不同年龄2 型糖尿病患者心血管疾病的风险性预测
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【关键词】 心血管疾病 ；青年 2 型糖尿病 ；横断面研究
Cardiovascular disease risk profiles in type 2 diabetic patients with different ages Yuan Congru, Dong Shuanghua, Huangfu Xiaoyan. Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China Corresponding author: Hangfu Xiaoyan, Email: dui502532@
【Abstract】 Objective To compare the risk of cardiovascular disease (CVD) in young and elderly type 2 diabetes. Methods The study population were derived from Affiliated Hospital of Inner Mongolia medical university from January 1, 2013 to January 1, 2014. A systematic sampling method was used to select 924 patients with type 2 diabetes, of which 485 were young patients (18-40 years old), 439 were elderly patients (>60 years old). Referring to the CVD risk assessment measurement model, cross-sectional study was used to compare the CVD factors such as hypertension, obesity[body mass index (BMI) >25 kg/m2], hyperglycemia and hypercholesterolemia in the patients. The follow-up continued to January 1, 2019, and the risk of CVD in both groups was observed. Results There was no statistically significant difference in glycosylated hemoglobin (HbA1c), BMI, systolic blood pressure, diastolic blood pressure, total cholesterol, and low-density lipoprotein between young and elderly patients with type 2 diabetes (P > 0.05). There was also no statistically significant difference in CVD risk factors including hypertension, obesity, hyperglycemia and hypercholesteremia (P > 0.05). Furthermore, there were no statistically significant differences of cumulative proportion in zero CVD risk factor, one risk factor, two risk factors, three risk factors, and four risk factors in young and elderly patients with type 2 diabetes (P > 0.05). There were no statistically significant differences in CVD cases at the end of follow-up time, CVD cases of follow up for five years, two CVD cases, and two or more CVD cases between the two groups (P > 0.05). Conclusion The risk of CVD in young patients with type 2 diabetes is not lower than that in elderly patients.
· 352 ·
心脑血管病防治 2020 年 8 月第 20 卷第 4 期 Cardio-Cerebrovasc Dis Prev Treat,August 2020,Vol.20,No.4
论著
不同年龄 2 型糖尿病患者心血管疾病的风 险性预测
苑丛茹 董双华 皇甫晓燕
【摘要】 目的 比较青年与老年 2 型糖尿病心血管疾病（CVD）发生风险。 方法 研究人群 来源于内蒙古医科大学附属医院 2013 年 1 月 1 日至 2014 年 1 月 1 日收治的糖尿病患者，采用系 统抽样方法选取 924 例 2 型糖尿病患者，其中 485 例青年（18~40 岁）2 型糖尿病患者，439 例老 年（>60 岁）2 型糖尿病患者。参考 CVD 风险评估测量模型，采用横断面研究方法对所选取患者 的高血压、肥胖 [ 体质量指数（BMI）>25 kg/m2]、高血糖、高胆固醇血症等 CVD 因素进行比较， 随访至 2019 年 1 月 1 日，观察两组患者发生 CVD 风险。 结果 青年与老年 2 型糖尿病患者糖 化血红蛋白（HbA1c）、BMI、收缩压、舒张压、总胆固醇、低密度脂蛋白水平均无统计学意 义（P > 0.05），且 CVD 风险因素高血压、肥胖、高血糖、高胆固醇血症比较差异无统计学意义 （P > 0.05）。青年和老年 2 型糖尿病患者无 CVD 风险因子、一个风险因素、两个风险因素、三个 风险因素、四个风险因素累加比例均无统计学意义（P > 0.05）。两组随访结束时 CVD 例数、随 访 5 年时 CVD 例数、两个 CVD 例数、两个以上 CVD 例数差异均无统计学意义（P > 0.05）。 结 论 青年 2 型糖尿病患者发生 CVD 风险并不低于老年患者。
Cardiovascular disease risk profiles in type 2 diabetic patients with different ages Yuan Congru, Dong Shuanghua, Huangfu Xiaoyan. Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China Corresponding author: Hangfu Xiaoyan, Email: dui502532@
【Abstract】 Objective To compare the risk of cardiovascular disease (CVD) in young and elderly type 2 diabetes. Methods The study population were derived from Affiliated Hospital of Inner Mongolia medical university from January 1, 2013 to January 1, 2014. A systematic sampling method was used to select 924 patients with type 2 diabetes, of which 485 were young patients (18-40 years old), 439 were elderly patients (>60 years old). Referring to the CVD risk assessment measurement model, cross-sectional study was used to compare the CVD factors such as hypertension, obesity[body mass index (BMI) >25 kg/m2], hyperglycemia and hypercholesterolemia in the patients. The follow-up continued to January 1, 2019, and the risk of CVD in both groups was observed. Results There was no statistically significant difference in glycosylated hemoglobin (HbA1c), BMI, systolic blood pressure, diastolic blood pressure, total cholesterol, and low-density lipoprotein between young and elderly patients with type 2 diabetes (P > 0.05). There was also no statistically significant difference in CVD risk factors including hypertension, obesity, hyperglycemia and hypercholesteremia (P > 0.05). Furthermore, there were no statistically significant differences of cumulative proportion in zero CVD risk factor, one risk factor, two risk factors, three risk factors, and four risk factors in young and elderly patients with type 2 diabetes (P > 0.05). There were no statistically significant differences in CVD cases at the end of follow-up time, CVD cases of follow up for five years, two CVD cases, and two or more CVD cases between the two groups (P > 0.05). Conclusion The risk of CVD in young patients with type 2 diabetes is not lower than that in elderly patients.
· 352 ·
心脑血管病防治 2020 年 8 月第 20 卷第 4 期 Cardio-Cerebrovasc Dis Prev Treat,August 2020,Vol.20,No.4
论著
不同年龄 2 型糖尿病患者心血管疾病的风 险性预测
苑丛茹 董双华 皇甫晓燕
【摘要】 目的 比较青年与老年 2 型糖尿病心血管疾病（CVD）发生风险。 方法 研究人群 来源于内蒙古医科大学附属医院 2013 年 1 月 1 日至 2014 年 1 月 1 日收治的糖尿病患者，采用系 统抽样方法选取 924 例 2 型糖尿病患者，其中 485 例青年（18~40 岁）2 型糖尿病患者，439 例老 年（>60 岁）2 型糖尿病患者。参考 CVD 风险评估测量模型，采用横断面研究方法对所选取患者 的高血压、肥胖 [ 体质量指数（BMI）>25 kg/m2]、高血糖、高胆固醇血症等 CVD 因素进行比较， 随访至 2019 年 1 月 1 日，观察两组患者发生 CVD 风险。 结果 青年与老年 2 型糖尿病患者糖 化血红蛋白（HbA1c）、BMI、收缩压、舒张压、总胆固醇、低密度脂蛋白水平均无统计学意 义（P > 0.05），且 CVD 风险因素高血压、肥胖、高血糖、高胆固醇血症比较差异无统计学意义 （P > 0.05）。青年和老年 2 型糖尿病患者无 CVD 风险因子、一个风险因素、两个风险因素、三个 风险因素、四个风险因素累加比例均无统计学意义（P > 0.05）。两组随访结束时 CVD 例数、随 访 5 年时 CVD 例数、两个 CVD 例数、两个以上 CVD 例数差异均无统计学意义（P > 0.05）。 结 论 青年 2 型糖尿病患者发生 CVD 风险并不低于老年患者。