康复新液联合奥美拉唑治疗慢性糜烂性胃炎的临床效果

反应总发生率比较袁差异无统计学意义渊P>0.05冤遥 结论 康复新液联合奥美拉唑治疗慢性糜烂性胃炎的效果显著袁
能有效减轻患者的炎症反应袁有效促使患者胃功能恢复袁值得临床推广应用遥
[关键词]慢性糜烂性胃炎曰康复新液曰奥美拉唑曰血清炎性因子曰幽门螺杆菌转阴率曰不良反应
[中图分类号] R573.3
[文献标识码] A
我院收治的 62 例慢性糜烂性胃炎住院患者作为研究对象袁按照随机数字表法分为对照组渊n=31冤和观察组渊n=
31冤遥 对照组给予奥美拉唑治疗袁观察组给予康复新液联合奥美拉唑治疗遥 两组均治疗 4 周后袁比较两组的治疗效
果尧治疗前后血清炎性因子水平尧胃功能相关指标及幽门螺杆菌转阴率尧用药后不良反应总发生率遥 结果 观察组
的治疗总有效率高于对照组袁差异有统计学意义渊P约0.05冤曰观察组治疗 4 周后的表皮生长因子尧白介素-6尧肿瘤
坏死因子-琢 水平均低于对照组袁差异有统计学意义渊P约0.05冤曰观察组治疗 4 周后0.05冤曰两组的幽门螺杆菌转阴率比较袁差异无统计学意义渊P>0.05冤曰两组的不良
中国当代医药 2019 年 12 月第 26 卷第 36 期
窑 临床研究 窑
康复新液联合奥美拉唑治疗慢性糜烂性胃炎的 临床效果
庞艳波 解放军北部战区总医院和平分院袁辽宁沈阳 110812
[摘要]目的 探讨康复新液联合奥美拉唑治疗慢性糜烂性胃炎的临床效果遥 方法 选取 2017 年 1 月~2018 年 9 月
[文章编号] 1674-4721渊2019冤12渊c冤-0079-04
Clinical effect of Kangfuxin Liquid combined with Omeprazole in the treatment of chronic erosive gastritis
PA NG Y an-bo Peace Branch of the General Hospital of the Northern Theater of the PLA, Liaoning Province, Shenyang 110812, China [Abstract] Objective To explore the clinical effect of Kangfuxin Liquid combined with Omeprazole in the treatment of chronic erosive gastritis. Methods A total of 62 patients with chronic erosive gastritis admitted to our hospital from January 2017 to September 2018 were selected as the study objects, they were divided into control group (n=31) and observation group (n=31) according to the random number table method. The control group was treated with Omepra鄄 zole, the observation group was treated with Kangfuxin Liquid combined with Omeprazole. After 4 weeks of treatment, the therapeutic effect, the level of serum inflammatory factors and the indexes related to gastric function before and af鄄 ter treatment, the negative rate of Helicobacterpylori and the total incidence of adverse reactions were compared be鄄 tween the two groups. Results The total effective rate of the observation group was higher than that of the control group, the difference was statistically significant (P<0.05). After 4 weeks of treatment, the levels of epidermal growth factor, interleukin-6 and tumor necrosis factor-琢 in the observation group were lower than those in the control group, the differences were statistically significant (P<0.05). The serum gastrin and motilin levels in the observation group af鄄 ter 4 weeks of treatment were higher than those in the control group, the differences were statistically significant (P< 0.05). There was no significant difference in the negative conversion rate of Helicobacterpylori between the two groups (P>0.05). There was no significant difference in the total incidence of adverse reactions between the two groups (P> 0.05). Conclusion Kangfuxin Liquid combined with Omeprazole is effective in the treatment of chronic erosive gastritis. It can effectively reduce the inflammatory response of patients and effectively promote the recovery of gastric function. It is worthy of clinical application. [Key words] Chronic erosive gastritis; Kangfuxin Liquid; Omeprazole; Serum inflammatory factor; Helicobacter pylori negative rate; Adverse reactions