Betrixaban_330942-05-7_DataSheet_MedChemExpress
碧云天生物技术 Beyotime Biotechnology 生物素标记EMSA探针说明书
碧云天生物技术/Beyotime Biotechnology订货热线：400-168-3301或800-8283301订货e-mail：******************技术咨询：*****************网址：碧云天网站微信公众号生物素标记EMSA探针－β-Catenin/TCF (0.2μM)产品编号产品名称包装GS018B 生物素标记EMSA探针－β-Catenin/TCF (0.2µM) 200µl产品简介：生物素标记EMSA探针－β-Catenin/TCF是用于EMSA(也称gel shift)研究的生物素(Biotin)标记的β-Catenin/TCF consensus oligonucleotide。
这个生物素标记的双链寡核苷酸含有公认的β-Catenin/TCF结合位点，可以用作EMSA研究时的探针。
β-Catenin/TCF consensus oligo的序列如下：5'-CCC TTT GAT CTT ACC-3'3'-GGG AAA CTA GAA TGG-5'本生物素标记EMSA探针已经过纯化，可以直接用于EMSA结合反应。
本生物素标记EMSA探针可以和碧云天的化学发光法EMSA试剂盒(GS009)配套使用。
一个包装的生物素标记探针可以进行约200-400个样品的EMSA检测。
包装清单：产品编号产品名称包装GS018B 生物素标记EMSA探针－β-Catenin/TCF (0.2µM) 200µl—说明书1份保存条件：-20ºC保存，一年有效。
注意事项：避免加热到40ºC以上，温度过高会导致双链DNA探针解聚成单链。
而单链无法用于EMSA研究。
对于基于生物素标记的EMSA检测的详细操作可以参考碧云天的化学发光法EMSA试剂盒(GS009)的使用说明。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
AT28HC64B高性能电擦可编程只读存储器（EEPROM）说明书
Features Array•Fast Read Access Time – 70 ns•Automatic Page Write Operation–Internal Address and Data Latches for 64 Bytes•Fast Write Cycle Times–Page Write Cycle Time: 10 ms Maximum (Standard)2 ms Maximum (Option – Ref. AT28HC64BF Datasheet)–1 to 64-byte Page Write Operation•Low Power Dissipation–40 mA Active Current–100µA CMOS Standby Current•Hardware and Software Data Protection•DATA Polling and Toggle Bit for End of Write Detection•High Reliability CMOS Technology–Endurance: 100,000 Cycles–Data Retention: 10 Years•Single 5 V ±10% Supply•CMOS and TTL Compatible Inputs and Outputs•JEDEC Approved Byte-wide Pinout•Industrial Temperature Ranges•Green (Pb/Halide-free) Packaging Option Only1.DescriptionThe AT28HC64B is a high-performance electrically-erasable and programmable read-only memory (EEPROM). Its 64K of memory is organized as 8,192 words by 8 bits. Manufactured with Atmel’s advanced nonvolatile CMOS technology, the device offers access times to 55 ns with power dissipation of just 220 mW. When the device is deselected, the CMOS standby current is less than 100µA.The AT28HC64B is accessed like a Static RAM for the read or write cycle without the need for external components. The device contains a 64-byte page register to allow writing of up to 64 bytes simultaneously. During a write cycle, the addresses and 1 to 64 bytes of data are internally latched, freeing the address and data bus for other operations. Following the initiation of a write cycle, the device will automatically write the latched data using an internal control timer. The end of a write cycle can be detected by DATA polling of I/O7. Once the end of a write cycle has been detected, a new access for a read or write can begin.Atmel’s AT28HC64B has additional features to ensure high quality and manufactura-bility. The device utilizes internal error correction for extended endurance and improved data retention characteristics. An optional software data protection mecha-nism is available to guard against inadvertent writes. The device also includes anextra 64 bytes of EEPROM for device identification or tracking.20274L–PEEPR–2/3/09AT28HC64B2.Pin Configurations2.128-lead SOIC Top ViewPin Name Function A0 - A12Addresses CE Chip Enable OE Output Enable WE Write Enable I/O0 - I/O7Data Inputs/Outputs NC No Connect DCDon’t Connect2.232-lead PLCC Top ViewNote:PLCC package pins 1 and 17 are Don’t Connect.2.328-lead TSOP Top View30274L–PEEPR–2/3/09AT28HC64B3.Block Diagram4.Device Operation4.1ReadThe AT28HC64B is accessed like a Static RAM. When CE and OE are low and WE is high, the data stored at the memory location determined by the address pins is asserted on the out-puts. The outputs are put in the high-impedance state when either CE or OE is high. This dual line control gives designers flexibility in preventing bus contention in their systems.4.2Byte WriteA low pulse on the WE or CE input with CE or WE low (respectively) and OE high initiates a write cycle. The address is latched on the falling edge of CE or WE, whichever occurs last. The data is latched by the first rising edge of CE or WE. Once a byte write has been started, it will automatically time itself to completion. Once a programming operation has been initiated and for the duration of t WC , a read operation will effectively be a polling operation.4.3Page WriteThe page write operation of the AT28HC64B allows 1 to 64 bytes of data to be written into the device during a single internal programming period. A page write operation is initiated in the same manner as a byte write; after the first byte is written, it can then be followed by 1 to 63 additional bytes. Each successive byte must be loaded within 150 µs (t BLC ) of the previous byte. If the t BLC limit is exceeded, the AT28HC64B will cease accepting data and commence the internal programming operation. All bytes during a page write operation must reside on the same page as defined by the state of the A6 to A12 inputs. For each WE high-to-low transition during the page write operation, A6 to A12 must be the same.The A0 to A5 inputs specify which bytes within the page are to be written. The bytes may be loaded in any order and may be altered within the same load period. Only bytes which are specified for writing will be written; unnecessary cycling of other bytes within the page does not occur.4.4DATA PollingThe AT28HC64B features DATA Polling to indicate the end of a write cycle. During a byte or page write cycle, an attempted read of the last byte written will result in the complement of the written data to be presented on I/O7. Once the write cycle has been completed, true data is valid on all outputs, and the next write cycle may begin. DATA Polling may begin at any time during the write cycle.40274L–PEEPR–2/3/09AT28HC64B4.5Toggle BitIn addition to DATA Polling, the AT28HC64B provides another method for determining the end of a write cycle. During the write operation, successive attempts to read data from the device will result in I/O6 toggling between one and zero. Once the write has completed, I/O6 will stop toggling, and valid data will be read. Toggle bit reading may begin at any time during the write cycle.4.6Data ProtectionIf precautions are not taken, inadvertent writes may occur during transitions of the host system power supply. Atmel ® has incorporated both hardware and software features that will protect the memory against inadvertent writes.4.6.1Hardware ProtectionHardware features protect against inadvertent writes to the AT28HC64B in the following ways: (a) V CC sense – if V CC is below 3.8 V (typical), the write function is inhibited; (b) V CC power-on delay – once V CC has reached 3.8 V, the device will automatically time out 5 ms (typical) before allowing a write; (c) write inhibit – holding any one of OE low, CE high or WE high inhib-its write cycles; and (d) noise filter – pulses of less than 15 ns (typical) on the WE or CE inputs will not initiate a write cycle.4.6.2Software Data ProtectionA software-controlled data protection feature has been implemented on the AT28HC64B. When enabled, the software data protection (SDP), will prevent inadvertent writes. The SDP feature may be enabled or disabled by the user; the AT28HC64B is shipped from Atmel with SDP disabled.SDP is enabled by the user issuing a series of three write commands in which three specific bytes of data are written to three specific addresses (refer to the “Software Data Protection Algorithm” diagram on page 10). After writing the 3-byte command sequence and waiting t WC , the entire AT28HC64B will be protected against inadvertent writes. It should be noted that even after SDP is enabled, the user may still perform a byte or page write to the AT28HC64B. This is done by preceding the data to be written by the same 3-byte command sequence used to enable SDP.Once set, SDP remains active unless the disable command sequence is issued. Power transi-tions do not disable SDP, and SDP protects the AT28HC64B during power-up and power-down conditions. All command sequences must conform to the page write timing specifica-tions. The data in the enable and disable command sequences is not actually written into the device; their addresses may still be written with user data in either a byte or page write operation.After setting SDP, any attempt to write to the device without the 3-byte command sequence will start the internal write timers. No data will be written to the device, however. For the dura-tion of t WC , read operations will effectively be polling operations.4.7Device IdentificationAn extra 64 bytes of EEPROM memory are available to the user for device identification. By raising A9 to 12 V ±0.5 V and using address locations 1FC0H to 1FFFH, the additional bytes may be written to or read from in the same manner as the regular memory array.50274L–PEEPR–2/3/09AT28HC64BNotes:1.X can be VIL or VIH.2.See “AC Write Waveforms” on page 8.3.VH = 12.0 V ±0.5 V.Note:1.I SB1 and I SB2 for the 55 ns part is 40 mA maximum.5.DC and AC Operating RangeAT28HC64B-70AT28HC64B-90AT28HC64B-120Operating Temperature (Case)-40°C - 85°C -40°C - 85°C -40°C - 85°C V CC Power Supply5 V ±10%5 V ±10%5 V ±10%6.Operating ModesMode CE OE WE I/O Read V IL V IL V IH D OUT Write (2)V IL V IH V IL D IN Standby/Write Inhibit V IH X (1)X High ZWrite Inhibit X X V IH Write Inhibit X V IL X Output Disable X V IH XHigh ZChip Erase V ILV H (3)V IL High Z7.Absolute Maximum Ratings*Temperature Under Bias................................-55°C to +125°C *NOTICE:Stresses beyond those listed under “Absolute Maximum Ratings” may cause permanent dam-age to the device. This is a stress rating only and functional operation of the device at these or any other conditions beyond those indicated in the operational sections of this specification is not implied. Exposure to absolute maximum rating conditions for extended periods may affect device reliabilityStorage Temperature.....................................-65°C to +150°C All Input Voltages(including NC Pins)with Respect to Ground.................................-0.6 V to +6.25 V All Output Voltageswith Respect to Ground...........................-0.6 V to V CC + 0.6 V Voltage on OE and A9with Respect to Ground..................................-0.6 V to +13.5V8.DC CharacteristicsSymbol Parameter ConditionMinMax Units I LI Input Load Current V IN = 0 V to V CC + 1 V 10µA I LO Output Leakage Current V I/O = 0 V to V CC10µA I SB1V CC Standby Current CMOS CE = V CC - 0.3 V to V CC + 1 V 100(1)µA I SB2V CC Standby Current TTL CE = 2.0 V to V CC + 1 V 2(1)mA I CC V CC Active Current f = 5 MHz; I OUT = 0 mA40mA V IL Input Low Voltage 0.8V V IH Input High Voltage 2.0V V OL Output Low Voltage I OL = 2.1 mA 0.40V V OH Output High VoltageI OH = -400 µA2.4V60274L–PEEPR–2/3/09AT28HC64B10.AC Read Waveforms (1)(2)(3)(4)Notes:1.CE may be delayed up to t ACC - t CE after the address transition without impact on t ACC .2.OE may be delayed up to t CE - t OE after the falling edge of CE without impact on t CE or by t ACC - t OE after an address changewithout impact on t ACC .3.t DF is specified from OE or CE whichever occurs first (C L = 5 pF).4.This parameter is characterized and is not 100% tested.9.AC Read CharacteristicsSymbol ParameterAT28HC64B-70AT28HC64B-90AT28HC64B-120Units MinMax MinMax MinMax t ACC Address to Output Delay 7090120ns t CE (1)CE to Output Delay 7090120ns t OE (2)OE to Output Delay 035040050ns t DF (3)(4)OE to Output Float 035040050ns t OHOutput Hold00ns70274L–PEEPR–2/3/09AT28HC64B11.Input Test Waveforms and Measurement Level12.Output Test LoadNote:1.This parameter is characterized and is not 100% tested.R F 13.Pin Capacitancef = 1 MHz, T = 25°C (1)Symbol Typ Max Units Conditions C IN 46pF V IN = 0 V C OUT 812pFV OUT = 0 V815.AC Write Waveforms15.1WE Controlled15.2CE Controlled14.AC Write CharacteristicsSymbol ParameterMin MaxUnits t AS , t OES Address, OE Setup Time 0ns t AH Address Hold Time 50ns t CS Chip Select Setup Time 0ns t CH Chip Select Hold Time 0ns t WP Write Pulse Width (WE or CE)100ns t DS Data Setup Time 50ns t DH , t OEHData, OE Hold Timens90274L–PEEPR–2/3/09AT28HC64B17.Page Mode Write Waveforms (1)(2)Notes: 1.A6 through A12 must specify the same page address during each high to low transition of WE (or CE).2.OE must be high only when WE and CE are both low.18.Chip Erase Waveformst S = t H = 5 µs (min.)t W = 10 ms (min.)V H = 12.0 V ±0.5 V16.Page Mode CharacteristicsSymbol Parameter MinMax Units t WC Write Cycle Time10ms t WC Write Cycle Time (Use AT28HC64BF))2ms t AS Address Setup Time 0ns t AH Address Hold Time 50ns t DS Data Setup Time 50ns t DH Data Hold Time 0ns t WP Write Pulse Width 100ns t BLC Byte Load Cycle Time 150µs t WPHWrite Pulse Width High50ns100274L–PEEPR–2/3/09AT28HC64B19.Software Data Protection EnableAlgorithm (1)Notes:1.Data Format: I/O7 - I/O0 (Hex);Address Format: A12 - A0 (Hex).2.Write Protect state will be activated at end of writeeven if no other data is loaded.3.Write Protect state will be deactivated at end of writeperiod even if no other data is loaded.4.1 to 64 bytes of data are loaded.20.Software Data Protection DisableAlgorithm (1)Notes:1.Data Format: I/O7 - I/O0 (Hex);Address Format: A12 - A0 (Hex).2.Write Protect state will be activated at end of writeeven if no other data is loaded.3.Write Protect state will be deactivated at end of writeperiod even if no other data is loaded.4. 1 to 64 bytes of data are loaded.21.Software Protected Write Cycle Waveforms (1)(2)Notes:1.A6 through A12 must specify the same page address during each high to low transition of WE (or CE) after the softwarecode has been entered.2.OE must be high only when WE and CE are both low.11AT28HC64BNote:1.These parameters are characterized and not 100% tested. See “AC Read Characteristics” on page 6.23.Data Polling WaveformsNotes:1.These parameters are characterized and not 100% tested.2.See “AC Read Characteristics” on page 6.25.Toggle Bit Waveforms (1)(2)(3)Notes: 1.Toggling either OE or CE or both OE and CE will operate toggle bit.2.Beginning and ending state of I/O6 will vary.3.Any address location may be used, but the address should not vary.22.Data Polling Characteristics (1)Symbol Parameter Min TypMaxUnits t DH Data Hold Time 0ns t OEH OE Hold Time 0ns t OE OE to Output Delay (1)ns t WR Write Recovery Timens24.Toggle Bit Characteristics (1)Symbol Parameter Min TypMaxUnits t DH Data Hold Time 10ns t OEH OE Hold Time 10ns t OE OE to Output Delay (2)ns t OEHP OE High Pulse 150ns t WR Write Recovery Timens12AT28HC64B26.Normalized I CCGraphs13AT28HC64B27.Ordering Information27.1Green Package Option (Pb/Halide-free)t ACC (ns)I CC (mA)Ordering Code Package Operation RangeActive Standby 70400.1AT28HC64B-70TU 28T Industrial (-40°C to 85°C)AT28HC64B-70JU 32J AT28HC64B-70SU 28S 90400.1AT28HC64B-90JU 32J AT28HC64B-90SU 28S AT28HC64B-90TU 28T 120400.1AT28HC64B-12JU 32J AT28HC64B-12SU28SPackage Type32J 32-lead, Plastic J-leaded Chip Carrier (PLCC)28S 28-lead, 0.300" Wide, Plastic Gull Wing Small Outline (SOIC)28T28-lead, Plastic Thin Small Outline Package (TSOP)27.2Die ProductsContact Atmel Sales for die sales options.28.Packaging Information 28.132J – PLCC14AT28HC64BAT28HC64B 28.228S – SOIC1528.328T – TSOP16AT28HC64BHeadquarters InternationalAtmel Corporation 2325 Orchard Parkway San Jose, CA 95131 USATel: 1(408) 441-0311 Fax: 1(408) 487-2600Atmel AsiaUnit 1-5 & 16, 19/FBEA Tower, Millennium City 5418 Kwun Tong RoadKwun Tong, KowloonHong KongTel: (852) 2245-6100Fax: (852) 2722-1369Atmel EuropeLe Krebs8, Rue Jean-Pierre TimbaudBP 30978054 Saint-Quentin-en-Yvelines CedexFranceTel: (33) 1-30-60-70-00Fax: (33) 1-30-60-71-11Atmel Japan9F, Tonetsu Shinkawa Bldg.1-24-8 ShinkawaChuo-ku, Tokyo 104-0033JapanTel: (81) 3-3523-3551Fax: (81) 3-3523-7581Product ContactWeb SiteTechnical Support******************Sales Contact/contactsLiterature Requests/literatureDisclaimer: The information in this document is provided in connection with Atmel products. No license, express or implied, by estoppel or otherwise, to any intellectual property right is granted by this document or in connection with the sale of Atmel products. EXCEPT AS SET FORTH IN ATMEL’S TERMS AND CONDI-TIONS OF SALE LOCATED ON ATMEL’S WEB SITE, ATMEL ASSUMES NO LIABILITY WHATSOEVER AND DISCLAIMS ANY EXPRESS, IMPLIED OR STATUTORY WARRANTY RELATING TO ITS PRODUCTS INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTY OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE, OR NON-INFRINGEMENT. IN NO EVENT SHALL ATMEL BE LIABLE FOR ANY DIRECT, INDIRECT, CONSEQUENTIAL, PUNITIVE, SPECIAL OR INCIDEN-TAL DAMAGES (INCLUDING, WITHOUT LIMITATION, DAMAGES FOR LOSS OF PROFITS, BUSINESS INTERRUPTION, OR LOSS OF INFORMATION) ARISING OUT OF THE USE OR INABILITY TO USE THIS DOCUMENT, EVEN IF ATMEL HAS BEEN ADVISED OF THE POSSIBILITY OF SUCH DAMAGES. Atmel makes no representations or warranties with respect to the accuracy or completeness of the contents of this document and reserves the right to make changes to specifications and product descriptions at any time without notice. Atmel does not make any commitment to update the information contained herein. Unless specifically provided otherwise, Atmel products are not suitable for, and shall not be used in, automotive applications. Atmel’s products are not intended, authorized, or warranted for use as components in applications intended to support or sustain life.© 2009 Atmel Corporation. All rights reserved. Atmel®, logo and combinations thereof, and others are registered trademarks or trademarks of Atmel Corporation or its subsidiaries. Other terms and product names may be trademarks of others.。
派特克溶解氧传感器和发射器应用说明书
AVAILABLETRANSMITTERS7300w 2 Monitor Atlantic Monitor 840 TransmitterMOUNTING OPTIONS FlexT ech Probe HolderFlowcell Fixed Dip T ubeMEASUREMENT PRINCIPLESelf Polarising Self T emperature Compensating, Galvanic, membranecovered cellFEATURESLong life probe – 5 years+Very low maintenanceEasy to calibrateBENEFITSImproved Aeration Control Prevention of Discharge FailureEnergy SavingsPartech Galvanic Sensors and T ransmittersAPPLICATION DATASHEETBeing able to act on accurate measurements of Dissolved Oxygen in activated sludge plants will enable you to maintain levels of bacterial activity, avoid breaches in discharge consents and operate as cost effectively as possible. T oo little dissolved oxygen can lead to bacterial inactivity and ineffective treatment, whilst too much, wastes energy and can cause unnecessary wear and tear to the aeration system.Partech's sensors make accurate dissolved oxygen measurement easy. They are highly reliable and accurate as well as straightforward to use and easy to install. They also benefit from the self cleaning action of the Pioneer probe holder and the fouling tolerance of the probes themselves – all of which mean longer service intervals and a consistently more efficient plant.The Oxyguard probe utilises a unique combination of electrolyte, membrane and anode materials, together these factors give a real world working life in excess of five years. The Iron/Silver electrode combination ensures that no gas can build up in the cell and the electrolyte is not consumed, there is no warm up time and no zero adjustment required. The only maintenance is occasional removal of fouling and calibration.Routine calibration is required for any instrumentation, without it there is no validation of the measurement. The Oxyguard probe is easily repaired on site without specialist training, the membrane is quick and easy to replace.T ransmitter OptionsPRODUCT DATASHEET7300w2 MonitorPartech's latest generation, multisensor,multiparameter monitor provides an exceptionally flexible solutionto monitoring water, wastewater and surface water parameters such as Dissolved Oxygen. The monitorallows the user to combine multiple sensors for use on large sites and to add parameters such as pH,andSuspended Solids.840 TransmitterThe 840 T ransmitter is a loop powered device designed for simplicity of use, the system can be selected withranges from 0-5 to 0-40 mg/l, or 0-5%Sat to 0-400%Sat. The only user requirement is to carry out periodiccalibration.Atlantic MonitorIn common with all the systems mentioned in this datasheet the probe will only need renovation if it isdamaged. In most applications the probe life is in excess of 5 years. Even when it does require attentionthere is no need to dispose of the probe,simply replace the membrane and electrolyte.The newly introduced Atlantic has been designed for applications where the Dissolved Oxygen system isused to control a process or where the system is required to produce alarms at different levels. It has 4relays and a 4 - 20 mA output, a 4 – 20 mA compensation input can be added.The Atlantic incorporates 8alarm set points.Calibration of the probe is done automatically and checked and validated by the system,the operator hasonly to remove the probe from the effluent, wipe it clean and leave it in air to temperature equilibrate. Oncethe temperature is stable press the button and the system completes and validates the calibration.EasyCal Calibration DeviceDesigned to improve the simplicity and reliability of the calibration the EasyCalcalibrates the probe at the point of measurement. This removes temperature as avariable which can have a very dramatic effect on the oxygen saturation in the air.The Easy Cal fits over the end of the probe, the probe is returned to the sample andair is blown across the membrane by a pump mounted in the EasyCal this is leftrunning for 10 minutes to allow it to temperature equilibrate with the sample andthen the calibration is performed by either setting the system to 100 % or to themg/l setting as displayed on the EasyCal.EasyCal can be used on the 7300w2, 840, or the Atlantic.Product BackgroundPRODUCT DATASHEETPartech and Dissolved OxygenFor over 30 years Partech has been a manufacturer and supplier of Dissolved Oxygen measurement systems. During this time we have gained experience of a wide range of measurement techniques and have amassed a huge knowledge of the trials and tribulations of DO measurement in Wastewater treatment.Since 1997, Partech have been the UK distributor for Oxyguard International of Denmark.During this time we have generated a large installed base of Oxyguard sensors in the UK.We are proud to continue this association with the integration of the famed Oxyguard probe into our product range.Currently Available Measurement CellsThe use of sensors to measure Dissolved Oxygen was started over 50 years ago by Dr Clark initially in the medical industry and then in water analysis. The Clark cell and it's close cousin the Makereth cell are electrochemical (galvanic)cells where an electrical circuit consisting of an anode and cathode with an electrolyte sitting behind a gas permeable membrane. As the oxygen diffuses through the membrane a chemical reaction takes place that generates an electrical signal that is proportional to the amount of Oxygen present in the sample. Oxyguard have developed their probe so that this electrochemical reaction does not consume the electrolyte or anode,thus providing a measuring cell that has an operational life of 10 years or more. Recently a technology from the 1970's has been revived, optical DO measurement has been offered as an alternative for all issues relating to monitoring in wastewater environments. Basically, the meter determines oxygen by measuring light.High-energy blue light is directed onto the sensor surface,which is coated with a luminescent material. Electrons of the luminescent material are excited to a higher energy level before then falling back to their basic energy level, emitting red light as they do so. This light is detected by a photo diode. Partech are now able to offer this technology in the WaterWatch2 range.Strength of the Partech solutionThe combined skills of Partech and Oxyguard with our reputations for simple, common sense solutions to measurement challenges means we can offer reliable Dissolved Oxygen measurement. Use of the FlexT ech mounting system helps alleviate the problems of fouling, and ensures that the sensor is located correctly for representative measurement. The unique combination of electrolyte, anode and cathode material, and physical probe design gives real world life of in excess of five years with many lasting much,much longer.The membrane for the cell is only replaced if it is damaged, there is no internal drift, and the internal sensor design means that the electrolyte and anode are not consumed.The Oxyguard probe benefits from being left alone, the first line of the maintenance section of the manual is 'Leave it alone'.PRODUCT DATASHEET Publication No: 221334DS-Iss03The company reserves the right to alter the specification without Probe Specifications Measurement PrincipleOxygen: galvanic oxygen partial pressure cell, self polarising, selftemperature compensating. T emperature: Precision NTC Dimensions Diameter: 58 mm Length: 59 mmWeight Probe only 0.2 kgProbe with 7 metres of cable: 0.5 kg Connections: Atlantic and 7300w 2: 4 lead840: 3 leadCable length (Std, other available)Atlantic: 7 metres840 and 7300w 2: 10 metresDO Measurement Range 0 – 20 mg/l (ppm) 0 – 200% sat, (higher on request) T emperature Range from -5°CAccuracy Depends on calibration and conditions. T ypically better than +/-1% of value.Output Stability In air at constant temperature stable to within +/-1% over 1 year Accuracy T emperature +/- 0.3COperating Conditions 0 – 40 C, Pressure to 2 bar. (higher on request)Storage temperature-5 to +60 CFlexT ech Mounting BracketThe FlexT ech mounting system has been designed to keep the DO probe in the optimum position within the matrix and provide a simple light weight and robust system to keep the probe clean and free of rags and other debris which slide off the shaft producing a self cleaning action.Fats and greases which are normally on the top of the sample tend to build up above the probe as it is mounted approximately 300 mm below the surface. An additional benefit of keeping the probe below surface is that is provides a more representative reading of the oxygen level in the tank, the surface being effected by rain and the natural tendency of oxygen to rise in the liquid.Alternative Mounting OptionsWhere a dip probe is not appropriate, alternative mounting options are available, such as a full bore flow through cell.Anti-Fouling CapThe Oxyguard anti-fouling Cap inhibits growths on the membrane of the probe, especially in seawater applications.The cap is essentially the same as the normal cap, but is fitted with a cone made from aspecially developed alloy. The cone surrounds the membrane and is effective in inhibiting marineorganisms from attaching to and growing on the membraneTypical Installation with a FlexTech Probe Holder63 m m I D140 mm75 m m O DFlow Through T-PieceSpecification and Mounting Details。
Flange-Seal
Bulletin 4353/UK March 2003Flange-Seal ™tube fittingsUsing the Parflange ® systemFluidConnectors Europe Sales OfficesBulletin 4353/UK© 2003 Parker HannifinAktuell 0303For further information on other Parker Products, call the European Product Information Centre free of charge on 00800 2727 5374.Internet: C ut o u t t h e b r a z i n g! U SSEO -L o kS E ALE RFOParker Hannifin Ges.mbH Badener Straße 12A-2700 Wiener Neustadt Tel:+43 2622 23501Fax:+43 2622 66212Parker Hannifin S.A.-N.V.Parc Industriel Sud Zone II23, Rue du Bosquet B-1400 Nivelles Tel:+32 67 280900Fax:+32 67 280999Parker Hannifin s.r.o.Dopravaku 723CZ-184 00 Prague 8Tel:+420 2 83085221Fax:+420 2 83085360Parker Hannifin GmbH FluidConnectors Group Am Metallwerk 9D-33659 Bielefeld T el :+49 521 4048-0Fax:+49 521 4048-4280Parker Hannifin Danmark A/S Industrigrenen 11DK-2635 IshøjTel:+45 43560400Fax:+45 43733107Parker Hannifin España S.A P .I. Las Monjas -C/.Estaciones, 8E-28850 T orrejón de Ardoz (Madrid)Tel:+34 91 6757300Fax:+34 91 6757711Parker Hannifin B.V.Edisonstraat 1Postbus 340NL-7570 AH Oldenzaal Tel:+31 541 585000Fax:+31 541 585459Parker Hannifin Sp.z.o.o.ul. Parowcowa 8B PL-02-445 Warszawa Tel:+48 22 8634942Fax:+48 22 8634944Parker Hannifin Portugal Lda Travessa da Bataria,184 - r/c Drto / 1° Esq.PT -4450-625 Leça da PalmeiraTel:+351 22 9997360Fax:+351 22 9961527Parker Hannifin Corporation Representation Office Moscow Trehprudny Pereulok 9, bld. 1B,Office 106RU-123001 Moscow Tel:+7 095 2340054Fax:+7 095 2340528Parker Hannifin AB Fagerstagatan 51Box 8314S-16308 Spånga-Stockholm Tel:+46 8 59795000Fax:+46 8 59795110Parker Hannifin Corporation vul. Velyka Vasylkivska 9/2Office 59UA-01004 KievTel:+380 44 2207432Fax:+380 44 2206534Parker Hannifin SA 17, Rue des Bûchillons Z.I. du Mt Blanc - BP 524F-74112 Annemasse Cedex Tel:+33 450878080Fax:+33 450378685Parker Hannifin Oy Ylästöntie 16FIN-01510 Vantaa Tel:+358 9 476731Fax:+358 9 47673200Parker Hannifin plc Haydock Park Road GB-Derby DE24 8JA Tel:+44 1332 365631Fax:+44 1332 368038Parker Hannifin S.p.A.Via Privata Archimede 1I-20094 Corsico (MI)Tel:+39 02 451921Fax:+39 02 4479340Parker Sales Ireland Ltd Bracetown Business Park Clonee, County Meath IE-Republic of Ireland Tel:+353 1 8014010Fax:+353 1 8014132Parker Hannifin India Pvt. Ltd.PLOT EL - 26, MIDC TTC Industrial Area,Mahape,IN-400709 Navi Mumbai Tel:+91 22 55907081Fax:+91 22 55907080Parker Hannifin A/SBerghagan - P .O. Box 3008N-1402 SkiTel:+47 64911000Fax:+47 64911090Flange-Seal systemConventional brazed onend vs. Flange sealFlexible systemOrbital flangingFlange-Seal system Flange-Seal testingFlange-Seal systemTube max. wall O.D.thickness (mm)tube to hose 6 1.58210212 2.516320 3.5Tube max. wallO.D.thickness Example PN (mm)tube to tube for St 37 NBK* 618 1.510 1.512216220 2.5Flange-Seal system Flange-Seal assembly instructionsL1Flange-Seal system1040 1025Flange-Seal system Flange-Seal assembly instructionsØ D1Dimensional check of the flare。
T-BERD 2207用户指南说明书
198150-15217-01Rev. DT-BERD 2207USER’S GUIDEThis manual applies to all T-BERD 2207 software incorporating software level 3.x.JANUARY 2000Copyright ©1998 TTC®USA 1-800-638-2049 • +1-301-353-1550 • FAX +1-301-353-0234Canada 1-888-689-2165 • +1-905-507-4117 • FAX +1-905-507-4126SECTION 9 - SpecificationsGeneral SpecificationsSECTION 9 SPECIFICATIONS9.1GENERAL SPECIFICATIONS9.1.1Physical Characteristics:Height:7.5" (19 cm)Width:11.5" (29.2 cm)Depth: 2.25" (5.7 cm)Weight: 4.25 lb. (1.93 kg.)9.1.2Environmental Characteristics:Temperature:Operating:32°F to 122°F (0°C to +50°C)Non-Operating:-40°F to 167°F (-40°C to +75°C)Humidity:10% to 90% Relative Humidity, non-condensing9.1.3Electrical Characteristics:Battery Type:10.8 V Nickel-Metal Hydride (NiMH)Operating Time:Typically, up to three hours of continuous operation on a full chargeRecharging Period:Maximum of two hours from full dischargeAC Adaptor:120VAC to 18 VDC 1.2A9.2DS1 SPECIFICATIONS9.2.1Input Specifications9.2.1.1RX JackConnector Type:Bantam jackFrequency:1,544,000 Hz ±5000 HzUser’s Guide T-BERD 22079-1SECTION 9 - SpecificationsDS1 SpecificationsImpedanceBRIDGE:1000 ohms minimumTERM:100 ohms ±5%DSX-MON:100 ohms ±5%RangeBRIDGE:+6 to -35.0 dBdsxTERM:+6 to -35.0 dBdsxDSX-MON:+6 to -24.0 dBdsx of resistive los9.2.1.2Loop Codes Detection CriteriaIn-Band:At least 177 error-free bits of the selected repetitive pattern must be received(loop up or loop down).Out-of-Band:Datalink monitored every 125 ms for loop codes (loop up and loop down).9.2.1.3Pattern Synchronization Detection CriteriaFixed Patterns:30 consecutive error-free bitsPseudo-random:30 + n consecutive error-free bits for a pattern length of 2^n-19.2.2Output Specifications9.2.2.1TX JackConnector Type:Bantam jackLBO Level:Line build-out of 0, -7.5, -15.0, and -22.5 dB of cable loss at 772 HzLBO Tolerance:±2 dB at 772 kHzTiming:±7 ppm internal or recoveredLine Codes:AMI or B8ZSError Insert Type:Logic, BP V, or FramePulse Shape:With output terminated in 100 ohms resistive load and 0 dB line build-outselected, the T-BERD 2207 meets ITU-T Recommendation G.703; AT&TPublications CB113, CB119, CB132, CB143, and PUB62508; and AT&TPUB62411 pulse shape specifications.9-2T-BERD 2207User’s GuideSECTION 9 - SpecificationsDS1 Specifications 9.2.2.2Transmitted Loop CodesIn-BandCSU:Loop-up: 10000; Loop-down: 100Facility 1:Loop-up: 1100; Loop-down: 1110Facility 2:Loop-up: 11000; Loop-down: 11100Facility 3:Loop-up: 100000; Loop-down: 100Out-of-BandLine:Loop up: 1111 1111 0111 0000Loop down: 1111 1111 0001 1100Payload:Loop up: 1111 1111 0010 1000Loop down: 1111 1111 0100 1100Network:Loop up: 1111 1111 0100 1000Loop down: 1111 1111 0010 01009.2.3Measurement SpecificationsFrequencyRange:1,544,000 ±5000 HzAccuracy:± 7 ppmResolution: 1 HzReceived LevelRange:+6 dBdsx to -40 dBdsxAccuracy:±1.0 dB between +6 and -10 dBdsx±2.0 dB between -10 and -20 dBdsx±3.0 dB between -20 and -40 dBdsxResolution:0.1 dBVp-p Range:60 mV to 12.0 VVp-p Resolution:0.05 VSimplex CurrentRange:10 mA to 180 mAccuracy:±5%Resolution: 1 mASimplex path:13.2 ohms (nominal)User’s Guide T-BERD 22079-3SECTION 9 - SpecificationsDS1 Specifications9.2.4Alarm CriteriaSignal Loss:175 ±75 consecutive zerosFrame LossD4: 2 out of 5 Ft bits in errorESF: 2 out of 5 frame bits in errorSLC-96: 2 out of 5 Ft bits in errorPattern Loss:100 errors detected in 1000 or fewer bitsOnes DensityQRSS:Alarm is suppressed.Other Patterns:Received data contains less than n ones in 8(n+1) bits, where n=1 to 23.Excess ZeroAMI:16 or more consecutive zerosB8ZS:8 or more consecutive zerosYellow AlarmD4:Bit 2 is a 0 for 255 consecutive channels.ESF:256 bits ±16 bits of a repetitive (1111 1111 0000 0000) pattern received inthe 4 kb/s datalink.SLC-96:Bit 2 is a 0 for 255 consecutive channels.AIS:Unframed T1 signal has 2048 consecutive ones.Low Battery:Battery has less than 25% energy remaining.9-4T-BERD 2207User’s GuideSECTION 9 - Specifications DS3 Option SpecificationsUser’s Guide T-BERD 22079-59.3DS3 OPTION SPECIFICATIONS9.3.1DS3 Specifications9.3.1.1Framing Formats9.3.1.2Patterns9.3.1.3Line Coding•B3ZS9.3.1.4Connectors•WECO 560A jack9.3.1.5Receiver (Single)Frequency:44,736 Mb/s ±300ppmLevel:HIGH: Accepts Nominal 1.2 Vp, 0 ft. of cable from High sourceDSX: Accepts Nominal 0.6 Vp, 450 ft. of c able from High source or monitor LOW: Accepts Nominal 0.3 Vp, 900 ft. of cable from High source9.3.1.6Transmitter (Single)Frequency:44,736 Mb/s ±20ppmPulse:HIGH: Nominal 1.2 Vp (Signal meets ANSI specification T1.102-1993 and ITU-TG.703 when subjected to 450 feet of cable loss.)•Auto• Muxed M13•Unframed • C-bit•M13• Muxed C-bit•1111• 215-1•1100 (Idle)• 220-1•1010 (AIS)• 223-1•1010• User (3 to 24 bit programmable)SECTION 9 - SpecificationsDS3 Option SpecificationsDSX: Nominal 0.91 Vp (Signal meets ANSI specification T1.102-1993 andITU-TG.703.)LOW: Nominal 0.31 VpTiming:Internal ClockRecovered Clock9.3.2DS3 Measurements9.3.2.1Summary•Bit Errors•Frame Errors•Bipolar Violations•Receive Frequenc•Parity Errors•FEAC Messages•C-bit Errors•DS2 Frame Errors•FEBE•Pattern Slip9.3.2.2Logic•Bit Errors•Pattern Slips•Bit Error Rate•Pattern Loss Seconds•Bit Errored Seconds•Error Free Seconds•Pattern Losses•% Error Free Seconds9.3.2.3Bipolar Violations•BPV•BPV Rate•BPV Errored Seconds9-6T-BERD 2207User’s GuideSECTION 9 - SpecificationsDS3 Option Specifications 9.3.2.4Frame Errors•Frame Error Rate•FEBE Rate•Frame Error Seconds•DS2 Frame Errors•Out of Frame Seconds•DS2 Frame Error Rate•C-bit Errors•Received X-bit•C-bit Error Rate•Transmit X-bit•FEBE•Frame Loss Count9.3.2.5Parity•Parity Errors•Parity Error Rate•Parity Error Seconds9.3.2.6Signal•Signal Loss•Signal Loss Seconds•Receive Frequency•Receive Signal Level•Transmit FrequencyUser’s Guide T-BERD 22079-7。
Extract-N-Amp Tissue PCR Kit 产品说明书
Product InformationExtract-N-Amp™ Tissue PCR KitXNAT2, XNAT2RProduct DescriptionThe Extract-N-Amp™ Tissue PCR Kit for direct PCR contains the reagents needed to rapidly extract and amplify genomic DNA from mouse tails and other animal tissues, buccal swabs, hair shafts, and saliva. Briefly, the DNA is released from the starting material by incubating the sample with a mixture of the Extraction Solution and the Tissue Preparation Solution at room temperature for 10 minutes. There is no need for mechanical disruption, organic extraction, column purification, or precipitation of the DNA.After adding Neutralization Solution B, the extract is ready for PCR. An aliquot of the neutralized extract is then combined with the Extract-N-Amp™ PCR Reaction Mix and user-provided PCR primers to amplify target DNA. The Extract-N-Amp™ PCR Reaction Mix is a 2X ready mix containing buffer, salts, dNTPs, and Taq polymerase. It is optimized specifically for use with the extraction reagents. It also contains the JumpStart Taq antibody for hot start PCR to enhance specificity but does not contain the inert red dye found in the REDExtract-N-Amp™ PCR Reaction Mix.Reagents Provided Cat. No. XNAT2 100 Preps,100 PCRsXNAT2R 1000 Preps, 1000 PCRsExtraction SolutionE7526 24 mL 240 mL Tissue Preparation Solution T3073 3 mL 30 mL Neutralization Solution BN391024 mL240 mLExtract-N-Amp™ PCR Reaction Mix This is a 2X PCR reaction mix containing buffer, salts, dNTPs, Taq polymerase, and JumpStart™ Taq antibody.E30041.2 mL12 mLReagents and Equipment Required(Not Provided)•Microcentrifuge tubes (1.5 or 2 mL) or multi-well plate for extractions (200 μL minimal well volume) • Small dissecting scissors• Forceps (small to medium in size)• Buccal swab - Sterile foam tipped applicator (Cat. No. WHAWB100032)•Sample collection card - Bloodstain card (Cat. No. WHAWB100014)• Tubes or plate for PCR• Heat block or thermal cycler at 95 °C • PCR Primers (Cat. No. OLIGO) • Thermal cycler•Water, PCR Reagent (Cat. No. W1754)Precautions and DisclaimerThis product is for R&D use only. Not for drug, household, or other uses. Please consult the Safety Data Sheet for information regarding hazards and safe handling practices.StorageThe Extract-N-Amp™ Tissue PCR Kit can be stored at 2 to 8 °C for up to 3 weeks. For long-term storage, greater than 3 weeks, -20 °C is recommended. Do not store in a "frost-free" freezer.ProcedureAll steps are carried out at room temperature unless otherwise noted.DNA Extraction from Mouse Tails, Animal Tissues, Hair, or Saliva1.Pipette 100 μL of Extraction Solution into amicrocentrifuge tube or well of a multi-well plate.Add 25 μL of Tissue Preparation Solution to thetube or well and pipette up and down to mix.Note: If several extractions will be performed,sufficient volumes of Extraction and TissuePreparation Solutions may be pre-mixed in a ratio of 4:1 up to 2 hours before use.2.For fresh or frozen mouse tails: Rinse thescissors and forceps in 70% ethanol prior to useand between different samples. Place a 0.5–1 cm piece of mouse tail tip (cut end down) into thesolution. Mix thoroughly by vortexing or pipetting.Ensure the mouse tail is in solution.Note: For fresh mouse tails, perform extractions within 30 minutes of snipping the tail.For animal tissues: Rinse the scissors or scalpel and forceps in 70% ethanol prior to use andbetween different samples. Place a 2–10 mgpiece of tissue into the solution. Mix thoroughlyby vortexing or pipetting. Ensure the tissue is inthe solution.For hair shafts: Rinse the scissors and forceps in 70% ethanol prior to use and between differentsamples. Trim excess off of the hair shaft leaving the root and place sample (root end down) intosolution. Only one hair shaft, with root, isrequired per extraction.For Saliva: Pipette 10 μL of saliva into thesolution. Mix thoroughly by vortexing or pipetting.For saliva dried on card: Pipette 50 μL of saliva onto collection card and allow the card to dry.Rinse the punch in 70% ethanol prior to use andbetween different samples. Punch a disk(preferably 1/8 inch or 3 mm) out of the cardfrom the area with the dried saliva sample. Place disk into the solution. Tap tube or plate on hardsurface to ensure disk is in solution forincubation period.3.Incubate sample at room temperature for10 minutes.4.Incubate sample at 95 °C for 3 minutes.Note: Tissues will not be completely digested atthe end of the incubations. This is normal and will not affect performance.5.Add 100 μL of Neutralization Solution B to sampleand mix by vortexing.6.Store the neutralized tissue extract at 4 °C oruse immediately in PCR amplification.Note: For long term storage, remove theundigested tissue or transfer the extracts tonew tubes or wells. Extracts may now be storedat 4 °C for at least 6 months without notable loss in most cases.DNA Extraction for Buccal Swabs1.Collect buccal cells on swab and allow theswab to dry. Drying time is approximately10 to 15 minutes.Note: Due to the low volume of solution used for DNA extraction, a foam tipped swab should beused. Swabs with fibrous tips, such as cotton orDacron®, should be avoided because the solution cannot be recovered efficiently.2.Pipette 200 μL of Extraction Solution into amicrocentrifuge tube. Add 25 μL of TissuePreparation Solution to the tube and pipette upand down to mix.Note: If several extractions will be performed,sufficient volumes of Extraction and TissuePreparation Solutions may be pre-mixed ina ratio of 8:1 up to 2 hours before use.3.Place dried buccal swab into solution and incubateat room temperature for 1 minute.4.Twirl swab in solution 10 times and then removeexcess solution from the swab into the tube bytwirling swab firmly against the side of the tube.Discard the swab. Close the tube andvortex briefly.5.Incubate sample at room temperature for10 minutes.6.Incubate sample at 95 °C for 3 minutes.7.Add 200 μL of Neutralization Solution B to sampleand mix by vortexing.8.Store the neutralized extract at 4 °C or useimmediately in PCR. Continue to PCRamplification.Note: Extracts may be stored at 4 °C for at least6 months without notable loss in most cases. PCR AmplificationThe Extract-N-Amp™ PCR Reaction Mix contains JumpStart™ Taq antibody for specific hot start amplification. Therefore, PCR mixtures can be assembled at room temperature without premature Taq DNA polymerase activity.Typical final primer concentrations are approximately 0.4 μM each. The optimal primer concentration and cycling parameters will depend on the system being used.1.Add the following reagents to a thin-walled PCRmicrocentrifuge tube or plate:Reagent VolumeWater, PCR grade VariableExtract-N-Amp™ PCRreaction mix 10 μLForward primer VariableReverse primer VariableTissue extract 4 μL*Total volume 20 μL*The Extract-N-Amp™ PCR Reaction Mix isformulated to compensate for components in the Extraction, Tissue Preparation, and Neutralization Solutions. If less than 4 µL of tissue extract isadded to the PCR reaction volume, use a 50:50mixture of Extraction and Neutralization BSolutions to bring the volume of tissue extract upto 4 μL.2.Mix gently.3.For thermal cyclers without a heated lid, add20 μL of mineral oil on top of the mixture in eachtube to prevent evaporation.4.Perform thermal cycling. The amplificationparameters should be optimized for individualprimers, template, and thermal cycler.Common cycling parameters:Step Temperature Time Cycles InitialDenaturation 94 °C 3 minutes 1 Denaturation 94 °C 30 seconds Annealing 45 to 68 °C 30 seconds 30-35 Extension 72 °C 1-2 minutes(1 min/kb)FinalExtension 72 °C 10 minutes 1 Hold 4 °C Indefinitely5.The amplified DNA can be loaded onto an agarosegel after the PCR is completed with the addition ofa separate loading buffer/tracking dye such as GelLoading Solution, Cat. No. G2526.Note: PCR products can be purified, if desired, fordownstream applications such as sequencing withthe GenElute PCR Clean-Up Kit, Cat. No.NA1020.Troubleshooting GuideProblem Cause SolutionLittle or no PCR product is detected. PCR reaction may beinhibited due tocontaminants in thetissue extract.Dilute the tissue extract with a 50:50 mix of Extractionand Neutralization Solutions. To test for inhibition, includea DNA control and/or spike a known amount of template(100-500 copies) into the PCR along with the tissue extract. Extraction isinsufficient.Incubate samples at 55 °C for 10 minutes instead ofroom temperature.A PCR component maybe missing or degraded.Run a positive control to ensure that componentsare functioning. A checklist is also recommendedwhen assembling reactions.There may be too fewcycles performed. Increase the number of cycles (5-10 additional cycles at a time). The annealingtemperature maybe too high.Decrease the annealing temperature in 2-4 °C increments.The primers may notbe designed optimally.Confirm the accuracy of the sequence information. If theprimers are less than 22 nucleotides long, try to lengthen theprimer to 25-30 nucleotides. If the primer has a GC contentof less than 45%, try to redesign the primer with a GCcontent of 45-60%.The extension timemay be too short.Increase the extension time in 1-minute increments, especiallyfor long templates.Target templateis difficult.In most cases, inherently difficult targets are due to unusuallyhigh GC content and/or secondary structure. Betaine, Cat. No.B0300, has been reported to help amplification of high GCcontent templates at a concentration of 1.0-1.7 M.Multiple products JumpStart™ Taqantibody is notworking correctly.Do not use DMSO or formamide with Extract-N-Amp™ PCRReaction Mix. It can interfere with the enzyme-antibodycomplex. Other cosolvents, solutes (e.g., salts), and extremesin pH or other reaction conditions may reduce the affinity ofthe JumpStart™ Taq antibody for Taq polymerase and therebycompromise its effectiveness.TouchdownPCR maybe needed.“Touchdown” PCR significantly improves the specificity of manyPCR reactions in various applications. Touchdown PCR involvesusing an annealing/extension temperature that is higher thanthe TM of the primers during the initial PCR cycles. Theannealing/extension temperature is then reduced to the primerTM for the remaining PCR cycles. The change can be performedin a single step or in increments over several cycles.Negative control shows a PCR product or “false positive” result. Reagents arecontaminated.Include a reagent blank without DNA template be included asa control in every PCR run to determine if the reagents used inextraction or PCR are contaminated with a template froma previous reaction.Tissue is not digested after incubations. Tissue is not expectedto be completelydigested.The REDExtract-N-Amp™ Tissue PCR Kit does not require thetissue to be completely digested. Sufficient DNA is released forPCR without completely digesting the tissue.Buccal swab absorbed all the solution. The recommended typeof swab was not used.Due to the low volume of solution used for DNA extraction, afoam tipped swab should be used. Swabs with fibrous tips, suchas cotton or Dacron®, should be avoided because the solutioncannot be recovered efficiently.References1.Dieffenbach, C.W., and Dveksler, G.S. (Eds.), PCRPrimer: A Laboratory Manual, 2nd ed., Cold Spring Harbor Laboratory Press, New York (1995).2.Don, R.H. et al., ‘Touchdown' PCR to circumventspurious priming during gene amplification.Nucleic Acids Res., 19, 4008 (1991).3.Erlich, H.A. (Ed.), PCR Technology: Principles andApplications for DNA Amplification, StocktonPress, New York (1989).4.Griffin, H.G., and Griffin, A.M. (Eds.), PCRTechnology: Current Innovations, CRC Press,Boca Raton, FL (1994).5.Innis, M.A., et al., (Eds.), PCR Strategies,Academic Press, New York (1995).6.Innis, M., et al., (Eds.), PCR Protocols: A Guide toMethods and Applications, Academic Press, SanDiego, California (1990).7.McPherson, M.J. et al., (Eds.), PCR 2: A PracticalApproach, IRL Press, New York (1995).8.Newton, C.R. (Ed.), PCR: Essential Data, JohnWiley & Sons, New York (1995).9.Roux, K.H. Optimization and troubleshooting inPCR. PCR Methods Appl., 4, 5185-5194 (1995).10.Saiki, R., PCR Technology: Principles andApplications for DNA Amplification, Stockton, New York (1989). Product OrderingOrder products online at Related Products Cat. No.Ethanol E7148; E7023; 459836 Forceps,micro-dissecting F4267PCR Marker P9577PCR microtubes Z374873; Z374962;Z374881PCR multi-well plates Z374903Precast Agarose Gels P6097Sealing mats & tapes Z374938; A2350TBE Buffer T4415, T6400, T9525The life science business of Merck operatesas MilliporeSigma in the U.S. and Canada.Merck, Extract-N-Amp, REDExtract-N-Amp, JumpStart, GenElute and Sigma-Aldrich are trademarks of Merck KGaA, Darmstadt, Germany or its affiliates. All other trademarks are theproperty of their respective owners. Detailed information on trademarks is available via publicly accessible resources.NoticeWe provide information and advice to our customers on application technologies and regulatory matters to the best of our knowledge and ability, but without obligation or liability. Existing laws and regulations are to be observed in all cases by our customers. This also applies in respect to any rights of third parties. Our information and advice do not relieve our customers of their own responsibility for checking the suitability of our products for the envisaged purpose. The information in this document is subject to change without notice and should not be construed as a commitment by the manufacturing or selling entity, or an affiliate. We assume no responsibility for any errors that may appear in this document. Technical AssistanceVisit the tech service page at/techservice.Terms and Conditions of SaleWarranty, use restrictions, and other conditions of sale may be found at /terms. Contact InformationFor the location of the office nearest you, go to /offices.。
P+F 安全珊Hart管理
eexcellence in dependable automationFMEDA including SFF determinationand PFD calculationProject:HART multiplexer KFD2-HMM-16 together with KFD0-HMS-16 and 2700 HART Signal MultiplexerCustomer:Pepperl+Fuchs GmbHMannheimGermanyContract No.: P+F 02/4-11Report No.: P+F 02/4-11 R006Version V1, Revision R1.2, July 2002Stephan AschenbrennerCONFIDENTIAL INFORMATIONManagement summaryThis report summarizes the results of the analysis carried out on the HART multiplexerKFD2-HMM-16 together with KFD0-HMS-16 and the 2700 HART Signal Multiplexer.The assessment does not contain an evaluation of the correct functioning of the HARTmultiplexer but a statement about the interference freeness on the safety related 4..20mAloop when used for HART communication with regard to the suitability in part for Safety Instrumented System (SIS) usage in a particular Safety Integrity Level (SIL).The failure rates are based on the Siemens standard SN 29500.According to table 2 of IEC 61508-1 the average PFD for systems operating in low demandmode has to be ≥10-4 to < 10-3 for SIL 3 safety functions and ≥10-3 to < 10-2 for SIL 2 safetyfunctions. However, as the modules under consideration are only one part of an entire safetyfunction they should not claim more than 10% of this range, i.e. they should be better than orequal to 10-4 for SIL 3 and better than or equal to 10-3 for SIL 2.The modules under evaluation can be considered to be Type B components. However, the components that can contribute to a disturbance of the safety system are considered to be TypeA components.For Type A components the SFF has to fulfill the requirements as stated in table 2 ofIEC 61508-2 which are the following:Hardware fault tolerance (HFT)0 1 2 SIL 2 60% ≤ SFF < 90% SFF < 60%SIL 3 90% ≤ SFF < 99% 60% ≤ SFF < 90% SFF < 60%The following tables show under which conditions the critical components of the two modulesthat can contribute to a disturbance of the safety system fulfill this requirement (considering onlyone communication line being part of the safety function).Table 1: KFD2-HMM-16 together with KFD0-HMS-16 without additional module interfaceT[Proof] = 1 year T[Proof] = 5 years T[Proof] = 10 yearsPFD AVG = 1.23E-06PFD AVG = 6.13E-06PFD AVG = 1.23E-05than 10% of this range, i.e. to be better than or equal to 10-3. The PFD values even fulfill the requirements of higher SILs but the system does only fulfill the architectural constraints requirements (HFT/SFF) for SIL 2 which are set by table 2 of IEC 61508-2 for type A components having a hardware fault tolerance of 0.If the HART multiplexer KFD2-HMM-16 and KFD0-HMS-16 are used together with the module interface as described in section 4.1 then two de-coupling capacitors have to fail to bring the (sub)system into a dangerous state. This corresponds to a hardware fault tolerance of 1.Table 2: KFD2-HMM-16 together with KFD0-HMS-16 with additional module interface T[Proof] = 1 year T[Proof] = 5 years T[Proof] = 10 yearsPFD AVG = 6.13E-08PFD AVG = 3.07E-07PFD AVG = 6.13E-07than 10% of this range, i.e. to be better than or equal to 10-4. The PFD values even fulfill the requirements of a higher SIL but the system does only fulfill the architectural constraints requirements (HFT/SFF) for SIL 3 which are set by table 2 of IEC 61508-2 for type A components having a hardware fault tolerance of 1.Table 3: 2700 HART Signal MultiplexerT[Proof] = 1 year T[Proof] = 5 years T[Proof] = 10 yearsPFD AVG = 2.50E-07PFD AVG = 1.25E-06PFD AVG = 2.50E-06than 10% of this range, i.e. to be better than or equal to 10-4. The PFD values even fulfill the requirements of higher SILs but the system does only fulfill the architectural constraints requirements (HFT/SFF) for SIL 3 which are set by table 2 of IEC 61508-2 for type A components having a hardware fault tolerance of 1.The calculations are based on the assumption that the HART multiplexer are mounted in an environment that is IP 54 compliant (e.g. housing, control cabinet or control room).Table of ContentsManagement summary (2)1Purpose and Scope (5)2Project management (5)2.1Roles of the parties involved (5)2.2Standards / Literature used (5)2.3Reference documents (6)2.3.1Documentation provided by the customer (6)2.3.2Documentation generated by (6)3Description of the HART communication (7)4Description of the analyzed modules (8)4.1KFD2-HMM-16 and KFD0-HMS-16 (8)4.22700 HART Signal Multiplexer (11)5Failure Modes, Effects, and Diagnostics Analysis (12)5.1Description of the failure categories (12)5.2Methodology – FMEDA, Failure rates (12)5.2.1FMEDA (12)5.2.2Failure rates (12)5.2.3Assumption (13)6Results of the assessment (13)6.1KFD2-HMM-16 and KFD0-HMS-16 (15)6.22700 HART Signal Multiplexer (17)7Terms and Definitions (19)8Status of the document (20)8.1Liability (20)8.2Releases (20)8.3Release Signatures (20)1 Purpose and ScopeThis report shall describe the results of the FMEDAs carried out on the HART multiplexer KFD2-HMM-16 together with KFD0-HMS-16 and the 2700 HART Signal Multiplexer.It shall be shown that the HART multiplexer do not electrically interfere with the connected safety related system when using the 4..20mA loop for the HART communication.It shall be assessed whether these modules meet the Probability of Failure on Demand (PFD) requirements for SIL 2 / SIL 3 sub-systems according to IEC 61508 with regard to the interference freeness on the safety related 4..20mA loop.The assessment does neither consider any calculations necessary for proving intrinsic safety nor an evaluation of the correct functioning of the HART multiplexer.Pepperl+Fuchs GmbH contracted in May 2002 with the FMEDA and PFD calculation of the above mentioned modules.2 Project management2.1 Roles of the parties involvedPepperl+Fuchs Manufacturer of the HART multiplexer. Did the FMEDAs together with the determination of the Safe Failure Fraction (SFF) and calculated the Probability of Failure on Demand (PFD)using Markov models.2.2 Standards / Literature usedThe services delivered by were performed based on the following standards / literature.[N1] IEC 61508-2:1999 Functional Safety of Electrical/Electronic/ProgrammableElectronic Safety-Related Systems[N2] ISBN: 0471133019 Electronic Components: Selection and Application Guidelinesby Victor MeeldijkJohn Wiley & Sons[N3] FMD-91, RAC 1991 Failure Mode / Mechanism Distributions[N4] SN 29500 Failure rates of components2.3 Reference documents2.3.1 Documentation provided by the customer[D1] DL0799, DL0800 of 21.04.01 Circuit diagram for KFD2-HMM-16 and KFD0-HMS-16 [D2] 107905 Bill of material for KFD2-HMM-16[D3] ES-984240/1-A1 of 18.11.99 Circuit diagram for 2700 HART Signal Multiplexer(Mother Board Multiplexer / Interface Circuit)[D4] CL-984240/1-A4 of 24.03.99 Bill of material for 2700 HART Signal Multiplexer (MotherBoard)[D5] ES-984240/2-A1 of 18.11.99 Circuit diagram for 2700 HART Signal Multiplexer(µProcessor Board)[D6] CL-984240/2-A3 of 16.03.99 Bill of material for 2700 HART Signal Multiplexer(µProcessor Board)[D7] Datasheet metallized polyester capacitor WIMA MKS 2 2.3.2 Documentation generated by [R1] FMEDA KFD2-HMM-16 V1 R1.0 – Analysis of 24.06.02[R2] FMEDA KFD2-HMM-16 V1 R1.0 – Results of 24.06.02[R3] FMEDA MUX 2700 V1 R1.0 – Analysis of 24.06.02[R4] FMEDA MUX 2700 V1 R1.0 – Results of 24.06.023 Description of the HART communicationThe HART1 protocol is supported by many conventional 4..20 mA field devices, which thus enable digital communication for configuration and servicing purposes. Many device parameters and also the measured values themselves can thus be digitally transferred to and from the device. This digital communication runs in parallel with the 4..20 mA signal on the same cable. This is possible through a current modulation, which is superimposed on the user signal.Figure 1: Modulated HART signalHART is a master-slave protocol: A field device does only respond when requested (except in "Burst mode").The message duration is several hundred milliseconds, so that between two and three messages can be transferred per second.On HART, there are three groups of commands:• The "Universal" commands; these must be supported by all field devices;• The "Common practice" commands; these are pre-defined commands, suitable for many field devices, which, if they are supported by the device, must be implemented in the pre-defined form;• Device-specific commands; these are commands, which are particularly suitable for this field device.1 HART = Highway Addressable Remote Transducer4 Description of the analyzed modulesIn safety-related applications the HART communication is used to provide additional (non safety-related) information about statuses and reading, allow for better preventive maintenance and thus improve the integrity of the field instrumentation.For this purpose the HART multiplexer have to be directly connected to the field wiring of the respective safety-related system (see Figure 2).Figure 2: Connection of the HART multiplexer with the safety-related system4.1 KFD2-HMM-16 and KFD0-HMS-16The HART multiplexer KFD2-HMM-16 can operate up to 256 analog transmitters. The built-in slave unit operates the first 16 loops, and a maximum of further 15 KFD0-HMS-16 slaves can be connected.The power supply (24 VDC nominal voltage) is provided via the power rail or terminals 17 and 18. The optional slave units or the RPI control module are connected with the master via a 14-core flat cable. Its connector is placed on the same housing side as the terminals for the RS 485 interface and the voltage supply.The analog signals for each unit are connected separately via a 26-core cable. 16 leads are provided for the HART signals of the analog instrument circuits, the other 10 are connected to ground.The minimum load resistance of the analog instrument circuits is 230 Ω (min. load resistance in accordance with the HART specification), the max. load resistance is 500 Ω. Load resistances of up to 1000 Ω are possible, however, resistance values greater than 500 Ω can interfere with the HART communication.A process control system or a PC can be connected via a RS 485 interface (terminals 13, 14 and 15). Up to 31 KFD2-HMM-16 can be operated on one RS 485 interface. Terminals 19, 20 and 21 can be used to connect additional stations to the RS 485 interface. The DIP-switch on the housing front is for the setting of the RS 485 address and the baud rate.Figure 3: Block diagram of KFD2-HMM-1626 pin connectorfor up to16 analog signal sources 14 pin connector for up to 15 KFD0-HMS-16 devicesFigure 4: Block diagram of KFD2-HMS-16The HART multiplexer KFD2-HMM-16 (KFD0-HMS-16) has only one de-coupling capacitor for each analog signal as can be seen in Figure 3 and Figure 4, but can be connected to a module interface as shown in Figure 5 to also have the ground de-coupled by a second capacitor. Figure 5: Block diagram HART multiplexer with module interface for loop 1 and 24.2 2700 HART Signal MultiplexerThe Mux2700 HART Multiplexer provides 32 signal channels for connection to “smart” transmitters or control devices supporting digital communication according to the HART standard.Two Decoupling Capacitors are provided, one for each signal connection.Both + Ve (positive) & - Ve (negative) signal wires are therefore decoupled from DC signal. Only the high frequency digital HART protocol signal passes through to the internal Multiplexer circuitry.It acts as a gateway between a workstation - typically a PC - and the field instrumentation.Each Mux2700 is networked simply by connecting the high-speed RS485 output in multidrop configuration. The Mux2700 interrogates each field device, under the supervision of the workstation, retrieving information for storage in its internal database, which can then be accessed at ease.Figure 6: Block diagram of 2700 HART Signal Multiplexer5 Failure Modes, Effects, and Diagnostics Analysis5.1 Description of the failure categoriesThe fail-safe state is defined as the HART multiplexer is not communicating.Failures are categorized and defined as follows:A safe failure (S) is defined as a single failure that causes the HART multiplexer not to communicate.A dangerous failure (D) is defined as a single failure that disturbs the safety system connected to the HART multiplexer.A “don't care” failure (#) is defined as a single failure of a component that is part of the safety function but has no effect on the safety function of the module / (sub)system.5.2 Methodology – FMEDA, Failure rates5.2.1 FMEDAA Failure Modes and Effects Analysis (FMEA) is a systematic way to identify and evaluate the effects of different component failure modes, to determine what could eliminate or reduce the change of failure, and to document the system in consideration.An FMEDA (Failure Mode Effect and Diagnostic Analysis) is an FMEA extension. It combines standard FMEA techniques with extension to identify online diagnostics techniques and the failure modes relevant to safety instrumented system design. It is a technique recommended to generate failure rates for each important category (safe detected, safe undetected, dangerous detected, dangerous undetected, fail high, fail low) in the safety models. The format for the FMEDA is an extension of the standard from MIL STD 1629A, Failure Modes and Effects Analysis.5.2.2 Failure ratesThe failure rate data used by in this FMEDA are from the Siemens SN 29500 failure rate database. The rates were chosen in a way that is appropriate for safety integrity level verification calculations. It is expected that actual field failure results with average environmental stress will be superior to the results predicted by these numbers.The user of these numbers is responsible for determining their applicability to any particular environment. Accurate plant specific data is preferable to general industry average data. Industrial plant sites with high levels of stress must use failure rate data that is adjusted to a higher value to account for the specific conditions of the plant.5.2.3 AssumptionThe following assumptions have been made during the Failure Modes, Effects, and Diagnostic Analysis of the HART multiplexer.• Failure rates are constant, wear out mechanisms are not included.• Propagation of failures is not relevant.• All component failure modes are known.• The repair time after a safe failure is 8 hours.• The average temperature over a long period of time is 40°C.• The stress levels are average for an industrial environment.• All modules are operated in the low demand mode of operation.• Only one communication line is considered to be part of the safety function.6 Results of the assessment did the FMEDAs supported by Pepperl+Fuchs.The analysis has shown that only a couple of components of the HART multiplexer can be found where potentially dangerous failure exist. All other component failures can only lead to the defined safe state but can never disturb the connected safety-related system. The following critical points were identified:1. Short circuits (to ground, to power or between each other) of the signal lines from theinterconnection terminal to the field side of the de-coupling capacitors;2. Short circuit of the de-coupling capacitor.For the calculation of the Safe Failure Fraction (SFF) the following has to be noted:λtotal consists of the sum of all component failure rates. This means:λtotal = λsafe + λdangerous + λdon’t care2SFF = 1 – λdu / λtotalFor the FMEDAs the following failure modes and below mentioned distributions were used. Capacitor fixed plastic (in accordance with [N3])Failure Mode Distribution (in %)Short 40 Open 42 Change in value 182 These are all failures that have no impact on the safety function. The behavior of the system is neither dangerous nor safe.Capacitor Al-ELKO (in accordance with [N3]) Failure ModeDistribution (in %)Short 38 Open 31 Seal failure31For the calculation of the PFD the following Markov models for a 1oo1 and 1oo2 architecture were used. As there are no explicit on-line diagnostics, no state “dd” – dangerous detected is required. As after a complete proof all states are going back to the OK state no proof rate is shown in the Markov models but included in the calculation.The proof time was changed using the Microsoft® Excel 2000 based FMEDA tool of as a simulation tool. The results are documented in the following sections.Figure 7: Markov model for a 1oo1 architectureAbbreviations: d The system has failed dangerous s The system has failed safe λd Failure rate of dangerous failures λs Failure rate of safe failures βCommon cause factor (set to 5%)T Repair Repair time τRepair Repair rate (1 / T Repair )Figure 8: Markov model for a 1oo2 architecture6.1 KFD2-HMM-16 and KFD0-HMS-16Item 1. of the critical points identified in section 6 can be excluded according to draft IEC 60947-5-3 A.1.2 if:• The HART multiplexer are mounted in a housing of minimum IP 54• The base material used is according to IEC 60249, the design and use of the printed board is according to IEC 60326 T3 and the creepage distances and clearances are designed according to IEC 60664-1 (1992) with pollution degree 2 / installation category III, or• The printed side(s) are coated with an insulation material in accordance to IEC 60664-3 (1992)Clearances and creepage distances according to IEC 60661-1 with pollution degree 2 / installation category II for a nominal voltage of 24 VDC are given in Table 4.Table 4: Clearances and creepage distances according to IEC 60661-1Clearances (table 2) Creepage distances (table 4) Printed wiring material 0,1 mm 0,04 mmAccording to Pepperl+Fuchs the base material used is according to IEC 60249 and the minimum creepage distances and clearances are 0,15 mm. This is considered to be sufficient as the interesting distances are part of an energy-consuming equipment supplied from fixed installation, i.e. installation category II. In addition the HART multiplexer is not a safety critical system itself but is connected to one. Thus there are no to special requirements with regard to reliability and availability (see section 2.2.2.1.1 of IEC 60664-1) and installation category III does not apply.Item 2. of the critical points identified in section 6 was analyzed in form of a FMEDA under the assumptions described in section 5.2.3 and 6.The following failure rates and SFF were calculated for the de-coupling capacitor:λtotal = 7,00E-10 1/hλsafe = 2,94E-10 1/hλdangerous = 2,80E-10 1/hλdon’t care = 1,26E-10 1/hSFF = 60,00% (HFT = 0)NOTE: As all faults of the additional electronic will either contribute to λsafe or λdon’t care with regard to the interference freeness on the 4..20mA signal the failure modes of the different components were not explicitly analyzed and are not part of the above mentioned failure rates.The PFD was calculated for three different proof times using the Markov model as described in Figure 7.T[Proof] = 1 year T[Proof] = 5 years T[Proof] = 10 yearsPFD AVG = 1.23E-06PFD AVG = 6.13E-06PFD AVG = 1.23E-05than 10% of this range, i.e. to be better than or equal to 10-3. The PFD values even fulfill the requirements of higher SILs but the system does only fulfill the architectural constraints requirements (HFT/SFF) for SIL 2 which are set by table 2 of IEC 61508-2 for type A components having a hardware fault tolerance of 0.The following figure shows the result of the PFD calculation for T[Proof] = 1 year.Figure 9: PFD for T[Proof] = 1 yearIf the HART multiplexer KFD2-HMM-16 and KFD0-HMS-16 are used together with the module interface as described in section 4.1 then two de-coupling capacitors have to fail to bring the (sub)system into a dangerous state. This corresponds to a hardware fault tolerance of 1.The PFD was calculated for three different proof times using the Markov model as described in Figure 8.T[Proof] = 1 year T[Proof] = 5 years T[Proof] = 10 yearsPFD AVG = 6.13E-08PFD AVG = 3.07E-07PFD AVG = 6.13E-07than 10% of this range, i.e. to be better than or equal to 10-4. The PFD values even fulfill the requirements of a higher SIL but the system does only fulfill the architectural constraints requirements (HFT/SFF) for SIL 3 which are set by table 2 of IEC 61508-2 for type A components having a hardware fault tolerance of 1.The following figure shows the result of the PFD calculation for T[Proof] = 1 year and β = 5% (maximum common cause factor for a logic sub-system according to IEC 61508-6).Figure 10: PFD for T[Proof] = 1 year and β = 5%6.2 2700 HART Signal MultiplexerItem 1. of the critical points identified in section 6 can be excluded according to draft IEC 60947-5-3 A.1.2 if:• The HART multiplexer are mounted in a housing of minimum IP 54• The base material used is according to IEC 60249, the design and use of the printed board is according to IEC 60326 T3 and the creepage distances and clearances are designed according to IEC 60664-1 (1992) with pollution degree 2 / installation category III, or• The printed side(s) are coated with an insulation material in accordance to IEC 60664-3 (1992)Clearances and creepage distances according to IEC 60661-1 with pollution degree 2 / installation category II for a nominal voltage of 24 VDC are given in Table 5.Table 5: Clearances and creepage distances according to IEC 60661-1Clearances (table 2) Creepage distances (table 4) Printed wiring material 0,1 mm 0,04 mmAccording to Pepperl+Fuchs the base material used is according to IEC 60249 and the minimum creepage distances and clearances are 0,25 mm. This is considered to be sufficient as the interesting distances are part of an energy-consuming equipment supplied from fixed installation, i.e. installation category II. In addition the HART multiplexer is not a safety critical system itself but is connected to one. Thus there are no to special requirements with regard to reliability and availability (see section 2.2.2.1.1 of IEC 60664-1) and installation category III does not apply.Item 2. of the critical points identified in section 6 was analyzed in form of a FMEDA under the assumptions described in section 5.2.3 and 6.The following failure rates and SFF were calculated for the two de-coupling capacitors: λtotal = 3,70E-09 1/h λsafe = 1,22E-09 1/h λdangerous = 1,42E-09 1/h λdon’t care = 1,06E-09 1/h SFF = 61,62% (HFT = 1)NOTE: As all faults of the additional electronic will either contribute to λsafe or λdon’t care with regard to the interference freeness on the 4..20mA signal the failure modes of the different components were not explicitly analyzed and are not part of the above mentioned failure rates. As two de-coupling capacitors have to fail to bring the (sub)system into a dangerous state a hardware fault tolerance of 1 is considered.The PFD was calculated based on the failure rate of the Al-ELKO as a worst case assumption for three different proof times using the Markov model as described in Figure 8.T[Proof] = 1 yearT[Proof] = 5 yearsT[Proof] = 10 yearsPFD AVG = 2.50E-07PFD AVG = 1.25E-06PFD AVG = 2.50E-06than 10% of this range, i.e. to be better than or equal to 10-4. The PFD values even fulfill the requirements of a higher SIL but the system does only fulfill the architectural constraints requirements (HFT/SFF) for SIL 3 which are set by table 2 of IEC 61508-2 for type A components having a hardware fault tolerance of 1.The following figure shows the result of the PFD calculation for T[Proof] = 1 year and β = 5% (maximum common cause factor for a logic sub-system according to IEC 61508-6).Figure 11: PFD for T[Proof] = 1 year and β= 5%7 Terms and DefinitionsFMEDA Failure Mode Effect and Diagnostic AnalysisHFT Hardware Fault ToleranceLow demand mode Mode, where the frequency of demands for operation made on a safety-related system is no greater than one per year and no greater than twicethe proof test frequency.λtotal Total failure rate λ (overall failure rate of all components)λsafe Failure rate λ of all safe failuresλdangerous Failure rate λ of all dangerous failuresλdu Failure rate λ of dangerous undetected failuresPFD Probability of Failure on DemandPFD AVG Average Probability of Failure on DemandSFF Safe Failure Fraction summarizes the fraction of failures, which lead to a safe state and the fraction of failures which will be detected bydiagnostic measures and lead to a defined safety action.SIF Safety Instrumented FunctionSIL Safety Integrity LevelSIS Safety Instrumented System8 Status of the document8.1 Liability prepares FMEDA reports based on methods advocated in International standards. Failure rates are obtained from a collection of industrial databases. accepts no liability whatsoever for the use of these numbers or for the correctness of the standards on which the general calculation methods are based.8.2 ReleasesVersion: V1Revision: R1.2Version History: V0, R1.0: Initial version, June 19, 2002V0, R1.1: Failure rates for the de-coupling capacitors of the MUX 2700corrected; section 2.3.2 completed; failure modes of Al-ELKO insection 6 added; June 24, 2002V1, R1.0: Comments after review integrated, June 27, 2002V1, R1.1: Management summary corrected; section “Purpose and Scope”modified, June 28, 2002V1, R1.2: Management summary changed; section “Purpose and Scope”modified, July 3, 2002AschenbrennerAuthors: StephanReview: V0, R1.0: Werner Bansemir (P+F), June 24, 2002V0, R1.1: Peter Müller (), June 26, 2002Release status: released to Pepperl+Fuchs8.3 Release SignaturesDipl.-Ing. (Univ.) Stephan Aschenbrenner, Senior Project ManagerDipl.-Ing. (Univ.) Rainer Faller, Principal Partner。
MPPT控制面板用户手册说明书
ESPAÑOL Manual de la pantalla MPPTControlRev 00 04/2021Este manual también está disponible en formato HTML5.Tabla de contenidos1. Introducción (1)2. Montaje (3)3. Instalación (5)4. Funcionamiento (7)4.1. Menú estado (8)4.2. Menú histórico (8)4.3. Menú de ajustes (10)5. Resolución de problemas y asistencia (13)5.1. Problemas de potencia (13)5.2. Ajustes bloqueados (13)6. Garantía (14)7. Especificaciones (15)La pantalla MPPT Control es una pantalla específica para la gama de cargadores solares MPPT SmartSolar y BlueSolar de MPPT de Victron Energy. Puede usarse para leer los datos históricos y en tiempo real del cargador solar y para configurarlo. Ejemplos de seguimiento en tiempo real e histórico:•Potencia FV, rendimiento, tensión y corriente.•Tensión, corriente y estado de carga de la batería.•Estado y corriente de la salida de carga (solo disponible si el cargador solar cuenta con salida de carga).•Valores históricos de 30 días•Valores históricos acumulados a lo largo de la vida del cargador solarPantalla MPPT ControlCable de alimentaciónLa pantalla viene con un cable de alimentación con fusible.El cable de alimentación proporcionado solo se necesita cuando la pantalla se usa con algunos modelos de cargador solar antiguos que llevan tiempo descatalogados. Estos modelos antiguos se apagan cuando no reciben energía solar. El cable de alimentación lleva energía a la pantalla directamente desde la batería de modo que la pantalla también funciona si hace mal tiempo o una vez que el sol se ha puesto.Cable de alimentaciónCable VE.DirectSe necesita un cable VE.Direct para conectar la pantalla al cargador solar. Este cable no se incluye con la pantalla MPPT Control y debe comprarse por separado.Puede encontrar los cables VE.Direct en longitudes de entre 0,3 y 10 metros y con conectores rectos y en ángulo. Para más información, consulte la página de producto de cable VE.Direct.Cable VE.DirectCarcasa para montaje en paredLa carcasa de la pantalla MPPT Control está diseñada para montarse empotrada en el panel. En caso de que no pueda montarse empotrada, se puede usar una carcasa específica para montaje en la pared. Esta carcasa permite montar fácilmente la pantalla en la pared.Hay dos opciones de montaje en la pared:•Carcasa de montaje en la pared para BMV o MPPT Control•Carcasa de montaje en la pared para BMV y Color Control GXCarcasa de montaje en la pared para BMV o MPPT ControlHaga un orificio con un taladro en un sustrato de montaje como se indica en la siguiente figura.Anchura y profundidad que ha de tener la cavidad de montaje Monte la pantalla:Use la opción A si puede acceder al sustrato de montaje desde los dos lados.Use la opción B si puede acceder al sustrato de montaje por la parte frontal.12Opción de montaje A12345Opción de montaje BConecte el cargador solarConecte la pantalla MPPT Control al cargador solar con el cable VE.Direct.No se puede alargar el cable VE.Direct, la longitud máxima no puede superar los 10 metros.Parte trasera de la pantalla MPPT Control con las conexiones de alimentación y VE.Direct.Conecte la pantalla al cargador solar con el cable VE.Direct.Conecte el cable de alimentación (solo se necesita con controladores solares antiguos)El cable de alimentación proporcionado solo se necesita cuando la pantalla se usa con algunos modelos decargador solar antiguos que llevan tiempo descatalogados.Conecte el cable de alimentación como sigue:•Conecte la anilla del cable negro al polo negativo de la batería. Si el sistema tiene un monitor de batería, entonces conecte el cable negro a la parte del sistema del derivador del monitor de batería.•Conecte la anilla del cable rojo al polo positivo de la batería.•Enchufe el conector RJ12 en el conector de alimentación de la parte trasera de la pantalla.Conecte la pantalla a un modelo antiguo de cargador solar y a la bateríaLa pantalla LCD muestra la siguiente información:•Una lectura numérica.•La unidad de la lectura: V, A, W, kWh, h o !•El tipo de lectura: carga, batería, FV, mín, máx. o estado de carga.•Indicador del estado de la conexiónLectura completa LCDLos dígitos usados representan letras y númerosEl estado de conexión de la pantalla se indica con un símbolo de “flecha doble” tal y como figura en la tabla siguiente.Los botones de la parte frontal de la pantalla se usan para desplazarse por las lecturas del cargador solar y para hacer ajustes en el controlador solar y en la pantalla. Tienen las funciones siguientes:4.1. Menú estadoEste menú muestra las lecturas del cargador solar en tiempo real. La pantalla MPPT Control siempre se inicia con este menú. Pulse los botones que indican abajo y arriba para moverse por todos los elementos del menú.Estos elementos del menú se mostrarán en orden de aparición, tal y como se indica en la tabla siguiente:4.2. Menú históricoEl menú histórico muestra los datos históricos diarios y globales del cargador solar. Muestra elementos como el rendimiento solar, las tensiones de la batería, el tiempo dedicado a cada estado de carga y errores anteriores.Para entrar y leer el menú histórico:•Pulse el botón SELECT (seleccionar) desde el menú de estado.•Pulse los botones que indican abajo y arriba para moverse por los elementos del historial.•Cuando llegue al elemento del historial que desea, pulse el botón SELECT (seleccionar) para ver su valor.•Si un elemento contiene varios valores, pulse el botón SELECT (seleccionar) y use los botones de abajo o arriba para ver los distintos valores de ese elemento. En el caso de los valores diarios es posible desplazarse hasta los valores de 30 días atrás (los datos se hacen disponibles con el tiempo). Una pequeña ventana emergente muestra el día correspondiente.•Para volver al menú principal del historial pulse el botón SETUP (configuración).•Para volver al menú de estado pulse el botón SETUP (configuración) de nuevo.Gráfico de navegación del menú históricoTodos los elementos disponibles del menú histórico se recogen en la siguiente tabla en el orden en que aparecen al desplazarse por ellos.4.3. Menú de ajustesEn el menú de ajustes se pueden consultar y modificar los ajustes del cargador solar y del MPPT Control.No cambie los ajustes sin saber qué son y cuáles son las consecuencias de cambiarlos. Los ajustesincorrectos pueden causar problemas en el sistema e incluso dañar las baterías. Si tiene dudas, consultea un instalador, vendedor o distribuidor de Victron Energy con experiencia.Para navegar por el menú de ajustes:•Mantenga pulsado el botón SETUP (configuración) durante 2 segundos para entrar en el menú de ajustes.•Aparecerá el primer elemento del menú.•Diríjase al elemento del menú que quiera pulsando los botones que indican abajo y arriba.•Una vez que haya llegado al elemento que busca, pulse el botón SELECT (seleccionar) para ver el valor fijado en la configuración.•Para modificar este ajuste pulse el botón SELECT (seleccionar) de nuevo. Ahora el valor parpadeará.•Pulse los botones de abajo y arriba para elegir el valor deseado.•Pulse SELECT (seleccionar) para confirmar el cambio, podrá oír un pitido y aparecerá la palabra SAVED (guardado). El cambio se convertirá en definitivo.•Vaya al siguiente elemento del menú o pulse SETUP (configuración) para volver al menú de ajustes.•Para salir del menú de ajustes, pulse el botón SETUP (configuración) de nuevo.Es posible que el menú de ajustes esté bloqueado, y en ese caso la configuración solo podrá verse. Al intentar modificar un ajuste, aparece la palabra LOCK (bloqueo).Para desbloquear el menú de ajustes:•Vaya al elemento del menú de ajustes 01 LOCK SETUP (bloquear ajustes).•Pulse el botón SETUP (configuración), aparecerá el ajuste ON•Pulse el botón SETUP (configuración) de nuevo•Pulse el botón de la flecha hacia abajo y seleccione OFF•Para salir del ajuste, pulse el botón SETUP (configuración).Si SELECT TO EDIT (seleccionar para editar) está en ON, se muestra el valor actual y se puede seleccionar un nuevo valor inmediatamente.Si LOCK SETUP (bloquear ajustes) está en ON, la configuración está bloqueada y sólo puede modificarse si se pone LOCK SETUP en OFF.Gráfico de navegación por los ajustes de MPPT ControlEn la tabla siguiente se recogen todos los ajustes disponibles, en el orden en que aparecen al desplazarse por el menú, junto con una breve explicación de cada uno de ellos. Puede consultar la descripción completa de los ajustes del cargador solar en el manual del cargador solar.Es posible que no todos los ajustes indicados a continuación estén disponibles al conectarse a determinados modelos de cargadores solares. Puede que el cargador solar no tenga el hardware necesario. Por ejemplo, no todos los cargadores solares disponen de una salida de carga.Es posible que algunos ajustes no aparezcan en el menú de configuración. La pantalla MPPT Control solo permite cambiar los ajustes más comunes. No se puede acceder a los ajustes más avanzados, como los de los puertos TX y RX, a través de la pantalla MPPT Control. Para configurar estos ajustes use la aplicación VictronConnect o, para cargadores solares de 60 A ymás, use una pantalla SmartSolar Control.Consulte este apartado en caso de que se produzca algún comportamiento inesperado o si sospecha que hay un fallo en el producto.Como parte del proceso de resolución de problemas y asistencia, lo primero es consultar los problemas comunes que se describen en este apartado.Si no consigue resolver el problema de este modo, póngase en contacto con el punto de venta para solicitar asistencia técnica. Si desconoce el punto de venta, consulte la página web de asistencia de Victron Energy.5.1. Problemas de potenciaLa pantalla se alimenta a través del cable VE.Direct o del cable de alimentación. Si no se enciende, revise estos cables. Comprobación del cable VE.Direct:pruebe si el cable VE.Direct está enchufado en la parte trasera de la pantalla.pruebe si el cable VE.Direct está enchufado en el cargador solar.3.Asegúrese de que los conectores VE.Direct están bien metidos en los puertos VE.Direct.pruebe los pines del puerto VE.Direct, asegúrese de que no están dañados o doblados y de que no falta ninguno.pruebe si el cargador solar puede proporcionar alimentación a través del cable VE.Direct cuando no hay entrada FV( por la noche). Algunos modelos de cargador solar antiguos, descatalogados hace tiempo, necesitan que se instale el cable de alimentación.Comprobación del cable de alimentación1.Revise el fusible del cable de alimentación.pruebe si el cable de alimentación está enchufado en la parte trasera de la pantalla.pruebe si el cable de alimentación está conectado a la batería o a otra tensión de alimentación.pruebe si la tensión de alimentación está entre 6,5 y 95 V CC.5.2. Ajustes bloqueadosSi el menú de ajustes está bloqueado, los ajustes pueden verse, pero no modificarse. Al intentar modificar un ajuste, aparece la palabra LOCK (bloqueo).Para desbloquear el menú de ajustes, consulte las instrucciones del apartado Menú de ajustes [10].Este producto tiene garantía limitada durante 5 años. Esta garantía limitada cubre los defectos de materiales y fabricación de este producto durante un periodo de cinco años a partir de la fecha de compra original. Para hacer uso de la garantía, elcliente deberá devolver el producto en el punto de compra junto con el recibo de compra correspondiente. Esta garantía limitada no cubre daños, deterioro o mal funcionamiento derivados de la alteración, modificación, uso inadecuado, no razonable o negligente; de la exposición a humedad excesiva, fuego, embalaje inadecuado, relámpagos, subidas de tensión u otros motivos de fuerza mayor. Esta garantía limitada no cubre daños, deterioro o mal funcionamiento derivados de reparaciones realizadas por personas no autorizadas por Victron Energy. El incumplimiento de las instrucciones recogidas en este manual supondrá la anulación de la garantía. Victron Energy no será responsable por daños consecuentes derivados del uso de este producto. La responsabilidad máxima de Victron Energy bajo esta garantía limitada no excederá el precio de compra real de este producto.。
多乐士工业专用高耐化学清洁地面漆技术参数表说明书
DULUX TRADE HI-CHEM EPOXY ENAMELTECHNICAL DATA SHEETVersion 3 – 2019 AUGUSTTHIS ISSUE SUPERSEDES ALL PREVIOUS PUBLICATIONSPRODUCT DESCRIPTIONSemi-gloss epoxy enamel for interior industrial and home use (e.g. garage floors, etc.)PRODUCT USES·Can be applied on walls, floors and suitably primed metal surfaces.FEATURES AND BENEFITS·Good resistance to a wide range of chemicals and most solvents.·Cures to a hard film with good adhesion and abrasion resistance.·Provides an economical alternative to tiling in bathrooms, showers, kitchens, toilets and low cost housing.·Suitable for surfaces that require frequent cleaning with solvents, detergents or alkaline cleaners.·The cured film is non-toxic. When properly applied and cured, the product is completely safe for direct or accidental food contact on floor and wall applications.PRODUCT INFORMATIONAppearance Semi- glossColour White, Light Grey, Dark Grey and Brilliant GreenBinder Type Polyamide cured EpoxyDensity at 23°C Approx. 1.30Solids Content By weight: Approx. 60%By volume: Approx. 44%Packaged Viscosity Viscosity at 23°C: Approx. 70 KUSpreading Rate at 35µm DFT Brush: Approx. 9 m² per litre, depending on surface porosity,profile and application methodRecommended DFT per coat Min. 50µm. Max. 60µm.Recommended WFT per coat Min. 110µm. Max. 140µm(Higher film build will increase resistance)Flash Point25ºCDULUX TRADE HI-CHEM EPOXY ENAMELAPPLICATION INFORMATIONMixing Stir the Base and Curing Agent separately untilhomogeneous with a flat paddle. Then add the Curing Agentto the Base and stirring until homogeneous with a flat paddle Mixing Ratio 4 parts Base to 1 part Curing Agent by volume.Application Surface conditions Surface Temperature between 10 - 35°C. Relative Humiditybetween 10 - 85 % OR 2ºC above dew point minimum. Application methods Dulux Trade Hichem Epoxy Enamel is packaged in twocomponents in the proper proportions which must be mixedtogether until homogenous before use. See MixingAirless Spray: Ready for use after induction period of 30minutes.Air Spray: After mixing, thin 10% by volume and allowinduction period of 30 minutes.Brush: Can be used on small areas where joining is not aproblem e.g. signs, pipes, colour bands, etc.Roller: Short nap roller may be used on tanks and silostaking precautions to pick up the wet edge to avoid “window-paning”.Self-Priming on porous masonry: The product can only beover coated with itself. If a primer is required,Dulux TradeHichem Epoxy Enamel thinned 10% by volume can beutilised as a primer coat.N.B. Mix the paint first, then stir in the thinners.Thinner Dulux Trade Heavy Duty Thinners for spraying tomaximum of 10% of product volume and should only beadded after mixing the Curing Agent with the Base andstirred homogeneous with a flat paddle.Induction Period30 minutes at 25°C (i.e. do not paint immediately aftermixing).Pot Life to gelation Approx. 8 hours at 25°CDrying Time Dry to handle: 24 hours at 25ºC.Recoating Time 6 hours minimum; up to 7 days maximum at 25°C. (Dryingtimes will be extended during cold, wet or humid conditions.)APPLICATION INFORMATIONCleaning of equipment After use, remove as much product as possible, and thenclean immediately with Dulux Trade Heavy Duty Thinners. Substrates Correctly prepared cement plaster, concrete and correctlyprepared and primed mild steel and ironDULUX TRADE HI-CHEM EPOXY ENAMELAPPLICATION INFORMATIONPrecautions:Do not apply during cold (below 10°C) or wet weather.Do not apply directly to bare metal surfaces.Recommended for interior surfaces only, as the film willchalk on exterior exposure.Cure is slow at low temperatures; below 15°C it takes somedays to reach handling and recoating hardness.The pot life is short above 35°C; shield pressure pots andfluid lines from direct sun.Equipment and brushes must be cleaned immediately.Heat resistant to + 120°C (continuous) although someyellowing occurs above 100°C.Not suitable for direct application to powdery or friablesurfaces whether previously painted or not.Coats Required Apply two to three finishing coats to new surfaces to achievea minimum continuous film of 70µm microns to produceclosed film and solid colour.For non-skid pedestrian areas, three full coats will berequired. See “SURFACE PREPARATION”.SURFACE PREPARATIONEnsure that surfaces are sound and free from dust, oil, grease, dirt, and debris. Surfaces must be thoroughly dry - no more than 12% moisture content.NEW SURFACESCement Plaster, Concrete (non-friable)·Freshly rendered concrete should have dried/cured for a minimum of 6 weeks, the moisture content of the concrete should be below 12% before any preparation andpainting is attempted.·It is recommended that fresh plaster should be allowed 1 week drying for every 5mm thickness; and longer in cold or damp weather.·Ensure the entire surface is sound and clean. Remove any plaster spills, and all loose debris from the surface, ensuring an even and clean surface.·Acid etch the surface with a solution of hydrochloric acid to remove laitance, uncured cement, etc. as follows: On steel or power floated concrete (very smooth), use onevolume hydrochloric acid to two volumes water. More than one application may benecessary to achieve a paintable surface. On wood floated concrete (rough), use one volume hydrochloric acid to four volumes water.N.B. Hydrochloric acid is corrosive -please wear protective clothing, gloves, masks and eye goggles against splashes.·Allow the acid solution to react for 15 minutes and then wash away all acid with copious amounts of clean water.·Remove excess water and allow thorough drying–no more than 12% moisture content.DULUX TRADE HI-CHEM EPOXY ENAMELSURFACE PREPARATIONNEW SURFACESFloors Concrete – NON-SKID Pedestrian areas (walkways and passages)·Follow the cleaning and etching instructions under surface preparation, new surfaces, Cement Plaster, Concrete (non-friable)·Coat 1 – Apply and, while it is still wet, sprinkle dry, silica sand over the surface. (The silica sand should be sifted through a 250µm sieve and retained on a 210µm sieve. A practical spreading rate is 500 grams of sand per square meter of painted floor.)·Coat 2 - The following day, sweep off any excess sand and apply a further coat to seal the surface. Allow overnight drying again·Coat 3 – Apply 3rd coat·Observe chemical curing times as stated in this technical data sheet.Mild Steel and Iron·Remove all shop-primer and corrosion products from the steel. Sand blast steel to achieve a bright metal condition, and a cleanliness standard of Sa2½ minimum.·Clean bare steel with a solvent wash (rags dipped in lacquer thinner). Change rags frequently.·Apply one or two coats Dulux Trade Corrocote 1 Metal Etch Primer, depending on the severity of the conditions. Two coats are preferred for coastal conditions. PREVIOUSLY PAINTED SURFACES·The existing coating system should be dry and free of contaminants such as oil, grease and loose paint.·Test that the surface will accept epoxy by allowing a cloth soaked with Dulux Trade Heavy Duty Thinners to rest on it for 15 minutes - it must not lift or wrinkle. If lifting or wrinkling occurs, the paint must be removed with paint stripper or any other suitable means.·Abrade damaged or failed areas back to a sound substrate and treat as new.·Aged or weathered epoxies or urethanes must be well sanded to a matt finish to providea profile for adhesion.DULUX TRADE HI-CHEM EPOXY ENAMELHEALTH AND SAFETY INFORMATIONSolvent based paints are flammable.This product contains no added lead. Avoid contact with skin or eyes. Keep out of reach of children. If accidently swallowed, seek medical advice immediately and show this container to the doctor. Dry sanding, flame cutting and/or welding of the dry paint film will give rise to dust and/or hazardous fumes. Wet sanding should be used wherever possible.If exposure cannot be avoided by the provision of local exhaust ventilation, suitable respiratory protective equipment should be used. Do not empty into drains or watercourses. Ensure good ventilation during application and drying. It is recommended to use suitable protective clothing and equipment. To avoid the risk of spillage, always store and transport containers in a secure upright position. Refer to Material Safety Data Sheet for complete information.ADDITIONAL INFORMATIONPackaging 5 Litre (4L base in large tin, 1L curing agent).Storage Conditions Store under cool dry conditions away from direct sunlight,heat and extreme cold.Disclaimers Colour references are as accurate as modern printing willallow. Please refer to colour cards for an accuraterepresentation of the colour.Among others, the following factors may affect final colourappearance: product sheen and texture, colour and lightreflections, application, surface texture and preparation.For best colour and sheen consistency, it is advisable to usecontainers of the same batch number, to mix differentbatches together in a large container, or to finish in a cornerbefore starting a new container.TDS STANDARD DISCLAIMERThe recommendations contained herein are given in good faith and meant to guide the specifier or user in accordance with good painting practices. They are gained from our tests and experiences and are believed to be accurate and reliable. No warranty/guarantee is implied by the recommendations contained herein since the conditions of use; application method, substrate and cleanliness of the substrate are beyond Dulux control.Important Note; Technology may change with time, necessitating changes to this Technical Data Sheet (TDS).It is the responsibility of the user to ensure that the latest TDS is being used for reference. Dulux Technical Data Sheets are available on our website www.duluxtrade.co.za or please contact: Dulux On-Line on 0860 330 111. Email*************************ICI Dulux (Pty) Ltd is part of AkzoNobel. ICI Dulux (Pty) Ltd Reg No.1946/020769/07。
安捷伦产品目录
15
Real-Time PCR
16
Mx3000P QPCR System
17
Brilliant III Ultra-Fast SYBR Green QPCR and QRT-PCR Reagents
18
Brilliant III Ultra-Fast QPCR and QRT-PCR Reagents
Agilent / STRATAGENE
Agilent website: /genomics
Welgene | Agilent Stratagene
威健股份有限公司 | Stratagene 總代理
Table of Content
Table of Contents
/ XL1-Red Competent Cells SoloPack Gold Supercompetent Cells
/ TK Competent Cells Specialty Cells
/ Classic Cells / Fine Chemicals For Competent Cells
適用於 UNG 去汙染或 bisulphite
sequencing
適用於 TA Cloning
最高敏感性
取代傳統 Taq 的好選擇
-
2
威健股份有限公司 | Stratagene 總代理
PCR Enzyme & Instrument
Agilent SureCycler 8800
市場上領先的 cycling 速度和 sample 體積 10 ～ 100 μL 簡易快速可以選擇 96 well 和 384 well 操作盤 優秀的溫控設備讓各個 well 都能保持溫度的穩定 七吋的高解析度觸控螢幕讓操作上更為簡便 可以透過網路遠端操控儀器及監控儀器 Agilent 專業的技術支援可以幫助您應對各種 PCR 的問題
特碳17-40B-PD 产品数据单据说明书
Product Data SheetTrigonox 17-40B-PD Butyl 4,4-di(tert-butylperoxy) valerateTrigonox® 17-40B-PD is a 40% formulation on an inert carrier system in powder form.CAS number995-33-5EINECS/ELINCS No.213-626-6TSCA statuslisted on inventoryMolecular weight334.5Active oxygen contentperoxide9.57%Concentration3.73-3.92%SpecificationsAppearance Off-white powderAssay39.0-41.0 %ApplicationsTrigonox® 17-40B-PD is a bifunctional peroxide which is used for the crosslinking of natural rubber and synthetic rubbers, as well as polyolefins. Safe processing temperature: 125°C (rheometer ts2 > 20 min.). Typical crosslinking temperature: 160°C (rheometer t90 about 12 min.).Thermal stabilityOrganic peroxides are thermally unstable substances, which may undergo self-accelerating decomposition. The lowest temperature at which self-accelerating decomposition of a substance in the original packaging may occur is the Self-Accelerating Decomposition Temperature (SADT). The SADT is determined on the basis of the Heat Accumulation Storage Test.SADT60°CMethod The Heat Accumulation Storage Test is a recognized test method for thedetermination of the SADT of organic peroxides (see Recommendations on theTransport of Dangerous Goods, Manual of Tests and Criteria - United Nations, NewYork and Geneva).StorageDue to the relatively unstable nature of organic peroxides a loss of quality can be detected over a period of time. To minimize the loss of quality, Nouryon recommends a maximum storage temperature (Ts max. ) for each organic peroxide product.Ts Max.30°CNote When stored under the recommended storage conditions, Trigonox® 17-40B-PDwill remain within the Nouryon specifications for a period of at least 6 months afterdelivery.Packaging and transportThe standard packaging is a cardboard box for 25 kg peroxide formulation. Both packaging and transport meet the international regulations. For the availability of other packed quantities consult your Nouryon representative. Trigonox®17-40B-PD is classified as Organic peroxide type E; solid, Division 5. 2; UN 3108.Safety and handlingKeep containers tightly closed. Store and handle Trigonox® 17-40B-PD in a dry well-ventilated place away from sources of heat or ignition and direct sunlight. Never weigh out in the storage room. Avoid contact with reducing agents (e. g. amines), acids, alkalines and heavy metal compounds (e. g. accelerators, driers and metal soaps). Please refer to the Safety Data Sheet (SDS) for further information on the safe storage, use and handling of Trigonox® 17-40B-PD. This information should be thoroughly reviewed prior to acceptance of this product. The SDS is available at /sds-search.Major decomposition productsMethane, Carbon dioxide, Acetone, tert-Butanol, n-Butyl propionate,All information concerning this product and/or suggestions for handling and use contained herein are offered in good faith and are believed to be reliable.Nouryon, however, makes no warranty as to accuracy and/or sufficiency of such information and/or suggestions, as to the product's merchantability or fitness for any particular purpose, or that any suggested use will not infringe any patent. Nouryon does not accept any liability whatsoever arising out of the use of or reliance on this information, or out of the use or the performance of the product. Nothing contained herein shall be construed as granting or extending any license under any patent. Customer must determine for himself, by preliminary tests or otherwise, the suitability of this product for his purposes.The information contained herein supersedes all previously issued information on the subject matter covered. The customer may forward, distribute, and/or photocopy this document only if unaltered and complete, including all of its headers and footers, and should refrain from any unauthorized use. Don’t copythis document to a website.Trigonox® is a registered trademark of Nouryon Functional Chemicals B.V. or affiliates in one or more territories.Contact UsPolymer Specialties Americas************************Polymer Specialties Europe, Middle East, India and Africa*************************Polymer Specialties Asia Pacific************************2022-6-30© 2022Polymer crosslinking Trigonox 17-40B-PD。
海卓帕特 WE 3323 EC 安全技术说明书
安全技术说明书页: 1/10 巴斯夫安全技术说明书按照GB/T 16483编制日期 / 本次修订: 09.05.2023版本: 1.0日期/上次修订: 不适用上次版本: 无日期 / 首次编制: 09.05.2023产品: 海卓帕特 WE 3323 ECProduct: Hydropalat® WE 3323 EC(30797308/SDS_GEN_CN/ZH)印刷日期 04.11.20231. 化学品及企业标识海卓帕特 WE 3323 ECHydropalat® WE 3323 EC推荐用途和限制用途: 表面活性剂, 润湿剂, 墨水,清漆或涂料用添加剂公司:巴斯夫(中国)有限公司中国上海浦东江心沙路300号邮政编码 200137电话: +86 21 20391000传真号: +86 21 20394800E-mail地址: **********************紧急联络信息:巴斯夫紧急热线中心（中国）+86 21 5861-1199巴斯夫紧急热线中心（国际）:电话: +49 180 2273-112Company:BASF (China) Co., Ltd.300 Jiang Xin Sha RoadPu Dong Shanghai 200137, CHINA Telephone: +86 21 20391000Telefax number: +86 21 20394800E-mail address: ********************** Emergency information:Emergency Call Center (China):+86 21 5861-1199International emergency number: Telephone: +49 180 2273-1122. 危险性概述纯物质和混合物的分类:对水环境的急性危害: 分类3对水环境的慢性危害: 分类3巴斯夫安全技术说明书日期 / 本次修订: 09.05.2023版本: 1.0产品: 海卓帕特 WE 3323 ECProduct: Hydropalat® WE 3323 EC(30797308/SDS_GEN_CN/ZH)印刷日期 04.11.2023标签要素和警示性说明:危险性说明:H402对水生生物有害。
Advanced Materials 200517
Adv.Mater.2005,17,2521www.advmat.de©2005WILEY-VCH Verlag GmbH &Co.KGaA,Weinheim2521How to contact us:Editorial Office:Telephone:(+49)6201606235/432Fax:(+49)6201606500E-mail:advmat@wiley-vch.de Reprints:Agnes PetersenTelephone:(+49)6201606218Fax:(+49)6201606500E-mail:advmat@wiley-vch.de Copyright Permission:Telephone:(+49)6201606280Fax:(+49)6201606332E-mail:rights@wiley-vch.de Subscriptions:Telephone:(+49)6201606400Fax:(+49)6201606184E-mail:service@wiley-vch.de Advertising:Fax:(+49)6201606500E-mail:advmat@wiley-vch.de Courier Services:Boschstrasse 12,69469Weinheim,GermanyRegular Mail:Postfach 101161,69451Weinheim,GermanyAdvanced Materials has been publishing the latest progress in materials science for more than 15years.With an indepen-dently assessed ISI Impact Factorof 8.079,Advanced Materials continues to deliver the highest quality research reports every two weeks.It containscarefully selected,top-quality reviews,communications,and research news at the cutting edge of the chemistry and physics of functional materials as well as book reviews,product information,interviews,and a conference calendar.From 2005our new sister journal‘Small ’,the ideal forum for presenting the very best experimental andtheoretical studies of fundamental and applied research at the micro and nano scales,is being delivered monthly with Advanced Materials .www.advmat.deCover:The automated synthesis and nano-mechanical characterization of discrete combinatorial arrays of polymersenables high-throughput discovery and analysis of compliant,functional materi-als,as shown by Van Vliet and co-work-ers on p.2599.The cover illustrates a triplicate array of 576polymers auto-matically printed on a glass microscope slide,where each spot represents a pair-wise,systematically varied composition among 24different monomers.Overlaid on the image of this triplicate array is a differential interference contrast image of a single nanoliter-scale polymer vol-ume.In less than twenty-four hours of synthesis and mechanical characteriza-tion,the stiffness of each polymer is de-termined and related to key monomer structures and volume fractions thereof.Inside Cover:Short,single-particle-wide chains and complex networks of interconnected chains are easily self-assembled from 13nm Au nanoparticles by inducing a surface electrostatic dipolar moment in a controlled manner.Mann andco-workers further demonstrate both experimentally and theoretically on p.2553that efficient surface plasmon coupling takes place in these extensive networks,thus opening a new bottom–up approach to subwavelength optical-waveguiding devices.The left panel in the image shows isolated 13nm Au nanoparticles;the back panel,short linear chains;the bottom panel,com-plex branched network of chains;and the right panel,a graphical rendering of optical spectroscopic properties during the self-assembly process.Editor:Esther Levy Deputy Editor:Karen Grieve Associate Editors:David Flanagan,Cara Mulcahy,Soraya ReidenbachAssistant Editors:Mary Farrell,Lisa WylieProduction:Agnes Petersen Administration:Ramona Nily,Melanie Schmitt,Susanne StollMarketing:Claudia Barzen Freelance Cartoonist:Philip Harms Editorial Office:Tel.(+49)6201606235/432Fax (+49)6021606500E-mail:advmat@wiley-vch.de Subscription Service:Tel.(+49)6201606400Fax (+49)6021606184E-mail:service@wiley-vch.de Order through your bookseller or directly at the Publisher:Wiley-VCH,P .O.Box 101161,D-69451Weinheim,Germany.Tel.(+49)6201606400Fax (+49)6201606184E-mail:service@wiley-vch.de Published 24times a year by WILEY-VCH Verlag GmbH &Co.KGaAD-69469Weinheim,GermanyAdvisory Board P .M.Ajayan,Rensselaer Polytechnic Inst.P .Batail,Angers M.T.Bernius,DowP .W.M.Blom,GroningenP .D.Calvert,Univ.of Massachusetts J.Caro,HannoverJ.H.Fendler,Clarkson S.Forrest,Princeton R.H.Friend,Cambridge R.C.Haddon,UC Riverside P .T.Hammond,MIT A.Hirsch,Erlangen H.van Houten,Philips J.Hulliger,BernT.Hyeon,Seoul Natl.Univ.A.C.Jones,Inorgtech D.L.Kaplan,Tufts T.Kato,Tokyohav,Weizmann Inst.Sci.S.Mann,BristolC.R.Martin,Univ.of Florida R.D.McCullough,Carnegie MellonE.W.Meijer,Eindhoven ler,UtahC.A.Mirkin,Northwestern W.S.Rees,Georgia Tech J.Rieger,BASFM.J.Sailor,UC San Diego F.Schüth,MPI Mülheim Y.Shirota,FukuiM.Steigerwald,Columbia S.Subramoney,DuPont G.Wegner,MPI MainzBooks for review:Uninvited copies not chosen for review will not be returned.Manuscript Submission &PersonalHomepage:Typeset by kühn &weyhSatz und Medien,Freiburg,Germany.Printed by Druckhaus Darmstadt GmbH,Darmstadt,Germany.Printed on acid-free paper.©2005Wiley-VCH Verlag GmbH &Co.KGaA,D-69469Weinheim,Germany.All rights reserved (including those of translation into foreign languages).No part of this issue may be reproduced in any form –by photoprint,microfilm,or any other means –nor transmitted or translated into a machine language without written permission from the publishers.Only single copies of contribu-tions,or parts thereof,may be made for personal use.This journal was carefully produced in all its parts.Nevertheless,authors,editors,and publisher do not guarantee the information contained therein to be free of errors.Registered names,trademarks,ed in this journal,even when not marked as such,are not to be considered unprotected by law.Valid for users in the USA:The copyright owner agrees that copies of the articles may be made for personal or internal use,or for the personal or inter-nal use of specific clients.This consent is given on the condition,however,that the copier pay the stat-ed per-copy fee through the Copyright Clearance Center,Inc.(CCC)for copying beyond that per-mitted by Sections 107or 108of the U.S.Copyright Law.This consent does not extend to other kinds of copying,such as copying for general distribtion,for advertising or promotional purposes,for creating new collective works,or for resale.For copying from back volumes of this journal see ‘Permissions to Photo Copy:Publisher’s Fee List’of theCCC.Annual subscription rates 2006PersonalInstitutional*Europe EUR 298EUR 3078/3386Switzerland SFr 638SFr 4818/5300Outside EuropeUS$418US$3958/4354*Print or electronic delivery/print +electronic delivery First-time personal rates are available on request.10%discount if ordered in combination with Advanced Functional Materials.Postage and handling charges included.For the USA and Canada:ADVANCED MATERIALS (Print ISSN 0935-9648,Online ISSN 1521-4095)is published semimonthly by Wiley-VCH,P .O.Box 101161,D-69451Weinheim,Germany.Air freight and mailing in the USAby Publications Expediting Services Inc.,200Meacham Ave.,Elmont,NY 11003.Periodical postage paid at Jamaica,NY Postmaster:Send address changes to:“Advanced Materials”c/o Wiley-VCH,111River Street,Hoboken,NJ 07030.Adv.Mater.2005,17,2523–2529www.advmat.de©2005WILEY-VCH Verlag GmbH &Co.KGaA,Weinheim2523Upcoming ArticlesG.L.Liu,Y.Lu,J.Kim,J.C.Doll,L.P .Lee*Magnetic Nanocrescents as Controllable Surface-Enhanced Raman Scattering Nanoprobes for Biomolecular ImagingPublished Online:September 29,2005DOI:10.1002/adma.200501064X.Liu,J.Ly,S.Han,D.Zhang,A.Requicha,M.E.Thompson,C.Zhou*Synthesis and Electronic Properties of Individual Single-Walled Carbon Nanotube/Polypyrrole Composite NanocablesPublished Online:September 29,2005DOI:10.1002/adma.200501211S.W.Lee,R.G.Sanedrin,B.-K.Oh,C.A.Mirkin*Nanostructured Polyelectrolyte Mul-tilayer Organic Thin Films Generated via Parallel Dip-Pen Nanolithography Published Online:September 29,2005DOI:10.1002/adma.200501120N.Tétreault,G.von Freymann,M.Deubel,M.Hermatschweiler,F.Pérez-Willard,S.John,M.Wegener,G.A.Ozin*New Route to Three-Dimensional Photonic Bandgap Materials:Silicon Double Inversion of Polymer TemplatesPublished Online:September 26,2005DOI:10.1002/adma.200501674All our articles are available online in advance of print.The articles listed here have been judged by the referees or the editor to be either very important or very urgent and were immediately copyedited,proofread,and published online when the manuscript arrived in the editorial office in its final form.As long as there is no page number available,online manuscripts should be cited in the following manner:Authors,Adv.Mater.,online publication date,DOI.REVIEWNanocrystalsD.Kovalev,*M.Fujii ........2531–2544Silicon Nanocrystals:Photosensitizers for OxygenMoleculesThe features of nanoscale silicon that make it different from the bulk result in very efficient energy transfer from excitons confined in silicon nanocrystals to oxygen molecules following their activation to the highly reactive singlet state (see Figure).The mechanism for the photosensitization of oxygen molecules using silicon nanocrystals is reviewed.We discuss,in addition,the implications of these findings for physics,chemistry,biology,and medicine.COMMUNICATIONSMagnetic MaterialsC.Enkrich,F.Pérez-Willard,D.Gerthsen,J.F.Zhou,T.Koschny,C.M.Soukoulis,M.Wegener,S.Linden*...2547–2549Focused-Ion-Beam Nanofabrication of Near-Infrared MagneticMetamaterialsSplit-ring resonators with a magnetic resonance in the near-infrared have been fabricated using the rapid-prototyping capabilities of focused-ion-beam writing.By varying the design parameters,a continuous transition from a degenerate Mie resonance to a magnetic-dipole response is shown (see Figure).In particular,a negative magnetic permeability at a wavelength of 2.4 m and a negative magneticsusceptibility at a wavelength of 1.7 m are demonstrated.Organic SemiconductorsA.Brillante,*I.Bilotti,R.G.Della Valle,E.Venuti,M.Masino,A.Girlando...2549–2553 Characterization of Phase Purity in Organic Semiconductors by Lattice-Phonon Confocal Raman Mapping: Application toPentacene Lattice-phonon confocal Raman mapping is a powerful technique to probe the crystal structure of poly-morphs of organic semiconductors.This technique is fast,reliable,and capable of monitoring physical modifications and phase inhomogeneities in crystal do-mains at the micrometer scale.Applying the technique to pentacene crystals (see Figure)shows that phase inhomo-geneities are not confined to the crystal surface,but penetrate into the crystal.Nanoparticle AssemblyS.Lin,M.Li,E.Dujardin,*C.Girard,S.Mann*..........2553–2559 One-Dimensional Plasmon Coupling by Facile Self-Assembly of Gold Nanoparticles into Branched ChainNetworks Short chains and complex networks of interconnected Au nanoparticle chains (see Figure)are produced by a simple template-free approach.Optical spectroscopy and computer simulations show that surface plasmons from individual non-contacting nanoparticles are strongly coupled in the resulting1D superstructures.These chains may pro-vide a unique way to fabricate complex subwavelength optical waveguides.NanopatterningJ.H.Moon,S.G.Jang,J.-M.Lim,S.-M.Yang*.......................2559–2562 Multiscale Nanopatterns Templated from Two-Dimensional Assembliesof PhotoresistParticles Multiscale nanopatterns fabricated by colloidal lithography,using two-dimen-sional self-assemblies of photoresist particles as masks,are presented.The colloidal masks with features of multiple length scales are obtained by photolithography and used for con-structing submicrometer-hole arrays over large areas(see Figure).By depositing functional materials through these masks,nanopatterned substrates useful in a wide range of applications can be produced.NanostructuresC.Lu,L.Qi,*J.Yang,X.Wang,D.Zhang,J.Xie,J.Ma.....2562–2567 One-Pot Synthesis of Octahedral Cu2O Nanocages via a Catalytic SolutionRoute Unique single-crystalline octahedralCu2O nanocages(see Figure)are synthesized in solution by the catalytic reduction of copper tartrate complex into octahedral Cu2O nanocrystals and a subsequent spontaneous hollowing process.A wealth of colorful nanostruc-tures with widely tunable bandgaps in the range2.6–2.2eV are obtained.The obtained nanocages may find potential use in solar-energy conversion,catalysis, and as model systems for fundamental research.2524©2005WILEY-VCH Verlag GmbH&Co.KGaA,Weinheim www.advmat.de Adv.Mater.2005,17,2523–2529Adv.Mater.2005,17,2523–2529www.advmat.de©2005WILEY-VCH Verlag GmbH &Co.KGaA,Weinheim2525PhotolithographyC.Sánchez,B.-J.de Gans,D.Kozodaev,A.Alexeev,M.J.Escuti,C.van Heesch,T.Bel,U.S.Schubert,C.W.M.Bastiaansen,*D.J.Broer ..........................2567–2571Photoembossing of Periodic Relief Structures Using Polymerization-Induced Diffusion:A CombinatorialStudyPhotoembossing is a solvent-free photo-lithographic technique for the produc-tion of polymeric relief microstructures (see Figure).A combinatorial method-ology to explore the influence of differ-ent parameters (e.g.,processing temper-ature,binder content,photoinitiator content)on the resultant relief structure is presented using an acrylate-based model system.Results are discussed in the framework of a diffusion-polymer-ization model.BiomineralizationM.Umetsu,M.Mizuta,K.Tsumoto,S.Ohara,S.Takami,H.Watanabe,I.Kumagai,T.Adschiri*..2571–2575Bioassisted Room-TemperatureImmobilization and Mineralization of Zinc Oxide—The Structural Ordering of ZnO Nanoparticles into a Flower-TypeMorphologyA peptide with an affinity for ZnO,selected by a phage-display system,pref-erentially immobilizes ZnO particles on a gold-coated polypropylene plate and assists in the homogeneous assembly of 10nm diameter ZnO nanoparticles into unique flower-like morphologies(see Figure).The peptide is selective in binding ZnO,but not ZnS or Eu 2O 3.This combinatorial library approach may yield new peptides used to create new structures via biomineralization.MicropatterningJ.Park,L.D.Fouché,P .T.Hammond*...............2575–2579Multicomponent Patterning of Layer-by-Layer Assembled Polyelectrolyte/Nanoparticle Composite Thin Films with ControlledAlignmentComposite thin films of polyelectrolytes and fluorescent nanoparticles can be directly transfer-printed onto various substrates including indium tin oxide coated poly(ethylene terephthalate).The sequential transfer printing of thin films with controlled alignment intro-duces multicomponent patterns onto substrates,demonstrating possible practical device fabrication using functional polyelectrolyte multilayer composite thin films (see Figure).Liquid CrystalsZ.An,J.Yu,S.C.Jones,S.Barlow,S.Yoo,B.Domercq,P .Prins,L.D.A.Siebbeles,B.Kippelen,S.R.Marder*....................2580–2583High Electron Mobility in Room-Temperature DiscoticLiquid-Crystalline Perylene DiimidesPerylene diimide discotic columnar liquid-crystalline mesophases (see Figure)can show very high electron mobilities under ambient conditions.While the mobilities are strongly dependent on sample morphology and processing conditions,mobilities as high as 1.3cm 2V –1s –1are measured,greater than that of amorphoussilicon.Self-Assembled MonolayersW.Eck,*A.Küller,M.Grunze,B.Völkel,A.Gölzhäuser..2583–2587 Freestanding Nanosheets from Crosslinked Biphenyl Self-AssembledMonolayers Freestanding nanosheets(see Figure) with the thickness of a single molecule and lateral dimensions in the microme-ter range have been obtained by the release of self-assembled monolayers from the underlying surface by dissolu-tion of the substrate or by scissionof the anchor group–substrate bonds. The self-assembled monolayers are composed of biphenyl units that are crosslinked by electron irradiation.Self-AssemblyH.Fan,*E.Leve,J.Gabaldon,A.Wright,R.E.Haddad,C.J.Brinker......................2587–2590 Ordered Two-and Three-Dimensional Arrays Self-Assembled fromWater-SolubleNanocrystal–Micelles Two-and three-dimensional,ordered nanocrystal arrays are formed fromthe self-assembly of water-soluble nanocrystal–micelles that are prepared using surfactant encapsulation tech-niques.This new method is simple, widely applicable,and can be usedto prepare water-soluble nanocrystals with different compositions and shapes, such as sphere,rod,and cube,as wellas their ordered arrays(see Figure).Ap-plications in fabrication of SERS-based sensor platforms are envisaged.Mesostructured MaterialsR.C.Hayward,B.F.Chmelka,E.J.Kramer*....................2591–2595 Crosslinked Poly(styrene)-block-Poly(2-vinylpyridine)Thin Filmsas Swellable Templates for Mesostructured Silica andTitania Mesostructured inorganic filmsare formed from pre-organizedblock-copolymer thin films.The diblock copolymer used,poly(d8-styrene)-block-poly(2-vinylpyridine),was first crosslinked,thus retaining its morphol-ogy.Silica and titania were incorporated into the structure and the polymer was subsequently removed,generating mesoporous inorganic films whose morphologies were directly related to those of the block-copolymer template films(see Figure).Y.Kubo,N.Yamada.........2596–2599 Synergistic Effect of Inorganic and Organic Components on SolidAcid/Base Properties of Organosilox-ane-Based Inorganic–Organic Hybrid Materials-C8H-C3H-C2H-CHSiOMOLiCaYAlTiNbSi-RInorganic componentsOrganicgroupsofsiloxane(-RSiorganic groups bonded to silicon inorganosiloxane networks are found tosynergistically affect the solid acid/baseproperties arising from inorganic com-ponents(see Figure).This synergisticeffect may result in innovative materialswith applications in fast proton conduc-tors,selective catalysts,efficientmembranes,high-sensitivity sensors,and selective absorbents.2526©2005WILEY-VCH Verlag GmbH&Co.KGaA,Weinheim www.advmat.de Adv.Mater.2005,17,2523–2529Adv.Mater.2005,17,2523–2529www.advmat.de©2005WILEY-VCH Verlag GmbH &Co.KGaA,Weinheim2527Surface-Nucleated Assemblyof Fibrillar Extracellular Matricescollagen (COL),as shown in the Figure,and exhibit increased cell-proliferation rates.Organic TransistorsM.Shkunov,*R.Simms,M.Heeney,S.Tierney,I.McCulloch ...2608–2612Ambipolar Field-Effect Transistors Based on Solution-Processable Blends of Thieno[2,3-b ]thiophene Terthiophene Polymer and MethanofullerenesThin-film field-effect transistors showing n-and p-type conduction under different bias conditions are produced from solution-processable ambipolar blends ofthieno[2,3-b ]thiophene terthiophene polymer and phenyl C 61butyric acid methyl ester (see Figure).Balanced charge transport in this blend is achieved by treating the insulator interface with alkyl-chain plementary-like inverters have been fabricated ona single substrate,showing a maximum gain of 65.SSSSRR **nOOCH Tissue EngineeringH.-W.Jun,V .Yuwono,S.E.Paramonov,J.D.Hartgerink*...............2612–2617Enzyme-Mediated Degradation of Peptide-Amphiphile Nanofiber NetworksPeptide-amphiphile nanofibers are prepared that incorporate a peptide sequence permitting enzyme-mediated degradation (see Figure).Cleavage of the peptide sequence results in breakdown of the nanostructure and,consequently,the mechanical proper-ties.This novel elasticnanofibernetwork is able to encapsulate dental pulp cells,supporting their proliferation and migration,and mimics several key properties of natural extracellular matrix.Materials TestingC.A.Tweedie,D.G.Anderson,nger,K.J.Van Vliet*.................2599–2604Combinatorial Material Mechanics:High-Throughput Polymer Synthesis and Nanomechanical ScreeningCombinatorial materials sciencerequires parallel advances in materials characterization.A high-throughput nanoscale synthesis/nanomechanical profiling approach capable of accurately screening the mechanical properties of 1,700photopolymerizable materials (see Figure,scale bar:100 m)within a large,discrete polymer library ispresented.This approach enables rapid correlation of polymer composition,processing,and structure with mechanical performance metrics.2528©2005WILEY-VCH Verlag GmbH &Co.KGaA,Weinheimwww.advmat.deAdv.Mater.2005,17,2523–2529Substratetheir concentration is increased.Nanoporous MaterialsG.-D.Fu,Z.Shang,L.Hong,E.-T.Kang,*K.-G.Neoh ..2622–2626Nanoporous,Ultralow-Dielectric-Constant Fluoropolymer Films from Agglomerated and Crosslinked Hollow Nanospheres of Poly(pentafluorostyr-ene)-block -Poly(divinylbenzene)Nanoporous fluoropolymer films with dielectric constants below 2are prepared via consecutive surface-initiated atom transfer radical polymerizations of pentafluo-rostyrene (PFS)and divinylbenzene (DVB)on silica nanospheres.After agglomera-tion of the nanospheres,crosslinking of the nanospheres by UV ,and removal of the silica cores (see Figure),a nanoporous fluoropolymer film with a dielectric constant as low as 1.7is formed.Metal NanowiresX.M.Sun,Y.D.Li*.........2626–2630Cylindrical Silver Nanowires:Preparation,Structure,and Optical PropertiesCylindrical and pentagonal Ag nano-wires (see Figure)are selectivelyprepared in amorphous carbonaceous sheaths via a controlled hydrothermal reaction.Results indicate that theamorphous coating layer is responsible for the cross-section symmetry selected synthesis.The distinctive optical proper-ties measured fit well with the theoreti-cal predictions,and applications in electronic nanodevices are envisaged.Polymer ElectrolytesA.J.Bhattacharyya,*J.Fleig,Y.-G.Guo,J.Maier ...........2630–2634Local Conductivity Effects in Polymer ElectrolytesRoom-temperature area mapping of polymer electrolyte films at thenanoscale reveals considerable hetero-geneity,with the positional ionicconductivity varying up to four orders of magnitude.Measurements indicate the presence of a bimodal conductivity distribution (see Figure),with highly conducting regions being amorphous but non-percolating at room tempera-ture.Adv.Mater.2005,17,2523–2529www.advmat.de©2005WILEY-VCH Verlag GmbH &Co.KGaA,Weinheim2529NanostructuresC.Ma,Z.L.Wang*..........2635–2639Road Map for the Controlled Synthesis of CdSe Nanowires,Nanobelts,and Nanosaws—AStep Towards NanomanufacturingThe first systematic study on the growth of one-dimensional CdSe nanostructures (see Figure)using a vapor–liquid–solid process by varying a wide range of experimental conditions is reported.The results yield a road map for the controlled growth of CdSe nanowires,nanobelts,and nanosaws,and it gives guidance for scaling up the synthesis of CdSe nanostructures.CONFERENCE CALENDAR.............................................2640–2642INDEX.............................................2643–2644。
Fortinet FortiSandbox 产品说明书
The ultimate combination of proactive mitigation, advanced threat visibility and comprehensive reporting.§Secure virtual runtime environment exposes unknown threats §Unique multi-layer pre-filters for fast and effective threat detection §Rich reporting for full threat lifecycle visibility§Inspection of many protocols in one appliance simplifies deployment and reduces cost§Integration with FortiGate enhances rather than duplicates security infrastructure§Validated security with NSS BDS (Breach Detection Systems) testingengine, queries to cloud-based threat databases and OS-independent simulation with a code emulator, followed by execution in the full virtual runtime environment. Once a malicious code is detected, results are submitted for antimalware signature creation as well as updates to other threat databases.Actionable InsightAll classifications — malicious and high/medium/low risk — are presented within an intuitive dashboard. Full threat information from the virtual execution — including system activity, exploit efforts, web traffic, subsequent downloads, communication attempts and more — is available in rich logs and reports.DATA SHEETFortiSandbox ™Multi-layer proactive threat mitigationDATA SHEET: FortiSandbox ™DEPLOYMENT OPTIONSStandaloneThis deployment mode relies on inputs from spanned switch ports and/or administrators’ on-demand file uploads using the GUI. It is the most suitable infrastructure for adding protection capabilities to existing threat protection systems from various vendors.*FortiGate/FortiMail IntegratedThe FortiGate, as the Internet security gateway, can be set up to submit suspicious files to the FortiSandbox. This seamless integration reduces network complexity and expands the applications and protocols supported including SSL encrypted ones such as HTTPS.* Requires: FortiOS V5.0.4+, FortiMail V5.1+Distributed FortiGate IntegratedThis deployment is attractive for organizations that have distributed environments, where FortiGates are deployed in the branch offices and submit suspicious files to a centrally-located FortiSandbox. This setup yields the benefits of lowest TCO and protects against threats in remote locations.Easy DeploymentFortiSandbox supports inspection of many protocols in one unified solution, thus simplifies network infrastructure and operations. Further, it integrates with FortiGate as a new capability within your existing security framework.The FortiSandbox is the most flexible threat analysis appliance in the market as it offers various deployment options for customers’ unique configurations and requirements. Organizations can also have all three input options at the same time.Dashboard widgets — real-time threat statusand callback detection.File Analysis ToolsReports with captured packets, original file, tracer log andscreenshot provide rich threat intelligence and actionable insightafter files are examined. This is to speed up remediation andupdated protection.AV engine§Applies top-rated (95%+ Reactive and Proactive) AV Scanning. Serves as anefficient pre-filter.Cloud Query§Real-time check of latest malware information §Access to shared information for instant malware detectionCode emulation§Quickly simulates intended activity§OS independent and immune toevasion/obfuscation Full Virtual sandbox§Secure run-time environment for behavioral analysis/rating§Exposes full threat lifecycle informationCall Back Detection§Identifies the ultimate aim, call back and exfiltrationMulti-tiered file processing optimizes resource usage that improves security, capacity and performanceDATA SHEET: FortiSandbox ™FEATURESFortiMail submits and queues for suspicious contentInternetS an db ox i n sp e c t i o nI n s pe c t e d e m ai l sClean emails delivered to protected mail servers.F ee d ba c k t oF o r t i M a i lCPRL analysis and real-time sandbox malware analysis performed at FortiMail oninbound and outbound emails.F e ed b a ck t o F o r t i G u a r dFortiSandbox executes,analyzes and feeds back to FortiMail and FortiGuard.Email traf cRemediation with FortiMailWith many advanced threats starting with a targeted email that contains custom malware, in addition to social engineering that entices the user to open it, organizations are extending their secure email gateway (SEG) with integrated sandboxing. Specifically, the SEG will hold messages while additional analysis is performed in this contained run-time environment and, ultimately, apply policies based on its returned findings.Administration§Supports WebUI and CLI configurations §Multiple administrator account creation §Configuration file backup and restore§Notification email when malicious file is detected§Weekly report to global email list and FortiGate administrators§Centralized search page which allows administrators to build customized search conditions §Frequent signature auto-updates§Automatic check and download new VM images §VM status monitoring Networking/Deployment§Static Routing Support§File Input: Offline/sniffer mode, On-demand file upload, file submission from integrated device(s)§Web-based API with which users can upload samples to scan indirectly§Option to create simulated network for scanned file to access in a closed network environment §Device Integration:– File Submission input: FortiGate, FortiMail – Update Database host: FortiManager– Remote Logging: FortiAnalyzer, Syslog ServerAdvanced Threat Protection§Virtual OS Sandbox:– Concurrent Windows instances– Anti-evasion techniques: sleep calls, process and registry queries– C allback Detection: malicious URL visit, Botnet C&Ccommunication and Attacker traffic from activated malware – D ownload Capture packets, Original File, Tracer logand Screenshot§Unlimited file size support, maximum file size configurable §File type support: – A rchived: .tar, .gz, .tar.gz, .tgz, .zip, .bz2, .tar.bz2, .bz, .tar.Z,.cab, .rar, .arj – E xecutable files: (eg: .exe, .dll), PDF , Windows OfficeDocument, Javascript, AdobeFlash and JavaArchive (JAR) files – Media files: .avi, .mpeg, .mp3, .mp4Protocols/applications supported:– Sniffer mode: HTTP , FTP , POP3, IMAP , SMTP , SMB – I ntegrated mode with FortiGate: HTTP , SMTP , POP3, IMAP ,MAPI, FTP , IM and their equivalent SSL encrypted versions – Integrated mode with FortiMail: SMTP , POP3, IMAP §Network Threat Detection in Sniffer Mode: Identify Botnet activties and network attacks, malicious URL visit§Scan SMB/NSF network share and quarantine suspicious files. Scan can be scheduled§Scan websites with URL links§Option to auto-submit suspicious files to cloud service for manual analysis and signature creation§Option to forward files to a network share for further third-party scanningMonitoring and Report§Real-Time Monitoring Widgets (viewable by source and time period options): Scanning Result statistics, Scanning Activities (over time), Top Targeted Hosts, Top Malware, Top Infectious URLs, Top Callback Domains§Drilldown Event Viewer: Dynamic table with content of actions, malware name, rating, type, source, destination, detection time and download path§Logging — GUI, download RAW log file§Report generation for malicious files: Detailed reports on file characteristics and behaviors – File Modification, ProcessBehaviors, Registry Behaviors, Network Behaviors, VM snapshot §Further Analysis: Downloadable files — Sample file, Sandbox tracer logs and PCAP captureFEATURES SUMMARYDATA SHEET: FortiSandbox ™AV Scanning (Files/Hour)Hardware DependentNumber of VMs2 to 52 (Upgrade via appropriate licenses)Height x Width x Length (mm)89 x 437 x 36884 x 482 x 755Weight27.60 lbs (12.52 kg)71.5 lbs (32.5 kg)SPECIFICATIONSUL/cUL, CB, GOST 1 GE SFP LX transceiver moduleFG-TRAN-LX 1 GE SFP LX transceiver module for all systems with SFP and SFP/SFP+ slots.10 GE SFP+ transceiver module, short range FG-TRAN-SFP+SR 10 GE SFP+ transceiver module, short range for all systems with SFP+ and SFP/SFP+ slots.10 GE SFP+ transceiver module, long rangeFG-TRAN-SFP+LR10 GE SFP+ transceiver module, long range for all systems with SFP+ and SFP/SFP+ slots.ORDER INFORMATIONGLOBAL HEADQUARTERS Fortinet Inc.899 Kifer Road Sunnyvale, CA 94086 United StatesTel: +1.408.235.7700 /sales EMEA SALES OFFICE120 rue Albert Caquot06560, Sophia Antipolis,FranceTel: +33.4.8987.0510APAC SALES OFFICE300 Beach Road 20-01The ConcourseSingapore 199555Tel: +65.6513.3730LATIN AMERICA SALES OFFICEProl. Paseo de la Reforma 115 Int. 702Col. Lomas de Santa Fe,C.P. 01219Del. Alvaro ObregónMéxico D.F.Tel: 011-52-(55) 5524-8480Copyright© 2015 Fortinet, Inc. All rights reserved. Fortinet®, FortiGate®, FortiCare® and FortiGuard®, and certain other marks are registered trademarks of Fortinet, Inc., in the U.S. and other jurisdictions, and other Fortinet names herein may also be registered and/or common law trademarks of Fortinet. All other product or company names may be trademarks of their respective owners. Performance and other metrics contained herein were attained in internal lab tests under ideal conditions, and actual performance and other results may vary. Network variables, different network environments and other conditions may affect performance results. Nothing herein represents any binding commitment by Fortinet, and Fortinet disclaims all warranties, whether express or implied, except to the extent Fortinet enters a binding written contract, signed by Fortinet’s General Counsel, with a purchaser that expressly warrants that the identified product will perform according to certain expressly-identified performance metrics and, in such event, only the specific performance metrics expressly identified in such binding written contract shall be binding on Fortinet. For absolute clarity, any such warranty will be limited to performance in the same ideal conditions as in Fortinet’s internal lab tests. In no event does Fortinet make any commitment related to future deliverables, features or development, and circumstances may change such that any forward-looking statements herein are not accurate. Fortinet disclaims in full any covenants, representations, and guarantees pursuant hereto, whether express or implied. Fortinet reserves the right to change, modify, transfer, or otherwise revise this publication without notice, and the most current version of the publication shall be applicable.DATA SHEET: FortiSandbox™。
碧云天生物技术 Plerixafor (CXCR拮抗剂) 产品说明书
碧云天生物技术/Beyotime Biotechnology订货热线：400-168-3301或800-8283301订货e-mail：******************技术咨询：*****************网址：碧云天网站微信公众号Plerixafor (CXCR拮抗剂)产品编号产品名称包装SD2380-10mM Plerixafor (CXCR拮抗剂) 10mM×0.2mlSD2380-5mg Plerixafor (CXCR拮抗剂) 5mgSD2380-25mg Plerixafor (CXCR拮抗剂) 25mg产品简介：化学信息：化学名1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane简称Plerixafor别名AMD3100, AMD 3100, AMD 3329, AMD-3100, AMD-3329, Bicyclam, JM 3100, JM-3100, JM3100, Mezobil, Mozobil, Plerixafor hydrochloride, RPA bicyclam中文名普乐沙福化学式C28H54N8分子量502.78 CAS号110078-46-1 纯度98%溶剂/溶解度Water 3mg/ml warming; DMSO <1mg/ml; Ethanol 100mg/ml溶液配制5mg加入0.99ml DMSO，或每5.03mg加入1ml DMSO，配制成10mM溶液。
SD2380-10mM用DMSO配制。
生物信息：产品描述Plerixafor (AMD3100)是一种趋化因子受体拮抗剂，作用于CXCR4和CXCL12介导的趋化性，无细胞试验中IC50分别为44nM和5.7nM。
信号通路GPCR & G Protein靶点CXCL12-mediatedchemotaxisCXCR4 －－－IC50 5.7nM 44nM －－－体外研究Plerixafor抑制CXCL12介导的趋药性，效能稍微高于其对CXCR4的亲和力。
F-STOP 对照图片，病毒免疫咖啡草坛说明书
F -S T O P ™ F o r P i c t u r e -P e r f e c t , D i s e a s e -F r e e T u r f g r a s s 12770• Provides Systemic Prevention And Control Of Turfgrass Diseases• Prevents Over 15 Major Lawn Diseases • For Use On All Types Of Home Lawns • One Application Protects For Up To 4 WeeksKEEP OUT OF REACH OF CHILDRENCAUTIONBUYER ASSUMES ALL RISKS OF USE, STORAGE OR HANDLING OF THIS MATERIALNOT IN STRICT ACCORDANCE WITH DIRECTIONS GIVEN HEREWITH.NET WEIGHT 10 LBS. (4.53 KG)ACTIVE INGREDIENT:myclobutanil: a-butyl-a-(4-chlorophenyl)-1-H-1,2,4 triazole-propanenitrile: ...............0.39%OTHER INGREDIENTS: .............................................................................................99.61%TOTAL .....................................................................................................................100.00%This product contains 0.195 lb.. of myclobutanil per 50 lb. bag.C o v e r s U p T o 2,500 S q . F t .F-STOP ™ For Picture-Perfect, Disease-Free TurfgrassF -S T O P ™F o r P i c t u r e -P e r f e c t , D i s e a s e -F r e e T u r f g r a s sF-STOP ™For Picture-Perfect, Disease-Free TurfgrassPRECAUTIONARY STATEMENTSHAZARDS TO HUMANS AND DOMESTIC ANIMALSCauses Moderate Eye Irritation.Avoid contact with eyes or clothing. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco, or using the toilet.Notice: Read the entire label. Use only according to label directions. Before using this product, read “Warranty Disclaimer,” “Inherent Risks of Use,” and “Limitation of Remedies” at end of Directions for Use. If terms are unacceptable, return at once unopened.In case of emergency endangering health or the environment involving this product,call 1-800-992-5994Agricultural Chemical: Do not ship or store with food, feeds, drugs, or clothing.FIRST AIDIf in eyes: Hold eye open and rinse slowly and gently with water for 15-20 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. Call a Poison Control Center or doctor for treatment advice. Have the product container or label with you when calling a Poison Control Center or doctor, or going for treatment. You may also contact 1-800-992-5994 for emergency treatment information.ENVIRONMENTAL HAZARDSThis pesticide is toxic to fish. To protect the environment, do not allow pesticide to enter or run off into storm drains, drainage ditches, gutters or surface waters. Applying this product in calm weather when rain is not predicted for the next 24 hours will help ensure that wind or rain does not blow or wash pesticide off the treatment area. Sweeping any product that lands on a driveway, sidewalk, or street, back onto the treated area of the lawn or garden will help to prevent runoff to water bodies or drainage systems.DIRECTIONS FOR USEIt is a violation of Federal law to use this product in a manner inconsistent with its labeling. Read all directions carefully before applying this product.Not for use on turfgrass being grown for sale or other commercial use as sod, or for commercial seed productions, or for research purposes.STORAGE AND DISPOSALDo not contaminate water, food or feed by storage and disposal.PESTICIDE STORAGE: Keep away from fire and sparks. Store in a cool, dry, well-ventilated area. CONTAINER HANDLING: Nonrefillable container. Do not reuse or refill this container.If empty: Place in trash or offer for recycling if available.If partly filled: Call your local solid waste agency for disposal instructions. Never place unused product down any indoor or outdoor drain.HOW THIS PRODUCT WORKSferti•lome® F-STOP™is a systemic, protectant and curative fungicide for the control of listed diseases in established home lawns and ornamental turfgrass. Optimum disease control is achieved when this product is applied to established turfgrass in a regularly scheduled preventative program. Use this product in conjunction with turf management practices that promote good plant health and optimum disease control. The key to selecting a fungicide is the proper diagnosis of the organism causing the disease. Diagnostic kits, extension experts, or other identification methods should be used when developing disease control strategies.HOW TO APPLYApply ferti•lome® F-STOP™ uniformly over the turfgrass area using a properly calibrated drop or rotary-type spreader designed to apply granules. Before each application, calibrate the spreader according to the equipment manufacturer’s directions. Check frequently to make sure equipment is operating properly and distributing product uniformly. A more uniform application may be achieved by spreading half of the required amount of product over the area and then applying the remaining half in swaths at a right angle to the first. Avoid skips and excessive overlaps during application. Avoid the use of spreaders that apply this product in narrow rows or concentrated bands.Wash hands with soap and water promptly after use.Do not allow people or pets to contact treated area until after product dust has settled into the turfgrass, or if watered in, after the turfgrass surface in the treated area has dried.WHEN TO APPLYReduce the interval between applications of this product when conditions are favorable for disease development. Unless otherwise specified, when disease pressure is high or when used as a curative, use higher rates of ferti•lome® F-STOP™ and shorter application interval. Under light to moderate disease pressure apply this product at the low use rate and/or longer application intervals. To avoid pick-up, lightly irrigate treated areas soon after application. On short cut bentgrass (1/2 inch or less) when temperatures are above 80°F, apply only to dry foliage.HOW MUCH TO APPLYOptimum disease control is achieved when ferti•lome® F-STOP™ is applied in a preventative disease control program at a rate of 4 lb per 1,000 sq. ft. See the following table for specific application rates for various diseases. Under any circumstances, do not apply more than 46 lb of this product per1,000 sq. ft. per year.SPREADER GUIDEONE BAG WILL COVER UP TO 2,500 SQUARE FEETSPREADER SPREADER SETTINGS Scotts®/Republic Accugreen (Drop) 4 1/4Scotts®/Republic Speedy Green (Broadcast) 3 3/4 ferti•lome® /EarthWay Ev-N-Spred (Broadcast)14TERMS AND CONDITION OF USEIf terms of the following Warranty Disclaimer, Inherent Risks of Use, and Limitation of Remedies are not acceptable, return unopened package at once to the Seller for a full refund of purchase price paid. Otherwise, use by the Buyer or any other user constitutes acceptance of the terms under Warranty Disclaimer, Inherent Risks of Use, and Limitations of Remedies.WARRANTY DISCLAIMERSeller warrants that this product conforms to the chemical description of the label and is reasonably fit for the purposes stated on the label when used in strict accordance with the directions, subjectto the Inherent Risks set forth below. Seller MAKES NO OTHER EXPRESS OR IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE OR ANY OTHER EXPRESS OR IMPLIED WARRANTY.INHERENT RISKS OF USEIt is impossible to eliminate all risks associated with use of this product. Plant injury, lack of performance, or other unintended consequences may result because of such factors as use of the product contrary to label instructions (including conditions noted on the label, such as unfavorable temperature, soil conditions, etc.), abnormal conditions (such as excessive rainfall, drought, tornadoes, hurricanes), presence of other materials, the manner of application, or other factors, allof which are beyond the control of the Seller. To the extent allowed by law, all such risks shall be assumed by the Buyer.LIMITATION OF REMEDIESTo the extent consistent with applicable law, the exclusive remedy for losses or damages resulting from this product (including claims based on contract, negligence, strict liability, or other legal theories), shall be limited to, at Seller’s election, one of the following:1. Refund of purchase price paid by Buyer or user for product bought, or2. Replacement of amount of product used.To the extent allowed by law, Seller shall not be liable for the losses of damages resulting from the handling or use of this product unless Seller is promptly notified of such loss or damage in writing. In no case shall Seller be liable for consequential or incidental damages or losses.The terms of the Warranty Disclaimer and Inherent Risks of Use above and this Limitation of Remedies cannot be varied by any written or verbal statements or agreements. No employee or sales agent of Seller or the Seller is authorized to vary or exceed the terms of the Warranty Disclaimer or this Limitation of Remedies in any manner.Disease ferti•lome® F-STOP™(lb/1,000 sq ft)ApplicationInterval/Timing(Days)Directions RestrictionsAnthracnose Red Thread Septoria Leaf Spot 414 - 21Apply when conditions are favorable for disease development.Do not apply more than 46pounds of product per 1,000sq. ft. per year.For Nassau and Suffolkcounties in New York State,do not apply more than 11.5lb of this product per 1,000sq ft per year.Brown Patch14Begin applications when conditions are favorable for disease development andb efore disease symptoms are apparentCopper SpotZonate Leaf SpotApply when conditions are favorable for disease development.Crown Rot Leaf Spot Melting-Out Apply when conditions are favorable for disease development. For crown rot, water in with 3 to 4 gallons of water per 1,000 sq. ft. to increase penetration to crown a nd roots.Dollar Spot14 - 28Apply when conditions are favorable for disease development. Make no morethan 3 consecutive applications for Dollar Spot control before rotating to aregistered fungicide with a diiferent mode of actionFusarium Blight14 - 21Apply when conditions are favorable for disease development.Fusarium Patch(Pink Snow Mold)21 - 28Apply when conditions are favorable for disease development.Gray Leafspot14Apply prior to snow cover.Leaf Spot Apply in the fall after turfgrass enters dormancy and/or in the spring prior to theinitiation of growth.Necrotic Ring Spot Spring: 28Make applications on a preventative basis in early to mid-spring.Necrotic Ring Spot Fall: 28Make 2 applications beginning in August before the turfgrass goes dormant.Powdery MildewRusts14 - 28Apply when conditions are favorable for disease development.Summer Patch Begin applications in the spring when conditions are favorable for disease de-velopment. Make 2 to 4 applications depending on recommendations from localTurfgrass Extension Experts.Water in with at least 3 to 4 gallons of water per 1,000 sq. ft. to increase penetra-tion to crown and roots.Manufactured by:230 FM 87 • BONHAM, TEXAS 75418EPA Reg. No. 62719-461-7401 EPA Est. No. 7401-TX-01Visit Us At: Product Questions? 855-270-477612770-0515-TP。
Pyxis Lab ST-588 PTSA Fluorescent Polymer Dual Inl
ST-588PTSA/Fluorescent Polymer DualInline SensorUser ManualOctober12,2020Rev.2.00Pyxis Lab,Inc.1729Majestic Dr.Suite5Lafayette,CO80026USA©2017Pyxis Lab,Inc.Pyxis Lab Proprietary and ConfidentialTable of Contents1Introduction21.1Main Features (2)2Specifications3 3Unpacking Instrument43.1Standard Accessories (4)3.2Optional Accessories (5)4Installation64.1ST-588Piping (6)4.2ST-588SS Piping (6)4.3Wiring (7)4.4Connecting via Bluetooth (8)4.5Connecting via USB (8)5Setup and Calibration with uPyxis®Mobile App95.1Download uPyxis®Mobile App (9)5.2Connecting to uPyxis®Mobile App (9)5.3Calibration Screen and Reading (10)5.4Diagnosis Screen (11)5.5Device Info Screen (12)6Setup and Calibration with uPyxis®Desktop App126.1Install uPyxis®Desktop App (12)6.2Connecting to uPyxis®Desktop App (13)6.3Information Screen (13)6.4Calibration Screen (14)6.5Diagnosis Screen (14)7Outputs157.14–20mA Output Setup (15)7.2Communication using Modbus RTU (15)8Sensor Maintenance and Precaution158.1Methods to Cleaning the ST-588 (16)8.2Storage (16)9Troubleshooting17 10Contact Us18Warranty InformationConfidentialityThe information contained in this manual may be confidential and proprietary and is the property of Pyxis Lab,rmation disclosed herein shall not be used to manufacture,construct,or otherwise reproduce the goods rmation disclosed herein shall not be disclosed to others or made public in any manner without the express written consent of Pyxis Lab,Inc.Standard Limited WarrantyPyxis Lab warrants its products for defects in materials and workmanship.Pyxis Lab will,at its option,repair or replace instrument components that prove to be defective with new or remanufactured components (i.e.,equivalent to new).The warranty set forth is exclusive and no other warranty,whether written or oral, is expressed or implied.Warranty TermThe Pyxis warranty term is thirteen(13)months ex-works.In no event shall the standard limited warranty coverage extend beyond thirteen(13)months from original shipment date.Warranty ServiceDamaged or dysfunctional instruments may be returned to Pyxis for repair or replacement.In some in-stances,replacement instruments may be available for short duration loan or lease.Pyxis warrants that any labor services provided shall conform to the reasonable standards of technical com-petency and performance effective at the time of delivery.All service interventions are to be reviewed and authorized as correct and complete at the completion of the service by a customer representative,or des-ignate.Pyxis warrants these services for30days after the authorization and will correct any qualifying deficiency in labor provided that the labor service deficiency is exactly related to the originating event.No other remedy,other than the provision of labor services,may be applicable.Repair components(parts and materials),but not consumables,provided during a repair,or purchased individually,are warranted for90days ex-works for materials and workmanship.In no event will the in-corporation of a warranted repair component into an instrument extend the whole instrument’s warranty beyond its original term.Warranty ShippingA Repair Authorization(RA)Number must be obtained from Pyxis Technical Support before any product can be returned to the factory.Pyxis will pay freight charges to ship replacement or repaired products to the customer.The customer shall pay freight charges for returning products to Pyxis.Any product returned to the factory without an RA number will be returned to the customer.To receive an RMA you can generate a request on our website at https:///request-tech-support/.Pyxis Technical SupportContact Pyxis Technical Support at+1(866)203-8397,*********************,or by filling out a request for support at https:///request-tech-support/.1IntroductionThe Pyxis ST-588inline fluorometer probe simultaneously measures the concentration of PTSA and Fluores-cent Polymer in water.It can be simply inserted to the compression fitting port of a custom-made tee.The standard ST-001installation tee provided with each ST-588sensor,has two¾inch female NPT ports and can be placed to an existing¾inch sample water line.Pyxis Lab also offers2”and3”Tee formats for larger flow installations.The4–20mA current output of the ST-588probe can be connected to any controller that accepts an isolated or non-isolated4–20mA input.The ST-588probe is a smart device.In addition to mea-suring PTSA and Fluorescent Polymer,the ST-588probe has extra photo-electric components that monitor the color and turbidity of the sample water.This extra feature allows automatic color and turbidity com-pensation to eliminate interference commonly associated with real-world waters.The Pyxis ST-588probe has a short fluidic channel and can be easily cleaned.The fluidic and optical ar-rangement of the ST-588probe is designed to overcome shortcomings associated with other fluorometers that have a distal sensor surface or a long,narrow fluidic cell.Traditional inline fluorometers are susceptible to color and turbidity interference and fouling and are difficult to properly clean.1.1Main FeaturesThe ST-588measures PTSA and Fluorescent Polymer in a water sample and includes the following features:•Easy calibration with using uPyxis®Mobile or Desktop App.•Automatic compensation for turbidity up to150NTU and color created by up to10ppm iron or equivalent to10ppm humic acid.•Diagnostic information(probe fouling,color or turbidity over range,failure modes)are available in uPyxis®App or via Modbus RTU.•Easy to remove from the system for cleaning and calibration without the need for any tools.2SpecificationsTable1.ST-588Specifications*With Pyxis’s continuous improvement policy,these specifications are subject to change without notice.†The fluorescent polymer concentration scale is based on the polymer containing0.25mole%fluorescent monomer.Typical polymer specifications are attached below but may vary by producer.‡See Figure4for ST-588SS dimensions.3Unpacking InstrumentRemove the instrument and accessories from the shipping container and inspect each item for any damage that may have occurred during shipping.Verify that all accessory items are included.If any item is missing or damaged,please contact Pyxis Lab Customer Service at*********************.3.1Standard Accessories•Tee Assembly3/4”NPT(1x Tee,O-ring,and Nut)P/N:ST-001*NOTE*ST-001is not included for ST-588SS•8-Pin Female Adapter/Flying Leads Cable(1.5ft)•User Manual available online at https:///support/3.2Optional AccessoriesFigure1.4Installation4.1ST-588PipingThe provided ST-001Tee Assembly can be connected to a pipe system through the3/4”female ports,either socket or NPT threaded.To properly install the ST-588probe into the ST-001Tee Assembly,follow the steps below:1.Insert the provided O-ring into the O-ring groove on the tee.2.Insert the ST-588probe into the tee.3.Tighten the tee nut onto the tee to form a water-tight,compression seal.Figure2.Dimension of the ST-588and the ST-001Tee Assembly(mm)4.2ST-588SS PipingThe ST-588SS probe has3/4”female NPT threaded ports on the probe itself and therefore does not require a custom tee assembly.It is recommended that two3/4”NPT to1/4”tubing adapters are used to connect the probe to the sampling system.Sample water entering the probe must be cooled down to below104°F (40°C).The probe can be held by a1.75-inch pipe clamp or mounted to a panel with four1/4-28bolts.See Figure4for ST-588SS dimensions.Figure3.Dimension of the ST-588SS(inch)4.3WiringIf the power ground terminal and the negative4–20mA terminal in the controller are internally connected (non-isolated4–20mA input),it is unnecessary to connect the4–20mA negative wire(gray)to the4–20mA negative terminal in the controller.If a separate DC power supply other than that from the controller is used,make sure that the output from the power supply is rated for22–26VDC@85mA.*NOTE*The negative24V power terminal(power ground)and the negative4–20mA ter-minal on the ST-588probe are internally connected.Follow the wiring table below to connect the ST-588probe to a controller:Table2.*Internally connected to the power ground4.4Connecting via BluetoothA Bluetooth adapter(P/N:MA-WB)can be used to connect a ST-588probe to a smart phone with the uPyxis®Mobile App or a computer with the uPyxis®Desktop App.Figure4.Bluetooth connection to ST-588probe4.5Connecting via USBA USB-RS485adapter(P/N:MA-485)can be used to connect a ST-588probe to a computer with the uPyxis®Desktop App.*NOTE*Using non-Pyxis USB-RS485adapters may result in permanent damage of the ST-588probe communication hardware.B connection to ST-588probe5Setup and Calibration with uPyxis®Mobile App5.1Download uPyxis®Mobile AppDownload uPyxis®Mobile App from Apple App Store or Google Play.Figure6.5.2Connecting to uPyxis®Mobile AppTurn on Bluetooth on your mobile phone(Do not pair the phone Bluetooth to the ST-588probe).Open uPyxis®Mobile App.Once the app is open the app will start to search for the sensor.Once the uPyxis®Mobile App connects to the sensor,press the ST-588probe.Figure7.5.3Calibration Screen and ReadingWhen connected,the uPyxis®Mobile App will default to the Calibration screen.From the Calibration screen,you can perform calibrations by pressing on Zero Calibration,Slope Calibration,and4–20mA Span for either Fluorescent Polymer or PTSA,independently.Follow the screen instructions for each calibration step.Figure8.5.4Diagnosis ScreenFrom the Diagnosis screen,you can check the diagnosis condition.This feature may be used for technical support when communicating with*********************.To preform a probe cleaniness check,first select the Diagnosis Condition which defines the fluid type that the ST-588probe in currently measuring,then press Cleanliness Check.If the probe is clean,a Clean mes-sage will be shown.If the probe is severely fouled,a Dirty message will be shown.In this case,follow the procedure in the Methods to Cleaning the ST-588section of this manual.Figure9.5.5Device Info ScreenFrom the Device Info screen.You can name the Device or Product as well as set the Modbus address.Figure10.6Setup and Calibration with uPyxis®Desktop App6.1Install uPyxis®Desktop AppDownload the latest version of uPyxis®Desktop software package from:https:///upyxis/this setup package will download and install the Framework4.5(if not previously installed on the PC),the USB driver for the USB-Bluetooth adapter(MA-NEB),the USB-RS485adapter(MA-485),and the main uPyxis®Desktop application.Double click the uPyxis.Setup.exe file to install.Figure11.Click Install to start the installation process.Follow the screen instructions to complete the USB driver and uPyxis®installation.6.2Connecting to uPyxis®Desktop AppWhen the uPyxis®Desktop App opens,click on Device,then click either Connect via USB-Bluetooth or Connect via USB-RS485depending on the connection type.Figure12.6.3Information ScreenOnce connected to the device,a picture of the device will appear on the top left corner of the window and the uPyxis®Desktop App will default to the Information screen.On the Information screen you can set the information description for Device Name,Product Name,and Modbus Address,then click Apply Settings to save.Figure13.6.4Calibration ScreenTo calibrate the device,click on Calibration.On the Calibration screen there are six calibration options:•Fluorescent Polymer:Zero Calibration,Slope Calibration,and4-20mA Span•PTSA:Zero Calibration,Slope Calibration,and4-20mA SpanThe screen also displays the reading of the device.The reading refresh rate is every4seconds.Figure14.6.5Diagnosis ScreenAfter the device has been calibrated and installation has been completed,to check diagnosis,click on Di-agnosis.When in the Diagnosis screen you can view the Diagnosis Condition of the device.This feature may be used for technical support when communicating with*********************.To preform a probe Cleaniness Check,first select the Diagnosis Condition which defines the fluid type that the ST-588probe inCheck.If the probe is clean,a Clean message will be shown.message will be shown.In this case,follow the procedure in theof this manual.Figure15.7Outputs7.14–20mA Output SetupThe4–20mA output of the ST-588sensor is scaled as:•Fluorescent Polymer:–4mA=0ppm–20mA=20ppm•PTSA:–4mA=0ppb–20mA=200ppb7.2Communication using Modbus RTUThe ST-588probe is configured as a Modbus slave device.In addition to the ppm Fluorescent Polymer and ppb PTSA values,many operational parameters,including warning and error messages,are available via a Modbus RTU connection.Contact Pyxis Lab Customer Service(*********************)for more informa-tion.8Sensor Maintenance and PrecautionThe ST-588probe is designed to provide reliable and continuous Fluorescent Polymer and PTSA readings even when installed in moderately contaminated industrial cooling waters.Although the optics are com-pensated for the effects of moderate fouling,heavy fouling will prevent the light from reaching the sensor, resulting in low readings and the potential for product overfeed if the ST-588probe is used as part of an au-tomated control system.When used to control product dosing,it is suggested that the automation system be configured to provide backup to limit potential product overfeed,for example by limiting pump size or duration,or by alarming if the pumping rate exceeds a desired maximum limit.The ST-588probe is designed to be easily removed,inspected,and cleaned if required.It is suggested that the ST-588probe be checked for fouling and cleaned/calibrated on a monthly basis.Heavily contam-inated waters may require more frequent cleanings.Cleaner water sources with less contamination may not require cleaning for several months.The need to clean the ST-588probe can be determined by the Cleanliness Check using either the uPyxis®Mobile App(see the Mobile Diagnosis Screen section)or the uPyxis®Desktop App(see the Desktop Diagnosis Screen section).8.1Methods to Cleaning the ST-588Any equipment in contact with industrial cooling systems is subject to many potential foulants and con-taminants.Our inline probe cleaning solutions below have been shown to remove most common foulants and contaminants.A small,soft bristle brush,Q-Tips cotton swab,or soft cloth may be used to safely clean the probe housing and the quartz optical sensor channel.These components and more come with a Pyxis Lab Inline Probe Cleaning Solution Kit(P/N:SER-01)which can be purchased at our online Estore/Catalog https:///product/probe-cleaning-kit/Figure16.Inline Probe Cleaning Solution KitTo clean the ST-588probe,soak the lower half of the probe in100mL inline probe cleaning solution for 10minutes.Rinse the ST-588probe with distilled water and then check for the flashing blue light inside the ST-588probe quartz tube.If the surface is not entirely clean,continue to soak the ST-588probe for an e the small,soft bristle brush and Q-Tips cotton swabs as necessary to remove any remaining contaminants in the ST-588probe quartz tube.8.2StorageAvoid long term storage at temperature over100°F.In an outdoor installation,properly shield the ST-588 probe from direct sunlight and precipitation.9TroubleshootingIf the ST-588probe output signal is not stable and fluctuates significantly,make an additional ground con-nection––connect the clear(shield,earth ground)wire to a conductor that contacts the sample water electrically such as a metal pipe adjacent to the ST-588tee.Carry out routine calibration verification against a qualified Fluorescent Polymer and PTSA combined stan-dard.After properly cleaning the ST-588sensor,carry out the zero point calibration with distilled water and slope calibration using the qualified Fluorescent Polymer and PTSA combined standard.10Contact UsPyxis Lab,Inc1729Majestic Dr.Suite5Lafayette,CO80026USAPhone:+1(866)203-8397Email:*********************。
Mepsevii (vestronidase alfa-vjbk) 产品说明书
Mepsevii® (vestronidase alfa-vjbk)(Intravenous)Document Number: IC-0346 Last Review Date: 03/31/2023Date of Origin: 12/12/2017Dates Reviewed: 12/2017, 10/2018, 02/2019, 02/2020, 02/2021, 02/2022, 02/2023, 04/2023I.Length of AuthorizationCoverage will be provided for 12 months and may be renewed.II.Dosing LimitsA.Quantity Limit (max daily dose) [NDC Unit]:•Mepsevii 10 mg/5 mL vial: 46 vials per 14 daysB.Max Units (per dose and over time) [HCPCS Unit]:•460 billable units (460 mg) every 14 daysIII.Initial Approval Criteria 1Coverage is provided in the following conditions:•Patient is at least 5 months of age; AND•Documented baseline age-appropriate values for one or more of the following have been obtained: 6-minute walk test (6-MWT), motor function [i.e., Bruininks-Oseretsky Test ofMotor Proficiency (BOT-2)], liver and/or spleen volume, urinary excretion ofglycosaminoglycans (GAGs) such as chondroitin sulfate and dermatan sulfate, skeletalinvolvement (i.e. Z-score), pulmonary function tests, shoulder flexion, visual acuity, etc.;AND**NOTE: For very young patients in which FVC or 6-MWT are not suitable for measuring, requests will be reviewed on a case-by case basis.Universal Criteria 1•Therapy is being used to treat non-central nervous system manifestations of mucopolysaccharidosis VII (MPS VII); AND•Patient has a definitive diagnosis of MPS VII as confirmed by BOTH of the following:Mucopolysaccharidosis VII (MPS VII; Sly Syndrome) † Ф 1,2o Beta-glucuronidase enzyme deficiency in peripheral blood leukocytes; ANDo Detection of pathogenic mutations in the GUSB gene by molecular genetic testing † FDA-approved indication(s); ‡ Compendia recommended indication(s); Ф Orphan Drug IV.Renewal Criteria 1,2Coverage may be renewed based on the following criteria:•Patient continues to meet the universal and other indication-specific relevant criteria such as concomitant therapy requirements (not including prerequisite therapy), performancestatus, etc.identified in section III; AND•Absence of unacceptable toxicity from the drug. Examples of unacceptable toxicity include: anaphylaxis and severe allergic reactions, etc.; AND•Patient has demonstrated a beneficial response to therapy compared to pretreatment age-appropriate baseline values in one or more of the following:o Stability or improvement in 6-MWT, shoulder flexion, visual acuity, and/or other motor functionso Reduction in liver and/or spleen volumeo Reduction in urinary excretion of GAGso Stability of skeletal disease (i.e. improvement in Z-score)o Stability or improvement in pulmonary function tests, etc.V.Dosage/Administration 1VI.Billing Code/Availability InformationHCPCS Code:•J3397 − Injection, vestronidase alfa-vjbk, 1 mg: 1 billable unit = 1 mgNDC:•Mepsevii 10 mg/5 mL single-dose vial: 69794-0001-xxVII.References1.Mepsevii [package insert]. Novato, CA; Ultragenyx Pharmaceutical Inc.; December 2020.Accessed March 2023.2.Montaño AM, Lock-Hock N, Steiner RD, et al. Clinical course of sly syndrome(mucopolysaccharidosis type VII). J Med Genet. 2016 Jun;53(6):403-18.3.Harmatz P, Whitley CB, Wang RY, et al. A novel, randomized, placebo-controlled, blind-start, single-crossover phase 3 study to assess the efficacy and safety of UX003 (rhGUS)enzyme replacement therapy in patients with MPS VII. Mol Genet Metab. 2017;120:S63.4.Qi Y, McKeever K, Taylor J, et al. Pharmacokinetic and Pharmacodynamic Modeling toOptimize the Dose of Vestronidase Alfa, an Enzyme Replacement Therapy for Treatment ofPatients with Mucopolysaccharidosis Type VII: Results from Three Trials. ClinPharmacokinet. 2019 May;58(5):673-683. doi: 10.1007/s40262-018-0721-y.Appendix 1 – Covered Diagnosis CodesAppendix 2 – Centers for Medicare and Medicaid Services (CMS)Medicare coverage for outpatient (Part B) drugs is outlined in the Medicare Benefit Policy Manual (Pub. 100-2), Chapter 15, §50 Drugs and Biologicals. In addition, National Coverage Determination (NCD), Local Coverage Determinations (LCDs), and Local Coverage Articles may exist and compliance with these policies is required where applicable. They can be found at: https:///medicare-coverage-database/search.aspx. Additional indications may be covered at the discretion of the health plan.Medicare Part B Covered Diagnosis Codes (applicable to existing NCD/LCD/LCA): N/A。
台湾制造DUAL INPUT RTD 四位数数字温度计说明书
MADE IN TAIWANOPERATING INSTRUCTIONSHH804UDUAL INPUT RTD THERMOMETERINTRODUCTION This instrument is a 4_digit,compact-sized portable digital thermometer designed to use external 100_Platinum RTD as temperature sensor.Tem-perature indication follows Reference Temperature/Resistance Tables (Pt385for European Curve,Alpha=.00385.Pt3926for American Curve,Al pha=.003926. Pt3916 for Japan Curve, Alpha=.003916.)SAFETY INFORMATIONIt is recommended that you read the safety and operation instructions before using the thermometer.WARNINGTo avoid electrical shock, do not use this instrument when working voltagesat the measurement surface over 24V AC or DC.WARNINGTo avoid damage or burns, do not take temperature measurements in micro-wave ovens.ENVIRONMENTALAmbient Operating Ranges:0°C to 50°C (32°F to 122°F) <70% R.H.Storage Temperature:-20°C to 60°C (-4°F to 140°F) <80% R.H.GENERALDisplay:4_ digit liquid crystal display (LCD) with maximum reading of 19999Overload:“----.-“ or “OL” is display.Battery:1.5V x 4 PCS (SIZE AAA) R03P.Battery Life:200 hours typical with carbon zinc battery Auto power off: 30 minutes Dimensions:160mm(H) x83mm(W) x 38mm(D)Weight:Approx. 255g including batteries.SPECIFICATIONSELECTRICALTemperature Scale: Celsius or Fahrenheit user-selectable Measurement Range:Pt385(100_) -200°C to 800°C, (-328°F to 1472°F)Pt3916/Pt3926(100_) -200°C to 630°C, (-328°F to 1166°F)Resolution:0.1°C or 0.2°F Accuracy:Accuracy is specified for operating temperatures over the range of 18°C to 28°C (64°F to 82°F), for 1 year, not including RTD probe error.±(0.05% rdg + 0.2°C) on °C scale ±(0.05% rdg + 0.4°F) on °F scale Temperature Coefficient:0.1 times the applicable accuracy specification per °C from 0°C to 18°C and 28°C to 50°C (32°F to 64°F and 82°F to 122°F).Input Protection:24V dc or 24V ac rms maximum input voltage on any combination of input pins.Maximum Differential Common Mode Voltage (Maximum Voltage be-tween T1 and T2 during measurement): 1volt.Reading Rate: 1sample/second.Input Connector:Accepts 4 pin mini-DIN connectors.OPERATING INSTRUCTIONS1.Power ButtonThebutton turns the thermometer on or off. In the SET mode the unit cannot be powered off. Exit the SET mode to power off.APO function modePress “”power button for more than 6seconds to disable auto power function. The display will show “APO OFF”.2.°C/°F Selecting the Temperature Scale (Main display)Readings are displayed in either degrees Celsius(°C) or degrees Fahren-heit(°F). When the thermometer is turned on, it is set to the temperature scale that was in use when the thermometer was last turned off. To change the temperature scale, press the °C/°F key.3. “ ” Display Back-LightPress the “ ” key to turn on or turn off the back light.4. T1 T2/T1-T2 Main display Input SelectionThe input selection button determines which input is shown on the display;T1,T2or the difference between the two probes (T1-T2).When thermometer is turned on, it is set to T1.5. TYPE(Pt385/Pt3926/Pt3916) Input RTD Probe Select (Main display)The TYPE button selects the RTD curve to use for the input currently shown.When the thermometer is turned on,it is set to the curve that selected when the thermometer was last turned off.6. MIN MAX with Time record Mode (only Main display)Press MIN MAX key to enter the MIN MAX Recording mode,(displays Maximum reading with time,Minimum reading with time and Average reading stored in recording mode).In the this mode the automatic power-off feature is disabledand key,°C/°F key,REL key,SET key,Hi/Lo Li key and main display T1T2T1-T2key,TYPE key are disabled.beeper emits a tone when a new minimum or maximum value is recorded.Push MIN MAX key to cycle through the MAX, MIN and AVG readings.If an overload is recorded,the averaging function is Stopped.In the mode,press HOLD key to stop the recording of readings,all values are zen,press again to restart recording.To prevent accidental loss of MAX and AVG data,in this mode can only be cancelled by pressing hold down the MIN MAX key for 2seconds to exit and erased recorded readings.7. REL Relative mode (only Main display)Press REL key to enter the Relative mode,zero the display,and store displayed Reading as a reference value and annunciator REL is displayed.Press REL key again to exit the relative mode.The relative value can be entered by the user.(See “SET mode”later in this manual.)When the sired Relative value has been entered,press REL key to enter the Relative mode,press SET key use set Relative value as a reference value.Press key again to exit the relative mode.In the Relative mode,the value (can >±1999.9counts)shown on the LCD is always the difference between stored reference and the present reading.8.HOLD Mode (only Main display)Press the HOLD key to enter the Data Hold mode,the “HOLD”annunciator is displayed.When HOLD mode is selected,the thermometer held the sent readings and stops all further measurements.Press the HOLD again to cancel HOLD mode causing thermometer to resume taking ureents.In the MIN/MAX recording mode,press HOLD key to stop the cording.Press HOLD key again to resume recording.(Previously recorded read are not erased).9. SET mode (Relative value set, Time set and Hi/Lo Limits value set)Press SET key to enter Relative values SET mode (Press ENTER key escape relative values set mode),REL set mode.====.=is displayed main display.Relative value is entered via overlay numbers,thenHH804UOMEGAnet ®On-Line ServiceInternet e-mail **************Czech Republic:Frystatska 184, 733 01 Karvina ´, Czech Republic Tel: +420 (0)59 6311899FAX: +420 (0)59 6311114Toll Free: 0800-1-66342e-mail:*****************Germany/Austria:Daimlerstrasse 26, D-75392 Deckenpfronn, Germany Tel: +49 (0)7056 9398-0 FAX: +49 (0)7056 9398-29TollFreeinGermany************e-mail:*************Servicing Europe:U.S.A. and Canada:Sales Service: 1-800-826-6342/1-800-TC-OMEGA Customer Service: 1-800-622-2378/1-800-622-BEST Engineering Service: 1-800-872-9436/1-800-USA-WHEN U.S.A.: ISO 9001 Certified One Omega Drive, Box 4047Stamford, CT 06907-0047Tel: (203) 359-1660FAX: (203) 359-7700e-mail:**************Servicing North America:For immediate technical or application assistance:Mexico:En Espan~ol: (001) 203-359-7803FAX: (001) 203-359-7807e-mail:*******************************.mxUnited Kingdom ISO 9002 Certified One Omega DriveRiver Bend Technology Centre Northbank, Irlam Manchester M44 5BD United KingdomTel: +44 (0)161 777 6611 FAX: +44 (0)161 777 6622Toll Free in United Kingdom: 0800-488-488e-mail:**************.ukCanada:976 BergarLaval (Quebec) H7L 5A1, Canada Tel: (514) 856-6928FAX: (514) 856-6886e-mail:*************Where Do I Find Everything I Need for Process Measurement and Control?OMEGA…Of Course!Shop online at M4501/0607TEMPERATUREⅪߜThermocouple, RTD & ThermistorProbes, Connectors, Panels &Assemblies ⅪߜWire: Thermocouple, RTD &Thermistor ⅪߜCalibrators & Ice Point References ⅪߜRecorders, Controllers & ProcessMonitors ⅪߜInfrared PyrometersPRESSURE, STRAIN AND FORCEⅪߜTransducers & Strain GagesⅪߜLoad Cells & Pressure Gages ⅪߜDisplacement Transducers ⅪߜInstrumentation & AccessoriesFLOW/LEVELⅪߜRotameters, Gas Mass Flowmeters &Flow Computers ⅪߜAir Velocity Indicators ⅪߜTurbine/Paddlewheel Systems ⅪߜTotalizers & Batch ControllerspH/CONDUCTIVITYⅪߜpH Electrodes, Testers & Accessories ⅪߜBenchtop/Laboratory Meters ⅪߜControllers, Calibrators, Simulators &Pumps ⅪߜIndustrial pH & ConductivityEquipmentDATA ACQUISITIONⅪߜData Acquisition & EngineeringSoftware ⅪߜCommunications-Based AcquisitionSystems ⅪߜPlug-in Cards for Apple, IBM &Compatibles ⅪߜDatalogging Systems ⅪߜRecorders, Printers & PlottersHEATERSⅪߜHeating CableⅪߜCartridge & Strip Heaters ⅪߜImmersion & Band Heaters ⅪߜFlexible Heaters ⅪߜLaboratory HeatersENVIRONMENTALMONITORING AND CONTROLⅪߜMetering & Control InstrumentationⅪߜRefractometers ⅪߜPumps & TubingⅪߜAir, Soil & Water Monitors ⅪߜIndustrial Water & Wastewater Treatment ⅪߜpH, Conductivity & Dissolved OxygenInstrumentsRETURN REQUESTS/INQUIRIESDirect all warranty and repair requests/inquiries to the OMEGA Customer Service Department.BEFORE RETURNING ANY PRODUCT(S) TO OMEGA, PURCHASER MUST OBTAIN AN AUTHORIZED RETURN (AR) NUMBER FROM OMEGA’S CUSTOMER SERV ICE DEPARTMENT (IN ORDER TO AV OID PROCESSING DELAYS). The assigned AR number should then be marked on the outside of the return package and on any correspondence.The purchaser is responsible for shipping charges, freight, insurance and proper packaging to prevent breakage in transit.FOR WARRANTY RETURNS, please have the following information available BEFORE contacting OMEGA:1.Purchase Order number under which the product was PURCHASED,2.Model and serial number of the product under warranty, and3.Repair instructions and/or specific problems relative to the product.FOR NON-WARRANTY REPAIRS,consult OMEGA for current repair charges. Have the following information available BEFORE contacting OMEGA:1. Purchase Order number to cover the COST of the repair,2.Model and serial number of the product, and3.Repair instructions and/or specific problems relative to the product.WARRANTY/DISCLAIMEROMEGA ENGINEERING, INC. warrants this unit to be free of defects in materials and workmanship for a period of 13 months from date of purchase. OMEGA’s WARRANTY adds an additional one (1) month grace period to the normal one (1) year product warranty to cover handling and shipping time. This ensures that OMEGA’s customers receive maximum coverage on each product.If the unit malfunctions, it must be returned to the factory for evaluation. OMEGA’s Customer Service Department will issue an Authorized Return (AR) number immediately upon phone or written request. Upon examination by OMEGA, if the unit is found to be defective, it will be repaired or replaced at no charge. OMEGA’s WARRANTY does not apply to defects resulting from any action of the purchaser, including but not limited to mishandling,improper interfacing, operation outside of design limits, improper repair, or unauthorized modification. This WARRANTY is VOID if the unit shows evidence of having been tampered with or shows evidence of having been damaged as a result of excessive corrosion; or current, heat, moisture or vibration; improper specification; misapplication; misuse or other operating conditions outside of OMEGA’s control. Components in which wear is not warranted, include but are not limited to contact points, fuses, and triacs.OMEGA is pleased to offer suggestions on the use of its various products.However, OMEGA neither assumes responsibility for any omissions or errors nor assumes liability for any damages that result from the use of its products in accordance with information provided by OMEGA, either verbal or written.OMEGA warrants only that the parts manufactured by the company will be as specified and free of defects. OMEGA MAKES NO OTHER W ARRANTIES OR REPRESENTATIONS OF ANY KIND W HATSOEVER, EXPRESSED OR IMPLIED,EXCEPT THAT OF TITLE, AND ALL IMPLIED W ARRANTIES INCLUDING ANY WARRANTY OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE HEREBY DISCLAIMED. LIMITATION OF LIABILITY: The remedies of purchaser set forth herein are exclusive, and the total liability of OMEGA with respect to this order, whether based on contract, warranty, negligence, indemnification, strict liability or otherwise, shall not exceed the purchase price of the component upon which liability is based. In no event shall OMEGA be liable for consequential,incidental or special damages.CONDITIONS: Equipment sold by OMEGA is not intended to be used, nor shall it be used: (1)as a “Basic Component” under 10 CFR 21 (NRC), used in or with any nuclear installation or activity; or (2) in medical applications or used on humans. Should any Product(s) be used in or with any nuclear installation or activity, medical application, used on humans, or misused in any way, OMEGA assumes no responsibility as set forth in our basic WARRANTY /DISCLAIMER language, and, additionally, purchaser will indemnify OMEGA and hold OMEGA harmless from any liability or damage whatsoever arising out of the use of the Product(s) in such a manner.he policy of OMEGA Engineering, Inc. to comply with all worldwide safety and EMC/EMI ations that apply. OMEGA is constantly pursuing certification of its products to thepean New Approach Directives. OMEGA will add the CE mark to every appropriate device certification.nformation contained in this document is believed to be correct, but OMEGA accepts no ty for any errors it contains, and reserves the right to alter specifications without notice.NING: These products are not designed for use in, and should not be used for, human cations.OMEGAʼs policy is to make running changes, not model changes, whenever an improvement is possible. This affords our customers the latest in technology and engineering.OMEGA is a registered trademark of OMEGA ENGINEERING, INC.© Copyright 2007 OMEGA ENGINEERING, INC. All rights reserved. This document may not be copied, photocopied, reproduced, translated, or reduced to any electronic medium or machine-readable form, in whole or in part, without the prior written consent of OMEGA ENGINEERING, INC.overlay ENTER key, stored the relative value, enter Time set mode.Time set mode,(Press ENTER key can escape Time set mode)=.===:==is displayed in second and third display.Time (hours,minutes,seconds)value is entered via overlay numbers,then press overlay ENTER key.Time start from set time value, enter Hi/Lo Limits value set mode.Hi Limit value set mode,(Press ENTER key can escape Hi Limit value set mode),====.=is displayed in main display,Hi Limit value is entered via overlay numbers,then press overlay ENTER key,stored the Hi Limit value,enter Lo Limit value set mode (Press ENTER key can escape Lo Limit value set mode).====.=is displayed in main display,Lo Limit value is entered via overlay numbers,then press overlay ENTER key,stored the Lo Limit value and exit SET mode.When the thermometer is turned on.The Relative set value and Hi/Lo Limits set value that was in use when thermometer was last turned off set values.T1/T2 T1-T2 second display Input Selectionhe input selection button determines which input is shown on the second splay;T1,T2or the difference between the two probes (T1-T2).When the ermometer is turned on, it is set to T2.TYPE(Pt385/Pt3926/Pt3916) Input RTD Probe select (second display)he TYPE button selects the RTD curve to use for the input currently own.When the thermometer is turned on,it is set to the curve that was lected when the thermometer was last turned off.Hi/Lo Limits mode (only Main display)ess the Hi/Lo Limits button to enter the Hi/Lo Limits comparative mode,hen the input temperature exceeds the Hi or Lo Limits value,the beeper mits a continuous pulse tone.Press the Hi/Lo Limits button again to exit e Hi/Lo Limits mode.TD PROBE CONNECTIONMPERATURE VS RESISTANCE TABLE(ITS90)°C Pt385Pt3926Pt3916-200°C 18.521_16.996_17.057_-100°C 60.256_59.479_59.565_0°C 100.000_100.000_100.000_100°C 138.505_139.272_139.171_200°C 175.856_177.362_177.155_300°C 212.052_214.275_213.957_400°C 247.092_250.018_249.584_500°C 280.977_284.591_284.036_600°C 313.708_317.994_317.313_700°C 345.280_--800°C 375.700_--OPERATOR MAINTENANCEWARNINGTo avoid possible electrical shock, disconnect the thermocouple connectorsfrom the thermometer before removing the cover.Battery Replacement1. Power is supplied by 4pcs 1.5V (SIZE AAA) R03P.2. The “” appears on the LCD display when replacement is needed. Toreplace battery remove screw from back of meter and lift off the battery cover.3. Remove the battery from battery contacts and replace.4. When not in use for long periods the batteries should be removed.5. Do not store in locations with high temperatures, or high humidity.CleaningPeriodically wipe the case with a damp cloth and detergent, do not use abra sives or solvents.V1. 040307。
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Product Name:
Betrixaban CAS No.:
330942-05-7Cat. No.:
HY-10268MWt:
451.91Formula:
C23H22ClN5O3Purity :>98%
Solubility:Mechanisms:
Biological Activity:
Pathways:Metabolism/Protease; Target:Factor Xa Product Data Sheet
DMSO
References:
Caution: Not fully tested. For research purposes only
Medchemexpress LLC
[1]. Zhang P, et al. Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally
efficacious factor Xa inhibitor. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2179-85.[2]. Turpie AG, et al. A randomized evaluation of betrixaban, an oral factor Xa inhibitor, for
prevention of thromboembolic events after total knee replacement (EXPERT). Thromb Haemost.
2009 Jan;101(1):68-76.[3]. Palladino M, et al. Evaluation of the oral direct factor Xa inhibitor - betrixaban. Expert Opin
Investig Drugs. 2013 Nov;22(11):1465-72.Betrixaban (PRT-054021) is a highly potent, selective, and orally efficacious factor Xa inhibitor with
IC50 of 1.2 nM(inhibition of Factor 10a).
IC50 value: 1.2 nM [1]
Target: Factor Xa Betrixaban (PRT-054021) is an anticoagulant drug which acts as a direct factor Xa inhibitor. It is potent, orally active and highly selective for factor Xa, being selected from a group of similar
compounds for its low hERG affinity. Betrixaban has undergone human clinical trials for prevention of embolism after knee surgery, and prevention of stroke following atrial fibrillation, with promising
results.Betrixaban, the fifth novel oral anticoagulant in line for the Food and Drug Administration (FDA)approval, possesses some unique pharmacokinetic characteristics in comparison with the currently available novel anticoagulants, including limited renal excretion, minimal metabolism throu... 18 W i l k i n s o n W a y , P r i n c e t o n , N J 08540,U S A
E m a i l : i n f o @m e d c h e m e x p r e s s .c o m W e b : w w w .m e d c h e m e x p r e s s .c o m。