南京医科大学遗传学2013年考博真题
2013医学考博试题 4
2013广西医科大学内科博士考题，选择题：30分，都是临床的一些常见问题，难度不太大，估计至少能拿25分简答题：30分1.呼吸暂停综合征的定义及分型；2.上消化道出血的定义；3.心梗溶栓再通的指征；4.负反馈调节的机制，举例说明；5.小细胞低色素贫血有哪些。
论述题（内分泌专业）：40分1.病例分析（10分），给出一个病例（，难道不大应该是库欣）（1）诊断和鉴别诊断（2）要做哪些检查进行鉴别2.降糖药肠促胰素的分类和机制（15分）3.妊娠甲亢的治疗原则。
广西医科大学病理生理学博士考题，希望对来年报考的同学有帮助！一、名词解释（共5个）：钙超载、尿毒症、水中毒、混合性酸碱平衡紊乱、外源性致热源二、简答题（共3个小题）：1.低渗性脱水尿量有何改变？2.慢性肾功能衰竭时钾离子有何代谢紊乱？3.还有一题考完了之后一下子脑子短路想不起来了，等我想起来再补上三、论述题（共3个小题）：1.输入大量库存血所致缺氧与贫血性缺氧机制有何不同；2.心脏衰竭时机体如何代偿及其代偿的调控机制；3.DIC血液高凝的机制2013年广西医科大学基础医学院医学生物化学与分子生物学一名词解释1.蛋白质的二级结构2.启动子3.Klenow fragment4.内含子5.外显子6管家基因7顺式作用元件8蛋白伴侣9？10?二简答1真核生物RNA聚合酶的种类和功能？2大肠杆菌表达系统的条件3癌基因激活的方式？4简述酶的温度调节。
三讨论1蛋白质分离纯化的种类和原理2关于三羧酸循环和尿素循环的关联性？为什么说尿素循环的氮原子都直接或间接来源于体内的氨基酸？2013年广西医科大学病理学试题一、名词解释10 *3分：化生，肿瘤的异质性，围管浸润，炎性假瘤，机化，动脉瘤，肾病综合征，早期胃癌，R eed-Sternberg cell，infarction二、简答题4*5分1、一期愈合、二期愈合的主要区别？如何获得一期愈合？2、食管癌浸润性生长可引起哪些后果？3、炎症时血管通透性升高的发生机制。
2013年南京师范大学遗传学学位考试-内部资料-绝对可靠
2013年遗传学学位考试一、选择题1、在真核基因转录中起正调节作用的是（ C ）A启动子B操纵子C增强子D衰减子2、下列哪一种不是操纵子的组成部分（）A结构基因B启动子C操纵基因D阻遏物3、在人—鼠杂种细胞的细胞分裂连续世代中，在某些细胞株中将会（）A全部丢失鼠的染色体，部分保留人的染色体B全部丢失人的染色体，部分保留鼠的染色体C全部丢失鼠的染色体，全保留鼠的染色体D人和鼠的染色体都部分丢失4、F+F—杂交后的大肠杆菌中，供体和受体是（）AF+与F+ BF—与F—CF+与F—D以上均不对5、水稻体细胞2n=24条染色体，有丝分裂的子细胞染色体数为（）A6条B12条C24条D48条6、易位是由于两条染色的断裂片断错接形成的，这两条染色体是（）A姊妹染色单体B非姊妹染色单体C同染色体D非同染色体7、八倍体小黑麦种（AABBDDRR）属于（）A同源多倍体B同源异源多倍体C超倍体D异源多倍体8、DNA复制的精确性一定高于RNA的转录，这是因为（ B ）A新合成的DNA链与模板链形成了双螺旋结构，面RNA则不能。
BDNA聚合酶有3—5外切活力，面RNA无相应活力。
C脱氧核糖核苷之间氢键配对精确性高于脱氧核糖核苷与核糖核苷间的配对。
D NA聚合酶有5—3外切活力，面RNA无相应活力。
9、一个有三对杂合基因的个体自交5代，其后代群体中基因的纯合率为（）A90.91% B87.55% C93.75% D51.3%10、用尼龙线将瘿蚊的卵结扎，使核不向极细胞移动，最后这只瘿蚊发育成为（）A可育的瘿蚊B生育能力低的瘿蚊C不育的瘿蚊D发育不全的瘿蚊11、假定一群体等位基因A和a的频率为0.2和0.8，处于Hardy-Weinkerg平衡状态，经两代后杂合子的期望频率为：A0.4 B0.8 C0.32 D以上全错12、紫茉莉的枝条有绿、白色和花斑三种不同颜色，其颜色的遗传属于细胞质遗传，用雌花斑和雄花色，其后代表现为（）A绿色B白色C花斑D绿色，白色，花斑13、基因突变的遗传基础是（）A性状表现型的改变B染色体的结构变异C遗传物质D环境的改变14、在人类ABO血型系统中，IAIB基因型表现为AB血型，这种现象称为（）A不完全显性B共显性C上位性D完全显性15、Muller—5法除了可检测X染色体上的隐性致死突变外，还可检测（A ）AX染色体上的可见突变B常染色体上的显性致死突变CY染色体上的隐性突变D常染色体上的隐性致死突变二、填空题1、测交是将被测个体与杂交，由于只能产生一种含的配子，因而可以确定被测个体的基因型。
2013年全国医学博士外语统一考试英语试卷-完整版
2013MD全国医学博士外语统一考试英语试卷答题须知1．请考生首先将自己的姓名、所在考点、准考证号在试卷一答题纸和试卷二标准答题卡上认真填写清楚，并按“考场指令”要求，将准考证号在标准答题卡上划好。
2．试卷一(Paper One)答案和试卷二(Paper Two)答案都作答在标准答题卡上，不要做在试卷上。
3．试卷一答题时必须使用2B铅笔，将所选答案按要求在相应位置涂黑；如要更正，先用橡皮擦干净。
书面表达一定要用黑色签字笔或钢笔写在标准答题卡上指定区域。
4．标准答题卡不可折叠，同时答题卡须保持平整干净，以利评分。
5．听力考试只放一遍录音，每道题后有15秒左右的答题时间。
国家医学考试中心PAPER ONEPart 1 ：Listening comprehension（30%）Section ADirections:In this section you will hear fifteen short conversations between two speakers, At the end of each conversation, you will hear a questionabout what is said, The question will be read only once, After you hearthe question, read the four possible answers marked A, B, C, and D.Choose the best answers and mark the letter of your choice on theANSWER SHEET.Listen to the following exampleYou will hearWoman: I feel faint.Man: No wonder. You haven’t had a bite all day.Question: What’s the matter with the woman?You will read:A. She is sick.B. She was bitten by an ant.C. She is hungry.D. She spilled her paint.Here C is the right answer.Sample AnswerA B C DNow let’s begin with question Number 1.1. A. A cough B. Diarrhea C. A fever D. V omiting2. A. Tuberculosis B. Rhinitis C. Laryngitis D. Flu3. A. In his bag. B. By the lamp.C. In his house.D. No idea about where he left it.4. A. He’s nearly finished his work.B. He has to work for some more time.C. He wants to leave now.D. He has trouble finishing his work.5. A. A patient B. A doctor C. A teacher D. A student6. A. 2.6 B. 3.5 C. 3.9 D. 1367. A. He is the head of the hospital. B. He is in charge of Pediatrics.C. He went out looking for Dan.D. He went to Michigan on business.8. A. He has got a fever. B. He is a talented skier.C. He is very rich.D. He is a real ski enthusiast.9. A. To ask local people for help.B. To do as Romans do only when in Rome.C. Try to act like the people from that culture.D. Stay with your country fellows.10.A. She married because of loneliness.B. She married a millionaire.C. She married for money.D. She married for love.11.A. Aspirant B. Courageous C. Cautious D. Amiable12.A. He was unhappy. B. He was feeling a bit unwell.C. He went to see the doctor.D. The weather was nasty.13.A. You may find many of them on the bookseller’ shelves.B. You can buy it from almost every bookstore.C. It’s a very popular magazine.D. It doesn’t sell very well.14.A. A general practitioner. B. A gynecologist.B. An orthopedist D. A surgeon.15.A. Chemotherapy B. Radiation C. Injections D. Surgery Section BDirection:In this section you will hear one conversation and two passages, after each of which, you will hear five questions. After each question, readthe four possible answers marked A, B, C and D, Choose the bestanswer and mark the letter of your choice on the ANSWER SHEET. Dialogue16.A. It is a genetic disorder.B. It is a respiratory condition in pigs.C. It is an illness from birds to humans.D. It is a gastric ailment.17.A. Eating pork.B. Raising pigs.C. Eating chicken.D. Breeding birds.18.A. Running nose.B. Inappetence.C. Pains all over.D. Diarrhea.19.A. To stay from crowds. B. To see the doctor immediately.C. To avoid medications.D. To go to the nearby clinic.20.A. It is a debate.B. It is a TV program.C. It is a consultation.D. It is a workshop.Passage One21.A. About 10,000,000.B. About 1,000,000.C. About 100,000.D. About 10,000.22.A. A cocktail of vitamins.B. A cocktail of vitamins plus magnesium.C. The combination of vitamins A, C and E.D. The combination of minerals.23.A. The delicate structures of the inner ear. B. The inner ear cells.C. The eardrums.D. The inner ear ossicles.24.A. General Motors. B. The United Auto Workers.C. NIH.D. All of above.25.A. An industrial trial in Spain.B. Military trials in Spain and Sweden.C. Industrial trials in Spain and Sweden.D. A trial involving students at the University of Florida.Passage Two26.A. The link between obesity and birth defects.B. The link between obesity and diabetes.C. The risk of birth abnormalities.D. The harmful effects of obesity.27.A. Neural tube defects. B. Heart problems.C. Cleft lip and palate.D. Diabetes.28.A. 20 million. B. 200 million.C. 400 million.D. 40 million.29.A. A weight-loss surgery. B. A balanced diet.C. A change of life style.D. More exercise.30.A. Why obesity can cause birth defects.B. How obesity may cause birth defects.C. Why obesity can cause diabetes.D. How obesity may cause diabetes.Part II Vocabulary (10%)Section ADirection:In this section, all the sentences are incomplete. Four words or phrases, marked A B C and D .are given beneath each of them. You are tochoose the word or phrase that best completes the sentence. Then markyour answer on the ANSWER SHEET.31. Having a bird’s eye view from the helicopter, the vast pasture was __________ with beautiful houses.A. overlappedB. segregatedC. intersectedD. interspersed32. As usual, Singapore Airlines will reduce trans-pacific capacity in _________ seasons this year.A. sternB. slackC. sumptuousD. glamorous33. As to the living environment, bacteria’s needs vary, but most of them grow best ina slightly acid ___________.A. mechanismB. miniatureC. mediumD. means34. Under an unstable economic environment, employers in the construction industry place great value on ___________ in hiring and laying off workers as their volumes of work wax and wane.A. flexibilityB. moralityC. capacityD. productivity35. In a stark _________ of fortunes, the Philippines – once Asia’s second richest country – recently had to beg Vietnam to sell its rice for its hungry millions.A. denialB. reversalC. intervalD. withdrawal36. Web portal Sohu has gone a step further and called for netizens to join in an all-out boycott of __________ content.A. wholesomeB. contagiousC. vulgarD. stagnant37. Experts urge a reforesting of cleared areas, promotion of reduced-impact logging, and _____________ agriculture, to maintain the rain forest.A. sustainableB. renewableC. revivableD. merchandisable38. In the U.S., the Republican’s doctrines were slightly liberal, whereas the Democrats’ were hardly _____________.A. rationalB. radicalC. conservativeD. progressive39. Officials from the Department of Agriculture confirmed that the __________ floods and drought this summer did not affect the country’s grain output.A. ripplingB. waningC. fluctuatingD. devastating40. It is believed that the Black Death, rampant in the Medieval Europe __________, killed 1/3 of its population.A. at largeB. at randomC. on endD. on averageSection BDirections:Each of the following sentences has a word or phase underlined. There are four words or phases beneath each sentence, Choose the word orphase which can best keep the meaning of the original sentence if it issubstituted for the underlined part, Mark your answer on theANSWER SHEET.41. Christmas shoppers should be aware of the possible defects of the products sold ata discount.A. deficitsB. deviationsC. drawbacksD. discrepancies42. The goal of this training program is to raise children with a sense of responsibility and necessary courage to be willing to take on challenges in life.A. despiseB. evadeC. demandD. undertake43. After “9.11”, the Olympic Games severely taxed the security services of the host country.A. improvedB. burdenedC. inspectedD. tariffed44. The clown’s performance was so funny that the audience, adults and children alike, were all thrown into convulsions.A. a fit of enthusiasmB. a scream of frightC. a burst of laughterD. a cry of anguish45. We raised a mortgage from Bank of China and were informed to pay it off by the end of this year.A. loanB. paymentC. withdrawalD. retrieval46. The advocates highly value the “sport spirit”, while the opponent devalue it, asserting that it’s a sheer hypocrisy and self-deception.A. fineB. suddenC. finiteD. absolute47. Whenever a rattlesnake is agitated, it begins to move its tail and make a rattling noise.A. irritatedB. tamedC. stampedD. probed48. The detective had an unusual insight into criminal’s tricks and knew clearly how to track them.A. inductionB. perceptionC. interpretationD. penetration49. My little brother practices the speech repeatedly until his delivery and timing were perfect.A. presentationB. gestureC. rhythmD. pronunciation50. In recent weeks both housing and stock prices have started to retreat from their irrationally amazing highs.A. untimelyB. unexpectedlyC. unreasonablyD. unconventionallyPart III Cloze (10%)Directions: In this section there is a passage with ten numbered blanks. For each blank, there are four choices marked A, B, C, and D on the right side.Choose the best answer and mark the letter of your choice on theANSWER SHEET.Video game players may get an unexpected benefitfrom blowing away bad guys—better vision. Playing “action” video games improves a visual ability __51__ tasks like reading and driving at night, a new study says. The ability, called contrast sensitivity function, allows people to discern even subtle changes __52__ gray against a uniformly colored backdrop. It’s also one of the first visual aptitudes to fade with age. __53__ a regular regimen of action video game training can provide long-lasting visual power, according to work led by Daphne Bavelier of the University of Rochester.Previous research shows that gaming improves other visual skills, such as the ability to track several objects at the same time and __54__ attention to a series of fast-moving events. Bavelier said, “A lot of different aspects of the visual system are being enhanced, __55__.”The new work suggests that playing video games could someday become part of vision-correction treatments, which currently rely mainly on surgery or corrective lenses. “__56__ you’ve had eye surgery or get corrective lenses, exposing yourself to these games should help the optical system to recover faster and better, you need to retrain the brain to make use of the better, crisper information that’s coming in __57__ your improved eyesight,” Bavelier said.Expert action gamers in the study played first-person shooters Unreal Tournament 2004 and Call of Duty 2. A group of experienced nonaction gamers played The Sims 2, a “life simulation” video game. The players of nonaction video games didn’t see the same vision __58__, the study says. Bavelier and others are now trying to figure out exactly why action games __59__ seem to sharpen visual skill. It may be that locating enemies and aiming accurately is a strenuous, strength-building workout for the eyes, she said. Another possible __60__ is that the unpredictable, fast-changing environment of the typical action game requires players to constantly monitor entire landscapes and analyze optical data quickly.51. A. crucial forB. available inC. resulting fromD. ascribed to52. A. in disguise ofB. in shades ofC. in search ofD. in place of53. A. This is howB. That’s whyC. It is not thatD. There exists54. A. paidB. paysC. payD. paying55. A. thoughB. not to sayC. not just oneD. as well56. A. UntilB. WhileC. UnlessD. Once57. A. as opposed toB. in addition toC. as a result ofD. in spite of58. A. benefitsB. defectsC. approachesD. risks59. A. in caseB. in advanceC. in returnD. in particular60. A. effectB. reasonC. outcomeD. conclusionPart IV Reading Comprehension (30%)Directions:In this part there are six passages, each of which is followed by five questions. For each question there are four possible answers marked A, B,C, and D. Choose the best answer and mark the letter of your choice onthe ANSWER SHEET.Passage oneThere is plenty we don’t know about criminal behavior. Most crime goes unreported so it is hard to pick out trends from the data, and even reliable sets of statistics can be difficult to compare. But here is one thing we do know: those with a biological predisposition to violent behavior who are brought up in abusive homes are very likely to become lifelong criminals.Antisocial and criminal behavior tends to run in families, but no one was sure whether this was due mostly to social-environmental factors or biological ones. It turns out both are important, but the effect is most dramatic when they act together. This has been illustrated in several studies over the past six years which found that male victims of child abuse are several times as likely to become criminals and abusers themselves if they were born with a less-active version of a gene for the enzyme monoamine oxidase A (MAO-A), which breaks down neurotransmitters crucial to the regulation of aggression.Researchers recently made another key observation: kids with this “double whammy” of predisposition and an unfortunate upbringing are likely to show signs of what’s to come at a very early age. The risk factors for long-term criminality – attention deficit hyperactivity disorder, low IQ, language difficulties – can be spotted in kindergarten. So given what we now know, shouldn’t we be doing everything to protect the children most at risk?No one is suggesting testing all boys to see which variant of the MAO-A gene they have, but what the science is telling us is that we should redouble efforts to tackle abusive upbringings, and even simple neglect. This will help any child, but especially those whose biology makes them vulnerable. Thankfully there is already considerable enthusiasm in both the US and the UK for converting the latest in behavioral science into parenting and social skills: both governments have schemes in place to improve parenting in families where children are at risk of receiving poor care.Some people are uncomfortable with the idea of early intervention because it implies our behavior becomes “set” as we grow up, compromising the idea of free will. That view is understandable, but it would be negligent to ignore what the studies are telling us. Indeed, the cost to society of failing to intervene －in terms of criminal damage, dealing with offenders and helping victims of crime －is bound to be greater than the cost of improving parenting. The value to the children is immeasurable.61. Researchers have come to a consensus: to explain violent behavior ________.A. in terms of physical environmentB. form a biological perspectiveC. based on the empirical dataD. in a statistical way62. When we say that antisocial and criminal behavior tends to run in families, asindicated by the recent findings, we can probably mean that ___________.A. a particular gene is passed on in familiesB. child abuse will lead to domestic violenceC. the male victims of child abuse will pass on the tendencyD. the violent predisposition is exclusively born of child abuse63. The recent observation implicated that to check the development of antisocialand criminal behavior ___________.A. boys are to be screened for the biological predispositionB. high-risk kids should be brought up in kindergartenC. it is important to spot the genes for the risk factorsD. active measures ought to be taken at an early age64. To defend the argument against the unfavorable idea, the author makes it apoint to consider ___________.A. the immeasurable value of the genetic research on behaviorB. the consequences of compromising democracyC. the huge cost of improving parenting skillsD. the greater cost of failing to intervene65. Which of the following can be the best title for the passage?A. Parenting Strategies for KidsB. The Making of a CriminalC. Parental EducationD. Abusive ParentingPassage twoAfter 25 years battling the mother of all viruses, have we finally got the measure of HIV? Three developments featured in this issue collectively give grounds for optimism that would have been scarcely believable a year ago in the wake of another failed vaccine and continuing problems supplying drugs to all who need them.Perhaps the most compelling hope lies in the apparent “cure” of a man with HIV who had also developed leukemia. Doctors treated his leukemia with a bone marrow transplant that also vanquished the virus. Now US Company Sangamo Biosciences is hoping to emulate the effect patients being cured with a single shot of gene therapy, instead of taking antiretroviral drugs for life.Antiretroviral therapy (ART) is itself another reason for optimism. Researchers at the World Health Organization have calculated that HIV could be effectively eradicated in Africa and other hard-hit places using existing drugs. The trick is to test everyone often, and give those who test positive ART as soon as possible. Because the drugs rapidly reduce circulating levels of the virus to almost zero, it would stop people passing it on through sex. By blocking the cycle of infection in this way, the virus could be virtually eradicated by 2050.Bankrolling such a long-term program would cost serious money – initially around $3.5 billion a year in South Africa alone, ring to $85 billion in total. Huge as it sounds, however, it is peanuts compared with the estimated $1.9 trillion cost of the Iraq war, or the $700 billion spent in one go propping up the US banking sector. It also look small beer compared with the costs of carrying on as usual, which the WHO says can only lead to spiraling cases and costs.The final bit of good news is that the cost of ART could keep on falling. Last Friday, GlaxoSmithKline chairman Andrew Witty said that his company would offer all its medicines to the poorest countries for at least 25 per cent less than the typical price in rich countries. GSK has already been doing this for ART, but the hope is that the company may now offer it cheaper still and that other firms will follow their lead.No one doubt the devastation caused by AIDS. In 2007, 2 million people died and 2.7 million more contracted the virus. Those dismal numbers are not going to turn around soon – and they won’t turn around at all without huge effort and investment. But at least there is renewed belief that, given the time and money, we can finally start riddling the world of this most fearsome of viruses.66. Which is the following can be most probably perceived beyond the first paragraph?A. The end of the world.B. A candle of hope.C. A Nobel prize.D. A Quick Fix.67. According to the passage, the apparent “cure” of the HIV patient who had alsodeveloped leukemia would ___________.A. make a promising transition from antiretroviral medication to gene therapyB. facilitate the development of effective vaccines for the infectionC. compel people to draw an analogy between AIDS and leukemiaD. would change the way we look at those with AIDS68. As another bit of good news, ___________.A. HIV will be virtually wiped out first in AfricaB. the cycle of HIV infection can be broken with ARTC. the circulating levels of HIV have been limited to almost zeroD. the existing HIV drugs will be enhanced to be more effective in 25 years69. The last reason for optimism is that ___________.A. governments will invest more in improving ARTB. the cost of antiretroviral therapy is on the declineC. everybody can afford antiretroviral therapy in the worldD. the financial support of ART is coming to be no problem70. The whole passage carries a tone of ___________.A. idealismB. activismC. criticismD. optimismPassage ThreeArchaeology can tell us plenty about how humans looked and the way they lived tens of thousands of years ago. But what about the deeper questions? Could early humans speak, were they capable of self-conscious reflection, did they believe in anything?Such questions might seem to be beyond the scope of science. Not so. Answering them is the focus of a burgeoning field that brings together archaeology and neuroscience. It aims to chart the development of human cognitive powers. This is not easy to do. A skull gives no indication of whether its owner was capable of speech, for example. The task then is to find proxies (替代物)for key traits and behaviors that have stayed intact over millennia.Perhaps the most intriguing aspect of this endeavor is teasing out the role of culture as a force in the evolution of our mental skills. For decades, development of the brain has been seen as exclusively biological. But increasingly, that is being challenged.Take what the Cambridge archaeologist Colin Renfrew calls “the sapient (智人的) paradox (矛盾)”. Evidence suggests that the human genome, and hence the brain, has changed little in the past 60,000 years. Yet it wasn’t until about 10,000 years ago that profound changes took place in human behavior: people settled in villages and built shrines. Renfrew’s paradox is why, if the hardware was in place, did it take so long for humans to start changing the world?His answer is that the software – the culture – took a long time to develop. In particular, the intervening time saw humans vest (赋予) meaning in objects and symbols. Those meanings were developed by social interaction over successive generations,passed on through teaching, and stored in the neuronal connections of children.Culture also changes biology by modifying natural selection, sometimes in surprising ways. How is it, for example, that a human gene for making essential vitamin C became blocked by junk DNA? One answer is that our ancestors started eating fruit, so the pressure to make vitamin C “relaxed” and the gene became unnecessary. By this reasoning, early humans then became addicted to fruit, and any gene that helped them to find it was selected for.Evidence suggests that the brain is so plastic that, like genes, it can be changed by relaxing selection pressure. Our understanding of human cognitive development is still fragmented and confused, however. We have lots of proposed causes and effects, and hypotheses to explain them. Yet the potential pay-off makes answers worth searching for. If we know where the human mind came from and what changed it, perhaps we can gauge where it is going. Finding those answers will take all the ingenuity the modern human mind can muster.71. The questions presented in the first paragraph ___________.A. seem to have no answers whateverB. are intended to dig for ancient human mindsC. are not scientific enough to be answered hereD. are raised to explore the evolution of human appearance72. The scientists find the proxy to be ___________.A. the role of cultureB. the passage of timeC. the structure of a skullD. the biological makeup of the brain73. According to Renfrew’s paradox, the transition from 60,000 to 10,000 years agosuggests that ___________.A. human civilization came too lateB. the hardware retained biologically staticC. it took so long for the software to evolveD. there existed an interaction between gene and environment74. From the example illustrating the relation between culture and biology, wemight conclude that ___________.A. the mental development has not been exclusively biologicalB. the brain and culture have not developed at the same paceC. the theory of natural selection applies to human evolutionD. vitamin C contributes to the development of the brain75. Speaking of the human mind, the author would say that ___________.A. its cognitive development is extremely slowB. to know its past is to understand its futureC. its biological evolution is hard to predictD. as the brain develops, so as the mindPassage FourDespite the numerous warnings about extreme weather, rising sea levels and mass extinctions, one message seems to have got lost in the debate about the impact of climate change. A warmer world won’t just be inconvenient. Huge swathes (片) of it, including most of Europe, the US and Australia as well as all of Africa and China will actually be uninhabitable--- too hot, dry or stormy to sustain a human population.This is no mirage. It could materialize if the world warms by an average of just 4°C, which some models predict could happen as soon as 2050. This is the world our children and grandchildren are going to have to live in. So what are we going to do about it?One option is to start planning to move the at-risk human population to parts of the world where it will still be cool and wet. It might seem like a drastic move, but this thought experiment is not about scaremongering (危言耸听). Every scenario is extrapolated from predictions of the latest climate models, and some say that 4°C may actually turn out to be a conservative estimate.Clearly this glacier-free, desertified world---with its human population packed into high-rise cities closer to the poles---would be a last resort. Aside from anything else, it is far from being the most practical option: any attempt at mass migration is likely to fuel wars, political power struggles and infighting.So what are the alternatives? The most obvious answer is to radically reduce carbon dioxide levels now, by fast-tracking green technologies and urgently implementing energy-efficient measures. But the changes aren’t coming nearly quickly enough and global emissions are still rising. As a result, many scientists are now turning to “Earth’s plan B”.Plan B involves making sure we have large scale geoengineering technologies ready and waiting to either suck CO2 out of the atmosphere or deflect the sun’s heat. Most climate scientists were once firmly against fiddling with the Earth’s thermostat, fearing that it may make a bad situation even worse, or provide politicians with an excuse to sit on their hands and do nothing.Now they reluctantly acknowledge the sad truth that we haven’t managed to reorder the world fast enough to reduce CO2 emissions and that perhaps, given enough funding research and political muscle, we can indeed design, test and regulate geoengineering projects in time to avert the more horrifying consequences of climate change.Whatever we do, now is the time to act. The alternative is to plan for a hothouse world that none of us would recognize as home.76. To begin with, the author is trying to remind us of ____________.A. the likelihood of climate change making life inconvenientB. the warning against worsening climate changeC. the inevitable consequence of global warmingD. the misconception of a warmer world77. As the thought experiment shows, those at risk from global warming will ____________.A. live with the temperature raised by an average of 4°CB. have nowhere to go but live in the desertC. become victims as soon as 2050D. move closer to the poles78. It is clear from the passage that a practical approach to global warming is _________.A. to reduce massively CO2 emissionsB. to take protective measures by 2025C. to prepare a blueprint for mass migrationsD. to launch habitual constructions closer to the poles。
2012-2013第二学期遗传学-农学院试卷A答案
2012─ 2013学年第2学期《普通遗传学》课程考试试卷(A卷)一、名词解释（每题2分，共20分）。
1、同源染色体：指形态、结构和功能相似的一对染色体，他们一条来自父本，一条来自母本。
2、等位基因：位于同源染色体上，位点相同，控制着同一性状的基因。
3、一因多效：一个基因也可以影响许多性状的发育现象。
4、基因定位：确定基因在染色体上的位置。
主要是确定基因之间的距离和顺序。
5、重组DNA技术：它是指在体外将不同来源的DNA进行剪切和重组，形成镶嵌DNA 分子，然后将之导入宿主细胞，使其扩增表达，从而使宿主细胞获得新的遗传特性，形成新的基因产物。
6.测交：将待测个体与隐性个体杂交，根据杂交后代中表现型的种类和比例推测待测个体的基因型，这种杂交方式称为测交。
7. 中性突变（nonssense mutation）：是指突变基因不影响生物的生存和生长发育，如小麦粒色的变化、芒的有无。
8. 基因组：一个物种的单倍体细胞中所含有的遗传物质的总和称为该物种的基因组。
9. 广义遗传力：遗传方差占表型方差的百分比。
10细胞质遗传：由细胞质内的基因即细胞质基因所决定的遗传现象和遗传规律叫做，又称染色体外遗传、核外遗传、母体遗传等。
二、填空题 (每空 0.5分，共 10 分)1．①20 ②１０③１０④３０⑤２０2．①1/16 ②1/83．①9:7②9:6:1 ③12:3:14．①剂量②半不育③抑制交换5．①单体②三体6．①随机交配②基因③一代随机交配7．①限制性核酸内切酶②质粒、病毒、噬菌体三、选择题（请将答案填写在相应得表格中。
每题1分，共10分）四、判断题（正确的画“√”，错的画“×”，答案填写在相应得表格中。
每题1分，五、问答题 (每小题 6 分，共 30 分)1、有丝分裂与减数分裂有何最基本的区别？以最简要方式指出减数分裂过程中染色体减半的原因？答：减数分裂：（1）包括两次分裂，第一次是减数的，第二次是等数的。
考博外科学——精选推荐
考博外科学外科学总论（共50分）⼀名词解释：1.基因诊断2.⾼温灭菌法3.NHSTR4.GHTRS5.MODS⼆简答题：1 简述外科疾病的分类2 外科⼿术进⾏中的⽆菌原则3 感染性休克的治疗三问答题低渗性缺⽔的定义病因临床表现诊断治疗普外科各论（50分）⼀名词解释mastopathy 原发性腹膜炎strangulated hernia （狂晕刚意识到答成绞窄性肠梗阻了）abdominal compartment syndrome 第五个忘了⾼选择⾏迷⾛神经切断术（英⽂）⼆问答题甲状腺功能亢进症的病因术前术中注意事项⼿术适应症⼿术禁忌症术后常见并发症及处理原则原发性肝癌的病因病理临床表现诊断和鉴别诊断治疗2007年第⼆军医⼤学考博普通外科学⼀、多选题（12题，每题1分）1、腹腔镜⼿术禁忌：2、能叩诊出移动性浊⾳的腹腔积液：A、100ml B、200ml C、300ml D、400ml E、⼤于500ml3、急性胰腺炎⾎淀粉酶的变化：4、胆囊癌最佳的诊断⽅法：B超、CT、ERCP、？、？5、⼩⼉肠扭转病例6、肝脓肿病例7、以下胃、⼗⼆指肠穿孔描述不正确的是：⼆、填空题（8分）1、影响胃癌预后的因素有：（7空）2、下消化道出⾎的诊断⽅法有：（5空）3、下肢深静脉栓塞分为四型：_____型（4空）三、名词解释（6分，每题2分）1、buerger病2、charcot 综合征3、TME四、问答题1、家族性结肠息⾁病的发病原理、诊断、⼿术⽅式、术后随访原则？（20分）2、甲亢术后并发症及处理？（24分）3、肠梗阻按梗阻原因的分类；肠梗阻的治疗原则以及⾮⼿术治疗⽅法？（30分）第三军医⼤学2013博⼠普外专业⼀、名词解释1、richer疝2、倾倒综合征（英⽂）3、布加综合征（英⽂）4、⼆、简答题1、乳腺癌根治术切除范围2、胰腺癌⼿术切除范围3、简述直肠癌超低位保肛术4、chiold分级及其临床意义三、问答题1、急性梗阻性黄疸治疗原则2、论述胃癌外科治疗的最新进展2013南京医科⼤学普外科学（总论+普外）考博真题回忆版简答4分*61、创伤组织修补基本过程？2、30秒内确定⼼搏骤停的⽅法？3、输⾎后常见并发症？4、低钾的常见病因？5、营养⽀持⽅法选择原则？6、⼿术中的⽆菌原则？问答19分*41、胰腺假性囊肿的⼿术指征、⽅式、要点？2、甲状腺⼿术并发症及治疗？3、腹膜后⼗⼆指肠破裂诊断依据及治疗？4、完善的科研设计标志有哪些？第三军医⼤学2013年外科专业基础之⼈体解剖真题名词解释：胸⾻⾓纵隔膜迷路动脉韧带肺段简答脑屏障的主要特点喉的结构，运动及功能的关系胆汁的产⽣，排出的主要特点问答⽪质核束的主要特点内脏传导通路的主要特点迷⾛神经的主要特点腰丛的主要特点2013中⼭⼤学博⼠⽣⼊学考试（普外）1糖⽪质激素外科感染性休克2糖尿病围术期准备要点3开放⽓胸处理原则4影像学在泌尿系结⽯的诊断应⽤5胃癌腹腔镜禁忌6胆管囊性扩张的分型7下肢静脉体格检查名称8外科真菌感染因素和抗真菌药物9切⼝裂开预防10⿊⾊素瘤的临床表现11CEA.AFP.CA199.CA125.PSA，中⽂名称及诊断价值12门脉⾼压⾮⼿术治疗及贲门⾎管离断理由13 低渗性缺⽔的原因14乳腺癌分⼦分型及治疗建议15胃癌根治原则，根治划分，远端胃癌根治切除范围16慢性胰腺炎⼿术指征，⼿术原则，⼿术⽅式。
南医大遗传学习题
起始信号
2
一个mRNA的部分顺序和密码子编号为： ....140/CAG 141/CUC.142/UAA.143/CGG 144/UAG 145/AAU 14 6/AGC....在141和142号密码子之间插入一个鸟嘌呤(G)核苷酸， 翻译后生成的肽链的氨基酸数为 A.142 B.143 C.144
有关RNA聚合酶的叙述，哪一条是正确的 A.在转录时需RNA作引物 B.能同时催化多核苷酸链向两端延长
CC.不能从5’端延长多核苷酸链
D.以四种NMP为原料合成多核苷酸链 E.也能催化DNA的合成
1
最适合σ因子(sigma factor)的叙述是 A.它可辨别转录的终止信号，终止转录 B.它能促进mRNA结合在核糖体上 C.它是核糖体的一个亚基，能催化肽键的形成 D.它是DNA聚合酶的一个亚基，可使DNA复 制双向进行
9
DD.145
E.146
3
密码子的作用特点是
AA.一种氨基酸至少对应一个密码子
B.一种氨基酸仅和一个密码子对应 C.一种tRNA只和一个密码子对应 D.每种tRNA都与两个或两个以上的密码子对应 E.密码子和氨基酸可以直接识别
4
合成DNA的原料是 A.dAMP，dGMP，dCMP，dTMP B.ATP，GTP，CTP，UTP C.AMP，GMP，CMP，TMP
E.释放结合在启动子上的RNA聚合酶
7
DNA上的外显子（exon）是 A.不被转录的序列 B.被转录，但不被翻译的序列
CC.被转录也被翻译的序列
D.调节基因序列 E.tRNA上的序列
8
ቤተ መጻሕፍቲ ባይዱ
DNA 突变、受损后的主要修复方式是： A ．光修复 B ．错配修复
遗传学试题库及答案(打印整理)
遗传学复习资料一、《遗传学》各章及分值比例：（X%）(一) 绪论（3-5%） (2)(二) 遗传的细胞学基础（5-8%） (3)(三) 孟德尔遗传（12-15%） (8)(四) 连锁遗传和性连锁（15-18%） (16)(五) 数量性状的遗传（10-13%） (25)(六) 染色体变异（8-10%） (30)(七) 病毒和细菌的遗传（5-7%） (36)(八) 遗传物质的分子基础（5-7%） (40)(九) 基因突变（8-10%） (46)(十) 细胞质遗传（5-7%） (51)(十一) 群体遗传与进化（10-12%） (54)二、试题类型及分值：(X分/每题)：1.名词解释（3-4）2.选择题或填空题 (1-1.5)3.判断题 (1-1.5)4.问答题（5-7）5.综合分析或计算题（8-10）三、各章试题和参考答案：试题库第一章绪论（教材1章，3-5%）(一) 名词解释：1.遗传学：研究生物遗传和变异的科学。
2.遗传与变异：遗传是亲子代个体间存在相似性。
变异是亲子代个体之间存在差异。
(二)选择题或填空题：A.单项选择题：1.1900年（2）规律的重新发现标志着遗传学的诞生。
（1）达尔文（2）孟德尔（3）拉马克（4）魏斯曼2.通常认为遗传学诞生于（3）年。
（1） 1859 （2） 1865 （3）1900 （4） 19103.公认遗传学的奠基人是（3）：（1）J·Lamarck （2）T·H·Morgan （3）G·J·Mendel （4）C·R·Darwin4.公认细胞遗传学的奠基人是（2）：（1）J·Lamarck （2）T·H·Morgan （3）G·J·Mendel （4）C·R·DarwinB. 填空题：1. Mendel提出遗传学最基本的两大定律是_____和_______(分离、自由组合定律)；2. Morgan提出遗传学第三定律是____与____(连锁、交换定律)；3.遗传学研究的对象主要是____、_____、______和________（微生物、植物、动物和人类）；4.生物进化和新品种选育的三大因素是___、_____和______（遗传、变异和选择）(三) 判断题：1．后天获得的性状可以遗传（×）；2．遗传、变异和自然选择将形成物种（√）；3. 遗传、变异和人工选择将形成品种、品系（√）；4．种质决定体质，就是遗传物质和性状的关系（√）。
全国医学博士外语统一考试英语真题2013年
全国医学博士外语统一考试英语真题2013年(总分：100.00，做题时间：180分钟)一、Part 1 ：Listening comprehension（30%） (总题数：15，分数：15.00)A.A coughB.Diarrhea √C.A feverD.Vomiting解析：A.TuberculosisB.RhinitisryngitisD.Flu √解析：A.In his bag.B.By the lamp.C.In his house. √D.No idea about where he left it.解析：A.He’s nearly finished his work.B.He has to work for some more time. √C.He wants to leave now.D.He has trouble finishing his work.解析：A.A patientB.A doctorC.A teacherD.A student √解析：A.2.6B.3.5C.3.9D.136 √解析：A.He is the head of the hospital.B.He is in charge of Pediatrics.C.He went out looking for Dan.D.He went to Michigan on business. √解析：A.He has got a fever.B.He is a talented skier.C.He is very rich.D.He is a real ski enthusiast. √解析：A.To ask local people for help.B.To do as Romans do only when in Rome.C.Try to act like the people from that culture. √D.Stay with your country fellows.解析：A.She married because of loneliness.B.She married a millionaire.C.She married for money. √D.She married for love.解析：A.AspirantB.Courageous √C.CautiousD.Amiable解析：A.He was unhappy.B.He was feeling a bit unwell. √C.He went to see the doctor.D.The weather was nasty.解析：A.You may find many of them on the bookseller’ shelves.B.You can buy it from almost every bookstore.C.It’s a very popular magazine.√D.It doesn’t sell very well.解析：A.A general practitioner.B.A gynecologist. √C.An orthopedistD.A surgeon.解析：A.ChemotherapyB.RadiationC.Injections √D.Surgery解析：二、Section B (总题数：3，分数：15.00)A.It is a genetic disorder.B.It is a respiratory condition in pigs. √C.It is an illness from birds to humans.D.It is a gastric ailment.解析：A.Eating pork.B.Raising pigs. √C.Eating chicken.D.Breeding birds.解析：A.Running noseB.Inappetence √C.Pains all overD.Diarrhea解析：A.To stay from crowds. √B.To see the doctor immediately.C.To avoid medications.D.To go to the nearby clinic.解析：A.It is a debate.B.It is a TV program. √C.It is a consultation.D.It is a workshop.解析：A.About 10,000,000. √B.About 1,000,000.C.About 100,000.D.About 10,000.解析：A.A cocktail of vitamins.B.A cocktail of vitamins plus magnesium. √C.The combination of vitamins A, C and E.D.The combination of minerals.解析：A.The delicate structures of the inner ear. √B.The inner ear cells.C.The eardrums.D.The inner ear ossicles.解析：A.General Motors.B.The United Auto Workers.C.NIH √D.All of above.解析：A.An industrial trial in Spain.itary trials in Spain and Sweden.C.Industrial trials in Spain and Sweden. √D.A trial involving students at the University of Florida. 解析：A.The link between obesity and birth defects. √B.The link between obesity and diabetes.C.The risk of birth abnormalities.D.The harmful effects of obesity.解析：A.Neural tube defects.B.Heart problems.C.Cleft lip and palateD.Diabetes √解析：A.20 million.B.200 million.C.400 million. √D.40 million.解析：A.A weight-loss surgery. √B.A balanced diet.C.A change of life style.D.More exercise.解析：A.Why obesity can cause birth defects.B.How obesity may cause birth defects. √C.Why obesity can cause diabetes.D.How obesity may cause diabetes.解析：三、Part II Vocabulary (10%) (总题数：10，分数：5.00)16.Having a bird’s eye view from the helicopter, the vast pasture was __________ with beautiful houses.（分数：0.50）A.overlappedB.segregatedC.intersectedD.interspersed √解析：17.As usual, Singapore Airlines will reduce trans-pacific capacity in _________ seasons this year. （分数：0.50）A.sternB.slack √C.sumptuousD.glamorous解析：18.As to the living environment, bacteria’s needs vary, but most of them grow best in a slightly acid ___________.（分数：0.50）A.mechanismB.miniatureC.medium √D.means解析：19.Under an unstable economic environment, employers in the construction industry place great value on ___________ in hiring and laying off workers as their volumes of work wax and wane. （分数：0.50）A.flexibility √B.moralityC.capacityD.productivity解析：20.In a stark _________ of fortunes, the Philippines –once Asia’s second richest country –recently had to beg Vietnam to sell its rice for its hungry millions.（分数：0.50）A.denialB.reversal √C.intervalD.withdrawal解析：21.Web portal Sohu has gone a step further and called for netizens to join in an all-out boycott of __________ content.（分数：0.50）A.wholesomeB.contagiousC.vulgar √D.stagnant解析：22.Experts urge a reforesting of cleared areas, promotion of reduced-impact logging, and_____________ agriculture, to maintain the rain forest.（分数：0.50）A.sustainable √B.renewableC.revivableD.merchandisable解析：23.In the U.S., the Republican’s doctrines were slightly liberal, whereas the Democrats’ were hardly _____________.（分数：0.50）A.rationalB.radicalC.conservative √D.progressive解析：24.Officials from the Department of Agriculture confirmed that the __________ floods and drought this summer did not affect the country’s grain output.（分数：0.50）A.ripplingB.waningC.fluctuatingD.devastating √解析：25.It is believed that the Black Death, rampant in the Medieval Europe __________, killed 1/3 of its population.（分数：0.50）A.at large √B.at randomC.on endD.on average解析：四、Section B (总题数：10，分数：5.00)26.Christmas shoppers should be aware of the possible defects of the products sold at a discount. （分数：0.50）A.deficitsB.deviationsC.drawbacks √D.discrepancies解析：27.The goal of this training program is to raise children with a sense of responsibility and necessary courage to be willing to take on challenges in life.（分数：0.50）A.despiseB.evadeC.demandD.undertake √解析：28.After “9.11”, the Olympic Games severely taxed the security services of the host country. （分数：0.50）A.improvedB.burdened √C.inspectedD.tariffed解析：29.The clown’s performance was so funny that the audience, adults and children alike, were all thrown into convulsions.（分数：0.50）A.a fit of enthusiasmB.a scream of frightC.a burst of laughter √D.a cry of anguish解析：30.We raised a mortgage from Bank of China and were informed to pay it off by the end of this year.（分数：0.50）A.loan √B.paymentC.withdrawalD.retrieval解析：31.The advocates highly value the “sport spirit”, while the opponent devalue it, asserting that it’s a sheer hypocrisy and self-deception.（分数：0.50）A.fineB.suddenC.finiteD.absolute √解析：32.Whenever a rattlesnake is agitated, it begins to move its tail and make a rattling noise. （分数：0.50）A.irritated √B.tamedC.stampedD.probed解析：33.The detective had an unusual insight into criminal’s tricks and knew clearly how to track them.（分数：0.50）A.inductionB.perception √C.interpretationD.penetration解析：34.My little brother practices the speech repeatedly until his delivery and timing were perfect. （分数：0.50）A.presentation √B.gestureC.rhythmD.pronunciation解析：35.In recent weeks both housing and stock prices have started to retreat from their irrationally amazing highs.（分数：0.50）A.untimelyB.unexpectedlyC.unreasonably √D.unconventionally解析：五、Part III Cloze (10%) (总题数：1，分数：10.00)Video game players may get an unexpected benefit from blowing away bad guys—better vision. Playing “action” video games improves a visual ability __51__ tasks like reading and driving at night, a new study says. The ability, called contrast sensitivity function, allows people to discern even subtle changes __52__ gray against a uniformly colored backdrop. It’s also one of the first visual aptitudes to fade with age. __53__ a regular regimen of action video game training can provide long-lasting visual power, according to work led by Daphne Bavelier of the University of Rochester. Previous research shows that gaming improves other visual skills, such as the ability to track several objects at the same time and __54__ attention to a series of fast-moving events. Bavelier said, “A lot of different aspects of the visual system are being enhanced, __55__.” The new work suggests that playing video games could someday become part of vision-correction treatments, which currently rely mainly on surgery or corrective lenses. “__56__ you’ve had eye surgery or get corrective lenses, exposing yourself to these games should help the optical system to recover faster and better, you need to retrain the brain to make use of the better, crisper information that’s coming in __57__ your improved eyesight,” Bavelier said. Expert action gamers in the study played first-person shooters Unreal Tournament 2004 and Call of Duty 2. A group of experienced nonaction gamers played The Sims 2, a “life simulation” video game. The players of nonaction video games didn’t see the same vision __58__, the study says. Bavelier and others are now trying to figure out exactly why action games __59__ seem to sharpen visual skill. It may be that locating enemies and aiming accurately is a strenuous, strength-building workout for the eyes, she said. Another possible __60__ is that the unpredictable, fast-changing environment of the typical action game requires players to constantly monitor entire landscapes and analyze optical data quickly. （分数：10.00）A.crucial for √B.available inC.resulting fromD.ascribed to解析：A.in disguise ofB.in shades of √C.in search ofD.in place of解析：A.This is howB.That’s why√C.It is not thatD.There exists解析：A.paidB.paysC.payD.paying √解析：A.thoughB.not to sayC.not just one √D.as well解析：A.UntilB.WhileC.UnlessD.Once √解析：A.as opposed toB.in addition toC.as a result of √D.in spite of解析：A.benefits √B.defectsC.approachesD.risks解析：A.in caseB.in advanceC.in returnD.in particular √解析：A.effectB.reason √C.outcomeD.conclusion解析：六、Part IV Reading Comprehension (30%) (总题数：6，分数：30.00)Passage one There is plenty we don’t know about criminal behavior. Most crime goes unrepor ted so it is hard to pick out trends from the data, and even reliable sets of statistics can be difficult to compare. But here is one thing we do know: those with a biological predisposition to violent behavior who are brought up in abusive homes are very likely to become lifelong criminals.Antisocial and criminal behavior tends to run in families, but no one was sure whether this was due mostly to social-environmental factors or biological ones. It turns out both are important, but the effect is most dramatic when they act together. This has been illustrated in several studies over the past six years which found that male victims of child abuse are several times as likely to become criminals and abusers themselves if they were born with a less-active version of a gene for the enzyme monoamine oxidase A (MAO-A), which breaks down neurotransmitters crucial to the regulation of aggression. Researchers recently made another key observation: kids with this “double whammy” of predisposition and an unfortunate upb ringing are likely to show signs of what’s to come at a very early age. The risk factors for long-term criminality –attention deficit hyperactivity disorder, low IQ, language difficulties –can be spotted in kindergarten. So given what we now know, should n’t we be doing everything to protect the children most at risk? No one is suggesting testing all boys to see which variant of the MAO-A gene they have, but what the science is telling us is that we should redouble efforts to tackle abusive upbringings, and even simple neglect. This will help any child, but especially those whose biology makes them vulnerable. Thankfully there is already considerable enthusiasm in both the US and the UK for converting the latest in behavioral science into parenting and social skills: both governments have schemes in place to improve parenting in families where children are at risk of receiving poor care. Some people are uncomfortable with the idea of early intervention because it implies our behavior becomes “set” as we grow up, compromising the idea of free will. That view is understandable, but it would be negligent to ignore what the studies are telling us. Indeed, the cost to society of failing to intervene －in terms of criminal damage, dealing with offenders and helping victims of crime －is bound to be greater than the cost of improving parenting. The value to the children is immeasurable. （分数：5.00）(1).Researchers have come to a consensus: to explain violent behavior ________. （分数：1.00）A.in terms of physical environmentB.form a biological perspective √C.based on the empirical dataD.in a statistical way解析：(2).When we say that antisocial and criminal behavior tends to run in families, as indicated by the recent findings, we can probably mean that ___________. （分数：1.00）A.a particular gene is passed on in familiesB.child abuse will lead to domestic violenceC.the male victims of child abuse will pass on the tendency √D.the violent predisposition is exclusively born of child abuse解析：(3).The recent observation implicated that to check the development of antisocial and criminal behavior ___________. （分数：1.00）A.boys are to be screened for the biological predispositionB.high-risk kids should be brought up in kindergartenC.it is important to spot the genes for the risk factorsD.active measures ought to be taken at an early age √解析：(4).To defend the argument against the unfavorable idea, the author makes it a point to consider ___________. （分数：1.00）A.the immeasurable value of the genetic research on behaviorB.the consequences of compromising democracyC.the huge cost of improving parenting skillsD.the greater cost of failing to intervene √解析：(5).Which of the following can be the best title for the passage? （分数：1.00）A.Parenting Strategies for KidsB.The Making of a Criminal √C.Parental EducationD.Abusive Parenting解析：Passage two After 25 years battling the mother of all viruses, have we finally got the measure of HIV? Three developments featured in this issue collectively give grounds for optimism that would have been scarcely believable a year ago in the wake of another failed vaccine and continuing problems supplying drugs to all who need them. Perhaps the most compelling hope lies in the apparent “cure” of a man wit h HIV who had also developed leukemia. Doctors treated his leukemia with a bone marrow transplant that also vanquished the virus. Now US Company Sangamo Biosciences is hoping to emulate the effect patients being cured with a single shot of gene therapy, instead of taking antiretroviral drugs for life. Antiretroviral therapy (ART) is itself another reason for optimism. Researchers at the World Health Organization have calculated that HIV could be effectively eradicated in Africa and other hard-hit places using existing drugs. The trick is to test everyone often, and give those who test positive ART as soon as possible. Because the drugs rapidly reduce circulating levels of the virus to almost zero, it would stop people passing it on through sex. By blocking the cycle of infection in this way, the virus could be virtually eradicated by 2050. Bankrolling such a long-term program would cost serious money – initially around $3.5 billion a year in South Africa alone, ring to $85 billion in total. Huge as it sounds, however, it is peanuts compared with the estimated $1.9 trillion cost of the Iraq war, or the $700 billion spent in one go propping up the US banking sector. It also look small beer compared with the costs of carrying on as usual, which the WHO says can only lead to spiraling cases and costs. The final bit of good news is that the cost of ART could keep on falling. Last Friday, GlaxoSmithKline chairman Andrew Witty said that his company would offer all its medicines to the poorest countries for at least 25 per cent less than the typical price in rich countries. GSK has already been doing this for ART, but the hope is that the company may now offer it cheaper still and that other firms will follow their lead. No one doubt the devastation caused by AIDS. In 2007, 2 million people died and 2.7 million more contracted the virus. Those dismal numbers are not going to turn around soon –and they won’t turn around at all without huge effort and investment. But at least there is renewed belief that, given the time and money, we can finally start riddling the world of this most fearsome of viruses. （分数：5.00）(1).Which is the following can be most probably perceived beyond the first paragraph? （分数：1.00）A.The end of the world.B.A candle of hope. √C.A Nobel prize.D.A Quick Fix.解析：(2).According to the passage, the apparent “cure” of the HIV patient who had also developed leukemia would ___________. （分数：1.00）A.make a promising transition from antiretroviral medication to gene therapy √B.facilitate the development of effective vaccines for the infectionpel people to draw an analogy between AIDS and leukemiaD.would change the way we look at those with AIDS解析：(3).As another bit of good news, ___________. （分数：1.00）A.HIV will be virtually wiped out first in AfricaB.the cycle of HIV infection can be broken with ART √C.the circulating levels of HIV have been limited to almost zeroD.the existing HIV drugs will be enhanced to be more effective in 25 years解析：(4).The last reason for optimism is that ___________. （分数：1.00）ernments will invest more in improving ARTB.the cost of antiretroviral therapy is on the decline √C.everybody can afford antiretroviral therapy in the worldD.the financial support of ART is coming to be no problem解析：(5).The whole passage carries a tone of ___________. （分数：1.00）A.idealismB.activismC.criticismD.optimism √解析：Passage Three Archaeology can tell us plenty about how humans looked and the way they lived tens of thousands of years ago. But what about the deeper questions? Could early humans speak, were they capable of self-conscious reflection, did they believe in anything? Such questions might seem to be beyond the scope of science. Not so. Answering them is the focus of a burgeoning field that brings together archaeology and neuroscience. It aims to chart the development of human cognitive powers. This is not easy to do. A skull gives no indication of whether its owner was capable of speech, for example. The task then is to find proxies (替代物) for key traits and behaviors that have stayed intact over millennia. Perhaps the most intriguing aspect of this endeavor is teasing out the role of culture as a force in the evolution of our mental skills. For decades, development of the brain has been seen as exclusively biological. But increasingly, that is being challenged. Take what the Cambridge archaeologist Colin Renfrew calls “the sapient (智人的) paradox (矛盾)”. Evidence suggests that the human genome, and hence the brain, has changed little in the past 60,000 years. Yet it wasn’t until about 10,000 years ago that profound changes took place in human behavior: people settled in villages and built shrines. Renfrew’s paradox is why, if the hardware was in place, did it take so long for humans to start changing the world? His answer is that the software – the culture – took a long time to develop. In particular, the intervening time saw humans vest (赋予) meaning in objects and symbols. Those meanings were developed by social interaction over successive generations, passed on through teaching, and stored in the neuronal connections of children. Culture also changes biology by modifying natural selection, sometimes in surprising ways. How is it, for example, that a human gene for making essential vitamin C became blocked by junk DNA? One answer is that our ancestors started eating fruit, so the pressure to make vitamin C “relaxed” and the gene became unnecessary. By this reasoning, early humans then became addicted to fruit, and any gene that helped them to find it was selected for. Evidence suggests that the brain is so plastic that, like genes, it can be changed by relaxing selection pressure. Our understanding of human cognitive development is still fragmented and confused, however. We have lots of proposed causes and effects, and hypotheses to explain them. Yet the potential pay-off makes answers worth searching for. If we know where the human mind came from and what changed it, perhaps we can gauge where it is going. Finding those answers will take all the ingenuity the modern human mind can muster. （分数：5.00）(1).The questions presented in the first paragraph ___________. （分数：1.00）A.seem to have no answers whateverB.are intended to dig for ancient human minds √C.are not scientific enough to be answered hereD.are raised to explore the evolution of human appearance解析：(2).The scientists find the proxy to be ___________. （分数：1.00）A.the role of culture √B.the passage of timeC.the structure of a skullD.the biological makeup of the brain解析：(3).According to Renfrew’s paradox, the transition from 60,000 to 10,000 years ago suggests that ___________. （分数：1.00）A.human civilization came too lateB.the hardware retained biologically staticC.it took so long for the software to evolve √D.there existed an interaction between gene and environment解析：(4).From the example illustrating the relation between culture and biology, we might conclude that ___________. （分数：1.00）A.the mental development has not been exclusively biologicalB.the brain and culture have not developed at the same paceC.the theory of natural selection applies to human evolution √D.vitamin C contributes to the development of the brain解析：(5).Speaking of the human mind, the author would say that ___________. （分数：1.00）A.its cognitive development is extremely slowB.to know its past is to understand its future √C.its biological evolution is hard to predictD.as the brain develops, so as the mind解析：Passage Four Despite the numerous warnings about extreme weather, rising sea levels and mass extinctions, one message seems to have got lost in the debate about the impact of climate change.A warmer world won’t just be inconvenient. Huge swathes (片) of it, including most of Europe, the US and Australia as well as all of Africa and China will actually be uninhabitable--- too hot, dry or stormy to sustain a human population. This is no mirage. It could materialize if the world warms by an average of just 4°C, which some models predict could happen as soon as 2050. This is the world our children and grandchildren are going to have to live in. So what are we going to do about it? One option is to start planning to move the at-risk human population to parts of the world where it will still be cool and wet. It might seem like a drastic move, but this thought experiment is not about scaremongering (危言耸听). Every scenario is extrapolated from predictions of the latest climate models, and some say that 4°C may actually turn out to be a conservative estimate. Clearly this glacier-free, desertified world---with its human population packed into high-rise cities closer to the poles---would be a last resort. Aside from anything else, it is far from being the most practical option: any attempt at mass migration is likely to fuel wars, political power struggles and infighting. So what are the alternatives? The most obvious answer is to radically reduce carbon dioxide levels now, by fast-tracking green technologies and urgently implementing energy-efficient measures. But the changes aren’t coming nearly quickly enough and global emissions are still rising. As a result, many scientists are now turning to “Earth’s plan B”. PlanB involves making sure we have large scale geoengineeringtechnolo gies ready and waiting to either suck CO2 out of the atmosphere or deflect the sun’s heat. Most climate scientists were once firmly against fiddling with the Earth’s thermostat, fearing that it may make a bad situation even worse, or provide politicians with an excuse to sit on their hands and do nothing. Now they reluctantly acknowledge the sad truth that we haven’t managed to reorder the world fast enough to reduce CO2 emissions and that perhaps, given enough funding research and political muscle, we can indeed design, test and regulate geoengineering projects in time to avert the more horrifying consequences of climate change. Whatever we do, now is the time to act. The alternative is to plan for a hothouse world that none of us would recognize as home.（分数：5.00）(1).To begin with, the author is trying to remind us of ____________. （分数：1.00）A.the likelihood of climate change making life inconvenient √B.the warning against worsening climate changeC.the inevitable consequence of global warmingD.the misconception of a warmer world解析：(2).As the thought experiment shows, those at risk from global warming will ____________. （分数：1.00）A.live with the temperature raised by an average of 4°CB.have nowhere to go but live in the desertC.become victims as soon as 2050D.move closer to the poles √解析：(3).It is clear from the passage that a practical approach to global warming is _________. （分数：1.00）A.to reduce massively CO2 emissions √B.to take protective measures by 2025C.to prepare a blueprint for mass migrationsD.to launch habitual constructions closer to the poles解析：(4).Earth’s plan B is ambitious enough ___________. （分数：1.00）A.to stop climate scientists making a bad situation even worseB.to remove the sources of CO2 emissions altogetherC.to regulate geoengineering projects for efficiencyD.to manage the Earth’s thermostat√解析：(5).Which of the following statements are the supporters of “Earth’s plan B” for? （分数：1.00）A.It’s Time to Go GreenB.Energy-efficient measures must be taken √C.Mass migration to the poles is inevitableD.For the Planet’s Geoengineer or Catatrophe解析：Passage Five Brittany Donovan was born 13 years ago in Pennsylvania. Her biological father was sperm donor G738. Unbeknownst to Brittany’s m other, G738 carried a genetic defect known as fragile X-a mutation that all female children born from his sperm will inherit, and which causes mental impairment, behavioral problems and atypical social development. Last week, Brittany was given the green l ight to sue the sperm bank, Idant Laboratories of New York, under the state’s product liability laws. These laws were designed to allow consumers to seek compensation from companies whose products are defective and cause harm. Nobody expected them to be applied to donor sperm.Thousands of people in the US have purchased sperm from sperm banks on the promise that the donor’s history has been carefully scrutinized and his sample rigorously tested, only for some of them to discover that they have been sold a batch of bad seed. Some parents learn about genetic anomalies after their disabled child is born and they press the sperm bank for more information. Others realize it when they contact biological half-siblings who have the same disorder. So will Donovan vs Idant laboratories open the floodgates? It seems unlikely. New York’s product liability laws are highly unusual in that they consider donor sperm to be a product just like any other. Most other US states grant special status to blood products and body parts, including sperm. In these states, donor sperm is not considered a “product” in the usual sense, despite the fact that it is tested, processed, packaged, catalogued, marketed and sold. Similarly, European Union product liability law could not be used in this way. Even if this lawsuit is an isolated case, it still raises some difficult questions. First, to what lengths should sperm banks go to ensure they are supplying defect-free sperm? As we learn more and more about human genetics, there is growing list of tests that could be performed. Nobody would deny that donor sperm carrying the fragile X mutation should be screened out--- and there is a test that can do so ---but what about more subtle defects, such as language impairment or susceptibility to earl y Alzheimer’s? Donovan vs Idant Laboratories also serves as a reminder of the nature of the trade in human gametes. Sperm bank catalogues can give the impression that babies are as guaranteed as dishwashers. The Donovans are entitled to their day in court, but in allowing the product liability laws to be used in this way, the legal system is not doing much to dispel that notion. （分数：5.00）(1).Donovan sued Idant Laboratories for ______________. （分数：1.00）A.a cheat in boasting its biological productsB.donor sperm as a productC.problematic donor sperm √D.a breach of confidentiality解析：(2).It can be inferred from the passage that thousands of people in the US purchase sperm_____________. （分数：1.00）A.without knowing its potential dangers √B.regardless of repeated warningsC.for the reason of quality supplyD.for their desperate needs解析：(3).The question from the case is whether ___________. （分数：1.00）A.people are entitled to donor spermB.donated sperm should be just a product √C.Donovan is allowed to sue the sperm bankD.Donovan’s health problems have been clinically certified解析：(4).It seems that sperm banks are in no position to _______________. （分数：1.00）A.treat donor sperm as a productB.screen out the fragile X mutationC.manage their business as others do in NYD.guarantee sperm absolutely free of any defect √解析：(5).The statement Sperm bank catalogues can give the impression that babies are as guaranteed as dishwashers implies that _____________. （分数：1.00）A.Donovan will surely win the case in courtB.any product could have a defect in one way or another。
南京医科大学生物化学与分子生物学(专业基础课)2008,2010--2016年考博真题
二、问答题（2×20分=40分）
1.肝在代谢中的作用？简述红细胞、心、脑和脂肪代谢的特点。
2.胰高血糖素调节血糖的信号转导机制。
南京医科大学
2016年攻读博士学位研究生入学考试试题
考试科目：生物化学与分子生物学（专业基础课）
注意：所有答案一律写在答题纸上，写在试题纸上或其他地方一律不给分。
注意：所有答案一律写在答题纸上，写在试题纸上或其他地方一律不给分。
一、简答题（6×10分=60分）
1.举例说明酶在疾病发生、诊断和治疗中的作用和机制。
2.血浆中脂蛋白的分类和作用。
3.动物体内主要的RNA种类和作用，什么叫非编码RNA。
4.什么是血氨，其来源，去路和转运？
5.半保留复制的定义，复制与转录的异同。
一、简答题
1.联系呼吸链解释CO中毒致死原因
2.以肾上腺素为例解释膜受体的激素信号转导
3.血氨来源去路及运输方式
4.DNA变性和蛋白变性
5.酶原及酶原激活
6.miRNA siRNA定义
7.哪些酶，蛋白质因子参与了DNA合成，以及它们的功能
8.糖，脂，蛋白质三大物质之间的相互转换，说明为什么？
南京医科大学
一、简答题（5×12=60分）
1.什么是非编码RNA，简述其分类及功能。
2.什么是蛋白质变性，列举有哪些方法并说明一项用途。
3.乳糖调控子的结构及作用机制。
4.氧化磷酸化的调节因素。
5.简述维生素B的两项功能。
二、问答题（2×20=40分）
1.什么是基因治疗，什么是基因诊断。阐述基因治疗的策略。
2.肝功受损后哪些物质代谢途径受影响？阐述原因。
二、问答题：
2013博士生招生考试考题
分子生物学1．把下列20个名词或短语分别填写在下表B列各行空格中，使其与A列同一行的名词或短语匹配：（20分）(1) β折叠层(2) cGMP (3) 锌指蛋白(4) 简并性(5) 顺反子(6) 5-溴尿嘧啶(7) 肽键形成(8) 转录因子识别(9)解除DNA正超螺旋(10)非放射性标记(11) DNA结合域(12) 反向重复序列(13) α因子结合的DNA序列(14) 电子传递链(15) 简单重复序列(16) 跨损伤合成2．判断是非，不改错（20分）。
(1)紫外线照射可引起DNA两条互补链上的T碱基之间形成嘧啶二聚体。
(2)药物利福平阻断RNA聚合酶与启动子部位的结合来抑制mRNA合成的起始。
(3)真核生物的所有mRNA都含有poly(A)结构。
(4)多顺反子mRNA含有多个起始密码子和终止密码子。
(5)所有氨基酸都各自有其对应的遗传密码子。
(6)cDNA克隆较基因组克隆最大的优越性在于更容易获得基因的完整序列。
(7)硝酸纤维素膜和尼龙膜都可作为电转移DNA的支持物。
(8)阿拉伯糖操纵子也是可诱导的，阿拉伯糖本身就是诱导物。
(9)真核生物基因的活跃转录是在常染色质上进行的。
(10)DNA甲基化能诱导真核生物基因的重新活化，去甲基化则关闭某些基因的活性。
(11)真核生物rRNA的化学修饰主要是核糖位置的磷酸化修饰。
(12)正超螺旋DNA可被拓扑异构酶转换成非超螺旋DNA。
(13)真核生物有引发酶与DNA聚合酶δ结合。
(14)如果一个基因在雌性中而不在雄性中被标记以“印记”，则该印记基因可在雄性中表达。
(15)某些前rRNA分子也含有tRNA分子。
(16)微生物对抗生素的抗性是选择性突变。
(17)碱基替换可引起移码突变。
(18)插入试剂主要引起转换和颠换。
(19)溶原体就是含有原噬菌体的细胞。
(20)通过削弱DNA分子中两个相对的骨架之间内在的排斥力，高盐浓度减少了杂交反应的严格性。
3．选择题。
（从每小题后的4项备选中，选择最适合的1项，回答问题，或者填空。
2013年全国医学博士英语统一考试真题
2013年全国医学博士英语统一考试真题全文共6篇示例，供读者参考篇1The Big Grown-Up TestHi there! My name is Lily and I'm 8 years old. I'm going to tell you all about this really big test that happened a few years ago. It was called the 2013 National Unified English Exam for Medical Doctoral Students. That's a really long name, isn't it? I'll just call it the Big Grown-Up Test.I didn't actually take the test myself because I'm just a kid. But my mom is a doctor and she had to take a test kind of like it when she was in medical school a long time ago. She said it was super hard and made her really nervous! The Big Grown-Up Test was only for the really smart adults who wanted to get their "doctoral" degree, which is like the highest level of education you can get.From what I understand, the test happened all across China on the same day. Thousands of grown-ups had to go to test centers and take it. Can you imagine having to sit still and take ahuge test for hours and hours? I don't think I could do that. I'd get way too antsy!The test had four main sections - listening, reading, writing, and speaking. For the listening part, the grown-ups had to listen to recordings and answer questions about what they heard. In the reading section, they had to read really long, complicated passages and answer questions proving they understood everything.But here's the crazy part - the whole test was in English! And not just simple English either. We're talking medical English with all those big fancy words that I can't even pronounce. My mom showed me a practice test once and I couldn't understand a word of it. Just a bunch of mumbo-jumbo if you ask me!For the writing section, the grown-ups had to write an essay or paper about some scientific topic. They couldn't just write "The cat ran after the bird" type stuff. They had to use their best English and fanciest words to discuss complex ideas. No "See Spot run" for these over-achievers!Then for the speaking portion, they had to actually talk out loud and have conversations in English about different medical scenarios. They were graded on their vocabulary, pronunciation, and how well they could explain things. If they slipped up andaccidentally spoke Chinese, it was an automatic fail! That's so much pressure.From what my mom told me, everyone taking the Big Grown-Up Test had studied English for years and years. They took special classes and worked really hard to prepare. But even then, the test was still incredibly difficult. I guess that's why they call it the "doctoral" level. Only the best of the best could pass!My mom said the listening section was the hardest part for her because you only get to hear things once. If you zone out for even a second, you're totally lost. And with all those crazy medical terms being fired at you rapid-fire, it was really easy to miss important details. She had to practice listening exercises every single day to get ready.The reading section was also a killer because the passages were just sooooooo long and dry. My mom showed me one that was 20 pages about the molecular biology of cancer. BO-RING! She said you had to be able to skim for key information really quickly but also understand every little detail. It took crazy focus.For the writing section, my mom's biggest challenge was making sure she used proper academic style. You couldn't just write normally like a letter to your friend. It had to be formal"scholarly" English with a clear and logical structure. No slang or contractions allowed!And then speaking English out loud without stumbling over vocabulary? My mom said that part made her want to cry. You had to be able to think and speak at the same time without any awkward pauses. One little "umm" and you could blow the whole thing. She practiced having fake doctor-patient conversations with her English tutor every week. Talk about nerve-wracking!Even though my mom studied so hard, she was still a nervous wreck before the Big Grown-Up Test. She stayed up late every night for weeks going over practice questions. The day of the test, she barely slept at all. I remember her pacing around the apartment that morning, muttering English words under her breath like "hematology...nephrology...gastroenterology." I thought she was going crazy!When she finally came home after the marathon test session, she looked like a zombie. She plopped down on the couch, completely drained from using her brain so much. All she could do was stare at the wall. But you know what? A few months later, she found out she passed! We had a huge family celebration. All that hard work had paid off.After hearing how brutal the Big Grown-Up Test was, I have even more respect for doctors like my mom. Can you imagine having to prove your medical knowledge IN ENGLISH at that level? With listening, reading, writing, speaking...the whole shebang? It's amazing that anyone can do it! I guess that's why kids can't just become doctors. You have to be one smart and determined grown-up.Well, that's the story of the 2013 National Unified English Exam for Medical Doctoral Students in China. It was basically a mental marathon testing the English skills of the cream of the crop. I don't know about you, but I'm staying far away from any exams that extreme! Give me some simple addition and subtraction any day. I'll leave those crazy Big Grown-Up Tests to the adults. Let me know if you ever want to hear about the "iguanas of the Galapagos" or something equally riveting like that killer medical exam. I'll keep my stories kid-friendly!篇2The 2013 Doctor TestHey guys! Today I'm going to tell you all about this really hard test that medical students have to take. It's called the 2013National Unified English Test for Medical Doctoral Students. That's a huge name for a test!My older sister Sarah is studying to be a doctor. She had to take this big important test last year. I watched her study for it and it looked super duper hard. There was a ton of big medical words I couldn't even pronounce!Sarah said the test had four different sections. The first part was listening. They played audio recordings and asked questions to see if you understood what you heard. My sister practices this by watching English TV shows and movies without subtitles. She said practicing listening is really important for talking to patients someday.The next section was reading. You had to read a bunch of different passages and articles and answer comprehension questions. Sarah read giant medical textbooks to get ready. The readings were probably really boring unless you're realllly into that doctor stuff.After that was the writing section. You had to write essays and reports based on pictures or prompts they gave you. Sarah practiced writing samples all the time. I helped her check for mistakes sometimes but a lot of it was way over my head!The final part was speaking. You had to record yourself answering questions and explaining things out loud. It tests if you can communicate well in English. Sarah set up a video camera and recorded herself talking for hours to get ready. I'm glad I didn't have to listen to all that practice!Overall it sounded like the toughest test ever. Sarah studied non-stop for months beforehand. She said it was crucial to do well since getting a high score can help you get into better medical programs and jobs after graduating.The test was administered on paper at testing centers across the country. Maybe thousands of students took it at the same time? I can't even imagine having to take a test that massive and important. No thank you!When Sarah finally took the real test, she was sooo nervous. But she felt prepared after all her hard work studying. She had to travel to the closest testing site which was a few hours away from our house. Can you believe she had to take the whole 4-hour test in just one sitting? No breaks! I don't know how she stayed focused that long.I'm telling you, this 2013 Unified English Test was no joke. Just listening to Sarah talk about it gave me anxiety! The test covered every little detail of medical communication in English. Itreally separated the students who were proficient in English from those who weren't quite there yet.After what felt like an eternity, Sarah got her score report in the mail. She passed with flying colors! We were all so proud and relieved for her. First she celebrated by going out for a huge ice cream sundae. She deserved It after that monster of a test!Apparently Sarah's high score will allow her to apply to lots of competitive medical residency programs after she finishes regular doctor school. That's really good news since those programs are super exclusive and tough to get into. All thanks to nailing the 2013 National English Test!Phew, I'm exhausted just from talking about this test! I'm definitely not cut out to be a doctor. I'll stick to cartoons and video games for now. But I'm really proud of my amazing big sis Sarah for powering through that incredibly difficult English exam. After hearing how intense it was, I have a whole new respect for doctors and medical students.Well, that's my extremely detailed and passionate summary of the 2013 National Unified English Test for you all! I hope I did a good job explaining it from a kid's point of view. Let me know if you have any other questions! Time for a snack break...篇3The Big Scary Test DayWow, today was a really big day! I had to wake up super early because my mom and dad said I had to take a really important test. They called it the "2013 National English Test for Medical Doctoral Students." That's a really long name for a test! I don't even know what a "doctoral student" is.When we got to the testing place, there were so many grown-ups there. I felt like a tiny little kid in a sea of giants! The room was huge, and there were desks set up everywhere. My mom pointed to a desk near the front and told me that was going to be my spot for the test. I was really nervous!The test proctor lady came in and started explaining all the rules. She said we couldn't talk, couldn't look at each other's papers, and had to keep our eyes on our own test booklets. It sounded really strict! I got even more nervous thinking about how I wasn't allowed to ask any questions during the test.Finally, the proctor said it was time to begin. She passed out the test booklets, and they were super thick! My booklet had to be at least 100 pages long. I gulped and thought to myself, "How am I ever going to finish this whole thing?"The first section was listening comprehension. The audio started playing, and a friendly-sounding lady's voice came through the speakers. She was talking about something called "medical ethics." I had no idea what that meant, but I tried my best to listen carefully and answer the questions.Next up was the reading section. The passages were all about science and medical stuff. There were so many big words that I didn't understand! I just tried to read slowly and carefully, and answer the questions to the best of my ability.After what felt like forever, we finally got to take a short break. I stretched my legs and used the bathroom. My brain felt like mush from trying so hard to concentrate.The writing section was probably the hardest part for me. We had to write a whole essay about some complicated medical topic. I did my best to string some sentences together, but I'm not sure if it made any sense. Writing is hard!The very last section was speaking. We had to goone-by-one into a different room and answer some questions out loud while a lady recorded us on a computer. I was so nervous that my hands were shaking! But the lady gave me an encouraging smile, and I tried my best to speak slowly and clearly.At long last, the whole test was finally over! My brain felt like a big jumbled mess, but I was so relieved that it was done. All the grown-ups were packing up their things and getting ready to leave. I found my mom and dad, and they gave me a big hug and told me they were proud of me for working so hard.On the way home in the car, I fell into a deep sleep. Taking that medical doctoral test was the most difficult thing I've ever done in my whole life! I sure hope I did okay on it. But either way, I'm just glad it's over. Phew, what a day!篇4Hi there! My name is Timmy and I'm 8 years old. Mrs. Thompson asked me to write about my experience taking the 2013 National Medical Doctoral English Unified Exam. I know it sounds really hard for a kid like me, but I'll do my best to explain it!It all started a few weeks ago when my big sister Susie came home from medical school. She looked really stressed out. When I asked her what was wrong, she told me she had to take this huge exam called the "National Medical Doctoral English Unified Exam." It's a test that all medical students have to pass before they can become real doctors.Susie said the exam was going to be super duper hard because it's all in English. English is like a foreign language to her since we only speak Chinese at home. She had to learn all sorts of big fancy medical words in English. Just thinking about it made my head hurt!Anyway, Susie had to study day and night to get ready. Our house was covered in medical textbooks, flashcards, and empty coffee mugs. I tried to help her study, but I could barely even read the words, let alone understand what they meant!Finally, the day of the big exam arrived. Susie was so nervous, she barely ate any breakfast. I gave her a high-five for good luck as she headed out the door. "You've got this, sis!" I shouted. She just grimaced and kept walking.The exam was held at a huge testing center downtown. There were hundreds of students there, all looking just as stressed as Susie. The rules were super strict - no talking, no cheating, and definitely no bathroom breaks! I'm glad I wasn't the one taking it.Susie said the first part was listening comprehension. She had to listen to doctors giving instructions and answer questions about what they said. Next up was reading comprehension about different medical cases and procedures. Susie told mesome of the words were so long and confusing, she wanted to cry!After that was the writing section where she had to explain medical concepts in clear English. Susie's hand cramped up from writing so much. Then there were all sorts of other sections testing grammar, vocabulary, speaking ability, you name it!The exam lasted over 6 hours. SIX HOURS! I can't even sit still for that long when I'm watching cartoons. Susie looked exhausted when she finally emerged from the test center. Her face was pale and she could barely speak from using so much brainpower.I gave her a big celebratory hug when she got home. She plopped down on the couch and didn't move for like three hours. Mom made her favorite dumplings for dinner to congratulate her on surviving the epic exam day.A few weeks later, the results came in the mail. Susie passed!! She got high enough scores to start her medical residency. I was super proud of her for proving she was smart enough to be a doctor, even in English.In the end, Susie said the exam was one of the hardest things she'd ever done in her entire life. But she was also really glad shepushed herself and worked so hard to achieve her dream career. Seeing my big sis overcome that huge challenge inspired me to never give up, no matter how difficult things get.Who knows, maybe one day I'll be the one taking the crazy Medical Doctoral English Exam? Although I'll probably need to learn English first before I can think about becoming a doctor. Baby steps!Well, that's my tale of the legendary 2013 medical exam. I hope I explained it okay! Let me know if you need me to dumb it down even more. Writing at an 8-year-old level is harder than it looks. Now if you'll excuse me, I have an important kindergarten final coming up on finger painting...篇5My Trip to the DoctorHi! My name is Lily and I'm 8 years old. Today I'm going to tell you all about my trip to the doctor last week. It was a really exciting adventure!It all started on Monday morning. I woke up and my throat was super sore and scratchy. I could barely swallow without it hurting. "Uh oh," I thought, "I must be getting sick."I went to the kitchen where my mom was making breakfast. "Good morning sweetie," she said in a cheery voice. "Are you ready for another fun day at school?"I shook my head sadly. "No mom, my throat really hurts," I croaked out in a raspy voice. I stuck out my bright red, swollen tonsils for her to see.My mom's eyes got really wide. "Oh no, you poor thing!" she exclaimed. "That looks like a nasty case of tonsillitis. I better call the pediatrician right away to get you an appointment."The pediatrician is just a fancy word for a kids' doctor. My mom dialed their number and talked on the phone for a few minutes. When she hung up, she looked at me with a sympathetic smile."Okay sweetie, I was able to get you in to see Dr. Stevens this afternoon at 3 o'clock. In the meantime, I want you to go rest on the couch and I'll bring you some warm tea with honey to soothe your throat."I nodded listlessly and shuffled over to the living room couch, wrapping myself up in a fuzzy blanket. My mom brought me the tea a little later and I sipped it slowly, relieved by the smoothing sensation on my poor, abused throat.A few hours later, it was time to head to the doctor's office. We loaded into our blue minivan and off we went! I had visited Dr. Stevens many times before, so I knew the way to her office like the back of my hand.When we arrived, my mom checked me in at the front desk. "Lily Anderson to see Dr. Stevens for a 3 o'clock sick visit," she told the friendly receptionist. We only had to wait about 10 minutes before a nurse opened the door to the hallway."Lily Anderson?" she called out in a singsong voice. I perked up, time for the real fun to begin! We followed the nurse down the hallway lined with colorful drawings by kids. She brought us into the examination room and checked my temperature, blood pressure, and other vitals."The doctor will be right in," she told us before leaving the room. My mom and I had to wait just a couple of minutes before there was a knock at the door."Hello there!" the cheery voice of Dr. Stevens called out as she entered. "What seems to be the trouble today?""Lily has a really bad sore throat, I'm afraid she may have tonsillitis," my mom explained while I just nodded weakly.Dr. Stevens had me open my mouth wide and say "Ahhhh" while she inspected my crimson tonsils with a tongue depressor. She also felt around my neck checking for swollen lymph nodes."You're absolutely right, those tonsils are very inflamed and swollen," Dr. Stevens declared with a frown. "And I can feel her lymph nodes up as well. This is definitely a case of acute tonsillitis, most likely caused by a bacterial infection."My heart sank - bacterial infection sounded really serious and scary! I started to whimper but my mom gave my hand a reassuring squeeze."Not to worry Lily," Dr. Stevens said with a kind smile, "we'll have you feeling good as new in no time. I'm going to prescribe a course of antibiotics to get rid of that nasty tonsillitis."The antibiotics would be special medicine that I'd have to take for about 10 days to kill the bacterial infection making me sick. Dr. Stevens called the prescription into my regular pharmacy and told my mom I should start feeling better in a day or two once the antibiotics kicked in.As we left the office, I felt a huge wave of relief wash over me. Taking some occasional gross-tasting medicine was no big deal if it meant I would stop feeling so miserable! Sure enough, after acouple days of the antibiotics, the swelling in my throat had gone down dramatically and I was on the road to recovery.I was so thankful my mom took me to see Dr. Stevens right away. Tonsillitis sounds like no fun at all if you let it go untreated! From now on, if my throat ever starts feeling funny again, you can be sure I'll let my parents know immediately. Staying on top of your health is very important, even for kids. Getting check-ups and taking care of any issues right away is the key to staying healthy and happy!Well, that's the full scoop on my exciting trip to the doctor. Wasn't it a wild ride? I can't wait for my next doctor's visit adventure - I hear the lollipops they give out are the best! Thanks for reading, friends!篇6The 2013 Doctor English Test Was Really Hard!Hi everyone! My name is Timmy and I'm 8 years old. I really struggled with the 2013 national medical doctoral English unified exam this year. It was super duper difficult! I had to wake up at 6am to get to the test center by 8am. The test was scheduled from 8:30am to 5pm with just a short lunch break.That's a really long time for a kid to have to sit still and concentrate!The test had four sections - listening, reading, writing, and speaking. The listening section was first. We had to wear headphones and listen to conversations, lectures, and talks. Then we had to answer multiple choice questions about the main ideas, details, speaker's purposes, and making inferences. It was hard to pay attention the whole time without getting distracted!After listening, we moved right into the reading section. This part had really long and boring passages to read through. The passages were about all kinds of topics like science, history, culture, and academics. Some of the words were so advanced that I had never even heard them before! The questions asked about the main ideas, details, vocabulary, making inferences, and the author's views and purposes. My eyes started getting tired from all that reading.We then got a short lunch break, which was a nice break to rest my brain. But after lunch came the terrible writing section! We had to write two essays of different types, like an argument essay or a proposal essay. The prompt topics were really complex subjects that I didn't know much about. It was so hard to organize my thoughts and come up with enough supportingideas and examples to write a whole essay! My hand cramped up from all that writing.Finally after writing came the absolute worst part - the speaking section! We had to give spoken responses into a microphone about random topics and scenarios. I get so nervous speaking English out loud! We had to speak for 1-2 minutes on each question, using great vocabulary and organization. My mind just went blank under all that pressure. By the end, my mouth was dry from talking so much.This test was crazy difficult, way harder than anything we do in my regular English classes at school. I really hope I passed and don't have to take it again next year! I could barely stay awake driving home after the 9 hour exam. My brain felt like mush!Tests like this medical doctoral English exam seem way too hard for a little kid like me. How are adults even supposed to get through something so grueling and intense? Just thinking about it again makes me tired! I'll be happy if I never have to take another big standardized English exam for the rest of my life. No more essays, listening exercises, or speaking into microphones for me - I'm sticking to kids stuff from now on!。
2013医学考博试题1
2013医学考博试题12013南京医科大学细胞生物学（专业基础）考博真题回忆版1、什么是端粒酶？有什么特点，请简述端粒酶的表达水平与细胞增殖的关系2、什么是蛋白质的分选？及影响其分选的关键因素是什么？3、主动运输与被动运输的特点4、简述胚胎干细胞、终端分化细胞核癌细胞的生长和分化特点5、从细胞分化角度说明多利羊诞生的启示6、个体低密度脂蛋白（LDL）受体缺失引起高胆固醇血症的原理7、大题一（20分）：什么是细胞周期蛋白，有几类，各有什么功能，举例说明8、大题二（20分）：什么是细胞凋亡？有何特点？举例说明细胞凋亡的检测方法及其原理南京医科大学生物化学与分子生物学（我考的A卷）一、简答题（6X10分）1、酶活性调节的方式和机理2、什么是TCA循环，为什么TCA循环是三大物质代谢的枢纽3、什么是尿素循环，及其生理和病理意义4、什么是操纵子，乳糖操纵子的结构和正负性调节的机理5、什么是第二信使，举例说明第二信使如何参与信号转导通路6、转录与复制的异同二、问答题（2x20分）1、举例说明蛋白质构象改变与功能的关系2、写出至少6种RNA的名称，并简述其结构特点和功能南京医科大学老年医学一.简答题（6X10分）1.肠结核的诊断线索2.何谓肾上腺危象3.何谓DKA4.主动脉夹层的分型和临床表现5.中晚期食管癌的临床表现6.支气管哮喘的诊断标准二.问答题（2X20）1.原发性高血压的预后判断2.什么是肺血栓栓塞症，及其临床表现和诊断依据南京医科大学2013年药理学博士试题一、简答题（6×10）1、评价药物效应的指标有哪些？2、肾上腺素受体的分离及其临床应用？3、心律失常药的分类，代表药物及作用机制？、4、抗哮喘药物的分类及机制？5、糖皮质激素的临床应用及不良反应？6、简述怎样合理应用抗生素？二、论述题（任选两题，2×20）1、药物不良反应的类型，药物代谢酶对药物不良反应的影响？2、强心苷的临床应用，与ACEI相比有何优点？、3、中枢多巴胺紊乱所导致的疾病及其应对策略？4、抗肿瘤药物的分类及其机制？南京医科大学2013年生理学博士试题一、简答题（6×10）1、细胞兴奋后其兴奋性如何变化？与各期动作电位有何对应关系？2、什么是中心静脉压？其影响因素及临床意义？3、简述氧离曲线的影响因素？4、胃排空的过程及其影响因素？5、比较兴奋性突触传递及抑制性突触传递过程的异同？6、长期饮食缺乏碘为什么会引起甲状腺肿大？二、问答题（2×20）1、糖皮质激素的作用及其调节？2、兴奋交感神经对心肌细胞生理特性有什么影响，并设计实验加以证明。
遗传学考试试题库(汇总)(含答案解析)
第一章绪论一、名词解释遗传学：研究生物遗传与变异的科学。
变异（variation）：指亲代与子代以及子代各个个体之间总是存在不同程度的差异有时子代甚至产生与亲代完全不同形状表现的现象。
遗传(heredity)：指在生物繁殖过程中，亲代与子代以及子代各个体之间在各方面相似的现象。
二、填空题在遗传学的发展过程中，Lamarck提出了器官的用进废退和获得性遗传等学说；达尔文发表了着名的物种起源，提1892年提出了种质学说，认为生物体是由体质和种质两部分组成的；孟德尔于1866，认为性状的遗传是由遗传因子控制的，并提出了遗传因子的分离和自由组合定律；摩尔根以果蝇为材料，确定了基因的连锁程度，创立了基因学说。
沃特森和克里克提出了着名的DNA分子双螺旋结构模式，揭开了分子遗传学的序幕。
遗传和变异以及自然选择是形成物种的三大因素。
三、选择题1、被遗传学家作为研究对象的理想生物，应具有哪些特征以下选项中属于这些特征的有：( D )A.相对较短的生命周期B.种群中的各个个体的遗传差异较大C.每次交配产生大量的子代D.以上均是理想的特征2、最早根据杂交实验的结果建立起遗传学基本原理的科学家是：( )A James D. WatsonB Barbara McClintockC AristotleD Gregor Mendel3、以下几种真核生物，遗传学家已广泛研究的包括：( )A 酵母B 果蝇C 玉米D 以上选项均是4、根据红色面包霉的研究，提出“一个基因一种酶”理论的科学家是：（）A Avery O. TB Barbara McClintockC Beadle G. WD Gregor Mendel三、简答题如何辩证的理解遗传和变异的关系遗传与变异是对立统一的关系：遗传是相对的、保守的；变异是绝对的、发展的；遗传保持物种的相对稳定性，变异是生物进化产生新性状的源泉，是动植物新品种选育的物质基础；遗传和变异都有与环境具有不可分割的关系。
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二、问答题
1、基因治疗的概念，步骤，及存在的问题。
2、人类基因组计划取得了哪些成果，未来会在医学方面有哪些成就。
考
博
真
题
南京医科大学
2013年攻读博士学位研究生入学考试试题
考试科目：遗传学
注意：所有答案一律写在答题纸上，写在试题纸上或其他地方一律不给分。
一、简答题
1、遗传病的概念及特点。
2、Lyon假说的内容。
3、表观遗传学的概念，举例说明表观遗传学与疾病的关系。
4、多基因遗传病的概念，怎样评估再发。
5、遗传学平衡定律，及其影响因素。