银杏酮酯滴丸对冠状动脉粥样硬化血液流变学指标的影响

银杏酮酯滴丸对冠状动脉粥样硬化血液流变学指标的影响刘利宏;曹华;黎鹏;戴功强;王春彬
【期刊名称】《四川医学》
【年(卷),期】2017(038)003
【摘要】目的观察银杏酮酯滴丸对冠状动脉粥样硬化患者血液流变学指标的影响.方法选择冠状动脉粥样硬化患者100例,随机分成联合治疗组及常规治疗组,每组50例,两组均给于常规药物治疗,联合治疗组采用常规药物基础上加用银杏酮酯滴丸口服,两组患者均连续治疗12周,比较两组患者治疗前后血液流变学指标.结果治疗前两组患者血液流变学指标(全血高切粘度、全血低切粘度、、血浆粘度、红细胞变形指数、纤维蛋白原)比较,差异无统计学意义(P>0.05),而常规治疗组及联合治疗组的血液流变学指标显著高于正常对照组,差异有统计学意义(P<0.05);治疗后联合治疗组的全血高切粘度、全血低切粘度、血浆粘度、红细胞变形指数、纤维蛋白原与治疗前相比显著降低(P<0.05)结论银杏酮酯滴丸可有效改善冠状动脉粥样硬化患者各项血液流变学指标,具有一定的临床应用价值.%Objective To observe the effect of Ginkgo biloba extract pills on hemorheology indexes in patients with coro-nary atherosclerosis. Methods 100 patients with coronary artery disease were randomly divided into two groups:the combined treatment group and the conventional treatment group,each group had 50 patients. Two groups were given conventional drug treat-ment. On the basis of conventional medicine,the combined treatment group was treated with Ginkgo biloba pills. Two groups of pa-tients were treated continuously for 12 weeks. The hemorheology indexes were compared between the two
groups before and after treatment. Results Before treatment,there was no statistically significant difference between the comparison of hemorheology inde-xes(whole blood viscosity,whole blood
viscosity,plasma viscosity,erythrocyte deformation index,fibrinogen)in two groups of pa-tients(P>0. 05). However,the hemorheology indexes of the conventional treatment group and the combined treatment group were significantly higher than those of the normal control group(P<0. 05). After treatment,the whole blood viscosity,whole blood low shear
viscosity,plasma viscosity,erythrocyte deformation index,fibrinogen of combined treatment group decreased significantly com-pared with before treatment(P<0. 05). Conclusion Ginkgo biloba pills can effectively improve the hemorheology indexes of pa-tients with coronary atherosclerosis,and has certain clinical application value.
【总页数】3页(P271-273)
【作者】刘利宏;曹华;黎鹏;戴功强;王春彬
【作者单位】眉山市人民医院心血管内科,四川眉山620010;重庆市第九人民医院,重庆400700;眉山市人民医院心血管内科,四川眉山620010;眉山市人民医院心血管内科,四川眉山620010;成都市第三人民医院,四川成都610016
【正文语种】中文
【中图分类】R541.4
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