阿尔茨海默症英语介绍
阿兹海默症英语作文
阿兹海默症英语作文Alzheimer's Disease: A Debilitating Condition and the Ongoing Pursuit of UnderstandingAlzheimer's disease is a devastating neurodegenerative disorder that affects millions of individuals worldwide. It is a progressive condition that gradually erodes an individual's cognitive abilities, memory, and overall quality of life. As the world's population continues to age, the prevalence of Alzheimer's disease is expected to rise, making it a pressing public health concern.At its core, Alzheimer's disease is characterized by the accumulation of specific proteins in the brain, leading to the destruction of neural connections and the death of brain cells. This gradual deterioration of brain function ultimately results in the loss of memory, language skills, problem-solving abilities, and other essential cognitive functions. Individuals with Alzheimer's disease often experience difficulty in performing everyday tasks, engaging in social interactions, and maintaining their independence.The impact of Alzheimer's disease extends beyond the individual affected. It also places a significant burden on families, caregivers,and the healthcare system as a whole. Caring for a loved one with Alzheimer's can be emotionally, physically, and financially taxing, as the disease progresses and the need for specialized care increases. The emotional toll on family members and caregivers can be immense, as they witness the gradual decline of their loved one and struggle to provide the necessary support.Despite the profound impact of Alzheimer's disease, the scientific community has made significant strides in understanding the underlying mechanisms of the condition. Extensive research has been conducted to unravel the complex interplay of genetic, environmental, and lifestyle factors that contribute to the development and progression of Alzheimer's disease. This research has led to advancements in early detection, diagnostic techniques, and the development of potential therapeutic interventions.One of the key areas of focus in Alzheimer's research is the identification of biomarkers – biological indicators that can help detect the disease in its early stages. By identifying these biomarkers, researchers aim to develop more accurate diagnostic tools that can facilitate earlier intervention and potentially slow the progression of the disease. Additionally, researchers are exploring various pharmacological and non-pharmacological approaches to manage the symptoms of Alzheimer's disease and improve the quality of life for those affected.Pharmacological interventions, such as the use of cholinesterase inhibitors and memantine, have been approved for the treatment of Alzheimer's disease. These medications aim to address the underlying neurochemical imbalances that contribute to the cognitive decline associated with the condition. While these treatments can provide temporary relief and potentially slow the progression of the disease, they do not offer a cure.Alongside pharmacological approaches, researchers are also investigating non-pharmacological interventions, such as cognitive stimulation therapy, physical exercise, and lifestyle modifications. These interventions focus on enhancing cognitive function, promoting brain plasticity, and addressing the overall well-being of individuals with Alzheimer's disease. By adopting a holistic approach to care, healthcare professionals and researchers aim to empower patients and their families to maintain the highest possible quality of life.Furthermore, the scientific community is actively engaged in exploring novel therapeutic strategies, including the development of disease-modifying drugs, immunotherapies, and stem cell-based therapies. These innovative approaches hold the potential to target the underlying pathological processes of Alzheimer's disease more effectively and potentially delay or even prevent the onset of thecondition.As the search for a cure continues, it is essential to recognize the importance of providing comprehensive care and support for individuals with Alzheimer's disease and their families. This includes the development of specialized care facilities, the implementation of caregiver support programs, and the promotion of public awareness and education about the disease.In conclusion, Alzheimer's disease is a complex and debilitating condition that poses significant challenges to individuals, families, and healthcare systems worldwide. However, the ongoing efforts of researchers, healthcare professionals, and the broader community have led to significant advancements in our understanding of the disease and the development of promising interventions. By continuing to invest in research, improving care and support systems, and fostering public awareness, we can strive to alleviate the burden of Alzheimer's disease and provide hope for those affected by this devastating condition.。
阿尔茨海默症英语介绍课件
More women than men 7:5~4:6
Disease for up to 10-20 years
PPT学习交流
9
Degradation of memory and cognition
PPT学W习交il流liam Utermohlen的自画像
10
Degradation of memory and cognition
PPT学习交流
11
Degradation of memory and cognition
• "the effects of Alzheimer's disease on the right parietal lobe of the brain are particularly severe, which directly affects the abilit of the brain to visualize and develop the ability to draw picture the brain."said Dr. Bruce Miller, a neurologist.
• His work became more abstract, may be the parietal function damaged, causing blindness.
• What kind of changes have occurred in the brains of patients w
03 Pathogeny＆Treatment
PPT学习交流
ቤተ መጻሕፍቲ ባይዱ
04 Other
3
1 brief introduction
PPT学习交流
阿尔茨海默症英语介绍演示PPT
➢ What kind of changes have occurred in the brains of patients with dementia, which is not yet fully understood by the world 's academia.
➢William insisted the 5 New Year paintings self portrait, until completely forgotten how to draw. From the use of skilled drawing, dark portrayal of vivid features, to the same color, shape deformation, self portrait became more and more abstract (pictured above).
Nerve cells die in areas of the brain that are vital to memory and other mental abilities.
7
2 Clinical manifestation
8
Clinical manifestation
Mild dementia Moderate dementia Severe dementia
临床症Clinical symptom
➢记忆障碍dysmnesia ➢失语aphasia ➢失认agnosia ➢执行功能障碍executive dysfunction ➢痴呆dementia
阿尔茨海默症英语介绍 ppt课件
Beta amyloid (blue curve) and Tau protein (orange curve) Research papers published in recent 30 years
Treatment
increase the concentration of acetylcholine (Ach) in the brain
9
Degradation of memory and cognition
William Utermohlen的自画像
Degtion
William Utermohlen is an American artist, in 1995 he was diagnosed with Alzheimer's disease. Since then, he has decided to take advantage of the limited time available to retain memory and better understand himself through self portraits.
Degradation of memory and cognition
"the effects of Alzheimer's disease on the right parietal lobe of the brain are particularly severe, which directly affects the ability of the brain to visualize and develop the ability to draw pictures of the brain."said Dr. Bruce Miller, a neurologist.
阿兹海默症英语作文
阿兹海默症英语作文Alzheimer's disease, named after German physician Alois Alzheimer, is a progressive neurodegenerative disorder that affects memory, thinking, and behavior. It is a silent thief, slowly robbing individuals of their cognitive abilities, often without any outward signs until the later stages. As the disease progresses, patients may experience difficulty with day-to-day activities, such as eating, bathing, and dressing, ultimately leading to a complete dependency on others for care.The prevalence of Alzheimer's disease is increasing worldwide, particularly in developed countries where the aging population is on the rise. This trend is expected to continue as life expectancies increase and more people live into their later years. The impact of Alzheimer's disease is not limited to the patients themselves; it also has a profound effect on their families and caregivers, who often face emotional, physical, and financial burdens.The symptoms of Alzheimer's disease vary from person to person, but some common signs include memory loss, confusion, language difficulties, mood changes, andimpaired judgment. As the disease progresses, these symptoms become more severe, and patients may experience delusions, hallucinations, and even loss of physical functions. There is currently no cure for Alzheimer's disease, and treatment options are limited to managing symptoms and improving quality of life.The cause of Alzheimer's disease is still not fully understood, but research suggests that it may be caused by a combination of genetic, environmental, and lifestyle factors. While genetics play a role in determining a person's risk of developing the disease, environmental factors such as diet, exercise, and social interaction may also influence its development. Therefore, preventing Alzheimer's disease is a complex task that requires a multifaceted approach.In terms of prevention, maintaining a healthy lifestyle is crucial. This includes eating a balanced diet, staying physically active, and engaging in social activities that stimulate the brain. Additionally, maintaining cognitive fitness through activities like reading, writing, andlearning new skills can help delay the onset of Alzheimer's disease.For those who are already affected by Alzheimer's disease, support and care are essential. This includes providing a safe and secure environment, assisting with daily activities, and offering emotional support. Caregivers should also seek respite care and support groups to help them cope with the stress and burden of caring for a person with Alzheimer's disease.In conclusion, Alzheimer's disease is a growing challenge in modern society. Its impact is felt not only by the patients themselves but also by their families and caregivers. By understanding the disease, its symptoms, and its causes, we can take steps to prevent its development and provide better support and care for those who are affected. While there is currently no cure for Alzheimer's disease, through research and innovation, we hope to find better ways to manage its symptoms and improve the quality of life for those who are living with it.**阿尔茨海默症：现代社会日益严峻的挑战**阿尔茨海默症，以德国医生阿洛伊斯·阿尔茨海默命名，是一种进行性神经退行性疾病，影响记忆、思维和行为。
阿尔茨海默症英语介绍
➢ 记忆障碍dysmnesia ➢ 失语aphasia ➢ 失认agnosia ➢ 执行功能障碍executive dysfunction ➢ 痴呆dementia
The disease usually begins after age 60, and risk goes up with age.
Two types
• Alzheimer's disease(AD) <65 years old
• senile dementia(SDAT) ≥65 years old
Name
In 1906,AD is named by Dr. Alois Alzheimer, a German doctor.
Memories of Tomorrow
The Notebook
Thank you
Degradation of memory and cognition
His work became more abstract, may be the parietal function damaged, causing blindness.
Thank you, my friends.
Clinical manifestation
alzheimersdiseaseadprogressiveneurodegenerativedisorder临床症状clinicalsymptom记忆障碍dysmnesia失语aphasia失认agnosia执行功能障碍executivedysfunction痴呆dementiadiseaseusuallybeginsafterage60riskgoesuptwotypes?alzheimersdiseasead65yearsold?seniledementiasdat65yearsolddraloisalzheimergermandoctor
阿兹海默症英语作文
阿兹海默症英语作文Title: Understanding Alzheimer's Disease.Alzheimer's disease is a progressive neurological disorder that affects the brain, leading to memory loss, cognitive decline, and changes in behavior. It is the most common form of dementia, affecting millions of people worldwide. As a caregiver, it is important to understand the challenges faced by individuals with Alzheimer's disease and provide them with the support and care they need.One of the key symptoms of Alzheimer's disease is memory loss, which can range from forgetting recent events to not recognizing close family members. This can be distressing for both the individual with Alzheimer's and their loved ones. As a caregiver, it is important to be patient and supportive, helping the person with Alzheimer's navigate their daily life with compassion and understanding.In addition to memory loss, individuals with Alzheimer's may also experience changes in behavior, such as confusion, agitation, and wandering. It is important to create a safe and supportive environment for them, ensuringthat they are not at risk of harm. Establishing routines and providing reassurance can help reduce anxiety and improve the quality of life for individuals with Alzheimer's.Furthermore, caregivers should encourage social interactions and engagement to help stimulate cognitive function and maintain a sense of connection with others. Activities such as music therapy, art therapy, and reminiscence therapy can be beneficial in improving mood and cognitive abilities in individuals with Alzheimer's.In conclusion, Alzheimer's disease presents unique challenges for both individuals with the condition and their caregivers. By understanding the symptoms and providing compassionate care and support, caregivers can help improve the quality of life for those affected by Alzheimer's disease.中文翻译：阿兹海默症。
阿尔兹海默症英语作文
阿尔兹海默症英语作文English:Alzheimer's disease is a progressive brain disorder that causes memory loss, cognitive decline, and behavioral changes. It is the most common cause of dementia among older adults, affecting millions of people worldwide. The exact cause of Alzheimer's is not yet fully understood, but it is believed to be a combination of genetic, environmental, and lifestyle factors. As the disease progresses, individuals may have difficulty completing daily tasks, communicating effectively, and recognizing loved ones. There is currently no cure for Alzheimer's, but early diagnosis and treatment can help manage symptoms and improve quality of life for those affected. Caregivers play a crucial role in supporting individuals with Alzheimer's, providing emotional support, assistance with daily activities, and ensuring a safe environment. Research into the causes and potential treatments for Alzheimer's is ongoing, offering hope for future breakthroughs in understanding and managing this challenging disease.中文翻译:阿尔茨海默病是一种渐进性的大脑障碍，导致记忆丧失、认知下降和行为变化。
认识阿尔茨海默病
认识阿尔茨海默病
September is Alzheimer’s Awareness Month
九月是阿尔茨海默病意识月
What is Alzheimer’s Disease?
什么是阿尔茨海默病？
Alzheimer’s Disease: 阿尔茨海默病
• Alzheimer’s is a type of dementia that affects memory, behavior and the thought process. It is the most common type of dementia that includes memory loss and other cognitive abilities that interfere with the activities of daily life.
• Changes in mood and personality.
情绪和性格的变化。
Is there anything I can
do to prevent
Alzheimer’s?
我能做些什么来预防阿尔茨海默病吗？
*** Please Note**
*** 请注意**
• At this time there is no known cure for Alzheimer’s Disease. 目前尚无
如果我认为自己有症状或我的亲人可能有症状，我该怎么办？去看 您的初级保健医生！
Thank you for your participation!
感谢您的参与！
Please let us know if you have any questions regarding the topic! 如果您对该主题有任何疑问，请告诉我们！
阿尔阿海默症英语作文
阿尔阿海默症英语作文Alzheimer's disease is a type of dementia that causesproblems with memory, thinking, and behavior. It is a progressive disease, where symptoms gradually worsen over a number of years, and it is the most common cause of dementia. This essay aims to provide an insight into the condition, its impact on individuals and their families, and the importanceof compassion and support.Firstly, it is crucial to understand the nature ofAlzheimer's disease. It is a neurodegenerative disorder that affects the brain, leading to a decline in cognitive function. The disease is characterized by the accumulation of amyloid-beta plaques and tau tangles, which are abnormal clusters of proteins that kill brain cells. As these proteins spread,they disrupt communication between brain cells and trigger inflammation, which damages the brain even further.The symptoms of Alzheimer's can be broadly categorized into three stages: mild, moderate, and severe. In the early stages, individuals may experience mild memory loss, difficulty in planning or solving problems, and changes in personality or behavior. As the disease progresses, symptoms become more pronounced, including confusion, short-term memory loss, and difficulty in recognizing family members. In the final stages, individuals lose the ability to communicate and care for themselves, and they may be bedridden.The impact of Alzheimer's disease extends beyond theindividual to their families and caregivers. Caring for a person with Alzheimer's can be emotionally, physically, and financially demanding. It requires a significant amount oftime and patience, and it can lead to feelings of isolation and depression among caregivers. It is essential for families to seek support from healthcare professionals, support groups, and community resources to manage the challenges of caregiving.There is currently no cure for Alzheimer's disease, but there are treatments available that can help manage symptoms andslow down the progression of the disease. Medications, suchas cholinesterase inhibitors and memantine, can improve cognitive function and daily functioning for some time. In addition, a healthy lifestyle that includes regular exercise, a balanced diet, and mental stimulation can help maintainbrain health and potentially reduce the risk of developing Alzheimer's.Lastly, society's approach to Alzheimer's disease should be one of empathy and understanding. It is important torecognize the dignity and worth of individuals living withthe disease and to provide them with a safe and supportive environment. This includes educating the public about the disease to reduce stigma, advocating for better resources and research, and promoting a culture of compassion and respectfor those affected by Alzheimer's.In conclusion, Alzheimer's disease is a complex andchallenging condition that affects millions of peopleworldwide. By understanding its nature, recognizing its impact on individuals and their families, and advocating for support and research, we can work towards a future where the burdens of Alzheimer's are lessened and where those living with the disease are treated with the kindness and respect they deserve.。
阿兹海默症英语作文
Alzheimer's Disease: A Silent InvasionAlzheimer's Disease, often referred to as AD, is a progressive neurodegenerative disorder that slowly robs individuals of their cognitive abilities, memory, and eventually, their autonomy. It's a silent invasion that creeps into the lives of sufferers and their loved ones, often without warning. As the fourth leading cause of death in the United States, AD affects millions worldwide, with new cases emerging every day.The symptoms of AD are diverse and can range from minor forgetfulness to severe cognitive decline. Early symptoms might include forgetfulness, difficulty in performing familiar tasks, confusion with time or place, and changesin mood or behavior. As the disease progresses, symptoms worsen, leading to problems with speaking, swallowing, and walking. Eventually, individuals with AD may require full-time care as they lose the ability to perform daily activities independently.The causes of AD are still not fully understood, but research suggests that genetic, environmental, andlifestyle factors may play a role. While there is currentlyno cure for AD, early diagnosis and treatment can help manage symptoms and improve the quality of life for both patients and their caregivers.The impact of AD on individuals and their families is profound. It can lead to feelings of isolation, helplessness, and guilt. Caregivers often face significant emotional and financial burdens as they strive to provide the best care possible for their loved ones. Support groups, counseling, and respite care can help ease these burdensand provide a sense of community for those affected by AD.As the global population ages, the number ofindividuals with AD is expected to rise. This makes it crucial for society to prioritize research and funding for AD. By investing in innovative research, we can hope tofind new treatments and even a cure for this devastating disease.In conclusion, Alzheimer's Disease is a complex and devastating condition that requires a multifaceted approach to address. It's essential for individuals, families, and society to work together to support those affected by AD,while also prioritizing research and awareness to findbetter treatments and a cure.**阿尔茨海默症：悄然的侵袭**阿尔茨海默症，常被称为AD，是一种渐进性的神经退行性疾病，它慢慢地剥夺了人们的认知能力、记忆，最终剥夺了他们的自主能力。
阿尔茨海默症英语介绍
.
12
3 Pathogeny＆Treatment
.
13
Pathogenesis hypothesis of AD
.
14
Pathogeny
vs
Abnormal amyloid beta cell deposition in neurons
Abnormal phosphorylation of tau protein
.
11
Degradation of memory and cognition
➢ "the effects of Alzheimer's disease on the right parietal lobe of the brain are particularly severe, which directly affects the ability of the brain to visualize and develop the ability to draw pictures of the brain."said Dr. Bruce Miller, a neurologist.
Ⅰ期
Ⅱ期
Ⅲ期
death
1-3 years 2-10 years 8-12 years
More women than men 7:5~4:6
Disease for up to 10-20 years
.
9
Degradation of memory and cognition
William Utermo.hlen的自画像
Nerve cells die in areas of the brain that are vital to memory and other mental abilities.
阿尔兹海默症英语作文
阿尔兹海默症英语作文Alzheimer's Disease: A Silent IntruderAs the sun sets on another day, the familiar sights and sounds of home become increasingly difficult to recognizefor those living with Alzheimer's Disease. This progressive neurodegenerative condition slowly erodes memory, thinking skills, and even the ability to perform daily tasks, often leaving sufferers and their loved ones feeling helpless and overwhelmed.The journey with Alzheimer's is not just about memory loss. It's about the emotional toll it takes on patientsand their caregivers, the constant struggle to maintain a sense of normalcy in a world that's constantly changing,and the heartbreaking reality of watching a loved oneslowly slip away.The first signs of Alzheimer's can be subtle and easily overlooked. Minor forgetfulness, such as misplacing keys or forgetting appointments, might be chalked up to old age or simple absentmindedness. However, as the disease progresses, symptoms become more severe and impactful. Languagedifficulties, confusion about time and place, and changesin mood and behavior become more pronounced.For caregivers, the challenge lies in navigating these changes while maintaining a sense of compassion and understanding. It's about finding the balance between providing enough support and allowing the patient to retain some sense of independence. It's about understanding that while the world might be collapsing around them, thepatient is still the same person they've always been, trapped inside a body that's slowly failing them.The emotional toll on caregivers can be immense. They might feel a sense of helplessness as they watch their loved one struggle with daily tasks that have become increasingly difficult. They might feel guilt for not being able to do more, or anger towards the disease that's stealing their loved one's memory and identity.However, it's important to remember that while Alzheimer's is a challenging disease, it's not impossible to cope with. There are support groups, therapies, and medications that can help manage symptoms and improve quality of life. Caregivers must also take care ofthemselves, finding time for self-care and seeking support when needed.In the end, the journey with Alzheimer's is about more than just memory loss. It's about finding meaning and purpose in each day, about cherishing the moments thatstill bring joy and happiness, and about holding onto hope that one day, we will find a way to stop this relentless disease from stealing our loved ones' futures.阿尔兹海默症的艰难之旅阿尔兹海默症：悄然而至的入侵者随着太阳落山，家中的熟悉景象和声音对于患有阿尔兹海默症的人来说变得越来越难以辨认。
阿兹海默症英语作文
The Challenges of Alzheimer's Disease: AGlobal PerspectiveAlzheimer's Disease (AD) is a progressive neurodegenerative disorder that slowly destroys memory, thinking skills, and the ability to perform daily activities. It is named after Alois Alzheimer, the German doctor who first described the condition in 1906. Today, it stands as one of the most significant health challenges facing society, particularly given its increasing incidence among the elderly population.The impact of AD is profound, not only on the individuals affected but also on their families and caregivers. As the disease progresses, it can lead to changes in personality, mood, and behavior, often resulting in a decline in quality of life for both the patient and their caregivers. Furthermore, the economic burden of AD is immense, with costs related to healthcare, long-term care, and lost productivity exceeding trillions of dollars worldwide.The pathogenesis of AD is complex and not fully understood. However, research has identified severalfactors that contribute to its development, including genetic predisposition, age, and lifestyle factors such as diet and exercise. Currently, there is no cure for AD, but various treatments are available to manage symptoms and improve quality of life.One of the most significant challenges in addressing AD is the lack of awareness and understanding among the general population. Many people are unaware of the signs and symptoms of AD, leading to delayed diagnosis and intervention. Therefore, it is crucial to increase public awareness and education about AD to facilitate early detection and timely management.Another challenge is the limited availability of effective treatments for AD. While some medications can temporarily improve symptoms, they cannot halt the progression of the disease. This underscores the need for continued research and development of new therapies that can target the underlying causes of AD.In conclusion, Alzheimer's Disease is a devastating condition that poses significant challenges to individuals, families, and society. It requires a comprehensive approachthat involves increased public awareness, early detection, effective management, and ongoing research. Only through collective effort and dedication can we hope to overcomethis global health crisis.**阿尔茨海默症：全球视角下的挑战**阿尔茨海默症（AD）是一种渐进性的神经退行性疾病，它会慢慢破坏人的记忆、思考能力和日常生活能力。
阿尔茨海默病 老年痴呆 Alzheimer’s Disease 英语作文
Alzheimer’s Disease Alzheimer’s Disease Essay:Alzheimer’s disease is a degenerative disorder which slowly leads to memory loss in a person. It damages the brain tissues and is a form of dementia. It ultimately damages the human brain.It occurs in the later years of life and is seen in middle-aged and older people at the late 65s. There is no such cure to this disease, but medication often helps to improve the condition.Long and Short Essays on Alzheimer’s Disease for Students and Kids in EnglishWe are providing students with essay samples on a long essay of 500 words and a short essay of 150 words on the topic Alzheimer’s Disease for reference.Long Essay on Alzheimer’s Disease 500 Words in EnglishLong Essay on Alzheimer’s Disease is usually given to classes 7, 8, 9, and 10.A German neurologist named Alois Alzheimer discovered Alzheimer’s disease in 1906 after studying the case of a middle-aged woman named Auguste D. After her death he found senile plaques and neurofibrillary tangles as he did an autopsy. Alzheimer’s disease or AD is a form of dementia which leads to the loss of a person’s ability to think and reason. It destroys the memory as neurons are injured and die throughout the brain resulting in a break down in the connections between networks of neurons. Major brain regions begin to shrink. By the final stages of Alzheimer’s significant loss of brain volume is seen, which is called brain atrophy.The most crucial symptom of Alzheimer’s is memory loss, and the person faces difficulties in remembering. It also leads to occasional memory lapses. An Alzheimer’s patient often gets lost in familiar places and also does not find the right word to identify objects and often tends to forget close relatives and family members.Alz heimer’s reduce the ability of thinking and reasoning considerably, and the person fails to make decisions or proper judgements. As the disease progresses, the patient often forgets to perform familiar tasks or even the basic tasks like bathing or dressing. An Alzheimer’s patientundergoes many behavioural and personality changes like depression, delusion and mood swings are prevalent. Distrust, social withdrawal, changes in sleeping patterns and aggressiveness also occur.Alzheimer’s is caused by a combin ation of genetics, lifestyle and environmental factors over time though the exact reason causing Alzheimer’s is yet to be found. The problems with brain proteins disrupt the proper functioning of the brain cells and eventually die out, resulting in a loss of significant portions of the brain.The human brain is characterised by amyloid plaques and neurofibrillary tangles caused by significant brain degeneration due to Alzheimer’s.A leftover fragment of a larger protein called beta-amyloid, and its clustering have a toxic effect on neurons, and it disrupts the cell-to-cell communication. Neurofibrillary tangles are abnormal accumulations of a protein called tau that collects inside neurons. Apart from these, chronic inflammations, vascular problems and cell death re major characteristics of Alzheimer’s.The early symptoms include mild forgetfulness, anxiety, confusion about time and place,communication difficulties and loss of spontaneity and initiative. Toward the progress of this disease, short term memory loss and confusion increase with a shorter span of attention and severe forgetfulness and even recognising family members. In the last stage, the inability to understand, incontinency and failure to recognise self or family are common.Researches show that 60-90% of Alzheimer’s cases exhibit various cerebrovascular pathology. Strokes are prevalent in patients with Alzheimer’s syndrome and worsen the cognitive decline substantially with various internal andexternal disorders. The risk factors include increasing age, genetics and down syndrome specifically. Obesity, high blood pressure and cholesterol, history of a previous head injury, blood vessel disease, etc. are also considered.A thorough diagnosis of an Alzheimer’s patient is made by assessing the assessing a person’s medical and psychiatric history and brain scans. CT, MRI and PET scans are done to determine the level of mental deterioration. Apart from these, blood and urine tests are also done along with proper neurological and physical examinations.Short Essay on Alzheimer’s Disease 150 Words in EnglishShort Essay on Alzheimer’s Disease is usually given to classes 1, 2, 3, 4, 5, and 6.Alois Alzheimer first found the symptoms of Alzheimer’s Disease (AD) after studying the case of a 51 years old woman. He found out destructions in brain cells and rapid degeneration of the brain. AD tends to damage the human brain entirely with significant memory loss and an inability to recognise self and close family members. AD is also associated withaggressiveness, restlessness, mental trauma, insomnia and severe depression.Beta-amyloid plaques and neurofibrillary tangles in the brain are significant causes for brain damage and subsequent loss of memory.A build-up of glial cells, vascular issues like atherosclerosis and considerable damage in the brain cells are equally responsible for AD. Although a person undergoes all types of brain scans, there is no cure for AD or any proven way for prevention. Treatments improve the behavioural patterns and manage symptoms to maximise a person’s ability to carry out dailyactivities and tasks so that they maintain their independence for as long as possible.10 Lines on Alzheimer’s Disease in EnglishAlzheimer’s disease gradually leads to loss of memory.A person diagnosed with AD experiences an inability of thinking, recognising and making judgements.AD damages the brain cells and tissues resulting in loss of an essential portion of the brain.Brain damage is associated with the build-up of abnormal proteins that form “plaques” and “tangles” around the brain cells.Family members face difficulties as the person’s condition deteriorates and are unable to recognise loved ones.Medications help to control sleeplessness, agitation, aggression and depression.There is no prevention of AD, but reports suggest a healthy lifestyle might reduce the risk.Regular physical activities have a protective effect on brain health and reduce the progression of AD.In AD, the loss of neurons spreads predictably, and brain size shrinks significantly.Risk factors include genetics, down syndrome, post head trauma, heart and vascular diseases, etc.FAQ’s on Alzheimer’s Disease EssayQuestion 1.What are the causes of AD?Answer:The exact causes of AD are not known, but problems with brain proteins that fail to function normally, disrupt the work of neurons and results in a series of toxic events.Question 2.How to prevent AD?Answer:There is no prevention to AD, but proper lifestyle might reduce the risk.Question 3.What are medicines used in cases of AD?Answer:Mostly, anti-depressants and sleeping pills are used to improve the sleep pattern because this disease cannot be cured.。
Alzheimers阿兹海默症介绍(英汉)
阿兹海默症Alzheimer’s DiseaseAlzheimer’s Disease is the most common type of dementia. Dementia occurs as a result of changes in the brain that affect a person’s ability to think and remember. It can become severe enough to affect daily activities.Alzheimer’s Disease causes brain changes over years and is not a normal part of aging. No one knows what causes Alzheimer’s Disease, but much research is being done. You may be more at risk if you had a family member with the disease.SignsThe signs start slowly and can vary or worsen over time. A person cannot control the signs. Treatment can help, but it does not cure the disease.Signs may include:•Memory loss, especially about recent events•Confusion about time and place•Poor judgment•Trouble learning new information •Changes in being able to do such things as drive, handle money, take medicine,cook, dress and bathe•Loss of sense of smell•Wandering or getting lost 阿兹海默症是最常见的痴呆类型。
阿尔兹海默症英语作文
阿尔兹海默症英语作文Alzheimer's Disease: A Debilitating Condition Affecting MillionsAlzheimer's disease is a devastating neurodegenerative disorder that primarily affects the elderly population. It is a progressive condition that gradually erodes an individual's cognitive abilities, memory, and overall quality of life. As the global population continues to age, the prevalence of Alzheimer's disease has been steadily increasing, making it a significant public health concern.The onset of Alzheimer's disease is often insidious, with early symptoms such as forgetfulness and difficulty in recalling recent events. As the disease progresses, patients experience more severe cognitive impairments, including trouble with language, decision-making, and even basic daily tasks. The deterioration of memory and cognitive functions can have a profound impact on the individual's independence, emotional well-being, and relationships with loved ones.One of the hallmarks of Alzheimer's disease is the accumulation of abnormal proteins, such as amyloid-beta and tau, in the brain. These proteins form plaques and tangles that disrupt the normalfunctioning of brain cells, leading to their eventual death. This neurodegeneration primarily affects the areas of the brain responsible for memory, learning, and cognitive processing, resulting in the characteristic symptoms of Alzheimer's disease.The exact causes of Alzheimer's disease are not fully understood, but a combination of genetic, environmental, and lifestyle factors are believed to play a role. Certain genetic mutations have been identified as risk factors, and individuals with a family history of the disease are at a higher risk of developing it. Additionally, factors such as age, cardiovascular health, and cognitive activity throughout life have been linked to the development and progression of Alzheimer's disease.The impact of Alzheimer's disease extends far beyond the individual patient. Caregiving for individuals with Alzheimer's can be physically, emotionally, and financially taxing for family members and loved ones. The progressive nature of the disease often requires extensive support and assistance with daily activities, which can strain the resources and well-being of caregivers.Furthermore, the societal burden of Alzheimer's disease is significant. The healthcare costs associated with the management and care of Alzheimer's patients are substantial, placing a significant strain on healthcare systems and economies around the world. Additionally,the loss of productivity and the emotional toll on families and communities can have far-reaching consequences.Despite the challenges posed by Alzheimer's disease, there is ongoing research and development in the field of Alzheimer's research. Scientists and medical professionals are working tirelessly to better understand the underlying mechanisms of the disease, with the ultimate goal of developing more effective treatments and preventive strategies.Current treatments for Alzheimer's disease primarily focus on managing the symptoms and slowing the progression of the disease. Medications such as cholinesterase inhibitors and memantine can temporarily improve cognitive function and delay the worsening of symptoms. However, these treatments are not curative, and their effectiveness diminishes as the disease progresses.Alongside pharmacological interventions, non-pharmacological approaches, such as cognitive stimulation, physical activity, and social engagement, have also been explored as ways to improve the quality of life for individuals with Alzheimer's disease. These interventions aim to maintain cognitive function, promote overall well-being, and provide support for both patients and their caregivers.As the global population continues to age, the prevalence of Alzheimer's disease is expected to rise significantly in the coming decades. This looming public health challenge underscores the urgent need for continued research, improved diagnostic tools, and the development of more effective treatments. By working collaboratively, the scientific community, healthcare providers, policymakers, and the general public can strive to address the multifaceted challenges posed by Alzheimer's disease and improve the lives of those affected by this devastating condition.。
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Clinical manifestation
Clinical manifestation
Mild dementia Moderate dementia Severe dementia
Ⅰ期
1-3 years
Ⅱ期
Ⅲ期
death
2-10 years
7:5~4:6
8-12 years
More women than men
3
Pathogeny＆othesis of AD
Pathogeny
vs
Abnormal amyloid beta cell deposition in neurons Abnormal phosphorylation of tau protein
His work became more abstract, may be the parietal function damaged, causing blindness. What kind of changes have occurred in the brains of patients with dementia, which is not yet fully understood by the world 's academia.
临床症状Clinical symptom 记忆障碍dysmnesia 失语aphasia 失认agnosia 执行功能障碍executive dysfunction 痴呆dementia
The disease usually begins after age 60, and risk goes up with age.
Catalog
01
brief introduction
02
Clinical manifestation
03
Pathogeny ＆ Treatment
04
Other
1
brief introduction
What?
Alzheimer's disease (AD) is a progressive neurodegenerative disorder .
Two types
• Alzheimer's disease(AD) <65 years old • senile dementia(SDAT) ≥65 years old
Name
In 1906,AD is named by Dr. Alois Alzheimer, a German doctor. Dr. Alzheimer noticed changes in the brain tissue of a woman who had died of an unusual mental illness. He found abnormal clumps. Scientists also have found other brain changes in people with AD. Nerve cells die in areas of the brain that are vital to memory and other mental abilities.
4
Other
Film
Still Alice
The film tells the story of Alice Howland in seriously AD but still strong and brave .
The film won the eightyseventh Oscar award
William insisted the 5 New Year paintings self portrait, until completely forgotten how to draw. From the use of skilled drawing, dark portrayal of vivid features, to the same color, shape deformation, self portrait became more and more abstract (pictured above).
Degradation of memory and cognition
"the effects of Alzheimer's disease on the right parietal lobe of the brain are particularly severe, which directly affects the ability of the brain to visualize and develop the ability to draw pictures of the brain."said Dr. Bruce Miller, a neurologist.
promoting survival of cholinergic neurons in the brain or improving their nerve conduction function
reducing the production or promoting degradation of beta amyloid
Memories of Tomorrow
The Notebook
Thank you
Disease for up to 10-20 years
Degradation of memory and cognition
William Utermohlen的自画像
Degradation of memory and cognition
William Utermohlen is an American artist, in 1995 he was diagnosed with Alzheimer's disease. Since then, he has decided to take advantage of the limited time available to retain memory and better understand himself through self portraits.
Alzheimer ’s Disease
阿尔茨海默症
Ronald Wilson Reagan 罗纳德·威尔逊·里根
第40任（第49-50届）美国总统 president “I know I'm on my way to the twilight. I know there's always a bright dawn ahead of the United states. Thank you, my friends. May God bless you forever.”
Beta amyloid (blue curve) and Tau protein (orange curve) Research papers published in recent 30 years
Treatment
increase the concentration of acetylcholine (Ach) in the brain