吡虫啉、啶虫脒生产工艺论述

目录

摘要 (1)

英文摘要 (2)

第一章序言 (3)

1我国农药发展概况 (3)

2吡虫啉、啶虫脒性质介绍 (5)

2.1吡虫啉性质介绍 (5)

2.2啶虫脒性质介绍 (6)

第二章实习部分 (7)

1企业介绍 (7)

2生产原理 (9)

2.12-氯-5-氯甲基吡啶合成原理 (9)

2.2吡虫啉的合成原理 (11)

2.3啶虫脒的合成原理 (11)

3生产工艺流程简述 (11)

3.1二氯生产车间 (11)

3.1.1双环戊二烯裂解单元 (11)

3.1.25-降冰片烯-2-醛合成单元 (13)

3.1.32-氰乙基-5-降冰片烯-2-醛合成单元 (14)

3.1.42-亚甲基-4-氰基丁醛合成单元 (15)

3.1.52-氯-2-氯甲基-4-氰基丁醛合成单元 (17)

3.1.62-氯-5-氯甲基吡啶环合单元 (18)

3.2D M F法合成吡虫啉车间 (20)

3.2.1流程示意图 (20)

3.2.2各单元工艺规程 (20)

3.3啶虫脒的合成 (22)

3.3.1流程示意图 (22)

I

3.3.2各单元工艺规程 (22)

第三章实习心得及建议 (24)

1实习心得 (24)

2个人建议 (25)

参考文献 (26)

致谢 (28)

II

Content Abstract (1)

Abstract in English (2)

Chapter 1 Preamble (3)

1 The overview of pesticides in our country (3)

2 The introduction of the features of Idacloprid and Atamiprid (5)

2.1 The introduction of the features of Idacloprid (5)

2.2 The introduction of the features of Atamiprid (6)

Chapter 2 Part of Internship (7)

1 Introduction of company (7)

2 Principle of the production (9)

2.1 Principle of the the production of 2 - chloro -5 –chloromethylpyridine

(9)

2.2 Principle of the sythesis of imidacloprid (11)

2.3 Principle of the sythesis of acetamiprid (11)

3 Brief introduction on the processes (11)

3.1 Production workshop of 2 - chloro -5 –chloromethylpyridine (11)

3.1.1 Part of the cracking of dicyclopentadiene (11)

3.1.2 Part of the synthesis of 5-norbornene-2-aldehyde (13)

3.1.3 Part of the synthesis of 2 - cyanoethyl -5 - norbornene -2 –

aldehyde (14)

3.1.4 Part of the synthesis of 2-methyl-4-cyanide hyborxybutyric

aldehyde (15)

3.1.5 Part of the synthesis of 2-chloro-2 -chloromethyl -4 - Cyanide

hybroxybutyric aldehyde (17)

3.1.6 Part of the synthesis of 2 - chloro -5 –chloromethylpyridine (18)

3.2 Production workshop of DMF synthesis of imidacloprid (20)

III

3.2.1 The flow chart (20)

3.2.2 The operation rules of every parts (20)

3.3 Production workshop of acetamiprid (22)

3.3.1 The flow chart (22)

3.3.2 The operation rules of every parts (22)

Chapter 3 Internship experience and personal recommendations (24)

1 Internship experience (24)

2 Personal recommendations (25)

Reference (26)

Thanks (28)

IV

吡虫啉、啶虫脒生产工艺论述

摘要：农药工业在国民经济中占有重要地位，其发展与农业生产和人民生活的提高密切相关。随着人们环保意识及害虫抗药性的提高，农药品种需要不断更新。吡虫啉、啶虫脒作为新型烟碱类超高效杀虫剂，在农业生产中的应用越来越广泛。本文根据自己在山东海利尔药业集团原药生产基地实习学到的一些工艺及取得的一些经验，综述农药工业中2-氯-5-氯甲基吡啶、DMF 法合成吡虫啉以及啶虫脒的生产技术与实际生产中工艺参数要求，并对现有的生产工艺提出改革建议。

关键词：2-氯-5-氯甲基吡啶(二氯)；吡虫啉；啶虫脒；生产工艺

Research on the Production of Idacloprid and Atamiprid

Abstract：Pesticide industry plays an important role in the national economy. Its development is closely related with agricultural production and people's lives. With environmental protection and improvement of pest resistance, pesticide varieties need to be constantly updated. As a new type of nicotine pesticides of ultra-high efficiency , imidacloprid and acetamiprid are widely applied in

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