阿尔茨海默症英语介绍课件

More women than men 7:5~4:6
Disease for up to 10-20 years
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Degradation of memory and cognition
PPT学W习交il流liam Utermohlen的自画像
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Degradation of memory and cognition
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Degradation of memory and cognition
• "the effects of Alzheimer's disease on the right parietal lobe of the brain are particularly severe, which directly affects the abilit of the brain to visualize and develop the ability to draw picture the brain."said Dr. Bruce Miller, a neurologist.
• His work became more abstract, may be the parietal function damaged, causing blindness.
• What kind of changes have occurred in the brains of patients w
03 Pathogeny＆Treatment
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ቤተ መጻሕፍቲ ባይዱ
04 Other
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1 brief introduction
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What?
Alzheimer's disease (AD) is a progressive neurodegenerative disorder .
临床症状Clinical symptom
He found abnormal clumps. Scientists also have found other brain changes in people with AD.
Nerve cells die in areas of the brain that are vital to memory and other mental abilities.
•William insisted the 5 New Year paintings self portrait, until completely forgotten how to draw. From the use of skilled drawi dark portrayal of vivid features, to the same color, shape deformation, self portrait became more and more abstract (pictured above).
Alzheimer’s Disease
阿尔茨海默症
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Ronald Wilson Reagan 罗纳德·威尔逊·里根
第40任（第49-50届）美国总统 president
“I know I'm on my way to the twilight. I know there's always a
dementia, which is not yet fully understood by the world 's
academia.
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3 Pathogeny＆Treatment
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Pathogenesis hypothesis of AD
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Pathogeny
bright dawn ahead of the United states. Thank you, my friends.
May God bless you forever.”
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Catalog
01 brief introduction
02 Clinical manifestation
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Name
In 1906,AD is named by Dr. Alois Alzheimer, a German doctor.
Dr. Alzheimer noticed changes in the brain tissue of a woman who had died of an unusual mental illness.
•记忆障碍dysmnesia
•失语aphasia
•失认agnosia
•执行功能障碍executive dysfunction
•痴呆dementia
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Two types
•Alzheimer's disease(AD) <65 years old
•senile dementia(SDAT) ≥65 years old
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2 Clinical manifestation
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Clinical manifestation
Mild dementia Moderate dementia Severe dementia
Ⅰ期
Ⅱ期
Ⅲ期
death
1-3 years 2-10 years 8-12 years
•William Utermohlen is an American artist, in 1995 he was diagnosed with Alzheimer's disease. Since then, he has decided t take advantage of the limited time available to retain memory an better understand himself through self portraits.
vs
Abnormal amyloid beta cell deposition in neurons
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Abnormal phosphorylation tau protein