Study of the Reactions $B to D^ pi pi$ and $B to D^ rho pi$

合集下载

Study on the Properties of the Ionosphere

Study on the Properties of the Ionosphere

Study on the Properties of theIonosphereIntroductionThe ionosphere is a region of the Earth's atmosphere that contains ionized gases, mainly oxygen and nitrogen. This region extends from about 60 to 1,000 kilometers above the Earth's surface. The ionosphere plays an important role in the communication, navigation and study of space weather phenomena. In this article, we will discuss the properties of the ionosphere, including its composition, structure and dynamics.Composition of the IonosphereThe composition of the ionosphere varies with altitude. At lower altitudes, the ionosphere is dominated by atomic and molecular oxygen (O and O2), while at higher altitudes, ionized nitrogen (N+) and molecular nitrogen (N2) become more prevalent. The ionization of these gases is caused by solar radiation, which strips electrons from the atoms and molecules in the upper atmosphere.The ionosphere is also known for its layers, which are distinguished by their electron density profiles. The lowest layer is called the D-layer, located at about 60 to 90 kilometers above the Earth's surface. This layer is densest during the day due to ionization by ultraviolet radiation from the Sun. At night, the D-layer becomes less dense due to recombination.Above the D-layer is the E-layer, located at about 90 to 120 kilometers above the Earth's surface. This layer is most active during the day and is responsible for reflecting radio waves with frequencies between 1 and 10 MHz.The F-layer is the highest layer of the ionosphere, located at about 200 to 1,000 kilometers above the Earth's surface. This layer is further divided into the F1 and F2 layers, with the F2 layer being the most important for communication purposes. The F2 layer is responsible for reflecting radio waves with frequencies between 3 and 30 MHz.Structure and Dynamics of the IonosphereThe structure of the ionosphere is influenced by a variety of factors, including solar radiation, geomagnetic activity and wind patterns. These factors can cause variations in the electron density, which can in turn affect communication and navigation systems.For example, during times of high solar activity, the ionosphere can become more ionized, leading to increased absorption of radio waves and disruption of communication and navigation systems. Similarly, geomagnetic storms can cause the ionosphere to change its shape, making it more difficult for signals to pass through.Wind patterns can also affect the ionosphere by causing variations in temperature and pressure. These variations can lead to changes in electron density and can cause the formation of structures such as plasma bubbles, which can interfere with satellite communication.ConclusionThe ionosphere is a complex region of the Earth's atmosphere that plays an important role in communication, navigation and the study of space weather phenomena. Its composition, structure and dynamics are influenced by a variety of factors, including solar radiation, geomagnetic activity and wind patterns. Understanding the properties of the ionosphere is crucial for the development and operation of communication and navigation systems, and for the study of the Earth's upper atmosphere.。

TDQDN

TDQDN
0.4 v=0, j=0 (J=0) X 0.3 VIII VII VI 0.2 V IX
Reaction Probability
0.1 III I 0 2.1 2.2 II 2.3
IV
2.4
2.5
2.7 2.8 2.6 Total Energy (eV)
2.9
3
3.1
3.2
Quasibound States and Resonance Peaks
g
F. Huarte-Larraňaga and U. Manthe, J. Chem. Phys. 113, 5115 (2000); J. Chem. Phys. 116, 2863 (2002). T. Wu, H.J. Werner, and U. Manthe, Science, 306, 227, (2004).
F.Z. London, Elektrochem. 35, 532 (1929); H. Eyring and M.Z. Polani, Phys. Chem. (Munich), B12, 279 (1931). Schatz and A. Kupermann, J. Chem. Phys. 65, 4642 (1976). c. D.H. Zhang and J.Z.H. Zhang, J. Chem. Phys. 101, 1146 (1994); D.Neuhauser, J. Chem. Phys. 100, 9272, (1994). d. D. Wang, J. Chem. Phys. 124, 201105, (2006).
First 9DOF quantum dynamics calculation for a diatom-triatom reaction system in 2006d During the past two decades, quantum dynamics methods well developed for small reaction systems

有关化学的四级英语作文题目

有关化学的四级英语作文题目

有关化学的四级英语作文题目Diving into the world of chemistry is like unlocking a Pandora's box of wonders, where elements dance in a symphony of reactions, creating the very fabric of our reality. The subject of chemistry is not just a field of study; it's a journey through the microscopic universe that governs the macroscopic world we live in. From the air we breathe to the food we eat, chemistry is omnipresent, shaping our lives in ways both subtle and profound.In the realm of English language proficiency, the ability to articulate complex chemical concepts in a clear and engaging manner is a skill that can set one apart in the academic and professional arenas. A well-crafted essay on chemistry not only demonstrates a deep understanding of the subject but also showcases the writer's command of the English language. It's an opportunity to explore theintricate dance of molecules, the transformative power of chemical reactions, and the potential of chemistry to address some of the world's most pressing issues, such as climate change, renewable energy, and healthcare.Writing about chemistry in English requires a delicate balance of technical accuracy and narrative flair. It's about bringing the invisible to life, making the abstract tangible, and illuminating the significance of chemical processes in everyday life. Whether discussing the latest breakthroughs in nanotechnology or the historical milestones that have shapedthe field, the essay should be a testament to the beauty and utility of chemistry.Moreover, a compelling chemistry essay in English should not only inform but also inspire. It should ignite curiosity, provoke thought, and perhaps even change perspectives on the role of chemistry in society. The writer must be adept at weaving a narrative that is both informative and captivating, using language that is precise yet accessible, technical yet engaging.In essence, crafting an essay on chemistry in English is an exercise in translation—not just of language, but of ideas. It's about translating the complex language of atoms and molecules into the universal language of understanding and appreciation. It's a challenge that, when met, can reveal the true essence of chemistry: a subject that is as fundamental to our existence as it is fascinating to explore.。

片仔癀新英文版产品说明书(1-16)

片仔癀新英文版产品说明书(1-16)

英文版产品说明书片仔癀Pien Tze Huang[Medicine name]Proprietary name: Pien Tze HuangChinese pronunciation:Pianzaihuang[Ingredients] Calculus Bovis, Moschus, Radix Notoginsing, Snake’s gall,etc. [Description]It’s an oblate-like mass, with an oblate circle on the surface. The surface is brownish-yellow or greyish-brown, with thin serried striation and mould speckles. Texture is hard, uneasily broken. Section is slightly rough, with even brown color and a small amount of mycelia occasionally. Powder is brownish-yellow or thin brownish-yellow. It smells a bit fragrant and tastes bitter and a bit sweet.[Main functions and actions] Relieving internal heat and deleting toxin, cooling blood and reducing stasis, relieving swelling and stopping pain. Used for treating acute, chronic or viral hepatitis resulting from internal heat or blood stasis, ulcer and pyogenic infections, unknown galls, injuries from falls, fractures, contusions and strains as well as all kinds of inflammations. [Specification] 3 grams per piece[Usage and Dosage]Orally, 0.6 grams a time. for children aged under 8 ,take 0.15-0.3 gram each time. To be taken 2-3 times a day. For external use, grind into powder and mixed it unfiformity with boiled water or vinegar , take suitable quantity and apply to the affected part for several times one day ,keep wetness. or adhere to the instructions of the physician.[Adverse Reactions] Not known[Points for attention] Not to be applied by pregnant women[Precautions] Not known[Storage] Preserve in tightly closed containers, protected from moisture. [Packing]Aluminium and plastic composite- film,3 grams×1 piece/box[Period of Validity] Five years[Approval number] State medical permitment number. Z35020243 [Manufactured] By Zhangzhou Pien Tze Huang Pharmaceutical co ., Ltd.片仔癀胶囊Pien Tze Huang Capsule[Medicine Name]Proprietary name : Pien Tze Huang CapsuleChines pronunciation:Pianzaihuang Jiaonang[Ingredients] Pien Tze Huang[Description]Capsule containing brownish-yellow grain and powder. It smells fragrant and tastes bitter and a bit sweet.[Main functions and actions]Clearing away heat and toxic materials, relieving inflammation and arresting pain, promoting blood circulation to dispel blood stasis. Used in virus hepatitis, boils, inflammatory process of tissue of unknown origin, injury and kinds of inflammatory lesions.[Specification] 0.3 gram per capsule[Usage and Dosage] Orally, 2 pieces a time, one piece a time for children aged 1-5, 3 times a day or under doctor advice[Adverse Reactions] Not known[Points for attention] Not to be applied by pregnant women[Precautions] Not known[Storage] Preserve in tightly closed containers[Packing]Aluminium and plastic packing ,0.3 gram×6 pieces /box[Period of Validity] Three years[Approval number] State medical permitment number. Z35020242. [Manufactured] By Zhangzhou Pien Tze Huang Pharmaceutical co ., Ltd.茵胆平肝胶囊Yindan Pinggan Capsule[Medicine name]Proprietary name: Yindan Pinggan CapsuleChinese pronunciation:Yindan Pinggan Jiaonang[Ingredients] Herba Aryemisiae Scopariae,Radix Gentianae, Pulvis Fellis Suis, Fructus Gardeniae,Radix Scutellariae,Radix Angelicae Sinensis,Radix Paeoniae Alba, Radix Glycyrrhizae[Description] Capsule containing brownish-yellow grain .It tastes very bitter [Functions]Relieving internal heat and deleting moisture, It has significant effectiveness for acute jaundice hepatitis and chronic hepatitis.[Specification] 0.5 gram per capsule[Usage and Dosage] Orally, 2 capsules a time, 3 times a day .[Adverse Reactions] Not known[Contraindications]This medicine is not for the patient whose gallbladder vessel was choked completely .[Precautions] Not known[Storage] Preserve in tightly closed containers, protected from moisture, stored in a cool place.[ Packing]Aluminium and plastic composite packing,0.5 gram×10 pieces×2 sheets /box or medicine plastic bottle , 0.5 gram×36 pieces /bottle[Period of Validity] Three years[Approval number] State medical permitment number. Z35020240 [Manufactured] By Zhangzhou Pien Tze Huang Pharmaceutical co ., Ltd.复方片仔癀软膏说明书Unguentum Pien Tze Huang compositum OintmentPlease read the instruction carefully and use it according to the direction or buy and use it under chemist’s suggestion.[Medicine name]Proprietary name: Unguentum Pien Tze Huang compositum OintmentChinese pronunciation:Fufang Pianzaihuang Ruangao[Ingredients] The power of Pien Tze Huang ,Antivenom tablet[Description] Light brown-yellow ointment, it has special oleaginous taste.[Main action] Relieving internal heat, deleting toxin and stopping pain. Used for viral or bacillary skin disease, such as zosters, herpes simplex, impetigo, folliculitis and acne etc.[Specification] 10 gram per tube/box .[Usage and Dosage]External use only,daub on the affected part,2~3 times daily. [Adverse Reactions] Not known[Contraindications] Not known[Precautions]1.Smoke,alcohol,piguancy and fat food are forbidden.2.Pregnant women should use with caution.3.This medicine is for external use only ant it should not be taken orally.4.Stop using if part anaphylactoid reaction such as rash occur after used this medicine.5. Go to see a doctor if toxic heat strictness with chill fever happens.6.Don’t stave or extrusion when part pathological changes occur.7.It should not be used for patients who have anaphylatoid reaction with this medicine, and irritability corporeity should used with caution.8.It should not be used when the character of this medicine has changed.9.Children administere under the supervision by adults.10.It should be kept out of reach of children.11.If in process of using other medicine, please consult with a physician or chemist before use this medicine.[Medicine reaction] If used other medicines at the same time, the medicine reaction may occur, please consult with physician or chemist the correlative detail. [Storage] Preserve in tightly closed containers, stored in a cool and dry place [Packing] Aluminum tube, 10 gram per tube.[Period of Validity] Two years[Approval number] State medical permitment number. Z35020234 [Manufactured] By Zhangzhou Pien Tze Huang Pharmaceutical co ., Ltd.复方片仔癀含片Compound Pien Tze Huang Buccal Tablet[Medicine name]Proprietary name:Compound Pien Tze Huang Buccal TabletChinese pronunciation:Fufang Pianzaihuang Hanpian[Ingredients]Herba Wedeliae,Herba Sarcandrae,Radix Scrophulariae,Radix Ophiopogonis, Radix Glycyrrhizae, The power of Pien Tze Huang, Mentholum. [Description]It is film-coated tablets with slightly yellow-brown inside, it smells aroma, tastes sweet and cold.[Functions and actions] Relieving internal heat and deleting toxin, benefiting throat and stopping pain, producing fluid and moistening throat. Used for acute and chronic faucitis resulted from upward invasion of wind-fire and excessive heat in lung and stomach.[Specification] 0.5 gram per tablet[Usage and Dosage] For buccal use, 2 pieces a time, 5 times daily.[Adverse Reactions] Not known[Contraindications]Not be applied by pregnant women[Precautions] Not known[Storage] Preserve in tightly closed containers.[ Packing] Aluminium and plastic composite packing , 0.5 gram×12 pieces×2 sheets / boxes.[Period of Validity] Two years[Administer standard] National medicine standard WS-5047(B-0047)-2005 [Approval number] State medical permitment number. Z20050066 [Manufactured] By Zhangzhou Pien Tze Huang Pharmaceutical co ., Ltd.复方片仔癀痔疮软膏Pien Tze Huang Hemorrhoids Ointment Compositum [Medicine Name]Proprietary name : Pien Tze Huang Hemorrhoids Ointment CompositumChinese pronunciation: Fufang Pianzaihuang Zhichuang Ruangao[Ingredients]The power of Pien Tze Huang, The power of Margarita, Succinum, Borneolum Syntheticum[Description] Light brown-yellow ointment, it smells fragrant, and feel cool . [Functions and actions]Relieving internal heat and deleting toxin, dispelling stasis and easing pain, stopping bleeding and eliminating hemorrhoid. Used for internal, external or mixed hemorrhoid .[Specification]10 grams per piece.[Dosage and usage]External use only.Take suitable quantity and apply to anus or the affected part, 2~3 times a day.[Adverse Reactions] Not known[Points for attention] Not to be applied by pregnant women[Precautions] Not known[Storage] Preserve in tightly closed containers, stored in a cool place.[Packing]Aluminium tube,10 grams/tube[Period of Validity][Administer standard] National medicine standard WS-5002(B-0002)-2006 [Approval number] State medical permitment number. Z20060001 [Manufactured] By Zhangzhou Pien Tze Huang Pharmaceutical co ., Ltd.小柴胡颗粒Xiaochaihu GranulePlease read the instruction carefully and use it according to the direction or buy and use it under chemist’s suggestion.[Medicine name]Proprietary name: Xiaochaihu GranuleChinese pronunciation:Xiaochaihu Keli[Ingredients]Radix Bupleuri,Radix Scutellariae, Rhizoma Pinelliae(processed with ginger), Radix Codonopsis, Rhizoma Zingiberis Recens, Radix Glycyrrhizae, Fructus Jujubae[Description] Brown-yellow granule, it tastes tasteless and slightly pungent. [Functions and actions]Diaphoresis, dredging liver and regulating stomach . it used for alternative chill and heat, chest tightness, being perturbed and sick ,bitter mouth and non-spittle.[Specification] 4 gram each bag[Usage and Dosage]Take after it is dissolved in boiled water, three times a day and 1~2 bags a time.[Adverse Reactions] Not known[Contraindications]Not known[Precautions]1.Smoke, alcohol, piquancy ,cold, crude, fat foods are forbidden.2.Do not used the restorative patent medicine at one time when use this medicine.3.It’s not suitable for patients with chill.4.Patients with high blood pressure, cardiopathy, nephropathy, edema should use under physician’s suggestion.5.Children, pregnant women, women in lactation, oldness and infirmness should use under physician’s suggestion.6. Fever heat patient whose body temperature exceeds 38.5℃should go to see a doctor.7. The patient whose symptom haven’t been catabatic after used this medicine for 3 days should go to see a doctor.8.It should not be used in patient who has anaphylatoid reaction with this medicine, and irritability corporeity should be used with caution.9. It should not be used when the character of this medicine has changed.10. Children should be administered under the supervision of adults.11. It should be kept out of reach of children.12.If in process of using other medicine, please consult with physician or chemist before use this medicine.[Medicine reaction] If used other medicines at the same time, the medicine reaction may occur, please consult physician or chemist the correlative detail.[Storage] Preserve in tightly closed containers[Packing]10 grams per bag(with sugar),4 gram s×6 bags/box[Period of Validity] Two years[Administer standard] PHARMACOPOEIA OF THE PEOPLES’S REPUBLIC OF CHINA (2005 V olume I )[Approval number] State medical permitment number. Z35020728 [Manufactured] By Zhangzhou Pien Tze Huang Pharmaceutical co ., Ltd.小青龙颗粒Xiaoqinglong GranuleDo please read the instruction carefully and use it according to the direction or buy and use it by physician’s suggestion.[Medicine name]Proprietary name: Xiaoqinglong GranuleChinese pronunciation: Xiaoqinglong Keli[Ingredients]Herab Ephedrae, Ramulus Cinnamomi, Rhizoma Zingiberis, Radix Asari , Fructus Schisandrae , Radix Paeoniae Alba[Description]Light-brown to brown granule, or grey to light-brown, it smells slightly fragrant tastes sweet and slightly pungent.[Functions and actions]To release the exterior to resolve retained fluid, and relieve coughing, subside asthma. It’s used for foul chill, fever, adiaphoresis, asthma or difficulty in breathing and coughing with expectoration of thin phlegm due to wind-cold and retention of fluid.[Specification]5 gram each bag (No saccharose)[Usage and Dosage]Taken after dissolved in boiled water, 5 grams a time, 3 times a day.(No saccharose)[Adverse Reactions] Not known[Contraindications]Not known[Precautions ]1. Avoid Smoke, alcohol, piquancy, crude and fatness .2. Do not used the restorative patent medicine at one time when use this medicine.3 .This medicine is not suitable for the patient who cough and dyspnea, calor internus or dyspnea due to deficiency4. The patient who has bronchiectasia, lung abcess, corpulmonale or phthisic arises cough should go to see a doctor.5. High blood pressure and cardiopathy should use with cautious. Hepatitis, nephropathy, edema and other chronic patient should use under physician’s suggestion.6. Children, pregnant women, women in lactation, oldness and infirmness should use under physician’s suggestion.7.Fever heat patient whose body temperature exceeds38.5℃or hurried broken wind, get more phlegm should go to see a doctor .8. Use according to Usage and Dosage strictly, this medicine is not suitable for long-term used.9. If the symptom haven’t catabatic after used this medicine for 3 days, should go to see a doctor.10.It should not be used in patients who has anaphylatoid reaction with this medicine, and irritability corporeity should use with caution.11. It should not be used when the character of this medicine has changed.12. Children should be administered under the supervision of adult.13. It should be kept out of reach of children.14. If in process of using other medicine, please consult with physician or chemist before use this medicine.[Medicine reaction] If used other medicines at the same time, the medicine reaction may occur, please consult physician or chemist the correlative detail.[Storage] Preserve in tightly closed containers.[Packing] Aluminium and plastic composite film ,5 grams×3 bags /box[Period of Validity]: Two years[Administer standard]: PHARMACOPOEIA OF THE PEOPLES’S REPUBLIC OF CHINA (2005 V olume I )[Approval number]: State medical permitment number. Z35020729 [Manufactured]: By Zhangzhou Pien Tze Huang Pharmaceutical co ., Ltd.蜂乳胶囊Royal Jelly Capsule[Medicine name]Proprietary name: Royal Jelly CapsuleChinese pronunciation: Fengru Jiaonang[Main ingredients]Royal Jelly, amylum[Usage and Dosage] Take in 2 capsules each time ,5 times daily [Specification]0.5g×10 capsules×5 bags , 0.5g×48 capsules×3 bottles . [Storage] Avoid sun’s rays, preserve in tightly closed containers and in a cool place。

Y. Geometric stability switch criteria in delay differential systems with delay dependent p

Y. Geometric stability switch criteria in delay differential systems with delay dependent p
EDOARDO BERETTA† AND YANG KUANG‡ Abstract. In most applications of delay differential equations in population dynamics, the need of incorporation of time delays is often the result of the existence of some stage structure. Since the through-stage survival rate is often a function of time delays, it is easy to conceive that these models may involve some delay dependent parameters. The presence of such parameters often greatly complicates the task of an analytical study of such models. The main objective of this paper is to provide practical guidelines that combine graphical information with analytical work to effectively study the local stability of some models involving delay dependent parameters. Specifically, we shall show that the stability of a given steady state is simply determined by the graphs of some functions of τ which can be expressed explicitly and thus can be easily depicted by Maple and other popular software. In fact, for most application problems, we need only look at one such function and locate its zeros. This function often has only two zeros, providing thresholds for stability switches. The common scenario is that as time delay increases, stability changes from stable to unstable to stable, implying that a large delay can be stabilizing. This scenario often contradicts the one provided by similar models with only delay independent parameters. Key words. delay differential equations, stability switch, characteristic equations, stage structure, population models AMS subject classifications. 34K18, 34K20, 92D25 PII. S0036141000376086

紫杉醇联合顺铂及5-氟尿嘧啶治疗进展期胃癌的临床观察

紫杉醇联合顺铂及5-氟尿嘧啶治疗进展期胃癌的临床观察
cancer
ZHU Zhao—cheng,YAO Ya—min,Yang Fellg
Department
of
Chinese Integrative
Medwine,Honan
observe the
Provincial Tumor Hospital,Zhengzhou 450008,China.
recent
Call
chemotherapy in the treatment
of advanced gastric cancer,and toxicity
be tolerated.
【Key words】8dvanced
gastric cancer;paelitaxel;cisplatin;5一fluorouracil Modern(}neology
【Abstract】Objective:To
eisplatin and tients pathologically
were
efi%acy and toxicity of combination chemotherapy with paclitaxel plus adv柚ced gastric c蛐cer.Methods:Thirty—six measurable pa- Was comprised of paclitaxel 175mg/m2, l℃gimen was given per 28 days.All
收稿日期 修回日期 作者单位 作者简介
2009—09—22 2009—1l一02
36例患者均经病理学或细胞学检查确诊,其中男性23 例,女性13例,年龄在27岁一72岁之间,中位年龄54岁。 肿瘤部位:贲门部12例,胃体14例,胃窦10例。乳头状腺 癌6例,管状腺癌5例,黏液腺癌6例,印戒细胞癌9例,低分 化腺癌lO例。17例为局部晚期(Ⅲ或Ⅳ期,M。),19例为 远处转移胃癌患者(1V期,M。),其中肝转移9例,肺转移2 例,锁骨上淋巴结转移3例,胰腺转移2例,腹腔淋巴结转移 3例。初治26例,复治10例。所有患者均有客观可测量的 转移病灶(体检、x线、B超、Cl"、MBl),化疗前血常规、肝肾 功能及心电图正常,无严重心、肝、肺、肾功能异常,KPS评分 ≥60分,预计生存期t>3月。 1.2治疗方法

2020年职称英语理工类阅读判断习题及答案:Study

2020年职称英语理工类阅读判断习题及答案:Study

2020年职称英语理工类阅读判断习题及答案:Study Study Helps Predict Big Mediterranean QuakeScientists have found evidence that an overlooked faultin the eastern Mediterranean is likely to produce an earthquake and tsunami every 800 years as powerful as the one that destroyed Alexandria in AD 365.Using radiocarbon dating techniques,simulations and computer models,the researchers recreated the ancientdisaster in order to identify the responsible fault. ‘We are saying there is probably a repeat time of 800 years for this kind of earthquake,said Ms. Beth Shaw,an earthquake scientist at the University of Cambridge,who led the study. Scientists study past earthquakes in order to determine the future possibility of similar large shocks.Identifying the fault for the AD 365 earthquake and tsunami is important for the tens of millions of people inthe region,Ms. Shaw said. The fault close to the southwest coast of Crete last produced a big enough quake to generate a tsunami about 1300,which means the next powerful one could come in the next 100 years,she added in a telephone interview.Ms. Shaw and her colleagues calculate the likelyintervals by measuring the motion of either side of the fault to find how often such large earthquakes would have to occur to account for that level of motion,she said. Their computer model suggested an 8 magnitude quake on the fault would produce a tsunami that floods the coastal regions of Alexandria and North Africa,the southern coast of Greece and Sicily all the way up the Adriati to Dubrovnik. This would besimilar to the ancient quake in AD 365 that caused widespread destruction in much of Greece and unleashed a tsunami that flooded Alexandria and the Nile Delta,likely killing tens of thousands of people,she said.练习:1.The fault,which was overlooked before,has been closely studied by scientists.A RightB WrongC Not mentioned2.It is fun to identify the fault for the AD 365 earthquake and tsunami.A RightB WrongC Not mentioned3.Radiocarbon dating techniques can be used to identify the age of the earth.A RightB WrongC Not mentioned4.Scientists predict that the next powerful earthquake in the eastern Mediterranean may take place sometime before 2100.A RightB WrongC Not mentioned5.Ms. Shaw has her colleagues help her in the study of earthquake prediction.A RightB WrongC Not mentioned6.Ms. Shaw measured the movement of either side of the fault to identify the magnitude of the earthquake takingplace in AD 365.A RightB WrongC Not mentioned7.The earthquake prediction devices developed by Ms. Shaw are being widely used in the world.A RightB WrongC Not mentioned答案与题解:1.A 文章主题是,以往科学家忽视了地中海断层的存有。

阿莫西林与阿莫西林-克拉维酸钾不良反应的对比研究

阿莫西林与阿莫西林-克拉维酸钾不良反应的对比研究
1资料与方法 1.1资料来源 从解放军药品不良反应监测中心数据库中调取 2000年3月至2010年3月有关阿莫西林和阿莫西
滴注3.0 g/次。1次/d。2组患者性别构成、年龄、体
重等一般情况差异无统计学意义(表1)。
2.2
2组患者不良反应的临床表现及其构成比 阿莫西林组患者共出现不良反应814例次,阿
药物不良反应杂志2010年12月第12卷第6期
ADRJ,December2010,Vol 12.No.6
・397・
调查研究
阿莫西林与阿莫西林一克拉维酸钾不良反应的 对比研究
刘皈阳1
于锋英2
陈超3
马亮3
王玉玉3(1解放军总医院第一附属医院药剂药理科,北京100037;2河北北方学院,河北
张家几075000;3解放军总医院药品保障中心,北京100853)

amoxicillin/clavulanate potassium involved 233 adverse reactions.The amoxicillin group comprised 220 men and 21 8 women with
mean age
of(36.4 4-19.0)years,and
the amoxicillin/clavulanate potassium group comprised 62 men and 76 women
with

mean age
of(40.4±20.9)years.The
disorders,and central
were
nervous
percentages of skin system disorders
阿奠西林(羟氨苄青霉素)是20世纪70年代用 于临床的B一内酰胺类抗菌药物,该药抗菌谱广,杀 菌能力强,对胃酸稳定,七j服吸收率在90%以}:,并 且不受食物影响,临床上广泛应用于治疗感染性疾 病。但是阿莫西林不耐青霉素酶,随着其在临床上 的广泛应用,致病菌中产B-内酰胺酶菌株的比例H 渐增高,其疗效受到严重影响。克拉维酸钾为B-内 酰胺结构,可保护阿莫西林不被B.内酰胺酶灭活, 提高其抗菌活性。目前,阿莫西林一克拉维酸钾复合 制剂的应用越来越普及,甚至超过了单用阿莫西林。 我们采用回顾性分析的方法,比较了阿莫西林及阿 莫两林-克拉维酸钾的不良反应发生情况,以期为临 床安伞用药提供参考。

丁二磺酸腺苷蛋氨酸联合门冬氨酸钾镁、恩替卡韦治疗肝内胆汁淤积性乙型肝炎的效果分析

丁二磺酸腺苷蛋氨酸联合门冬氨酸钾镁、恩替卡韦治疗肝内胆汁淤积性乙型肝炎的效果分析
•115 .
第2 期
华夏医学
第34卷
肝功能指标、凝血功能指标改善明显优于对照组(P < 〇.〇5 ) ; 研 究 组 不 良 反 应 发 生 率 9 .2 6 % ,与对照
组 5 .5 6 % 比较,差异无统计学意义(P > 0 .0 5 ) 。 结论 :丁 二 磺 酸腺苷蛋氨酸、门冬氨酸钾镁、恩替卡韦
联合治疗肝内胆汁淤积性乙型病毒性肝炎患者的效果明显提高。
关 键 词 :肝内胆汁淤积性乙型病毒性肝炎;丁 二磺酸腺苷蛋氨酸;门冬氨酸钾镁;恩替卡韦
中 图 分 类 号 :R575.1
文 献 标 志 码 :A
文 章 编 号 :1 0 0 8 -2 4 0 9 (2 0 2 1 )0 2 -0 1 1 5 -0 5
[ 收 稿 日 期 :2020-1卜 17] [ 责 任 编 辑 :向 秋 英 文 编 辑 :阳 雨 君 ]
D 0 1 : 10.19296/ki.l008-2409.2021-02-032
丁二磺酸腺苷蛋氨酸联合门冬氨酸钾镁、 恩替卡韦治疗肝内胆汁淤积性乙型肝炎的效果分析
武海涛 ' 翟可可2, 栾 凯 1b (.漯河医学高等专科学校第二附属医院a •内二科;b .医务科,河 南 漯 河 462300;2.漯河市中心医 院肿瘤内科,河 南 漯 河 462300)
性 腰 痛 的 临 床 效 果 [ J ] . 临 床 医 学 研 究 与 实 践 ,2019,4 (9) :73-75. [1 0 ] 杜昌洪.经皮穿刺低温等离子消融术治疗腰椎间盘突出 症 的 临 床 研 究 [ J ] . 现 代 医 学 与 健 康 研 究 ,2018, 15 ( 1 2 ) :67^68, [11] NEJAT F,JADIDI K.PIRHADI S,et al.A novel approach to treatment of conjunctival cyst ablation using atmospheric low-temperature plasma[J] .Clinical Ophthalmology, 2020, 1 4(12):2525-2532. [ 1 2 ] 郭 建 ,朱 冬 昀 ,张 风 银 ,等 . 中 药 内 服 联 合 射 频 消 融 术 治 疗 腰 椎 间 盘 突 出 症 的 疗 效 观 察 [ J ] .中 日 友 好 医 院 学 报 , 2017,31(2) :109-111. [13] XIAOHUI Z.JUNXI C,SHU C,et al.Clinical effect of low temperature plasma ablation under nasal endoscope in the treatment of nasal hemangioma[ J] .Journal of Vascular and Endovascular Surgery,2019,4(2) :158-160. [1 4 ] 王文东.臭氧联合射频等离子消融术治疗腰椎间盘突出 症 110例 临 床 分 析 [ J ] . 中 国 医 药 科 学 ,2017,7(21) :212214.

高二英语科学研究单选题50题

高二英语科学研究单选题50题

高二英语科学研究单选题50题1. In the famous double - slit experiment in physics, scientists _____ observe the wave - particle duality of light.A. managed toB. tried toC. succeeded toD. aimed to答案:A。

解析:manage to表示成功做到某事,在这个语境中,科学家成功地观察到了光的波粒二象性,强调结果。

try to只是试图做某事,不强调结果是否成功。

succeed后面直接接in doing sth,没有succeed to这种用法。

aim to表示目的是做某事,侧重于目的而非结果。

2. The research on gene editing, like CRISPR - Cas9, has _____ many ethical discussions.A. given rise toB. put up withC. made up forD. caught up with答案:A。

解析:give rise to表示引起、导致,基因编辑的研究引起了很多伦理讨论。

put up with忍受,make up for弥补,catch up with 赶上,这几个短语不符合句子语境。

3. Darwin's theory of evolution was based on his _____ observationsduring his voyage on the Beagle.A. extensiveB. intensiveC. expansiveD. expensive答案:A。

解析:extensive广泛的,达尔文在小猎犬号航行期间进行了广泛的观察,这为他的进化论奠定了基础。

intensive集中的、加强的,expansive广阔的、扩张的,expensive昂贵的,后三个词不符合语境。

resonant 蟺-backbonding structure

resonant 蟺-backbonding structure

resonant 蟺-backbonding structureResonance structures are representations of the different ways in which a molecule can be written using its Lewis structure. These structures help to explain the properties of molecules such as their reactivity, stability, bond angles, and bond lengths. One of the resonance structures that is important in organic chemistry is thepi-backbonding structure.In pi-backbonding, the electrons in the pi bond of a molecule flow towards the metal ion and form a new bond between the metal ion and the pi system. The new bond formed is a pi bond, with the metal ion donating electrons from its d orbitals into the pi system. This bonding interaction is often observed in coordination complexes, where the metal ion is surrounded by ligands and is in a low oxidation state.The pi-backbonding interaction is important in determining the stability of coordination complexes, as it can affect the strength of the bond between the metal ion and the ligand. In addition, the interaction can influence the electronic properties of the ligand and the metal ion, and play a role in the reactivity of the complex.One example of a coordination complex that exhibits pi-backbonding is the ferrocene molecule. Ferrocene is a sandwich complex consisting of a central iron atom sandwiched between two cyclopentadienyl rings. The pi-backbonding interaction between the iron atom and the rings is responsible for the high stability and reactivity of ferrocene.Another example is the complex between carbon monoxide and ametal ion such as nickel or iron. In this complex, the carbon monoxide molecule donates electrons from its pi bond into the d orbitals of the metal ion, forming a new pi bond between the carbon and the metal. This interaction is important in determining the properties of these metal carbonyl complexes, which are widely used in catalysis.Pi-backbonding can also be observed in the bonding between metal ions and aromatic ligands such as benzene or pyridine. In these complexes, the pi electrons in the ligand are able to interact with the d orbitals of the metal ion, forming a new pi bond between the metal and the ligand. The strength of this interaction can affect the reactivity and stability of the complex, and is an important factor in the design of metal-based catalysts for organic reactions.In summary, pi-backbonding is a bonding interaction that plays an important role in the stability, reactivity, and electronic properties of coordination complexes. This interaction can influence the strength of the bond between the metal ion and the ligand, and is an important factor in the design of new catalysts and materials. Understanding pi-backbonding is therefore crucial for the study of coordination chemistry and its applications in organic synthesis and materials science.。

外国会计职业道德参考文献三篇

外国会计职业道德参考文献三篇

外国会计职业道德参考文献三篇会计职业道德外国参考文献一:[1]Marta Gluchmanová。

Theoretical and practical aspects of a professional ethics of teaching[J]. Human Affairs,2019,27(1)。

[2]Violeta State. Ethical Behavior and Assuring the Quality of Provided Services – the Case of Accounting Firms[J]. Valahian Journal of Economic Studies,2019,8(1)。

[3]Ying Han Fan,Gordon Woodbine,Wei Cheng. A study of Australian and Chinese accountants’ attitudes towards independence issues and the impact on ethical judgements[J]. Asian Review of Accounting,2019,21(3)。

[4]William E. Shafer,Richard S. Simmons,Rita W. Y. Yip. Social responsibility, professional commitment and tax fraud[J]. Accounting, Auditing & Accountability Journal,2019,29(1)。

[5]Mohammad Nurunnabi. Auditors’ perceptions of the implementation of International Financial Reporting Standards (IFRS)in a developing country[J]. Journal of Accounting in Emerging Economies,2019,7(1)。

达那唑联合沙利度胺治疗骨髓增生异常综合征的临床研究

达那唑联合沙利度胺治疗骨髓增生异常综合征的临床研究

达那唑联合沙利度胺治疗骨髓增生异常综合征的临床研究!张永晓",付建平",刘晓$,李英华$,刘珊$,王冬梅$,陈园园$(1.衡水市哈励逊国际和平医院血液内科,河北衡水053000; 2•衡水市哈励逊国际和平医院心内科,河北衡水053000)中图分类号R977. 1;R979.5文献标志码C文章编号 1672-2124( 2019) 12-1478-04DOI 10. 14009/j.issn. 1672-2124. 2019. 12. 018摘 要 目的:探讨达那唑联合沙利度胺治疗骨髓增生异常综合征(myelo dysplastis syndromes , MDS )的临床疗效。

方法:选取2016年3月至2018年12月衡水市哈励逊国际和平医院收治的MDS 患者122例,采用随机信封法分为对照组和观察组,每组 61例。

对照组患者口服沙利度胺,观察组患者在对照组的基础上加用达那唑。

比较两组患者治疗前后炎性因子、血象、骨髓象、临床 疗效、血清环氧酶2( COX-2)及组织蛋白酶D ( Cath-D )水平、不良反应发生情况和远期生存指标的差异。

结果:治疗后,两组患者血 清,干扰素和白细胞介素10水平较治疗前明显降低,且观察组患者明显低于对照组;两组患者血象指标水平较治疗前明显升高,且 观察组患者明显高于对照组;两组患者骨髓原始细胞比例较治疗前明显降低,且观察组患者明显低于对照组,上述差异均有统计学意义"!<0.05)。

观察组患者的总有效率为88. 52%(54/61),明显高于对照组的59.02%( 36/61),差异有统计学意义(!<0.05)。

治疗后,两组患者血清COX-2、Cath-D 水平较治疗前明显降低,且观察组患者明显低于对照组,差异均有统计学意义(P<0.05)$治疗 期间,两组患者均出现胃肠道反应、嗜睡、皮疹及肝功能异常等不良反应,症状在治疗期间自行消失。

scientists study reaction to fire -回复

scientists study reaction to fire -回复

scientists study reaction to fire -回复Scientists Study Reaction to FireIntroduction:Fire is a powerful force of nature that has fascinated humans since the dawn of time. Its ability to destroy and create has made it both a necessary tool and formidable adversary. Scientists have long been intrigued by the reactions involved in fire and have conducted extensive research to better understand its behavior and effects. This article will delve into the various aspects of studying reactions to fire, examining the steps scientists have taken to gain knowledge in this field.1. Research Objectives:Scientists studying reactions to fire have several key objectives. Firstly, they aim to understand the chemical and physical processes involved in combustion. This includes investigating the individual components of fire, such as fuel, heat, and oxygen, and how they interact with each other. Additionally, scientists seek to comprehend how different materials, structures, and environmental conditions impact fire behavior. Lastly, their research focuses on developing effective fire control andprevention strategies to enhance public safety.2. Experimental Methods:To study fire's reactions, scientists employ a combination of experimental methods. One commonly used method is the controlled burn, which involves creating a controlled fire in a controlled environment. This allows researchers to observe and measure various fire properties, such as flame temperature, heat release rate, and fire spread. Advanced instrumentation, such as thermal imaging cameras and gas analyzers, are utilized to gather precise data during these experiments. Additionally, scientists study the reactions of different materials to fire through laboratory tests, such as the cone calorimeter or small-scale fire tests.3. Fire Modeling:Fire modeling plays an essential role in understanding the reactions involved in fire. Scientists utilize mathematical equations and computer simulations to simulate fire behavior under various conditions. These models take into account factors like fuel properties, ventilation, and fire dynamics to predict fire spread, smoke production, and heat release. By refining and validatingthese models with experimental data, scientists can gain insights into how different variables affect fire reactions and develop more accurate predictions.4. Firefighters' Perspectives:Collaboration with firefighters is paramount for scientists studying reactions to fire. Firefighters provide valuable insights into their experiences, offering real-life scenarios and practical perspectives. Scientists work closely with firefighters to develop and improve firefighting techniques, identify effective fire suppression agents, and understand the behavior of fires in different structures. This collaboration ensures that scientific research translates into practical applications that can enhance firefighting strategies and ultimately save lives.5. Environmental and Health Implications:Studying reactions to fire is not limited to understanding the immediate effects of fire but also extends to its environmental and health implications. For instance, scientists investigate the release of toxic gases during combustion and the subsequent impact on air quality. They study how different materials, such as plastics or wood, contribute to air pollution when burned and seek ways tomitigate these effects. Additionally, researchers evaluate the impact of fire on ecosystems, including its effects on vegetation, wildlife, and soil quality, providing valuable information for post-fire environmental restoration.6. Fire Safety and Prevention Strategies:Understanding fire reactions allows scientists to develop effective fire safety and prevention strategies. Through their research, scientists can identify fire-resistant materials, design fire-safe structures, and develop innovative fire detection and suppression systems. This knowledge is crucial for minimizing fire accidents and protecting lives and properties. By continually studying fire reactions, scientists can stay at the forefront of fire safety advancements.Conclusion:Scientific research into reactions to fire plays a vital role in our understanding of this powerful natural phenomenon. Through controlled experiments, modeling, collaboration with firefighters, and the study of environmental and health implications, scientists continue to unravel the complexities of fire behavior. By utilizingthis knowledge to develop fire safety and prevention strategies, scientists contribute to minimizing the devastating impact of fires and ensuring the well-being of communities worldwide.。

沈括英语作文

沈括英语作文

沈括:中国古代的科学巨匠**Shen Kuo: A Scientific Giant of Ancient China**In the vast annals of Chinese history, Shen Kuo stands out as a remarkable figure. A polymath par excellence, Shen Kuo made significant contributions to various fields, including physics, mathematics, astronomy, chemistry, biology, medicine, and geography. His works, particularly the "Dream Pool Essays," remain a valuable source of knowledge for scholars even today.Born in 1031, Shen Kuo was a native of Hangzhou, a city renowned for its beauty and cultural richness. He excelled in his studies from a young age, displaying a keen interest in various sciences. His curiosity and dedication to research led him to make groundbreaking discoveries in multiple fields.In the field of physics, Shen Kuo was the first to describe the magnetic needle compass, which revolutionized navigation. He also wrote about the principles of optics, explaining the refraction of light and the formation ofimages. His observations on the reflection and refraction of light were particularly noteworthy.Mathematics was another area where Shen Kuo excelled. He made contributions to the study of infinite series and the approximation of pi. His work in this field was groundbreaking, laying the foundation for further mathematical research in China.Shen Kuo's contributions to astronomy were also significant. He proposed a theory of lunar eclipses and explained the reasons for the varying brightness of the moon. He also wrote about the motion of the sun and the planets, providing insights into their orbital paths.In the field of chemistry, Shen Kuo made valuable contributions to the study of minerals and metals. He described various chemical reactions and processes, including the production of metals from ores. His observations on the properties of substances and their interactions were highly accurate.Biology and medicine were also Shen Kuo's forte. He wrote extensively on the taxonomy and classification of plants and animals, providing detailed descriptions oftheir anatomical structures. He also contributed to the study of pharmacology, describing the medicinal propertiesof various plants and minerals.Geography was another area where Shen Kuo left his indelible mark. His descriptions of the landscapes, climates, and resources of different regions were highly accurate and detailed. His geographical works provided valuable insights into the natural and cultural wealth of China.Shen Kuo's legacy is not just in his scientific contributions but also in his approach to learning. He believed in the integration of knowledge from different fields,倡导跨学科的研究方法,鼓励学者们拓宽视野,探索未知领域。

代谢物pi与信号通路

代谢物pi与信号通路

代谢物pi与信号通路英文回答:Metabolites are small molecules that are produced as a result of cellular metabolism. They can be used as substrates for further metabolic reactions or they can be excreted from the cell. Metabolites can also act as signaling molecules, transmitting information between cells and tissues.The pi metabolite is a small molecule that is produced during the glycolysis pathway. Glycolysis is the process by which glucose is broken down to produce energy. The pi metabolite can be used as a substrate for the citric acid cycle, which is another energy-producing pathway. However, the pi metabolite can also act as a signaling molecule.The pi metabolite has been shown to regulate a number of different signaling pathways. For example, the pi metabolite can inhibit the mTOR pathway, which is a keyregulator of cell growth and proliferation. The pi metabolite can also activate the AMPK pathway, which is a key regulator of energy metabolism.The pi metabolite is a versatile molecule that can play a number of different roles in cellular metabolism and signaling. The study of the pi metabolite and its role in cellular function is an active area of research.中文回答:代谢物pi与信号通路。

The Study of Chiral Molecules

The Study of Chiral Molecules

The Study of Chiral Molecules IntroductionMolecules are the building blocks of life. They exist in a wide variety of shapes and sizes, each with its own unique properties and functions. Among these, chiral molecules have become an area of intense study due to their peculiar properties and importance in the field of chemistry, biology, and medicine. In this article, we will discuss the study of chiral molecules, their discovery, properties, and applications.Discovery of Chiral MoleculesChirality is a property of chemicals where a particular molecule exists in two forms that are mirror images of each other. The two forms are non-superimposable, meaning that one cannot be converted into the other through any physical or chemical means such as rotation, translation, or even stretching. The initial discovery of chiral molecules goes back to 1848 when Louis Pasteur first observed the polarization of light in crystallized tartaric acid. Pasteur was able to separate the different mirror-image forms of tartaric acid and demonstrated that each form has distinct properties. He found that one form rotated the plane of polarized light clockwise, while the other rotated counterclockwise.Properties of Chiral MoleculesThe properties of chiral molecules are vastly different from their non-chiral counterparts. Chiral molecules are highly reactive and can interact specifically with other chiral molecules to form complex structures. They can also act as signaling molecules in biological systems and are involved in enzymatic reactions, cellular recognition, and drug-receptor interactions. However, the most striking difference between chiral and non-chiral molecules is their dissymmetric nature, leading to interactions that differ in energy, stability, and specificity of reactivity. This dissymmetry is reflected in various physical, chemical, and biological properties, including optical activity, solubility, melting point, boiling point, density, refractive index, and encapsulation properties.Applications of Chiral MoleculesThe discovery of chiral molecules has significant implications in various fields, including chemistry, biology, and medicine. One of the most significant applications of chiral chemistry is the development of chiral catalysts for asymmetric synthesis. These catalysts can control the stereochemistry of reactions and produce only one enantiomer of a chiral molecule. They are widely used in the synthesis of drugs, agrochemicals, and natural products.Another significant application of chiral molecules is in the field of drug development. Chiral drugs are widely used in the treatment of various diseases, including cancer, HIV, and Alzheimer's disease. The different enantiomers of chiral drugs can have vastly different pharmacological properties. For example, the S-enantiomer of ibuprofen is responsible for the analgesic and anti-inflammatory effects, while the R-enantiomer is inactive and can cause adverse side effects.Chiral molecules are also critical in the development of new materials. The dissymmetry of chiral molecules can lead to the formation of complex structures, including nanotubes, helices, and crystals. These structures have unique optical, electrical, and mechanical properties and can be used in the development of new sensors, detectors, and electronic devices.ConclusionIn conclusion, the study of chiral molecules has become a key area of research in various fields due to their unique properties and applications. The discovery of chiral molecules has led to significant advancements in chemistry, biology, and medicine and has paved the way for the development of new drugs, materials, and technologies. Chiral molecules continue to fascinate scientists, and research in this area is expected to remain active for many years to come.。

丹莪妇康煎膏联合醋酸甲地孕酮治疗子宫内膜异位症的疗效研究

丹莪妇康煎膏联合醋酸甲地孕酮治疗子宫内膜异位症的疗效研究

㊃论 著㊃D O I :10.3969/j.i s s n .1672-9455.2023.13.007丹莪妇康煎膏联合醋酸甲地孕酮治疗子宫内膜异位症的疗效研究*刘雨婷1,刘晓庆1ә,武琳琳2西北妇女儿童医院:1.药剂科;2.保健科,陕西西安710061摘 要:目的 探讨丹莪妇康煎膏联合醋酸甲地孕酮治疗子宫内膜异位症的疗效㊂方法 选择2020年3月至2022年3月该院收治的子宫内膜异位症患者82例为研究对象,将其随机分为观察组和对照组,每组41例㊂对照组主要予以醋酸甲地孕酮胶囊治疗,观察组在对照组基础上加用丹莪妇康煎膏治疗㊂比较两组临床疗效㊁性激素水平㊁子宫动脉血流动力学㊁卵巢储备功能及不良反应发生率㊂结果 观察组总有效率高于对照组(P <0.05)㊂治疗后观察组患者的性激素(黄体生成素㊁雌二醇㊁卵泡刺激素)水平均低于对照组(P <0.05)㊂治疗后观察组子宫动脉舒张末期血流速度㊁收缩期峰值血流速度高于对照组,搏动指数㊁阻力指数低于对照组(P <0.05)㊂治疗后观察组卵巢储备功能指标窦卵泡数量及抗苗勒管激素㊁抑制素B 水平高于对照组(P <0.05)㊂治疗期间观察组㊁对照组不良反应发生率比较,差异无统计学意义(P >0.05)㊂结论 丹莪妇康煎膏联合醋酸甲地孕酮胶囊治疗子宫内膜异位症效果显著,能够降低患者的性激素水平,改善子宫动脉血流动力学㊁卵巢储备功能,且治疗安全性良好㊂关键词:子宫内膜异位症; 丹莪妇康煎膏; 醋酸甲地孕酮胶囊; 子宫动脉血流动力学; 卵巢储备功能; 性激素中图法分类号:R 711.71文献标志码:A文章编号:1672-9455(2023)13-1855-05E f f e c t o f D a n 'eF u k a n g D e c o c t i n g P a s t e c o m b i n e d w i t h m e g e s t r o l a c e t a t e i n t r e a t i n g en d o m e t r i o s i s *L I U Y u t i n g 1,L I U X i a o q i n g 1ә,WU L i n l i n 21.D e p a r t m e n t o f P h a r m a c y ;2.D e p a r t m e n t o f He a l t h C a r e ,N o r t h w e s t W o m e n 's a n d C h i l d r e n 's H o s pi t a l ,X i 'a n ,S h a a n x i 710061,C h i n a A b s t r a c t :O b je c t i v e T o s t u d y t h e ef f e c t o f D a n 'e F u k a ng D e c o c t i n g P a s t e c o m b i n e d w i th m e g e s t r o l a c e -t a t ei n t r e a t i n g e n d o m e t r i o s i s .M e t h o d s E i g h t y-t w o p a t i e n t s w i t h e n d o m e t r i o s i s a d m i t t e d a n d t r e a t e d i n t h i s h o s p i t a l f r o m M a r c h 2020t o M a r c h 2022w e r e e n r o l l e d a s t h e s t u d y s u b j e c t s a n d r a n d o m l y d i v i d e d i n t o t h e o b -s e r v a t i o n g r o u p a n d c o n t r o l g r o u p ,41c a s e s i n e a c h g r o u p .T h e c o n t r o l g r o u p w a s m a i n l y t r e a t e d w i t h m e ge s -t r o l a c e t a t e c a p s u l e ,a n d t h e o b s e r v a t i o n g r o u p w a s t r e a t e d w i t h D a n 'e F u k a n g D e c o c t i n g Pa s t e o n t h eb a s i s o f t h ec o n t r o l g r o u p .T h e c l i n i c a l e f f i c a c y ,s e x h o r m o n e l e v e l s ,u t e r i n e a r t e r i a l h e m od yn a m i c s ,o v a r i a n r e s e r v e f u n c t i o n a n d i n c i d e n c e r a t e o f a d v e r s e r e a c t i o n s w e r e c o m p a r e d b e t w e e n t h e t w o g r o u ps .R e s u l t s T h e t o t a l e f -f e c t i v e r a t e i n t h e o b s e r v a t i o n g r o u p w a s h i g h e r t h a n t h a t i n t h e c o n t r o l g r o u p (P <0.05).T h e l u t e i n i z i n gh o r m o n e ,e s t r o g e n a n d f o l l i c l e s t i m u l a t i n g h o r m o n e l e v e l s a f t e r t r e a t m e n t i n t h e o b s e r v a t i o n g r o u p we r e l o w e r t h a n t h o s e i n t h e c o n t r o l g r o u p (P <0.05).T h e e n d -d i a s t o l i c b l o o df l o w v e l o c i t y a n d t h e p e a k s y s t o l i c v e l o c i t y o f u t e r i n e a r t e r y a f t e r t r e a t m e n t i n t h e o b s e r v a t i o ng r o u p w a shi g h e r t h a n t h a t i n t h e c o n t r o l g r o u p.T h e p u l s e i n d e x a n d r e s i s t a n c e i n d e x a f t e r t r e a t m e n t i n t h e o b s e r v a t i o n g r o u p w e r e l o w e r t h a n t h o s e i n t h e c o n t r o l g r o u p(P <0.05).T h e n u m b e r o f a n t r a l f o l l i c l e s ,a n t i -M u l l e r i a h o r m o n e a n d i n h i b i n B l e v e l s a f t e r t r e a t m e n t i n t h eo b s e r v a t i o n g r o u p w e r e h i g h e r t h a n t h o s e i n t h e c o n t r o l g r o u p (P <0.05).T h e r e w a s n o s t a t i s t i c a l l y s i g n i f i -c a n t d i f f e r e n c e i n t h e i n c i d e n c e r a t e o f a d v e r s e r e a c t i o n s d u r i n g th e t r e a t m e n t p e r i o d b e t w e e n t h e o b s e r v a t i o n g r o u p a n d t h e c o n t r o l g r o u p (P >0.05).C o n c l u s i o n D a n 'e F u k a n g D e c o c t i n g P a s t e c o m b i n e d w i t h m e ge s t r o l a c e t a t e c a p s u l e h a s a s i gn i f i c a n t e f f e c t i n t h e t r e a t m e n t o f e n d o m e t r i o s i s ,w h i c h c o u l d r e d u c e t h e l e v e l o f s e x h o r m o n e s i n t h e p a t i e n t s ,i m p r o v e t h e u t e r i n e a r t e r i a l h e m o d yn a m i c s ,o v a r i a n r e s e r v e f u n c t i o n ,m o r e o v e r w h i c h h a s g o o d t r e a t m e n t s a f e t y.K e y wo r d s :e n d o m e t r i o s i s ; D a n 'e F u k a n g D e c o c t i n g P a s t e ; m e g e s t r o l a c e t a t e c a p s u l e ; u t e r i n e a r t e r y h e m o d yn a m i c s ; o v a r i a n r e s e r v e f u n c t i o n ; s e x h o r m o n e ㊃5581㊃检验医学与临床2023年7月第20卷第13期 L a b M e d C l i n ,J u l y 2023,V o l .20,N o .13*基金项目:陕西省科技计划项目(2021Q J -421)㊂ 作者简介:刘雨婷,女,药师,主要从事妇儿疾病临床用药方面的研究㊂ ә通信作者,E -m a i l :1021297877@q q.c o m ㊂ 网络首发 h t t p s ://k n s .c n k i .n e t /k c m s 2/a r t i c l e /a b s t r a c t ?u r l I d =50.1167.R .20230331.0925.002&u n i pl a t f o r m=N Z K P T (2023-03-31)Copyright ©博看网. All Rights Reserved.子宫内膜异位症是子宫内膜的活细胞种植在子宫内膜以外位置导致的疾病,并且这种异位的内膜细胞呈病理性增生的现象[1]㊂从解剖生理学角度分析,正常情况下子宫内膜应处于子宫腔内,由于输卵管和子宫相连且与盆腔相通,使得子宫内膜细胞可经输卵管进入盆腔等处生长[2]㊂子宫内膜异位症发病后异位内膜处周围组织纤维化,并形成囊肿㊁异位结节等可导致患者出现盆腔疼痛㊁痛经及月经不调等症状,严重者可能造成不孕[3]㊂因此,对于子宫内膜异位症患者应给予积极有效的治疗干预[3]㊂该病主要治疗方法为采用孕激素㊁雄激素等进行激素替代治疗,从调理患者激素水平的角度发挥治疗作用[4]㊂醋酸甲地孕酮是一种孕激素,可抑制排卵,进而减少月经量㊁缓解痛经,还可调控异位内膜上受体的表达,使之发生与正常内膜类似的变化[5]㊂随着该方法临床应用的增多,有研究发现,单纯的激素治疗对于子宫内膜异位症存在疗效不足的问题,且长期服用激素类药物易引起较多的不良反应[6]㊂丹莪妇康煎膏有活血祛瘀㊁疏肝理气㊁止痛调经㊁化积软坚功效,既往用于治疗子宫内膜异位症有良好的效果[7]㊂而丹莪妇康煎膏联合醋酸甲地孕酮治疗子宫内膜异位症的疗效尚不明确,临床也鲜有报道㊂为此,本研究以子宫内膜异位症患者为研究对象,采用丹莪妇康煎膏联合醋酸甲地孕酮胶囊治疗,主要评估联合用药对患者的疗效,以期为临床诊疗提供参考㊂1资料与方法1.1一般资料选择2020年3月至2022年3月西北妇女儿童医院收治的子宫内膜异位症患者82例为研究对象㊂纳入标准:(1)经诊断确诊为子宫内膜异位症,符合‘子宫内膜异位症的诊治指南“[8]中相关诊断标准;(2)患者年龄>18岁,均为已接受腹腔镜手术的患者;(3)患者对醋酸甲地孕酮胶囊㊁布洛芬缓释胶囊㊁丹莪妇康煎膏无过敏且无禁忌证㊂排除标准:(1)合并其他妇科疾病患者,如子宫内膜炎㊁阴道炎等;(2)同时服用其他药物的患者;(3)基础数据不完整患者;(4)错服㊁漏服药物的患者;(5)自愿退出的患者㊂本研究通过西北妇女儿童医院医学伦理委员会审批(批件号:K Y L L20200216),患者对本研究知情同意㊂将研究对象随机分为观察组和对照组,每组41例㊂两组一般资料比较,差异无统计学意义(P>0.05),具有可比性㊂见表1㊂表1两组一般资料比较[xʃs或n(%)]组别n年龄(岁)体质量指数(k g/m2)病程(月)A S R M分期Ⅰ期Ⅱ期观察组4131.38ʃ7.0222.98ʃ3.0613.47ʃ4.4522(53.66)19(46.34)对照组4133.02ʃ7.8123.45ʃ3.4113.92ʃ4.1726(63.41)15(36.59) t/χ2-1.000-0.657-0.4720.804P0.3200.5130.6380.3701.2方法1.2.1治疗方法对照组予以醋酸甲地孕酮胶囊及布洛芬缓释胶囊治疗㊂醋酸甲地孕酮胶囊(国药准字H19991017;规格:0.16g;生产单位:南京臣功制药股份有限公司)口服,每日2次,每次0.16g,以15d为1个疗程㊂布洛芬缓释胶囊(国药准字H20193365;规格:0.3g;生产单位:华北制药股份有限公司)按需口服,每日2次,每次0.3g,疼痛症状缓解后停用㊂观察组加用丹莪妇康煎膏治疗,醋酸甲地孕酮胶囊及布洛芬缓释胶囊服用方法与对照组相同㊂丹莪妇康煎膏(国药准字Z20025253;规格:15g;生产单位:云南圣科药业有限公司)口服,每日2次,每次10g,自月经前第10~15天开始服用,连服15d为1个疗程,经期可不停药㊂两组均治疗6个疗程㊂1.2.2检测方法(1)性激素指标检测:采集两组患者治疗前1d和疗程结束后月经第7天的静脉血3 m L,以L5-5K型台式高速冷冻离心机(海南可成仪器设备公司)离心分离血清㊂离心半径5c m㊁转速8000r/m i n㊁离心30m i n后得到上清液标本㊂以M-900型全自动生化分析仪(深圳迈瑞医疗器械有限公司)检测两组黄体生成素(L H)㊁雌二醇(E2)㊁卵泡刺激素(F S H)水平,检测方法为免疫比浊法,试剂盒由上海瑞番生物科技公司㊁上海威奥生物科技公司㊁武汉湘然生物技术公司提供㊂(2)子宫动脉血流动力学指标检测:于两组治疗前后采用高分辨率D C-70P r o型超声诊断仪(南京贝登医疗股份有限公司)经阴道行多普勒超声检查,检测两组子宫动脉舒张末期血流速度(E D V)㊁搏动指数(P I)㊁收缩期峰值血流速度(P S V)㊁阻力指数(R I)㊂(3)卵巢储备功能指标检测:采集两组治疗前后的静脉血3m L,以荧光免疫分析法检测两组抗苗勒管激素(AMH)㊁抑制素B(I N H B)水平,检测仪器为T F L1600型八通道荧光免疫分析仪(济南欧莱博科技有限公司),试剂盒购自华高生物科技有限公司;采用DW-T6彩色多普勒超声诊断仪(徐州大为电子设备有限公司)检测两组治疗前后的双侧卵巢窦卵泡数量(A F C)㊂㊃6581㊃检验医学与临床2023年7月第20卷第13期 L a b M e d C l i n,J u l y2023,V o l.20,N o.13Copyright©博看网. All Rights Reserved.1.3 评价标准 临床疗效:参照文献[9]制订如下标准㊂总有效率=(治愈例数+显效例数+有效例数)/总例数ˑ100%㊂治愈:症状及体征完全消失,盆腔包块基本消失;显效:盆腔包块缩小超过一半,症状㊁体征明显减轻;有效:盆腔包块缩小ɤ50%,症状㊁体征减轻;无效:盆腔包块体积增大或未缩小,症状㊁体征无改善或加重㊂1.4 统计学处理 采用S P S S 25.0统计软件进行统计处理和分析㊂正态分布的计量资料以x ʃs 表示,组间比较行t 检验;计数资料以例数或百分率表示,组间比较行χ2检验㊂以P <0.05为差异有统计学意义㊂2 结 果2.1 两组临床疗效比较 观察组与对照组的总有效率分别为95.12%(39/41)㊁80.49%(33/41),观察组总有效率高于对照组,差异有统计学意义(P <0.05)㊂见表2㊂2.2 两组治疗前后性激素水平比较 治疗前两组性激素指标F S H ㊁L H ㊁E 2水平比较,差异无统计学意义(P >0.05)㊂治疗后两组F S H ㊁L H ㊁E 2水平低于治疗前,且观察组均低于对照组,差异均有统计学意义(P <0.05)㊂见表3㊂2.3 两组治疗前后子宫动脉血流动力学指标比较 治疗前两组子宫动脉P S V ㊁R I ㊁P I ㊁E D V 比较,差异无统计学意义(P >0.05)㊂治疗后两组子宫动脉P S V ㊁E D V 高于治疗前,而P I ㊁R I 低于治疗前,差异均有统计学意义(P <0.05);治疗后观察组子宫动脉P S V ㊁E D V 高于对照组,而P I ㊁R I 低于对照组,差异均有统计学意义(P <0.05)㊂见表4㊂表2 两组临床疗效比较[n (%)]组别n治愈显效有效无效总有效观察组4117(41.46)12(29.27)10(24.39)2(4.88)39(95.12)对照组4115(36.59)10(24.39)8(19.51)8(19.51)33(80.49)χ24.100P0.0432.4 两组治疗前后卵巢储备功能指标比较 治疗前两组卵巢储备功能指标A F C 及AMH ㊁I N H B 水平比较,差异无统计学意义(P >0.05)㊂治疗后两组A F C及AMH ㊁I N H B 水平均高于治疗前,且观察组均高于对照组,差异均有统计学意义(P <0.05)㊂见表5㊂表3 两组治疗前后性激素水平比较(x ʃs )组别nL H (m I U /m L )治疗前治疗后E 2(pm o l /L )治疗前治疗后F S H (m I U /m L )治疗前治疗后观察组4115.23ʃ3.936.92ʃ2.30*410.98ʃ83.47209.72ʃ59.11*13.17ʃ3.756.67ʃ1.54*对照组4115.12ʃ4.019.87ʃ1.96*412.31ʃ71.28316.29ʃ68.45*13.09ʃ3.689.10ʃ1.86*t 0.125-6.251-0.078-7.5450.097-6.443P0.900<0.0010.938<0.0010.923<0.001注:与同组患者治疗前比较,*P <0.05㊂表4 两组治疗前后子宫动脉血流动力学指标比较(x ʃs )组别nP S V (c m /s )治疗前治疗后E D V (c m /s)治疗前治疗后P I (%)治疗前治疗后R I (%)治疗前治疗后观察组414.01ʃ0.738.13ʃ1.34*1.91ʃ0.524.71ʃ0.98*79.12ʃ4.9745.13ʃ8.15*68.91ʃ6.9843.41ʃ5.76*对照组413.92ʃ0.717.10ʃ1.14*1.97ʃ0.543.84ʃ0.83*78.04ʃ4.8651.21ʃ7.29*69.72ʃ7.0349.01ʃ6.20*t0.5663.749-0.5124.3380.893-4.172-0.524-4.237P0.573<0.0010.610<0.0010.365<0.0010.602<0.001注:与同组患者治疗前比较,*P <0.05㊂表5 两组治疗前后卵巢储备功能指标比较(x ʃs )组别nAMH (n g /m L )治疗前治疗后I N H B (n g/L )治疗前治疗后A F C (个)治疗前治疗后观察组411.93ʃ0.493.12ʃ0.53*31.27ʃ5.4364.23ʃ7.95*8.12ʃ1.3913.56ʃ2.95*对照组411.99ʃ0.512.51ʃ0.59*31.98ʃ5.5158.36ʃ6.91*8.24ʃ1.4810.67ʃ2.88*t -0.5432.987-0.5883.568-0.3784.489P0.5880.0040.5580.0010.706<0.001注:与同组患者治疗前比较,*P <0.05㊂㊃7581㊃检验医学与临床2023年7月第20卷第13期 L a b M e d C l i n ,J u l y 2023,V o l .20,N o .13Copyright ©博看网. All Rights Reserved.2.5两组治疗安全性比较观察组㊁对照组不良反应发生率分别为14.63%(6/41)㊁9.76%(4/41),组间对比差异无统计学意义(P>0.05)㊂见表6㊂表6两组治疗后不良反应发生情况比较[n(%)]组别n头晕恶心潮热皮疹总发生观察组412(4.88)2(4.88)2(4.88)6(14.63)对照组412(4.88)1(2.44)1(2.44)4(9.76)χ20.456P0.5003讨论子宫内膜异位症在临床上有较高的发病率,其易感人群主要为育龄期女性,表现为痛经㊁月经不调㊁性交痛㊁下腹部疼痛等,影响其正常生活状态和生活质量,严重者可导致不孕[10]㊂目前临床上西医主要以激素类药物进行保守治疗,醋酸甲地孕酮胶囊是一种强效的孕激素类药物,在子宫内膜异位症治疗过程中通过调节机体的性激素水平,抑制雌激素的分泌,使正常的子宫内膜与异常的子宫内膜均萎缩㊁不活动,并对患者的子宫㊁卵巢等功能进行调节,促使内膜异位病灶消退,进而发挥治疗作用[11]㊂本研究中对照组以醋酸甲地孕酮胶囊及布洛芬缓释胶囊治疗,患者总有效率为80.49%,表明该方法具备一定的疗效,但仍有提升的空间㊂丹莪妇康煎膏具有良好的活血化瘀㊁疏肝理气等功效,既往用于妇科疾病,如子宫内膜异位症的治疗,在单纯孕激素治疗的基础上能够进一步提高患者的疗效[7]㊂本研究中观察组加用丹莪妇康煎膏治疗,患者的临床疗效有显著提升,表明该药对于子宫内膜异位症有较好的疗效㊂这是因为丹莪妇康煎膏是由莪术㊁三七㊁紫丹参㊁赤芍㊁竹叶柴胡㊁当归㊁延胡索㊁香附㊁三棱㊁甘草等中药材提取物组成㊂其中莪术具有行气破血㊁消积止痛之功效㊂三七具有活血祛瘀㊁消肿定痛之功效;紫丹参具有活血调经㊁消肿止痛㊁养血安神之功效;赤芍可清热凉血㊁散瘀止痛;竹叶柴胡则是疏肝理气㊁调经止痛之良药;当归可补血活血㊁益气养阴㊁散寒止痛;延胡索可活血行气㊁逐瘀通经㊁消肿止痛;香附具有疏肝解郁㊁理气宽中㊁调经止痛之功效;三棱则是破血行气㊁消积止痛之良药;甘草理气和中㊁调和诸药㊂全方共奏活血祛瘀㊁逐瘀通经㊁行气止痛㊁益气养阴之功效,进而对子宫内膜异位症有良好疗效[12-13]㊂据报道,子宫内膜异位症与卵巢激素密切相关,高水平卵巢激素可刺激内膜增生,导致异位病变的发生㊂因此,在子宫内膜异位症病情进展过程中,性激素指标水平呈异常高表达[14]㊂本研究发现,观察组治疗后的L H㊁E2㊁F S H水平均低于对照组,表明丹莪妇康煎膏的应用能显著改善患者的性激素水平,得益于丹莪妇康煎膏具备良好的调经止痛㊁逐瘀通经㊁调节内分泌的作用,有助于改善患者的月经周期紊乱状态,降低患者的性激素水平[15]㊂子宫内膜异位症患者由于受气滞血瘀等因素的影响,其子宫动脉的血流动力学出现异常改变,表现为子宫动脉血流速度减慢等现象㊂因此,对子宫内膜异位症患者的子宫动脉血流动力学指标检测可判断患者子宫血流情况[16]㊂本研究发现,观察组治疗后的血流动力学指标P S V㊁E D V高于对照组,而P I㊁R I低于对照组,表明丹莪妇康煎膏能够降低子宫动脉的血流阻力,增加子宫内膜的血流供应㊂这是因为丹莪妇康煎膏中的三七㊁延胡索具有活血祛瘀㊁行气散结的功效,可降低血液黏滞性,改善子宫内膜血液微循环状态和血流动力学,进而促进子宫内膜的血液循环[17]㊂子宫内膜异位症还会导致患者的卵巢功能受损,本研究观察组治疗后的A F C及I N H B㊁AMH水平均高于对照组,表明在该类患者的治疗中,应用丹莪妇康煎膏可增强其卵巢储备功能㊂这是因为丹莪妇康煎膏进入机体后能够作用于性激素结合球蛋白,进一步发挥抗雌激素正反馈作用,进而有利于卵巢激素水平的正常调节,促进排卵从而增强患者的卵巢储备功能[18]㊂本研究还发现,观察组与对照组的不良反应发生率对比,差异无统计学意义(P>0.05),提示两种药物联用安全性良好㊂综上所述,丹莪妇康煎膏联合醋酸甲地孕酮胶囊对子宫内膜异位症患者疗效显著,可降低患者L H㊁E2㊁F S H等性激素水平,增加子宫内膜的血液供应,增强卵巢储备功能且安全性良好㊂参考文献[1]B U L U N S E,Y I L MA Z B D,S I S O N C,e t a l.E n d o m e t r i o-s i s[J].E n d o c r R e v,2019,40(4):1048-1079. [2]C HA P R O N C,MA R C E L L I N L,B O R G H E S E B,e t a l.R e t h i n k i n g m e c h a n i s m s,d i a g n o s i s a n d m a n a g e m e n t o fe n d o m e t r i o s i s[J].N a t R e v E n d o c r i n o l,2019,15(11):666-682.[3]F A L C O N E T,F L Y C K T R.C l i n i c a l m a n a g e m e n t o f e n d o-m e t r i o s i s[J].O b s t e t G y n e c o l,2018,131(3):557-571.[4]B E D A I WY M A,A L L A I R E C,A L F A R A J S.L o n g-t e r mm e d i c a l m a n a g e m e n t o f e n d o m e t r i o s i s w i t h d i e n o g e s t a n d w i t h a g o n a d o t r o p i n-r e l e a s i n g h o r m o n e a g o n i s t a n d a d d-b ac k h o r m o n e t h e r a p y[J].F e r t i l S t e r i l,2017,107(3):537-548.[5]Y A N G B Y,G U L I N A Z I Y,D U Y,e t a l.M e t f o r m i n p l u sm e g e s t r o l a c e t a t e c o m p a r e d w i t h m e g e s t r o l a c e t a t e a l o n ea s f e r t i l i t y-s p a r i n g t r e a t m e n t i n p a t i e n t s w i t h a t y p i c a l e n-d o me t r i a l h y p e r p l a s i a a n d w e l l-d if f e r e n t i a t e d e n d o m e t r i a lc a n c e r:a r a nd o m i se d c o n t r o l l e d t r i a l[J].B J O G,2020,127(7):848-857.[6]黄新,黄薇.孕激素治疗子宫内膜异位症的研究进展[J].中华生殖与避孕杂志,2022,42(9):962-966.(下转第1863页)㊃8581㊃检验医学与临床2023年7月第20卷第13期 L a b M e d C l i n,J u l y2023,V o l.20,N o.13Copyright©博看网. All Rights Reserved.学技术文献出版社,2010:80-81.[9]C A R D O S O E M,R E I S C,M A N Z A N A R E S-CÉS P E D E S MC.C h r o n i c p e r i o d o n t i t i s,i n f l a m m a t o r y c y t o k i n e s,a n d i n t e r r e-l a t i o n s h i p w i t h o t h e r c h r o n i c d i s e a s e s[J].P o s t g r a d M e d, 2018,130(1):98-104.[10]陈崇崇,钟良军.龈沟液生物标志物在慢性牙周炎诊疗中的研究进展[J].口腔医学,2019,39(11):1047-1052.[11]HA O L,S HA N Q,W E I J,e t a l.L a c t o f e r r i n:m a j o r p h y s i-o l o g i c a l f u n c t i o n s a n d a p p l i c a t i o n s[J].C u r r P r o t e i n P e p t S c i,2019,20(2):139-144.[12]V I L L A V I C E N C I O A,R U E D A M S,T U R I N C G,e t a l.F a c t o r s a f f e c t i n g l a c t o f e r r i n c o n c e n t r a t i o n i n h u m a nm i l k:h o w m u c h d o w e k n o w[J].B i o c h e m C e l l B i o l, 2017,95(1):12-21.[13]R O S A L,C U T O N E A,L E P A N T O M S,e t a l.L a c t o-f e r r i n:a n a t u r a lg l y c o p r o t e i n i n v o l v e d i n i r o n a n d i n f l a m-m a t o r y h o m e o s t a s i s[J].I n t J M o l S c i,2017,18(9): 1985.[14]HA L L E T,C L E V E R D O N E R,O G D E N S K.D i s p a t c-h i n g s o n i c h e d g e h o g:m o l e c u l a r m e c h a n i s m s c o n t r o l l i n gd e p l o y m e n t[J].T r e n d s C e l l B i o l,2019,29(5):385-395.[15]C O U P L A N D C E,A N D R E I S A,A N S E L L T B,e t a l.S t r u c t u r e,m e c h a n i s m,a n d i n h i b i t i o n o f H e d g e h o g a c y l-t r a n s f e r a s e[J].M o l C e l l,2021,81(24):5025-5038. [16]程志芬,杨磊,郭留云.慢性牙周炎患者牙龈组织中S h h的表达及意义[J].郑州大学学报(医学版),2021,56(5): 614-618.[17]X U P,HO N G Y,X I E Y,e t a l.T R E M-1e x a c e r b a t e s n e u-r o i n f l a mm a t o r y i n j u r y v i a N L R P3i n f l a mm a s o m e-m e d i a-t e d p y r o p t o s i s i n e x p e r i m e n t a l s u b a r a c h n o i d h e m o r r h a g e [J].T r a n s l S t r o k e R e s,2021,12(4):643-659.[18]B O S T A N C I N,A B E T,B E L I B A S A K I S G N,e t a l.T R E M-1i s u p r e g u l a t e d i n e x p e r i m e n t a l p e r i o d o n t i t i s,a n d i t sb l oc k ade i n h i b i t s I L-17A a n d r a n k l e x p r e s s i o n a n d s u p-p r e s s e s b o n e l o s s[J].J C l i n M e d,2019,8(10):1579.[19]K I V A D A S A N N A V A R A V,P U D A K A L A K A T T I P S,HA T T A R K I S A,e t a l.E s t i m a t i o n o f l a c t o f e r r i n l e v e l s i ng i n g i v a l c r e v i c u l a r f l u i d b e f o r e a n d a f t e r p e r i o d o n t a l t h e r-a p y i n p a t i e n t s w i t h c h r o n i c p e r i o d o n t i t i s[J].C o n t e m pC l i nD e n t,2014,5(1):25-30.[20]杨磊,郭留云,程志芬,等.S h h蛋白与慢性牙周炎炎症程度的相关性研究[J].口腔医学研究,2020,36(2):131-134.[21]F E N G J Y,S U W J,C HU A N G F Y,e t a l.T R E M-1e n-h a n c e s M y c o b a c t e r i u m t u b e r c u l o s i s-i n d u c e d i n f l a mm a t o r y r e s p o n s e s i n m a c r o p h a g e s[J].M i c r o b e s I n f e c t,2021,23(1):104765.[22]L I Y,Y A N G J,WU X,e t a l.T N F-αp o l y m o r p h i s m sm i g h t i n f l u e n c e p r e d i s p o s i t i o n t o p e r i o d o n t i t i s:a m e t a-a-n a l y s i s[J].M i c r o b P a t h o g,2020,143(7):104113. [23]C HO Y E H,D E B E N E D E T T I F,T A K E U C H I T,e t a l.T r a n s l a t i n g I L-6b i o l o g y i n t o e f f e c t i v e t r e a t m e n t s[J].N a t R e v R h e u m a t o l,2020,16(6):335-345.[24]M I O S S E C P,K O L L S J K.T a r g e t i n g I L-17a n d T H17c e l l s i n c h r o n i c i n f l a mm a t i o n[J].N a t R e v D r u g D i s c o v,2012,11(10):763-776.[25]R A T H I N A S A M Y K,U L A G A N A T H A N A,R A M A M U R-T H Y S,e t a l.E s t i m a t i o n o f T N F-αL e v e l s i n s a l i v a a n d s e r-u m o f p a t i e n t s w i t h p e r i o d o n t a l h e a l t h a n d c h r o n i c p e r i o d o n-t i t i s:a c a s e-c o n t r o l s t u d y[J].J C o n t e m p D e n t P r a c t,2020,21(2):148-151.[26]陈世娟,钟良军,宋倩.汉族和哈萨克族慢性牙周炎的严重程度与I L-6和I L-17相关性分析[J].实用口腔医学杂志,2016,32(2):281-283.(收稿日期:2022-11-01修回日期:2023-03-22)(上接第1858页)[7]陈美红,黄冬花,张晓玲.丹莪妇康煎膏治疗对子宫内膜异位症患者健康相关生命质量的影响[J].中国计划生育学杂志,2019,27(10):1326-1328.[8]中华医学会妇产科学分会子宫内膜异位症协作组.子宫内膜异位症的诊治指南[J].中华妇产科杂志,2019,23(3):161-169.[9]王曼.子宫内膜异位症的中西医结合研究和诊疗标准[J].浙江中西医结合杂志,2002,12(5):265-267.[10]T A N B O T,F E D O R C S A K P.E n d o m e t r i o s i s-a s s o c i a t e di n f e r t i l i t y:a s p e c t s o f p a t h o p h y s i o l o g i c a l m e c h a n i s m s a n dt r e a t m e n t o p t i o n s[J].A c t a O b s t e t G y n e c o l S c a n d,2017, 96(6):659-667.[11]周红儿,刘平儿.腹腔镜联合药物治疗子宫内膜异位症的临床观察[J].浙江医学,2011,33(10):1543-1544. [12]叶丽亚,吴甜.丹莪妇康煎膏治疗子宫内膜异位症临床研究[J].新中医,2019,51(1):139-141.[13]朱俊,钟丽艳.丹莪妇康煎膏在子宫内膜异位症临床治疗中的应用[J].吉林中医药,2016,36(7):700-702. [14]WA N G Y,N I C HO L E S K,S H I H I M.T h e o r i g i n a n dp a t h o g e n e s i s o f e n d o m e t r i o s i s[J].A n n u R e v P a t h o l, 2020,15(1):71-95.[15]赵勤莉,陈晴,来劲松.孕三烯酮㊁丹莪妇康煎膏用于重型子宫内膜异位症术后临床疗效观察[J].兰州大学学报(医学版),2011,37(4):54-56.[16]A N I C I C R,D J U K I C M,R A K I C S,e t a l.E v a l u a t i o n o fu t e r o-o v a r i a n h e m o d y n a m i c s i n r e l a t i o n t o f e r t i l i t y a n d s t a g e o f e n d o m e t r i o s i s[J].C l i n E x p O b s t e t G y n e c o l, 2012,39(4):526-528.[17]郑秀华,郑建豹.丹莪妇康煎膏治疗子宫内膜异位症疗效观察[J].现代中西医结合杂志,2015,24(36):4056-4058.[18]黄良苗.丹莪妇康煎膏治疗子宫内膜异位症64例临床观察[J].海南医学,2012,23(10):73-74.(收稿日期:2022-10-29修回日期:2023-02-22)㊃3681㊃检验医学与临床2023年7月第20卷第13期 L a b M e d C l i n,J u l y2023,V o l.20,N o.13Copyright©博看网. All Rights Reserved.。

包头2024年10版小学4年级上册第十三次英语第六单元期末试卷(含答案)

包头2024年10版小学4年级上册第十三次英语第六单元期末试卷(含答案)

包头2024年10版小学4年级上册英语第六单元期末试卷(含答案)考试时间:80分钟(总分:100)A卷考试人:_________题号一二三四五总分得分一、综合题(共计100题)1、What is 10 - 4?A. 5B. 6C. 7D. 82、填空题:I like to _______ (学习) new languages.3、填空题:The _____ (植物领域) is a rich area for exploration and learning.4、填空题:I can take my ________ (玩具名称) anywhere I want.5、填空题:My cat likes to sit by the ______ (窗户).6、听力题:A compound is made of two or more different ______.7、What is the sound of a frog?A. RibbitB. QuackC. BarkD. Chirp8、What is the term for a period of ten years?A. CenturyB. DecadeC. MillenniumD. Era答案: B9、填空题:The capital of Italy is _____.10、听力题:An electric current flows in a _______.11、听力题:My friend is _____ (happy/sad) today.12、What do you call a large body of water surrounded by land?A. LakeB. OceanC. RiverD. Stream答案:A13、What is the capital of Anguilla?a. The Valleyb. Blowing Pointc. Sandy Groundd. Island Harbour答案:a14、听力题:The first modern Olympics were held in _______.15、听力题:The chemical formula for copper sulfate is ______.16、填空题:The __________ (历史的复兴) fosters renewal.17、What is the past tense of "eat"?A. EatenB. AteC. EatingD. Eats答案:B18、填空题:The sunflower always faces the ______ (太阳).The process of extraction separates components based on their ______.20、选择题:What do you call a group of people working together?A. TeamB. GroupC. ClubD. Class21、听力题:An _______ is a type of mixture where the components are evenly distributed.22、填空题:The first dinosaur fossil was discovered in the _______ century. (19)23、填空题:The ant works together in a _________. (群体)24、ts are ______ (耐寒) and can survive frost. 填空题:Some pla25、What do you call a person who studies space?A. BiologistB. AstronomerC. GeologistD. Physicist26、Which animal says "woof"?A. CatB. DogC. CowD. Duck答案: B27、填空题:I want to grow _____ (蔬菜) this year.28、选择题:What do we call a person who studies the Earth?A. GeographerB. GeologistC. CartographerD. All of the aboveInsects can harm __________ (植物).30、选择题:What is the name of the famous bear in the jungle?A. BalooB. Winnie the PoohC. Yogi BearD. Paddington Bear31、听力题:The study of rocks and Earth processes is called ______.32、填空题:The ________ (灌木) can be trimmed into shapes.33、听力题:The ______ helps us learn about environmental conservation.34、填空题:The ______ (植物的生长周期) can vary greatly.35、填空题:When a candle burns, it produces _______ and carbon dioxide. (热)36、听力题:The chemical formula for hexadecanoic acid is ______.37、填空题:The _____ (山羊) climbs steep hills easily. It is very agile.山羊能轻松攀爬陡峭的山丘。

  1. 1、下载文档前请自行甄别文档内容的完整性,平台不提供额外的编辑、内容补充、找答案等附加服务。
  2. 2、"仅部分预览"的文档,不可在线预览部分如存在完整性等问题,可反馈申请退款(可完整预览的文档不适用该条件!)。
  3. 3、如文档侵犯您的权益,请联系客服反馈,我们会尽快为您处理(人工客服工作时间:9:00-18:30)。

a r X i v :h e p -p h /9301241v 1 15 J a n 1993December 1992BARI-TH/92-131Study of the reactions B →D ∗ππand B →D ∗ρπPietro Colangelo a ,Fulvia De Fazio a ,Giuseppe Nardulli a,b a Istituto Nazionale di Fisica Nucleare,Sezione di Bari,Italy b Dipartimento di Fisica,Universit´a di Bari,Italy ABSTRACT We evaluate the non leptonic B meson decays B →D ∗ππand B →D ∗ρπ,in the factorization approximation and in the limit of infinitely heavy quarks,assuming the dominance of intermediate positive parity charmed resonances.We find that the branching ratios are of the order 10−3.Positive parity charmed mesons have been recently investigated by a number of authors[1,2,3,4]in the framework of the Heavy Quark Effective Theory (HQET).In particular in [1]it has been shown that the semileptonic decays :B →D ∗∗ℓν(1)can be described in terms of two universal form factors,τ1/2(ω)and τ3/2(ω),where ω=v ·v ′and v µ,v ′µare the B and D ∗∗meson four-velocities respectively.In eq.(1)D ∗∗is one of the four positive parity charmed mesons:2+3/2,1+3/2,1+1/2,0+1/2,that one expects in the infinite heavy quark mass limit;here we employ the notation JPs ℓ,where s ℓ=1/2or 3/2is the total angular momentum of the light degrees of freedom.The form factor τ3/2(ω)describes the decays into the 2+3/2and 1+3/2states,whereas τ1/2(ω)is related to the 1+1/2(ω)and 0+1/2states.Both form factors have been estimated in [2]by using the QCD sum rules approach.The 2+3/2state has been observed experimentally [5]with a mass of 2460MeV :it is denoted by D ∗2(2460).The 1+3/2meson has to be basically identified with D 1(2420)1.As shown in refs.[3,4]they are both narrow (Γ≤20MeV )since their strong decays occur in D -wave,in contrast with the states D 0(the 0+1/2state)and D ′1(the 1+1/2state)that canalso decay by S -wave.On the experimental side,some evidence has been gathered on the semileptonic decays (1)[6,7],but it is not yet conclusive.A different way to study the transition B →D ∗∗is by the non leptonic reactions [8]:B →D ∗ππ(2)B →D ∗ρπ(3)which can occur by the intermediate production of positive parity resonances with subse-quent decay into D ∗π.Examples of these processes are as follows:B −→D ∗∗0π−→D ∗+π−π−(4)B −→D ∗∗0ρ−→D ∗+π−ρ−(5)¯B 0→D ∗0π+π−(6)where in the last case we could have either D ∗0ρ0or D ∗∗+π−as intermediate resonant states.In this letter we wish to study the processes (4-6)in the framework of the factorization approximation.This approach has first been proposed by Feynman [9],and then has been extensively applied by Bauer,Stech and Wirbel (BWS)[10]and by a number of other authors 2.As well known,in this approximation one considers matrix elements of the weak non leptonic effective hamiltonianH NL =G 2V ∗cb V ud :a 1¯c γµ(1−γ5)b ¯dγµ(1−γ5)u +a 2¯dγµ(1−γ5)b ¯c γµ(1−γ5)u :(7)and evaluates them by inserting the hadronic vacuum state between the V −A quark currents appearing in (7);the constants a 1and a 2are given by:a 1=c 1+c 2N c (9)where c 1=1.1and c 2=−0.24are Wilson coefficients evaluated at the b −quark mass scale.As for N c ,experimental data for B →Dπand B →Dρseem to favour the value of the BWS model [10]N =∞(see e.g.[11])instead of the value N c =3;we shall comment on this point later on.A test of factorization has been worked out in ref.[13],where the experimental ratio between the ¯B0→D ∗+π−non leptonic width and semileptonic spectrum d Γ(¯B 0→D ∗+ℓ−¯ν)m B m D ξ(v ·v ′)(v +v ′)µ(10)<D ∗(v ′,ǫ)|(V −A )µ(0)|B (v )>=√m B m D ∗∗τ1/2(v ·v ′)(v −v ′)µ(12)<D ′1(v ′,ǫ)|(V −A )µ(0)|B (v )>=√m B m D ∗∗τ3/2(v ·v ′)[(1−(v ·v ′)2)2ǫ∗µ+(ǫ∗·v )2[−3v µ+(v ·v ′−2)v ′µ]+i (v ·v ′−1)2ǫµναβǫ∗ν(v +v ′)α(v −v ′)β] (14)<D ∗2(v ′,ǫ)|(V −A )µ(0)|B (v )>=√33(v ·v ′+1)ǫ∗µαv α+√2m B m D ∗∗|q 2≃m 2π,m 2ρin our case,we use τ1/2(v ·v ′)=0.20and τ3/2(v ·v ′)=0.19.We have also to consider the matrix elements of the currents between the vacuum and the charmed resonances in the m Q→∞limit:<0|Vµ(0)|D0(p)>=if(+)/√m cǫµ(17) where f(+)depends only logarithmically on the heavy quark mass and has been determined in ref.[2]by QCD sum rules(m c=1.35GeV):f(+)≃0.46GeV3/2.(18) In contrast,the matrix elements between the vacuum and the sℓ=3/2resonances vanish in the m Q→∞limit[2].Finally,we have to consider the weak current matrix elements between B and a light mesonπ,ρ;they can be written as follows:<π(p′)|Vµ|B(p)>=(pµ+p′µ−(m2B−m2π)q2qµF0(q2)(19) <ρ(p′,ǫ∗)|Vµ−Aµ|B(p)>=ǫµνρσǫ∗νpρp′σ2V(q2)(m B+mρ)(p+p′)µ+(ǫ∗·p)qµΓ(B−→D∗∗0(1+3/2)π−)andΓ(B−→D∗∗0(2+3/2)ρ−)Γ(B−→D∗∗0(1+3/2)π−)=4z(1+√(1−√z)2−y]2(21)andΓ(B−→D∗∗0(2+3/2)ρ−)z)2]zω2+5ω−6√m B )2,y=(mπ,mρ2√than10%from the asymptotic(m Q→∞)value reported in Table I,which provides a perhaps optimistic estimate of the theoretical errors introduced by the heavy quark mass limit.If we observe that uncertainties in the phenomenological value of N c(see eqs.(8,9)) would strongly affect only the B−decays into the0+1/2state,which however does not decay into D∗πin the infinite heavy quark limit,we can conclude that our predictions (26)-(28)should provide reasonable estimates of the non leptonic B−decays into charmed multipionfinal states.AcknowledgmentsWe thank S.Stone for having suggested this calculation,and N.Paver for useful dis-cussions.References[1]N.Isgur and M.B.Wise,Phys.Rev.D43(1991)819[2]P.Colangelo,G.Nardulli and N.Paver,Phys.Lett.B293(1992)207[3]A.F.Falk and M.Luke,Phys.Lett.B292(1992)119[4]U.Kilian,J.G.Korner and D.Pirjol,Phys.Lett.B288(1992)360[5]Particle Data Group,Review of Particle Properties,Phys.Rev.D45(1992)[6]CLEO Collab.,R.Fulton et al.,Phys.Rev.D43(1991)651;CLEO Collab.,S.Henderson et al.,Phys.Rev.D45(1992)2212[7]ARGUS Collab.,H.Albrecht et al.,preprint DESY92-146,october1992[8]S.Stone,private communication.[9]R.P.Feynman,”Symmetries in elementary particle physics”,A.Zichichi ed.p.167,Academic Press(N.Y.)1965[10]M.Bauer,B.Stech and M.Wirbel,Z.Phys.C-Particles and Fields34(1987)103[11]M.Tanimoto,K.Goda and K.Senba,Phys.Rev.D42(1990)3741[12]L.L.Chau,H.Y.Cheng,W.K.Sze,B.Tseng and H.Yao,Phys.Rev.D45(1992)3143[13]D.Bortoletto and S.Stone,Phys.Rev.Lett.65(1990)2951[14]N.Isgur and M.Wise,Phys.Lett.B232(1989)113[15]A.F.Falk,Nucl.Phys.B378(1992)79[16]M.B.Wise,Phys.Rev.D45(1992)R2188[17]R.Casalbuoni,A.Deandrea,N.Di Bartolomeo,F.Feruglio,R.Gatto and G.Nardulli,Preprint UGVA-DPT1992/11-790,BARI-TH/92-125(November1992)[18]N.Isgur,D.Scora,B.Grinstein and M.Wise,Phys.Rev.D39(1989)799[19]S.Godfrey and N.Isgur,Phys.Rev.D32(1985)189[20]A.Abada et al.,Nucl.Phys.B376(1992)172;C.R.Allton et al.,Nucl.Phys.B349(1991)1[21]M.E.Luke,Phys.Lett.B252(1990)447[22]P.Colangelo,G.Nardulli,A.A.Ovchinnikov and N.Paver,Phys.Lett.B269(1991)201Table CaptionsTab.I Widths and branching ratios(B.R.)of B−→D∗∗0(J P sℓ)π−.The B−lifetime is τB=1.2×10−12sec.The branching ratios are obtained for a1=1.1,a2=−0.24 and V cb=0.045.Tab.II Widths and branching ratios(B.R.)of B−→D∗∗0(J P sℓ)ρ−.The B−lifetime is τB=1.2×10−12sec.The branching ratios are obtained for a1=1.1,a2=−0.24 and V cb=0.045.Table IJ P sWidth(GeV) B.R.ℓ)2610−40.045)2410−40.045)2610−40.045)2310−30.045Table IIWidth(GeV) B.R. J P sℓ)2110−30.045)2110−30.045)2110−30.045)2410−50.045。

相关文档
最新文档