慢性淋巴细胞性白血病患者的皮肤鳞状细胞癌的转移率和死亡率增加

慢性淋巴细胞性白血病患者的皮肤鳞状细胞癌的转移率和死亡
率增加
Mehrany; K.; Weenig; R.; H.; Lee; K.K.
【期刊名称】《《世界核心医学期刊文摘：皮肤病学分册》》
【年(卷),期】2006(2)3
【摘要】In patients with chronic lymphocytic leukemia, squamous cell carcinoma behaves aggressively. Our purpose was to compare squamous cell carcinoma metastasis and mortality between patients with chronic lymphocytic leukemia and control subjects. Medical records were assessed retrospectively for 28 patients with chronic lymphocytic leukemia who underwent surgical excision of cutaneous squamous cell carcinoma and for 56 matched control subjects. The rate of metastasis and mortality from cutaneous squamous cell carcinoma were determined on a per-patient basis. Three of 28 patients with chronic lymphocytic leukemia had metastasis and died of metastatic disease. No metastases or deaths occurred among the 56 control subjects. Comparedwith control subjects, chronic lymphocytic leukemia patients with cutaneous squamous cell carcinoma were more likely to have metastasis (P = .0031) and die of metastasis (P = .0033). No significant association was detected between metastasis and history of chemotherapy administration for chronic lymphocytic leukemia. Among patients with chronic lymphocytic leukemia,
surveillance for skin cancer and a decreased threshold for biopsy of suspect lesions are warranted.
【总页数】2页(P12-13)
【作者】Mehrany; K.; Weenig; R.; H.; Lee; K.K.
【作者单位】不详; Department; of; Dermatology; Mayo; Clinic; 200; First; St; SW; Rochester; MN55905; United; States
【正文语种】中文
【中图分类】R739.5
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