TrendsinChineseChemicalResearch.ppt
化学文献检索讲义ppt课件
公司名称组织
普通主题索引及化学物质索引说明语的阅读:
在化学物质索引和普通主题索引中有大量的说明语, 这些说明语对索引标题起说明和解释作用。一般来说, 说明语是带有介词的词组,伴有不少逗号,各说明语 之间有一定的语法关系,阅读时,必须尽量使句子通 顺。但如果了解说明语之间逗号的使用规则,对说明 语阅读一定会有帮助。逗号在说明语中所起的作用主 要有以下三个方面:
公司名称组织
(3)取代基副标题 取代基副标题与上述两类副标题不同,它 是将取代基连在母体化合物标题后而构成新的化合物标题。取 代基按字顺排列,例如: Benzoic acid ——, 4-bromo-[586-76-5] ——, 2-methoxy-[100-09-4] ——, 2, 4, 6-trihydroxy-[16534-78-4]
饰性副标题:
公司名称组织
1、 放射性主题下的副标题 biological effects chemical and physical effects
等比双元合金
base 2、 合金主题下 nonbase 不等比合金
原子序数大 ,在base后 原子序数小在nonbase后 组成高的 ,在base后 组成少的,在nonbase后
公司名称组织
分子式索引 著录格式
C8H8O2 Benzaldehyde hydroxymethy [99-57-9], 106: 104728e, 113: 196826 4-hydroxy-3-methyl-[15174-69-3], 107: 36338h, 109: 169962v methoxy-[50984-52-6], see Chemical Substance Index 2-methoxy-[135-02-4], see Chemical ubstance Index
trends in analytical chemistry约稿模板
trends in analytical chemistry约稿模板Title: Trends in Analytical Chemistry: A Comprehensive OverviewIntroduction:Analytical chemistry plays a crucial role in various fields, including pharmaceuticals, environmental sciences, food safety, and forensic science. As technology advances, the field of analytical chemistry continues to evolve and embrace new methodologies and techniques. This article aims to provide a comprehensive overview of the emerging trends in analytical chemistry, highlighting their significance and potential implications.1. Miniaturization:One of the prominent trends in analytical chemistry is the miniaturization of analytical devices and systems. Miniaturization offers several advantages, including lower sample and reagent consumption, reduced analysis time, and portability. Techniques such as microfluidics, lab-on-a-chip, and nanosensors have gained attention due to their ability to perform rapid and sensitive analysis in small volumes. Miniaturization has opened up new possibilities for point-of-care diagnostics, on-site monitoring, and personalized medicine.2. Advanced Mass Spectrometry:Mass spectrometry (MS) has been a key analytical tool for decades, but recent advancements have significantly enhanced its capabilities. High-resolution MS, tandem MS, and ion mobility MS have improved the detection and identification of complexanalytes, including metabolites, proteins, and peptides. Furthermore, the development of ambient ionization techniques has enabled direct analysis of samples in their native environment, eliminating the need for sample preparation. These advancements have revolutionized the fields of metabolomics, proteomics, and omics sciences.3. Big Data and Data Analytics:The advent of big data has had a profound impact on various scientific disciplines, including analytical chemistry. Analytical chemists are now faced with large and complex datasets generated from various analytical techniques. Thus, the need for effective data management, data processing, and data analytics has become increasingly important. Data integration, machine learning algorithms, and chemometrics are being employed to extract meaningful information, identify patterns, and make predictions, leading to better decision-making and optimization of analytical processes.4. Sustainable and Green Analytical Chemistry:With increasing environmental concerns, there is a growing emphasis on sustainable and green analytical chemistry practices. This includes developing eco-friendly sample preparation techniques, reducing waste generation, and utilizing renewable resources. Techniques such as microwave-assisted extraction, supercritical fluid extraction, and solid-phase microextraction are gaining popularity due to their reduced solvent consumption and energy requirements. Additionally, green analytical chemistry involves using environmentally friendly reagents and developing recyclable or biodegradable analytical tools.5. Multi- and Cross-Disciplinary Approaches:Analytical chemistry has always been an interdisciplinary field, but recent trends indicate a shift towards multi- and cross-disciplinary approaches. Collaborations with experts from fields such as materials science, nanotechnology, biology, and computer science have led to significant advancements. Integration of analytical chemistry with these disciplines has resulted in the development of innovative techniques such as plasmonics-based sensing, bioanalytical nanomaterials, and data-driven analytical models, expanding the scope and applicability of analytical chemistry. Conclusion:The field of analytical chemistry is constantly evolving, driven by emerging trends and technological advancements. This article has provided a comprehensive overview of some of the prominent trends, including miniaturization, advanced mass spectrometry, big data analytics, sustainable practices, and cross-disciplinary approaches. It is evident that these trends will continue to shape the future of analytical chemistry and pave the way for novel analytical methods, instruments, and applications.。
中药化学成分概况与研究进展-PPT精选文档
P h P h
O
O H N O
N C H C O N H 2 2 脑 复 康 脑复康
HO H HC 3
黄皮酰胺 ( ) 黄皮酰 ?
(4)钙离子拮抗剂 蝙蝠苏林碱
5. 增强免疫成分
真菌多糖 植物多糖
皂苷类
雷公藤内酯
6 . 抗肝炎活性成分:五味子素、联苯
甘草皂苷硫酸酯化后抑制HIV效果可提高4
倍。 棉酚 大豆皂苷类
(3) 黄酮类 Chrysanthemum morifolim Ramar中的多 种黄酮类化合物有抗HIV活性:
R5 R1O R2 OR3 O O R6 R4
当R1=rha—glu时活性最小 R1=gal时活性最大
R1 R2 R3 R4 O O
michellamine A and B 栗树碱 原小檗碱 吐根碱 九节碱磺酸盐 苯并非啶类
(2)、萜类 Maprounea africana中 发现六个五环三萜
R1 R2 R3
R2
C OOH
我国从华东水杨梅中分得六个有抗HIV作用的三萜
穿心莲中的DASM 华中五味子的nigranoicacid
有抗癌和放疗增敏作用,具无骨髓抑制作用.
总合草苔虫内酯 靛玉红及其衍生物
2.抗心血管疾病药物
北豆根:蝙蝠葛碱(dauncine) 葛根总黄酮 芹菜甲素 银杏内酯 丹参酮ⅡA
黄山药皂苷
蒺藜总皂苷 人参皂苷、三七皂苷、匙羹藤皂苷、生藤皂苷
3.抗HIV活性产物
中药(天然药)有效成分 研究概况与进展
中药(天然药)的历史与有效成分研究
一、19世纪来天然药发展趋势 重视(1900年前):四大传统医药体系为主流医学体系 低潮(1910—1960年):合成药物的兴起;西医药成为主流医学体系 重视(1970年后):重新评价中药、天然药的医学地位 二、转折点 三、原因
chinese chemical letters状态
chinese chemical letters状态Chinese Chemical Letters is a high-quality and peer-reviewed scientific journal that focuses on publishing cutting-edge research in the field of chemistry. It is renowned for its rigorous review process and strong emphasis on scientific rigor and quality. The journal aims to promote communication and collaboration among researchers, and provide a platform for the dissemination of new discoveries and advancements in chemistry.The primary aim of Chinese Chemical Letters is to publish original and significant research articles that contribute to the development of the chemical sciences. The journal covers various sub-disciplines within chemistry, including organic chemistry, inorganic chemistry, physical chemistry, analytical chemistry, materials chemistry, and biochemistry. It welcomes submissions from both Chinese and international researchers.To maintain the high standard of the journal, Chinese Chemical Letters follows a peer-review process. Upon submission, the articles undergo a thorough evaluation by experts in the field. The reviewers assess the quality, accuracy, and significance of the research, and provide constructive feedback to the authors. This rigorous review process ensures that only high-quality and impactful research is published in the journal.Chinese Chemical Letters also places great importance on scientific rigor and ethical conduct. The journal adheres to international publishing standards and guidelines, such as those outlined by the Committee on Publication Ethics (COPE). It expects authors to uphold the highest standards of research integrity and ethics, including the proper citation of sources, accurate reporting of results, and avoidance of plagiarism.In addition to research articles, Chinese Chemical Letters also publishes review articles, highlights, and perspectives. Review articles provide comprehensive overviews of specific topics within chemistry, highlighting the current state of knowledge and future directions. Highlights showcase recent breakthroughs and advancements in the field. Perspectives offer expert opinions and insights into emerging trends and challenges in chemistry.Chinese Chemical Letters is published by the Chemical Industry Press and is available both in print and online formats. The journal has a wide readership, including researchers, academics, and professionals in the field of chemistry. Its articles are widely cited and recognized by the scientific community.In conclusion, Chinese Chemical Letters is a prestigious scientific journal that plays a vital role in advancing the field of chemistry. It provides a platform for the publication of high-quality research and fosters collaboration and communication among researchers. The journal upholds rigorous review standards, promotes scientific rigor and ethics, and covers a range of sub-disciplines within chemistry. With its commitment to excellence, Chinese Chemical Letters continues to be a valuable resource for the chemical sciences community.。
《化学前沿研究动态》课件
新能源材料化学主要研究高效、环保的能源转化和存储材料,如太阳能电池、燃料电池和锂离子电池等。该领域的研究目标是开发具有高能量转化效率和长寿命的新型能源材料,以解决传统能源带来的环境问题。
生物医用化学是化学与生物学、医学等学科交叉的前沿领域,主要涉及药物设计与合成、生物成像技术和生物医用材料的研发。
量子计算利用量子力学的原理进行计算,在处理复杂问题时具有超强的计算能力。
1
2
3
冷冻电镜技术是一种高分辨率的成像技术,可以观察生物和化学分子在自然状态下的结构和行为。
通过冷冻电镜技术,科学家可以观察到分子间的相互作用和化学反应过程,为理解化学反应机制提供了新的视角。
冷冻电镜技术还可以用于药物设计和材料科学等领域,为新药开发和材料性能优化提供了有力支持。
通过机器学习算法,人工智能可以快速筛选出高活性的分子或催化剂,大大缩短了实验的时间和成本。
人工智能还可以帮助科学家理解复杂的化学反应机制,提供更深入的化学知识。
在化学领域,量子计算被用于模拟分子的电子结构和化学反应过程,预测分子的性质和行为。
随着量子计算技术的发展,未来将有可能实现更精确的化学模拟和预测,推动化学研究的进步。
《化学前沿研究动态》ppt课件
CATALOGUE
目录
化学前沿研究概述化学前沿研究的核心领域化学前沿研究的最新进展化学前沿研究的挑战与展望结论
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化学前沿研究概述
总结词
化学前沿研究是指针对当前化学领域中具有挑战性和创新性的问题,采用最新理论和技术手段进行深入研究的过程。其特点包括高度的创新性、跨学科性、高风险性和高回报性。
详细描述
化学前沿研究通常涉及对化学领域中深层次、根本性问题的探索,这些问题往往具有很高的挑战性和难度。研究者需要具备创新思维和跨学科知识,采用最新的理论和技术手段,探索新的化学反应机理、发现新的化合物或材料,为人类社会的发展提供新的解决方案。由于这种研究的难度和风险较高,但成功后可能带来巨大的科学价值和实用价值,因此,化学前沿研述
我国循环经济发展战略与试点研究(ppt 42页)PPT学习课件
Proposal 1: Study on Strategy Framework of Circular Economy Development in
Expected results 预期结果
Objectives(目标):
重要战略机遇期 选择确定了钢铁、有色、煤炭、电力、化工、建材、轻工7个重点行业,依托42家企业开展试点
估计未来主要资源的需求及2020年GDP翻两番时大量资源消费对环境的潜在影响;
建立和完善再生资源回收网络,明确回收处理技术路线,提出再生资源循环利用模式;
•城市化进程加速
Building new economic growth pattern 探索新的经济增长方式
• To achieve China’s strategic goal of quadrupling its GDP by 2020 with least possible resource consumption and less environmental and ecological deterioration 以最少的资源消费和较小的环境和生态破坏实现2020年GDP 翻两番的战略目标
社 元,低收入国家 时期 生态环境形势严峻 任务C:确定资源节约、再利用和资源化的关键技术 会 经国务院同意,国家发改委会同环保总局等有关部门和省级人民政府,在重点行业、重点领域、产业善再生资源回收利用体系,建立资源循环利用机制;
中国化学原料药(API)行业介绍ppt课件
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国外称重应用现场
Hazardous Area
Class I-III/Div 2
Safe area
25
国外称重应用现场
Zone 2/22
Zone 1/21 Class I-III/Div 1
Centerlign
220-20‘000kg
Flexmount
220-90‘000kg
Ringmount
4 : 放料/填充/定量 进入反应堆
7 : 桶灌装/袋包装称重
16
在那里有多少称重应用 ?
1 2
3 5
4
5
56
Dryer
6
7
通常, 在MPU里最少有 2-5 台秤. (有时会用 10-15台)
• 通常, 固体 1和气体反应物 2是一定要称量的 (地上衡上 – 为了提高精 度,不用移动式秤)
• 液体反应物 3 是同样需要称重的, 因为他们准确与否将会影响反应出
EX
30
细分市场
Trojan Horses
集中我们的 力量 in
PHCHEM
No competitor is strong in: 质量, 流程/物流, 安全, 和生产力 !
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药的市场价格 ~ 90‘000 $ / kg
中间体: 他是在API合成过程中通过进一步的分子变化或者是纯化, 直到到他转化为API.可能并不经过提炼/分离.
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我们的应用
反应物处于临时“开放“系统中 被填充或计量产品
主要的称重应用里
区 1 (21)
都有防爆要求
Ex
等 I-III/Div 1
1
2
3 5
Biotech Formulation & Packing
《化学化工专业英语》文献摘要讲解PPT
中药化学PPT课件
二、苷类化合物
(二)苷类化合物的分类: 根据生物体内的存在形式:分为原生苷(原存在于植物体内的苷)、次生苷(原
生苷水解失去一部分糖后生成的苷)。 根据苷元的结构:黄酮苷、蒽醌苷、香豆素苷等。 根据苷键原子的不同:氧苷、硫苷、氮苷、 碳苷。
第25页/共174页
O
OH
O
OH
O
-
N OSO3 O S C CH2CH2 CH CH S CH3
4. 大孔树脂色谱
• 色谱原理:通过物理吸附有选择性地吸附有 机物质而达到分离。
• 大孔吸附树脂分类:可分为非极性(适宜分 离极性小的成分)、中等极性(适宜分离极 性较大的成分)与极性三类。
• 分离结果:对于非极性的树脂,洗脱剂的极 性越小,其洗脱能力越强。
第19页/共174页
三、中药有效成分的分离精制方法—色谱分离法
5. 分配色谱
• 色谱原理:利用被分离成分在固定相和流动相之间的分 配系数的不同而达到分离。 • 分类:正相分配色谱 流动相极性<固定相极性
常用的固定相有氰基与氨基键合相,主要用于分离极性 及中等极性的分子型物质。
反相分配色谱 流动相极性>固定相极性 常用的固定相有十八烷基硅烷(ODS)或C8键合相, 主要用于分离非极性及中等极性的各类分子型物质。流 动相常用甲醇-水或乙腈-水。
残留物 EtOAc 提取
EtOAc 提取液
残留物
(含单糖苷或含糖较少的苷)
n-BuOH 提取
第31页/共174页n-BuOH 提取液(含糖较多的苷)
四、糖和苷类的检识
1、α-萘酚浓硫酸反应(Molish反应) 现象:两液层界面呈现紫红色环 适用于:单糖、低聚糖、多糖和苷类,可用于区别苷和苷
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September 11th, 2006 San Francisco
Dani Xu
OriProbe Information Services, Canada
Song Yu
Columbia University Libraries, USA
5
Main Progress in Chinese Chemical Research
1. Nanotechnology
❖ 1990-2002, nearly1000 projects, with $27 million funding were implemented. [1]
❖ Developments encompasses nanodevices, nanobiology& medicine, detection & characterization, modeling and simulation [1]
2
Overview of Chinese Chemical research Development
▪ Figure shows the increase of China’s Citation rate for publications with a Chinese address for the first author during the preceding ten years.
[4] K Jiang, Q Li, S Fan, Spinning continuous carbon nanotube yarns, NATURE, 2002, 419, 801
6
Main Progress in Chinese Chemical Research
1. Nanotechnology (continued)
4
Overview of Chinese Chemical research Development
❖ China is actively involved in the research of [1,2,3,4]
❖ Materials synthesis and characterization (e.g. catalysts and nano-materials),
Dr. Danny Dingfei Liu Wanfang Data Corporation,
Institute of Scientific and Technical Information of China (ISTIC), China
Presentation Outline:
❖ Overview of Chinese Chemical research Development
❖ Asymmetric catalyzed reactions in organic chemistry ❖ Structure determination data acquiring ❖ Software suite for macromolecular structure determination
[2} China Science Citation Index, /, August 30, 2006
[3] The Chinese Academy of Sciences, Science and Technology Progress in China, Available at: /eng2003/page/S&T/PSRT.htm, August 28, 2006
[4] Ministry of Science and Technology of the People´s Republic of China, S&T Statistics Data Book,
Available at: / , July 21, 2006
in computational chemistry ❖ Molecular electronic devices in nano-chemistry ❖ Highly efficient metathesis polymerization
[1] XG Zou, WZ Xia, and WP Liang, A Comparison of Hot Chemical Research Areas in China and Abroad, China Basic Science, 2003, 4, 7-40.
[1] Ci Lijie, Xie Sishen, Tang Dongsheng, Yan Xiaoqin, Li Yubao, Liu Zuqin, Zou Xiaoping, Zhou Weiya, et. al. Controllable growth of single wall carbon nanotubes by pyrolizing acetylene on the floating iron catalysts, Chemical Physics Letters, 2001 ,349,191-195
❖ Template-based growth method invented in CAS can control both the diameter and growth direction of the multi-walled carbon [1]
❖ Yarns made by carbon tubes and woven into a variety of macroscopic objects, such as bulletproof vests and materials that block electromagnetic waves. [1,2]
❖ Superplastic property of nanostructured copper. It can be elongated at RT to more than 50 times its original length without breaking. [1,2,3]
❖ Copper growth twins, a specific type of crystalline microstructure. Tensile strength can be 10 times greater than its conventional counter part, while retaining the conductivity. [1,2,3]
[1] Ping Zhou, Loet Leydesdorff, The Emergence of China as a Leading Nation in Science: /ChinaScience/ChinaScience.pdf
3
Overview of Chinese Chemical research Development
❖ Carbon nanotubes (CNTs): all carbon tubes with diameter comparable to DNA are available in two varieties: single-walled or multi-walled [3,4]
[1] Ministry of Science and Technology of the People´s Republic of China, S&T Statistics Data Book, Available at: / , July 21, 2006
❖ China has become the world's third largest research and development (R&D) performer (behind only the United
States and Japan) [1]
❖ China’s total citation rate has also been on an increase at an exponential rate during the last decade [2,3]
[2] K Jiang, Q Li, S Fan, Spinning continuous carbon nanotube yarns, NATURE, 2002, 419, 801
[3] Lu, Y Shen, X Chen, L Qian, K Lu,Ultrahigh Strength and High Electrical Conductivity in Copper,
❖ Main Progress in Chinese Chemical Research ❖ Main National Research Programs ❖ Online Resources Available for China Chemical
Research
1
Overview of Chinese Chemical research Development
❖ Chinese chemical research has more than tripled since 1989 (statistics from CA) [2,3]
❖ As of 2005, 128 out of 1,000 journal titles are most frequently cited in CA (CA 1000), 920 journal titles were included in CA [2,3,4]
[1] Fact Sheet: Science and Engineering Indicators, 2006: Excerpts, February 23, 2006, /news/news_summ.jsp [2] ISTIC, 2003. 2002年度中国科技论文统计结果 (Statistic results of Chinese science and technology publications in 2002), Beijing. [3] ISTIC, 2004. 2003 年度中国科技论文统计结果 (Statistic results of Chinese science and technology publications in 2003), Beijing