ASSAY
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专利名称：ASSAY
发明人：AFFORD, Simon,WILHELM, Annika 申请号：GB2016/050199
申请日：20160129
公开号：WO2016/120632A1
公开日：
20160804
专利内容由知识产权出版社提供
专利附图：
摘要：The invention provides a method of diagnosis or prognosis of a chronic liver disease or inflammatory bowel disease (IBD) in a subject comprising providing a sample from the subject and measuring the amount of TWEAK (tumour necrosis factor-like weak inducer of apoptosis) in the sample, wherein if the amount of TWEAK is below a
predetermined level, then there is an increased risk that the subject has a chronic liver disease or has a poor prognosis of the chronic liver disease, or if the amount is above a predetermined level then there is an increased risk that the subject has IBD. The invention also provides a method of determining the effect of treatment on a chronic liver disease comprising providing measuring the amount of TWEAK in a first sample from a subject, provided before the treatment and comparing it to an amount of TWEAK in a second sample from a subject provided after treatment, wherein an increase in TWEAK between the first and second samples indicates that the chronic liver disease is being treated. Assay kits for use in the invention are also provided.
申请人：THE UNIVERSITY OF BIRMINGHAM
地址：B15 2TT GB
国籍：GB
代理人：WITHERS & ROGERS LLP et al.
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