盐酸丙帕他莫不同用药时机对术后镇痛的影响

盐酸丙帕他莫不同用药时机对术后镇痛的影响
幸芳;曹利艳
【期刊名称】《中国医药指南》
【年(卷),期】2013(11)20
【摘要】Objective To investigate the effect of different time administration of Porpacetamol hydrgqhloride on the postoperative analgesic efifcacy in patients undergoing abdominal operations. Methods Sixty patients undergoing abdominal surgery were randomly allocated to A and B groups(n=30 each). Group A received iv Porpacetamol hydrgqhloride 2g at 15 min before skin incision while group B received iv Porpacetamol hydrgqhloride 2g at 15 min before the end of operation. All the patients received patient-controlled intravenous analgesia with sufentanil. All the patients were followed up after operation. The times of PCIA in 12h and 24h post-operation, VAS score at the time of 2h, 4h, 6h, 12h, 24h post-operation were recorded. Results Compared with group B, the times of PCIA in 12h and 24h post-operation was signiifcantly reduced and VAS score at the time of 2h, 4h, 6h, 12h, post-operation decreased in group A (P<0.05). There was no signiifcant difference in VAS score at the time of 24h between the two groups (P>0.05). Conclusion Porpacetamol hydrgqhloride preemptive analgesia in patients undergoing abdominal operations can assist the postoperative analgesic efifcacy and reduce the sufentanil consumption.% 目的探讨盐酸丙帕他莫不同给药时机对手术患者
术后镇痛效果的影响。

方法择期腹部手术患者60例，随机分为A和B组
（n=30）。

A组切皮前15min静脉滴注2g盐酸丙帕他莫，B组术毕前15min
静脉滴注2g盐酸丙帕他莫。

两组患者术后48h内均使用舒芬太尼行自控静脉镇
痛（PCIA）。

术后随访，记录术后12h和24h患者PCIA的按压次数，及术后2、4、6、12、24h的疼痛视觉模拟（VAS ）评分。

结果与B组相比，A组术后12h 和24h PCIA按压次数明显减少（P<0.05），且术后2、4、6、12h VAS评分显
著降低（P<0.05）。

两组患者24h VAS评分无统计学差异（P>0.05）。

结论腹
部手术超前应用盐酸丙帕他莫，能有效提高患者术后镇痛效果，减少舒芬太尼的用量。

【总页数】2页(P408-409)
【作者】幸芳;曹利艳
【作者单位】郑州大学附属肿瘤医院麻醉科，河南郑州450008;郑州大学附属肿
瘤医院麻醉科，河南郑州450008
【正文语种】中文
【中图分类】R614
【相关文献】
1.格拉司琼不同用药方式对术后镇痛后恶心、呕吐疗效的影响 [J], 谭泽龙;陈淼
2.氟比洛芬酯和帕瑞昔布钠不同给药时机对老年妇科子宫全切术术后镇痛及认知功能的影响 [J], 康凯;王玥;卓亚;刘野;李杉;黄海凝
3.不同用药方式对昂丹司琼预防术后镇痛后恶心、呕吐疗效的影响 [J], 努尔买买
提江?买合木提;胡建军;穆哈塔尔?热西提
4.塞来昔布不同给药时机对下肢开放性骨折患者术后镇痛效果的影响 [J], 祁林青;杨娟;周婷;唐雯雯;陈晓彤
5.氟比洛芬酯不同给药时机对妇科腹腔镜术后镇痛效果的影响 [J], 安小虎;徐韬;余大松
因版权原因，仅展示原文概要，查看原文内容请购买。