中药三联疗法对慢性盆腔炎血清炎性指标及血液流变学的影响
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Effect of Chinese Medicine Triple Therapy on Serum Inflammatory Markers and Hemorheology in Patients with Chronic Pelvic Inflammatory Disease
WU Fei-hua Department of gynaecology, Jiangxi Provincial Hospital of traditional Chinese medicine, Nanchang Jiangxi 330006,China [Abstract] Objective: To investigate the effect of TCM triple therapy on serum inflammatory indexes and hemorheology of chronic pelvic inflammatory disease, and guide the clinical application. Methods: 124 patients with chronic pelvic inflammation selected from March 2016 to March 2018 in our hospital were divided into western medicine group and traditional Chinese medicine group according to the principle of random grouping. The western medicine group was given Cefradine capsule orally + microwave irradiation physiotherapy + tinidazole injection enema triple therapy, while the traditional Chinese medicine group was given traditional Chinese medicine plus Chinese medicine hot compress and Chinese medicine enema triple therapy. Results: After treatment, the levels of TNF-a, CRP, IL-1beta and IL-6 in western medicine group and Chinese medicine group were significantly lower than those before treatment (P<0.05). After treatment, the levels of TNF-a, CRP, IL-1beta and IL-6 in Chinese medicine group were significantly lower than those in western medicine group (P<0.05). The erythrocyte sedimentation rate, whole blood high shear viscosity and whole blood low shear viscosity were significantly lower than those before treatment (P<0.05). After treatment, the hematocrit, erythrocyte sedimentation rate, whole blood high shear viscosity and whole blood low shear viscosity in TCM group were significantly lower than those in western medicine group (P<0.05). Conclusion: TCM triple therapy can effectively improve the hemorheological indexes of patients with chronic pelvic inflammatory disease, alleviate the inflammatory reaction of patients, and increase the clinical value. [Key words] Chinese medicine Orally; Chinese Medicine hot Compress; Chinese Medicine Enema; Chronic Pelvic Inflammation; Inflammatory Indicators; Hemorheology
药物与慢性盆腔炎血清炎性指标及血液流变学
的影响
吴飞华 江西省中医院中医妇科，江西 南昌 330006 [摘要] 目的：探讨中药三联疗法对慢性盆腔炎血清炎性指标及血液流变学的影响，进而指导临床应用。方法：选取我院2016年3月—2018 年3月收治的慢性盆腔炎患者124例，所有患者按照数字随机分组原则分为西药组和中药组各62例，西药组患者给予头孢拉定胶囊口服+微 波照射物理治疗+替硝唑注射液灌肠三联疗法，中药组患者给予中药口服+中药热敷+中药灌肠三联疗法。结果：治疗后，西药组和中药组 TNF-a、CRP、IL-1β以及IL-6均明显下降，与治疗前比较，差异显著(P<0.05)；治疗后，中药组TNF-a、CRP、IL-1β以及IL-6均明显低于 西药组，差异显著(P<0.05)；治疗后，西药组和中药组血细胞比容、红细胞沉降率、全血高切黏度以及全血低切黏度均明显下降，与治疗 前比较，差异显著(P<0.05)；治疗后，中药组血细胞比容、红细胞沉降率、全血高切黏度以及全血低切黏度均明显低于西药组，差异显著 (P<0.05)。结论：中药三联疗法可有效改善慢性盆腔炎患者血液流变学指标，缓解患者的炎性反应，临床应用价值较高。 [关键词] 中药内服；中药热敷；中药灌肠；慢性盆腔炎；炎性指标；血液流变学 [中图分类号] R271.1 [文献标识码] A [文章编号] 1672-2809(2018)20-0052-04
WU Fei-hua Department of gynaecology, Jiangxi Provincial Hospital of traditional Chinese medicine, Nanchang Jiangxi 330006,China [Abstract] Objective: To investigate the effect of TCM triple therapy on serum inflammatory indexes and hemorheology of chronic pelvic inflammatory disease, and guide the clinical application. Methods: 124 patients with chronic pelvic inflammation selected from March 2016 to March 2018 in our hospital were divided into western medicine group and traditional Chinese medicine group according to the principle of random grouping. The western medicine group was given Cefradine capsule orally + microwave irradiation physiotherapy + tinidazole injection enema triple therapy, while the traditional Chinese medicine group was given traditional Chinese medicine plus Chinese medicine hot compress and Chinese medicine enema triple therapy. Results: After treatment, the levels of TNF-a, CRP, IL-1beta and IL-6 in western medicine group and Chinese medicine group were significantly lower than those before treatment (P<0.05). After treatment, the levels of TNF-a, CRP, IL-1beta and IL-6 in Chinese medicine group were significantly lower than those in western medicine group (P<0.05). The erythrocyte sedimentation rate, whole blood high shear viscosity and whole blood low shear viscosity were significantly lower than those before treatment (P<0.05). After treatment, the hematocrit, erythrocyte sedimentation rate, whole blood high shear viscosity and whole blood low shear viscosity in TCM group were significantly lower than those in western medicine group (P<0.05). Conclusion: TCM triple therapy can effectively improve the hemorheological indexes of patients with chronic pelvic inflammatory disease, alleviate the inflammatory reaction of patients, and increase the clinical value. [Key words] Chinese medicine Orally; Chinese Medicine hot Compress; Chinese Medicine Enema; Chronic Pelvic Inflammation; Inflammatory Indicators; Hemorheology
药物与慢性盆腔炎血清炎性指标及血液流变学
的影响
吴飞华 江西省中医院中医妇科，江西 南昌 330006 [摘要] 目的：探讨中药三联疗法对慢性盆腔炎血清炎性指标及血液流变学的影响，进而指导临床应用。方法：选取我院2016年3月—2018 年3月收治的慢性盆腔炎患者124例，所有患者按照数字随机分组原则分为西药组和中药组各62例，西药组患者给予头孢拉定胶囊口服+微 波照射物理治疗+替硝唑注射液灌肠三联疗法，中药组患者给予中药口服+中药热敷+中药灌肠三联疗法。结果：治疗后，西药组和中药组 TNF-a、CRP、IL-1β以及IL-6均明显下降，与治疗前比较，差异显著(P<0.05)；治疗后，中药组TNF-a、CRP、IL-1β以及IL-6均明显低于 西药组，差异显著(P<0.05)；治疗后，西药组和中药组血细胞比容、红细胞沉降率、全血高切黏度以及全血低切黏度均明显下降，与治疗 前比较，差异显著(P<0.05)；治疗后，中药组血细胞比容、红细胞沉降率、全血高切黏度以及全血低切黏度均明显低于西药组，差异显著 (P<0.05)。结论：中药三联疗法可有效改善慢性盆腔炎患者血液流变学指标，缓解患者的炎性反应，临床应用价值较高。 [关键词] 中药内服；中药热敷；中药灌肠；慢性盆腔炎；炎性指标；血液流变学 [中图分类号] R271.1 [文献标识码] A [文章编号] 1672-2809(2018)20-0052-04