CC-930_SDS_MedChemExpress

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磁力架说明书_Magnetic Stand Manual_MCE

1包装清单产品概述MCE 磁力架是磁珠产品专用配套设备，支持 MCE 全线磁珠类产品，内含强磁磁芯，可实现快速高效的分离。

MCE 磁力架 (200 μL / 2 mL / 15 mL ) 采用独特的三明治槽设计，磁条可抽出，可容纳 200 μL PCR 管，1.5 mL EP 管，2 mL EP 管，15 mL 离心管。

本产品适用于抗体纯化、免疫沉淀 (IP )、免疫共沉淀 (Co-IP )、细胞分选和核酸分离等实验。

2操作说明31. 将装有磁珠悬液的 EP 管/离心管置于磁力架对应的样品孔中，静置数分钟后磁珠被吸附聚集于管壁，溶液恢复澄清。

2. 用移液器或吸管从管底将溶液吸出，或小心倾倒出液体。

3. 抽去磁力条，加入复溶液体，轻缓震荡即可混合均匀，进行下一步操作。

注：磁性分离的时间与磁珠粒径有关，磁珠粒径越小，磁性分离时间越长。

此外，溶液的黏稠程度以及溶液的成分也会对磁性分离时间产生影响。

5注意事项1. 根据实验参数和样品体积不同，可调整磁芯位置或选用不同样式的磁力架。

2. 为减少操作过程中磁珠的损失，请将样品管底端插入磁力架底部的凹槽内。

当磁珠吸附在管壁上后，缓慢倾去上清，或用移液枪吸尽。

3. 由于磁力架有强大的磁场，请远离手机、电脑、手表、起博器、磁铁等易被磁力干扰的物体，尤其是刀具，以免对操作人员造成伤害。

4. 如需同时使用多个磁力架 (≥2 个) ，应分开放置，避免磁场之间产生干扰。

不要把多个磁棒放在一起，以防止夹伤。

5. 请勿与强酸、强碱等腐蚀性溶剂直接接触。

6. 请勿拆卸磁块。

7. 为保护外壳，请勿长时间暴露在阳光和紫外线下。

8. 为保持磁力架磁性，请勿置于高温和强外界磁场环境中。

9. 使用后请及时清洁，妥善放置在干燥环境中。

Magnetic StandMedChemExpress MedChemExpress 400-820-3792 电话: ************ 传真: ************Email: t *********************MCE Hotline: 400-820-3792Contents HY-K0200Magnetic Stand 200 μL-2 mL-15 mL。

CIL56-SDS-MedChemExpress

Inhibitors, Agonists, Screening LibrariesSafety Data Sheet Revision Date:Jan.-07-2019Print Date:Jan.-07-20191. PRODUCT AND COMPANY IDENTIFICATION1.1 Product identifierProduct name :CIL56Catalog No. :HY-112063CAS No. :300802-28-21.2 Relevant identified uses of the substance or mixture and uses advised againstIdentified uses :Laboratory chemicals, manufacture of substances.1.3 Details of the supplier of the safety data sheetCompany:MedChemExpress USATel:609-228-6898Fax:609-228-5909E-mail:sales@1.4 Emergency telephone numberEmergency Phone #:609-228-68982. HAZARDS IDENTIFICATION2.1 Classification of the substance or mixtureGHS Classification in accordance with 29 CFR 1910 (OSHA HCS)Acute toxicity, Oral (Category 4), H302Acute aquatic toxicity (Category 1), H400Chronic aquatic toxicity (Category 1), H4102.2 GHS Label elements, including precautionary statementsPictogramSignal word No data availableHazard statement(s)H302 Harmful if swallowed.H410 Very toxic to aquatic life with long lasting effectsPrecautionary statement(s)P264 Wash skin thoroughly after handling.P270 Do not eat, drink or smoke when using this product.P273 Avoid release to the environment.P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor ⁄ physician if you feel unwell.P330 Rinse mouth.P391 Collect spillage.P501 Dispose of contents ⁄ container to an approved waste disposal plant.2.3 Other hazardsNone.3. COMPOSITION/INFORMATION ON INGREDIENTS3.1 SubstancesSynonyms:NoneFormula:C23H27N3O5S2Molecular Weight:489.61CAS No. :300802-28-24. FIRST AID MEASURES4.1 Description of first aid measuresEye contactRemove any contact lenses, locate eye-wash station, and flush eyes immediately with large amounts of water. Separate eyelids with fingers to ensure adequate flushing. Promptly call a physician.Skin contactRinse skin thoroughly with large amounts of water. Remove contaminated clothing and shoes and call a physician.InhalationImmediately relocate self or casualty to fresh air. If breathing is difficult, give cardiopulmonary resuscitation (CPR). Avoid mouth-to-mouth resuscitation.IngestionWash out mouth with water; Do NOT induce vomiting; call a physician.4.2 Most important symptoms and effects, both acute and delayedThe most important known symptoms and effects are described in the labelling (see section 2.2).4.3 Indication of any immediate medical attention and special treatment neededTreat symptomatically.5. FIRE FIGHTING MEASURES5.1 Extinguishing mediaSuitable extinguishing mediaUse water spray, dry chemical, foam, and carbon dioxide fire extinguisher.5.2 Special hazards arising from the substance or mixtureDuring combustion, may emit irritant fumes.5.3 Advice for firefightersWear self-contained breathing apparatus and protective clothing.6. ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency proceduresUse full personal protective equipment. Avoid breathing vapors, mist, dust or gas. Ensure adequate ventilation. Evacuate personnel to safe areas.Refer to protective measures listed in sections 8.6.2 Environmental precautionsTry to prevent further leakage or spillage. Keep the product away from drains or water courses.6.3 Methods and materials for containment and cleaning upAbsorb solutions with finely-powdered liquid-binding material (diatomite, universal binders); Decontaminate surfaces and equipment by scrubbing with alcohol; Dispose of contaminated material according to Section 13.7. HANDLING AND STORAGE7.1 Precautions for safe handlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.7.2 Conditions for safe storage, including any incompatibilitiesKeep container tightly sealed in cool, well-ventilated area. Keep away from direct sunlight and sources of ignition.Recommended storage temperature:Powder-20°C 3 years4°C 2 yearsIn solvent-80°C 6 months-20°C 1 monthShipping at room temperature if less than 2 weeks.7.3 Specific end use(s)No data available.8. EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parametersComponents with workplace control parametersThis product contains no substances with occupational exposure limit values.8.2 Exposure controlsEngineering controlsEnsure adequate ventilation. Provide accessible safety shower and eye wash station.Personal protective equipmentEye protection Safety goggles with side-shields.Hand protection Protective gloves.Skin and body protection Impervious clothing.Respiratory protection Suitable respirator.Environmental exposure controls Keep the product away from drains, water courses or the soil. Cleanspillages in a safe way as soon as possible.9. PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical propertiesAppearance White to off-white (Solid)Odor No data availableOdor threshold No data availablepH No data availableMelting/freezing point No data availableBoiling point/range No data availableFlash point No data availableEvaporation rate No data availableFlammability (solid, gas)No data availableUpper/lower flammability or explosive limits No data availableVapor pressure No data availableVapor density No data availableRelative density No data availableWater Solubility No data availablePartition coefficient No data availableAuto-ignition temperature No data availableDecomposition temperature No data availableViscosity No data availableExplosive properties No data availableOxidizing properties No data available9.2 Other safety informationNo data available.10. STABILITY AND REACTIVITY10.1 ReactivityNo data available.10.2 Chemical stabilityStable under recommended storage conditions.10.3 Possibility of hazardous reactionsNo data available.10.4 Conditions to avoidNo data available.10.5 Incompatible materialsStrong acids/alkalis, strong oxidising/reducing agents.10.6 Hazardous decomposition productsUnder fire conditions, may decompose and emit toxic fumes.Other decomposition products - no data available.11.TOXICOLOGICAL INFORMATION11.1 Information on toxicological effectsAcute toxicityClassified based on available data. For more details, see section 2Skin corrosion/irritationClassified based on available data. For more details, see section 2Serious eye damage/irritationClassified based on available data. For more details, see section 2Respiratory or skin sensitizationClassified based on available data. For more details, see section 2Germ cell mutagenicityClassified based on available data. For more details, see section 2CarcinogenicityIARC: No component of this product present at a level equal to or greater than 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.ACGIH: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by ACGIH.NTP: No component of this product present at a level equal to or greater than 0.1% is identified as a anticipated or confirmed carcinogen by NTP.OSHA: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by OSHA.Reproductive toxicityClassified based on available data. For more details, see section 2Specific target organ toxicity - single exposureClassified based on available data. For more details, see section 2Specific target organ toxicity - repeated exposureClassified based on available data. For more details, see section 2Aspiration hazardClassified based on available data. For more details, see section 212. ECOLOGICAL INFORMATION12.1 ToxicityNo data available.12.2 Persistence and degradabilityNo data available.12.3 Bioaccumlative potentialNo data available.12.4 Mobility in soilNo data available.12.5 Results of PBT and vPvB assessmentPBT/vPvB assessment unavailable as chemical safety assessment not required or not conducted.12.6 Other adverse effectsNo data available.13. DISPOSAL CONSIDERATIONS13.1 Waste treatment methodsProductDispose substance in accordance with prevailing country, federal, state and local regulations.Contaminated packagingConduct recycling or disposal in accordance with prevailing country, federal, state and local regulations.14. TRANSPORT INFORMATIONDOT (US)This substance is considered to be non-hazardous for transport.IMDGUN number: 3077 Class: 9 Packing group: III EMS-No: F-A, S-FProper shipping name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.Marine pollutant: Marine pollutantIATAUN number: 3077 Class: 9 Packing group: IIIProper shipping name: Environmentally hazardous substance, solid, n.o.s.15. REGULATORY INFORMATIONSARA 302 Components:No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.SARA 313 Components:This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis)reporting levels established by SARA Title III, Section 313.SARA 311/312 Hazards:Acute Health Hazard16. OTHER INFORMATIONCopyright 2019 MedChemExpress. The above information is correct to the best of our present knowledge but does not purport to be all inclusive and should be used only as a guide. The product is for research use only and for experienced personnel. It must only be handled by suitably qualified experienced scientists in appropriately equipped and authorized facilities. The burden of safe use of this material rests entirely with the user. MedChemExpress disclaims all liability for any damage resulting from handling or from contact with this product.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: tech@Address: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA。

T0070907_LCMS_04465_MedChemExpress

=====================================================================Acq. Operator : Li Shan(LCMS-02) Seq. Line : 50Acq. Instrument : HY-LCMS-02 Location : P1-C-01Injection Date : 5/15/2015 12:20:58 PM Inj : 1Inj Volume : 3.000 µlAcq. Method : D:\AGLIENT 1260\DATA\20150515\20150515 2015-05-15 08-47-06\100-1000MS+3MIN-1.5_(0.02%FA).MLast changed : 5/15/2015 8:47:06 AM by Li Shan(LCMS-02)Analysis Method : D:\AGLIENT 1260\METHOD\BL30-90A,210NM(RP-HPLC).MLast changed : 5/15/2015 3:12:48 PM by Li Shan(LCMS-02)(modified after loading)M ethod Info : HPLC Catalog No : HY-13202 Batch#04465 A-RP-132Additional Info : Peak(s) manually integratedmin0.51 1.52 2.53mAU20040060080010001200DAD1 C, Sig=254,4 Ref=off (D:\AGLIENT...0\DATA\20150515\20150515 2015-05-15 08-47-06\CPK2015-515-04465.D)1.362 1.462 1.8372.110=====================================================================Area Percent Report=====================================================================Sorted By : SignalMultiplier : 1.0000Dilution : 1.0000Do not use Multiplier & Dilution Factor with ISTDsSignal 1: DAD1 C, Sig=254,4 Ref=offPeak RetTime Type Width Area Height Area# [min] [min] [mAU*s] [mAU] %----|-------|----|-------|----------|----------|--------|1 1.362 MM 0.0528 1.80688 5.70622e-1 0.03642 1.462 MM 0.0554 4955.89258 1490.00452 99.88903 1.837 MM 0.0677 2.64214 6.50008e-1 0.05334 2.110 MM 0.0641 1.05738 2.74959e-1 0.0213Totals : 4961.39899 1491.50011=====================================================================*** End of Report ***===========================================================Acq. Operator : Li Shan(LCMS-02) Seq. Line : 50Acq. Instrument : HY-LCMS-02 Location : P1-C-01Injection Date : 5/15/2015 12:20:58 PM Inj : 1Inj Volume : 3.000 µlAcq. Method : D:\AGLIENT 1260\DATA\20150515\20150515 2015-05-15 08-47-06\100-1000MS+3MIN-1.5_(0.02%FA).MLast changed : 5/15/2015 8:47:06 AM by Li Shan(LCMS-02)Analysis Method : D:\AGLIENT 1260\METHOD\BL30-90A,210NM(RP-HPLC).MLast changed : 5/15/2015 3:14:15 PM by Li Shan(LCMS-02)(modified after loading)M ethod Info : HPLC Catalog No : HY-13202 Batch#04465 A-RP-132Additional Info : Peak(s) manually integratedmin 0.51 1.52 2.530100000200000300000400000500000600000700000800000MSD1 TIC, MS File (D:\AGLIENT 1260\DATA\20150515\20150515 2015-05-15 08-47-06\CPK2015-515-04465.D) ES-API, Pos, Sc1.466MS Signal: MSD1 TIC, MS File, ES-API, Pos, Scan, Frag: 50 Spectra averaged over upper half of peaks. Noise Cutoff: 1000 counts. Reportable Ion Abundance: > 10%.Retention Mol. WeightTime (MS) MS Area or Ion1.466 4473754 280.00 I279.00 I278.00 Im/z 100200300400500600020406080100*MSD1 SPC, time=1.434:1.507 of D:\AGLIENT 1260\DATA\20150515\20150515 2015-05-15 08-47-06\CPK2015-515-04465.D ES-API Max: 432781279.0 278.0 *** End of Report ***。

CC-930_DataSheet_MedChemExpress

Inhibitors, Agonists, Screening Libraries Data SheetBIOLOGICAL ACTIVITY:CC–930 is a potent JNK1/JNK2/JNK3 inhibitor with IC 50 values of 61/7/6 nM, respectively, and used for the treatment of fibrotic and infammatory indications.IC50 & Target: IC50: 61 nM (JNK1), 7 nM (JNK2), 6 nM (JNK3)[1]In Vitro: CC–930 inhibits the formation of phospho–cJun in human PBMC stimulated by phorbol–12–myristate–13–acetate and phytohemeagglutinin (IC 50=1 μM)[1]. CC–930 (1–2 μM) substantially reduces hepatocyte apoptosis and necrosis, abrogates apoptosis and necrosis in FC–loaded WT hepatocytes [2]. CC–930 blocks the JNK pathway that is activated by pro–fibrotic cytokinesin systemic sclerosis [3].In Vivo: CC–930 (10 and 30 mg/kg, p.o.) inhibits the production of TNFa by 23% and 77% in the acute rat LPS–induced TNFa production PK–PD model [1]. CC–930 (150 mg/kg) prevents the development of fibrosis in different models, but can also induce theregression of pre–existing fibrosis [3].PROTOCOL (Extracted from published papers and Only for reference)Cell Assay:[3]Systemic sclerosis (SSc) fibroblasts are incubated with 1 μM CC–930 in 96–well plates for 20 h. Then MTT is added at a final concentration of 1 mg/mL, and the cells are further incubated at 37°C for 4 h. Mock–treated fibroblasts are used as controls, and all other results are normalised to untreated cells.Animal Administration:[3]To evaluate the regression of fibrosis on inhibition of JNK, a modified model of bleomycin–induced dermal fibrosis is used. In this model, treatment is initiated 3 weeks after the beginning of the challenge with bleomycin, when significant dermal fibrosis is already established. The outcome of six different groups with a total number of 40 mice is analysed. The first group of mice receive subcutaneous injections of NaCl for 6 weeks. The second group is injected for 3 weeks with bleomycin followed by injections of NaCl for another 3 weeks to analyse the degree of fibrosis before treatment, and to control the spontaneous regression of fibrosis. The third group of mice is killed after 6 weeks of injections with bleomycin. The fourth and the fifth group are treated with CC–930 at doses of 50 mg/kg and 150 mg/kg for the last 3 weeks of continuous challenge with bleomycin for 6 weeks. The sixth group is a positive control group consisting of mice challenged with bleomycin for 6 weeks and treated in parallel with imatinib at doses of 50 mg/kg for the last 3 weeks.References:[1]. Plantevin Krenitsky V, et al. Discovery of CC–930, an orally active anti–fibrotic JNK inhibitor. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1433–8.[2]. Gan LT, et al. Hepatocyte free cholesterol lipotoxicity results from JNK1–mediated mitochondrial injury and is HMGB1 and TLR4–dependent. J Hepatol.2014 Dec;61(6):1376–84.[3]. Reich N, et al. Jun N–terminal kinase as a potential molecular target for prevention and treatment of dermal fibrosis. Ann Rheum Dis. 2012 May;Product Name:CC–930Cat. No.:HY-15495CAS No.:899805-25-5Molecular Formula:C 21H 23F 3N 6O 2Molecular Weight:448.44Target:JNK Pathway:MAPK/ERK Pathway Solubility:DMSO: ≥ 33 mg/mL71(5):737–45.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: tech@Address: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA。

分子印迹 - 固相萃取法选择性分离大黄酸的研究

分子印迹 - 固相萃取法选择性分离大黄酸的研究段玉清;张海晖;徐菲菲;闫永胜;李金凤;梁凯【期刊名称】《林产化学与工业》【年(卷),期】2009(29)5【摘要】以大黄酸(RH)为印迹分子,大孔壳聚糖为功能载体,甲基丙烯酸为功能单体,制备大黄酸的分子印迹聚合物(MIP).通过固相萃取和HPLC评价MIP对大黄酸的选择性分离.结果MIP与非印迹聚合物(NIP)相比,对大黄酸表现出较高的选择性和识别性.使大黄酸的质量分数由16.55%提高到95.12%.并利用Freundlich和Langmuir等温吸附模型描述MIP对大黄酸吸附的平衡等温线.%A molecularly imprinted polymer (MIP) was prepared using rhein (RH) as imprinted molecule,macroporous chitosan beads as functional matrix and methacrylic acid as functional monomer.The obtained molecularly imprinted polymers were evaluated by solid phase extraction and HPLC with respect to their selective recognition ability for rhein.MIP exhibited higher selectivity and recognition ability for rhein in a mixture of RH-MIP than non-imprinted polymer (NIP),and the content of rhein was increased from 16.55 % to 95.12 %.Langmuir and Freundlich adsorption models were applied to describe the equilibrium isotherms of rhein adsorbed by MIP.【总页数】6页(P35-40)【作者】段玉清;张海晖;徐菲菲;闫永胜;李金凤;梁凯【作者单位】江苏大学食品与生物工程学院,江苏镇江212013;江苏大学食品与生物工程学院,江苏镇江212013;江苏大学食品与生物工程学院,江苏镇江212013;江苏大学食品与生物工程学院,江苏镇江212013;江苏大学食品与生物工程学院,江苏镇江212013;江苏大学食品与生物工程学院,江苏镇江212013【正文语种】中文【中图分类】TQ351.0【相关文献】1.应用分子印迹-固相萃取法提取中药活性成分非瑟酮 [J], 李礼;胡树国;何锡文;李文友;陈朗星;张玉奎2.分子印迹磁固相萃取法测定饮料中咖啡因含量 [J], 李艳;石亚亭;李德蓉;蒋淑敏;张也;杜黎明3.分子印迹固相萃取法提取花生壳中木犀草素 [J], 肖淑娟;李红霞;于守武4.利用分子印迹固相萃取法进行竹红菌素精制的研究 [J], 史文玉;张同存5.左氧氟沙星分子印迹膜固相萃取选择性分离氧氟沙星 [J], 邴乃慈; 许振良; 王学军; 杨座国因版权原因，仅展示原文概要，查看原文内容请购买。

Gelucire-14-44-SDS-MedChemExpress

Inhibitors, Agonists, Screening LibrariesSafety Data Sheet Revision Date:Nov.-23-2018Print Date:Nov.-23-20181. PRODUCT AND COMPANY IDENTIFICATION1.1 Product identifierProduct name :Gelucire 14/44Catalog No. :HY-Y1892CAS No. :121548-04-71.2 Relevant identified uses of the substance or mixture and uses advised againstIdentified uses :Laboratory chemicals, manufacture of substances.1.3 Details of the supplier of the safety data sheetCompany:MedChemExpress USATel:609-228-6898Fax:609-228-5909E-mail:sales@1.4 Emergency telephone numberEmergency Phone #:609-228-68982. HAZARDS IDENTIFICATION2.1 Classification of the substance or mixtureNot a hazardous substance or mixture.2.2 GHS Label elements, including precautionary statementsNot a hazardous substance or mixture.2.3 Other hazardsNone.3. COMPOSITION/INFORMATION ON INGREDIENTS3.1 SubstancesSynonyms:NoneFormula:N/AMolecular Weight:N/ACAS No. :121548-04-74. FIRST AID MEASURES4.1 Description of first aid measuresEye contactRemove any contact lenses, locate eye-wash station, and flush eyes immediately with large amounts of water. Separate eyelids with fingers to ensure adequate flushing. Promptly call a physician.Skin contactRinse skin thoroughly with large amounts of water. Remove contaminated clothing and shoes and call a physician.InhalationImmediately relocate self or casualty to fresh air. If breathing is difficult, give cardiopulmonary resuscitation (CPR). Avoid mouth-to-mouth resuscitation.IngestionWash out mouth with water; Do NOT induce vomiting; call a physician.4.2 Most important symptoms and effects, both acute and delayedThe most important known symptoms and effects are described in the labelling (see section 2.2).4.3 Indication of any immediate medical attention and special treatment neededTreat symptomatically.5. FIRE FIGHTING MEASURES5.1 Extinguishing mediaSuitable extinguishing mediaUse water spray, dry chemical, foam, and carbon dioxide fire extinguisher.5.2 Special hazards arising from the substance or mixtureDuring combustion, may emit irritant fumes.5.3 Advice for firefightersWear self-contained breathing apparatus and protective clothing.6. ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency proceduresUse full personal protective equipment. Avoid breathing vapors, mist, dust or gas. Ensure adequate ventilation. Evacuate personnel to safe areas.Refer to protective measures listed in sections 8.6.2 Environmental precautionsTry to prevent further leakage or spillage. Keep the product away from drains or water courses.6.3 Methods and materials for containment and cleaning upAbsorb solutions with finely-powdered liquid-binding material (diatomite, universal binders); Decontaminate surfaces and equipment by scrubbing with alcohol; Dispose of contaminated material according to Section 13.7. HANDLING AND STORAGE7.1 Precautions for safe handlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.7.2 Conditions for safe storage, including any incompatibilitiesKeep container tightly sealed in cool, well-ventilated area. Keep away from direct sunlight and sources of ignition.Recommended storage temperature:Pure form-20°C 3 years4°C 2 yearsIn solvent-80°C 6 months-20°C 1 monthShipping at room temperature if less than 2 weeks.7.3 Specific end use(s)No data available.8. EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parametersComponents with workplace control parametersThis product contains no substances with occupational exposure limit values.8.2 Exposure controlsEngineering controlsEnsure adequate ventilation. Provide accessible safety shower and eye wash station.Personal protective equipmentEye protection Safety goggles with side-shields.Hand protection Protective gloves.Skin and body protection Impervious clothing.Respiratory protection Suitable respirator.Environmental exposure controls Keep the product away from drains, water courses or the soil. Cleanspillages in a safe way as soon as possible.9. PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical propertiesAppearance White to off-white (Oil)Odor No data availableOdor threshold No data availablepH No data availableMelting/freezing point No data availableBoiling point/range No data availableFlash point No data availableEvaporation rate No data availableFlammability (solid, gas)No data availableUpper/lower flammability or explosive limits No data availableVapor pressure No data availableVapor density No data availableRelative density No data availableWater Solubility No data availablePartition coefficient No data availableAuto-ignition temperature No data availableDecomposition temperature No data availableViscosity No data availableExplosive properties No data availableOxidizing properties No data available9.2 Other safety informationNo data available.10. STABILITY AND REACTIVITY10.1 ReactivityNo data available.10.2 Chemical stabilityStable under recommended storage conditions.10.3 Possibility of hazardous reactionsNo data available.10.4 Conditions to avoidNo data available.10.5 Incompatible materialsStrong acids/alkalis, strong oxidising/reducing agents.10.6 Hazardous decomposition productsUnder fire conditions, may decompose and emit toxic fumes.Other decomposition products - no data available.11.TOXICOLOGICAL INFORMATION11.1 Information on toxicological effectsAcute toxicityClassified based on available data. For more details, see section 2Skin corrosion/irritationClassified based on available data. For more details, see section 2Serious eye damage/irritationClassified based on available data. For more details, see section 2Respiratory or skin sensitizationClassified based on available data. For more details, see section 2Germ cell mutagenicityClassified based on available data. For more details, see section 2CarcinogenicityIARC: No component of this product present at a level equal to or greater than 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.ACGIH: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by ACGIH.NTP: No component of this product present at a level equal to or greater than 0.1% is identified as a anticipated or confirmed carcinogen by NTP.OSHA: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by OSHA.Reproductive toxicityClassified based on available data. For more details, see section 2Specific target organ toxicity - single exposureClassified based on available data. For more details, see section 2Specific target organ toxicity - repeated exposureClassified based on available data. For more details, see section 2Aspiration hazardClassified based on available data. For more details, see section 212. ECOLOGICAL INFORMATION12.1 ToxicityNo data available.12.2 Persistence and degradabilityNo data available.12.3 Bioaccumlative potentialNo data available.12.4 Mobility in soilNo data available.12.5 Results of PBT and vPvB assessmentPBT/vPvB assessment unavailable as chemical safety assessment not required or not conducted.12.6 Other adverse effectsNo data available.13. DISPOSAL CONSIDERATIONS13.1 Waste treatment methodsProductDispose substance in accordance with prevailing country, federal, state and local regulations.Contaminated packagingConduct recycling or disposal in accordance with prevailing country, federal, state and local regulations.14. TRANSPORT INFORMATIONDOT (US)This substance is considered to be non-hazardous for transport.IMDGThis substance is considered to be non-hazardous for transport.IATAThis substance is considered to be non-hazardous for transport.15. REGULATORY INFORMATIONSARA 302 Components:No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.SARA 313 Components:This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.SARA 311/312 Hazards:No SARA Hazards.Massachusetts Right To Know Components:No components are subject to the Massachusetts Right to Know Act.Pennsylvania Right To Know Components:No components are subject to the Pennsylvania Right to Know Act.New Jersey Right To Know Components:No components are subject to the New Jersey Right to Know Act.California Prop. 65 Components:This product does not contain any chemicals known to State of California to cause cancer, birth defects, or anyother reproductive harm.16. OTHER INFORMATIONCopyright 2018 MedChemExpress. The above information is correct to the best of our present knowledge but does not purport to be all inclusive and should be used only as a guide. The product is for research use only and for experienced personnel. It must only be handled by suitably qualified experienced scientists in appropriately equipped and authorized facilities. The burden of safe use of this material rests entirely with the user. MedChemExpress disclaims all liability for any damage resulting from handling or from contact with this product.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: tech@Address: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA。

SPACE_peptide_SDS_MedChemExpress

Inhibitors, Agonists, Screening LibrariesSafety Data Sheet Revision Date:May-24-2017Print Date:May-24-20171. PRODUCT AND COMPANY IDENTIFICATION1.1 Product identifierProduct name :SPACE peptideCatalog No. :HY-P0123CAS No. :None1.2 Relevant identified uses of the substance or mixture and uses advised againstIdentified uses :Laboratory chemicals, manufacture of substances.1.3 Details of the supplier of the safety data sheetCompany:MedChemExpress USATel:609-228-6898Fax:609-228-5909E-mail:sales@1.4 Emergency telephone numberEmergency Phone #:609-228-68982. HAZARDS IDENTIFICATION2.1 Classification of the substance or mixtureNot a hazardous substance or mixture.2.2 GHS Label elements, including precautionary statementsNot a hazardous substance or mixture.2.3 Other hazardsNone.3. COMPOSITION/INFORMATION ON INGREDIENTS3.1 SubstancesSynonyms:AC⁻TGSTQHQ⁻CG,Disulfide Bridge 2–10Formula:C40H63N15O17S2Molecular Weight:1090.17CAS No. :None4. FIRST AID MEASURES4.1 Description of first aid measuresEye contactRemove any contact lenses, locate eye-wash station, and flush eyes immediately with large amounts of water. Separate eyelids with fingers to ensure adequate flushing. Promptly call a physician.Skin contactRinse skin thoroughly with large amounts of water. Remove contaminated clothing and shoes and call a physician.InhalationImmediately relocate self or casualty to fresh air. If breathing is difficult, give cardiopulmonary resuscitation (CPR). Avoid mouth-to-mouth resuscitation.IngestionWash out mouth with water; Do NOT induce vomiting; call a physician.4.2 Most important symptoms and effects, both acute and delayedThe most important known symptoms and effects are described in the labelling (see section 2.2).4.3 Indication of any immediate medical attention and special treatment neededTreat symptomatically.5. FIRE FIGHTING MEASURES5.1 Extinguishing mediaSuitable extinguishing mediaUse water spray, dry chemical, foam, and carbon dioxide fire extinguisher.5.2 Special hazards arising from the substance or mixtureDuring combustion, may emit irritant fumes.5.3 Advice for firefightersWear self-contained breathing apparatus and protective clothing.6. ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency proceduresUse full personal protective equipment. Avoid breathing vapors, mist, dust or gas. Ensure adequate ventilation. Evacuate personnel to safe areas.Refer to protective measures listed in sections 8.6.2 Environmental precautionsTry to prevent further leakage or spillage. Keep the product away from drains or water courses.6.3 Methods and materials for containment and cleaning upAbsorb solutions with finely-powdered liquid-binding material (diatomite, universal binders); Decontaminate surfaces and equipment by scrubbing with alcohol; Dispose of contaminated material according to Section 13.7. HANDLING AND STORAGE7.1 Precautions for safe handlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.7.2 Conditions for safe storage, including any incompatibilitiesKeep container tightly sealed in cool, well-ventilated area. Keep away from direct sunlight and sources of ignition.Recommended storage temperature:Powder-20°C 3 years4°C 2 yearsIn solvent-80°C 6 months-20°C 1 monthShipping at room temperature if less than 2 weeks.7.3 Specific end use(s)No data available.8. EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parametersComponents with workplace control parametersThis product contains no substances with occupational exposure limit values.8.2 Exposure controlsEngineering controlsEnsure adequate ventilation. Provide accessible safety shower and eye wash station.Personal protective equipmentEye protection Safety goggles with side-shields.Hand protection Protective gloves.Skin and body protection Impervious clothing.Respiratory protection Suitable respirator.Environmental exposure controls Keep the product away from drains, water courses or the soil. Cleanspillages in a safe way as soon as possible.9. PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical propertiesAppearance White to off-white (Solid)Odor No data availableOdor threshold No data availablepH No data availableMelting/freezing point No data availableBoiling point/range No data availableFlash point No data availableEvaporation rate No data availableFlammability (solid, gas)No data availableUpper/lower flammability or explosive limits No data availableVapor pressure No data availableVapor density No data availableRelative density No data availableWater Solubility No data availablePartition coefficient No data availableAuto-ignition temperature No data availableDecomposition temperature No data availableViscosity No data availableExplosive properties No data availableOxidizing properties No data available9.2 Other safety informationNo data available.10. STABILITY AND REACTIVITY10.1 ReactivityNo data available.10.2 Chemical stabilityStable under recommended storage conditions.10.3 Possibility of hazardous reactionsNo data available.10.4 Conditions to avoidNo data available.10.5 Incompatible materialsStrong acids/alkalis, strong oxidising/reducing agents.10.6 Hazardous decomposition productsUnder fire conditions, may decompose and emit toxic fumes.Other decomposition products - no data available.11.TOXICOLOGICAL INFORMATION11.1 Information on toxicological effectsAcute toxicityClassified based on available data. For more details, see section 2Skin corrosion/irritationClassified based on available data. For more details, see section 2Serious eye damage/irritationClassified based on available data. For more details, see section 2Respiratory or skin sensitizationClassified based on available data. For more details, see section 2Germ cell mutagenicityClassified based on available data. For more details, see section 2CarcinogenicityIARC: No component of this product present at a level equal to or greater than 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.ACGIH: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by ACGIH.NTP: No component of this product present at a level equal to or greater than 0.1% is identified as a anticipated or confirmed carcinogen by NTP.OSHA: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by OSHA.Reproductive toxicityClassified based on available data. For more details, see section 2Specific target organ toxicity - single exposureClassified based on available data. For more details, see section 2Specific target organ toxicity - repeated exposureClassified based on available data. For more details, see section 2Aspiration hazardClassified based on available data. For more details, see section 212. ECOLOGICAL INFORMATION12.1 ToxicityNo data available.12.2 Persistence and degradabilityNo data available.12.3 Bioaccumlative potentialNo data available.12.4 Mobility in soilNo data available.12.5 Results of PBT and vPvB assessmentPBT/vPvB assessment unavailable as chemical safety assessment not required or not conducted.12.6 Other adverse effectsNo data available.13. DISPOSAL CONSIDERATIONS13.1 Waste treatment methodsProductDispose substance in accordance with prevailing country, federal, state and local regulations.Contaminated packagingConduct recycling or disposal in accordance with prevailing country, federal, state and local regulations.14. TRANSPORT INFORMATIONDOT (US)This substance is considered to be non-hazardous for transport.IMDGThis substance is considered to be non-hazardous for transport.IATAThis substance is considered to be non-hazardous for transport.15. REGULATORY INFORMATIONSARA 302 Components:No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.SARA 313 Components:This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.SARA 311/312 Hazards:No SARA Hazards.Massachusetts Right To Know Components:No components are subject to the Massachusetts Right to Know Act.Pennsylvania Right To Know Components:No components are subject to the Pennsylvania Right to Know Act.New Jersey Right To Know Components:No components are subject to the New Jersey Right to Know Act.California Prop. 65 Components:This product does not contain any chemicals known to State of California to cause cancer, birth defects, or anyother reproductive harm.16. OTHER INFORMATIONCopyright 2017 MedChemExpress. The above information is correct to the best of our present knowledge but does not purport to be all inclusive and should be used only as a guide. The product is for research use only and for experienced personnel. It must only be handled by suitably qualified experienced scientists in appropriately equipped and authorized facilities. The burden of safe use of this material rests entirely with the user. MedChemExpress disclaims all liability for any damage resulting from handling or from contact with this product.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: tech@Address: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA。

美国Medchemexpress化合物库(小分子库)_Medchemexpress_(MCE中国)

美国Medchemexpress化合物库（小分子库）-原装进口，现货供
应，提供组合定制服务
品牌：Medchemexpress （MCE）
保存条件：-20℃
供应商：MCE中国
数量：大量
保质期：2年
Size：
Pre-dissolved DMSO/Solid（Or dry solid）
100 uL/well (10 mM solution)
200 uL/well (10 mM solution)
MedChemExpress (MCE)专注于各种抑制剂、调节剂、API、天然产物及化合物库，总部位于美国新泽西。

MCE经过十年努力已成为全球生物活性小分子领域的一流供应商。

MedChemExpress(MCE)产品涵盖近20个热门研究领域，1000多个细分靶点，超过3000个现货抑制剂、拮抗剂和激动剂。

相关的应用成果已发表于Nature、Cell等国际知名杂志，在全球20余个国家地区设有代理机构。

上海皓元生物医药科技有限公司(MCE 中国) 是MedChemExpress (MCE) 亚洲总代理。

MCE化合物库涵盖20余种不同的类型，超过2500个化合物，进口原装，
现货供应，提供详实的生物活性信息、化学结构信息、质控图谱（NMR和HPLC 等）。

还可根据您的实际研究需要，为您度身定制任意组合、规格、布板的特殊化合物库。

/screening-libraries.html
现有特色化合物库有：。

CCK8中文说明书_MedChemExpress

WST-8 是 MTT 的一种升级替代产品，和 MTT 或其它 MTT 类似产品，如 XTT 、MTS 等相比有明显的优点。

第一，MTT 被线粒体内的一些脱氢酶还原生成的 formazan 不是水溶性的，需要有特定的溶剂来溶解；而 WST-8 和 XTT 、MTS 产生的 formazan 都是水溶性的，可以省去后续的溶解步骤。

第二，WST-8 产生的 formazan 比 XTT 和 MTS 产生的 formazan 更易溶解。

第三，WST-8 比 XTT 和 MTS 更加稳定，使实验结果更可靠。

第四，WST-8 和 MTT 、XTT 等相比线性范围更宽，灵敏度更高，并且更加稳定。

WST-8 对细胞无明显毒性。

加入 CCK-8 溶液显色后，可以在不同时间反复用酶标仪读板，检测时间更加灵活，便于确定最佳测定时间。

产品编号HY-K0301-100T HY-K0301-500T HY-K0301-3000T HY-K0301-12000T包装1 mL 5 mL 5 mL × 6(5 mL × 6) × 4产品名称Cell Counting Kit-8Cell Counting Kit-8Cell Counting Kit-8Cell Counting Kit-8Cell Counting Kit-81包装清单产品概述Cell Counting Kit-8，简称 CCK-8 试剂盒，是一种基于 WST-8 而广泛应用于细胞增殖和细胞毒性的快速、高灵敏度、无放射性的比色检测试剂盒。

CCK-8 溶液可以直接加入到细胞样品中，不需要预配各种成分。

WST-8 在电子耦合试剂存在的情况下，可以被线粒体内的一些脱氢酶还原生成橙黄色的formazan (参考图1) 。

细胞增殖越多越快，则颜色越深；细胞毒性越大，则颜色越浅。

对于同样的细胞，颜色的深浅 (生成的 formazan 量) 和细胞数目呈线性关系 (图2) 。

CCCP-SDS-MedChemExpress

Inhibitors, Agonists, Screening LibrariesSafety Data Sheet Revision Date:Oct.-08-2018Print Date:Oct.-08-20181. PRODUCT AND COMPANY IDENTIFICATION1.1 Product identifierProduct name :CCCPCatalog No. :HY-100941CAS No. :555-60-21.2 Relevant identified uses of the substance or mixture and uses advised againstIdentified uses :Laboratory chemicals, manufacture of substances.1.3 Details of the supplier of the safety data sheetCompany:MedChemExpress USATel:609-228-6898Fax:609-228-5909E-mail:sales@1.4 Emergency telephone numberEmergency Phone #:609-228-68982. HAZARDS IDENTIFICATION2.1 Classification of the substance or mixtureGHS Classification in accordance with 29 CFR 1910 (OSHA HCS)Acute toxicity, Oral (Category 3), H301Acute toxicity, Inhalation (Category 3), H331Acute toxicity, Dermal (Category 3), H311Skin irritation (Category 2), H315Eye irritation (Category 2A), H319Specific target organ toxicity - single exposure (Category 3), Respiratory system, H3352.2 GHS Label elements, including precautionary statementsPictogramSignal word DangerHazard statement(s)H301 + H311 + H331 Toxic if swallowed, in contact with skin or if inhaledH315 Causes skin irritation.H319 Causes serious eye irritation.H335 May cause respiratory irritation.Precautionary statement(s)P261 Avoid breathing dust ⁄ fume ⁄ gas ⁄ mist ⁄ vapours ⁄ spray.P264 Wash skin thoroughly after handling.P270 Do not eat, drink or smoke when using this product.P271 Use only outdoors or in a well-ventilated area.P280 Wear eye protection ⁄ face protection.P280 Wear protective gloves ⁄ protective clothing.P301 + P310 + P330 IF SWALLOWED: Immediately call a POISON CENTER or doctor ⁄ physician. Rinse mouth.P302 + P352 IF ON SKIN: Wash with plenty of soap and water.P302 + P352 + P312 IF ON SKIN: Wash with plenty of soap and water. Call a POISON CENTER or doctor ⁄ physician if you feel unwell.P304 + P340 + P311 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or doctor ⁄ physician.P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.Continue rinsing.P332 + P313 If skin irritation occurs: Get medical advice ⁄ attention.P337 + P313 If eye irritation persists: Get medical advice ⁄ attention.P361 Remove ⁄Take off immediately all contaminated clothing.P403 + P233 Store in a well-ventilated place. Keep container tightly closed.P405 Store locked up.P501 Dispose of contents ⁄ container to an approved waste disposal plant2.3 Other hazardsNone.3. COMPOSITION/INFORMATION ON INGREDIENTS3.1 SubstancesSynonyms:Carbonyl cyanide 3-chlorophenylhydrazone;Carbonyl Cyanide m-Chlorophenylhydrazone Formula:C9H5ClN4Molecular Weight:204.62CAS No. :555-60-24. FIRST AID MEASURES4.1 Description of first aid measuresEye contactRemove any contact lenses, locate eye-wash station, and flush eyes immediately with large amounts of water. Separate eyelids with fingers to ensure adequate flushing. Promptly call a physician.Skin contactRinse skin thoroughly with large amounts of water. Remove contaminated clothing and shoes and call a physician.InhalationImmediately relocate self or casualty to fresh air. If breathing is difficult, give cardiopulmonary resuscitation (CPR). Avoid mouth-to-mouth resuscitation.IngestionWash out mouth with water; Do NOT induce vomiting; call a physician.4.2 Most important symptoms and effects, both acute and delayedThe most important known symptoms and effects are described in the labelling (see section 2.2).4.3 Indication of any immediate medical attention and special treatment neededTreat symptomatically.5. FIRE FIGHTING MEASURES5.1 Extinguishing mediaSuitable extinguishing mediaUse water spray, dry chemical, foam, and carbon dioxide fire extinguisher.5.2 Special hazards arising from the substance or mixtureDuring combustion, may emit irritant fumes.5.3 Advice for firefightersWear self-contained breathing apparatus and protective clothing.6. ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency proceduresUse full personal protective equipment. Avoid breathing vapors, mist, dust or gas. Ensure adequate ventilation. Evacuate personnel to safe areas.Refer to protective measures listed in sections 8.6.2 Environmental precautionsTry to prevent further leakage or spillage. Keep the product away from drains or water courses.6.3 Methods and materials for containment and cleaning upAbsorb solutions with finely-powdered liquid-binding material (diatomite, universal binders); Decontaminate surfaces and equipment by scrubbing with alcohol; Dispose of contaminated material according to Section 13.7. HANDLING AND STORAGE7.1 Precautions for safe handlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.7.2 Conditions for safe storage, including any incompatibilitiesKeep container tightly sealed in cool, well-ventilated area. Keep away from direct sunlight and sources of ignition.Recommended storage temperature:Powder-20°C 3 years4°C 2 yearsIn solvent-80°C 6 months-20°C 1 monthShipping at room temperature if less than 2 weeks.7.3 Specific end use(s)No data available.8. EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parametersComponents with workplace control parametersThis product contains no substances with occupational exposure limit values.8.2 Exposure controlsEngineering controlsEnsure adequate ventilation. Provide accessible safety shower and eye wash station.Personal protective equipmentEye protection Safety goggles with side-shields.Hand protection Protective gloves.Skin and body protection Impervious clothing.Respiratory protection Suitable respirator.Environmental exposure controls Keep the product away from drains, water courses or the soil. Cleanspillages in a safe way as soon as possible.9. PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical propertiesAppearance Light yellow to yellow (Solid) Odor No data availableOdor threshold No data availablepH No data availableMelting/freezing point No data availableBoiling point/range No data availableFlash point No data availableEvaporation rate No data availableFlammability (solid, gas)No data availableUpper/lower flammability or explosive limits No data availableVapor pressure No data availableVapor density No data availableRelative density No data availableWater Solubility No data availablePartition coefficient No data availableAuto-ignition temperature No data availableDecomposition temperature No data availableViscosity No data availableExplosive properties No data availableOxidizing properties No data available9.2 Other safety informationNo data available.10. STABILITY AND REACTIVITY10.1 ReactivityNo data available.10.2 Chemical stabilityStable under recommended storage conditions.10.3 Possibility of hazardous reactionsNo data available.10.4 Conditions to avoidNo data available.10.5 Incompatible materialsStrong acids/alkalis, strong oxidising/reducing agents.10.6 Hazardous decomposition productsUnder fire conditions, may decompose and emit toxic fumes.Other decomposition products - no data available.11.TOXICOLOGICAL INFORMATION11.1 Information on toxicological effectsAcute toxicityClassified based on available data. For more details, see section 2Skin corrosion/irritationClassified based on available data. For more details, see section 2Serious eye damage/irritationClassified based on available data. For more details, see section 2Respiratory or skin sensitizationClassified based on available data. For more details, see section 2Germ cell mutagenicityClassified based on available data. For more details, see section 2CarcinogenicityIARC: No component of this product present at a level equal to or greater than 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.ACGIH: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by ACGIH.NTP: No component of this product present at a level equal to or greater than 0.1% is identified as a anticipated or confirmed carcinogen by NTP.OSHA: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by OSHA.Reproductive toxicityClassified based on available data. For more details, see section 2Specific target organ toxicity - single exposureClassified based on available data. For more details, see section 2Specific target organ toxicity - repeated exposureClassified based on available data. For more details, see section 2Aspiration hazardClassified based on available data. For more details, see section 2Additional informationRTECS No.: FG5600000To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.This information is based on our current knowledge. However the chemical, physical, and toxicological properties have not been completely investigated.12. ECOLOGICAL INFORMATION12.1 ToxicityNo data available.12.2 Persistence and degradabilityNo data available.12.3 Bioaccumlative potentialNo data available.12.4 Mobility in soilNo data available.12.5 Results of PBT and vPvB assessmentPBT/vPvB assessment unavailable as chemical safety assessment not required or not conducted.12.6 Other adverse effectsNo data available.13. DISPOSAL CONSIDERATIONS13.1 Waste treatment methodsProductDispose substance in accordance with prevailing country, federal, state and local regulations.Contaminated packagingConduct recycling or disposal in accordance with prevailing country, federal, state and local regulations.14. TRANSPORT INFORMATIONDOT (US)UN number: 2811Class: 6.1Packing group: IIIProper shipping name: Toxic solids, organic, n.o.s. (3-Aminopyridine-2-carboxaldehyde thiosemicarbazone)Reportable Quantity (RQ):Poison Inhalation Hazard: NoIMDGUN number: 2811Class: 6.1Packing group: IIIEMS-No: F-A, S-AProper shipping name: TOXIC SOLID, ORGANIC, N.O.S. (3-Aminopyridine-2-carboxaldehyde thiosemicarbazone)IATAUN number: 2811Class: 6.1Packing group: IIIProper shipping name: Toxic solid, organic, n.o.s. (3-Aminopyridine-2-carboxaldehyde thiosemicarbazone)15. REGULATORY INFORMATIONSARA 302 ComponentsNo chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.SARA 313 ComponentsNo chemicals in this material are subject to the reporting requirements of SARA Title III, Section 313.SARA 311/312 HazardsAcute Health Hazard, Chronic Health Hazard16. OTHER INFORMATIONCopyright 2018 MedChemExpress. The above information is correct to the best of our present knowledge but does not purport to be all inclusive and should be used only as a guide. The product is for research use only and for experienced personnel. It must only be handled by suitably qualified experienced scientists in appropriately equipped and authorized facilities. The burden of safe use of this material rests entirely with the user. MedChemExpress disclaims all liability for any damage resulting from handling or from contact with this product.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: tech@Address: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA。

人体内源性代谢物化合物库

MedChem ExpressInhibitors, Agonists, Screening LibrariesMedChemExpress USACompound Screening LibraryHandling InstructionsLockedTel: 609-228-6898Tech E-mail:tech@ Fax: 609-228-5909 Sale E-mail: sales@ Address: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USARecognize Me!96-Well Format Racks for Sample Storage TubesLidLockOur sample rack uses a LidLock lever to secure the top of the rack. The LidLock can prevent the tubes in racks from falling out if the rack is inverted or dropped. Simply push the LidLock in the desired direction as marked by the arrows to open or lock the rack.RackCodeEach 96 sample-rack has a “RackCode ” linear barcode located on the side which can be used to easily distinguish different racks.Compound Technical Documents:Each compound library is shipped with a flash drive containing an Excel file that describes the detailed information of compounds in your library. The disk also contains the SDF , COA for every compound, this general handling instructions and compound layout for each screening library.The Excel file details the following information:RackCode, Cat. No., Product Name, Plate Location, VialCode, CAS No., M.Wt, Target, Saltdata, Information, Smiles, Solubility, Method of Analysis, Batch No., Quantity, URL and Pathway.Chemical structure information for each compound is contained in the relevant SDF files.If you have any questions, please contact our technical support via Email at: tech@ .VialCodeCompounds can be identified quickly by scanning the 2D barcode with an HD barcode scanner. Each 96-well format sample storage tube contains a "VialCode " 2D barcode located on the base of the vial. Using the 2D barcode, you can look up the corresponding compound information for the vial in electronic files or the provided hard copy.1 Can we centrifuge the whole rack?Yes. It is advised to centrifuge all of the samples before experimental use. This can prevent the compound from adhering to the tube wall or even the tube gap and can reduce experimental error.2 How can I use the 2D barcode on the bottom of vial?Use an HD barcode scanner to scan the barcode, and then find the corresponding compound information in the Excel or the provided hard copy.3 How do I dissolve my compounds (dry solid)?Add the relevant solvent (DMSO, Ethanol etc.) specified by your ordered format (100 μL or 250 μL) and dilute the solution to a concentration of 10 mM.4 What are the appropriate compound storage conditions?For dry solid compounds, store at 4°C.For solutions, store at -80°C.For some special compounds, specific handling instructions are provided.5 After receiving the compound library, the ice box has melted, will this affect the efficacy of the compound?MCE products are primarily chemical synthesis products which are not temperature sensitive. The ice boxes inside of the packages are used to prevent the occurrence of extreme temperatures during the process of transportation, and a melted icebox will not affect the reagent quality. After transit, the icebox is no longer needed.Frequently Asked Questions:。

校准品名称产品描述规格货号17校准品与质控品

校准品名称产品描述规格货号多项校准血清level2特种蛋白多项校准血清胆红素校准品(BIL’S)转铁蛋白校准品(TRF’S)总胆汁酸校准品(TBA’S)腺苷脱氨酶校准品(ADA’S)α-L-岩藻糖苷酶校准品(AFU’S)5′-核苷酸酶校准品(5′-NT’S)单胺氧化酶校准品(MAO’S)胱抑素C校准品(Cys-C’S)N-乙酰-β-D-氨基葡萄糖苷酶校准品(NAG’S)尿微量白蛋白校准品(MALB’S)β2-微球蛋白校准品(BMG’S)脑脊液及尿蛋白校准品(CSF/UP’S)高/低密度脂蛋白胆固醇校准品(HDL/LDL-C’S)载脂蛋白A1/B校准品(APOA1/B’S)脂蛋白a校准品(Lp(a)’S)同型半胱氨酸校准品(HCY’S)糖化血清蛋白校准品(GSP’S)糖化血红蛋白校准品(HbA1c%’S)二氧化碳校准品(CO2’S)抗链球菌溶血素“O”校准品(ASO’S)类风湿因子校准品(RF’S)超敏C-反应蛋白校准品(HS-CRP’S)肌红蛋白校准品（Mb’S）包含多种生化检测项目包含IgA、IgG、IgM、C3、C4、PALB、TRF包含TBIL和DBIL包含HDL-C和LDL-C包含APOA1和APOB 1套1套1支1支1支1支1支1支1支1套1支1支1支1支1支1套1套1套1支1套1支1支1支1套1套CC1201CC1105CC1123CC1154CC1126CC1127CC1128CC1129CC1130CC1134CC1135CC1136CC1137CC1138CC1141CC1142CC1143CC1145CC1146CC1147CC1150CC1151CC1152CC1153CC115617校准品与质控品校准品名称产品描述规格货号肌钙蛋白I校准品（cTnI’S）血管紧张素转化酶校准品（ACE’S）血氨校准品（AMM’S）α1-微球蛋白校准品（α1-MG’S）铁蛋白校准品（Fer’S）视黄醇结合蛋白校准品（RBP’S）D-二聚体校准品（DD’S）1套1套1套1套1套1套1套CC1157CC1165CC1166CC1167CC1168CC1169CC1170包含多种生化检测项目包含IgA、IgG、IgM、C3、C4、PALB、TRF包含CK/CKMB包含CHO、TG、HDL、LDL包含APOA1和APOB多项质控血清特种蛋白多项质控血清α-L-岩藻糖苷酶质控品(AFU)5′-核苷酸酶质控品(5′-NT)单胺氧化酶质控品(MAO)腺苷脱氨酶质控品(ADA)胱抑素C质控品(Cys-C)N-乙酰-β-D-氨基葡萄糖苷酶质控品(NAG)尿微量白蛋白质控品(MALB)β2-微球蛋白质控品(BMG)肌酸激酶/肌酸激酶同工酶质控品(CK/CKMB)脂类质控品载脂蛋白A1/B质控品(APOA1/B)脂蛋白a质控品(Lp(a))同型半胱氨酸质控品(HCY)LEVEL 2LEVEL 3LEVEL 1LEVEL 2LEVEL 1LEVEL 2LEVEL 1LEVEL 2LEVEL 1LEVEL 2LEVEL 1LEVEL 2LEVEL 1LEVEL 2LEVEL 1LEVEL 2LEVEL 1LEVEL 2LEVEL 1LEVEL 2LEVEL 2LEVEL 3LEVEL 1LEVEL 2LEVEL 1LEVEL 2LEVEL 1LEVEL 2CC2201CC2301CC2105CC2205CC2128CC2228CC2129CC2229CC2130CC2230CC2127CC2227CC2134CC2234CC2135CC2235CC2136CC2236CC2137CC2237CC2354CC2255CC2355CC2142CC2242CC2143CC2243CC2145CC22451支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支质控品名称产品描述浓度水平货号规格18校准品与质控品质控品名称产品描述浓度水平货号规格19糖化血清蛋白质控品(GSP)糖化血红蛋白质控品(HbA1c%)抗链球菌溶血素“O”质控品(ASO)类风湿因子质控品(RF)超敏C-反应蛋白质控品(HS-CRP)肌红蛋白质控品（Mb ）肌钙蛋白I 质控品（cTnI ）血管紧张素转化酶质控品（ACE ）血氨质控品（AMM ）α1-微球蛋白质控品（α1-MG ）铁蛋白质控品（Fer ）视黄醇结合蛋白质控品（RBP ）D-二聚体质控品（DD ）LEVEL 1LEVEL 2LEVEL 1LEVEL 2LEVEL 1LEVEL 2LEVEL 1LEVEL 2LEVEL 1LEVEL 2LEVEL 1LEVEL 2LEVEL 1LEVEL 2LEVEL 1LEVEL 2LEVEL 1LEVEL 2LEVEL 1LEVEL 2LEVEL 1LEVEL 2LEVEL 1LEVEL 2LEVEL 1LEVEL 2CC2146CC2246CC2147CC2247CC2151CC2251CC2152CC2252CC2153CC2253CC2156CC2256CC2157CC2257CC2165CC2265CC2166CC2266CC2167CC2267CC2168CC2268CC2169CC2269CC2170CC22701支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支1支校准品与质控品。

ce-sds方法优化及其在抗体纯度检测中的应用与流程

ce-sds方法优化及其在抗体纯度检测中的应用与流程CE-SDS (Capillary Electrophoresis - Sodium Dodecyl Sulfate) 是一种常用的蛋白质分析技术，通常用于测定抗体的纯度和相关蛋白质的杂质含量。

以下是CE-SDS方法的优化和在抗体纯度检测中的应用和流程。

优化CE-SDS方法：1. 样品制备：抗体样品需要经过还原、热变性和去糖基化等处理步骤，以确保蛋白质在电泳过程中的准确分离。

此外，还需要考虑抗体浓度和载带缓冲液的选择等因素。

2. 电泳条件：需要优化电场强度、电泳缓冲液的pH等条件，以确保蛋白质在电泳毛细管中的迁移速度和准确分离度。

3. 标准品制备：准备适当的蛋白质标准品，可用于校准和定量分析。

4. 检测方法：选择适当的检测方法，如荧光检测、紫外检测等，以实现对蛋白质的敏感和准确检测。

CE-SDS方法在抗体纯度检测中的应用与流程：1. 样品准备：将抗体样品经过还原剂和变性缓冲液处理，以去除可能的杂质和聚集体。

2. 电泳操作：将经过处理的样品和蛋白质标准品分别加载到电泳芯片中，通过电场驱动蛋白质在毛细管中的迁移。

3. 分离和检测：在电泳过程中，蛋白质根据其大小和电荷进行分离。

在电泳结束后，使用适当的检测方法对蛋白质进行定性和定量分析。

4. 数据分析：根据蛋白质的迁移距离和标准品的浓度，计算样品中抗体的纯度和杂质含量。

总结：CE-SDS方法是一种高效、灵敏的抗体纯度检测技术，通过优化方法和流程，可以实现对抗体样品的准确分离和定量分析。

这种方法能够帮助研究人员评估抗体的纯度，并提供高质量的抗体样品，以保证后续研究的准确性和可靠性。