血清PCT和hs-CRP在新生儿全身炎症反应综合征的应用价值

血清PCT和hs-CRP在新生儿全身炎症反应综合征的应用价
值
王明霞;徐洪安;刘建平
【期刊名称】《四川医学》
【年(卷),期】2015(000)007
【摘要】目的：探讨血清降钙素原( PCT)和超敏C反应蛋白( hs-CRP)在新生儿全身炎症反应综合征( SIRS)的临床价值。

方法68例SIRS新生儿,其中细菌感染组
42例和非细菌感染组26例,按新生儿危重病例评分法评分分为非危重组、危重组、极危重组,检测治疗前后血清PCT、hs-CRP水平并进行分析。

结果 SIRS新生儿血清PCT、hs-CRP水平均高于对照组,细菌感染组PCT水平与非细菌感染组比较差
异有统计学意义( P<0．01),而两组间hs-CRP差异无统计学意义( P>0．05),经过有效治疗后,SIRS患儿的PCT、hs-CRP水平均明显下降,危重程度越高其PCT值越高。

结论PCT有助于识别感染性和非感染性SIRS,动态监测PCT,对判断感染程度、疾病预后和疗效均有帮助,是细菌感染性疾病理想的生物指标。

%Objective To investigate the application value of serum PCT, hs-CRP levels and in the systemic inflammatory response syndrome( SIRS) with Newborns. Methods 68 neonates with SIRS were chosed to investigated, SIRS groups were
divid-ed into bacterial infection group(42cases)and the non-bacterial infection group(26cases), and grading by neonatal critical illness score, these neonates also divided into non critical group, critical group, extremely critical group, the levels of serum PCT, hs-CRP in those neonates were measured before and after treatment. Results The levels of serum
PCT, hs-CRP levels in all neo-nates with SIRS are higher than those in the control group, but compared with non-bacterial infection group, the PCT level were significant difference(P< 0. 01)in bacterial infection group, while the hs-CRP level shoned no difference between the two groups (P>0. 05), after effective treatment, both PCT and hs-CRP level were significantly decreased in all children with SIRS, and the level of PCT but not hs-CRP was related to the critical degree. Conclusion PCT coulde be used as an indicator to identify infec-tious and non-infectious SIRS,and dynamic monitoring the level of PCT help to determine the extent of infection, disease prognosis and treatment efficacy, which is an ideal biological indicators of bacterial infections.
【总页数】3页(P1017-1019)
【作者】王明霞;徐洪安;刘建平
【作者单位】乐山市市中区妇幼保健院儿科，四川乐山614000;乐山市市中区妇幼保健院儿科，四川乐山614000;乐山市市中区妇幼保健院儿科，四川乐山614000
【正文语种】中文
【中图分类】R722.1
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