le01(2010)

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SPS工艺对铜_金刚石复合材料性能的影响

SPS工艺对铜_金刚石复合材料性能的影响

万方数据张毓隽等:SPS工艺对铜,金刚石复合材料性能的影响28No。

.1n冲电流通过粉末颗粒时瞬间产生的放电等离子体,使烧结体内部各个颗粒均匀地自身产生焦耳热,并使颗粒表面活化进而烧结成形的一种方法。

这种放电直接加热法热效率极高,放电点的弥散分布能够实现均匀加热,因而容易制备出均质、致密和高质量的烧结体18母】。

国内外已经有不少研究者将其应用在制备复合材料上【l啪ll】,并取得了很好的效果。

由于铜/金刚石材料是一种新型的复合材料,国内外对其研究还处于起步阶段,而且现在大多数的国外制备工艺都是高温高压法或是熔渗法,而国内的北京科技大学和有色院等【I2l单位刚刚开始对其进行了探索性研究,对于SPS制备铜/金刚石材料来说,还没有一条成熟的工艺。

笔者利用烧结温度、保温时间和烧结压强这三个SPS中主要的工艺参数对复合材料相对密度和热导率的影响,来优化其烧结工艺,制备出热导率和相对密度均较高的铜/金刚石复合材料。

1实验所用原材料为:市售MBD8镀钛金刚石(钛与金刚石质量比为hl000),粒度100“m,市售纯度为99.6%的铜粉,粒度约为20I.tm。

图1为镀钛金刚石粉末表面的SEM照片。

陶1镀铁盒川白的SEM照片Fig.1SEMmicrographofthetitaniumcoateddiamond实验方法为:将金刚石和铜的粉末按体积分数60%混合均匀,送入SPS烧结炉(日本住友DrSinter@SPS—1050)中进行烧结,真空度为4—5Pa,升温速度为1.5℃·s_1,通过改变烧结温度、保温时间和压强等参数来考察复合材料相对密度和热导率的变化。

得到的样品采用排水法测其密度,用LE01450型扫描电镜(SEM)进行组织观察。

采用激光闪烁法(仪器趔号为耐驰LFA427)测定该复合材料的热传导系数,按公式(1)计算热导率A:/t=DrC(1)式中:D为实验测得的热传导系数:r为复合材料的密度,可由排水法测得;C为该复合材料的热容,可按混合法则公式(2)得到:cc=CcuVcu+Ct)iaVoia(2)式中:Cc,cC。

HFUT_272ba32842

HFUT_272ba32842

院(部)教师课程代码课程名称教学班号仪器程真英01000120仪器与系统可靠性0001仪器吕国强,洪占勇01000170智能化测控系统0001仪器吴晔01000280现场总线技术及应用0001仪器陶晓杰,雷丽巧,张腾达01000440机光电综合课程设计00010001仪器李红莉01000660可编程控制器(光信息)仪器刘芳芳01000700测控电路(测控)0001仪器张勇01000710测控仪器设计(测控)00010001仪器党学明01000730控制技术与系统(测控技仪器杨永跃01000780视觉检测技术0001仪器彭良清,洪占勇,吴晔01000800仪器及系统课程设计0001仪器张腾达01000860数字信号分析与处理0001仪器刘晨01000920光电检测技术(Ⅱ)00010001仪器胡毅01000940虚拟技术与仪器(光信息仪器金施群01000950数字图象处理0001仪器杨永跃01001030机器视觉技术0001仪器高大军01001080光纤技术及应用0001仪器杨永跃,金施群,郎贤礼01001110机器视觉系统设计0001仪器于连栋01001150数字信号处理(测控技)0001仪器张阳01002090嵌入式系统及应用0001仪器陈晓怀01000010误差理论与数据处理0001仪器王永红01000020传感技术0001仪器李勇101000020传感技术0002仪器张辉,张阳01000040微机原理与应用0001仪器张辉,张阳01000110微机接口技术0001仪器胡毅,张阳,李红莉01000370微机接口实践0001仪器张勇,刘善林,黄斌01000380精密机械课程设计0001仪器刘晨01000640工程光学0001仪器雷丽巧01000830波动光学00010001仪器黄强先01000930误差理论与数据处理(光仪器高大军01000970检测与转换技术(Ⅱ)0001仪器刘志健,王永红,程真英01001100光学课程设计0001仪器王永红,冯奇斌,刘芳芳01001140传感器实践0001仪器陶晓杰,黄斌04002100精密机械设计(Ⅱ)00010001仪器刘善林01000670机械设计基础(光信息)0001仪器邓善熙,杨世元,费业泰01002070测控技术与仪器专业导0001仪器陈晓怀,胡鹏浩,费业泰01002080光信息科学与技术专业仪器杨蕾01200320数学物理方法00010001仪器费业泰,余晓芬,邓善熙01002010测控技术与仪器专业导0001仪器吕国强,张辉,费业泰01002020光信息科学与技术专业机械祝安定02000480液压传动与控制0001机械朱武,褚向前02000490微机接口与控制0001机械董迎晖02000520有限元分析0001机械尹志强,王玉琳02000550机电一体化系统设计0001机械桂贵生02000590自动化制造系统0001机械梁平02000610现代制造系统0001机械翟华,于道洋02000790可靠性设计0001机械韦艳丽02000810工业造型设计0001机械刘志峰,黄海鸿02000880绿色设计与绿色制造0001机械王健强02000890机器人学0001机械王淑旺02000890机器人学0002机械朱仁胜02000900制冷与低温技术0001机械干蜀毅02000910超高真空设备及技术0001机械钱叶剑02001030排污净化0001机械左承基02001050内燃机增压技术0001机械滕勤02001060内燃机电控技术0001机械谭继锦02001070有限元法在动力机械中0001机械刘一鸣02001090优化设计0001机械程晓章02001100内燃机可靠性设计00010001机械程晓章02001120内燃机故障分析与排除机械钱叶剑02001140内燃机试验学0001机械吴昊02001160吸收式制冷机0001机械叶斌02001180热泵0001机械王铁军02001190制冷装置自动化00010001机械刘向农02001200流体机械(离心压缩机.机械刘向农02001210低温制冷机0001机械叶斌02001220制冷工质替代0001机械江斌02001230制冷热动力学0001机械魏道高02001350特种运输车辆0001机械黄文娟,张卫华02001480交通流理论0001机械周蓉,葛茂根02001540物流工程0001机械沈维蕾02001550质量管理与可靠性0001机械毕宝庆02001660项目管理0001机械朱武02001730过程控制及仪表0001机械唐志国02001750制冷原理与低温技术0001机械唐志国02001810过程节能原理及应用0001机械王庆生02001820过程装备CAD00010001机械魏道高02001910人机工程学与车身造型机械尹安东,孙骏02001940车辆试验学0001机械张代胜02001950车辆诊断0001机械王伟1,尤涛02002020摩擦学0001机械韦艳丽,祝莹02002140设计专题(Ⅰ)0001机械束晓永,张宝02002140设计专题(Ⅰ)0002机械朱政红02002380制造装备课程设计0002机械干蜀毅02002380制造装备课程设计0003机械朱政红02002570CAD实习0001机械韩春明02002600工业设计综合实践0001机械朱武02002660综合实验(分散)0001机械唐景春02002660综合实验(分散)0002机械刘勇强02002660综合实验(分散)0003机械温千宏02002730生产实习(交通)00010001机械曹国安02002770设施规划与物流分析课机械沈健02002830过程装备课程设计0001机械沈健02002840过程装备综合实验0001机械徐建忠02002910车辆理论试验0001机械高荣慧,黄康02002970机械系统设计00010001机械王玉琳02003000单片机原理及应用(机设0002机械褚向前,朱武02003000单片机原理及应用(机设0001机械丁苏赤02003010计算机控制技术(机设)机械张雷02003020计算机网络技术(Ⅱ)0001机械王君02003110专业英语0001机械叶斌02003110专业英语0002机械钱叶剑02003110专业英语0004机械唐景春02003150空气调节0001机械刘一鸣02003610内燃机设计(热能)0001机械唐景春02003680食品冷冻冷藏技术0001机械刘向农02003690暖通工程0001机械叶斌02003700制冷装置0001机械朱武02003830过程控制课程设计0001机械江晓淮02003890液压传动与控制(Ⅱ)0001机械夏永胜02003920现代集成制造系统0001机械谢峰02003950先进制造技术00010001机械尹志强02003970电力电子学与伺服电机机械张崇高02003980精密与特种加工0001机械胡小春02003990PRO/E0001机械曹文钢02003990PRO/E0002机械柴畅02004000模具设计0001机械王健强02004010面向对象程序设计0001机械曹国安02004020工业工程(Ⅱ)0001机械王君,方应翠02004030表面改性技术与设备0001机械朱武02004040真空仪器与设备电路0001机械黄海鸿,刘志峰02004050计算机系统仿真0001机械尹志强02004060机械电子工程综合课程00010001机械朱武02004080真空设备自控课程设计机械魏道高,张炳力02004110车辆设计总论0001机械刘俊02004120车辆可靠性设计0001机械张卫华,方锡邦02004220交通事故工程(Ⅱ)0001机械丁恒,姜康02004230交通控制与管理(Ⅱ)0001机械黄文娟,张卫华02004240智能运输系统(Ⅱ)00010001机械李智超02004260汽车运输企业设计(交通机械徐娟02004270汽车保险与理赔0001机械丁恒,谭继锦02004330交通工程设计理论0001机械殷晓晨02004440专业英语(工业设计)0001机械韦艳丽,祝莹02004540多媒体设计0001机械韩春明02004600专业设计实习0001机械曹国安02004690生产计划与控制(Ⅱ)0001机械扈静02004700管理信息系统(Ⅱ)0001机械沈维蕾02004760企业资源计划00010001机械曹国安,蒋增强02004770精益生产方式--准时化机械王跃飞02004830现代软件技术基础00010001机械张建军,尹涓02004870可编程序控制器原理及机械王君02004890真空技术综合实验0001机械阳巧02004990展示设计(工业设)0001机械阳巧02004990展示设计(工业设)0002机械祝莹,韦艳丽02005000包装设计(工业设)00010001机械曹国安02005020管理信息系统课程设计机械高荣慧02005140机械创新设计00010001机械高荣慧02005170机械产品综合课程设计机械杨海东,吴仲伟02005200机械电气与PLC控制0001机械吕坤02005370MDT造型(公选)00010001机械张晔02005450快速原型及快速模具制0001机械王铁军02005460制冷技术及应用(公选)机械吕坤02005570计算机绘图(公选)0001机械董玉德02005690CAD开发技术0001机械张崇高,杨海东02005700现代刀具设计与制造0001机械肖东02000010流体力学(Ⅳ)0001机械蔡二南02000040流体力学(Ⅱ)0001机械揭德祘02000040流体力学(Ⅱ)0002机械夏永胜,曾亿山02000040流体力学(Ⅱ)0003机械曾亿山,夏永胜02000040流体力学(Ⅱ)0004机械于振华02000040流体力学(Ⅱ)0005机械张崇高,唐火红02000050制造技术基础0001机械张学斌02000060机械工程材料0001机械程晓章02000080发动机0001机械卢剑伟02000090汽车学0001机械姜平02000100系统工程学(交通工)0001机械谭继锦,郑小燕02000120道路工程总论0001机械李智超,张代胜02000130交通运输学0001机械王跃飞02000230计算机网络技术0001机械张彦如02000250机械制造技术0001机械张萍02000260人机工程学0001机械毕宝庆02000280工程经济0001机械祝安定02000300车辆液压与液力传动0001机械陈苏欣02000310控制工程基础0001机械孙骏,祝安定02000310控制工程基础0002机械任永强02000310控制工程基础0003机械刘征宇02000310控制工程基础0004机械曹文钢02000310控制工程基础0005机械殷晓晨02000410模型制作基础0001机械丁曙光02000470测试技术0001机械丁曙光02000470测试技术0002机械赵小勇02000470测试技术0003机械赵小勇02000470测试技术0004机械夏永胜,曾亿山02000480液压传动与控制0002机械曾亿山,夏永胜02000480液压传动与控制0003机械蔡二南02000480液压传动与控制0004机械石琴02001520专业英语(交通工)0001机械朱仁胜,沈健02001700过程流体机械0001机械沈健,张烨02001710过程装备设计基础0001机械姜武华,卢剑伟02001830车辆构造0001机械卢剑伟,石琴02001990专业英语1(车辆)0001机械刘学02002050工业设计史0001机械栗洪宁02002080摄影0001机械朱家诚02002350机械原理课程设计0001机械王勇02002350机械原理课程设计0002机械朱立红02002350机械原理课程设计0003机械吴天星02002350机械原理课程设计0004机械汪进02002350机械原理课程设计0005机械朱立红02002350机械原理课程设计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HDL数字系统设电气孔慧芳04200220自动控制理论A0001电气胡乐平04001090电工与电子技术(Ⅱ)0001电气江萍04001090电工与电子技术(Ⅱ)0002电气徐晓冰04001090电工与电子技术(Ⅱ)0003电气李玉长04001090电工与电子技术(Ⅱ)0004电气杨安庆04001090电工与电子技术(Ⅱ)0005电气陈湘波04001090电工与电子技术(Ⅱ)0006电气苗刚中04001090电工与电子技术(Ⅱ)0007电气江兵04001090电工与电子技术(Ⅱ)0008电气杨庆04001090电工与电子技术(Ⅱ)0009电气李小燕04001090电工与电子技术(Ⅱ)0010电气江萍04001090电工与电子技术(Ⅱ)0011电气徐晓冰04001090电工与电子技术(Ⅱ)0012电气李玉长04001090电工与电子技术(Ⅱ)0013电气杨安庆04001090电工与电子技术(Ⅱ)0014电气陈湘波04001090电工与电子技术(Ⅱ)0015电气江兵04001090电工与电子技术(Ⅱ)0017电气李小燕04001090电工与电子技术(Ⅱ)0019电气胡乐平04001090电工与电子技术(Ⅱ)0020电气杨庆04001090电工与电子技术(Ⅱ)0021电气余琼芳04001110电工技术0001电气潘平04001110电工技术0002电气马红杰04001110电工技术0003电气魏常勇04001110电工技术0004电气吴敏04001110电工技术0005电气史明光04001110电工技术0006电气张晨彧04001110电工技术0007电气蒋琳04001110电工技术0008电气潘平04001110电工技术0010电气马红杰04001110电工技术0011电气魏常勇04001110电工技术0012电气吴敏04001110电工技术0013电气史明光04001110电工技术0014电气张晨彧04001110电工技术0015电气蒋琳04001110电工技术0016电气尹均萍04001110电工技术0018电气赵锐04001110电工技术0019电气张晨彧04001110电工技术0020电气钱自拓04001120电工与电子技术(Ⅰ)0001电气尹均萍04100720电路分析原理0001电气刘健04400120电路理论A0001电气刘良成04400120电路理论A0002电气叶运骅04400120电路理论A0003电气陈波04400120电路理论A0004电气刘健04400220电路理论B0001电气刘良成04400220电路理论B0002电气叶运骅04400220电路理论B0003电气陈波04400220电路理论B0004电气丁明,孙鸣,王群京04001800电气工程及其自动化专00010001电气刘健,陈强,陈波04001810生物医学工程专业导论电气张崇巍04001820自动化专业导论00010001计算机丁志中05000140信息论与编码(通信01)计算机李心科05000370软件工程(Ⅱ)0001计算机李心科05000370软件工程(Ⅱ)0002计算机蒋建国,夏娜05000480信息论0001计算机蒋建国,夏娜05000480信息论0002计算机吴从中05000650交换技术(通信)0001计算机昂志敏,尤小泉05000660微波电子线路0001计算机夏杨05000720光纤通信0001计算机李琳05000750多媒体技术(计算机)0001。

2001-2010考研英语(一)真题与解析

2001-2010考研英语(一)真题与解析

2001年全国硕士研究生入学统一考试英语试题Section I Structure and VocabularyPart ADirections:Beneath each of the following sentences, there are four choices marked [A], [B], [C] and [D]. Choose the one that best completes the sentence. Mark your answer on ANSWER SHEET 1 by blackening the corresponding letter in the brackets with a pencil. (5 points)Example:I have been to the Great Wall three times ________ 1979.[A] from[B] after[C] for[D] sinceThe sentence should read, “I have been to the Great Wall three times since 1979.” Therefore, you should choose [D].Sample Answer[A] [B] [C] [■]1. If I were in movie, then it would be about time that I ________ my head in my hands for a cry.[A] bury[B] am burying[C] buried[D] would bury2. Good news was sometimes released prematurely, with the British recapture of the port________ half a day before the defenders actually surrendered.[A] to announce[B] announced[C] announcing[D] was announced3. According to one belief, if truth is to be known it will make itself apparent, so one ________wait instead of searching for it.[A] would rather[B] had to[C] cannot but[D] had best4. She felt suitably humble just as she ________ when he had first taken a good look at her cityself, hair waved and golden, nails red and pointed.[A] had[B] had had[C] would have and[D] has had5. There was no sign that Mr. Jospin, who keeps a firm control on the party despite ________from leadership of it, would intervene personally.[A] being resigned[B] having resigned[C] going to resign[D] resign6. So involved with their computers ________ that leaders at summer computer camps often haveto force them to break for sports and games.[A] became the children[B] become the children[C] had the children become[D] do the children become7. The individual TV viewer invariably senses that he or she is ________ an anonymous,statistically insignificant part of a huge and diverse audience.[A] everything except[B] anything but[C] no less than[D] nothing more than8. One difficulty in translation lies in obtaining a concept match. ________ this is meant that aconcept in one language is lost or changed in meaning in translation.[A] By[B] In[C] For[D] With9. Conversation becomes weaker in a society that spends so much time listening and being talkedto ________ it has all but lost the will and the skill to speak for itself.[A] as[B] which[C] that[D] what10. Church as we use the word refers to all religious institutions, ________ they Christian, Islamic,Buddhist, Jewish, and so on.[A] be[B] being[C] were[D] arePart BDirections:Beneath each of the following sentences, there are four choices marked [A], [B], [C] and [D]. Choose the one that best completes the sentence. Mark your answer on ANSWER SHEET 1 by blackening the corresponding letter in the rackets with a pencil. (10 points)Example:The lost car of the Lees was found ________ in the woods off the highway.[A] vanished[B] scattered[C] abandoned[D] rejectedThe sentence should read. “The lost car of the Lees was found abandoned in the woods off the highway.” There fore, you should choose [C].Sample Answer[A] [B] [■][D]11. He is too young to be able to ________ between right and wrong.[A] discard[B] discern[C] disperse[D] disregard12. It was no ________ that his car was seen near the bank at the time of the robbery.[A] coincidence[B] convention[C] certainty[D] complication13. One of the responsibilities of the Coast Guard is to make sure that all ships ________ followtraffic rules in busy harbors.[A] cautiously[B] dutifully[C] faithfully[D] skillfully14. The Eskimo is perhaps one of the most trusting and considerate of all Indians but seems to be________ the welfare of his animals.[A] critical about[B] indignant at[C] indifferent to[D] subject to15. The chairman of the board ________ on me the unpleasant job of dismissing good workers thefirm can no longer afford to employ.[A] compelled[B] posed[C] pressed[D] tempted16. It is naive to expect that any society can resolve all the social problems it is faced with________.[A] for long[B] in and out[C] once for all[D] by nature17. Using extremely different decorating schemes in adjoining rooms may result in ________ andlack of unity in style.[A] conflict[B] confrontation[C] disturbance[D] disharmony18. The Timber rattlesnake is now on the endangered species list, and is extinct in two easternstates in which it once ________.[A] thrived[B] swelled[C] prospered[D] flourished19. However, growth in the fabricated metals industry was able to ________ some of the decline inthe iron and steel industry.[A] overturn[B] overtake[C] offset[D] oppress20. Because of its intimacy, radio is usually more than just a medium; it is ________.[A] firm[B] company[C] corporation[D] enterprise21. When any non-human organ is transplanted into a person, the body immediately recognizes itas ________.[A] novel[B] remote[C] distant[D] foreign22. My favorite radio song is the one I first heard on a thick 1923 Edison disc I ________ at agarage sale.[A] trifled with[B] scraped through[C] stumbled upon[D] thirsted for23. Some day software will translate both written and spoken language so well that the need forany common second language could ________.[A] descend[B] decline[C] deteriorate[D] depress24. Equipment not ________ official safety standards has all been removed from the workshop.[A] conforming to[B] consistent with[C] predominant over[D] providing for25. As an industry, biotechnology stands to ________ electronics in dollar volume and perhapssurpass it in social impact by 2020.[A] contend[B] contest[C] rival[D] strive26. The authors of the United States Constitution attempted to establish an effective nationalgovernment while preserving ________ for the states and liberty for individuals.[A] autonomy[B] dignity[C] monopoly[D] stability27. For three quarters of its span on Earth, life evolved almost ________ as microorganisms.[A] precisely[B] instantly[C] initially[D] exclusively28. The introduction of gunpowder gradually made the bow and arrow ________, particularly inWestern Europe.[A] obscure[B] obsolete[C] optional[D] overlapping29. Whoever formulated the theory of the origin of the universe, it is just ________ and needsproving.[A] spontaneous[B] hypothetical[C] intuitive[D] empirical30. The future of this company is ________: many of its talented employees are flowing into moreprofitable net-based businesses.[A] at odds[B] in trouble[C] in vain[D] at stakeSection II Cloze TestDirections:For each numbered blank in the following passage, there are four choices marked [A], [B], [C] and [D]. Choose the best one and mark your answer on ANSWER SHEET 1by blackening the corresponding letter in the brackets with a pencil. (10 points)The government is to ban payments to witnesses by newspapers seeking to buy up people involved in prominent cases 31the trial of Rosemary West.In a significant 32of legal controls over the press, Lord Irvine, the Lord Chancellor, will introduce a 33bill that will propose making payments to witnesses 34and will strictly control the amount of 35that can be given to a case 36 a trial begins.In a letter to Gerald Kaufman, chairman of the House of Commons Media Select Committee, Lord Irvine said he 37with a committee report this year which said that self regulation did not 38sufficient control.39of the letter came two days after Lord Irvine caused a 40of media protest when he said the 41of privacy controls contained in European legislation would be left to judges 42to Parliament.The Lord Chancellor said introduction of the Human Rights Bill, which 43theEuropean Convention on Human Rights legally 44in Britain, laid down that everybody was 45to privacy and that public figures could go to court to protect themselves and their families.“Press freedoms will be in safe hands 46our British judges,” he said.Witness payments became an 47after West was sentenced to 10 life sentences in 1995. Up to 19 witnesses were 48to have received payments for telling their stories to newspapers. Concerns were raised 49witnesses might be encouraged to exaggerate their stories in court to 50guilty verdicts.31. [A] as to [B] for instance [C] in particular [D] such as32. [A] tightening [B] intensifying [C] focusing [D] fastening33. [A] sketch [B] rough [C] preliminary [D] draft34. [A] illogical [B] illegal [C] improbable [D] improper35. [A] publicity [B] penalty [C] popularity [D] peculiarity36. [A] since [B] if [C] before [D] as37. [A] sided [B] shared [C] complied [D] agreed38. [A] present [B] offer [C] manifest [D] indicate39. [A] Release [B] Publication [C] Printing [D] Exposure40. [A] storm [B] rage [C] flare [D] flash41. [A] translation [B] interpretation [C] exhibition [D] demonstration42. [A] better than [B] other than [C] rather than [D] sooner than43. [A] changes [B] make [C] sets [D] turns44. [A] binding [B] convincing [C] restraining [D] sustaining45. [A] authorized [B] credited [C] entitled [D] qualified46. [A] with [B] to [C] from [D] by47. [A] impact [B] incident [C] inference [D] issue48. [A] stated [B] remarked [C] said [D] told49. [A] what [B] when [C] which [D] that50. [A] assure [B] confide [C] ensure [D] guaranteeSection III Reading ComprehensionDirections:Each of the passages below is followed by some questions. For each question there are four answers marked [A], [B], [C] and [D]. Read the passages carefully and choose the best answer to each of the questions. Then mark your answer on ANSWER SHEET 1 by blackening the corresponding letter in the brackets with a pencil. (40 points)Text 1Specialization can be seen as a response to the problem of an increasing accumulation of scientific knowledge. By splitting up the subject matter into smaller units, one man could continue to handle the information and use it as the basis for further research. But specialization was only one of a series of related developments in science affecting the process of communication. Another was the growing professionalisation of scientific activity.No clear-cut distinction can be drawn between professionals and amateurs in science: exceptions can be found to any rule. Nevertheless, the word “amateur” does carry a connotation that the person concerned is not fully integrated into the scientific community and, in particular, may not fully share its values. The growth of specialization in the nineteenth century, with its consequent requirement of a longer, more complex training, implied greater problems for amateur participation in science. The trend was naturally most obvious in those areas of science based especially on a mathematical or laboratory training, and can be illustrated in terms of the development of geology in the United Kingdom.A comparison of British geological publications over the last century and a half reveals not simply an increasing emphasis on the primacy of research, but also a changing definition of what constitutes an acceptable research paper. Thus, in the nineteenth century, local geological studies represented worthwhile research in their own right; but, in the twentieth century, local studies have increasingly become acceptable to professionals only if they incorporate, and reflect on, the wider geological picture. Amateurs, on the other hand, have continued to pursue local studies in the old way. The overall result has been to make entrance to professional geological journals harder for amateurs, a result that has been reinforced by the widespread introduction of refereeing, first by national journals in the nineteenth century and then by several local geological journals in thetwentieth century. As a logical consequence of this development, separate journals have now appeared aimed mainly towards either professional or amateur readership. A rather similar process of differentiation has led to professional geologists coming together nationally within one or two specific societies, whereas the amateurs have tended either to remain in local societies or to come together nationally in a different way.Although the process of professionalisation and specialization was already well under way in British geology during the nineteenth century, its full consequences were thus delayed until the twentieth century. In science generally, however, the nineteenth century must be reckoned as the crucial period for this change in the structure of science.51. The growth of specialization in the 19th century might be more clearly seen in sciences such as________.[A] sociology and chemistry[B] physics and psychology[C] sociology and psychology[D] physics and chemistry52. We can infer from the passage that ________.[A] there is little distinction between specialization and professionalisation[B] amateurs can compete with professionals in some areas of science[C] professionals tend to welcome amateurs into the scientific community[D] amateurs have national academic societies but no local ones53. The author writes of the development of geology to demonstrate ________.[A] the process of specialization and professionalisation[B] the hardship of amateurs in scientific study[C] the change of policies in scientific publications[D] the discrimination of professionals against amateurs54. The direct reason for specialization is ________.[A] the development in communication[B] the growth of professionalisation[C] the expansion of scientific knowledge[D] the splitting up of academic societiesText 2A great deal of attention is being paid today to the so-called digital divide -- the division of the world into the info (information) rich and the info poor. And that divide does exist today. My wife and I lectured about this looming danger twenty years ago. What was less visible then, however,were the new, positive forces that work against the digital divide. There are reasons to be optimistic.There are technological reasons to hope the digital divide will narrow. As the Internet becomes more and more commercialized, it is in the interest of business to universalize access -- after all, the more people online, the more potential customers there are. More and more governments, afraid their countries will be left behind, want to spread Internet access. Within the next decade or two, one to two billion people on the planet will be netted together. As a result, I now believe the digital divide will narrow rather than widen in the years ahead. And that is very good news because the Internet may well be the most powerful tool for combating world poverty that we’ve ever had.Of course, the use of the Internet isn’t the only way to defeat poverty. And the Int ernet is not the only tool we have. But it has enormous potential.To take advantage of this tool, some impoverished countries will have to get over their outdated anti-colonial prejudices with respect to foreign investment. Countries that still think foreign investment is an invasion of their sovereignty might well study the history of infrastructure (the basic structural foundations of a society) in the United States. When the United States built its industrial infrastructure, it didn’t have the capital to do so. And that is why America’s Second Wave infrastructure -- including roads, harbors, highways, ports and so on -- were built with foreign investment. The English, the Germans, the Dutch and the French were investing in Britain’s former colony. They financed them. Immigrant Americans built them. Guess who owns them now? The Americans. I believe the same thing would be true in places like Brazil or anywhere else for that matter. The more foreign capital you have helping you build your Third Wave infrastructure, which today is an electronic infrastructure, the better off you’re going to be. That doesn’t mean lying down and becoming fooled, or letting foreign corporations run uncontrolled. But it does mean recognizing how important they can be in building the energy and telecom infrastructures needed to take full advantage of the Internet.55. Digital divide is something ________.[A] getting worse because of the Internet[B] the rich countries are responsible for[C] the world must guard against[D] considered positive today56. Governments attach importance to the Internet because it ________.[A] offers economic potentials[B] can bring foreign funds[C] can soon wipe out world poverty[D] connects people all over the world57. The writer mentioned the case of the United States to justify the policy of ________.[A] providing financial support overseas[B] preventing foreign capital’s control[C] building industrial infrastructure[D] accepting foreign investment58. It seems that now a country’s economy depends much on ________.[A] how well-developed it is electronically[B] whether it is prejudiced against immigrants[C] whether it adopts America’s industrial pattern[D] how much control it has over foreign corporationsText 3Why do so many Americans distrust what they read in their newspapers? The American Society of Newspaper Editors is trying to answer this painful question. The organization is deep into a long self-analysis known as the journalism credibility project.Sad to say, this project has turned out to be mostly low-level findings about factual errors and spelling and grammar mistakes, combined with lots of head-scratching puzzlement about what in the world those readers really want.But the sources of distrust go way deeper. Most journalists learn to see the world through a set of standard templates (patterns) into which they plug each day’s events. In other words, there is a conventional story line in the newsroom culture that provides a backbone and a ready-made narrative structure for otherwise confusing news.There exists a social and cultural disconnect between journalists and their readers, which helps explain why the “standard templates” of the newsroom seem alien to many readers. In a recent survey, questionnaires were sent to reporters in five middle-size cities around the country, plus one large metropolitan area. Then residents in these communities were phoned at random and asked the same questions.Replies show that compared with other Americans, journalists are more likely to live in upscale neighborhoods, have maids, own Mercedeses, and trade stocks, and they’re less likely to go to church, do volunteer work, or put down roots in a community.Reporters tend to be part of a broadly defined social and cultural elite, so their work tends to reflect the conventional values of this elite. The astonishing distrust of the news media isn’t rooted in inaccuracy or poor reportorial skills but in the daily clash of world views between reporters and their readers.This is an explosive situation for any industry, particularly a declining one. Here is a troubled business that keeps hiring employees whose attitudes vastly annoy the customers. Then it sponsors lots of symposiums and a credibility project dedicated to wondering why customers are annoyed and fleeing in large numbers. But it never seems to get around to noticing the cultural and class biases that so many former buyers are complaining about. If it did, it would open up its diversity program, now focused narrowly on race and gender, and look for reporters who differ broadly by outlook, values, education, and class.59. What is the passage mainly about?[A] needs of the readers all over the world[B] causes of the public disappointment about newspapers[C] origins of the declining newspaper industry[D] aims of a journalism credibility project60. The results of the journalism credibility project turned out to be ________.[A] quite trustworthy[B] somewhat contradictory[C] very illuminating[D] rather superficial61. The basic problem of journalists as pointed out by the writer lies in their ________.[A] working attitude[B] conventional lifestyle[C] world outlook[D] educational background62. Despite its efforts, the newspaper industry still cannot satisfy the readers owing to its________.[A] failure to realize its real problem[B] tendency to hire annoying reporters[C] likeliness to do inaccurate reporting[D] prejudice in matters of race and genderText 4The world is going through the biggest wave of mergers and acquisitions ever witnessed. The process sweeps from hyperactive America to Europe and reaches the emerging countries with unsurpassed might. Many in these countries are looking at this process and worrying: “Won’t the wave of business concentration turn into an uncontrollable anti-competitive force?”There’s no question that the big are getting bigger and more powerful. Multinational corporations accounted for less than 20% of international trade in 1982. Today the figure is more than 25% and growing rapidly. International affiliates account for a fast-growing segment of production in economies that open up and welcome foreign investment. In Argentina, for instance, after the reforms of the early 1990s, multinationals went from 43% to almost 70% of the industrial production of the 200 largest firms. This phenomenon has created serious concerns over the role of smaller economic firms, of national businessmen and over the ultimate stability of the world economy.I believe that the most important forces behind the massive M&A wave are the same that underlie the globalization process: falling transportation and communication costs, lower trade andinvestment barriers and enlarged markets that require enlarged operations capable of meeting customer’s demands. All these are beneficial, not detrimental, to consumers. As productivity grows, the world’s wealth increases.Examples of benefits or costs of the current concentration wave are scanty. Yet it is hard to imagine that the merger of a few oil firms today could re-create the same threats to competition that were feared nearly a century ago in the U.S., when the Standard Oil Trust was broken up. The mergers of telecom companies, such as WorldCom, hardly seem to bring higher prices for consumers or a reduction in the pace of technical progress. On the contrary, the price of communications is coming down fast. In cars, too, concentration is increasing -- witness Daimler and Chrysler, Renault and Nissan -- but it does not appear that consumers are being hurt.Yet the fact remains that the merger movement must be watched. A few weeks ago, Alan Greenspan warned against the megamergers in the banking industry. Who is going to supervise, regulate and operate as lender of last resort with the gigantic banks that are bein g created? Won’t multinationals shift production from one place to another when a nation gets too strict about infringements to fair competition? And should one country take upon itself the role of “defending competition” on issues that affect many ot her nations, as in the U.S. vs. Microsoft case?63. What is the typical trend of businesses today?[A] to take in more foreign funds[B] to invest more abroad[C] to combine and become bigger[D] to trade with more countries64. According to the author, one of the driving forces behind M&A wave is ________.[A] the greater customer demands[B] a surplus supply for the market[C] a growing productivity[D] the increase of the world’s wealth65. From Paragraph 4 we can infer that ________.[A] the increasing concentration is certain to hurt consumers[B] WorldCom serves as a good example of both benefits and costs[C] the costs of the globalization process are enormous[D] the Standard Oil Trust might have threatened competition66. Toward the new business wave, the writer’s attitude can be said to be ________.[A] optimistic[B] objective[C] pessimistic[D] biasedText 5When I decided to quit my full time employment it never occurred to me that I might become a part of a new international trend. A lateral move that hurt my pride and blocked my professional progress prompted me to abandon my relatively high profile career although, in the manner of a disgraced government minister, I covered my exit by claiming “I wanted to spend more time with my family”.Curiously, some two-and-a-half years and two novels later, my experiment in what the Americans term “downshifting” has turned my tired excuse into an absolute reality. I have been transformed from a passionate advocate of the philosophy of “having it all,” preached by Linda Kelsey for the past seven years in the page of She magazine, into a woman who is happy to settle for a bit of everything.I have discovered, as perhaps Kelsey will after her much-publicized resignation from the editorship of She after a build-up of stress, that abandoning the doctrine of “juggling your life,” and making the alternative move into “downshifting” brings with it far greater rewards than financial success and social status. Nothing could persuade me to return to the kind of life Kelsey used to advocate and I once enjoyed: 12-hour working days, pressured deadlines, the fearful strain of office politics and the limitations of being a parent on “quality time”.In America, the move away from juggling to a simpler, less materialistic lifestyle is a well-established trend. Downshifting -- also known in America as “voluntary simplicity” -- has, ironically, even bred a new area of what might be termed anti-consumerism. There are a number of best-selling downshifting self-help books for people who want to simplify their lives; there are newsletters, such as The Tightwad Gazette, that give hundreds of thousands of Americans useful tips on anything from recycling their cling-film to making their own soap; there are even support groups for those who want to achieve the mid-’90s equivalent of dropping out.While in America the trend started as a reaction to the economic decline -- after the mass redundancies caused by downsizing in the late ’80s -- and is still linked to the politics of thrift, in Britain, at least among the middle-class downshifters of my acquaintance, we have different reasons for seeking to simplify our lives.For the women of my generation who were urged to keep juggling through the ’80s, downshifting in the mid-’90s is not so much a search for the mythical good life -- growing your own organic vegetables, and risking turning into one -- as a personal recognition of your limitations.67. Which of the following is true according to Paragraph 1?[A] Full-time employment is a new international trend.[B] The writer was compelled by circumstances to leave her job.[C] “A lateral move” means stepping out of full-time employment.[D] The writer was only too eager to spend more time with her family.68. The writer’s experiment shows that downshifting ________.[A] enables her to realize her dream[B] helps her mold a new philosophy of life[C] prompts her to abandon her high social status[D] leads her to accept the doctrine of She magazine69. “Juggling one’s life” probably means living a life characterized by ________.[A] non-materialistic lifestyle[B] a bit of everything[C] extreme stress[D] anti-consumerism70. According to the passage, downshifting emerged in the U.S. as a result of ________.[A] the quick pace of modern life[B] man’s adventurous spirit[C] man’s search for mythical experiences[D] the economic situationSection IV English-Chinese TranslationDirections:Read the following passage carefully and then translate the underlined sentences into Chinese. Your translation must be written neatly on ANSWER SHEET 2. (15 points)In less than 30 years’ time the Star Trek holodeck will be a reality. Direct links between the brain’s nervous system and a computer will also create full sensory virtual environments, allowing virtual vacations like those in the film Total Recall.71) There will be television chat shows hosted by robots, and cars with pollution monitors that will disable them when they offend. 72) Children will play with dolls equipped with personality chips, computers with in-built personalities will be regarded as workmates rather than tools, relaxation will be in front of smell-television, and digital age will have arrived.According to BT’s futurologist, Ian Pearson, these are among the developments scheduled for the first few decades of the new millennium (a period of 1,000 years), when supercomputers will dramatically accelerate progress in all areas of life.73) Pearson has pieced together the work of hundreds of researchers around the world to produce a unique millennium technology calendar that gives the latest dates when we can expect hundreds of key breakthroughs and discoveries to take place. Some of the biggest developments will be in medicine, including an extended life expectancy and dozens of artificial organs coming into use between now and 2040.Pearson also predicts a breakthrough in computer-human links. “By linking directly to our nervous system, computers could pick up what we feel and, hopefully, simulate feeling too so that we can start to develop full sensory environments, rather like the holidays in Total Recall or the Star。

J Pharmacol Exp Ther-2010-Arai-206-13[1]

J Pharmacol Exp Ther-2010-Arai-206-13[1]

Metformin,an Antidiabetic Agent,Suppresses the Production of Tumor Necrosis Factor and Tissue Factor by Inhibiting Early Growth Response Factor-1Expression in Human Monocytes in VitroMasatoku Arai,Mitsuhiro Uchiba,Hidefumi Komura,Yuichiro Mizuochi,Naoaki Harada,and Kenji OkajimaDepartments of Translational Medical Science Research (M.A.,N.H.,K.O.)and Anesthesiology and Medical Crisis Management (H.K.,Y.M.),Nagoya City University Graduate School of Medical Sciences,Nagoya,Japan;and Department of Blood Transfusion and Cell Therapy,Kumamoto University Hospital,Kumamoto,Japan (M.U.)Received December 24,2009;accepted March 31,2010ABSTRACTMetformin,an antidiabetic agent,has been shown to reduce atherothrombotic disease in diabetic patients independent of antihyperglycemic effect.Recent studies have demonstrated that metformin attenuates the proinflammatory responses in human vascular wall cells and macrophages.However,the detailed molecular mechanisms underlying these therapeutic effects remain unclear.In the present study,we investigated the effects of metformin on tumor necrosis factor (TNF)pro-duction and tissue factor (TF)expression in isolated human monocytes stimulated with lipopolysaccharide (LPS)or oxi-dized low-density lipoprotein (oxLDL).Metformin significantly inhibited both TNF production and TF expression in isolatedhuman monocytes stimulated with LPS or oxLDL.Metformin also significantly inhibited TNF and TF mRNA in human monocytes stimulated with LPS.Although metformin did not inhibit the activation of either nuclear factor-␬B or activator protein-1,it inhibited the expression of early growth re-sponse factor-1(Egr-1)and phosphorylation of extracellular signal-regulated protein kinase (ERK)1/2in monocytes stim-ulated with LPS or oxLDL.These results suggest that met-formin may attenuate the inflammatory responses,at least in part,by suppressing the production of both TNF and TF through the inhibition of the ERK1/2-Egr-1pathway in human monocytes.Metformin is one of the most commonly used antidiabetic agents.It improves insulin sensitivity in patients with type 2diabetes (Stumvoll et al.,1995).In addition,metformin re-duces the risk of atherothrombotic disease accompanied with diabetes independent of its antihyperglycemic effect (UK Prospective Diabetes Study Group,1998).It is now well accepted that atherosclerosis is not merely a lipid disorder,but also an inflammatory disease (Ross,1999;Libby,2002).Inflammatory cells,such as monocytes/macro-phages,play a critical role in the initiation,progression,and complication of atherosclerotic lesions (Ross,1999;Libby,2002).Various cytokines contribute to pathogenesis of inflamma-tion observed in atherosclerosis (Kleemann et al.,2008).Among these cytokines,tumor necrosis factor (TNF)plays an important role.TNF is shown to be present in atherosclerotic lesions but not in normal vessels in humans (Tipping and Hancock,1993).TNF is associated with the progression of atherosclerotic lesions by regulating the functions of vascular wall cells to promote adhesion,migration,growth,and acti-vation of leukocytes (Young et al.,2002),thus leading to the further accumulation of mononuclear phagocytes and ampli-fication of inflammation (Ross,1999;Libby,2002).TNF is also associated with complications of atherosclerosis by in-creasing the production of matrix metalloproteinases contrib-uting to the vulnerability of the fibrous cap (Young et al.,2002).The activation of coagulation also contributes to the patho-genesis of atherosclerosis (Ross,1999;Libby,2002).Tissue factor (TF)is an important factor initiating blood coagulationArticle,publication date,and citation information can be found at .doi:10.1124/jpet.109.164970.ABBREVIATIONS:TNF,tumor necrosis factor;AMPK,AMP-activated protein kinase;AP-1,activator protein-1;Egr-1,early growth response factor-1;ELISA,enzyme-linked immunosorbent assay;ERK,extracellular signal-regulated protein kinase;JNK,c-Jun N-terminal kinase;LPS,lipopolysaccharide;NF-␬B,nuclear factor-␬B;oxLDL,oxidized low-density lipoprotein;TF,tissue factor;RT-PCR,reverse transcription-poly-merase chain reaction;I ␬〉,inhibitor ␬B.0022-3565/10/3341-206–213$20.00T HE J OURNAL OF P HARMACOLOGY AND E XPERIMENTAL T HERAPEUTICSVol.334,No.1Copyright ©2010by The American Society for Pharmacology and Experimental Therapeutics 164970/3596086JPET 334:206–213,2010Printed in U.S.A.206at NSTL on May 14, 2012Downloaded from(Edgington et al.,1991),which is expressed in atheroscleroticlesions in humans(Tipping et al.,1989;Wilcox et al.,1989). Current evidence suggests that the exposure of TF-positive monocyte-derived macrophages to blood on plaque disruption may trigger both intravascular thrombosis and a sudden progression of atherosclerotic lesions(Libby,2002). Although various causes contributing to the pathogenesis of inflammation observed in atherosclerosis have been iden-tified,oxidized low-density lipoprotein(oxLDL)in hypercho-lesterolemia and lipopolysaccharide(LPS)from infectious microorganisms are recognized as potentially important sources of chronic inflammation in the development of ath-erosclerotic lesions(Ross,1999;Libby,2002).In the present study,we examined whether metformin inhibits TNF production and TF expression in human mono-cytes stimulated with LPS or oxLDL and attempted to iden-tify the underlying molecular mechanisms.Materials and MethodsMaterials.Metformin(1,1-dimethylbiguanide)was a generous gift from Nippon Shinyaku Co.,Ltd.(Kyoto,Japan).LPS(Esche-richia coli,serotype055:B5)was purchased from Sigma-Aldrich(St. Louis,MO).oxLDL was purchased from Intracel Resources,LLC (Frederick,MD).Polyclonal rabbit antibodies against inhibitor␬B (I␬〉)␣,p38,phosphorylated p38(Thr180/Tyr182),c-Jun N-terminal kinase(JNK),phosphorylated JNK(Thr183/Tyr185),extracellular signal-regulated protein kinase(ERK)1/2,phosphorylated ERK1/2 (Thr202/Tyr204),early growth response factor-1(Egr-1),and caspase-3were purchased from Cell Signaling Technology(Danvers, MA).Antibodies against PU.1and␤-actin were obtained from Santa Cruz Biotechnology,Inc.(Santa Cruz,CA).All reagents used were of analytical grade.Monocyte Preparation and Incubation.Human peripheral blood mononuclear cells were isolated from buffy coats provided by the local Central Institute of Blood Transfusion or obtained from healthy volunteer blood donors by Ficoll-Hypaque density gradi-ent centrifugation on Lymphoprep(Axis-Shield poC AS,Oslo, Norway)and then were further fractionated as described previ-ously(Uchiba et al.,1997).This study was performed with the approval of the ethics committee of the Nagoya City University Graduate School of Medical Sciences,and blood donors enrolled for the study gave informed consent in accordance with the Dec-laration of Helsinki.To minimize any possible interindividual variation among blood donors,each experiment was conducted by using monocytes from two to four buffy coats and repeated three times by using independent mononuclear cell preparations from different donors.The mononuclear cells in plastic dishes with RPMI medium1640(Invitrogen,Carlsbad,CA)supplemented with1%calf serum(HyClone Laboratories,Logan,UT)were in-cubated for16h at37°C in a humidified5%CO2incubator. Lymphocytes were then removed from the adherent monocytes by repeated rinsing with serum-free RPMI medium1640.The result-ing cell preparations wereϾ90%monocytes,as determined by May-Giemsa staining.Cell viability wasϾ95%,as determined by a trypan blue dye exclusion test.Monocytes thus obtained were adjusted to an appropriate volume and cultured in RPMI medium 1640supplemented with1%calf serum at37°C in a humidified5%CO2incubator.Various concentrations of metformin were added to cells at2h before stimulation with LPS(100ng/ml)or oxLDL (8␮g/ml).After further incubation under the same culture condi-tions for the required period,the cell suspensions were centri-fuged.The resulting supernatant fractions were used to deter-mine the levels of TNF,and the sedimented mononuclear pellets were used for TF activity measurements.Measurement of TNF Level.Human monocytes(1ϫ106cells/ assay)were stimulated with LPS for6h or oxLDL for12h in the presence or absence of metformin.The concentrations of TNF inculture media were determined by using an enzyme-linked immu-nosorbent assay(ELISA)kit for human TNF(BioSource Interna-tional,Camarillo,CA).Measurement of TF Activity.Human monocytes(1ϫ106cells/ assay)were stimulated with either LPS or oxLDL for6h in the presence or absence of metformin.The TF activities on monocyteswere measured as described previously(Molor-Erdene et al.,2005).In brief,human monocytes(1ϫ106cells)were washed twice by a phosphate-buffered saline and then stored atϪ80°C until TF activitywas measured.After thawing,the cell pellets were sonicated for30sto scrap the monocyte pellets and then dissolved in100␮l of clottingbuffer(12mM sodium acetate,7mM diethylbarbitate,and130mM sodium chloride).Fifty microliters of the resuspended cells wasmixed with50␮l of citrated plasma,and the clotting times were measured after recalcification with50␮l of20mM CaCl2solution at37°C.The TF equivalents were determined by using a standardcurve obtained from rabbit brain thromboplastin(Neoplastin Plus;Roche Diagnostic,Mannheim,Germany).Detection of Specific Binding of p65,p50,and c-Fos to DNAby Enzyme-Linked Immunosorbent Assay.Human monocytes(1ϫ107cells/assay)were stimulated with either LPS or oxLDL for1h in the presence or absence of metformin.Nuclear extracts were prepared as described previously(Yuksel et al.,2003).The specific binding of p65,p50,and c-Fos to their DNA consensus oligonucleo-tides was evaluated in nuclear extracts by using ELISA-based assaykits(Trans AM;Active Motif Inc.,Carlsbad,CA)as described previ-ously(Molor-Erdene et al.,2005).RNA Isolation and Quantitative mRNA Analysis.RT-PCRassays were used to assess TNF and TF mRNA levels in culturedhuman monocytes.Total RNA was extracted from cultured human monocytes by using TRIzol reagent(Invitrogen)according to the manufacturer’s instruction.This procedure yielded5to10␮g oftotal RNA from5ϫ105cells of cultured human monocytes.RNA samples were diluted in RNase-free water and stored atϪ80°Cuntil they were used.Real-time PCR was performed by using theABI PRISM7700Sequence Detection System,TaqMan One-StepRT-PCR Master Mix Reagents Kit,and commercially available predesigned,gene-specific primers and FAM-labeled probe setsfor quantitative gene expression(TaqMan Gene Expression As-says;human TNF code Hs00174128_m1,human TF codeHs00175225_ml,and human glyceraldehyde3-phosphate dehy-drogenase code Hs99999905_m1;Applied Biosystems,Foster City, CA).All probes used in these experiments spanned an exon–intron boundary.TNF,TF,and glyceraldehyde3-phosphate dehydroge-nase mRNA were quantified by parallel estimation.The thermalcycler conditions were30-min hold at48°C and10-min hold at95°C,followed by40cycles of15s at95°C and1min at60°C.Western Blot Analysis.Human monocytes(2ϫ106cells/assay)were stimulated with LPS or oxLDL for various times in the presenceor absence of metformin(10␮M).Whole-cell lysates were collected as described previously(Komura et al.,2008).Samples containingequal amounts of protein were separated by using sodium dodecylsulfate-polyacrylamide gel electrophoresis,and after electrophoresis,the proteins were transferred onto a polyvinylidene difluoride mem-brane(Bio-Rad Laboratories,Hercules,CA).The membranes were incubated with appropriate antibodies at4°C overnight and then subsequently with horseradish peroxidase-conjugated secondary an-tibody for1h at room temperature.Specific proteins were visualizedby using an enhanced chemiluminescence system(GE Healthcare,Little Chalfont,Buckinghamshire,UK).The densitometric quantifi-cation of the bands was performed by using National Institutes ofHealth Image software(version1.61).Cell Viability.Isolated monocytes were stimulated with LPS oroxLDL in the presence or absence of metformin.The number of monocytes was counted at6h after stimulation with LPS or12hInhibition of Egr-1Expression by Metformin207at NSTL on May 14, 2012Downloaded fromafter stimulation with oxLDL.Cell viability was evaluated by using a trypan blue dye exclusion test (Uchiba et al.,1997).Assessment of Apoptosis.Isolated monocytes were stimulated with LPS for 6h or oxLDL for 12h in the presence or absence of metformin (10␮M).Assessing the apoptosis of monocytes was performed by a Western blot analysis probed with anticaspase-3antibody.Statistical Analysis.The values are distributed in parametric manner and expressed as means ϮS.D.of one experiment represen-tative of three separate experiments that gave similar results.Dif-ferences in TNF production,TF activity,and mRNA levels were assessed by using analysis of variance followed by Scheffe ´’s post hoc test.In densitometric analysis data of Western blotting,the differ-ence between baseline values (time 0)and subsequent values for each experiment was compared by using analysis of variance fol-lowed by Scheffe ´’s post hoc test,and the differences between the values with and without metformin treatment at each time point were compared by unpaired t test.These analyses were carried out with StatView 5.0software (SAS Institute,Cary,NC).Statistical significance was defined as a level of p Ͻ0.05.ResultsEffect of Metformin on the Production of TNF and TF in Isolated Human Monocytes Stimulated with LPS.We examined the effect of metformin on LPS-induced increases in TNF production and TF activities in isolated human monocytes.We previously demonstrated that TNF production and TF activities by monocytes began to increase at 2h in monocytes stimulated with LPS (100ng/ml),peak-ing at 6h after the stimulation (Molor-Erdene et al.,2005;Komura et al.,2008).Metformin significantly inhibited the increases in both TNF production (Fig.1A;p Ͻ0.05)and TF activities (Fig.1B;p Ͻ0.05)in isolated monocytes after LPS stimulation.Metformin also inhibited the LPS-induced in-creases in TNF and TF mRNA levels in isolated human monocytes (Fig.2;p Ͻ0.05).The cell viability assessed by trypan blue dye exclusion test and apoptosis analyzed by Western blotting for caspase-3ruled out the possibility that the observed effects were caused by cell death in the experi-mental condition (data not shown).Effect of Metformin on the Activation of Nuclear Factor-␬B and Activator Protein-1Pathways in Iso-lated Human Monocytes Stimulated with LPS.Both NF-␬B and AP-1were demonstrated to be important tran-scription factors promoting the gene expression of TNF and TF in monocytes stimulated with LPS (Mackman,1995;Hambleton et al.,1996;Guha et al.,2001).To deter-mine whether metformin inhibits LPS-induced activation of NF-␬B in monocytes,we examined the effect of met-formin on LPS-induced degradation of I ␬B ␣in isolated human monocytes.Metformin did not inhibit LPS-induced degradation of I ␬B ␣in monocytes (Fig.3A).In addition,metformin did not inhibit LPS-induced increases in the DNA-binding activities of p65and p50to their consensus oligonucleotides (data not shown).To determine whether metformin inhibits LPS-induced activation of AP-1,we examined the effect of metformin on LPS-induced phos-phorylation of p38and JNK in isolated human monocytes.Metformin did not inhibit LPS-induced phosphorylation of p38and JNK in monocytes (Fig.3B and C).In addition,metformin did not inhibit LPS-induced increases in DNA-binding activities of c-Fos to their consensus oligonucleo-tides (data not shown).Effect of Metformin on the Expression of Egr-1and Phosphorylation of ERK1/2in Isolated Human Mono-cytes Stimulated with LPS.Egr-1has been demonstrated to be an important transcription factor promoting the gene expression of TNF and TF in monocytes stimulated with LPS (Mackman,1995;Guha et al.,2001).To determine whether metformin inhibits LPS-induced activation of Egr-1in mono-cytes,we examined the effect of metformin on LPS-induced increases in the expression of Egr-1in isolated human mono-cytes.Intracellular levels of Egr-1increased after LPS stim-ulation,peaking at 60min after stimulation and decreasing thereafter (Fig.4A).Metformin significantly inhibited the increases of Egr-1expression after 60min in monocytes stimulated with LPS (Fig.4A;p Ͻ0.05).The activation of ERK1/2was shown to induce transcription of TNF and TF byFig.1.Effects of metformin on increases in TNF production and TF activities in isolated human monocytes stimulated with LPS.A,human monocytes were preincubated with various concentrations of metformin for 2h and then stimulated with LPS (100ng/ml).Six hours after the stimulation,the supernatants were collected and TNF levels were mea-sured by ELISA as described in Materials and Methods .Data presented are means ϮS.D.(n ϭ4)and are representative of three separate experiments that gave similar results.ء,p Ͻ0.01versus LPS (Ϫ)without metformin;†,p Ͻ0.05versus LPS (ϩ)without metformin.B,human monocytes were preincubated with various concentrations of metformin for 2h and then stimulated with LPS (100ng/ml).Six hours after the stimulation,mononuclear cell pellets were collected and TF activities were measured by using the clotting assay method as described in Ma-terials and Methods .Data presented are means ϮS.D.(n ϭ4)and are representative of three separate experiments that gave similar results.ء,p Ͻ0.01versus LPS (Ϫ)without metformin;†,p Ͻ0.05versus LPS (ϩ)without metformin.208Arai et al.at NSTL on May 14, 2012Downloaded fromincreasing the expression of Egr-1(Guha et al.,2001).To determine whether metformin inhibits LPS-induced activa-tion of ERK1/2,thereby suppressing Egr-1expression,we examined the effect of metformin on LPS-induced phosphor-ylation of ERK1/2in isolated human monocytes.Intracellu-lar levels of phosphorylated ERK1/2increased after LPS stimulation,peaking at30min and decreasing thereafter (Fig.4B).Metformin significantly inhibited LPS-induced phosphorylation of ERK1/2in monocytes at30min after stimulation(Fig.4B;pϽ0.05).Effect of Metformin on the Production of TNF and TF in Isolated Human Monocytes Stimulated with oxLDL.oxLDL has been reported to induce TNF production and TF activity in isolated human monocytes in vitro (Jovinge et al.,1996;Petit et al.,1999).The effect of met-formin on oxLDL-induced increases in TNF production and TF activities was examined in isolated human monocytes. Metformin(10␮M)significantly inhibited the increases in both TNF production(Fig.5A;pϽ0.05)and TF activities (Fig.5B;pϽ0.05)in isolated monocytes at12and6h after oxLDL(8␮g/ml)stimulation,respectively.The cell viability assessed by a trypan blue dye exclusion test and apoptosis analyzed by Western blotting for caspase-3ruled out the possibility that the observed effects were caused by cell death in the experimental conditions(data not shown).Effect of Metformin on the Activation of NF-␬B, AP-1,and ERK1/2-Egr-1Pathways in Isolated Human Monocytes Stimulated with oxLDL.We examined whether metformin inhibits oxLDL-induced activation of NF-␬B and AP-1in monocytes.Metformin did not inhibit degradation of I␬B␣,phosphorylation of p38and JNK,or DNA-binding activities of p65,p50,and c-Fos in isolated human monocytes stimulated with oxLDL(data not shown). To determine whether metformin inhibits oxLDL-in-duced activation of Egr-1in monocytes,we examined the effect of metformin on oxLDL-induced increases in the expression of Egr-1in isolated human monocytes.Intra-cellular levels of Egr-1increased after oxLDL stimulation, peaking at120min after stimulation and decreasing there-after(Fig.6A).Metformin significantly inhibited the in-creases of Egr-1expression at120min in monocytes stim-ulated with oxLDL(Fig.6A;pϽ0.05).To determine whether metformin inhibits oxLDL-induced activation of ERK1/2,thereby suppressing Egr-1expression,we exam-ined the effect of metformin on oxLDL-induced phosphor-ylation of ERK1/2in isolated human monocytes.Intracel-lular levels of phosphorylated ERK1/2increased after oxLDL stimulation,peaking at60min after stimulation and decreasing thereafter(Fig.6B).Metformin significantly inhib-ited oxLDL-induced phosphorylation of ERK1/2in monocytes at 60min after stimulation(Fig.6B;pϽ0.05).DiscussionIn the present study,we demonstrated that metformin inhibited the production of TNF and TF in isolated human monocytes stimulated with LPS or oxLDL.The monocytic production of TNF and TF is regulated by various transcriptional factors including NF-␬B,AP-1,and Egr-1(Mackman,1995;Jovinge et al.,1996;Guha et al., 2001).The activity of NF-␬B is regulated primarily via its sequestration in the cytosol by anchoring to inhibitor protein I␬B␣(Baldwin,1996).As shown in the present study,pre-treatment with metformin did not affect the degradation of I␬B␣or the increase in DNA-binding activity of p65and p50 induced by LPS or oxLDL.These results suggested that the inhibitory effect of metformin on the production of TNF and TF in LPS-or oxLDL-stimulated monocytes might not be mediated by the inhibition of NF-␬B pathway.AP-1is another important factor regulating the production of TNF and TF.The activation of p38and JNK by phosphor-ylation was shown to enhance the transcriptional activity of AP-1(Mackman,1995;Hambleton et al.,1996;Jovinge et al., 1996).In the present study,metformin did not inhibit LPS-or oxLDL-induced phosphorylation of JNK and p38or the increase in DNA-binding activity of c-Fos.These results sug-gest that the inhibitory effect of metformin on the production of TNF and TF in monocytes might not be caused by the inhibition of AP-1activation.Metformin,on the other hand,inhibited LPS-or oxLDL-induced increases in intracellular levels of Egr-1as shown inFig.2.Effects of metformin on increases in TNF and TF mRNA in isolated human monocytes stimulated with LPS.A,TNF mRNA levels in isolated human monocytes preincubated with or without metformin(10␮M)for2h were determined at1h after stimulation with LPS(100ng/ml).TNF mRNA levels in human monocytes were detected by quan-titative RT-PCR as described in Materials and Methods.Data presented are meansϮS.D.(nϭ3)and are representative of three separate experiments that gave similar results.ء,pϽ0.01versus LPS(Ϫ)without metformin;†,pϽ0.05versus LPS(ϩ)without metformin.B,TF mRNA levels in isolated human monocytes preincubated with or without met-formin(10␮M)for2h were determined at1h after stimulation with LPS (100ng/ml).TF mRNA levels in human monocytes were detected by quantitative RT-PCR as described in Materials and Methods.Data pre-sented are meansϮS.D.(nϭ3)and are representative of three separate experiments that gave similar results.ء,pϽ0.01versus LPS(Ϫ)without metformin;†,pϽ0.05versus LPS(ϩ)without metformin.Inhibition of Egr-1Expression by Metformin209at NSTL on May 14, 2012Downloaded fromthe present study.Egr-1is shown to be rapidly and tran-siently expressed in monocytes in response to LPS or oxLDL (Guha et al.,2001;Harja et al.,2004).Because Egr-1is critically involved in the production of TNF and TF by mono-cytes (Mackman,1995;Guha et al.,2001),metformin might inhibit the production of TNF and TF by inhibiting the acti-vation of Egr-1in monocytes stimulated with LPS or oxLDL.Egr-1gene expression is regulated by various transcriptional factors,including Elk-1and Sap-1a.Guha et al.(2001)re-ported that Elk-1,activated by phosphorylated-ERK1/2,plays an important role in the Egr-1expression induced by LPS.They also reported that an inhibitor of ERK1/2pathway reduces LPS-induced production of TNF and TF via inhibi-tion of Egr-1expression in monocytes.Because metformin inhibited LPS-or oxLDL-induced phosphorylation of ERK1/2in the present study,it is probable that metformin may inhibit the expression of Egr-1by inhibiting ERK1/2activa-tion,thereby suppressing the production of TNF and TF in monocytes stimulated with LPS or oxLDL.The precise mechanism by which metformin inhibits phosphorylation of ERK1/2in monocytes stimulated with LPS or oxLDL remains unclear at present.Metformin is known as a pharmacological activator of AMP-activated protein kinase (AMPK)in various cell types (Zou et al.,2004;Hattori et al.,2006).However,it still remains con-troversial whether metformin exhibits an anti-inflamma-tory effect through the activation of AMPK.Hattori et al.(2006)demonstrated that high concentrations of met-formin (Ͼ1mM)reduce TNF-induced NF-␬B activity through the activation of AMPK in human umbilical vein endothelial cells.Isoda et al.(2006)reported that met-formin reduces high-glucose induced proinflammatory sig-naling independent of AMPK activation in human saphe-nous vein endothelial cells.Another AMPK activator,5-aminoimidazole-4-carboxamide riboside,was shown to ex-hibit anti-inflammatory effects independent of the activation of AMPK in RAW264.7cells stimulated with LPS (Jhun et al.,2004;Kuo et al.,2008).These observations indicate that the inhibitory effects of metformin on the production of TNF and TF in LPS-or oxLDL-stimulated monocytes might be independent of its activation of AMPK.TNF plays a critical role in proinflammatory responses in the development of inflammation observed in the ath-erosclerotic lesions of the vasculature (Tipping and Han-cock,1993;Libby,2002).TNF can regulate the various functions of vascular wall cells.TNF induces expression of adhesion molecules such as vascular cell adhesion mole-cule-1,intercellular adhesion molecule-1,E-selectin,andFig.3.Effects of metformin on the deg-radation of I ␬B ␣and increases in intra-cellular levels of phosphorylated p38and phosphorylated JNK in isolated human monocytes stimulated with LPS.Isolated human monocytes pretreated with or without metformin (10␮M)for 2h were stimulated with LPS (100ng/ml)for the indicated times.Intracellular levels of I ␬B ␣(A),phosphorylated p38(p-p38)(B),and phosphorylated JNK (p-p54and p-p46)(C)in human monocytes were deter-mined by Western blot analysis.␤-Actin,nonphosphorylated p38(p38),and non-phosphorylated JNK (p54and p46)were detected as the loading control.The re-sults of a densitometric analysis are also shown.Data presented are means ϮS.D.of three samples in one experiment rep-resentative of three separate experiments that gave similar results.E ,LPS without metformin;F ,LPS with metformin.ء,p Ͻ0.01versus time 0.210Arai et al.at NSTL on May 14, 2012Downloaded fromP-selectin(Marui et al.,1993;Collins et al.,1995;Taka-hashi et al.,1996;Young et al.,2002),crucial to the re-cruitment of mononuclear leukocytes to endothelial cells. TNF also increases the production of monocyte chemoat-tractant protein-1and interleukin-8,which are capable of inducing the migration of mononuclear leukocytes into the intima(Rollins et al.,1990;Young et al.,2002).TNF aug-ments the production of macrophage colony-stimulating factor by vascular wall cells,which stimulates the transi-tion of monocytes to lipid-laden macrophages(foam cells). Consequently,it promotes the survival and growth of foam cells and increases production of cytokines and growth factors by foam cells(Libby,2002;Young et al.,2002). Therefore,TNF is involved in the accumulation of mono-nuclear phagocytes and amplification of inflammation of the lesions leading to the development of atherosclerosis. The degradation of extracellular matrix by matrix metal-loproteinases is thought to be important in plaque rupture (Young et al.,2002).TNF is shown to stimulate the expres-sion of various types of matrix metalloproteinases in en-dothelial cells and smooth muscle cells and macrophages (Young et al.,2002).Because the present study has shown that metformin inhibits TNF production in LPS-or oxLDL-stimulated human monocytes,it is possible that the inhi-bition of TNF production by metformin in monocytes mayFig.4.Effect of metformin on increases in intracellular levels of Egr-1 and phosphorylated ERK1/2in isolated human monocytes stimulated with LPS.A,isolated human monocytes pretreated with or without metformin(10␮M)for2h were stimulated with LPS(100ng/ml)for the indicated times.Intracellular levels of Egr-1in human monocytes were determined by Western blot analysis.PU.1was detected as the loading control.The results of a densitometric analysis are also shown.Data presented are meansϮS.D.of three samples in one experiment repre-sentative of three separate experiments that gave similar results.E,LPS without metformin;F,LPS with metformin.ء,pϽ0.01versus time0;†, pϽ0.05versus LPS without metformin.B,isolated human monocytes pretreated with or without metformin(10␮M)for2h were stimulated with LPS(100ng/ml)for the indicated times.Intracellular levels of phosphorylated ERK1/2(p-ERK1/2)in human monocytes were deter-mined by Western blot analysis.Nonphosphorylated ERK1/2(ERK1/2) was detected as the loading control.The results of a densitometric anal-ysis are also shown.Data presented are meansϮS.D.of three samples in one experiment representative of three separate experiments that gave similar results.E,LPS without metformin;F,LPS with metformin.ء,pϽ0.01versus time0;†,pϽ0.05versus LPS without metformin.Fig.5.Effects of metformin on increases in TNF production and TF activities in isolated human monocytes stimulated with oxLDL.A,human monocytes were preincubated with metformin(10␮M)for2h and then stimulated with oxLDL(8␮g/ml).Twelve hours after the stimulation,the supernatants were collected,and TNF levels were measured by ELISA as described in Materials and Methods.Data presented are meansϮS.D.(nϭ4)and are representative of three separate experiments that gave similar results.ء,pϽ0.01versusoxLDL(Ϫ)without metformin;†,pϽ0.05versus oxLDL(ϩ)without metformin.B,human monocytes were preincubated with metformin(10␮M)for2h and then stimulated with oxLDL(8␮g/ml).Six hoursafter the stimulation,mononuclear cell pellets were collected,and TF activities were measured by using the clotting assay method as de-scribed in Materials and Methods.Data presented are meansϮS.D.(nϭ4)and are representative of three separate experiments that gavesimilar results.ء,pϽ0.01versus oxLDL(Ϫ)without metformin;†,pϽ0.05versus oxLDL(ϩ)without metformin.Inhibition of Egr-1Expression by Metformin211at NSTL on May 14, 2012Downloaded from。

色卡-RAL-德国色表标准

色卡-RAL-德国色表标准

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AcuRev 2000 series Brochure (2010C1103)

AcuRev 2000 series Brochure (2010C1103)

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AcuRev 2000系列产品集成了多达18路单相(或6路三相)的电能计量、 参数测量和电能质量监测功能,是Accuenergy公司面向下一代智能配电 网开发的先进智能电表。具有集中安装、分户计量、一户一表、循环显 示、防止窃电等特点,非常适合大型商业设施、公寓宿舍、工业企业以 及住宅。产品具备红外通讯口、RS485通讯接口和以太网接口,可以便捷 地接入智能配电监控系统,产品还有丰富的 IO 接口,支持水、气表的脉 冲输入,非常适合综合能源管理系统使用。产品安装方便、接线方式灵 活,既适合新建设施的配电计量,也可用于已有配电系统改造。
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2010年考研英语(一)真题及答案解析

2010年考研英语(一)真题及答案解析

2010年考研英语(一)真题及答案解析2010年考研英语(一)真题及答案解析2010年考研英语(一)真题及答案解析Section I Use of EnglishDirections:Read the following text. Choose the best word(s) for each numbered blank and mark A, B, C or D on the ANSWER SHEET. (10 points)The idea that hard work is the key to success is nothing new.1,_____new research from psychologist Anders Ericsson and 2_____ colleagues suggests that practice is the magic number of greatness.Ericsson studies thousands of chess players, musicians, athletes and others. He 3_____ out the average number of training hours per week the people he studied 4_____ in _____ to reach world-class levels of performance. Across the board, 5_____ to the 10 years or 10,000 hours were required. 6_____, more recent research_____ out that the amount of practice time needed may vary in fields that____ many social or physical activities. 7_____, deliberate practice is the key ingredient for achieving______ results in any field.Deliberate practice is not just mindless repetition. It is a purposeful and thoughtful 8_____ that requires intense focus. 9_____have discovered that top performers spend less time in _____ practice compared to average performers, but their practice is so much more productive. They grow_____, receive constant feedback and continually 10_____ their performance.Achieving world-class performance, according to Ericsson, is not about talent or innate ability; it is all about deliberate practice.1. [A] But[B] Or [C] So [D] Yet2. [A] their[B] his [C] other [D] the3. [A] found [B] turned[C] checked[D] carried4. [A] took part [B] trained [C] relied [D] engaged5. [A] up to [B] for [C] in addition [D] by far6. [A] Consequently [B] Importantly[C] Additionally[D] Meanwhile7. [A] Although [B] Besides[C] However[D] Therefore8. [A] future[B] experience [C] exercise [D] performance9. [A] Workers [B] Researchers [C] Engineers [D] Scientists10. [A] evaluate[B] develop [C] explain [D] demonstrate解析:1. [A] But 是转折连词,与"hard work is the key to success"对立,而下文要说明practice才是成功的关键,所以应该选[A] But。

Engineered O-Rings Catalog ORD 5710 美国Parker O-Rin

Engineered O-Rings Catalog ORD 5710 美国Parker O-Rin

Engineered O-Rings Catalog ORD 5710 USASimple solutionsfor complex sealing problemsIn the O-Ring Division’s monitoring each step of the process Finite element analysisElement Analysistion process and ensures theselection of the right materialand geometry for a customer’sapplication. As an addedbenefit, FEAused to predict service life.a simple interfacespecific glands and seals. Itversions of these books, availableas ORD 5703 (US) and 5705(Europe), provide engineersfor static and dynamic seals,with world productionamounting tobillions per year.In 1937,Niels A. Christensen, aDanish emigrant to the USA,was awarded a patent for thisring with the perfectgeometricalshape.In 1949,Parker O-ring materialsled to the aeronautical specifica-tion MIL-P-5515 B and to the dimensionalstandards MS 29512 and 513, which werebased on Parker O-rings. Since then, theO-ring has become a vital sealingelement in all kinds of fluidpower equipment.advice from Parker sealing experts isnever far away.Parker O-Ring division’s manufacturing facilities span 4 continents and 9countries. Some of these The division’s North American headquarters, located in Lexington KY , isApplicationsTransportation•Brakes/ABS•Cooling/air conditioning •Fuel and diesel injection, spark plugs•Quick connects, couplings, gear units•Shock absorbers •Steering systems•Transmissions and radiator sealsAerospace•Aircraft engines, wheels and brakes•Control and actuation systems•Fuel systems•Space shuttle launch vehiclesMedical•Dyalizers•Syringes, infusions•USP Class VI and FDA “White Listed” formulations are availableSemiconductor Processing•For wet, dry and thermal processes•Parker UHP Processing:Parker uses totally enclosed and dedicated manufacturing areas for compounding,preparation, molding, cleaning and final packaging of o-rings in critical compounds for semiconductor processing applicationsFluid Power•Accumulators •Cylinders, valves •Filters •Fittings •Pumps•Rotary actuatorsConsumer Products•Appliances•Compounds meeting the requirements/recommen-dations: FDA, NSF, WRC,DVGW, BGA, KTW •Heating/plumbing •Sanitary equipmentChemical Processing Industry (CPI)•Equipment and components requiring extremely high chemical inertness attemperatures up to +320°CEnergy/Oil Field•Drilling•Exploration •Production •TransportationParker O-rings are used in many applications and industries, including:1-800-C-Parker Parker O-Ring Division Worldwide LocationsNorth AmericaUSAParker Hannifin CorporationO-Ring Division2360 Palumbo Drive Lexington, KY 40509 Phone: (859) 269-2351Fax: (859) 335-5128 Parker Hannifin CorporationO-Ring Division104 Hartmann Drive Lebanon, TN 37087Phone: (615) 444-0191Fax: (615) 449-7312 Parker Hannifin CorporationO-Ring Division109 Industrial Park Drive Livingston, TN 38570 CanadaParker Hannifin CorporationO-Ring Division255 Hughes RoadOrillia, Ontario L3V 2M3 Phone: (705) 325-2391Fax: (705) 325-5721 MexicoParker Hannifin CorporationO-Ring DivisionPSDM Business Unit Diagonal Lorenzo de la Garza #13 Ciudad IndustrialH. Matamoros, Tam. 87490 Parker Hannifin CorporationO-Ring DivisionBRCO Business UnitCalle Sexta Y Vizcaya #95 Col. EuzkadiH. Matamoros, Tam. 87370 EuropeAustriaSee GermanyBelgiumParker Hannifin SA NVParc Industriel Sud, Zone II 15, Rue du Bosquet1400 NivellesPhone:+(32) 67-28 09 00 Fax:+(32) 67-28 09 99 Czech RepublicParker Hannifin s.r.o. Podebradská 100528912 SadskáPhone: +(420) 325-55 5111 Fax: +(420) 325-55 5112 DenmarkPolar Seals A/S Bjergvangen 23060 EspergærdePhone: +(45) 49 12 17 00 Fax: +(45) 49 12 17 01FinlandParker Hannifin OyYlastontie 16FIN-01510 VantaaPhone: +(358) 9-47 67 31Fax: +(358) 9-47 67 32 00FranceParker Hannifin RakZ.l. du Mont-BlancB.P. 482, Ville-la-Grand74108 Annemasse-CédexPhone: +(33) 4-50 87 80 80Fax: +(33) 4-50 87 80 76GermanyParker Hannifin GmbHO-Ring DivisionStuifenstr. 55D-74385 PleidelsheimPhone:+(49) 71 44-206-0Fax: +(49) 71 44-2 37 49HungaryParker Hannifin CorporationBudapest Representation OfficeVezer u. 156-1581148 BudapestPhone: +(36) 1-2 52 81 37Fax: +(36) 1-2 52 81 29IrelandSee United KingdomItalyParker Seals S.p.A.Via Marzaghette 2I-25030, Adro (BS)Phone: +(39) 030 754 811Fax: +(39) 030 745 8210Parker Hannifin S.p.A.Via Priv. Archimede, 120094 Corsico (Mi)Phone: +(39) 02-4 51 92-1Fax: +(39) 02-4 47 93 40NetherlandsParker Hannifin B.V.Edisonstraat 1P.O. Box 3407570 AH OldenzaalPhone: +(31) 541-58 50 00Fax: +(31) 541-58 54 59NorwayParker Hannifin A/SBerghagenP.O. Box 3008N-1402 SkiPhone: +(47) 64 91 10 00Fax: +(47) 64 91 10 90PolandParker Hannifin Sp. z.o.o.ul. Parowcowa 8B02-445 WarsawPhone: +(48) 22-8 63 49 42/43Fax: +(48) 22-8 63 49 44RussiaParker Hannifin CorporationKomsomolsky Prospect 42Office 407119827 GSP Moscow G-48Phone: +(7) 095-234 0054Fax: +(7) 095-242 0907Slovakiasee Czech RepublicSwedenParker Hannifin Sweden ABBox 831416308 SpangaPhone: +(46) 8-7 60 29 60Fax: +(46) 8-7 61 81 70SwitzerlandSee GermanySpainParker Hannifin Espana S.A.Paseo Cordellas, 5708290 Cerdanyola-del-Valles(Barcelona)Phone: +(34) 93-6 91 50 62Fax: +(34) 93-6 91 46 19United KingdomParker Hannifin plcSeal GroupParkway, Globe ParkMarlow, Bucks SL7 1YBPhone: +(44) 16 28-40 40 88Fax: +(44) 16 28-40 40 89Asia PacificAustraliaParker Hannifin Australia Pty. Ltd.9 Carrington Road2154 (NSW) Castle HillPhone: +(61) 2-96 34 77 77Fax: +(61) 2-98 42 51 11ChinaParker HannifinFluid Power Systems(Shanghai) Co., Ltd.280 Yun Qiao RoadJian Qiao Export Processing ZoneShanghai 201206Phone: +(86) 21-5031 2525Fax: +(86) 21-5834 3714Parker Asun Sealing CompanyNo. 26 Tian Bao RoadTian Bao Industrial ZoneDong Guan CityGuang Dong, P.R.O.C.Hong KongParker Hannifin Hong Kong Ltd.8/F Kin Yip Plaza9 Cheung Y ee StreetCheung Sha Wan, KowloonPhone: +(852) 24 28 80 08Fax: +(852) 24 80 42 56JapanParker Hannifin Japan Ltd.Osaka Sales OfficeNo. 2 Tani Bldg.1-4-25, Nishi-Miyahara,Yodogawa-KuPhone: +(81) 6-48 07-32 88Fax: +(81) 6-48 07-32 99KoreaParker Hannifin Korea Ltd.902 Dae Heung Bldg.648-23 Yeaksam-dongKangnam-Ku, Seoul 135-080Phone: +(82) 2-5 61 04 14Fax: +(82) 2-5 56 81 87SingaporeParker Hannifin Singapore Pte., Ltd.No. 11 Fourth Chin Bee RoadJurong Town 61 9702Phone: +(65) 261 5233Fax: +(65) 265 5125TaiwanParker Hannifin Taiwan, Ltd.8F-1, No 102 Sung Lung RoadTaipeiPhone: +(886) 2 8787 3780Fax: +(886) 2 8787 3782AfricaParker Hannifin Africa Pty. Ltd.Parker Place10 Berne AvenueAeroportKempton Park, South AfricaPhone: +(27) 11-3 92 72 80Fax: +(27) 11-3 92 72 13Latin AmericaArgentinaParker Hannifin Argentina SAICStephenson 27111667 Tortuguitas - Malvinas Arg.Buenos AiresPhone: +(54) 1-1 47 52-41 29Fax: +(54) 1-1 47 52-37 04BrazilParker Hannifin do BrasilIndustria e Comercia Ltda.Via Anhanguera, Km 25,305275 Sao Paulo / SPPhone: +(55) 11-39 17-10 99Fax: +(55) 11-39 17-08 17Continental HeadquartersManufacturing plants1/2-2.5M-CE。

二学历2010一月cj-2010-1-rxl

二学历2010一月cj-2010-1-rxl

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鲍叶枫 鲍叶枫 鲍叶枫 张勇 王旭 葛赓 葛赓 葛赓 白林 王钟男 王莹 周飞 马佳磊 刘聪 岳龙 岳龙 王春蕊 王春蕊 苏超 苏超 苏超 郭晓宇 艾斌 黄碧蕾 赵孟茹 郭斯雯 商靖宇 孙宁 徐志华 徐志华 焦晶 姜凯元 姜凯元 孙蕾 孙蕾 朱智 杨淳 白杨 李健 李健 任冬雪 郭增才 樊宇 张国华 孙境泽 李佩直 李佩直 李佩直 郭超 李岩 李岩
陆叶 李冬冬 杜江 刘欢欢 刘欢欢 李婷婷 贺天夫 徐威 徐威 刘芃飞 石众 生云峰 周超 郑林凯 苏涵 周光宇 宫伟 张新达 张顺 唐成祥 唐成祥 王婧 孙野 王涛 王涛 王涛 魏学海 郑明镜 戴仁勇 刘天宇 张建成 徐学博 王天宏 姜皓 冯治邦 邵锋 单天慧 王耀萱 赵文录 孙珊珊 杜娜 郭蕴 吕杭江 刘卫华 赵袁博 曹伟 周文忠 陆熙丞 丁若阳 王琨 郭子黎
发电厂电气主系统 发电厂电气主系统 自动控制理论(二) 电工原理 自动控制理论(二) 电工原理 电力系统远动及调度自动化 电工原理 发电厂电气主系统 自动控制理论(二) 电工原理 自动控制理论(二) 电力系统远动及调度自动化 自动控制理论(二) 自动控制理论(二) 自动控制理论(二) 电力系统远动及调度自动化 电力系统分析 自动控制理论(二) 电力系统远动及调度自动化 自动控制理论(二) 电工原理 电力系统分析 电力系统远动及调度自动化 电工原理 自动控制理论(二) 自动控制理论(二) 电工原理 自动控制理论(二) 电工原理 自动控制理论(二) 电工原理 发电厂电气主系统 发电厂电气主系统 发电厂电气主系统 电力系统分析 自动控制理论(二) 电工原理 自动控制理论(二) 发电厂电气主系统 电工原理 电工原理 电工原理 电力系统分析 发电厂电气主系统 自动控制理论(二) 电工原理 发电厂电气主系统 电力系统分析 电工原理 发电厂电气主系统

瑞士RE-AL浮动刀柄

瑞士RE-AL浮动刀柄

Firmenprofil / Profil de l’entreprise / Company profile 公司介绍
4-5 6 6 7 8 8 9
10 11 12 - 13
14
15
Mit dem Ziel, eine zukunftweisende Marktnische auszufüllen, wurde 1963 die RE-AL gegründet. Unsere Unternehmung konzentriert sich auf die Entwicklung, Produktion und den weltweiten Vertrieb von Präzisions-Reibahlen und Hochleistungs-Pendelhalter.
Nano-composite precision coating for accurate reaming; the latest alternative to carbide reamers.
Neue Hartstoffbeschichtung / Nouveau revêtement à surface dure / New hard surface coating
RE-AL was founded in 1963 with the aim to fill a growing niche in the market. The company concentrate on the manufacture, development and worldwide distribution of precision reamers and top precision floating holders for high performance reaming.

2010意外保险

2010意外保险

2011.6-9减少
2011年3月9减少
2010.8.11减少
146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194
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2010年报价单

2010年报价单

3/8
广 州 登 勤 体 育 用 品 有 限 公 司 英 国 RSL(亚狮龙)中 国 总 代 理
型号
RB-714 RB-901 RB-902 RB-903 RB-904 RB-905 RB-906 Z020
品名
(拍包10支装) (小双肩背包) (大双肩背包) (两格球拍套) (三格球拍套) (小双肩背包) (小双肩背包) (单球拍丝绒袋) 35cm X 70cm(100%棉)+网格袋 45cm X 80cm(100%棉)+网格袋 70cm X 140cm(100%棉)+网格袋 30cm X 30cm(100%棉)+PE胶袋
Millennium 6
Nova 6190 Nova 6170 Nova 6160
Millennium 5
Heat Ti 5800
Millennium 4
Millennium Heat Ti 4900 4900 Millennium Super Ti 4300 4300 Millennium Super Ti 4200 4200 Millennium Power G 4010 4010 Millennium Power G 4030 4030 Millennium Power G 4070 4070 Millennium Power G 4080 4080 Millennium Power G 4090 4090
1/8
广 州 登 勤 体 育 用 品 有 限 公 司 英 国 RSL(亚狮龙)中 国 总 代 理
型号
RSL-Extreme 070 RSL-Extreme 050 Extreme 070 Extreme 050 9010 9020 9030 9070 9080 9090 9900 9600 9500 9180 9110 9100

Estimation-of-affine-term-structure-models-with-spanned-or-unspanned-stochastic-volatility

Estimation-of-affine-term-structure-models-with-spanned-or-unspanned-stochastic-volatility

∗ We thank Yacine Ait-Sahalia, Boragan Aruoba, Michael Bauer, Alan Bester, John Cochrane, Frank Diebold, Rob Engle, Jim Hamilton, Chris Hansen, Guido Kuersteiner, Ken Singleton, two anonymous referees, and seminar and conference participants at Chicago Booth, NYU Stern, NBER Summer Institute, Maryland, Bank of Canada, Kansas, UMass, and Chicago Booth Junior Finance Symposium for helpful comments. Drew Creal thanks the William Ladany Faculty Scholar Fund at the University of Chicago Booth School of Business for financial support. Cynthia Wu also gratefully acknowledges financial support from the IBM Faculty Research Fund at the University of Chicago Booth School of Business. This paper was formerly titled “Estimation of non-Gaussian affine term structure models.” Correspondence: dcreal@; cynthia.wu@.

2 百事特高尔夫2010产品报价-罗

2 百事特高尔夫2010产品报价-罗

1234产品图片型号T101T102T103T104品名磁性球钉(胶钉,75MM)磁性球钉(75MM)磁性球钉(75MM)双支装磁性球钉(胶钉)单位盒盒盒盒价格¥2.50¥2.50¥2.50¥5.00产品图片型号T107T108T109T110品名磁性球钉(80MM)磁性球钉(80MM)磁性球钉(胶钉,80MM)磁性球钉(80MM)单位盒盒盒盒价格¥2.50¥5.00¥2.50¥2.50产品图片型号T113T114T115T116品名复位磁性球钉(70MM)复位磁性球钉(70MM)复位磁性球钉(70MM)复位磁性球钉(70/80MM)单位盒盒盒盒价格¥2.70¥2.70¥2.70¥5.00产品图片型号T119T120T121T122地址:广东深圳市龙岗区平湖平龙公路巨志工业区腾成工业园3#厂房 电话:13670086百事特高尔夫用品报价单品名复位磁性球钉(83MM)复位磁性球钉(83MM)旋转球钉(70/80MM)旋转球钉(70/80MM)单位盒盒盒盒价格¥2.70¥3.50¥6.00¥6.00产品图片型号T125T126T127T128品名反弹母子球钉(80MM)反弹母子球钉(80MM)三支装反弹球钉(80MM)双支装反弹球钉(80MM)单位盒盒盒盒价格¥2.50¥2.50¥3.50¥4.50产品图片型号T131T132T133T134品名空气球钉(80MM)空气球钉(70/80MM)弹簧开花球钉(胶钉)弹簧球钉(70MM)单位盒盒盒盒价格¥3.00¥5.00¥2.00¥2.00产品图片型号T137T138T139T140品名弹簧球钉(80MM)弹簧球钉(80MM)三支装弹簧球钉(70/80MM)四支装弹簧球钉(80MM)单位盒盒盒盒价格¥2.00¥2.00¥3.50¥8.50产品图片型号T143T144T145T146品名弹簧开花球钉(80MM)弹簧开花球钉(80MM)新款开花球钉(70MM)新款开花球钉(80MM)单位盒盒盒盒价格¥3.50¥4.50¥2.00¥2.00产品图片型号T149T150T151T152品名橡胶球钉(80MM)橡胶球钉(80MM)记分球钉(80MM)记分球钉(80MM)单位盒盒盒盒价格¥2.50¥2.50¥3.00¥3.00产品图片型号T155T156T157T158品名皇冠球钉毛刷球钉(70/80MM)零阻力球钉铁杆球钉单位盒盒袋盒价格¥2.00¥4.50¥4.00¥3.00产品图片型号T161T162T163T164品名木钉(42/54/70/83MM)胶钉(42/54/70/84MM)限位木钉(42/54/70/83MM)限位胶钉(48/76/83MM)单位袋袋袋袋价格¥1.00¥1.00¥1.00¥1.00品名竹钉胶钉限位胶钉木钉单位个个个个价格 4.2CM:0.06 4.2CM:0.05 4.8CM:0.07 4.2CM:0.05价格 5.4CM:0.07 5.4CM:0.06 5.4CM:0.06价格7.0CM:0.087.0CM:0.077.0CM:0.07价格8.3CM:0.098.3CM:0.087.6CM:0.098.3CM:0.085.4CM:0.08产品图片型号C208C209C210C215品名五星红旗帽夹球包形帽夹帽夹帽夹单位袋盒袋袋价格¥6.00¥6.00¥10.00¥10.00型号C218C219C220C221品名花形品钻帽夹新款圆形水钻帽夹圆形水钻帽夹水平仪帽夹单位盒盒盒盒价格¥9.00¥9.00¥9.00¥5.00品名帽夹帽夹笑脸水钻帽夹圆形品牌帽夹单位袋袋盒盒价格¥10.00¥10.00¥10.00¥4.00产品图片型号品名新款三角复位磁性球钉小礼盒装水钻帽夹多功能帽夹帽夹单位盒盒盒袋价格¥2.50¥10.00¥10.00¥10.00产品图片型号D101D102D103D104品名锌合金果岭叉锌合金果岭叉锌合金果岭叉锌合金果岭叉单位个个个个价格¥12.00¥9.00¥7.00¥7.00产品图片型号D107D111D112D113品名锌合金果岭叉开瓶器果岭叉五金果岭叉五金果岭叉单位个个个个数量¥7.00¥4.00¥2.00¥1.50产品图片型号G101G102G103G104品名礼盒礼盒礼盒礼盒单位盒盒盒盒价格¥42.00¥23.00¥20.00¥17.00产品图片型号G107G108G109G111品名礼盒礼盒礼盒礼盒单位盒盒盒盒价格¥13.00¥8.00¥6.00¥45.00产品图片品名礼盒礼盒礼盒礼盒单位盒盒盒盒价格¥80.00¥100.00¥75.00¥70.00产品图片品名高尔夫笔筒高尔夫笔筒最新款发声挥杆练习棒小球包单位个个个个价格¥33.00¥42.00¥100.00¥20.00产品图片型号A101A102A103A104品名画球器画球器,捡球器球夹吸球器单位个盒个个价格¥5.00¥4.00¥3.50¥5.00产品图片型号A107A108A109A110品名球头扳手球夹画球器双面刷三用刷单位盒 盒把个价格¥8.00¥6.00¥6.00¥4.00产品图片型号A113品名圆头刷五用工具新款洒水刷盒装姿势纠正器单位个个把盒价格¥6.00¥6.00¥15.00¥9.00产品图片型号A115A116A117A118品名加重环木钉座推杆毯(30*300CM)推杆毯(60*300CM)单位个个个个价格¥4.00¥4.00¥100.00¥180.00产品图片型号A121A122A122A123品名捡球筒捞球器不锈钢捞球器高尔夫皮带(可伸缩)单位个3节:29元/个个盒4节:38元/个5节:42元/个6节:45元/个产品图片型号A125A126A127品名PU球空洞球无孔空心球高尔夫球展示架单位盒盒盒个价格¥9.00¥4.00¥4.00¥80.00价格¥35.00¥70.00¥39.00产品图片型号A129品名表形记分器鼠形记分器圆形记分器方形记分器单位个个个个价格¥5.00¥4.00¥12.00¥4.00产品图片型号A132品名自动回球器怪形记分器木质记分笔木质记分笔单位盒个支支价格¥28.00¥6.00¥0.25¥0.20产品图片品名室内练习网切杆练习网切杆练习网三面切杆练习网单位个个个个价格小:120元¥80.00¥90.00¥110.00价格中: 180元价格大:230元产品图片品名老款挥杆棒挥杆练习器(进口草)推杆盘推杆盘单位盒盒个个价格¥35.00¥70.00¥4.00¥4.00产品图片品名塑胶球位标(25MM)新款转钉器手套架鞋钉(金属螺丝18个装)单位个个个盒价格¥0.07¥7.00¥5.00¥21.00产品图片手臂姿势纠正器品名三角形气垫挥杆娇正器8字形气垫挥杆娇正器 曲譬纠正器单位个个个个价格¥80.00¥80.00¥40.00¥40.00产品图片品名鞋钉(金属螺丝18个装)鞋钉(三角卡扣,18个装)鞋钉(快速旋转,18个装)毛巾(41*53CM)单位盒盒盒条价格¥30.00¥30.00¥30.00¥14.00以上单从为RMB出厂价,不含运费和税56T105T106磁性球钉(胶钉,80MM)磁性球钉(80MM)盒盒¥2.50¥2.50T111T112四支装磁性球钉(80MM)四支装磁性球钉(80MM)盒盒¥10.00¥10.00T117T118复位磁性球钉(83MM)复位磁性球钉(83MM)盒盒¥2.70¥2.70T123T12473 联系人:罗小姐70086036 传真:0755-********价单三段球钉(48MM)三段球钉(48MM)盒盒¥6.00¥6.00T129T130空气球钉(70MM)空气球钉(80MM)盒盒¥3.00¥3.00T135T136龙凤弹簧球钉双支装弹簧球钉(70/80MM) (70/80MM)盒盒¥3.00¥4.00T141T142弹簧开花球钉(80MM)弹簧开花球钉(80MM)盒盒¥2.00¥2.00T147T148新款开花球钉(80MM)新款开花球钉(80MM)盒盒¥3.50¥4.00T153T154四支装橡胶球钉(80MM)软胶套球钉盒盒¥8.50¥2.00T159T160练习球钉竹钉(54/70/83MM)盒袋¥5.00¥1.00冬用球钉扁形球钉套个¥4.50¥0.12限位木钉胶钉个筒3.8CM:0.084.2CM:800个装:43元5.4CM:0.09 5.4CM:500个装:33元7.0CM:0.107.0CM:400个装:35元8.3CM:0.118.3CM:300个装:30元C216C217帽夹蝴蝶形水钻帽夹袋盒¥10.00¥9.00新款三角磁性球钉品牌帽夹盒盒¥5.00¥2.50笑脸帽夹高尔夫单层木质握把盒把¥4.00¥30.00球形水钻帽夹球头笔座礼盒盒套¥12.00¥60.00D105D106锌合金果岭叉锌合金果岭叉个个¥7.00¥7.00D115D116塑胶带刷果岭叉塑胶果岭叉个个¥1.00¥0.40G105G106礼盒礼盒盒盒¥10.00¥12.00礼盒礼盒盒盒¥50.00¥48.00高尔夫笔筒高尔夫笔筒个个¥26.00¥33.00小球包手婉固定器个盒¥8.00¥40.00A105A122-1手套架红色捡球器/新捡球器个个(5节)¥12.00(15尺/45元,6尺/36元)A111A112七用工具刷与叉个个¥5.00¥6.00A113A114姿势纠正器(散装)铁杆套(10个/盒)个盒¥6.00¥27.00A119A120风力练习器新款挥杆棒盒盒¥150.00¥60.00A123A124高尔夫皮带(不可伸缩)彩虹球盒盒A127A128高尔夫球展示架测距器个个¥80.00¥7.00¥75.00¥6.00A131小形记分器长方形记分器个个¥4.00¥7.00塑胶记分笔高尔夫记分珠支个¥0.20¥6.00塑胶推杆练习毯个把(握把是塑胶)30*300CM自动¥45.00¥135.00软胶推杆盘塑胶球位标(19MM)个个¥5.00¥0.04球擦亚克力球包牌个个¥5.007腿部纠正器3米红木推杆练习毯个个¥40.00¥180.00高尔夫帽子把 握把是水晶材质顶¥35.00¥20.00费和税.。

1008 2010 EU

1008 2010 EU

REGULATIONSCOMMISSION REGULATION (EU) No 1008/2010of 9 November 2010concerning type-approval requirements for windscreen wiper and washer systems of certain motorvehicles and implementing Regulation (EC) No 661/2009 of the European Parliament and of the Council concerning type-approval requirements for the general safety of motor vehicles, theirtrailers and systems, components and separate technical units intended therefor(Text with EEA relevance)THE EUROPEAN COMMISSION,Having regard to the Treaty on the Functioning of the European Union,Having regard to Regulation (EC) No 661/2009 of the European Parliament and of the Council of 13 July 2009 concerning type- approval requirements for the general safety of motor vehicles, their trailers and systems, components and separate technical units intended therefor ( 1 ), and in particular Article 14(1)(a) thereof, Whereas:(1) Regulation (EC) No 661/2009 is a separate Regulation for the purposes of the type-approval procedure provided for by Directive 2007/46/EC of the European Parliament and of the Council of 5 September 2007 establishing aframework for the approval of motor vehicles and theirtrailers, and of systems, components and separatetechnical units intended for such vehicles (Framework Directive) ( 2 ). (2) Regulation (EC) No 661/2009 repeals Council Directive78/318/EEC of 21 December 1977 on the approxi ­mation of the laws of the Member States relating tothe wiper and washer systems of motor vehicles ( 3 ).The requirements set out in that Directive should be carried over to this Regulation and, where necessary, amended in order to adapt them to the development of scientific and technical knowledge.(3) The scope of this Regulation should be in line with thatof Directive 78/318/EEC and thus limited to vehicles ofcategory M 1 .(4) Regulation (EC) No 661/2009 lays down fundamentalprovisions on requirements for the type-approval of motor vehicles with regard to their windscreen wiper and washer systems and the type-approval of windscreenwasher systems as separate technical units. Therefore, it is necessary to set out the specific procedures, tests and requirements for such type-approval.(5) Themeasures provided for in this Regulation are in accordance with the opinion of the Technical Committee – Motor Vehicles,HAS ADOPTED THIS REGULATION:Article 1 ScopeThis Regulation applies to motor vehicles of category M 1, as defined in Annex II to Directive 2007/46/EC, which are fittedwith a windscreen, as well as to windscreen washer systemsintended for fitment to motor vehicles of category M 1 . Article 2 DefinitionsFor the purposes of this Regulation, the following definitionsshall apply:(1) ‘vehicle type with regard to the windscreen wiper andwasher system’ means vehicles which do not differ in such essential respects as: the characteristics of the wiper and washer system or the shape, size and characteristics of the windscreen and its mounting; (2) ‘type of windscreen washer system’ means a group ofwindscreen washer systems which do not differ in such essential respects as the pump performance, materials used, storage capacity, number of nozzles, sizes, wall thicknesses or shape of the washer system; (3) ‘engine’ means a combustion engine running on eitherliquid or gaseous fuel; (4) ‘windscreen wiper system’ means the system consisting ofa device for wiping the outer face of the windscreen, together with the accessories and controls necessary for starting and stopping the device;( 1 ) OJ L 200, 31.7.2009, p. 1. ( 2 ) OJ L 263, 9.10.2007, p. 1. ( 3 ) OJ L 81, 28.3.1978, p. 49.(5) ‘wiper field’ means the area(s) on the windscreen which iswiped by the wiper blade(s) when the wiper system is operating under normal conditions.(6) ‘intermittent operation of the wiper system’ means anautomatic non-continuous mode of operation of the wiper system, where after each full cycle there is a period during which the wipers are stationary in one specific designated halting position;(7) ‘windscreen washer system’ means the system consisting ofdevices for storing, transferring and aiming fluid towards the outer face of the windscreen, together with the controls necessary for starting and stopping the device;(8) ‘washer control’ means the device by which the washersystem is manually activated and deactivated;(9) ‘washer pump’ means a device for transferring fluid fromthe washer system storage reservoir to the outer face of the windscreen;(10) ‘nozzle’ means a device which serves to direct fluid ontothe windscreen;(11) ‘fully primed system’ means a system which has beenactivated normally for a period of time and where fluid has been transferred through the pump, tubing and has exited the nozzle(s);(12) ‘cleaned area’ means the previously soiled area which doesnot have any traces of drops and remaining dirt after it hasdried completely;(13) ‘vision area A’ means test area A as defined in paragraph2.2. of Annex 18 to UNECE Regulation No 43 (1);(14) ‘vision area B’ means reduced test area B as defined inparagraph 2.4. of Annex 18 to UNECE Regulation No 43, without the exclusion of the area defined in paragraph 2.4.1. thereof;(15) ‘design torso angle’ means the angle measured between avertical line through the R-point or seating reference pointand the torso line in a position which corresponds to the design position of the seat-back as declared by the vehicle manufacturer;(16) ‘R-point’ or seating reference point means the design pointdefined by the vehicle manufacturer for each seating position with respect to the three-dimensional reference system;(17) ‘three-dimensional reference system’ means a reference gridwhich consists of a vertical longitudinal plane X-Z, a hori­zontal plane X-Y and a vertical transverse plane Y-Z in accordance with the provisions of Appendix 2 of Annex III to this Regulation; (18) ‘primary reference marks’ means holes, surfaces, marks orother identification signs on the vehicle body or chassis ofwhich the X, Y and Z coordinates within the three-dimen­sional reference grid are specified by the vehicle manu­facturer;(19) ‘vehicle master control switch’ means the device by whichthe vehicle's on-board electronics system is brought frombeing switched off, as is the case when a vehicle is parkedwithout the driver being present, to normal operationmode;Article 3EC type-approval of a vehicle with regard to its windscreen wiper and washer systems1. The manufacturer or his representative shall submit to the type-approval authority the application for EC type-approval of a vehicle with regard to its windscreen wiper and washer systems.2. The application shall be drawn up in accordance with the model of the information document set out in Part 1 of Annex I.3. If the relevant requirements set out in Annex III to this Regulation are met, the approval authority shall grant an EC type-approval and issue a type-approval number in accordance with the numbering system set out in Annex VII to Directive 2007/46/EC.A Member State may not assign the same number to another vehicle type.4. For the purposes of paragraph 3, the type-approval authority shall deliver an EC type-approval certificate establishedin accordance with the model set out in Part 2 of Annex I.Article 4EC separate technical unit type-approval of windscreenwasher systems1. The manufacturer or his representative shall submit to the type-approval authority the application for EC separate technical unit type-approval for a type of windscreen washer system.The application shall be drawn up in accordance with the model of the information document set out in Part 1 of Annex II.2. If the relevant requirements set out in Annex III to this Regulation are met, the approval authority shall grant an EC separate technical unit type-approval and issue a type-approval number in accordance with the numbering system set out in Annex VII to Directive 2007/46/EC.(1) OJ L 230, 31.8.2010, p. 119.A Member State may not assign the same number to another type of separate technical unit.3. For the purposes of paragraph 2, the type-approval authority shall deliver an EC type-approval certificate established in accordance with the model set out in Part 2 of Annex II.Article 5EC separate technical unit type-approval mark Every separate technical unit conforming to a type in respect of which EC separate technical unit type-approval has been granted pursuant to this Regulation shall bear an EC separate technical unit type-approval mark as set out in Part 3 of Annex II.Article 6Validity and extension of approvals granted underDirective 78/318/EECNational authorities shall permit the sale and entry into service of vehicles and separate technical units type-approved before the date referred to in Article 13(2) of Regulation (EC) No 661/2009, and continue to grant extension of approvals to those vehicles and separate technical units under the terms of Directive 78/318/EEC.Article 7Entry into forceThis Regulation shall enter into force on the twentieth day following that of its publication in the Official Journal of the European Union.This Regulation shall be binding in its entirety and directly applicable in all Member States. Done at Brussels, 9 November 2010.For the CommissionThe PresidentJosé Manuel BARROSOANNEX IAdministrative documents for EC type-approval of motor vehicles with regard to their windscreen wiper andwasher systemsPART 1Information documentMODELInformation document No … relating to the EC type-approval of a motor vehicle with regard to its windscreen wiper and washer systems.The following information shall be supplied in triplicate and include a list of contents. Any drawings shall be supplied in appropriate scale and in sufficient detail on size A4 or on a folder of A4 format. Photographs, if any, shall show sufficient detail.If the systems, components or separate technical units referred to in this information document have electronic controls, information concerning their performance shall be supplied.0. GENERAL......................................................................................................................................ofmanufacturer):name(trade0.1. Make..................................................................................................................................................................................................0.2. Type:(if...........................................................................................................................................available):0.2.1. Commercialname(s)0.3. Means of identification of type, if marked on the vehicle (b): .......................................................................................marking:..........................................................................................................................................................ofthat0.3.1. Locationvehicle(c): .................................................................................................................................................................of0.4. Category.......................................................................................................................................manufacturer:of0.5. Nameandaddressplant(s):.....................................................................................................................assemblyandof0.8. Name(s)address(es)(ifrepresentative..................................................................................manufacturer'sany):addresstheand0.9. NameofTHEVEHICLEOFCHARACTERISTICSCONSTRUCTION1. GENERALrepresentativevehicle:...............................................................................................aand/orof1.1. Photographsdrawings(k)3. POWERPLANTengine3.2. Internalcombustion(n): ................................. kW at .................................. min–1(manufacturer's declared value) powernet3.2.1.8. Maximumsystem3.2.5. Electricalvoltage:...................................................................................................................... V, positive/negative ground (1) 3.2.5.1. Rated3.2.5.2. Generator3.2.5.2.1. Type: ..................................................................................................................................................................................................3.2.5.2.2. Nominal output: ....................................................................................................................................................................VAmotor3.3. Electric3.3.1.1. Maximumoutput:................................................................................................................................................... k W hourly (V)3.3.1.2. Operatingvoltage:3.3.2. Battery3.3.2.3. Capacity:.......................................................................................................................................................... A h (Amp-hours)combinationmotoror3.4. Engine(1)yes/noelectricvehicle:3.4.1. Hybridcharging/notoff-vehiclecharging:off-vehicle(1)electricvehicle:of3.4.2. Categoryhybrid(battery,capacitor,flywheel/generator)device:the3.4.4. Descriptionofenergystorage3.4.4.5. Energy:..............................................................................................................................................................................................(for battery: voltage and capacity Ah in 2 h, for capacitor: J, ......................................................................................)(1)board/external/withouton3.4.4.6. Charger:(p)4. TRANSMISSIONkm/h)(q): ......................................................................................................................speed(in4.7. Maximumvehicledesign9. BODYWORKofconstruction:......................................................................................................................andmethods9.2. Materialsusedvision9.4. Fieldof9.4.1. Particulars of the primary reference marks in sufficient detail to enable them to be readily identified and theposition of each in relation to the others and to the R-point to be verified: .........................................................windowsother9.5. Windscreenand9.5.1. Windscreen................................................................................................................................................................................used:9.5.1.1. Materials...................................................................................................................................................................mounting:9.5.1.2. Methodof....................................................................................................................................................................inclination:9.5.1.3. Angleofnumber(s):........................................................................................................................................................... 9.5.1.4. Type-approvalfittedwithatogetherofanydescriptionbriefinandaccessoriesarethe9.5.1.5. Windscreenpositiontheywhichelectrical/electronic components involved: ............................................................................................................................systemwiper9.6. Windscreenordrawings):...........................................................................photographs9.6.1. Detailedtechnicaldescription(includingsystemwasher9.7. Windscreen9.7.1. Detailed technical description (including photographs or drawings) or, if approved as separate technical unit,type-approval number: .................................................................................................................................................................demisting9.8. Defrostingand...................................................................................................................................kWconsumption:electrical9.8.2. Maximumarrangement9.10. Interior9.10.3. Seats9.10.3.5. Coordinates or drawing of the R-point9.10.3.5.1. Driver's seat: .................................................................................................................................................................................... 9.10.3.6. Design torso angle9.10.3.6.1. Driver's seat: ....................................................................................................................................................................................Explanatory notes(1) Delete where not applicable.(b) If the means of identification of type contains characters not relevant to describe the vehicle, component or separatetechnical unit types covered by this information document, such characters shall be represented in the documentation by the symbol ‘?’ (e.g. ABC??123??).(c) Classified according to the definitions set out in Directive 2007/46/EC Part A of Annex II.(k) In the case of a vehicle that can run either on petrol, diesel, etc., or also in combination with another fuel, items shall be repeated. In the case of non-conventional engines and systems, particulars equivalent to those referred to here shall be supplied by the manufacturer.(n) Determined in accordance with the requirements of Council Directive 80/1269/EEC (OJ L 375, 31.12.1980, p. 46). (p) The specified particulars are to be given for any proposed variants.(q) With respect to trailers, maximum speed permitted by the manufacturer.EC type-approval certificateMODELFormat: A4 (210 × 297 mm)EC TYPE-APPROVAL CERTIFICATECommunication concerning:— EC type-approval (1)— extension of EC type-approval (1) — refusal of EC type-approval (1) — withdrawal of EC type-approval (1)9 > > > >> => > > > > ;of a type of vehicle with regard to its windscreen wiper and washer systemswith regard to Regulation (EU) No 1008/2010, as last amended by Regulation (EU) No .../ (1)EC type-approval number: ............................................................................................................................................................................... Reason for extension: ........................................................................................................................................................................................SECTION I0.1. Make (trade name of manufacturer): .................................................................................................................................................0.2. Type: ............................................................................................................................................................................................................0.2.1. Commercial name(s) (if available): ......................................................................................................................................................0.3. Means of identification of type, if marked on the vehicle (2): ..................................................................................................0.3.1. Location of that marking: .....................................................................................................................................................................0.4. Category of vehicle (3): ...........................................................................................................................................................................0.5. Name and address of manufacturer: ..................................................................................................................................................0.8. Name(s) and address(es) of assembly plant(s): ................................................................................................................................0.9. Name and address of the manufacturer's representative (if any): ............................................................................................SECTION II1. Additional information: see Addendum.2. Technical service responsible for carrying out the tests: ...................................................................................................................3. Date of test report: .........................................................................................................................................................................................4. Number of test report: ..................................................................................................................................................................................5. Remarks (if any): see Addendum.6. Place: ...................................................................................................................................................................................................................7. Date: ....................................................................................................................................................................................................................8. Signature: ........................................................................................................................................................................................................... Attachments: Information packageTest report(1) Delete where not applicable.(2) If the means of identification of type contains characters not relevant to describe the vehicle, component or separate technical unittypes covered by this information document, such characters shall be represented in the documentation by the symbol ‘?’ (e.g.ABC??123??).(3) As defined in Directive 2007/46/EC, Annex II, Section A.to EC type-approval certificate No …1. Additional information:1.1. Brief description of the vehicle type as regards its structure, dimensions, lines and constituent materials: .............................................................................................................................................................................................................................................1.2. Description of the method of operation of the wiper and washing systems: ........................................................................1.3. Detailed description of the wiper system (i.e. number of blades, blade lengths, wiper arm dimensions, etc.): ..........1.4. Detailed description of the washer system (i.e. number of nozzles, number of outlet ports per nozzle, washer pump,fluid storage container, washer line hoses and their mounting to pump and nozzles, etc.) .............................................1.5. Fluid storage capacity (litre): ....................................................................................................................................................................1.6. Maximum vehicle design speed (km/h): ...............................................................................................................................................2. Hand of drive: left/right (1)3. Left hand drive and mirror-opposite right hand drive systems: yes/no (1)4. Aerodynamic spoiler fitted onto the wiper arm/wiper blade (1) at driver side/centre/passenger side/ (1)5. Remarks: .........................................................................................................................................................................................................(1) Delete as appropriate.ANNEX IIAdministrative documents for EC type-approval of windscreen washer systems as separate technical unitsPART 1Information documentMODELInformation document No … relating to the EC type-approval as a separate technical unit of windscreen washer systems.The following information shall be supplied in triplicate and include a list of contents. Any drawings shall be supplied in appropriate scale and in sufficient detail on size A4 or on a folder of A4 format. Photographs, if any, shall show sufficient detail.If the systems, components or separate technical units referred to in this information document have electronic controls, information concerning their performance shall be supplied.0. GENERAL0.1. Make (trade name of manufacturer): .................................................................................................................................................0.2. Type: ............................................................................................................................................................................................................0.3. Means of identification of type, if marked on the separate technical unit (b): ....................................................................0.3.1. Location of that marking: .....................................................................................................................................................................0.5. Name and address of manufacturer: ..................................................................................................................................................0.7. In case of separate technical units, location and method of affixing the EC approval mark: .......................................0.8. Name(s) and address(es) of assembly plant(s): ................................................................................................................................0.9. Name and address of the manufacturer's representative (if any): ............................................................................................9.7. Windscreen washer9.7.1. Detailed technical description (including photographs or drawings): .....................................................................................Explanatory notes(b) If the means of identification of type contains characters not relevant to describe the vehicle, component or separatetechnical unit types covered by this information document, such characters shall be represented in the documentation by the symbol ‘?’ (e.g. ABC??123??).EC type-approval certificateMODELFormat: A4 (210 × 297 mm)EC TYPE-APPROVAL CERTIFICATECommunication concerning:— EC type-approval (1)— extension of EC type-approval (1) — refusal of EC type-approval (1) — withdrawal of EC type-approval (1)9 > > > >> => > > > > ;of a type of windscreen washer system as a separate technical unitwith regard to Regulation (EU) No 1008/2010, as last amended by Regulation (EU) No .../ (1)EC type-approval number: ............................................................................................................................................................................... Reason for extension: ........................................................................................................................................................................................SECTION I0.1. Make (trade name of manufacturer): .................................................................................................................................................0.2. Type: ............................................................................................................................................................................................................0.3. Means of identification of type, if marked on the separate technical unit (2): ....................................................................0.3.1. Location of that marking: .....................................................................................................................................................................0.5. Name and address of manufacturer: ..................................................................................................................................................0.7. Location and method of affixing of the EC approval mark: ....................................................................................................0.8. Name(s) and address(es) of assembly plant(s): ................................................................................................................................0.9. Name and address of the manufacturer's representative (if any): ............................................................................................SECTION II1. Additional information: see Addendum.2. Technical service responsible for carrying out the tests: ...................................................................................................................3. Date of test report: .........................................................................................................................................................................................4. Number of test report: ..................................................................................................................................................................................5. Remarks (if any): see Addendum.6. Place: ...................................................................................................................................................................................................................7. Date: ....................................................................................................................................................................................................................8. Signature: ........................................................................................................................................................................................................... Attachments: Information packageTest report(1) Delete where not applicable.(2) If the means of identification of type contains characters not relevant to describe the vehicle, component or separate technical unittypes covered by this information document, such characters shall be represented in the documentation by the symbol ‘?’ (e.g.ABC??123??).。

2010年考研英语真题

2010年考研英语真题

2010年考研英语真题2010年考研英语一试题Section I Use of EnglishDirections:Read the following text. Choose the best word(s) for each numbered blank and mark [A], [B], [C] or [D] on ANSWER SHEET 1. (10 points)In 1924 American’ National Research Council sent to engineer s to supervise a series of industrial experiments at a large telephone-parts factory called the Hawthorne Plant near Chicago. It hoped they would learn how stop-floor lignting__1__workers productivity. Instead, the studies ended __2___giving their name to the “Hawthorne effect”, the extremely influential idea that the very___3____to being experimented upon changed subjects’ behavior.The idea arose because of the __4____behavior of the women in the Hawthorne plant. According to __5____of the experiments, their hourly output rose when lighting was increased, but also when it was dimmed. It did not __6____what was done in the experiment; ___7_someting waschanged ,productivity rose. A(n)___8___that they were being experimented upon seemed to be____9___to alte r workers’ behavior ____10____itself.After several decades, the same data were _11__ to econometric the analysis. Hawthorne experiments has another surprise store _12 __the descriptions on record, no systematic _13__ was found that levels of productivity were related to changes in lighting.It turns out that peculiar way of conducting the experiments may be have let to__ 14__ interpretation of what happed.__ 15___ , lighting was always changed on a Sunday .When work started again on Monday, output __16___ rose compared with the previous Saturday and__ 17 __to rise for the next couple of days.__ 18__ , a comparison with data for weeks when there was no experimentation showed that output always went up on Monday, workers__ 19__ to be diligent for the first few days of the week in any case , before __20 __a plateau and then slackening off. This suggests that the alleged” Hawthorne effect “ is hard to pin down.1. [A] affected [B] achieved [C] extracted [D] restored2. [A] at [B]up [C] with [D] off3. [A]truth [B]sight [C] act [D] proof4. [A] controversial [B] perplexing [C]mischievous [D] ambiguous5. [A]requirements [B]explanations [C] accounts [D] assessments6. [A] conclude [B] matter [C] indicate [D] work7. [A] as far as [B] for fear that [C] in case that [D] so long as8. [A] awareness [B] expectation [C] sentiment [D] illusion9. [A] suitable [B] excessive [C] enough [D] abundant10. [A] about [B] for [C] on [D] by11. [A] compared [B]shown [C] subjected [D] conveyed12. [A] contrary to [B] consistent with [C] parallel with [D] pealliar to13. [A] evidence [B]guidance [C]implication [D]source14. [A] disputable [B]enlightening [C]reliable [D]misleading15. [A] In contrast [B] For example [C] In consequence [D] As usual16. [A] duly [B]accidentally [C] unpredictably [D] suddenly17. [A]failed [B]ceased [C]started [D]continued20. [A]breaking [B]climbing [C]surpassing [D]hitingSection II Reading ComprehensionPart ADirections:Read the following four texts. Answer the questions below each text by choosing [A], [B], [C] or [D]. Mark your answers on ANSWER SHEET 1. (40 points)Text 1Of all the changes that have taken place in English-language newspapers during the past quarter-century, perhaps the m ost far-reaching has been the inexorable decline in the scope and seriousness of their arts coverage.It is difficult to the point of impossibility for the average reader under the age of forty to imagine a time when high-quality arts criticism could be found in most big-city newspapers. Yet a considerable number of the most significant c ollections of criticism published in the 20th century consisted in large part of new spaper reviews. To read such bookstoday is to marvel at the fact that their learned contents were once deemed suitable for publication in general-circulation dailies.We are even farther rem oved from the unfocused newspaper review spublished in England between the turn of t he 2 0th century and the eve of World War Ⅱ, at a time when newsprint was dirt-cheap and stylish arts crit icism was consi dered an ornament to the publications in which it appe ared. In those far-off days, it was taken for granted tha t the cri tics of major papers woul dwri te in detail and at length about the events they covered. Theirs was a serious business, and even those reviewers who wore their learning lightly, like George Bern ard Shaw and Ernest Newman, could be trus ted to know what they were a bout. These men believed in journalism as a calling, and were proud to be published in the da ily press. “So few authors have brains enough or literary gift enough to keep their own end up in journalism, ”Newman wrote, “ that I am tempted to define‘journalism’ as ‘a term of cont empt appl ied by writers who are not read to writers who are’. ”Unfortunately, these critics are virtually forgotten. Neville Cardus, who wrote for the Manchester Guardian from 1917 until shortly before his death in 1975, is now known solely as a writer of essays ont he game of cricket. During his l ifetime, though, he was also one of England's foremost classical-music critics, and a stylist so widely admired that his Autobiography(1947)became a best-seller. He was knighted in 1967, the first music critic to be so ho nored. Yet on ly one of his books is now in print, and his vast body of writings on music is unknown save to specialists.Is there any chance that Cardus’s criticism will enjoy a revi val? The prospect seems remote. Jour nalistic tastes had changed long before his death, and postmodern readershave little use for the ric hly upholstered Vicwardian prose in which he specialized. Moreover, the amateur tradition in music criticism has been in headlong retreat.21. It is indicated in Paragraphs 1 and 2 that[A] arts criticism has disappeared from big-city newspapers.[B] English-language newspapers used to carry more arts reviews.[C] high-quality newspapers retain a large body of readers.[D] young readers doubt the suitability of criticism on dailies.22. Newspaper reviews in England before worl d warⅡwere characterized by[A] free themes.[B] casual style.[C] elaborate layout.[D] radical viewpoints.23. which of the following would Shaw and Newman most probably agree on?[A] It is writers’ duty to fulfill journalistic goals.[B] It is contemptible for writers to be journalists.[C] Writers are likely to be tempted into journalism.[D] Not all writers are capable of journalistic writing.24. What can be learned about Cardus according to the last two paragraphs?[A] His music criticism may not appeal to readers today.[B] His reputation as a music critic has long been in dispute.[C]His style caters largely to modern specialists.[D]His writings fail to follow the amateur tradition.25. What would be the best title for the text?[A] Newspapers of the Good Old Days.[B] The lost Horizon in Newspapers.[C] Mournful Decline of Journalism.[D] Prominent Critics in Memory.Text 2Over the past decade, thousands of patents have been granted for what are called business methods. received one for its “one-click” online payment system. Merrill Lynch got legal protection for an asset allocation strategy. One inventor patented a technique for lifting a box.Now the nation’s top patent court appears completely ready to scale back on business-method patents, which have been controversial ever since they were first authorized 10 years ago. In a move that has intellectual-property lawyers abuzz the U.S. court of Appeals for the federal circuit said it would use a particular case to conduct a broad review of business-method patents. In re Bilski , as the case is known , is “a very big deal”, says Dennis’D. Crouch of the University of Missouri School of law. It “has the potential to eliminate an entire class of patents.”Curbs on business-method claims would be a dramatic about-face, because it was the federal circuit itself that introduced such patents with is 1998 decision in the so-called state Street Bank case, approving a patent on a way of pooling mutual-fund assets. That ruling produced an explosion in business-method patent filings, initially by emerging internet companies trying to stake out exclusive pinhts to specific types of online transactions. Later, move established companies raced to add such patents to their files, if only as a defensive move against rivals that might beat them to the punch. In 2005, IBM noted in a court filing that it had been issued more than 300 business-method patents despite the fact that it questioned the legal basis for granting them. Similarly, some Wall Street investment films armed themselves with patents for financial products, even as they took positions in court cases opposing the practice.The Bilski case involves a claimed patent on a method for hedging risk in the energy market. The Federal circuit issued an unusual order stating that the case would be heard by all 12 of the court’s judges, rather than a typical panel of three, and that one issue it wants to evaluate is whether it should” reconsider” its state street Bank ruling.The Federal Circuit’s action come s in the wake of a series of recent decisions by the supreme Count that has narrowed the scope of protections for patent holders. Last April, for example the justices signaled that too many patents were being upheld for “inventions” that are obvious. The j udges on the Federal circuit are “reacting to the anti_ patent trend at the supreme court” ,says Harole C.wegner, a partend attorney and professor at aeorge Washington University Law School.26. Business-method patents have recently aroused concern because of[A] their limited value to business[B] their connection with asset allocation[C] the possible restriction on their granting[D] the controversy over authorization27. Which of the following is true of the Bilski case?[A] Its ruling complies with the court decisions[B] It involves a very big business transaction[C] It has been dismissed by the Federal Circuit[D] It may change the legal practices in the U.S.28. The word “about-face” (Line 1, Paro 3) most probably means[A] loss of good will[B] increase of hostility[C] change of attitude[D] enhancement of dignity29. We learn from the last two paragraphs that business-method patents[A] are immune to legal challenges[B] are often unnecessarily issued[C] lower the esteem for patent holders[D] increase the incidence of risks30. Which of the following would be the subject of the text?[A] A looming threat to business-method patents[B] Protection for business-method patent holders[C] A legal case regarding business-method patents[D] A prevailing trend against business-method patentsText 3In his book The Tipping Point, Malcolm Aladuell argues that social epidemics are driven in large part by the acting of a tiny minority of special individuals, often called influentials, who are unusually informed, persuasive, or well-connected. The idea is intuitively compelling, but it doesn’t explain how ideas actually spread.The supposed importance of influentials derives from a plausible sounding but largely untested theory called the “two step flow of communication”: Information flows from the media to the influentials and from them to everyone else. Marketers have embraced the two-step flow because it suggests that if they can just find and influence the influentials, those selected people will do most of the work for them. The theory also seems to explain the sudden and unexpected popularity of certain looks, brands, or neighborhoods. In many such cases, a cursory search for causes finds that some small group of people was wearing, promoting, or developing whatever it is before anyone else paid attention. Anecdotal evidence of this kind fits nicely with the idea that only certain special people can drive trendsIn their recent work, however, some researchers have come up with the finding that influentials have far less impact on social epidemics than is generally supposed. In fact, they don’t seem to be required of all.The researchers’ argument stems from a simple observing about social influence, with the exception of a few celebrities like Oprah Winfrey-whose outsize presence is primarily a function of media, not interpersonal, influence-even the most influential members of a population simply don’t interact with that many others. Yet it is precisely these non-celebrity influentials who, according to the two-step-flow theory, are supposed to drive social epidemics by influencing their friends and colleagues directly. For a social epidemic to occur, however, each person so affected, must then influence his or her own acquaintances, who must in turn influence theirs, and so on; and just how many others pay attention to each of these people has little to do with the initial influential. If people in the network just two degrees removed from the initial influential prove resistant, for example from the initial influential prove resistant, for example the cascade of change won’t propagate very far or affect many people.Building on the basic truth about interpersonal influence, the researchers studied the dynamics of populations manipulating a number of variables relating of populations, manipulating a number of variables relating to people’s ability to influence others and their tendency to be influenced. Our work shows that the principal requirement for what we call “global cascades”- the widespread propagation of influence through networks - is the presence not of a few influentials but, rather, of a critical mass of easily influenced people, each of whom adopts, say, a look or a brand after being exposed to a single adopting neighbor. Regardless of how influential an individual is locally, he or she can exert global influence only if this critical mass is available to propagate a chain reaction.31.By citing the book The Tipping Point, the author intends to[A]analyze the consequences of social epidemics[B]disc uss influentials’ function in spreading ideas[C]exemplify people’s intuitive response to social epidemics[D]describe the essential characteristics of influentials.32.The author suggests that the “two-step-flow theory”[A]serves as a solution to marketing problems[B]has helped explain certain prevalent trends[C]has won support from influentials[D]requires solid evidence for its validity33.what the researchers have observed recently shows that[A] the power of influence goes with social interactions[B] interpersonal links can be enhanced through the media[C] influentials have more channels to reach the public[D] most celebrities enjoy wide media attention34.The underlined phrase “these people” in paragraph 4 refers to the ones who[A] stay outside the network of social influence[B] have little contact with the source of influence[C] are influenced and then influence others[D] are influenced by the initial influential35.what is the essential element in the dynamics of social influence?[A]The eagerness to be accepted[B]The impulse to influence others[C]The readiness to be influenced[D]The inclination to rely on othersText 4Bankers have been blaming themselves for their troubles in public. Behind the scenes, they have been taking aim at someone else: the accounting standard-setters. Their rules, moan the banks, have forced them to report enormous losses, and it’s just not fair. These rules say they must value some assets at the price a third party would pay, not the price managers and regulators would like them to fetch.Unfortunately, banks’ lobbying now seems to be working. The details may be unknowable, but the independence of standard-setters, essential to the proper functioning of capital markets, is being compromised. And, unless banks carry toxic assets at prices that attract buyers, reviving the banking system will be difficult.After a bruising encounter with Congress, America’s Financial Accounting Standards Board (FASB) rushed through rule changes. These gave banks more freedom to use models to value illiquid assets and more flexibility in recognizing losses on long-term assets in their income statement. Bob Herz, the FASB’s chairman, cried out against those who “question our motives.” Yet bank shares rose and the changes enhance what on e lobby group politely calls “the use of judgment by management.”European ministers instantly demanded that the International Accounting Standards Board (IASB) do likewise. The IASB says it does not want to act without overall planning, but the pressure to fold when it completes it reconstruction of rules later this year is strong. Charlie McCreevy, a European commissioner, warned the IASB that it did “not live in a political vacuum” but “in the real word” and that Europe could yet develop different rules.It was banks that were on the wrong planet, with accounts that vastly overvalued assets. Today they argue that market prices overstate losses, because they largely reflect the temporary illiquidity of markets, not the likely extent of bad debts. The truth will not be known for years. But bank’s shares trade below their book value, suggesting that investors are skeptical. And dead markets partly reflect the paralysis of banks which will not sell assets for fear of booking losses, yet are reluctant to buy all those supposed bargains.To get the system working again, losses must be recognized and dealt with. America’s new plan to buy up toxic assets will not work unless banks mark assets to levels which buyers find attractive. Successful markets require independent and even combative standard-setters. The FASB and IASB have been exactly that, cleaning up rules on stock options and pensions, for example, against hostility form special interests. But by giving in to critics now they are inviting pressure to make more concessions.36. Bankers complained that they were forced to[A] follow unfavorable asset evaluation rules[B]collect payments from third parties[C]cooperate with the price managers[D]reevaluate some of their assets.37.According to the author , the rule changes of the FASB may result in[A]the diminishing role of management[B]the revival of the banking system[C]the banks’ long-term asset losses[D]the weakening of its independence38.According to Paragraph 4, McCreevy objects to the IASB’s attempt to[A]keep away from political influences.[B]evade the pressure from their peers.[C]act on their own in rule-setting.[D]take gradual measures in reform.39.The author thinks the banks were “on the wrong planet ”in that they[A]misinterpreted market price indicators[B]exaggerated the real value of their assets[C]neglected the likely existence of bad debts.[D]denied booking losses in their sale of assets.40.The author’s attitude towards standard-setters is one of[A]satisfaction.[B]skepticism.[C]objectiveness[D]sympathyPart BDirections:For Questions 41-45, choose the most suitable paragraphs from the list A-G and fill them into the numbered boxes to form a coherent text. Paragraph E has been correctly placed. There is one paragraph which dose not fit in with the text. Mark your answers on ANSWER SHEET1. (10 points)[A] The first and more important is the consumer’s growing preference for eating out; the consumption of food and drink in places other than homes has risen from about 32 percent of total consumption in 1995 to 35 percent in 2000 and is expected to approach 38 percent by 2005. This development is boosting wholesale demand from the food service segment by 4 to 5 percent a year across Europe, compared with growth in retail demand of 1 to 2 percent. Meanwhile, as the recession is looming large, people are getting anxious. They tend to keep a tighter hold on their purse and consider eating at home a realistic alternative.[B] Retail sales of food and drink in Europe’s largest markets are at a standstill, leaving European grocery retailers hungry for opportunities to grow. Most leading retailers have already tried e-commerce, with limited success, and expansion abroad. But almost all have ignored the big, profitable opportunity in their own backyard: the wholesale food and drink trade, which appears to be just the kind of market retailers need.[C] Will such variations bring about a change in the overall structure of the food and drink market? Definitely not. The functioning of the market is based on flexible trends dominated by potential buyers. In other words, it is up to the buyer, rather than the seller, to decide what to buy .At any rate, this change will ultimately be acclaimed by an ever-growing number of both domestic and international consumers, regardless of how long the current consumer pattern will take hold.[D] All in all, this clearly seems to be a market in which big retailers could profitably apply their scale, existing infrastructure and proven skills in the management of product ranges, logistics, and marketing intelligence. Retailers that master the intricacies of wholesaling in Europe may well expect to rake in substantial profits thereby. At least, that is how it looks as a whole. Closer inspection reveals important differences among the biggest national markets, especially in their customer segments and wholesale structures, as well as the competitive dynamics of individual food and drink categories. Big retailers must understand these differences before they can identify the segments of European wholesaling in which their particular abilities might unseat smaller but entrenched competitors. New skills and unfamiliar business models are needed too.[E] Despite variations in detail, wholesale markets in the countries that have been closely examined-France, Germany, Italy, and Spain-are made out of the same building blocks. Demand comes mainly from two sources: independent mom-and-pop grocery stores which, unlike large retail chains, are two small to buy straight from producers, and food service operators that cater to consumers when they don’t eat at home. Such food service operators range from snack machines to large institutional catering ventures, but most of these businesses are known in the trade as “horeca”: hotels, restaur ants, and cafes. Overall, Europe’s wholesale market for food and drink is growing at the same sluggish pace as the retail market, but the figures, when added together, mask two opposing trends.[F] For example, wholesale food and drink sales come to $268 billion in France, Germany, Italy, Spain, and the United Kingdom in 2000-more than 40 percent of retail sales. Moreover, average overall margins are higher in wholesale than in retail; wholesale demand from the food service sector is growing quickly as more Europeans eat out more often; and changes in the competitive dynamics of this fragmented industry are at last making it feasible for wholesalers to consolidate.[G] However, none of these requirements should deter large retailers (and even some large good producers and existing wholesalers) from trying their hand, for those that master the intricacies of wholesaling in Europe stand to reap considerable gains.Part CDirections:Read the following text carefullyand then translate the underlined segments into Chinese. Your translation should bewritten clearly on ANSWER SHEET 2. (10 points)One basic weakness in a conservation system based wholly on econom ic motives is that most members of the land community have no economic value. Yet these creatures are members of the biotic community and, if its stability depends on its integrity, they are entitled to continuance.When one of these noneconomic categories is threatened and, if we happen to love it, we invent excuses to give it economic importance. At the beginning of the century songbirds were supposed to be disappearing.(46)Scientists ju mped to the rescue with some distinctly shaky evidence to the effect that insects would eat us up if birds failed to control them. The evidence had to be economic in order to be valid.It is painful to read these roundabout accounts today. We have no land ethic yet, (47) but we have at least drawn nearer the point of adm itting that birds should continue as a matter of intrinsic right, regardless of the presence or absence of economic advantage to us.A parallel situation exists in respect of predatory mammals and fish-eatingbirds. (48) Time was when biologists som ewhat overworked the evidence that these creatures preserve the health of game by killing the physically weak, or that they prey only on “worthless” species. Here again, the evidence had to be economic in order to be valid. It is only in recent years that we hear the more honest argumentthat predators are members of the community, and that no special interest has the right to exte rminate the m f or the sake of a benefit, real or fancied, to itself.Some species of tree have been“read out of the party” by economics-minded foresters because they grow too slowly, or have too low a sale value to pay as timber crops.(49) In Europe, where forestry is ecologically more advanced, the noncommercial tree species are recognized as members of native forest community, to be preserved as such, within reason. Moreover, some have been found to have a valuable function in building up soil fertility. The interdependence of the forest and its constit uent tree species, ground flora, and fauna is taken for granted.To sum up: a systemof conservation based solely on economic self-interest is hopelessly lopsided. (50) It tends to ignore , and thus eventually to eliminate, many elements in the land community that lack commercial value,but that are essential to its healthyfunctioning. It assumes, falsely, that the economic parts of the biotic clock will function without the uneconomic parts.Section I: Use of English (10 points)Section II: Reading Comprehension (60 points)Part A (40 points)Part B (10 points)Part C (10 points)46 . 科学家们赶紧拿出某些明显站不住脚的证据来补救,大致说的是如果鸟儿不能控制昆虫数量的话,昆虫就会把我们吃光。

Is locked by the absorber

Is locked by the absorber

专利名称:Is locked by the absorber 发明人:青木 晋一,銭本 陽一,松岡 徹申请号:JP2004259359申请日:20040907公开号:JP4488844B2公开日:20100623专利内容由知识产权出版社提供摘要:PROBLEM TO BE SOLVED: To provide a disk player apparatus of a slot-in system in which a dumper can simply and surely be fitted.SOLUTION: The disk player apparatus is constituted so that a floating chassis 21 having a disk playing part in a player main body part 20 is elastically supported by a plurality of dumpers. An upper part case 200a is attached to an upper part of the main body part 20 and a lower part case 200b is attached to a lower part of the main body part 20, an outer frame part of the dumper 40 is attached to the main body part 20, an engagement part 211 to be engaged with the outer frame part of the dumper 40 is provided at the lower part case 200, and the outer frame part of the dumper 40 is inserted in this engagement part 211.COPYRIGHT: (C)2006,JPO&NCIPI申请人:三洋電機株式会社,三洋電機コンシューマエレクトロニクス株式会社地址:大阪府守口市京阪本通2丁目5番5号,鳥取県鳥取市立川町七丁目101番地国籍:JP,JP代理人:▲角▼谷 浩更多信息请下载全文后查看。

Benjamin Leroux Gevrey-Chambertin 1er Cru Champeaux

Benjamin Leroux Gevrey-Chambertin 1er Cru Champeaux

2010 Gevrey-Chambertin, Les Champeaux, 1er Cru, Benjamin LerouxProduct:10670Maturity:Drink 2016-2022 (For laying down)Vintage:2010Origin:France»Burgundy»Côte de Nuits»Gevrey ChambertinProducer:Benjamin LerouxGrape Variety:Pinot NoirStyle:Medium Bodied, Dry, 13% alcoholBerrys' NotesNew for 2010, the nose of this Gevrey-Chambertin wine glows with red fruit and shows a seamless texture on the palate. Suave and elegant with a touch of cherry, fresh minerals complete a fine finish. Drink 2016-2022.Jasper Morris MW, Berrys' Burgundy DirectorBenjamin Leroux has managed to produce almost as much wine in 2010 as he did in 2009. Some of his grape contracts were short because of the low crop in 2010, but he has been able to compensate with some new sources of supply. 2010, Benjamin’s fourth vintage, looks to be a great success in both colours here. Included in this selection is a cuvée of Volnay Santenots from the Hospices de Beaune whose élévage we entrusted to Benjamin.Property:Benjamin LerouxHaving created a name for himself as régisseur (general manager) of Domaine du Comte Armand in Pommard,Benjamin Leroux established, with English backing, a small négociant business based in Beaune since 2007. The range is confined to the Côte d’Or, from Chassagne-Montrachet to Gevrey-Chambertin, with the intention of developing farming contracts or indeed purchasing vineyards in the future.The possibilities are very exciting for this exceptionally talented vigneron. Benjamin is a master at delivering purity of fruit alongside a seamless texture in his wines which have only the subtlest influence of oak. One of Benjamin’s favourite locations for white wine vineyards is the border between Auxey-Duresses and Meursault, which is where Les Vireuils can be found. Here the natural weight of Meursault is enhanced by the fresher minerality typical of the side valley of Auxey-Duresses.Vintage Notes:2010 - Red BurgundyRed WinesThe red Burgundy wines are built around a triangle of fruit, tannins and acidity this year, whereas some Burgundian vintages lean more towards the tannic or the acidic. These are beautifully balanced wines in2010, very classical,with much more red fruit than black, notably cherries and raspberries, and very few green notes.They range from lighter to medium-full bodied depending on the extraction choices made by the producer. The major villages of the Côte de Beaune have fared as well as the Côte de Nuits. No other vintage is directly comparable but the purity and fresh finish of2002plus the density (and alas scarcity) of 1991 come to mind. There is huge pleasure in store for the Burgundy lover.Read here the 2009Vintage Report on White Burgundy wines.OverviewThere was no hype for 2010 Burgundy at the time of the vintage (unlike Bordeaux) but the wines which have just been bottled, or soon will be, have turned out to be something special. The reasons for this emerge in the next paragraphs.The tricky bit this year is that yields are way down, typically by 30% to 50%. Despite this, the majority of producers have maintained their 2009 prices with only those who want to reposition looking for a significant increase.WeatherThe first date of crucial importance was 19th December 2009, just as delegates were leaving the Copenhagen Climate Change conference, when temperatures plunged to record lows in a very short space of time. The Côte de Nuits was the worst affected, especially in those low lying vineyards where cold air can be trapped on humid soils and large patches failed to burst into leaf when spring eventually came.This winter freeze may well have reduced the crop for the great majority of vines which did survive, while a latish flowering in poor weather certainly did so. Everybody reported widespread millerandage, when bunches produce a large proportion of much smaller berries. Clearly the harvest would be short, and this was crucial because the subsequent poor summer could never have ripened a 2009 sized crop, while the small berries with a high skin to juice ratio could produce concentrated wines.The first half of July was exceptionally hot and dry, but the weather weakened in the second half of the month and August never really happened. The good news was that there was relatively little evidence of oidium, mildew or rot – but clearly the weather needed to cheer up significantly in September. However there was one more nasty surprise to come.A massive thunder storm took place on Sunday 12th September and included hail which ravaged the Santenay and Chassagne-Montrachet border. The electricity in the air also had an effect on nearly ripe white grapes, turning them brown or even blue overnight. Then Burgundy’s old friend, the north wind, came to the rescue and dried out the vineyards, preventing rot from galloping through the vineyards. The red grapes, unless specifically damaged by the hail, did not otherwise suffer. At harvest time, the producers felt happy to have escaped disaster.They did not expect anything remarkable from the vintage and indeed the start of the vinification process was not especially auspicious, with the grapes reluctant to hand over their colour and fruit. But by the time the new wine was ready to be decanted out of the vats into barrels, producers were sounding a lot more confident.Some had chosen to go with the style of the vintage and keep extraction to the minimum; others wished to compensate for the reluctance of the fruit to emerge initially, and had gone for a longer than usual vinification. Many fewer stems were used in 2010 than the previous year.Jasper Morris MW, BBR Buyer Jasper divides his time between England and Burgundy. His unique position led him to write the ultimate guide to the vineyards of the region,Inside Burgundy. Described as “the greatest reference work of our generation” by Bill Nanson (www.burgundyreport. com), and “an essential book for anyone remotely interested in the region and its wines” by Neal Martin (), this outstandingly detailed book, in 656 pages, covers one thousand specific vineyards, from Grands Crus to obscure plots.Region:Gevrey ChambertinGevrey-Chambertin is the largest wine-producing village in Burgundy’s Côte d'Or, with its vineyards spilling over into the next door commune of Brochon. Located in the far north of the Côtes de Nuits above Morey St Denis, classic Gevrey Chambertin is typically deeper in colour, firmer in body and more tannic in structure than most red Burgundy. The best can develop into the richest, most complete and long-lived Pinot Noir in the world.This is largely thanks to the iron-rich clay soils, though much depends on whether the vineyard is located on either the steeper slopes (Evocelles,Clos St Jacques) or the richer, flatter soils (Clos Prieur,Combottes).Whereas in the past there have been numerous underperformers in Gevrey-Chambertin, exploiting the reputation of this famous village and its iconic Grand Crus, today there are many fine sources to choose from, and overall quality is higher than ever.Gevrey-Chambertin’s greatest Grand Cru is named after the field of the monk Bertin (Champ de Bertin). In 1847 Gevrey appended the name of this illustrious vineyard,Chambertin, starting a trend for the other main villages to follow. Le Chambertin may not be quite as sumptuous as Musigny or Richebourg or as divinely elegant as La Tâche or Romanée St Vivant, but it is matched only by the legendary Romanée-Conti for completeness and luscious intensity.In all Gevrey boasts an impressive 9 Grands Crus, with the name of Chambertin retaining a regal omnipresence throughout its finest vineyard names. The other truly great Grand Cru is Chambertin Clos de Bèze which has the right to sell its wines simply as ‘Chambertin’ and is the only wine allowed to put the Chambertin name before, rather than after, its own.Situated slightly further up the hill, the wines are fractionally less powerful but are full of sensual charm and finesse.Quality-wise the next best are generally acknowledged to be Mazis- (or Mazy-) Chambertin and Latricières-Chambertin. The former is incredibly concentrated and very fine but its structure is a little less firm than Le Chambertin. Latricières is less about power, although it can be explosively fruity, and more about an entrancing silkiness.Situated slightly higher up the slope,Ruchottes-Chambertin is impressively rich, stylish and slightly angular. The tiny Griottes-Chambertin, which owes its name to the grill-pan shape of the vineyard rather than the wine’s Griottes cherry aroma, is lower down the slope and boasts a velvety texture and rich fruit reminiscent of Chambertin itself. It is generally better than the lighter although wonderfully fragrant Chapelle-Chambertin and Gevrey’s largest Grand Cru, the pure and seductive (if variable)Charmes-Chambertin.Gevrey also has some outstanding Premier Crus on the south-east-facing slopes above the town.Les Cazetiers and especially Clos St Jacques produce some exceptional wines. Indeed Armand Rousseau, who pioneered domaine bottling here in the 1930s and is still one of the region’s very best producers, often sells his Clos St Jacques for more than several of his Grand Crus.Drinking dates for these wines vary, but Grand Crus are generally best from at least 10 to 25 years, Premier Crus from 8 to 20 years and village wines from 5 to 12 years.•315 hectares of village Gevrey Chambertin.•84 hectares of Premier Cru vineyards(20 in all). Best vineyards include Clos St Jacques, Lavaux St Jacques, Combottes, Corbeaux, Cherbaudes, Cazetiers.•55 hectares of Grand Cru vineyards- Chambertin, Chambertin Clos de Bèze, Latricières-Chambertin, Ruchottes-Chambertin, Mazis-Chambertin, Charmes-Chambertin, Mazoyères-Chambertin, Chapelle-Chambertin, Griottes-Chambertin..•Recommended Producers:Bachelet,Dugat,Esmonin,Mortet,Rossignol Trapet,Rousseau,Serafin•Recommended Restaurants: Chez Guy (good wine list), Rôtisserie du Chambertin (and Bistro)Grape:Pinot NoirPinot Noir is probably the most frustrating, and at times infuriating, wine grape in the world. However when it is successful, it can produce some of the most sublime wines known to man. This thin-skinned grape which grows in small, tight bunches performs well on well-drained, deepish limestone based subsoils as are found on Burgundy's Côte D'Or. Pinot Noir is more susceptible than other varieties to over cropping - concentration and varietal character disappear rapidly if yields are excessive and yields as little as 25hl/ha are the norm for some climats of the Côte D`Or.Because of the thinness of the skins, Pinot Noir wines are lighter in colour, body and tannins. However the best wines have grip, complexity and an intensity of fruit seldom found in wine from other grapes. Young Pinot Noir can smell almost sweet, redolent with freshly crushed raspberries, cherries and redcurrants. When mature, the best wines develop a sensuous, silky mouth feel with the fruit flavours deepening and gamey "sous-bois" nuances emerging.The best examples are still found in Burgundy, although Pinot Noir`s key role in Champagne should not be forgotten. It is grown throughout the world with notable success in the Carneros and Russian River Valley districts of California, and the Martinborough and Central Otago regions of New Zealand.。

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the importance of a proper understanding of these more theoretical aspects of the subject. Some of the theory you learn could prove useful in other applications of mathematics. ∙ Lectures I recommend that you take some notes during the lectures, if only to capture the examples I give. You might also find it helpful to read the relevant sections of the textbook even before the lecture. The order of the course will be almost the same as the schedule on the textbook, so you should know what’s coming. ∙ Exercises In this course, as in other courses in Mathematics, it is very important that you finish all the exercises specified, and hand them in for grading by every Monday. There is a big difference between watching other people carry out calculations and being able to do them yourself, and it is vital that you get practice in the various techniques covered in the course. It is also important that you hand the work in, so that you can get feedback on whether your work is presented in an appropriate way. Exercises will be set every week. They will be taken directly from the course textbook. About one-third of the exercises on the textbook will be specified, but students are expected to attempt all the exercises behind each chapter. ∙ Teaching and Learning Methods Two lectures each week, one on Monday and one on Wednesday from 15:50-18:15. Total learning hours is about 72. The learning methods dependent on you. Any methods which has be proven to be successful to you is still applicable. ∙ Learning Materials There are many books on Advanced Algebra most of which have much the same title and contain much the same material. Our Textbook: Guohua Peng and Delang Li, Linear Algebra, Higher Education Press, 2006 The following books are recommended for references 1. Beida, Advanced Algebra (Chinese), Higher Education Press 2. B. Jacob, Linear Algebra, W.H. Freeman and Company, 1990 3. N. Jacobson, Basic Algebra, W.H. Freeman and Company, 1985 4. L.W. Johnson, R.D. Riess and J.T. Arnold, Introduction to Linear Algebra (5th Edition), Prentice-Hall Inc. and China Machine Press, 2002 5. D.C. Lay, Linear Algebra and Its Applications (3rd Edition), Pearson Addison Wesley Asia Limited and Publishing House of Electronics Industry, 2003 6. G. Strang, Linear Algebra and Its Applications, International Thomson Publishing, 1988 Some materials online ♥ Some English e-books are available at /book/mp103.pdf /linearalgebra/ 2
♥ You can enter some related areas on Linear Algebra by the following web-page: /Science/Mathematics/Linear Algebra/ ♥ Related history of Linear algebra may be available at /library/topics/linear ♥ Some online modules designed to help you learn and practice basic linear algebra procedures such as Gauss-Jordan reduction, calculating the determinant, or checking for linear independence may be available at / bogacki/cgi-bin/lat.cgi ♥ You may obtain a lot of Chinese materials on Linear Algebra by searching “高等代数,精品 课程” through Google. ∙ Grading Your grade will be based on your accomplishment of homework (30%) and a final exam (70%). ∙ Credits 5, each semester ∙ Communication Since the teachers will leave Jiang’an campus, the students will have to ask questions during class. Make use of my class hours and class break to ask more questions, make comments, and just converse. If you prefer to contact with me by internet, please send email to me. My email address is peng@ And my Skype contact address is peng1728 You are also encouraged to see me in my office: Room South-211, Management Building, Wangjiang Campus. My office hour is 8:30-10:30 on Tuesday. I’m looking forward to getting to know you.
Lecture 1
Monday September 13, 2010 Guohua Peng
email: peng@
Contents
1 About The Course 2 Integers 1 3

About The Course
∙ Course Title: Linear Algebra I ∙ General Information Advanced Algebra is a vital, widely-used area of mathematics. It is a core mathematics course required of all the various mathematics majors and it is for students working on a degree in mathematics. The course material can be regarded as an elaboration of theory on polynomials and linear algebra. However, the level of abstraction and the emphasis on proof technique make this a difficult course for many students. Successful students emerge from the experience not only with a better understanding of advanced algebra, but also with a higher level of mathematical maturity, better equipped to deal with abstract concepts. The material covered in Advanced Algebra includes general theory on polynomials, systems of linear equations, matrices, determinants, linear spaces, linear maps, ������-matrices, Euclidean spaces, quadratic forms, and basic theory on multilinear algebra. These topics will be discussed in two successive semesters. Generally a subsequent course Abstract Algebra will be offered in the fifth semester. ∙ Aims The aim of this course is to introduce basic theory on polynomials and the basic ideas of linear algebra which are used throughout mathematics. A variety of key techniques are introduced for solving problems in the area. ∙ Learning Outcomes On successful completion of the course the student will have had considerable experience in solving linear equations using Gaussian elimination. The student should also have developed the ability to handle matrices of arbitrary size and to appreciate their geometrical significance. The calculation and use of determinants of square matrices should also be mastered as should the elementary aspects of eigenvalues and eigenvectors. The concept of linear spaces and linear maps are also very important in Advanced Algebra. The student should master how to describe them in terms of matrices. The accomplish of the course will involve learning some new practical skills, such as how to apply basic theory to symmetric matrices, and gaining an appreciation of how mathematical knowledge is extended through the notion of proof. The students will also learn some of the principles underlying these techniques, such as why linear spaces are useful and along the way you’ll see examples showing 1
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