重复经颅磁刺激治疗 MECT 所致记忆障碍对照研究

重复经颅磁刺激治疗 MECT 所致记忆障碍对照研究
郭昕;王跃升;龚毅
【期刊名称】《临床心身疾病杂志》
【年(卷),期】2015(21)2
【摘要】Objective To explore the efficacy of repetitive transcranial magnetic stimulation (rTMS) for memory disorders due to modified electroconvulsive therapy (MECT) .Methods Fifty‐two schizophrenics who developed memory disorders in 2 weeks after MECT were randomly assigned to two groups ,rTMSs given to research group and pseudo‐rTMSs to control group for 4 weeks .Memory function rehabilitations were assessed with the Wechsler Memory Scale (WMS) .Results Since the 1st day treatment each dimension score of the WMS of both groups heightened continuously (P<0.05 or 0.01) , those at the ends of the 1st and 2nd week did more significantly in research than control group (P<0.05 or 0 .01);full recovery rate of memory function was significantly higher in research than control group at the end of the 2nd week (69.2% vs
15.4% ,χ2 =15.44 , P<0.01) .Conclusion The rTMS has an evident effect on memory disorders due to M ECT in schizophrenics .%目的：探讨重复经颅磁刺激治疗无抽搐电休克所致记忆障碍的疗效。

方法将52例经无抽搐电休克治疗2周后出现记忆障碍的精神分裂症患者随机分为两组，研究组予以重复经颅磁刺激治疗，对照组予以假性重复经颅磁刺激治疗，观察4周。

采用韦氏记忆量表评估患者记忆功能恢复状况。

结果治疗后两组韦氏记忆量表各维度评分均较治疗第1d呈
持续性升高（ P＜0.05或0.01），治疗第1周、2周末研究组各维度评分较对照组升高更显著（ P＜0.05或0.01）；治疗第2周末研究组记忆功能完全恢复率69.2％，对照组为15.4％，研究组显著高于对照组（χ2＝15.44，P＜0.01）。

结论重复经颅磁刺激治疗精神分裂症患者行无抽搐电休克治疗后所致的记忆障碍效果显著。

【总页数】3页(P20-22)
【作者】郭昕;王跃升;龚毅
【作者单位】650101 云南·昆明昆明市精神病医院;650101 云南·昆明昆明市精神病医院;650101 云南·昆明昆明市精神病医院
【正文语种】中文
【中图分类】R749,749.054
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