PHARMACEUTICALLY ACCEPTABLE SALT, CRYSTAL FORM OF

专利名称：PHARMACEUTICALLY ACCEPTABLE SALT, CRYSTAL FORM OF AZABICYCLO
SUBSTITUTED TRIAZOLE DERIVATIVE AND
PREPARATION METHOD
发明人：WANG, Lin,王林,SHAO, Qiyun,邵启云,FENG, Jun,冯君,HE, Feng,贺峰,CAO, Xiaoli,曹笑立,DU,
Zhenxing,杜振兴
申请号：CN2019/092940
申请日：20190626
公开号：WO2020/001460A1
公开日：
20200102
专利内容由知识产权出版社提供
专利附图：
摘要：Provided are a pharmaceutically acceptable salt, a crystal form of an azabicyclo substituted triazole derivative and a preparation method therefor. In particular, provided are a pharmaceutically acceptable salt, a crystal form of a compound 1-(2-chloro-4-fluorophenyl)-3-(5-(methoxymethyl)-4-(6-methoxypyridine-3-yl)-4H-1,2,4-triazol-3-yl)-3-azabicyclo[3.1.0]hexane as shown in formula A, and a preparation method therefor. Relative to free bases, the pharmaceutically acceptable salt of the compound has a higher purity and an even better chemical stability, and is of great significance for developing a drug suitable for industrial production and having a good biological activity.
(A)
申请人：JIANGSU HENGRUI MEDICINE CO., LTD.,江苏恒瑞医药股份有限公司,SHANGHAI
HENGRUI PHARMACEUTICAL CO., LTD,上海恒瑞医药有限公司
地址：No. 7 Kunlunshan Road Economic and Technological Development Zone Lianyungang, Jiangsu 222047 CN,中国江苏省连云港市经济技术开发区昆仑山路7号, Jiangsu 222047 CN,No. 279 Wenjing Road Economic and Technological Development Zone, Minhang District Shanghai 200245 CN,中国上海市闵行经济技术开发区文井路279号, Shanghai 200245 CN
国籍：CN,CN,CN,CN
代理人：SHANGHAI BESHINING LAW OFFICE,上海弼兴律师事务所
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