安全性。
方法选取于2022年7月—2023年4月福州市长乐区人民医院收治的2型糖尿病患者98例为研究对象，采用随机抓阄法分为两组，每组49例。
两组均联用常规降糖药物治疗，对照组采用甘精胰岛素注射液治疗，观察组采用德谷门冬双胰岛素注射液治疗。
对比两组临床治疗效果、临床症状好转时间和胰岛素用量情况、糖代谢指标、胰岛素功能指标、不良反应发生情况、心血管不良事件发生情况。
结果观察组总有效率高于对照组，差异有统计学意义（P<0.05）。
观察组尿酮体转阴时间、血糖达标时间、胰岛素用量均优于对照组，差异有统计学意义（P< 0.05）。
观察组空腹血糖、餐后2 h血糖、糖化血红蛋白均低于对照组，差异有统计学意义（P<0.05）。
观察组胰岛β细胞功能指数高于对照组，胰岛素抵抗指数、空腹胰岛素低于对照组，差异有统计学意义（P<0.05）。
两组恶心呕吐、倦怠乏力、低血糖总发生率比较，差异无统计学意义（P>0.05）。
两组心绞痛、心力衰竭总发生率比较，差异无统计学意义（P>0.05）。
结论德谷门冬双胰岛素注射液治疗2型糖尿病临床效果显著优于甘精胰岛素注射液，但是治疗安全性无显著变化。
[关键词] 2型糖尿病；德谷门冬双胰岛素注射液；不良反应；心血管不良事件[中图分类号] R59 [文献标识码] A [文章编号] 1672-4062（2023）09（a）-0098-04Discussion on the Clinical Effect and Safety of Insulin Degludec and Insu⁃lin Aspart Injection in the Treatment of Type 2 Diabetes MellitusLIN Sheng, XIE Ping, CHEN YuDepartment of Endocrinology, Changle District People's Hospital, Fuzhou, Fujian Province, 350200 China[Abstract] Objective To study the clinical effect and safety of insulin degludec and insulin aspart injection in the treatment of type 2 diabetes mellitus. Methods A total of 98 patients with type 2 diabetes admitted to Fuzhou Changle District People's Hospital from July 2022 to April 2023 were selected as the study objects and divided into two groups with 49 cases in each group by random lottery method. Both groups were treated with conventional hypoglycemic drugs, the control group was treated with insulin glargine injection, and the observation group was treated with Degu asparton double insulin injection. The clinical therapeutic effect, time of improvement of clinical symptoms, insulin dosage, glucose metabolism index, insulin function index, occurrence of adverse reactions and cardiovascular adverse events were compared between the two groups. Results The total effective rate of the observation group was higher than that of the control group, and the difference was statistically significant (P<0.05). The time of urine ketone body turning negative, blood glucose reaching standard and insulin dosage in observation group were better than those in control group, and the differences were statistically significant (P<0.05). Fasting plasma glucose, 2-hour postprandial blood glucose and glycated hemoglobin in the observation group were lower than those in the control group, and the differences were statistically significant (P<0.05). The function index of islet β cells in observation group was higher than that in control group, the insulin resistance index and fasting insulin was lower than that in control group, the dif⁃ference was statistically significant (P<0.05). There was no statistically significant difference in the total incidence of [作者简介]林生（1981-），男，本科，副主任医师，研究方向为糖尿病及其并发症的相关临床研究。
BMS-833923 1059734-66-5 GlpBio
Product Data SheetProduct Name:BMS-833923Cat. No.:GC13628Chemical PropertiesCas No.1059734-66-5Chemical Name N-[2-methyl-5-(methylaminomethyl)phenyl]-4-[(4-phenylquinazolin-2-yl)amino]benzamideCanonical SMILES CC1=C(C=C(C=C1)CNC)NC(=O)C2=CC=C(C=C2)NC3=NC4=CC=CC=C4C(=N3)C5=CC =CC=C5Formula C30H27N5O M.Wt473.57Solubility ≥47.4 mg/mL in DMSO, ≥5.14mg/mL in EtOH with ultrasonicand warming, <2.6 mg/mL in H2OStorage Store at -20°CGeneral tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request.Structure实验参考方法Cell experiment [1]:Product Data SheetCell lines OE19 (JROECL19) and OE33 (JROECL33) esophageal adenocarcinoma(EAC) cell linesPreparation method The solubility of this compound in DMSO is >47.4mg/mL. General tips for obtaining a higher concentration: Please warm the tube at 37 ℃ for 10 minutes and/or shake it in the ultrasonic bath for a while. Stock solution can be stored below -20℃ for several months.Reacting condition0 to 100 μM for 24 and 48 hrApplications In OE19 and OE33 cells, BMS-833923 (10 μM) inhibited cell proliferation with the IC50 of 10 μM. BMS-833923 (25 μM) completely inhibited cell proliferation. In OE19 and OE33 cells, treatment with 10 μM BMS-833923 resulted in 82 and 73.4% apoptotic cells, respectively.Animal experiment [2,3]:Animal models Medulloblastoma and pancreatic carcinoma xenografts mouse models, Male Sprague-Dawley rats with gastroesophageal reflux diseaseDosage form Oral administration, 10 mg/kgApplication In medulloblastoma and pancreatic carcinoma xenografts animal models, administration of BMS-833923 at single oral dose showed robust inhibition of Hh pathway. In a rat model with gastroesophageal reflux disease, administration of BMS-833923 (10 mg/kg/day) resulted in the decreased development of both Barrett esophagus and esophageal adenocarcinoma by 35.7%.Other notes Please test the solubility of all compounds indoor, and the actual solubility may slightly differ with the theoretical value. This is caused by an experimental system error and it is normal.References:[1]. Zaidi A H, Komatsu Y, Kelly L A, et al. Smoothened inhibition leads to decreased proliferation and induces apoptosis in esophageal adenocarcinoma cells. Cancer investigation, 2013, 31(7): 480-489. [2]. Gendreau S B, Hawkins D, Ho C P, et al. Abstract B192: Preclinical characterization of BMS‐833923 (XL139), a hedgehog (HH) pathway inhibitor in early clinical development. Molecular Cancer Therapeutics, 2009, 8(12 Supplement): B192-B192.[3].Gibson M K, Zaidi A H, Davison J M, et al. Prevention of Barrett esophagus and esophageal adenocarcinoma by smoothened inhibitor in a rat model of gastroesophageal reflux disease. Annals of surgery, 2013, 258(1): 82-88.BackgroundBMS-833923 is an orally bioavailable and selective antagonist of smoothened (SMO) with IC50 value of 5.8 nM in NIH3T3 cell line [1].The Hedgehog (Hh) signaling is a critical pathway involved in embryonic development and in tissue maintenance and repair in adults. It consists of the Hh ligands, the transmembrane receptors Patched 1 and 2, the G-protein- coupled receptor-like protein SMO and the glioma-associated oncogeneProduct Data Sheettranscription factors GLI1 to 3. The aberrant activation of Hh pathway, both mutational and epigenetic, is found to be associated with multiple aspects of tumorigenesis in various tumor cells. As a smoothened inhibitor, BMS-833923 can block the binding of cyclopamine (a naturally occurring SMO inhibitor) to SMO. It showed potent Hh pathway inhibitory activity with IC50 values at nanomolar in multiple cell-based assays. BMS-833923 also potently inhibited Hh pathway in medulloblastoma and pancreatic carcinoma xenograft models [1, 2 and 3].In vitro, BMS-833923 inhibited the expression of GLI1 and PTCH1 in cell lines expressing wild-type SMO or activated mutant SMO with IC50 values in the range from 6 to 35 nM. In the FACS-based binding assays, it does-dependently suppressed cyclopamine binding to SMO with IC50 value of 21 nM. In the esophageal adenocarcinoma cell lines OE19 and OE33, treatment of BMS-833923significantly reduced cell proliferation with IC50 values of both 10 μM. Besides that, BMS-833923 was found to inhibit the growth of multiple myeloma cells and the proportion of ALDH+ cancer stem cells. It also inhibited the growth of many other tumor cells derived from patients with hematological malignancies including ALL, AML and CML [3 and 4].In animal models with medulloblastoma and pancreatic carcinoma xenografts, administration of BMS-833923 at single oral dose showed robust inhibition of Hh pathway. In a rat model with gastroesophageal reflux disease, the administration of BMS-833923 at dose of 10 mg/kg/day resulted in the decreased development of both Barrett esophagus and esophageal adenocarcinoma by 35.7% [3 and 5].References:[1] Siu L L, Papadopoulos K P, Alberts S, et al. A first-in-human phase 1study of an oral hedgehog pathway antagonist, BMS-833923 (XL139), in subjects with advanced or metastatic solid tumors. Mol Cancer Ther, 2009, 8(12 Suppl): A55.[2] Justilien V, Fields A P. Molecular Pathways: Novel Approaches for Improved Therapeutic Targeting of Hedgehog Signaling in Cancer Stem Cells. Clinical Cancer Research, 2015, 21(3): 505-513.[3] Gendreau S B, Hawkins D, Ho C P, et al. Abstract B192: Preclinical characterization of BMS‐833923 (XL139), a hedgehog (HH) pathway inhibitor in early clinical development. Molecular Cancer Therapeutics, 2009, 8(12 Supplement): B192-B192.[4] Zaidi A H, Komatsu Y, Kelly L A, et al. Smoothened inhibition leads to decreased proliferation and induces apoptosis in esophageal adenocarcinoma cells. Cancer investigation, 2013, 31(7): 480-489.[5] Gibson M K, Zaidi A H, Davison J M, et al. Prevention of Barrett esophagus and esophageal adenocarcinoma by smoothened inhibitor in a rat model of gastroesophageal reflux disease. Annals of surgery, 2013, 258(1): 82-88.。
德谷门冬双胰岛素注射液治疗2_型糖尿病的疗效及安全性研究
DOI：10.16658/ki.1672-4062.2023.19.084德谷门冬双胰岛素注射液治疗2型糖尿病的疗效及安全性研究戴卉，张开凤，朱凤丽江苏省镇江市丹徒区人民医院内分泌科，江苏镇江212000[摘要]目的探讨德谷门冬双胰岛素注射液在2型糖尿病中的效果以及安全性。
方法选取2022年1月—2023年7月江苏省镇江市丹徒区人民医院收治的62例2型糖尿病患者为研究对象，按随机数表法分为对照组（n=31）和观察组（n=31）。
对照组患者接受门冬胰岛素30注射液治疗，观察组患者接受德谷门冬双胰岛素注射治疗。
对比两组患者临床疗效、血糖变化和不良反应发生率。
结果观察组治疗有效为96.77%，高于对照组的77.42%，差异有统计学意义（χ2=5.167，P=0.023）。
治疗前，两组患者血糖水平比较，差异无统计学意义（P>0.05）；治疗后，两组患者血糖水平均改善，且观察组血糖指标低于对照组，差异有统计学意义（P< 0.05）。
观察组不良反应发生率低与对照组，差异有统计学意义（P<0.05）。
结论德谷门冬双胰岛素的应用可以明显改善2型糖尿病患者血糖水平，疗效更为确切，且安全性更高，不会增加用药后不良反应。
[关键词] 2型糖尿病；德谷门冬双胰岛素；门冬胰岛素30注射液；安全性[中图分类号] R587 [文献标识码] A [文章编号] 1672-4062（2023）10（a）-0084-04Study on the Efficacy and Safety of Insulin Degludec and Insulin Aspart Injection in the Treatment of Type 2 Diabetes MellitusDAI Hui, ZHANG Kaifeng, ZHU FengliDepartment of Endocrinology, Zhenjiang Dantu District People's Hospital, Zhenjiang, Jiangsu Province, 212000 China [Abstract] Objective To explore the effect and safety of insulin degludec and insulin aspart injection in type 2 diabe⁃tes mellitus.Methods 62 patients of type 2 diabetes mellitus patients admitted to Zhenjiang Dantu District People's Hospital, Jiangsu Province from January 2022 to July 2023 were selected as study objects and divided into the control group (n=31) and the observation group (n=31) by taking the random number table method. The patients in the control group were treated with insulin aspart 30 injection and the patients in the observation group were treated with insulin degludec and insulin aspart injection. Compared the clinical efficacy, the changes in blood glucose and the incidence of adverse reactions between the two groups of patients.Results The treatment effectiveness of the observation group was 96.77%, which was higher than that of the control group, which was 77.42%, and the difference was statistically significant (χ2=5.167, P=0.023). There was no statistically significant difference in blood glucose levels between the two groups before treatment (P>0.05). After treatment, blood glucose levels improved in both groups, and the level of blood glucose in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). The incidence of adverse reactions in the observation group was lower than that in the control group, and the difference was statistically significant (P<0.05).Conclusion The application of insulin degludec and in⁃sulin aspart can significantly improve the blood glucose level of patients with type 2 diabetes mellitus, the efficacy is more accurate, and the safety is higher, and it will not increase the occurrence of adverse reactions after the use of medication.[作者简介]戴卉（1985-），女，本科，主治医师，研究方向为内分泌科。
过氧化二苯甲酰[51%＜含量≤100%,惰性固体含量≤48%]安全技术说明书MSDS
![过氧化二苯甲酰[51%＜含量≤100%,惰性固体含量≤48%]安全技术说明书MSDS](https://img.taocdn.com/s3/m/b68c8045f524ccbff021847d.png)
第一部分化学品及企业标识化学品中文名：过氧化二苯甲酰[51%＜含量≤100%,惰性固体含量≤48%]化学品英文名：dibenzoyl peroxide (more than 51%, and inert solid not more than 48%)化学品别名：-CAS No.：94-36-0EC No.：202-327-6分子式：C14H10O4第二部分危险性概述| 紧急情况概述固体。
遇热有火灾或爆炸危险。
跟皮肤接触可能会引起敏化作用。
对眼睛有严重刺激性。
对水生物有剧毒, 使用适当的容器, 以预防污染环境。
| GHS 危险性类别根据GB 30000-2013化学品分类和标签规范系列标准（参阅第十六部分），该产品分类如下：有机过氧化物，B型；皮肤敏化作用，类别1；眼损伤/眼刺激，类别2A；危害水生环境-急性毒性，类别1。
| 标签要素象形图警示词：危险危险信息：加热可能起火或爆炸，可能导致皮肤过敏反应，造成严重眼刺激，对水生生物毒性极大。
预防措施：远离热源、热表面、火花、明火以及其它点火源。
禁止吸烟。
只能在原包装中存放。
保持低温。
容器和接收设备接地和等势联接。
避免吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
作业后彻底清洗。
受沾染的工作服不得带出工作场地。
避免释放到环境中。
戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
事故响应：清洗后方可重新使用。
收集溢出物。
如发生皮肤刺激或皮疹：求医/就诊。
如仍觉眼刺激：求医/就诊。
如进入眼睛：用水小心冲洗几分钟。
如戴隐形眼镜并可方便地取出，取出隐形眼镜。
继续冲洗。
安全储存：存放在通风良好的地方。
防日晒。
分开存放。
废弃处置：按照地方/区域/国家/国际规章处置内装物/容器。
物理化学危险在包装件中可发生热爆炸。
健康危害吸入该物质可能会引起对健康有害的影响或呼吸道不适。
意外食入本品可能对个体健康有害。
皮肤直接接触可能导致皮肤过敏反应。
通过割伤、擦伤或病变处进入血液，可能产生全身损伤的有害作用。
苯二甲酰亚胺安全技术说明书(msds)
五、分子性质数据：1、摩尔折射率：37.422、摩尔体积（cm3/mol）：107.53、等张比容（90.2K）：291.04、表面张力（dyne/cm）：53.65、极化率（10-24cm3）：14.83
计算化学数据：
1.疏水参数计算参考值（XlogP）:无2.氢键供体数量:13.氢键受体数量:24.可旋转化学键数量:05.互变异构体数量:26.拓扑分子极性表面积46.27.重原子数量:118.表面电荷:09.复杂度:19010.同位素原子数量:011.确定原子立构中心数量:012.不确定原子立构中心数量:013.确定化学键立构中心数量:014.不确定化学键立构中心数量:015.共价键单元数量:1
供应商地址：
根据企业修改填写
供应商电话：
根据企业修改填写
供应商应急电话：
根据企业修改填写
供应商传真：
根据企业修改填写
供应商Email：
根据企业修改填写
第二部分：危险性概述
危险性类别：
第6.1类毒害品
侵入途径：
吸入食入经皮吸收
健康危害：
吸入、摄入或经皮肤吸收后对身体有害。对皮肤有轻微刺激作用，对眼睛、粘膜有刺激作用。
参考文献：
1. Green C R, Schumacher J N, Rodgman A. Beitr. Tabakforsch. Int., 2007, 22: 317-345.
2. LIDE D R. Editor-in-Chief, CRC Handbook of Chemistry and Physics on CD-ROM, Version 2003, CRC Press.
危险特性：
遇明火、高热可燃。受高热分解，放出有毒的烟气。
DMAC的MSDS
燃烧性：
可燃，可爆
建规火险分级：
闪点(℃)：
70℃开杯
自燃温度(℃)：
爆炸下限(V%)：
1．8％[100℃]
爆炸上限(V%)：
11．5％[160℃]
危险特性：
与空气接触能形成爆炸性混合物。与非氧化性无机酸、强酸类、氨、异氰酸酯类、酚类、85℃以上的甲酚卤化物不能配伍。能腐蚀某些塑料、橡胶和涂料。蒸气比空气重，易在低处聚集。封闭区域内的蒸气遇火能爆炸。蒸气能扩散到远处，遇点火源着火，并引起回燃。储存容器及其部件可能向四面八方飞射很远。
易燃性(红色)：2
反应活性(黄色)：0
燃烧(分解)产物：
稳定性：
聚合危害：
禁忌物：
四氯化碳、其它卤素化合物(与铁接Байду номын сангаас时)
灭火方法：
使用干粉、二氧化碳、泡沫灭火剂。如果该物质或被污染的流体进入水路，通知有潜在水体污染的下游用户，通知地方卫生、消防官员和污染控制部门。
包装与储运
危险性类别：
危险货物包装标志：
防
护
措
施
工程控制：
严禁烟火
呼吸系统防护：
NIOSH/OSHA 100ppm：供气式呼吸器。250ppm：连续供气式呼吸器。400ppm：自携式呼吸器、全面罩呼吸器。应急或有计划进入浓度未知区域，或处于立即危及生命或健康的状况：自携式正压全面罩呼吸器、供气式正压全面罩呼吸器辅之以辅助自携式正压呼吸器。逃生：装有机蒸气滤毒盒的空气净化式全面罩呼吸器(防毒面具)、自携式逃生呼吸器。
IMDG规则页码：
理
化
性
质
外观与性状：
无色、不易挥发的液体，带微弱氨味
主要用途：
乙酸乙酯胺MSDS
乙酸乙酯胺MSDS 1. 产品标识- 产品名称：乙酸乙酯胺- 化学名：N-ethylacetamide- CAS号：625-50-3- 分子式：C4H9NO2- 分子量：103.12g/mol2. 成分/组成信息- 主要成分：乙酸乙酯胺- 成分含量：100%3. 危险性概述- 乙酸乙酯胺可能对健康和环境造成危害。
- 本品有刺激性，可能对眼睛和皮肤造成刺激。
- 烟雾或气体吸入可能导致呼吸系统刺激。
- 请避免吸入，避免与皮肤、眼睛接触，并远离火源。
4. 急救措施- 吸入：将患者移到新鲜空气中，保持休息，如有呼吸困难，寻求医疗援助。
- 眼部接触：立即用大量清水冲洗受影响的眼部至少15分钟，同时寻求医疗援助。
- 皮肤接触：立即用肥皂和水彻底冲洗受影响的皮肤，如有刺激或不适，寻求医疗援助。
- 摄入：如患者意识清醒，立即给患者喝大量水，并催吐；寻求医疗援助。
5. 消防措施- 灭火方法：使用水雾、泡沫、二氧化碳或干粉灭火剂。
- 灭火注意事项：远离火源，防止燃烧物质扩散。
- 特殊危险：可能产生有毒气体。
6. 泄漏应急处理- 限制和清除泄漏物：避免接触泄漏物；用非反应性材料（如干砂或土）吸收泄漏物；将泄漏物收集并放入合适的。
- 个人防护措施：佩戴化学保护服、化学安全眼镜、化学防护手套和适当的呼吸保护装置。
7. 使用和储存注意事项- 使用注意事项：避免吸入、接触皮肤和眼睛。
- 储存条件：储存在干燥、凉爽和通风良好的地方；远离火源和氧化剂。
8. 接触控制/个人保护- 工程控制措施：确保良好的通风条件；使用局部排风设施。
- 个人防护装备：- 呼吸系统防护：如有吸入风险，佩戴合适的呼吸防护装置。
- 眼睛防护：佩戴密封的化学安全眼镜或面具。
- 皮肤防护：穿戴适当的化学防护服，并佩戴耐化学品的手套。
9. 环境控制- 环境控制措施：避免泄漏物进入水体或下水道。
- 指定的作业场所：提供足够的通风，并保持清洁。
10. 稳定性和反应活性- 稳定性：稳定，避免与强氧化剂接触。
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MSDS
1 Composition
7 Accident Release Measure
Product Name:BMS-833923
Chemical Name:
PROCEDURE(S) OF PERSONAL PRECAUTION(S)-Wear respirator, chemical safety goggles, rubber boots, and heavy
rubber gloves.METHODS FOR CLEANING UP-Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and
wash spill site after material pickup is complete.
Benzamide, N-[2-methyl-5-[(methylamino)methyl]phenyl]-4-[(4-phenyl-2-quinazolinyl)amino]-
CAS No.:1059734-66-5
8 Accident Release Measure
Appearance:light yellow to yellow(Solid)Formula:C30H27N5O 9 Toxicological Information
Solubility:
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
No data available.
p p p p 25°C: DMSO
2 Handling and Storage
10 Regulary Information
3 Stability and Reactivity
11Disposal Considerations
CLASSIFICATION- Substance not yet fully tested.SAFETY PHASES- 26-36 (In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.) 36/37/38 (Irritating to eyes,respiratory system and skin.)
STABILITY- Stable under normal handling conditions.HANDLING- Do not breathe dust. Avoid contact with eyes,
skin,and clothing.Avoid prolonged or repeated exposure.STORAGE- Store in a properly sealed container store at -20℃,shelflife is 2 years.
11 Disposal Considerations 4 Hazards Identification
12 Transport Information
5First Aid RID/ADR- Non-hazardous for road transport. IMDG- Non-hazardous for sea transport.IATA - Non-hazardous for air transport.
As specific country, federal, state and local environmental
regulations vary and change frequently we suggest you contact a local, authorized waste disposal contractor for adequate disposal.
Special indication of hazards to humans and the environment.Irritating to eyes, respiratory system and skin.
MATERIALS TO AVOID- Strong oxidizing agents.REACTIVITY- May emit toxic gasses like Carbon monoxide,Carbon dioxide, Nitrogen oxides upon thermal decomposition.
5 First Aid
13 Other Information
The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Medchemexpress LLC shall not be held liable for any damage resulting from h dli f t t ith th b d t
INHALATION- If inhaled, remove to fresh air. If not breathing give, artificial respiration. If breathing is difficult, give oxygen.SKIN CONTACT- In case of contact, immediately wash skin with
soap and copious amounts of water.EYE CONTACT- In case of contact, immediately flush eyes with
copious amounts of water for at least 15 minutes.INGESTION- If swallowed, wash out mouth with water provided person is conscious. Call a physician.
6 Fire Fighting Measures
handling or from contact with the above product.
EXTINGUISHING MEDIA Water spray- Carbon dioxide, dry chemical powder, or appropriate foam.
SPECIAL RISKS Specific Hazard(s)- Emits toxic fumes under fire conditions. SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS Wear self-contained breathing apparatus and protective clothing Caution: Not fully tested. For research purposes only
Medchemexpress LLC
to prevent contact with skin and eyes.
18 W i l k i n s o n W a y , P r i n c e t o n , N J 08540,U S A
E m a i l : i n f o @m e d c h e m e x p r e s s .c o m W e b : w w w .m e d c h e m e x p r e s s .c o m。