Ketoconazole_DataSheet_MedChemExpress
209种多氯联苯单体编号及中英文对照与CAS号
209种多氯联苯单体PCB序号中文名称CAS 英文名称PCB-001 2-氯联苯2051-60-7 2-Chlorobiphenyl PCB-002 3-氯联苯2051-61-8 3-Chlorobiphenyl PCB-003 4-氯联苯2051-62-9 4-Chlorobiphenyl PCB-004 2,2'-二氯联苯13029-08-8 2,2'-Dichlorobiphenyl PCB-005 2,3-二氯联苯16605-91-7 2,3-Dichlorobiphenyl PCB-006 2,3'-二氯联苯25569-80-6 2,3'-Dichlorobiphenyl PCB-007 2,4-二氯联苯33284-50-3 2,4-Dichlorobiphenyl PCB-008 2,4'-二氯联苯34883-43-7 2,4'-Dichlorobiphenyl PCB-009 2,5-二氯联苯34883-39-1 2,5-Dichlorobiphenyl PCB-010 2,6-二氯联苯33146-45-1 2,6-Dichlorobiphenyl PCB-011 3,3'-二氯联苯2050-67-1 3,3'-Dichlorobiphenyl PCB-012 3,4-二氯联苯2974-92-7 3,4-Dichlorobiphenyl PCB-013 3,4'-二氯联苯2974-90-5 3,4'-Dichlorobiphenyl PCB-014 3,5-二氯联苯34883-41-5 3,5-Dichlorobiphenyl PCB-015 4,4'-二氯联苯2050-68-2 4,4'-Dichlorobiphenyl PCB-016 2,2',3-三氯联苯38444-78-9 2,2',3-Trichlorobiphenyl PCB-017 2,2',4-三氯联苯37680-66-3 2,2',4-Trichlorobiphenyl PCB-018 2,2',5-三氯联苯37680-65-2 2,2',5-Trichlorobiphenyl PCB-019 2,2',6-三氯联苯38444-73-4 2,2',6-Trichlorobiphenyl PCB-020 2,3,3'-三氯联苯38444-84-7 2,3,3'-Trichlorobiphenyl PCB-021 2,3,4-三氯联苯55702-46-0 2,3,4-Trichlorobiphenyl PCB-022 2,3,4'-三氯联苯38444-85-8 2,3,4'-Trichlorobiphenyl PCB-023 2,3,5-三氯联苯55720-44-0 2,3,5-Trichlorobiphenyl PCB-024 2,3,6-三氯联苯55702-45-9 2,3,6-Trichlorobiphenyl PCB-025 2,3',4-三氯联苯55712-37-3 2,3',4-Trichlorobiphenyl PCB-026 2,3',5-三氯联苯38444-81-4 2,3',5-Trichlorobiphenyl PCB-027 2,3',6-三氯联苯38444-76-7 2,3',6-Trichlorobiphenyl PCB-028 2,4,4'-三氯联苯7012-37-5 2,4,4'-Trichlorobiphenyl PCB-029 2,4,5-三氯联苯15862-07-4 2,4,5-Trichlorobiphenyl PCB-030 2,4,6-三氯联苯35693-92-6 2,4,6-Trichlorobiphenyl PCB-031 2,4',5-三氯联苯16606-02-3 2,4',5-Trichlorobiphenyl PCB-032 2,4',6-三氯联苯38444-77-4 2,4',6-Trichlorobiphenyl PCB-033 2',3,4-三氯联苯38444-86-9 2',3,4-Trichlorobiphenyl PCB-034 2',3,5-三氯联苯37680-68-5 2',3,5-Trichlorobiphenyl PCB-035 3,3',4-三氯联苯37680-69-6 3,3',4-Trichlorobiphenyl PCB-036 3,3',5-三氯联苯38444-87-0 3,3',5-Trichlorobiphenyl PCB-037 3,4,4'-三氯联苯38444-90-5 3,4,4'-Trichlorobiphenyl PCB-038 3,4,5-三氯联苯53555-66-1 3,4,5-Trichlorobiphenyl PCB-039 3,4',5-三氯联苯38444-88-1 3,4',5-Trichlorobiphenyl PCB-040 2,2',3,3'-四氯联苯38444-93-8 2,2',3,3'-Tetrachlorobiphenyl PCB-041 2,2',3,4-四氯联苯52663-59-9 2,2',3,4-Tetrachlorobiphenyl PCB-042 2,2',3,4'-四氯联苯36559-22-5 2,2',3,4'-Tetrachlorobiphenyl PCB-043 2,2',3,5-四氯联苯70362-46-8 2,2',3,5-Tetrachlorobiphenyl PCB-044 2,2',3,5'-四氯联苯41464-39-5 2,2',3,5'-Tetrachlorobiphenyl PCB-045 2,2',3,6-四氯联苯70362-45-7 2,2',3,6-Tetrachlorobiphenyl PCB-046 2,2',3,6'-四氯联苯41464-47-5 2,2',3,6'-TetrachlorobiphenylPCB-050 2,2',4,6-四氯联苯62796-65-0 2,2',4,6-Tetrachlorobiphenyl PCB-051 2,2',4,6'-四氯联苯68194-04-7 2,2',4,6'-Tetrachlorobiphenyl PCB-052 2,2',5,5'-四氯联苯35693-99-3 2,2',5,5'-Tetrachlorobiphenyl PCB-053 2,2',5,6'-四氯联苯41464-41-9 2,2',5,6'-Tetrachlorobiphenyl PCB-054 2,2',6,6'-四氯联苯15968-05-5 2,2',6,6'-Tetrachlorobiphenyl PCB-055 2,3,3',4-四氯联苯74338-24-2 2,3,3',4-Tetrachlorobiphenyl PCB-056 2,3,3',4'-四氯联苯41464-43-1 2,3,3',4'-Tetrachlorobiphenyl PCB-057 2,3,3',5-四氯联苯70424-67-8 2,3,3',5-Tetrachlorobiphenyl PCB-058 2,3,3',5'-四氯联苯41464-49-7 2,3,3',5'-Tetrachlorobiphenyl PCB-059 2,3,3',6-四氯联苯74472-33-6 2,3,3',6-Tetrachlorobiphenyl PCB-060 2,3,4,4'-四氯联苯33025-41-1 2,3,4,4'-Tetrachlorobiphenyl PCB-061 2,3,4,5-四氯联苯33284-53-6 2,3,4,5-Tetrachlorobiphenyl PCB-062 2,3,4,6-四氯联苯54230-22-7 2,3,4,6-Tetrachlorobiphenyl PCB-063 2,3,4',5-四氯联苯74472-34-7 2,3,4',5-Tetrachlorobiphenyl PCB-064 2,3,4',6-四氯联苯52663-58-8 2,3,4',6-Tetrachlorobiphenyl PCB-065 2,3,5,6-四氯联苯33284-54-7 2,3,5,6-Tetrachlorobiphenyl PCB-066 2,3',4,4'-四氯联苯32598-10-0 2,3',4,4'-Tetrachlorobiphenyl PCB-067 2,3',4,5-四氯联苯73557-53-8 2,3',4,5-Tetrachlorobiphenyl PCB-068 2,3',4,5'-四氯联苯73575-52-7 2,3',4,5'-Tetrachlorobiphenyl PCB-069 2,3',4,6-四氯联苯60233-24-1 2,3',4,6-Tetrachlorobiphenyl PCB-070 2,3',4',5-四氯联苯32598-11-1 2,3',4',5-Tetrachlorobiphenyl PCB-071 2,3',4',6-四氯联苯41464-46-4 2,3',4',6-Tetrachlorobiphenyl PCB-072 2,3',5,5'-四氯联苯41464-42-0 2,3',5,5'-Tetrachlorobiphenyl PCB-073 2,3',5',6-四氯联苯74338-23-1 2,3',5',6-Tetrachlorobiphenyl PCB-074 2,4,4',5-四氯联苯32690-93-0 2,4,4',5-Tetrachlorobiphenyl PCB-075 2,4,4',6-四氯联苯32598-12-2 2,4,4',6-Tetrachlorobiphenyl PCB-076 2',3,4,5-四氯联苯70362-48-0 2',3,4,5-Tetrachlorobiphenyl PCB-077 3,3',4,4'-四氯联苯32598-13-3 3,3',4,4'-Tetrachlorobiphenyl PCB-078 3,3',4,5-四氯联苯70362-49-1 3,3',4,5-Tetrachlorobiphenyl PCB-079 3,3',4,5'-四氯联苯41464-48-6 3,3',4,5'-Tetrachlorobiphenyl PCB-080 3,3',5,5'-四氯联苯33284-52-5 3,3',5,5'-Tetrachlorobiphenyl PCB-081 3,4,4',5-四氯联苯70362-50-4 3,4,4',5-Tetrachlorobiphenyl PCB-082 2,2',3,3',4-五氯联苯52663-62-4 2,2',3,3',4-Pentachlorobiphenyl PCB-083 2,2',3,3',5-五氯联苯60145-20-2 2,2',3,3',5-Pentachlorobiphenyl PCB-084 2,2',3,3',6-五氯联苯52663-60-2 2,2',3,3',6-Pentachlorobiphenyl PCB-085 2,2',3,4,4'-五氯联苯65510-45-4 2,2',3,4,4'-Pentachlorobiphenyl PCB-086 2,2',3,4,5-五氯联苯55312-69-1 2,2',3,4,5-Pentachlorobiphenyl PCB-087 2,2',3,4,5'-五氯联苯38380-02-8 2,2',3,4,5'-Pentachlorobiphenyl PCB-088 2,2',3,4,6-五氯联苯55215-17-3 2,2',3,4,6-Pentachlorobiphenyl PCB-089 2,2',3,4,6'-五氯联苯73575-57-2 2,2',3,4,6'-Pentachlorobiphenyl PCB-090 2,2',3,4',5-五氯联苯68194-07-0 2,2',3,4',5-Pentachlorobiphenyl PCB-091 2,2',3,4',6-五氯联苯68194-05-8 2,2',3,4',6-Pentachlorobiphenyl PCB-092 2,2',3,5,5'-五氯联苯52663-61-3 2,2',3,5,5'-Pentachlorobiphenyl PCB-093 2,2',3,5,6-五氯联苯73575-56-1 2,2',3,5,6-Pentachlorobiphenyl PCB-094 2,2',3,5,6'-五氯联苯73575-55-0 2,2',3,5,6'-Pentachlorobiphenyl PCB-095 2,2',3,5',6-五氯联苯38379-99-6 2,2',3,5',6-PentachlorobiphenylPCB-099 2,2',4,4',5-五氯联苯38380-01-7 2,2',4,4',5-Pentachlorobiphenyl PCB-100 2,2',4,4',6-五氯联苯39485-83-1 2,2',4,4',6-Pentachlorobiphenyl PCB-101 2,2',4,5,5'-五氯联苯37680-73-2 2,2',4,5,5'-Pentachlorobiphenyl PCB-102 2,2',4,5,6'-五氯联苯68194-06-9 2,2',4,5,6'-Pentachlorobiphenyl PCB-103 2,2',4,5',6-五氯联苯60145-21-3 2,2',4,5',6-Pentachlorobiphenyl PCB-104 2,2',4,6,6'-五氯联苯56558-16-8 2,2',4,6,6'-Pentachlorobiphenyl PCB-105 2,3,3',4,4'-五氯联苯32598-14-4 2,3,3',4,4'-Pentachlorobiphenyl PCB-106 2,3,3',4,5-五氯联苯70424-69-0 2,3,3',4,5-Pentachlorobiphenyl PCB-107 2,3,3',4',5-五氯联苯70424-68-9 2,3,3',4',5-Pentachlorobiphenyl PCB-108 2,3,3',4,5'-五氯联苯70362-41-3 2,3,3',4,5'-Pentachlorobiphenyl PCB-109 2,3,3',4,6-五氯联苯74472-35-8 2,3,3',4,6-Pentachlorobiphenyl PCB-110 2,3,3',4',6-五氯联苯38380-03-9 2,3,3',4',6-Pentachlorobiphenyl PCB-111 2,3,3',5,5'-五氯联苯39635-32-0 2,3,3',5,5'-Pentachlorobiphenyl PCB-112 2,3,3',5,6-五氯联苯74472-36-9 2,3,3',5,6-Pentachlorobiphenyl PCB-113 2,3,3',5',6-五氯联苯68194-10-5 2,3,3',5',6-Pentachlorobiphenyl PCB-114 2,3,4,4',5-五氯联苯74472-37-0 2,3,4,4',5-Pentachlorobiphenyl PCB-115 2,3,4,4',6-五氯联苯74472-38-1 2,3,4,4',6-Pentachlorobiphenyl PCB-116 2,3,4,5,6-五氯联苯18259-05-7 2,3,4,5,6-Pentachlorobiphenyl PCB-117 2,3,4',5,6-五氯联苯68194-11-6 2,3,4',5,6-Pentachlorobiphenyl PCB-118 2,3',4,4',5-五氯联苯31508-00-6 2,3',4,4',5-Pentachlorobiphenyl PCB-119 2,3',4,4',6-五氯联苯56558-17-9 2,3',4,4',6-Pentachlorobiphenyl PCB-120 2,3',4,5,5'-五氯联苯68194-12-7 2,3',4,5,5'-Pentachlorobiphenyl PCB-121 2,3',4,5',6-五氯联苯56558-18-0 2,3',4,5',6-Pentachlorobiphenyl PCB-122 2',3,3',4,5-五氯联苯76842-07-4 2',3,3',4,5-Pentachlorobiphenyl PCB-123 2',3,4,4',5-五氯联苯65510-44-3 2',3,4,4',5-Pentachlorobiphenyl PCB-124 2',3,4,5,5'-五氯联苯70424-70-3 2',3,4,5,5'-Pentachlorobiphenyl PCB-125 2',3,4,5,6'-五氯联苯74472-39-2 2',3,4,5,6'-Pentachlorobiphenyl PCB-126 3,3',4,4',5-五氯联苯57465-28-8 3,3',4,4',5-Pentachlorobiphenyl PCB-127 3,3',4,5,5'-五氯联苯39635-33-1 3,3',4,5,5'-Pentachlorobiphenyl PCB-128 2,2',3,3',4,4'-六氯联苯38380-07-3 2,2',3,3',4,4'-Hexachlorobiphenyl PCB-129 2,2',3,3',4,5-六氯联苯55215-18-4 2,2',3,3',4,5-Hexachlorobiphenyl PCB-130 2,2',3,3',4,5'-六氯联苯52663-66-8 2,2',3,3',4,5'-Hexachlorobiphenyl PCB-131 2,2',3,3',4,6-六氯联苯61798-70-7 2,2',3,3',4,6-Hexachlorobiphenyl PCB-132 2,2',3,3',4,6'-六氯联苯38380-05-1 2,2',3,3',4,6'-Hexachlorobiphenyl PCB-133 2,2',3,3',5,5'-六氯联苯35694-04-3 2,2',3,3',5,5'-Hexachlorobiphenyl PCB-134 2,2',3,3',5,6-六氯联苯52704-70-8 2,2',3,3',5,6-Hexachlorobiphenyl PCB-135 2,2',3,3',5,6'-六氯联苯52744-13-5 2,2',3,3',5,6'-Hexachlorobiphenyl PCB-136 2,2',3,3',6,6'-六氯联苯38411-22-2 2,2',3,3',6,6'-Hexachlorobiphenyl PCB-137 2,2',3,4,4',5-六氯联苯35694-06-5 2,2',3,4,4',5-Hexachlorobiphenyl PCB-138 2,2',3,4,4',5'-六氯联苯35065-28-2 2,2',3,4,4',5'-Hexachlorobiphenyl PCB-139 2,2',3,4,4',6-六氯联苯56030-56-9 2,2',3,4,4',6-Hexachlorobiphenyl PCB-140 2,2',3,4,4',6'-六氯联苯59291-64-4 2,2',3,4,4',6'-Hexachlorobiphenyl PCB-141 2,2',3,4,5,5'-六氯联苯52712-04-6 2,2',3,4,5,5'-Hexachlorobiphenyl PCB-142 2,2',3,4,5,6-六氯联苯41411-61-4 2,2',3,4,5,6-Hexachlorobiphenyl PCB-143 2,2',3,4,5,6'-六氯联苯68194-15-0 2,2',3,4,5,6'-Hexachlorobiphenyl PCB-144 2,2',3,4,5',6-六氯联苯68194-14-9 2,2',3,4,5',6-HexachlorobiphenylPCB-148 2,2',3,4',5,6'-六氯联苯74472-41-6 2,2',3,4',5,6'-Hexachlorobiphenyl PCB-149 2,2',3,4',5',6-六氯联苯38380-04-0 2,2',3,4',5',6-Hexachlorobiphenyl PCB-150 2,2',3,4',6,6'-六氯联苯68194-08-1 2,2',3,4',6,6'-Hexachlorobiphenyl PCB-151 2,2',3,5,5',6-六氯联苯52663-63-5 2,2',3,5,5',6-Hexachlorobiphenyl PCB-152 2,2',3,5,6,6'-六氯联苯68194-09-2 2,2',3,5,6,6'-Hexachlorobiphenyl PCB-153 2,2',4,4',5,5'-六氯联苯35065-27-1 2,2',4,4',5,5'-Hexachlorobiphenyl PCB-154 2,2',4,4',5,6'-六氯联苯60145-22-4 2,2',4,4',5,6'-Hexachlorobiphenyl PCB-155 2,2',4,4',6,6'-六氯联苯33979-03-2 2,2',4,4',6,6'-Hexachlorobiphenyl PCB-156 2,3,3',4,4',5-六氯联苯38380-08-4 2,3,3',4,4',5-Hexachlorobiphenyl PCB-157 2,3,3',4,4',5'-六氯联苯69782-90-7 2,3,3',4,4',5'-Hexachlorobiphenyl PCB-158 2,3,3',4,4',6-六氯联苯74472-42-7 2,3,3',4,4',6-Hexachlorobiphenyl PCB-159 2,3,3',4,5,5'-六氯联苯39635-35-3 2,3,3',4,5,5'-Hexachlorobiphenyl PCB-160 2,3,3',4,5,6-六氯联苯41411-62-5 2,3,3',4,5,6-Hexachlorobiphenyl PCB-161 2,3,3',4,5',6-六氯联苯74474-43-8 2,3,3',4,5',6-Hexachlorobiphenyl PCB-162 2,3,3',4',5,5'-六氯联苯39635-34-2 2,3,3',4',5,5'-Hexachlorobiphenyl PCB-163 2,3,3',4',5,6-六氯联苯74472-44-9 2,3,3',4',5,6-Hexachlorobiphenyl PCB-164 2,3,3',4',5',6-六氯联苯74472-45-0 2,3,3',4',5',6-Hexachlorobiphenyl PCB-165 2,3,3',5,5',6-六氯联苯74472-46-1 2,3,3',5,5',6-Hexachlorobiphenyl PCB-166 2,3,4,4',5,6-六氯联苯41411-63-6 2,3,4,4',5,6-Hexachlorobiphenyl PCB-167 2,3',4,4',5,5'-六氯联苯52663-72-6 2,3',4,4',5,5'-Hexachlorobiphenyl PCB-168 2,3',4,4',5',6-六氯联苯59291-65-5 2,3',4,4',5',6-Hexachlorobiphenyl PCB-169 3,3',4,4',5,5'-六氯联苯32774-16-6 3,3',4,4',5,5'-Hexachlorobiphenyl PCB-170 2,2',3,3',4,4',5-七氯联苯35065-30-6 2,2',3,3',4,4',5-Heptachlorobiphenyl PCB-171 2,2',3,3',4,4',6-七氯联苯52663-71-5 2,2',3,3',4,4',6-Heptachlorobiphenyl PCB-172 2,2',3,3',4,5,5'-七氯联苯52663-74-8 2,2',3,3',4,5,5'-Heptachlorobiphenyl PCB-173 2,2',3,3',4,5,6-七氯联苯68194-16-1 2,2',3,3',4,5,6-Heptachlorobiphenyl PCB-174 2,2',3,3',4,5,6'-七氯联苯38411-25-5 2,2',3,3',4,5,6'-Heptachlorobiphenyl PCB-175 2,2',3,3',4,5',6-七氯联苯40186-70-7 2,2',3,3',4,5',6-Heptachlorobiphenyl PCB-176 2,2',3,3',4,6,6'-七氯联苯52663-65-7 2,2',3,3',4,6,6'-Heptachlorobiphenyl PCB-177 2,2',3,3',4',5,6-七氯联苯52663-70-4 2,2',3,3',4',5,6-Heptachlorobiphenyl PCB-178 2,2',3,3',5,5',6-七氯联苯52663-67-9 2,2',3,3',5,5',6-Heptachlorobiphenyl PCB-179 2,2',3,3',5,6,6'-七氯联苯52663-64-6 2,2',3,3',5,6,6'-Heptachlorobiphenyl PCB-180 2,2',3,4,4',5,5'-七氯联苯35065-29-3 2,2',3,4,4',5,5'-Heptachlorobiphenyl PCB-181 2,2',3,4,4',5,6-七氯联苯74472-47-2 2,2',3,4,4',5,6-Heptachlorobiphenyl PCB-182 2,2',3,4,4',5,6'-七氯联苯60145-23-5 2,2',3,4,4',5,6'-Heptachlorobiphenyl PCB-183 2,2',3,4,4',5',6-七氯联苯52663-69-1 2,2',3,4,4',5',6-Heptachlorobiphenyl PCB-184 2,2',3,4,4',6,6'-七氯联苯74472-48-3 2,2',3,4,4',6,6'-Heptachlorobiphenyl PCB-185 2,2',3,4,5,5',6-七氯联苯52712-05-7 2,2',3,4,5,5',6-Heptachlorobiphenyl PCB-186 2,2',3,4,5,6,6'-七氯联苯74472-49-4 2,2',3,4,5,6,6'-Heptachlorobiphenyl PCB-187 2,2',3,4',5,5',6-七氯联苯52663-68-0 2,2',3,4',5,5',6-Heptachlorobiphenyl PCB-188 2,2',3,4',5,6,6'-七氯联苯74487-85-7 2,2',3,4',5,6,6'-Heptachlorobiphenyl PCB-189 2,3,3',4,4',5,5'-七氯联苯39635-31-9 2,3,3',4,4',5,5'-Heptachlorobiphenyl PCB-190 2,3,3',4,4',5,6-七氯联苯41411-64-7 2,3,3',4,4',5,6-Heptachlorobiphenyl PCB-191 2,3,3',4,4',5',6-七氯联苯74472-50-7 2,3,3',4,4',5',6-Heptachlorobiphenyl PCB-192 2,3,3',4,5,5',6-七氯联苯74472-51-8 2,3,3',4,5,5',6-Heptachlorobiphenyl PCB-193 2,3,3',4',5,5',6-七氯联苯69782-91-8 2,3,3',4',5,5',6-HeptachlorobiphenylPCB-197 2,2',3,3',4,4',6,6'-八氯联苯33091-17-7 2,2',3,3',4,4',6,6'-Octachlorobiphenyl PCB-198 2,2',3,3',4,5,5',6-八氯联苯68194-17-2 2,2',3,3',4,5,5',6-Octachlorobiphenyl PCB-200 2,2',3,3',4,5,6,6'-八氯联苯52663-73-7 2,2',3,3',4,5,6,6'-Octachlorobiphenyl PCB-201 2,2',3,3',4,5',6,6'-八氯联苯40186-71-8 2,2',3,3',4,5',6,6'-Octachlorobiphenyl PCB-199 2,2',3,3',4,5,5',6'-八氯联苯52663-75-9 2,2',3,3',4,5,5',6'-Octachlorobiphenyl PCB-202 2,2',3,3',5,5',6,6'-八氯联苯2136-99-4 2,2',3,3',5,5',6,6'-Octachlorobiphenyl PCB-203 2,2',3,4,4',5,5',6-八氯联苯52663-76-0 2,2',3,4,4',5,5',6-Octachlorobiphenyl PCB-204 2,2',3,4,4',5,6,6'-八氯联苯74472-52-9 2,2',3,4,4',5,6,6'-Octachlorobiphenyl PCB-205 2,3,3',4,4',5,5',6-八氯联苯74472-53-0 2,3,3',4,4',5,5',6-Octachlorobiphenyl PCB-206 2,2',3,3',4,4',5,5',6-九氯联苯40186-72-9 2,2',3,3',4,4',5,5',6-Nonachlorobiphenyl PCB-207 2,2',3,3',4,4',5,6,6'-九氯联苯52663-79-3 2,2',3,3',4,4',5,6,6'-Nonachlorobiphenyl PCB-208 2,2',3,3',4,5,5',6,6'-九氯联苯52663-77-1 2,2',3,3',4,5,5',6,6'-Nonachlorobiphenyl PCB-209 十氯联苯2051-24-3 2,2',3,3',4,4',5,5',6,6'-Decachlorobiphenyl。
Ketoconazole_65277-42-1_DataSheet_MedChemExpress
Product Name:Ketoconazole CAS No.:65277-42-1Cat. No.:HY-B0105Product Data SheetMWt:531.43Formula:C26H28Cl2N4O4Purity :>98%Solubility:DMSO 3 mg/mL; Water <1 mg/mLy Mechanisms:Biological Activity:Ketoconazole is an imidazole anti fungal agent a CYP3A4inhibitor Pathways:Anti-infection; Target:AntifungalKetoconazole is an imidazole anti-fungal agent, a CYP3A4 inhibitor.Target: CYP3A4 Ketoconazole, an imidazole anti-fungal agent, has often produced features of androgen deficiency including decreased libido, gynecomastia, impotence, oligospermia, and decreased testosterone levels, in men being treated for chronic mycotic infections [1]. Ketoconazole also is a cytochromeP450 inhibitor [2].Ketoconazole (KTZ), on the antischistosomal potential of these quinolines against Schistosomamansoni infection by evaluating parasitological, histopathological, and biochemical parameters. Micewere classified into 7 groups: uninfected untreated (I), infected untreated (II), infected treated orallyReferences:[1]. Eil C. Ketoconazole binds to the human androgen receptor. Horm Metab Res. 1992Aug;24(8):367-70.[2]. Seif El-Din SH, et al. Effect of ketoconazole, a cytochrome P450 inhibitor, on the efficacy of g p ()()y with PZQ (1,000 mg/kg) (III), QN (400 mg/kg) (IV), KTZ (10 mg/kg)+QN as group IV (V), HF (400mg/kg) (VI), and KTZ (as group V)+HF (as group VI) (VII). KTZ plus QN or HF produced more i...[]y y quinine and halofantrine against Schistosoma mansoni in mice. Korean J Parasitol. 2013Apr;51(2):165-75.Caution: Not fully tested. For research purposes onlyMedchemexpress LLC18 W i l k i n s o n W a y , P r i n c e t o n , N J 08540,U S AE m a i l : i n f o @m e d c h e m e x p r e s s .c o m W e b : w w w .m e d c h e m e x p r e s s .c o m。
右旋泛醇81-13-0
主要症状和影响，急性和迟发效应
4.3 及时的医疗处理和所需的特殊处理的说明和指示
如必要的话,戴自给式呼吸器去救火。
5 消防措施
5.1 灭火介质
火灾特征 无数据资料 灭火方法及灭火剂 碳氧化物,氮氧化物
5.2 源于此物质或混合物的特别的危害
使用个人防护设备。防止吸入蒸汽、气雾或气体。保证充分的通风。
9 理化特性
9.1 基本的理化特性的信息
a) 外观与性状
形状 : 无数据资料
颜色 : 无数据资料
b) 气味
无数据资料
c) 气味临界值
无数据资料
d) pH值
无数据资料
e) 熔点/凝固点
无数据资料
f) 起始沸点和沸程
118-120℃
g) 闪点
无数据资料
h) 蒸发速率
无数据资料
i) 可燃性(固体,气体) 无数据资料
11.1 毒理学影响的信息
急性毒性 半数致死剂量 (LD50) 经口 - 老鼠 - 15,000 mg/kg 亚 急性毒性 无数据资料 刺激性（总述） 无数据资料 皮肤腐蚀/刺激 皮肤-兔子-轻度的皮肤刺激-4h 严重眼损伤 / 眼刺激 眼睛-兔子-轻度的眼睛刺激 呼吸道或皮肤过敏 如果通过皮肤吸收可能是有害的。可能引起皮肤刺激。 生殖细胞诱变 无数据资料 致癌性 IARC:此产品中没有大于或等于0.1%含量的组分被IARC鉴别为可能的或肯定的人类致癌物。 生殖毒性 生殖 特异性靶器官系统毒性（一次接触） 化学物质毒性作用登记:无数据资料 特异性靶器官系统毒性（反复接触） 无数据资料 潜在的健康影响
化学品安全技术说明书
https://
1 化学品及企业标识
Gelucire-14-44-SDS-MedChemExpress
Inhibitors, Agonists, Screening LibrariesSafety Data Sheet Revision Date:Nov.-23-2018Print Date:Nov.-23-20181. PRODUCT AND COMPANY IDENTIFICATION1.1 Product identifierProduct name :Gelucire 14/44Catalog No. :HY-Y1892CAS No. :121548-04-71.2 Relevant identified uses of the substance or mixture and uses advised againstIdentified uses :Laboratory chemicals, manufacture of substances.1.3 Details of the supplier of the safety data sheetCompany:MedChemExpress USATel:609-228-6898Fax:609-228-5909E-mail:sales@1.4 Emergency telephone numberEmergency Phone #:609-228-68982. HAZARDS IDENTIFICATION2.1 Classification of the substance or mixtureNot a hazardous substance or mixture.2.2 GHS Label elements, including precautionary statementsNot a hazardous substance or mixture.2.3 Other hazardsNone.3. COMPOSITION/INFORMATION ON INGREDIENTS3.1 SubstancesSynonyms:NoneFormula:N/AMolecular Weight:N/ACAS No. :121548-04-74. FIRST AID MEASURES4.1 Description of first aid measuresEye contactRemove any contact lenses, locate eye-wash station, and flush eyes immediately with large amounts of water. Separate eyelids with fingers to ensure adequate flushing. Promptly call a physician.Skin contactRinse skin thoroughly with large amounts of water. Remove contaminated clothing and shoes and call a physician.InhalationImmediately relocate self or casualty to fresh air. If breathing is difficult, give cardiopulmonary resuscitation (CPR). Avoid mouth-to-mouth resuscitation.IngestionWash out mouth with water; Do NOT induce vomiting; call a physician.4.2 Most important symptoms and effects, both acute and delayedThe most important known symptoms and effects are described in the labelling (see section 2.2).4.3 Indication of any immediate medical attention and special treatment neededTreat symptomatically.5. FIRE FIGHTING MEASURES5.1 Extinguishing mediaSuitable extinguishing mediaUse water spray, dry chemical, foam, and carbon dioxide fire extinguisher.5.2 Special hazards arising from the substance or mixtureDuring combustion, may emit irritant fumes.5.3 Advice for firefightersWear self-contained breathing apparatus and protective clothing.6. ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency proceduresUse full personal protective equipment. Avoid breathing vapors, mist, dust or gas. Ensure adequate ventilation. Evacuate personnel to safe areas.Refer to protective measures listed in sections 8.6.2 Environmental precautionsTry to prevent further leakage or spillage. Keep the product away from drains or water courses.6.3 Methods and materials for containment and cleaning upAbsorb solutions with finely-powdered liquid-binding material (diatomite, universal binders); Decontaminate surfaces and equipment by scrubbing with alcohol; Dispose of contaminated material according to Section 13.7. HANDLING AND STORAGE7.1 Precautions for safe handlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.7.2 Conditions for safe storage, including any incompatibilitiesKeep container tightly sealed in cool, well-ventilated area. Keep away from direct sunlight and sources of ignition.Recommended storage temperature:Pure form-20°C 3 years4°C 2 yearsIn solvent-80°C 6 months-20°C 1 monthShipping at room temperature if less than 2 weeks.7.3 Specific end use(s)No data available.8. EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parametersComponents with workplace control parametersThis product contains no substances with occupational exposure limit values.8.2 Exposure controlsEngineering controlsEnsure adequate ventilation. Provide accessible safety shower and eye wash station.Personal protective equipmentEye protection Safety goggles with side-shields.Hand protection Protective gloves.Skin and body protection Impervious clothing.Respiratory protection Suitable respirator.Environmental exposure controls Keep the product away from drains, water courses or the soil. Cleanspillages in a safe way as soon as possible.9. PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical propertiesAppearance White to off-white (Oil)Odor No data availableOdor threshold No data availablepH No data availableMelting/freezing point No data availableBoiling point/range No data availableFlash point No data availableEvaporation rate No data availableFlammability (solid, gas)No data availableUpper/lower flammability or explosive limits No data availableVapor pressure No data availableVapor density No data availableRelative density No data availableWater Solubility No data availablePartition coefficient No data availableAuto-ignition temperature No data availableDecomposition temperature No data availableViscosity No data availableExplosive properties No data availableOxidizing properties No data available9.2 Other safety informationNo data available.10. STABILITY AND REACTIVITY10.1 ReactivityNo data available.10.2 Chemical stabilityStable under recommended storage conditions.10.3 Possibility of hazardous reactionsNo data available.10.4 Conditions to avoidNo data available.10.5 Incompatible materialsStrong acids/alkalis, strong oxidising/reducing agents.10.6 Hazardous decomposition productsUnder fire conditions, may decompose and emit toxic fumes.Other decomposition products - no data available.11.TOXICOLOGICAL INFORMATION11.1 Information on toxicological effectsAcute toxicityClassified based on available data. For more details, see section 2Skin corrosion/irritationClassified based on available data. For more details, see section 2Serious eye damage/irritationClassified based on available data. For more details, see section 2Respiratory or skin sensitizationClassified based on available data. For more details, see section 2Germ cell mutagenicityClassified based on available data. For more details, see section 2CarcinogenicityIARC: No component of this product present at a level equal to or greater than 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.ACGIH: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by ACGIH.NTP: No component of this product present at a level equal to or greater than 0.1% is identified as a anticipated or confirmed carcinogen by NTP.OSHA: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by OSHA.Reproductive toxicityClassified based on available data. For more details, see section 2Specific target organ toxicity - single exposureClassified based on available data. For more details, see section 2Specific target organ toxicity - repeated exposureClassified based on available data. For more details, see section 2Aspiration hazardClassified based on available data. For more details, see section 212. ECOLOGICAL INFORMATION12.1 ToxicityNo data available.12.2 Persistence and degradabilityNo data available.12.3 Bioaccumlative potentialNo data available.12.4 Mobility in soilNo data available.12.5 Results of PBT and vPvB assessmentPBT/vPvB assessment unavailable as chemical safety assessment not required or not conducted.12.6 Other adverse effectsNo data available.13. DISPOSAL CONSIDERATIONS13.1 Waste treatment methodsProductDispose substance in accordance with prevailing country, federal, state and local regulations.Contaminated packagingConduct recycling or disposal in accordance with prevailing country, federal, state and local regulations.14. TRANSPORT INFORMATIONDOT (US)This substance is considered to be non-hazardous for transport.IMDGThis substance is considered to be non-hazardous for transport.IATAThis substance is considered to be non-hazardous for transport.15. REGULATORY INFORMATIONSARA 302 Components:No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.SARA 313 Components:This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.SARA 311/312 Hazards:No SARA Hazards.Massachusetts Right To Know Components:No components are subject to the Massachusetts Right to Know Act.Pennsylvania Right To Know Components:No components are subject to the Pennsylvania Right to Know Act.New Jersey Right To Know Components:No components are subject to the New Jersey Right to Know Act.California Prop. 65 Components:This product does not contain any chemicals known to State of California to cause cancer, birth defects, or anyother reproductive harm.16. OTHER INFORMATIONCopyright 2018 MedChemExpress. The above information is correct to the best of our present knowledge but does not purport to be all inclusive and should be used only as a guide. The product is for research use only and for experienced personnel. It must only be handled by suitably qualified experienced scientists in appropriately equipped and authorized facilities. The burden of safe use of this material rests entirely with the user. MedChemExpress disclaims all liability for any damage resulting from handling or from contact with this product.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: tech@Address: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA。
Calcipotriol_SDS_MedChemExpress
Inhibitors, Agonists, Screening LibrariesSafety Data Sheet Revision Date:Sep.-13-2017Print Date:Sep.-13-20171. PRODUCT AND COMPANY IDENTIFICATION1.1 Product identifierProduct name :CalcipotriolCatalog No. :HY-10001CAS No. :112965-21-61.2 Relevant identified uses of the substance or mixture and uses advised againstIdentified uses :Laboratory chemicals, manufacture of substances.1.3 Details of the supplier of the safety data sheetCompany:MedChemExpress USATel:609-228-6898Fax:609-228-5909E-mail:sales@1.4 Emergency telephone numberEmergency Phone #:609-228-68982. HAZARDS IDENTIFICATION2.1 Classification of the substance or mixtureNot a hazardous substance or mixture.2.2 GHS Label elements, including precautionary statementsNot a hazardous substance or mixture.2.3 Other hazardsNone.3. COMPOSITION/INFORMATION ON INGREDIENTS3.1 SubstancesSynonyms:MC 903; CalcipotrieneFormula:C27H40O3Molecular Weight:412.60CAS No. :112965-21-64. FIRST AID MEASURES4.1 Description of first aid measuresEye contactRemove any contact lenses, locate eye-wash station, and flush eyes immediately with large amounts of water. Separate eyelids with fingers to ensure adequate flushing. Promptly call a physician.Skin contactRinse skin thoroughly with large amounts of water. Remove contaminated clothing and shoes and call a physician.InhalationImmediately relocate self or casualty to fresh air. If breathing is difficult, give cardiopulmonary resuscitation (CPR). Avoid mouth-to-mouth resuscitation.IngestionWash out mouth with water; Do NOT induce vomiting; call a physician.4.2 Most important symptoms and effects, both acute and delayedThe most important known symptoms and effects are described in the labelling (see section 2.2).4.3 Indication of any immediate medical attention and special treatment neededTreat symptomatically.5. FIRE FIGHTING MEASURES5.1 Extinguishing mediaSuitable extinguishing mediaUse water spray, dry chemical, foam, and carbon dioxide fire extinguisher.5.2 Special hazards arising from the substance or mixtureDuring combustion, may emit irritant fumes.5.3 Advice for firefightersWear self-contained breathing apparatus and protective clothing.6. ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency proceduresUse full personal protective equipment. Avoid breathing vapors, mist, dust or gas. Ensure adequate ventilation. Evacuate personnel to safe areas.Refer to protective measures listed in sections 8.6.2 Environmental precautionsTry to prevent further leakage or spillage. Keep the product away from drains or water courses.6.3 Methods and materials for containment and cleaning upAbsorb solutions with finely-powdered liquid-binding material (diatomite, universal binders); Decontaminate surfaces and equipment by scrubbing with alcohol; Dispose of contaminated material according to Section 13.7. HANDLING AND STORAGE7.1 Precautions for safe handlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.7.2 Conditions for safe storage, including any incompatibilitiesKeep container tightly sealed in cool, well-ventilated area. Keep away from direct sunlight and sources of ignition.Recommended storage temperature: 4°C, protect from light, stored under nitrogenShipping at room temperature if less than 2 weeks.7.3 Specific end use(s)No data available.8. EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parametersComponents with workplace control parametersThis product contains no substances with occupational exposure limit values.8.2 Exposure controlsEngineering controlsEnsure adequate ventilation. Provide accessible safety shower and eye wash station.Personal protective equipmentEye protection Safety goggles with side-shields.Hand protection Protective gloves.Skin and body protection Impervious clothing.Respiratory protection Suitable respirator.Environmental exposure controls Keep the product away from drains, water courses or the soil. Cleanspillages in a safe way as soon as possible.9. PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical propertiesAppearance White to off-white (Solid)Odor No data availableOdor threshold No data availablepH No data availableMelting/freezing point No data availableBoiling point/range No data availableFlash point No data availableEvaporation rate No data availableFlammability (solid, gas)No data availableUpper/lower flammability or explosive limits No data availableVapor pressure No data availableVapor density No data availableRelative density No data availableWater Solubility No data availablePartition coefficient No data availableAuto-ignition temperature No data availableDecomposition temperature No data availableViscosity No data availableExplosive properties No data availableOxidizing properties No data available9.2 Other safety informationNo data available.10. STABILITY AND REACTIVITY10.1 ReactivityNo data available.10.2 Chemical stabilityStable under recommended storage conditions.10.3 Possibility of hazardous reactionsNo data available.10.4 Conditions to avoidNo data available.10.5 Incompatible materialsStrong acids/alkalis, strong oxidising/reducing agents.10.6 Hazardous decomposition productsUnder fire conditions, may decompose and emit toxic fumes.Other decomposition products - no data available.11.TOXICOLOGICAL INFORMATION11.1 Information on toxicological effectsAcute toxicityClassified based on available data. For more details, see section 2Skin corrosion/irritationClassified based on available data. For more details, see section 2Serious eye damage/irritationClassified based on available data. For more details, see section 2Respiratory or skin sensitizationClassified based on available data. For more details, see section 2Germ cell mutagenicityClassified based on available data. For more details, see section 2CarcinogenicityIARC: No component of this product present at a level equal to or greater than 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.ACGIH: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by ACGIH.NTP: No component of this product present at a level equal to or greater than 0.1% is identified as a anticipated or confirmed carcinogen by NTP.OSHA: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by OSHA.Reproductive toxicityClassified based on available data. For more details, see section 2Specific target organ toxicity - single exposureClassified based on available data. For more details, see section 2Specific target organ toxicity - repeated exposureClassified based on available data. For more details, see section 2Aspiration hazardClassified based on available data. For more details, see section 212. ECOLOGICAL INFORMATION12.1 ToxicityNo data available.12.2 Persistence and degradabilityNo data available.12.3 Bioaccumlative potentialNo data available.12.4 Mobility in soilNo data available.12.5 Results of PBT and vPvB assessmentPBT/vPvB assessment unavailable as chemical safety assessment not required or not conducted.12.6 Other adverse effectsNo data available.13. DISPOSAL CONSIDERATIONS13.1 Waste treatment methodsProductDispose substance in accordance with prevailing country, federal, state and local regulations.Contaminated packagingConduct recycling or disposal in accordance with prevailing country, federal, state and local regulations.14. TRANSPORT INFORMATIONDOT (US)This substance is considered to be non-hazardous for transport.IMDGThis substance is considered to be non-hazardous for transport.IATAThis substance is considered to be non-hazardous for transport.15. REGULATORY INFORMATIONSARA 302 Components:No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.SARA 313 Components:This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.SARA 311/312 Hazards:No SARA Hazards.Massachusetts Right To Know Components:No components are subject to the Massachusetts Right to Know Act.Pennsylvania Right To Know Components:No components are subject to the Pennsylvania Right to Know Act.New Jersey Right To Know Components:No components are subject to the New Jersey Right to Know Act.California Prop. 65 Components:This product does not contain any chemicals known to State of California to cause cancer, birth defects, or anyother reproductive harm.16. OTHER INFORMATIONCopyright 2017 MedChemExpress. The above information is correct to the best of our present knowledge but does not purport to be all inclusive and should be used only as a guide. The product is for research use only and for experienced personnel. It must only be handled by suitably qualified experienced scientists in appropriately equipped and authorized facilities. The burden of safe use of this material rests entirely with the user. MedChemExpress disclaims all liability for any damage resulting from handling or from contact with this product.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: tech@Address: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA。
泛昔洛韦
密度：1.4g/cm3 熔点：102-104°C 沸 点 ： 5 5 0 . 2 ºC 闪 点 ： 2 8 6 . 6 ºC 折射率：1.628 外观：灰白色粉末 溶解性：易溶于丙酮或甲醇，难溶于乙醇或异丙醇
摩尔折射率：82.66 摩尔体积（cm3/mol）：239.8 等张比容（90.2K）：639.3 表面张力（dyne/cm）：50.4 极化率（10-24cm3）：32.77
进入人体内后迅速转变成喷昔洛韦，喷昔洛韦可被病毒编码的胸苷激酶磷酸化成OCV单磷酸，再经宿主的磷 酸化成为喷昔洛韦三磷酸盐，三磷酸盐在病毒感染的细胞内迅速形成，缓慢代谢，致半衰期延长，参与HBV DNAp的三磷酸鸟苷(Pgtp)竞争，并进入DNA，作用于DNA合成的起始和延伸步骤，抑制DNA的合成，对水痘-带状疱疹 病毒、单纯疱疹病毒1型和2型和HBV均有较强的抑制作用。
泛昔洛韦
药品
目录
01 化合物简介
03 药典信息
02 药品简介 04 安全信息
泛昔洛韦，是一种有机化合物，化学式为C14H19N5O4，是第二代开环核苷类抗病毒药，主要用于疱疹病毒感 染，尤其是带状疱疹。
化合物简介
基本信息 理化性质
分子数据 化学数据
化学式：C14H19N5O4 分子量：321.332 CAS号：-87-4
疏水参数计算参考值（XlogP）：无 氢键供体数量：1 氢键受体数量：8 可旋转化学键数量：9 互变异构体数量：3 拓扑分子极性表面积：122 重原子数量：23 表面电荷：0 复杂度：404 同位素原子数量：0 确定原子立构中心数量：0
药品简介
作用机理
药代动力学
不良反应
泛昔洛韦口服迅速吸收，生物利用度77%，在体内很快转达变为喷昔洛韦，t1/2约为2h，约60-65%经肾排出。 在水痘-带状疱疹病毒感染的细胞内有一个较长的半衰期（9-10小时），单纯疱疹病毒1型和2型感染的细胞内半 衰期分别为10小时和20小时。
德国美剂乐乳糖特殊规格简介
颗粒乳糖Ｔablettose®８0简介一，特点1，Ｔablettose®８0：由一水乳糖粉末经制粒得到的块状颗粒，流动性和可压性良好，适用于直接压片。
2，该规格表面粗糙，比表面积大，有一定的吸附作用，有利于低剂量处方的混合均匀性，减少分层。
3，良好的流动性使其也适用于胶囊填充和散剂，并且经济实惠。
二，理化参数1、粒径分布如下：标准值 典型检测值＜63μm ≤20%； 13%＜180μm 40%－75%； 53%＜400μm ≥85%； 93%＜630μm ≥97% 100%检测仪器为：机械震荡筛2、松密度：0.610 g/l ； 紧密度：0.738 g/l ；卡尔指数：17.3； 休止角: 33；流速：0.786 g/s（埃力克森漏斗３２１，孔径：４／６ｍｍ）。
三，、资质文件具有进口药品注册证。
四，法规符合性符合欧洲药典、美国药典、日本药典、中国药典2010版。
喷雾干燥乳糖FlowLac100简介一、 产品特点由乳糖水溶液喷雾干燥得到的球形颗粒，具有良好的流动性和可压性，表面多孔结构有一点的吸附性能，适用中低剂量片剂直接压片生产工艺。
二、理化参数2、粒径分布如下：标准值典型检测值＜32μm ≤10%；5%＜１00μm2０％－4５％；34%＜2０0μm≥８0％；88%＜25０μm≥9７% 98%检测仪器为：机械震荡筛2、松密度：0.620 g/l ；紧密度：0.710 g/l ；卡尔指数为12.7；休止角：29°；流速：0.867g/s（埃力克森漏斗３２１，孔径：４ｍｍ）。
五、资质文件具有进口药品注册证。
六、法规符合性符合欧洲药典、美国药典、日本药典、中国药典2010版。
乳糖复合物Cellactose®80简介三、产品特点：1，Cellactose®80：是让纤维素充分混悬于乳糖溶液喷干得到的一种一体化（纤维素在球形颗粒中均与分布）的球形颗粒，由75%的α一水乳糖和25%的粉末纤维素组成。
卡洛芬
卡洛芬药物在水-乙腈共溶剂中的荧光光谱摘要药物在水共溶剂中的荧光光谱规律对药物的荧光定量分析有着重要的意义。
本论文研究了苯丙酸类药物卡洛芬在乙睛与水共溶剂中的荧光光谱。
在水共溶剂中不同浓度的卡洛芬溶液的荧光光谱，发现其峰形和峰位不仅随溶剂而变，且随浓度而变。
结果表明随乙睛溶液浓度的增大，荧光激发强度增大并明显蓝移，它在乙腈溶剂中的荧光光谱范围为280~ 480nm。
关键词：卡洛芬；乙腈；荧光光谱1 引言1.1荧光光谱测量简介荧光[1]，是指一种光致发光的冷发光现象。
当某种常温物质经某种波长的入射光（通常是紫外线或X射线）照射，吸收光能后进入激发态，并且立即激发并发出比入射光的波长长的出射光（通常波长在可见光波段）；而且一旦停止入射光，发光现象也随之立即消失。
利用某些物质被紫外光或可见光照射后所产生的荧光，对其进行定性和定量的分析，是当前普遍使用并有发展前途的一种光谱分析技术。
目前，荧光分析方法己成为一种重要且有效的光谱化学分析手段，在众多领域具有重大的应用价值和深远的科学意义。
荧光光谱包括激发谱和发射谱两种。
激发谱是荧光物质在不同波长的激发光作用下测得的某一波长处的荧光强度的变化情况，也就是不同波长的激发光的相对效率；发射谱则是某一固定波长的激发光作用下荧光强度在不同波长处的分布情况，也就是荧光中不同波长的光成分的相对强度。
在辐射能激发出的荧光辐射强度进行定量分析的发射光谱分析方法。
物体经过较短波长的光照，把能量储存起来，然后缓慢放出较长波长的光，放出的这种光就叫荧光。
如果把荧光的能量--波长关系图作出来，那么这个关系图就是荧光光谱。
荧光光谱当然要靠光谱检测才能获得。
高强度激光能够使吸收物种中相当数量的分子提升到激发量子态。
因此极大地提高了荧光光谱的灵敏度。
以激光为光源的荧光光谱适用于超低浓度样品的检测，例如用氮分子激光泵浦的可调染料激光器对荧光素钠的单脉冲检测限已达到10-10摩尔／升，比用普通光源得到的最高灵敏度提高了一个数量级。
OXOID药敏纸片中英文对照
AAmikacin 阿米卡星（丁胺卡那霉素）AK 30µg CT0107B Amoxycillin 阿莫西林（羟氨苄青霉素）AML 2µg CT0060B Amoxycillin 阿莫西林（羟氨苄青霉素）AML 10µg CT0161B Amoxycillin 阿莫西林（羟氨苄青霉素）AML 25µg CT0061BAmoxycillin/clavulanic acid 阿莫西林／克拉维酸（棒酸）（2:1）（澳格门汀）AMC 3µg CT0538BAmoxycillin/clavulanic acid 阿莫西林／克拉维酸（棒酸）（2:1）（澳格门汀）AMC 30µg CT0223BAmpicillin 氨苄西林AMP 2µg CT0002B Ampicillin 氨苄西林AMP 10µg CT0003B Ampicillin 氨苄西林AMP 25µg CT0004B Ampicillin/sulbactam 1:1 氨苄西林/舒巴坦（1:1）SAM 20µg CT0520B Ampicillin/sulbactam 2:1 氨苄西林/舒巴坦（2:1）SAM 30µg CT1653B Apramycin 阿泊拉霉素（安普霉素）APR 15µg CT0545B Azithromycin 阿齐霉素（阿奇霉素）AZM 15µg CT0906B Aztreonam 安曲南ATM 30µg CT0264B BBacitracin 杆菌肽 B 10 units CT0005B CCarbenicillin 羧苄西林（羧苄青霉素）CAR 100µg CT0006B Cefaclor 头孢克洛（头孢克罗）CEC 30µg CT0149B Cefadroxil 头孢羟氨苄CFR 30µg CT0453B Cefamandole 头孢孟多MA 30µg CT0108B Cefepime 头孢吡肟（马斯平）FEP 30µg CT0771B Cefixime 头孢克肟（世福素）CFM 5µg CT0653B Cefoperazone 头孢哌酮（先锋必）CFP 30µg CT0193B Cefoperazone 头孢哌酮（先锋必）CFP 75µg CT0249BCefoperazone/sulbactam 2:1 头孢哌酮／舒巴坦（2：1）（舒普深）SCF 105µg CT1727BCefotaxime 头孢噻肟（凯福隆）CTX 5µg CT0407B Cefotaxime 头孢噻肟（凯福隆）CTX 30µg CT0166B Cefotetan 头孢替坦CTT 30µg CT0665B Cefoxitin 头孢西丁（美福仙）FOX 30µg CT0119B Cefpirome 头孢匹罗CPO 30µg CT1412B Cefpodoxime 头孢泊肟CPD 10µg CT1612B Cefprozil 头孢丙烯CPR 30µg CT1647B Cefsulodin 头孢磺胺（达克舒林）CFS 30µg CT0263B Ceftazidime 头孢他啶CAZ 10µg CT1629B Ceftazidime 头孢他啶CAZ 30µg CT0412B Ceftibuten 头孢布烯CFT 30µg CT1662B Ceftiofur 头孢噻呋EFT 30µg CT1751B Ceftizoxime 头孢唑肟（安保速灵）ZOX 30µg CT0477BCeftriaxone 头孢曲松（头孢三嗪）CRO 30µg CT0417B Cefuroxime sodium 头孢呋新钠CXM 5µg CT0406B Cefuroxime sodium 头孢呋新钠CXM 30µg CT0127B Cephalexin 头孢氨苄（头孢力新，先锋IV）CL 30µg CT0007B Cephalothin 头孢噻吩（头孢菌素，先锋I ）KF 30µg CT0010B Cephazolin 头孢唑啉（先锋V）KZ 30µg CT0011B Cephradine 头孢拉定（先锋VI）CE 30µg CT0063B Chloramphenicol 氯霉素 C 10µg CT0012B Chloramphenicol 氯霉素 C 30µg CT0013B Chloramphenicol 氯霉素 C 50µg CT0014B Cinoxacin 西诺沙星CIN 100µg CT0162B Ciprofloxacin 环丙沙星（悉复欢）CIP 1µg CT0623B Ciprofloxacin 环丙沙星（悉复欢）CIP 5µg CT0425B Ciprofloxacin 环丙沙星（悉复欢）CIP 10µg CT1615B Clarithromycin 克拉霉素CLR 2µg CT1599B Clarithromycin 克拉霉素CLR 5µg CT1623B Clarithromycin 克拉霉素CLR 15µg CT0693BClindamycin 克林霉素（氯林可霉素，氯洁霉素）DA 2µg CT0064BClindamycin 克林霉素（氯林可霉素，氯洁霉素）DA 10µg CT0015BCloxacillin 氯唑西林（邻氯青霉素）OB 5µg CT0016B Colistin sulphate 多粘菌素E（硫酸粘杆菌素）CT 10µg CT0017B Colistin sulphate 多粘菌素E（硫酸粘杆菌素）CT 25µg CT0065B Colistin sulphate 多粘菌素E（硫酸粘杆菌素）CT 50µg CT0664B Compound sulphonamides 磺胺复合物S3 300µg CT0059B 抗生素英文名全称中文名全称名称缩写浓度产品编号DDoxycycline 强力霉素DO 30µg CT0018B EEnrofloxacin 恩诺沙星ENR 5µg CT0639B Ertapenem 厄他培南ETP 10µg CT1761B Erythromycin 红霉素 E 5µg CT0066B Erythromycin 红霉素 E 10µg CT0019B Erythromycin 红霉素 E 15µg CT0020B Erythromycin 红霉素 E 30µg CT0021B抗生素英文名全称中文名全称名称缩写浓度产品编号FFlorfenicol 氟苯尼考FFC 30µg CT1754BFluconazole 氟康唑FCA 25µg CT1806B Flumequine 氟甲喹UB 30µg CT0666B Fosfomycin 磷霉素FOS 50µg CT0183B 抗生素英文名全称中文名全称名称缩写浓度产品编号Framycetin 新霉素B FY 100µg CT0071B Fusidic acid 褐霉素（夫西地酸）FD 5µg CT0493B Fusidic acid 褐霉素（夫西地酸）FD 10µg CT0023B Fusidic acid 褐霉素（夫西地酸）FD 50µg CT1617B GGentamicin 庆大霉素CN 10µg CT0024B Gentamicin 庆大霉素CN 30µg CT0072B Gentamicin 庆大霉素CN 120µg CT0794B Gentamicin 庆大霉素CN 200µg CT0695B IImipenem 亚胺培南（配能）IPM 10µg CT0455B KKanamycin 卡那霉素K 5µg CT0025B Kanamycin 卡那霉素K 30µg CT0026B LLatamoxef 拉氧头孢MOX 30µg CT0302B Levofloxacin 左氧氟沙星（可乐必妥）LEV 1µg CT1586B Levofloxacin 左氧氟沙星（可乐必妥）LEV 5µg CT1587B Lincomycin 林可霉素（洁霉素）MY 2µg CT0027B Lincomycin 林可霉素（洁霉素）MY 10µg CT0123B Lincomycin 林可霉素（洁霉素）MY 15µg CT0028BLincomycin/neomycin 林可霉素（洁霉素）/新霉素LN 75µg CT1757BLincomycin/spectinomycin 林可霉素/壮观霉素LS 109µg CT1758B Linezolid 利奈唑胺LZD 10µg CT1649B Linezolid 利奈唑胺LZD 30µg CT1650B Lomefloxacin 洛美沙星LOM 10µg CT1661B MMecillinam 美西林MEL 10µg CT0096B Mecillinam 美西林MEL 25µg CT0091B Meropenem 美罗培南（美平）MEM 10µg CT0774B Metronidazole 甲硝唑（灭滴灵）MTZ 5µg CT0067B Metronidazole 甲硝唑（灭滴灵）MTZ 50µg CT0466B Mezlocillin 美洛西林MEZ 30µg CT0174B Mezlocillin 美洛西林MEZ 75µg CT0192BMinocycline 米诺环素（二甲胺四环素）MH 30µg CT0030BMoxalactam 拉氧头孢MOX 30µg CT0302B Moxifloxacin 莫西沙星MXF 1µg CT1683B Moxifloxacin 莫西沙星MXF 5µg CT1633BMupirocin 莫匹罗星MUP 5µg CT0522B Mupirocin 莫匹罗星MUP 20µg CT1826B Mupirocin 莫匹罗星MUP 200µg CT0523B NNalidixic acid 萘啶酸NA 30µg CT0031B 抗生素英文名全称中文名全称名称缩写浓度产品编号Neomycin 新霉素N 30µg CT0033BNetilmicin 奈替米星（乙基西梭霉素）NET 10µg CT0424BNetilmicin 奈替米星（乙基西梭霉素）NET 30µg CT0225BNitrofurantoin 呋喃妥因（呋喃妥英） F 50µg CT0069B Nitrofurantoin 呋喃妥因（呋喃妥英） F 100µg CT0034B Nitrofurantoin 呋喃妥因（呋喃妥英） F 200µg CT0035B Nitrofurantoin 呋喃妥因（呋喃妥英） F 300µg CT0036B Norfloxacin 诺氟沙星（氟哌酸）NOR 2µg CT0687B Norfloxacin 诺氟沙星（氟哌酸）NOR 5µg CT0668B Norfloxacin 诺氟沙星（氟哌酸）NOR 10µg CT0434B Novobiocin 新生霉素NV 5µg CT0037B Novobiocin 新生霉素NV 30µg CT0038B Nystatin 制霉菌素NS 100units CT0073B OOfloxacin 氧氟沙星（泰利必妥）OFX 5µg CT0446B Oleandomycin 竹桃霉素OL 15µg CT0039B Oxacillin 苯唑西林OX 1µg CT0159B Oxacillin 苯唑西林OX 5µg CT0040B Oxolinic acid 奥索利酸（恶喹酸）OA 2µg CT0181BOxytetracycline 土霉素（氧四环素，地霉素）OT 30µg CT0041BPPefloxacin 培氟沙星（甲氟哌酸）PEF 5µg CT0661B Penicillin G 青霉素G P 1unit CT0152B Penicillin G 青霉素G P 1.5unit CT0042B Penicillin G 青霉素G P 2units CT0088B Penicillin G 青霉素G P 5units CT0124B Penicllin G 青霉素G P 10units CT0043B Penicillin/novobiocin 青霉素/新生霉素PNV 40 CT1755B Pipemidic acid 吡哌酸PIP 20µg CT0180BPiperacillin 哌拉西林（氧哌嗪青霉素）PRL 30µg CT1619BPiperacillin 哌拉西林（氧哌嗪青霉素）PRL 75µg CT0261BPiperacillin 哌拉西林（氧哌嗪青霉素）PRL 100µg CT0199BPiperacillin/tazobactam 哌拉西林/他唑巴坦（特治星）TZP 36µg CT1616B Piperacillin/tazobactam 哌拉西林/他唑巴坦（特治星）TZP 40µg CT1628B Piperacillin/tazobactam 哌拉西林/他唑巴坦（特治星）TZP 85µg CT0720B Piperacillin/tazobactam 哌拉西林/他唑巴坦（特治星） TZP 110µg CT0725B Pirlimycin 吡利霉素 PIR 2µg CT1668B Polymyxin B多粘菌素BPB300units CT0044BQQuinupristin/dalfopristin 喹奴普汀/达福普汀 QD 15µg CT1644BR抗生素英文名全称 中文名全称 名称缩写 浓度 产品编号 Rifampicin 利福平 RD 2µg CT0078B Rifampicin 利福平 RD 5µg CT0207B Rifampicin 利福平 RD 30µg CT0104BSSpectinomycin 大观霉素（壮观霉素） SH 10µg CT0046B Spectinomycin 大观霉素（壮观霉素） SH 25µg CT0411B Spectinomycin 大观霉素（壮观霉素） SH 100µg CT0823B Spiramycin 螺旋霉素 SP 100µg CT0232B Streptomycin 链霉素 S 10µg CT0047B Streptomycin链霉素 S 25µg CT0048B Sulbactam/ampicillin 1 : 1舒巴坦/氨苄西林 SAM 20µg CT0520BSulbactam/ampicillin 1 : 2 舒巴坦/氨苄西林（优立新） SAM 30µg CT1653B Sulphafurazole 磺胺异恶唑 SF300µg CT0075B Sulphamethoxazole 磺胺甲基异恶唑（新诺明） RL25µg CT0051B Sulphamethoxazole 磺胺甲基异恶唑（新诺明） RL 100µg CT0074B Sulphamethoxazole/trimethoprim 19 : 1 磺胺甲基异恶唑（新诺明）/甲氧苄氨嘧啶 SXT 25µg CT0052B Sulphonamides compound 磺胺复合物 S3 300µg CT0059BT Teicoplanin 替考拉宁（壁霉素） TEC 30µg CT0647B Telithromycin 泰利霉素 TEL 15µg CT1714B Tetracycline 四环素 TE 10µg CT0053B Tetracycline 四环素 TE 30µg CT0054B Ticarcillin 替卡西林（羧噻吩青霉TIC75µgCT0167B素）Ticarcillin/clavulanic acid 7.5 : 1 替卡西林／克拉维酸（7.5:1） TIM 85µg CT0449B Tigecycline 替加环素 TGC 15µg CT1841B Tilmicosin 替米考星 TIL 15µg CT1756B Tobramycin 妥布霉素（托普霉素） TOB 10µg CT0056B Tobramycin 妥布霉素（托普霉素） TOB 30µg CT1618B Trimethoprim 甲氧苄氨嘧啶 W 1.25µg CT0057B Trimethoprim 甲氧苄氨嘧啶 W 2.5µg CT0070B Trimethoprim 甲氧苄氨嘧啶 W 5µg CT0076B Trimethoprim/sulphamethoxazole 1:19 甲氧苄氨嘧啶/磺胺甲基异恶唑（复方新诺明） SXT 25µg CT0052B V Vancomycin 万古霉素（稳可信） VA 5µg CT0188B Vancomycin 万古霉素（稳可信） VA 30µg CT0058B Voriconazole 优立康唑 VOR 1µg CT1807B 注释： CLSI: Clinical ａnd Laboratory Standards Institute 美国临床实验室标准化研究所DIN: Deutsches Institut f ür Normung 德国标准化学会 BSAC: British Society for Antimicrobial Chemotherapy 英国抗生素化疗协会SRGA: Swedish Reference Group for Antibiotics 瑞典抗生素委员会 SFM: Soci ét é Fran çaise de Microbiologie 法国微生物学会注：红色为兽禽用抗生素，绿色为农作物用抗生素，其余为人用抗生素。
Etomoxir_DataSheet_MedChemExpress
Inhibitors, Agonists, Screening Libraries Data SheetBIOLOGICAL ACTIVITY:Etomoxir is a potent inhibitor of carnitine palmitoyltransferase–I (CPT–1).IC50 & Target: CPT–1[1]In Vitro: Etomoxir binds irreversibly to the catalytic site of CPT–1 inhibiting its activity, but also upregulates fatty acid oxidation enzymes. Etomoxir is developed as an inhibitor of the mitochondrial carnitine palmitoyltransferase–1 (CPT–1) located on the outer mitochondrial membrane. Etomoxir, in the liver can act as peroxisomal proliferator, increasing DNA synthesis and liver growth.Thus, etomoxir, in addition of being a CPT1 inhibitor could be considered as a PPARalpha agonist [1]. Etomoxir is a member of the oxirane carboxylic acid carnitine palmitoyl transferase I inhibitors and has been suggested as a therapeutic agent for the treatment of heart failure. Acute Etomoxir treatment irreversibly inhibits the activity of carnitine palmitoyltransferase I. As a result, fatty acid import into the mitochondria and β–oxidation is reduced, whereas cytosolic fatty acid accumulates and glucose oxidation is elevated. Prolonged incubation (24 h) with Etomoxir produces diverse effects on the expression of several metabolic enzyme [2].In Vivo: Etomoxir is an inhibitor of free fatty acid (FFA) oxidation–related key enzyme CPT1. P53 interacts directly with Bax, which is inhibited by Etomoxir, further confirming the direct interaction of P53 and Bax, and the involvement of FAO–mediatedmitochondrial ROS generation in db/db mice [3]. Rats are injected daily with Etomoxir, a specific CPT–I inhibitor, for 8 days at 20mg/kg of body mass. Etomoxir–treated rats display a 44% reduced cardiac CPT–I activity. The treatment of Lewis rats for 8 days with 20 mg/kg Etomoxir does not alter blood glucose, which is in line with comparable etomoxir–feeding studies. Similarly, Etomoxir feeding does not affect general growth characteristics such as gain in body mass, nor does it affect hindlimb muscle mass.However, heart mass and liver mass are both significantly increased by 11% in Etomoxir–treated rats [4].PROTOCOL (Extracted from published papers and Only for reference)Cell Assay: Etomoxir is dissolved in DMSO and stored, and then diluted with appropriate medium before use [2]. [2]Rat heart H9c2 myoblastic cells are incubated in DMEM containing 10% fetal bovine serum until near confluence. In some experiments,cells are preincubated for 2 h with DMEM (serum–free) in the absence or presence of 1–80 μM Etomoxir and then incubated for 2 h with 0.1 mM [1–14C]oleic acid (10 μCi/dish, binds to BSA in a 1:1 molar ratio). In other experiments, cells arepreincubated for 2 h plus or minus 40 μM Etomoxir and then incubated for 2 h with 0.1 μM or 0.1 mM [1,3–3H]glycerol (10μCi/dish), 0.1 mM [1–14C]oleic acid (2 μCi/dish, binds to BSA in a 1:1 molar ratio), 0.1 mM [1–14C]palmitic acid (2μCi/dish, binds to BSA in a 1:1 molar ratio), 28 μM [3H]ethanolamine (2 μCi/dish), 28 μM [methyl–3H]choline (2 μCi/dish), 0.4mM [3H]serine (20 μCi/dish), or 40 μM myo–[3H]inositol (10 μCi/dish). The medium is removed and the cells washed twice withice–cold saline and then harvested from the dish with 2 mL methanol–water (1:1, v/v) for lipid extraction. An aliquot of thehomogenate is taken for the determination of total uptake of radioactivity into cells. Phospholipids are then isolated andradioactivity in these determined [2].Animal Administration: Etomoxir is dissolved in 0.9% (w/v) NaCl (Rat)[4].[3][4]Mice [3]Product Name:Etomoxir Cat. No.:HY-50202CAS No.:124083-20-1Molecular Formula:C 17H 23ClO 4Molecular Weight:326.82Target:Others Pathway:Others Solubility:10 mM in DMSO80 male C57BLKS/J lar–Lepr db/db mice and 20 wild type littermates (8 week) are used. db/db mice are randomly divided into four groups: db/db group, Etomoxir group, MitoQ group, and PFT–α group. In the Etomoxir group, mice are intraperitoneally injected with 1 mg/kg Etomoxir twice every week. In the MitoQ group, 50 μM MitoQ is given to the mice in water. Water bottles, containing either MitoQ, are covered with aluminum foil, and all bottles are refilled every 3 days. In the PFT–α group, mice are intraperitoneally injected with 1 mg/kg PFT–α twice every week. WT mice are administrated with vehicle instead. The experimental period is 8 weeks. At the end, peripheral blood samples and bone marrow cells are harvested for the assays.Rat[4]Male Lewis rats, weighing 150–200 g, are used in the present study. Animals are kept on a 12 h:12 h light/dark cycle and fed a Purina Chow diet and water ad libitum. The rats are divided into two groups: (1) control and (2) Etomoxir. Etomoxir (20 mg/kg of body weight) is dissolved in 0.9% (w/v) NaCl and administered intraperitoneally for 8 days. Control rats receive saline. The last injection is given 24 h before the experiment. Animals are anaesthetized with an intraperitoneal injection of a nembutal and heparin (3:1) mixture. Subsequently, the heart is removed for LCFA uptake studies and for analyses of transporter protein contents.References:[1]. Rupp H, et al. The use of partial fatty acid oxidation inhibitors for metabolic therapy of angina pectoris and heart failure. Herz. 2002 Nov;27(7):621–36.[2]. Xu FY, et al. Etomoxir mediates differential metabolic channeling of fatty acid and glycerol precursors into cardiolipin in H9c2 cells. J Lipid Res. 2003 Feb; 44(2):415–23.[3]. Li J, et al. FFA–ROS–P53–mediated mitochondrial apoptosis contributes to reduction of osteoblastogenesis and bone mass in type 2 diabetes mellitus. Sci Rep. 2015 Jul 31;5:12724.[4]. Luiken JJ, et al. Etomoxir–induced partial carnitine palmitoyltransferase–I (CPT–I) inhibition in vivo does not alter cardiac long–chain fatty acid uptake and oxidation rates. Biochem J. 2009 Apr 15;419(2):447–55.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: tech@Address: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA。
[宝典]对乙酰氨基酚
![[宝典]对乙酰氨基酚](https://img.taocdn.com/s3/m/a834f836dc36a32d7375a417866fb84ae45cc3f3.png)
【对乙酰氨基酚】
结构式：
日文名：アセトアミノフェン
英文名：Acetaminophen
或Paracetamol
解离常数（25℃）：pKa = 9.5（针对苯酚基团上的羟基）
在各溶出介质中的溶解度（37℃）：pH1.2：14.9mg/ml pH4.0：15.3mg/ml
pH 6.8：15.4mg/ml 水：15.8mg/ml
在各溶出介质中的稳定性：
水：未测定。
在各pH值溶出介质中：未测定。
光：未测定。
《四条标准溶出曲线》
溶出度试验条件：桨板法/50转、溶出介质中不添加表面活性剂。
< 1g:200mg规格颗粒剂>
< 200mg规格片剂>
《质量标准》
取本品1包（或1片），照溶出度测定法（桨板法），以水900ml为溶剂，转速为每分钟50转，依法操作，经30分钟（片剂15分钟）时，取溶液适量，弃去至少10ml初滤液，精密量取续滤液3ml，置100ml量瓶中，加水稀释至刻度，摇匀，作为供试品溶液。
另精密称取经105℃干燥2小时的对照品15mg，置100ml量瓶中，加甲醇2ml使溶解，再加水稀释至刻度，摇匀，精密量取1ml，置25ml量瓶中，加水稀释至刻度，摇匀，作为对照品溶液。
取上述两种溶液照紫外-可见分光光度法，在243nm的波长处测定吸光度，计算出每包（片）溶出量，限度为标示量的80%，应符合规定。
泮托拉唑钠的相关中间体
结构式：
产品名称：5-(二氟甲氧基)-2-{[(4-氯-3-甲氧基-2-吡4-Chloro-3-methoxy-2-pyridinyl)methy l]thio-1 H-benz im idazo le [CAS]：[368890-20-4] 结构式：
结构式：
产品名称：5-(二氟甲氧基)-2-{[(3,4-二甲氧基-2-吡啶基)甲基]硫}-1H-苯并咪唑 5-Difluoromethoxy-2-[(3,4-dimethoxy-2-pyridinyl)methy l]thio-1 H-benz im idazo le [CAS]：[102625-64-9]
产品名称：4-氯-3-甲氧基-2-甲基吡啶 N-氧化物 4-Chloro-3-methoxy-2-methylpyridine N-oxide [CAS]：[122307-41-9] 结构式：
产品名称：2-羟甲基-3,4-二甲氧基吡啶 2-Hydroxymethyl-3,4-dimethoxypyr id ine [CAS]：[72830-08-1] 结构式：
中文名:4-二氟甲氧基苯胺 4-difluoromethoxyaniline CAS:[22236-10-8 ] 分子式:C7 H7F2NO 分子量:159.133 结构式：
中文名:3-二氟甲氧基苯胺 3-Difluoromethoxy aniline CAS :[22236-08-4] 结构式：
产品名称： 4-氯-3-甲氧基-2-氯甲基吡啶盐酸盐 4-Chloro-2-chloromethyl-3-methoxypyridine,Hydrochloride Salt 结构式：
产品名称： 4-二氟甲氧基-乙酰苯胺 4-Difluoromethoxy-acetanilid N-(4-二氟甲氧基苯基)-乙酰胺 N-(4-Difluoromethoxyphenyl)acetamide
CAS号22071-15-4_Ketoprofen_相关资料MedBio
3,4-dihydro Naratriptan
3,4-dihydro Naratriptan
12167
货号
中文名称
英文名称
CAS
包装
纯度
MedBio
MED16938
W-84 dibromide
W-84 dibromide
21093-51-6
10mg
≥98%
106469-57-2
50mg
≥98%
品牌
货号
中文名称
英文名称
CAS
包装
纯度
MedBio
MED16742
Pancuronium dibromide
Pancuronium dibromide
15500-66-0
10mM (in 1mL DMSO)
≥98%
品牌
货号
中文名称
英文名称
CAS
包装
纯度
MedBio
品牌
货号
中文名称
英文名称
CAS
包装
纯度
MedBio
MED17059
Paroxetine maleate
Paroxetine maleate
64006-44-6
10mg
≥98%
品牌
货号
中文名称
英文名称
CAS
包装
纯度
MedBio
MED16517
alpha-Endorphin
alpha-Endorphin
体内研究
酮洛芬（0.32-10 mg / kg，sc）剂量依赖性地抑制酸诱导的嵌套抑制（IC50,2.05 mg / kg），并以0.1-10 mg / kg逆转CFA诱导的这种抑郁症，IC50为0.18小鼠中的mg / kg [2]。
毒毛旋花苷K安全技术说明书MSDS
化学品安全技术说明书第一部分化学品及企业标识化学品中文名：毒毛旋花苷 K化学品英文名：strophantin-K化学品别名：-CAS No.：11005-63-3EC No.：234-239-9分子式：C36H54O14产品推荐用途：请咨询生产商。
产品限制用途：请咨询生产商。
第二部分危险性概述| 紧急情况概述固体。
吞食后有毒。
吸入有毒。
长期暴露有损伤健康的危险。
| GHS 危险性类别根据 GB 30000-2013 化学品分类和标签规范系列标准（参阅第十六部分），该产品分类如下：急毒性-口服，类别 3；急毒性-吸入，类别 3；特定目标器官毒性-重复接触，类别 2。
| 标签要素象形图警示词：危险危险信息：吞咽会中毒，吸入会中毒，长期或重复接触可能对器官造成伤害。
防范说明预防措施：不要吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
作业后彻底清洗。
使用本产品时不要进食、饮水或吸烟。
只能在室外或通风良好之处使用。
事故响应：呼叫中毒急救中心/医生。
如感觉不适，须求医/就诊。
漱口。
如误吞咽：立即呼叫中毒急救中心/医生。
如误吸入：将受人转移到空气新鲜处，保持呼吸舒适的体位。
安全储存：存放处须加锁。
存放在通风良好的地方。
保持容器密闭。
废弃处置：按照地方/区域/国家/国际规章处置内装物/容器。
| 危害描述物理化学危险无资料健康危害吸入本品在正常生产过程中生成的粉尘可对身体产生毒害作用。
吸入该物质可能会引起对健康有害的影响或呼吸道不适。
意外食入本品可能引起毒害作用。
意外食入本品可能对个体健康有害。
通过割伤、擦伤或病变处进入血液，可能产生全身损伤的有害作用。
眼睛直接接触本品可导致暂时不适。
环境危害请参阅 SDS 第十二部分。
第三部分成分/组成信息第四部分急救措施| 急救措施描述一般性建议：急救措施通常是需要的，请将本 SDS 出示给到达现场的医生。
皮肤接触：立即脱去污染的衣物。
用大量肥皂水和清水冲洗皮肤。
如有不适，就医。
眼睛接触：用大量水彻底冲洗至少 15 分钟。
尤特奇手册
季胺基甲基丙烯酸酯共
*尤特奇RL 100
丙烯酸乙酯、甲基丙烯酸甲酯和甲基丙烯 聚物A型
Ammonio Methacrylate Copolymer，
□尤特奇RL PO 酸氯化三甲胺基乙酯(1:2:0.2)共聚物
Type A
□尤特奇RL 30D
*尤特奇RS 100 *尤特奇RS PO
季胺基甲基丙烯酸酯共
商品名
化学组成
注册名称
USP/NF
*尤特奇E 100 尤特奇E PO
甲基丙烯酸氨烷基酯共 甲基丙烯酸丁酯、甲基丙烯酸二甲胺基乙
聚物E型 酯和甲基丙烯酸甲酯(1:2:1)共聚物
*尤特奇L 100-55
甲基丙烯酸共聚物C型 Methacrylic Acid Copolymer， Type C
甲基丙烯酸和丙烯酸乙酯(1:1)共聚物 *尤特奇L 30D-55
x两头的圆角y两侧的顶面z侧边a表面积d直径r半径ch曲面高度b侧边高度h总高度wr曲率半径bw周长基本信息eudragit尤特奇l30d55水分散体包衣液的配制eudragit尤特奇l10055配制成水分散体的操作eudragit尤特奇l10055的有机溶液eudragit尤特奇l100和s100的有机溶液应用示例eudragit尤特奇l30d55用于奥美拉唑小丸的肠溶包衣eudragit尤特奇l30d55用于乙酰水杨酸的肠溶包衣eudragit尤特奇l30d55用于硬胶囊的肠溶包衣eudragit尤特奇l10055用于阿司匹林片剂的肠溶包衣eudragit尤特奇l10055用于氨基酸片剂的肠溶包衣eudragit尤特奇l100和s100用于片剂的肠溶包衣eudragit尤特奇l100和s100用于片剂的着色肠溶包衣eudragit尤特奇s100用于便塞停片剂的肠溶包衣肠溶包衣技术1概述许多制剂因药物性质而带有刺激性也有些制剂因胃液或酶的作用会遭失效
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Inhibitors, Agonists, Screening Libraries
Data Sheet
BIOLOGICAL ACTIVITY:
Ketoconazole is an imidazole anti–fungal agent, a CYP3A4 and CYP24A1 inhibitor.
Target: CYP3A4 CYP24A1
Ketoconazole, an imidazole anti–fungal agent, has often produced features of androgen deficiency including decreased libido,gynecomastia, impotence, oligospermia, and decreased testosterone levels, in men being treated for chronic mycotic infections [1].Ketoconazole also is a cytochrome P450 inhibitor [2].
Ketoconazole (KTZ), on the antischistosomal potential of these quinolines against Schistosoma mansoni infection by evaluating parasitological, histopathological, and biochemical parameters. Mice were classified into 7 groups: uninfected untreated (I), infected untreated (II), infected treated orally with PZQ (1,000 mg/kg) (III), QN (400 mg/kg) (IV), KTZ (10 mg/kg)+QN as group IV (V), HF (400mg/kg) (VI), and KTZ (as group V)+HF (as group VI) (VII). KTZ plus QN or HF produced more inhibition (P<0.05) in hepatic CYP450(85.7% and 83.8%) and CYT b5 (75.5% and 73.5%) activities, respectively, than in groups treated with QN or HF alone. This was accompanied with more reduction in female (89.0% and 79.3%), total worms (81.4% and 70.3%), and eggs burden (hepatic; 83.8%,66.0% and intestinal; 68%, 64.5%), respectively, and encountering the granulomatous reaction to parasite eggs trapped in the liver.[3]CYP24A1 inhibitor enhances antiproliferative effects, increases systemic calcitriol exposure, and promotes the activation of caspase–independent apoptosis pathway.[4]
References:
[1]. Seif El–Din SH, et al. Effect of ketoconazole, a cytochrome P450 inhibitor, on the efficacy of quinine and halofantrine against Schistosoma mansoni in mice. Korean J Parasitol. 2013 Apr;51(2):165–75.
[2]. Eil C. Ketoconazole binds to the human androgen receptor. Horm Metab Res. 1992 Aug;24(8):367–70.
[3]. Muindi JR et al. CYP24A1 inhibition enhances the antitumor activity of calcitriol. Endocrinology. 2010 Sep;151(9):4301–12.
Product Name:
Ketoconazole Cat. No.:
HY-B0105CAS No.:
65277-42-1Molecular Formula:
C 26H 28Cl 2N 4O 4Molecular Weight:
531.43Target:
Fungal; Cytochrome P450Pathway:
Anti–infection; Metabolic Enzyme/Protease Solubility:
DMSO: ≥ 5.3 mg/mL
Caution: Product has not been fully validated for medical applications. For research use only.
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