参柏妇炎宁栓质量标准

参柏妇炎宁栓质量标准
冯颂桥;费毅琴
【期刊名称】《医药导报》
【年(卷),期】2015(34)12
【摘要】Objective To establish a method for quality control of Shenbo Fuyanning suppositories. Methods Sophorae flavescentis Radix, Rhizoma dioscoreae Hypoglaucae, and Cnidii fructus were identified by thin layer chromatography ( TLC) , and the content of berberine hydrochloride was determined by HPLC. Results The TLC spots were clear and the negative control had no interference.Berberine hydrochloride had a linear relationship in the range of 0.079-0.790 μg, and the average recovery was 99.3%(RSD=0.70%,n=6). Conclusion The method is accurate, reliable and feasible, and can be used in the quality control of the Shenbo Fuyanning suppository effectively.%目的建立参柏妇炎宁栓的质量标准. 方法采用薄层色谱法对制剂中苦参、粉萆薢、蛇床子进行定性鉴别;采用高效液相色谱法测定制剂中盐酸小檗碱含量. 结果薄层斑点清晰,阴性对照无干扰;盐酸小檗碱进样量在
0.079~0.790 μg范围内线性关系良好(r=0.999 9),平均回收率为99.3%,RSD值为0.70%(n=6). 结论该方法准确、可靠,可行及重复性良好,能有效控制参柏妇炎宁栓的质量.
【总页数】4页(P1649-1652)
【作者】冯颂桥;费毅琴
【作者单位】湖北省食品药品监督检验研究院,武汉 430064;湖北省食品药品监督检验研究院,武汉 430064
【正文语种】中文
【中图分类】R286;R927.2
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