加州65标准---英文版
加州65(1)
加州65提案（Proposition 65），即《安全饮用水和有毒物质强制法令》(Safe Drinking Water and Toxic Enforcement Act)，1986年11月于美国加州颁布施行，旨在保护加州公民及加州饮用水资源免受已知具有致癌、致出生缺陷或其他生殖毒性的化学物质的污染，同时，告知加利福尼亚公民有关暴露在他们所购买的物品、家里的或工作场所中的化学物质或释放进环境的化学物质的危害。
|加州65清单加州65要求政府至少每年公布一次“加州已知的可导致癌症或生殖毒性的化学品清单”，简称加州65清单，目前已经有近千种化学物质被公布。
企业如有使用该清单中的物质，则必须给予“清晰且合理”的警告，否则相关企业必须用科学的数据来证明其物质浓度在消费者正常使用过程中，其摄入量小于安全港数值（safe harbor level）。
最新加州65清单下载：加州65清单下载-2018.05.25最新加州65安全港数值下载：加州65安全港数值-2017.05.17|加州65的核心要求1、禁止污染饮用水源：生产、使用、释放本列表上的化学物质或另外从事含本列表上的化学物质的活动的企业，不容许将提案列明的危险化学物质排放到饮用水里；2、提供清晰且合理的警告标签：某一种化学物质被列入管控清单后，制造商和经销商须在12个月内对列明的化学物质提供警告，除非暴露含量特别低，不会造成重大风险；|加州65涉及的产品加州65针对珠宝、服装、箱包、运动垫具、玩具和儿童保育用品、陶瓷玻璃制品、铝制炊具、自行车及其配件、电气装置和电线电缆等产品都做了规定，几乎覆盖了所有的产品，并对危险品的暴露场景进行列明。
|加州65和解协议加州65本身并未对有害物质设定限值，只有安全港数值（safe harbor level），而应用此安全港数值，需要企业提供大量的支撑数据。
当个人或团体质疑某产品中的某些有害化学品安全水平并提出诉讼，最终达成和解协议或者裁决结果。
about Ca 65
加州65号提案，即《1986年饮用水安全与毒性物质强制执行法》，于1986年11月颁发，其宗旨是保护美国加州居民及该州的饮用水水源，使水源不含已知可能导致癌症、出生缺陷或其他生殖发育危害的物质，并在出现该类物质时如实通知居民。
该法案被编纂列入加利福尼亚州健康和安全法典的第25249.5~25249.13章。
法案规定，从事买卖的个体，其雇员人数达10个或10个以上的（另有豁免的除外），须在含已获知可致癌或生殖毒性的化学物质的产品上加贴清晰、合理的警告标签，以避免与人体接触，且不得将这些化学物质排放到饮用水中。
警告信息可直接置于产品标签上，或采用在工作场所张贴标记、在租赁的建筑物内分发通知单、在报纸上登报通知等方式标示（如下图）。
法案要求加州政府出版具有致癌或生殖毒性的化学物质清单，清单每个季度进行更新。
从1987年首次出版以来，该清单中目前已包含约850种化学物质。
这些物质包括大量自然产生的和人工合成的化学物质，涉及用于杀虫剂、普通家用产品、食品、药物、染料或溶剂的添加剂或配料。
它们可用于制造业和建造业，也可以是化学过程的副产品，如机动车尾气。
所列化学物质包括烟草烟雾﹑金属（例如铅、镉和镍）和有机化学物质（例如邻苯二甲酸盐：BBP、DBP、DEHP、DINP、DIDP和DnOP等，以及多环芳香烃：苯并芘等）。
最新化学物质清单可通过“加州65提案列表”获取。
一旦某一种化学物质被列入清单后，制造商和经销商将须在一年内完成警告的执行，在20个月内终止化学物质排放至饮用水源头。
此日期过后，政府或个人执法者，包括代表公众利益的个人或组织，可对违反法规者提起诉讼。
加州65提案受控的产品范围包括：珠宝，玩具，电子设备，玻璃和陶瓷产品，纺织品，食品，药品，农用杀虫剂，染料，有机溶剂，建筑消耗品，汽车、香烟或天然气燃烧发出的化学物质，等等。
加州环境保护署（Cal/ EPA）辖下的环境健康危害评估办公室负责65提案的执行、更新和出版化学物质列表，以及开发物质等级数字指南（可致癌物质的NSRLs 和具生殖毒性化学物质的MADLs），企业可以通过以上文件，获知哪些物质需要警告标签，哪些化学物质被禁止释放到饮用水源中。
加州65 双酚s测试标准
加州65 双酚s测试标准
加州65双酚S（Bisphenol S, BPS）测试标准是针对双酚S这种化学物质在加州市场上的限制要求。
加州65号提案（California Proposition 65）是一个旨在保护加州居民免受潜在有害化学物质暴露影响的法规。
该提案要求制造商、分销商和零售商提供清晰的警告，以便消费者了解产品可能含有的潜在有害物质。
双酚S是一种与双酚A（BPA）类似的化学物质，常用于制造某些塑料和树脂。
由于双酚A被认为可能对健康产生负面影响，一些制造商开始转向使用双酚S作为替代品。
然而，加州65号提案对双酚S也有限制要求，以确保产品不会对人体健康造成危害。
针对双酚S的测试标准通常涉及以下几个方面：
限值要求：加州65号提案设定了双酚S在特定产品中的最大允许浓度限值。
制造商需要确保其产品中的双酚S含量不超过这些限值。
测试方法：为了确定产品中的双酚S含量，需要使用经过验证的测试方法。
这些方法可能包括色谱分析、质谱分析等化学分析技术。
警告标签：如果产品中的双酚S含量超过限值要求，制造商必须在产品上提供清晰的警告标签，告知消费者该产品可能含有潜在的有害物质。
cal 65 加州关于安全饮用水有毒物质法规
SAFE DRINKING WATER AND TOXIC ENFORCEMENT ACT OF 1986(Chapter 6.6 added by Proposition 65 1986 General Election)25249.5. Prohibition On Contaminating Drinking Water With Chemicals Known to Cause Cancer or Reproductive Toxicity. No person in the course of doing business shall knowingly discharge or release a chemical known to the state to cause cancer or reproductive toxicity into water or onto or into land where such chemical passes or probably will pass into any source of drinking water, notwithstanding any other provision or authorization of law except as provided in Section 25249.9.25249.6. Required Warning Before Exposure To Chemicals Known to Cause Cancer Or Reproductive Toxicity. No person in the course of doing business shall knowingly and intentionally expose any individual to a chemical known to the state to cause cancer or reproductive toxicity without first giving clear and reasonable warning to such individual, except as provided in Section 25249.10.25249.7. Enforcement.(a) Any person that violates or threatens to violate Section 25249.5 or 25249.6 may be enjoined in any court of competent jurisdiction.(b) (1) Any person who has violated Section 25249.5 or 25249.6 shall be liable for a civil penalty not to exceed two thousand five hundred dollars ($2500) per day for each violation in addition to any other penalty established by law. That civil penalty may be assessed and recovered in a civil action brought in any court of competent jurisdiction.(2) In assessing the amount of a civil penalty for a violation of this chapter, the court shall consider all of the following:(A) The nature and extent of the violation.(B) The number of, and severity of, the violations.(C) The economic effect of the penalty on the violator.(D) Whether the violator took good faith measures to comply with this chapter and the time these measures were taken.(E) The willfulness of the violator’s misconduct.(F) The deterrent effect that the imposition of the penalty would have on both the violator and the regulated community as a whole.(G) Any other factor that justice may require.(c) Actions pursuant to this section may be brought by the Attorney General in the name of the people of the State of California, by any district attorney, by any city attorney of a city having a population in excess of 750,000, or, with the consent of the district attorney, by a city prosecutor in any city or city and county having a full-time city prosecutor, or as provided in subdivision (d).(d) Actions pursuant to this section may be brought by any person in the public interest if both of the following requirements are met:(1) The private action is commenced more than 60 days from the date that the person has given notice of an alleged violation of Section 25249.5 or 25249.6 that is the subject of the private action to the Attorney General and the district attorney, city attorney, or prosecutor in whose jurisdiction the violation is alleged to have occurred, and to the alleged violator. If the notice alleges a violation of Section 25249.6, the notice of the alleged violation shall include acertificate of merit executed by the attorney for the noticing party, or by the noticing party, if the noticing party is not represented by an attorney. The certificate of merit shall state that the person executing the certificate has consulted with one or more persons with relevant and appropriate experience or expertise who has reviewed facts, studies, or other data regarding the exposure to the listed chemical that is the subject of the action, and that, based on that information, the person executing the certificate believes there is a reasonable and meritorious case for the private action. Factual information sufficient to establish the basis of the certificate of merit, including the information identified in paragraph (2) of subdivision (h), shall be attached to the certificate of merit that is served on the Attorney General.(2) Neither the Attorney General, any district attorney, any city attorney nor any prosecutor has commenced and is diligently prosecuting an action against the violation.(e) Any person bringing an action in the public interest pursuant to subdivision (d) and any person filing any action in which a violation of this chapter is alleged shall notify the Attorney General that the action has been filed. Neither this subdivision nor the procedures provided in subdivisions (f) to (j), inclusive, shall affect the requirements imposed by the statute or a court decision in existence on January 1, 2002 concerning whether any person filing any action in which a violation of this chapter is alleged is required to comply with the requirements of subdivision (d).(f) (1) Any person bringing an action in the public interest pursuant to subdivision (d), any person filing any action in which a violation of this chapter is alleged, or any private person settling any violation of this chapter alleged in a notice given pursuant to paragraph (1) of subdivision (d), shall, after the action or violation is either subject to a settlement or to a judgment, submit to the Attorney General a reporting form that includes the results of that settlement or judgment and the final disposition of the case, even if dismissed. At the time of the filing of any judgment pursuant to an action brought in the public interest pursuant to subdivision (d), or any action brought by a private person in which a violation of this chapter is alleged,the plaintiff shall file an affidavit verifying that the report required by this subdivision has been accurately completed and submitted to the Attorney General.(2) Any person bringing an action in the public interest pursuant to subdivision(d) or any private person bringing an action in which a violation of this chapter is alleged,shall, after the action is either subject to a settlement, with or without court approval, or to a judgment, submit to the Attorney General a report that includes information on any corrective action being taken as a part of the settlement or resolution of the action.(3) The Attorney General shall develop a reporting form that specifies the information that shall be reported, including, but not limited to, for purposes of subdivision (e), the date the action was filed, the nature of the relief sought, and for purposes of this subdivision, the amount of the settlement or civil penalty assessed, other financial terms of the settlement, and any other information the Attorney General deems appropriate.(4) If there is a settlement of an action brought by a person in the public interest under subdivision (d), the plaintiff shall submit the settlement, other than a voluntary dismissal in which no consideration is received from the defendant, to the court for approval upon noticed motion, and the court may approve the settlement only if the court makes all of the following findings:(A) Any warning that is required by the settlement complies with this chapter.(B) Any award of attorney’s fees is reasonable under California law.(C) Any penalty amount is reasonable based on the criteria set forth in paragraph (2) of subdivision (b).(5) The plaintiff subject to paragraph (4) has the burden of producing evidence sufficient to sustain each required finding. The plaintiff shall serve the motion and all supporting papers on the Attorney General, who may appear and participate in any proceeding without intervening in the case.(6) Neither this subdivision nor the procedures provided in subdivision (e) and subdivisions (g) to (j), inclusive, shall affect the requirements imposed by statute or a court decision in existence on the January 1, 2002 concerning whether claims raised by any person or public prosecutor not a party to the action are precluded by a settlement approved by the court.(g) The Attorney General shall maintain a record of the information submitted pursuant to subdivisions (e) and (f) and shall make this information available to the public.(h) (1) Except as provided in paragraph (2), the basis for the certificate of merit required by subdivision (d) is not discoverable. However, nothing in this subdivision shall preclude the discovery of information related to the certificate of merit if that information is relevant to the subject matter of the action and is otherwise discoverable, solely on the ground that it was used in support of the certificate of merit.(2) Upon the conclusion of an action brought pursuant to subdivision (d) with respect to any defendant, if the trial court determines that there was no actual or threatened exposure to a listed chemical, the court may, upon the motion of that alleged violator or upon the court’s own motion, review the basis for the belief of the person executing the certificate of merit, expressed in the certificate of merit, that an exposure to a listed chemical had occurred or was threatened. The information in the certificate of merit, including the identity of the persons consulted with and relied on by the certifier, and the facts, studies, or other data reviewed by those persons, shall be disclosed to the court in an in-camera proceeding at which the moving party shall not be present. If the court finds that there was no credible factual basis for the certifier’s belief that an exposure to a listed chemical has occurred or was threatened, then the action shall be deemed frivolous within the meaning of Section 128.6 or 128.7 of the Code of Civil Procedure, whichever provision is applicable to the action. The court shall not find a factual basis credible on the basis of a legal theory of liability that is frivolous within the meaning of Section 128.6 or 128.7 of the Code of Civil Procedure, whichever provision is applicable to the action.(i) The Attorney General may provide the factual information submitted to establish the basis of the certificate of merit on request to any district attorney, city attorney, or prosecutor within whose jurisdiction the violation is alleged to have occurred, or to any other state or federal government agency, but in all other respects the Attorney General shall maintain, and ensure that all recipients maintain, the submitted information as confidential official information to the full extent authorized in Section 1040 of the Evidence Code.(j) In any action brought by the Attorney General, a district attorney, a city attorney, or a prosecutor pursuant to this chapter, the Attorney General, district attorney, city attorney, or prosecutor may seek and recover costs and attorney’s fees on behalf of any party who provides a notice pursuant to subdivision (d) and who renders assistance in that action.25249.8. List Of Chemicals Known to Cause Cancer Or Reproductive Toxicity.(a) On or before March 1, 1987, the Governor shall cause to be published a list of those chemicals known to the state to cause cancer or reproductive toxicity within the meaning of thischapter, and he shall cause such list to be revised and republished in light of additional knowledge at least once per year thereafter. Such list shall include at a minimum those substances identified by reference in Labor Code Section 6382(b)(1) and those substances identified additionally by reference in Labor Code Section 6382(d).(b) A chemical is known to the state to cause cancer or reproductive toxicity within the meaning of this chapter if in the opinion of the state's qualified experts it has been clearly shown through scientifically valid testing according to generally accepted principles to cause cancer or reproductive toxicity, or if a body considered to be authoritative by such experts has formally identified it as causing cancer or reproductive toxicity, or if an agency of the state or federal government has formally required it to be labeled or identified as causing cancer or reproductive toxicity.(c) On or before January 1, 1989, and at least once per year thereafter, the Governor shall cause to be published a separate list of those chemicals that at the time of publication are required by state or federal law to have been tested for potential to cause cancer or reproductive toxicity but that the state's qualified experts have not found to have been adequately tested as required.(d) The Governor shall identify and consult with the state's qualified experts as necessary to carry out his duties under this section.(e) In carrying out the duties of the Governor under this section, the Governor and his designates shall not be considered to be adopting or amending a regulation within the meaning of the Administrative Procedure Act as defined in Government Code Section 11370.25249.9. Exemptions from Discharge Prohibition.(a) Section 25249.5 shall not apply to any discharge or release that takes places less than twenty months subsequent to the listing of the chemical in question on the list required to be published under subdivision (a) of Section 25249.8.(b) Section 25249.5 shall not apply to any discharge or release that meets both of the following criteria:(1) The discharge or release will not cause any significant amount of the discharged or released chemical to enter any source of drinking water.(2) The discharge or release is in conformity with all other laws and with every applicable regulation, permit, requirement, and order. In any action brought to enforce Section 25249.5, the burden of showing that a discharge or release meets the criteria of this subdivision shall be on the defendant.25249.10. Exemptions from Warning Requirement. Section 25249.6 shall not apply to any of the following:(a) An exposure for which federal law governs warning in a manner that preempts state authority.(b) An exposure that takes place less than twelve months subsequent to the listing of the chemical in question on the list required to be published under subdivision (a) ofSection 25249.8.(c) An exposure for which the person responsible can show that the exposure poses no significant risk assuming lifetime exposure at the level in question for substances known to the state to cause cancer, and that the exposure will have no observable effect assuming exposure at one thousand (1000) times the level in question for substances known to the state to causereproductive toxicity, based on evidence and standards of comparable scientific validity to the evidence and standards which form the scientific basis for the listing of such chemical pursuant to subdivision (a) of Section 25249.8. In any action brought to enforce Section 25249.6, the burden of showing that an exposure meets the criteria of this subdivision shall be on the defendant.25249.11. Definitions. For purposes of this chapter:(a) "Person" means an individual, trust, firm, joint stock company, corporation, company, partnership, limited liability company, and association.(b) "Person in the course of doing business" does not include any person employing fewer than 10 employees in his or her business; any city, county, or district or any department or agency thereof or the state or any department or agency thereof or the federal government or any department or agency thereof; or any entity in its operation of a public water system as defined in Section 4010.1.(c) "Significant amount" means any detectable amount except an amount which would meet the exemption test in subdivision (c) of Section 25249.10 if an individual were exposed to such an amount in drinking water.(d) "Source of drinking water" means either a present source of drinking water or water which is identified or designated in a water quality control plan adopted by a regional board as being suitable for domestic or municipal uses.(e) "Threaten to violate" means to create a condition in which there is a substantial probability that a violation will occur.(f) "Warning" within the meaning of Section 25249.6 need not be provided separately to each exposed individual and may be provided by general methods such as labels on consumer products, inclusion of notices in mailings to water customers, posting of notices, placing notices in public news media, and the like, provided that the warning accomplished is clear and reasonable. In order to minimize the burden on retail sellers of consumer products including foods, regulations implementing Section 25249.6 shall to the extent practicable place the obligation to provide any warning materials such as labels on the producer or packager rather than on the retail seller, except where the retail seller itself is responsible for introducing a chemical known to the state to cause cancer or reproductive toxicity into the consumer product in question.25249.12. (a) The Governor shall designate a lead agency and other agencies that may be required to implement this chapter, including this section. Each agency so designated may adopt and modify regulations, standards, and permits as necessary to conform with and implement this chapter and to further its purposes.(b) The Safe Drinking Water and Toxic Enforcement Fund is hereby established in the State Treasury. The director of the lead agency designated by the Governor to implement this chapter may expend the funds in the Safe Drinking Water and Toxic Enforcement Fund, upon appropriation by the Legislature, to implement and administer this chapter.(c) In addition to any other money that may be deposited in the Safe Drinking Water and Toxic Enforcement Fund, all of the following amounts shall be deposited in the fund:(1) Seventy-five percent of all civil and criminal penalties collected pursuant to this chapter.(2) Any interest earned upon the money deposited into the Safe Drinking Water and Toxic Enforcement Fund.(d) Twenty-five percent of all civil and criminal penalties collected pursuant to this chapter shall be paid to the office of the city attorney, city prosecutor, district attorney, or Attorney General, whichever office brought the action, or in the case of an action brought by a person under subdivision (d) of Section 25249.7, to that person.25249.13. Preservation Of Existing Rights, Obligations, and Penalties. Nothing in this chapter shall alter or diminish any legal obligation otherwise required in common law or by statute or regulation, and nothing in this chapter shall create or enlarge any defense in any action to enforce such legal obligation. Penalties and sanctions imposed under this chapter shall be in addition to any penalties or sanctions otherwise prescribed by law.25180.7. (a) Within the meaning of this section, a "designated government employee" is any person defined as a "designated employee" by Government Code Section 82019, as amended.(b) Any designated government employee who obtains information in the course of his official duties revealing the illegal discharge or threatened illegal discharge of a hazardous waste within the geographical area of his jurisdiction and who knows that such discharge or threatened discharge is likely to cause substantial injury to the public health or safety must, within seventy-two hours, disclose such information to the local Board of Supervisors and to the local health officer. No disclosure of information is required under this subdivision when otherwise prohibited by law, or when law enforcement personnel have determined that such disclosure would adversely affect an ongoing criminal investigation, or when the information is already general public knowledge within the locality affected by the discharge or threatened discharge.(c) Any designated government employee who knowingly and intentionally fails to disclose information required to be disclosed under subdivision (b) shall, upon conviction, be punished by imprisonment in the county jail for not more than one year or by imprisonment in state prison for not more than three years. The court may also impose upon the person a fine of not less than five thousand dollars ($5000) or more than twenty-five thousand dollars ($25,000). The felony conviction for violation of this section shall require forfeiture of government employment within thirty days of conviction.(d) Any local health officer who receives information pursuant to subdivision (b) shall take appropriate action to notify local news media and shall make such information available to the public without delay.25192. (a) All civil and criminal penalties collected pursuant to this chapter shall be apportioned in the following manner:(1) Fifty percent shall be deposited in the Hazardous Substance Account in the General Fund.(2) Twenty-five percent shall be paid to the office of the city attorney, city prosecutor, district attorney, or Attorney General, whichever office brought the action.(3) Twenty-five percent shall be paid to the department and used to fund the activity of the CUPA, the local health officer, or other local public officer or agency authorized to enforce the provisions of this chapter pursuant to Section 25180, whichever entity investigated the matter that led to the bringing of the action. If investigation by the local police department or sheriff's office or California Highway Patrol led to the bringing of the action, the CUPA, thelocal health officer, or the authorized officer or agency, shall pay a total of 40 percent of its portion under this subdivision to that investigating agency or agencies to be used for the same purpose. If more than one agency is eligible for payment under this paragraph, division of payment among the eligible agencies shall be in the discretion of the CUPA, the local health officer, or the authorized officer or agency.(b) If a reward is paid to a person pursuant to Section 25191.7, the amount of the reward shall be deducted from the amount of the civil penalty before the amount is apportioned pursuant to subdivision (a).。
美国加州pro65标准
美国加州pro65标准美国加州pro65标准是指加州《安全饮用水及有毒物质执行法案》（Proposition 65）的一项法规，旨在保护加州州民免受有毒物质的危害。
该标准要求企业在其产品中使用可能导致致癌、致畸形或其他生殖毒性的化学物质时，必须向公众提供警告。
这一法规于1986年通过，并于1988年正式实施，适用于加州境内销售的所有产品。
根据该标准，企业必须在其产品上标注警告，提醒消费者该产品中含有可能对健康造成危害的化学物质。
这些警告通常以“此产品含有一种或多种可能导致致癌、致畸形或其他生殖毒性的化学物质”的形式出现。
这些警告通常以文字、图像或标志的形式出现，并且必须明显易见，以便消费者能够清楚地了解到产品的潜在风险。
在制定警告标准时，加州环保署（OEHHA）会对化学物质的毒性进行评估，并确定其是否符合pro65标准的警告要求。
一旦化学物质被列入pro65清单，企业就必须遵守警告标准，并在其产品上提供相应的警告。
此外，企业还必须向加州环保署提交有关产品中化学物质含量的报告，以确保产品符合标准。
虽然pro65标准是加州的法规，但其影响却不仅限于加州。
许多企业为了避免在加州市场上遭受罚款或诉讼，都会在全国范围内遵守pro65标准，并在其产品上提供相应的警告。
因此，pro65标准实际上已成为了全美国范围内的一项重要法规。
然而，pro65标准也引发了一些争议。
一些批评者认为，该标准过于苛刻，导致了大量产品被贴上警告标签，从而对消费者造成了困扰。
同时，一些企业也表示，pro65标准的执行方式并不清晰，导致了对其产品的误判和不公平对待。
总的来说，美国加州pro65标准是一项旨在保护消费者免受有毒化学物质危害的重要法规。
虽然其执行方式可能存在一些争议，但其作为一项消费者保护法规的意义不可忽视。
在未来，我们可以期待pro65标准的进一步完善，以更好地平衡消费者权益和企业合规的需要。
加州65RoHSREACH卤素
REACH管控的产品范围及分类
化学品 几乎涵盖在欧盟市场上销售的所有产品，如
电子电气产品、轻工产品等 豁免（国防设备、食品、药品） 2008年6月1日REACH主管机构ECHA正式
运行
产品分类
自然状态下（存在的）或 通过生产过程获得的化学元 素及其化合物，包括加工过 程中为保持其稳定性而使用 的添加剂和加工过程中产生 的杂志，但不包括任何一种 在不影响其稳定性或改变其
成分的情况下就可被 分离的溶剂
甲醛，邻苯二甲酸盐， 甲苯，铬，镉………
指由两种或两种以上 物质组成的混合物
或溶液
油漆，胶水，洗发水， 清洁剂…….
由一种或多种物质和（或） 混合物组成的物体，在 生产过程中，它被赋予了
特定的形状、外观或设计， 比它的化学成分有更高 的最终功能
衣服，手机，水杯……
REACH法规管控要点
注册
◆物质≥1吨/年 ◆混合物中的物质≥1吨/年 ◆物品中有意释放的物质≥1吨/年
告知
◆SVHC候选物质及含有其的混合 物，应提供SDS（安全数据表）
◆物品中SVHC候选物质＞0.1%
评估
通报
◆由ECHA和各欧盟成员国官方执法 ◆物品中SVHC候选物质＞0.1%，
机构负责
◆物品中SVHC候选物质≥1吨/年
五、国推RoHS发展历程
《电子信息产品污染防治管理办法》 没有任何配套的标准？无法执行
2006年2月28发布
《电子信息产品污染控制重点管理目录制程序》 有点眉目………
2008年10月发布
《电子电气产品污染控制管理办法》 同时发布一系列配套标准
2010年7月征求意见 2011年8月正式实施
六.RoHS管控物质有哪些？
reach ca prop65标准
文章标题：探讨CA Prop65标准下的产品安全与健康保障一、引言在现代社会，人们对产品的安全和健康问题越来越重视。
而在美国加州，Prop65标准作为一项法规规定，对产品的有害物质的使用和披露提出了严格的要求。
在本文中，我们将深入探讨CA Prop65标准，分析其对产品安全与健康保障的重要性和意义。
二、了解CA Prop65标准1. CA Prop65标准是什么？CA Prop65标准是指加州65号法案（Proposition 65），它于1986年通过并在1988年实施。
该法案要求在加州销售和分发的产品中，必须对其中的化学物质做出披露，特别是那些已知对健康造成潜在危害的化学物质。
这就意味着生产商需要在产品上明确标示可能存在的有害物质，同时向消费者提供相关信息，以便消费者做出知情决策。
2. CA Prop65标准的制定背景CA Prop65标准的制定背景源自对环境和健康的保护。
人们对于食品、饮用水、药品、化妆品、清洁产品和其他日常用品中的有害物质日益关注，因此有必要对产品中的化学成分进行全面的披露和警示，以保障公众的权益和健康安全。
3. CA Prop65标准的适用范围CA Prop65标准适用于加州州内销售和分发的产品，包括但不限于食品、药品、饮料、化妆品、家居用品、玩具、电子产品等。
对于涉及到的有害物质，标准明确了一份名单，产品中含有名单上的化学物质的情况需要进行披露。
三、CA Prop65标准对产品安全与健康保障的重要性1. 提升产品的透明度和可信度CA Prop65标准的实施，使消费者更加清晰地了解到产品中所含有的可能危害健康的化学物质，从而增强了产品的透明度和可信度。
消费者可以据此做出理性的购买选择，对于患有过敏等特殊情况的用户来说尤为重要。
2. 促进企业生产安全环保的产品CA Prop65标准的出台，促使企业更加注重产品质量和安全性。
为了避免因产品含有有害物质而受到法律的处罚和消费者的投诉，企业将更加谨慎地选择原材料和生产工艺，生产更加环保和安全的产品，有利于提升企业的社会形象和品牌价值。
《加州65提案》(California Proposition 65-CA Prop 65)
STATE OF CALIFORNIAENVIRONMENTAL PROTECTION AGENCYOFFICE OF ENVIRONMENTAL HEALTH HAZARD ASSESSMENT SAFE DRINKING WATER AND TOXIC ENFORCEMENT ACT OF 1986CHEMICALS KNOWN TO THE STATE TO CAUSE CANCER OR REPRODUCTIVE TOXICITYFEBRUARY 5, 2010The Safe Drinking Water and Toxic Enforcement Act of 1986 requires that the Governor revise and republish at least once per year the list of chemicals known to the State to cause cancer or reproductive toxicity. The identification number indicated in the following list is the ChemicalAbstracts Service (CAS) Registry Number. No CAS number is given when several substances are presented as a single listing. The date refers to the initial appearance of the chemical on the list. For easy reference, chemicals which are shown underlined are newly added. Chemicals or endpoints shown in strikeout were placed on the Proposition 65 list on the date noted, and have subsequently been removed.Chemical Type of Toxicity CAS No. Date Listed A-alpha-C (2-Amino-9H-pyrido [2,3-b]indole) cancer 26148-68-5 January 1, 1990 Acetaldehyde cancer 75-07-0 April 1, 1988 Acetamide cancer 60-35-5 January 1, 1990 Acetazolamide developmental 59-66-5 August 20, 1999 Acetochlor cancer 34256-82-1 January 1, 1989 Acetohydroxamic acid developmental 546-88-3 April 1, 1990 2-Acetylaminofluorene cancer 53-96-3 July 1, 1987 Acifluorfen sodium cancer 62476-59-9 January 1, 1990 Acrylamide cancer 79-06-1 January 1, 1990 Acrylonitrile cancer 107-13-1 July 1, 1987 Actinomycin D cancer 50-76-0 October 1, 1989 developmental October 1, 1992 AF-2;[2-(2-furyl)-3-(5-nitro-2-furyl)] acrylamide cancer 3688-53-7 July 1, 1987 Aflatoxins cancer --- January 1, 1988 Alachlor cancer 15972-60-8 January 1, 1989 Alcoholic beverages, when associatedwith alcohol abuse cancer --- July 1, 1988 Aldrin cancer 309-00-2 July 1, 1988 All-trans retinoic acid developmental 302-79-4 January 1, 1989 Allyl chloride Delisted October 29, 1999 cancer 107-05-1 January 1, 1990 Alprazolam developmental 28981-97-7 July 1, 1990 Altretamine developmental, male 645-05-6 August 20, 1999 Amantadine hydrochloride developmental 665-66-7 February 27, 2001 Amikacin sulfate developmental 39831-55-5 July 1, 1990 2-Aminoanthraquinone cancer 117-79-3 October 1, 1989 p -Aminoazobenzene cancer 60-09-3 January 1, 1990 o -Aminoazotoluene cancer 97-56-3 July 1, 19874-Aminobiphenyl (4-amino- diphenyl)cancer 92-67-1 February 27, 1987 1-Amino-2,4-dibromo- anthraquinonecancer 81-49-2 August 26, 1997 3-Amino-9-ethylcarbazole hydrochloride cancer 6109-97-3 July 1, 1989 2-Aminofluorene cancer153-78-6 January 29, 1999 Aminoglutethimide developmental 125-84-8 July 1, 1990 Aminoglycosidesdevelopmental ---October 1, 1992 1-Amino-2-methylanthraquinone cancer 82-28-0 October 1, 1989 2-Amino-5-(5-nitro-2-furyl)-1,3,4- thiadiazolecancer712-68-5 July 1, 1987 4-Amino-2-nitrophenol cancer119-34-6 January 29, 1999 Aminopterindevelopmental, female 54-62-6 July 1, 1987 Amiodarone hydrochloride developmental, female, male19774-82-4 August 26, 1997 Amitraz developmental 33089-61-1 March 30, 1999 Amitrole cancer61-82-5 July 1, 1987 Amoxapine developmental 14028-44-5 May 15, 1998 Amsacrinecancer51264-14-3 August 7, 2009tert-Amyl methyl ether developmental 994-05-8 December 18, 2009 Anabolic steroidsfemale, male --- April 1, 1990Analgesic mixtures containing phenacetincancer --- February 27, 1987 Angiotensin converting enzyme (ACE) inhibitors developmental --- October 1, 1992 Anilinecancer 62-53-3 January 1, 1990 Aniline hydrochloride cancer 142-04-1 May 15, 1998 o -Anisidinecancer 90-04-0 July 1, 1987 o -Anisidine hydrochloride cancer134-29-2 July 1, 1987 Anisindionedevelopmental 117-37-3 October 1, 1992 Antimony oxide (Antimony trioxide) cancer 1309-64-4 October 1, 1990 Anthraquinone cancer 84-65-1 September 28, 2007 Aramite cancer 140-57-8 July 1, 1987Areca nutcancer --- February 3, 2006 Aristolochic acidscancer --- July 9, 2004Arsenic (inorganic arsenic compounds)cancer-- February 27, 1987 Arsenic (inorganic oxides) developmental ---May 1, 1997Asbestoscancer1332-21-4 February 27, 1987 Aspirin (NOTE: It is especially important not to use aspirin during the last three months of pregnancy, unless specifically directed to do so by a physician because it may cause problems in the unborn child orcomplications during delivery.) developmental, female50-78-2July 1, 1990Atenolol developmental 29122-68-7 August 26, 1997 Auramine cancer492-80-8 July 1, 1987Auranofin developmental 34031-32-8 January 29, 1999 Azacitidinecancer 320-67-2 January 1, 1992Azaserine cancer 115-02-6July 1, 1987Azathioprinecancerdevelopmental446-86-6 February 27, 1987 September 1, 1996 Azobenzene cancer 103-33-3 January 1, 1990Barbiturates developmental ---October 1, 1992 Beclomethasone dipropionate developmental 5534-09-8 May 15, 1998 Benomyl developmental, male 17804-35-2 July 1, 1991 Benthiavalicarb-isopropyl cancer 177406-68-7 July 1, 2008 Benz[a]anthracene cancer 56-55-3 July 1, 1987Benzene cancerdevelopmental, male71-43-2 February 27, 1987 December 26, 1997 Benzidine [and its salts] cancer 92-87-5 February 27, 1987 Benzidine-based dyes cancer --- October 1, 1992 Benzodiazepines developmental ---October 1, 1992 Benzo[b]fluoranthene cancer 205-99-2 July 1, 1987 Benzo[j]fluoranthene cancer 205-82-3 July 1, 1987 Benzo[k]fluoranthene cancer 207-08-9 July 1, 1987 Benzofuran cancer 271-89-6 October 1, 1990 Benzo[a]pyrene cancer 50-32-8 July 1, 1987 Benzotrichloride cancer 98-07-7 July 1, 1987 Benzphetamine hydrochloride developmental 5411-22-3 April 1, 1990 Benzyl chloride cancer 100-44-7 January 1, 1990 Benzyl violet 4B cancer 1694-09-3 July 1, 1987 Beryllium and beryllium compounds cancer --- October 1, 1987 Betel quid with tobacco cancer --- January 1, 1990 Betel quid without tobacco cancer ---February 3, 2006 2,2-Bis(bromomethyl)-1,3- propanediolcancer 3296-90-0 May 1, 1996 Bis(2-chloroethyl)ether cancer 111-44-4 April 1, 1988N,N-Bis(2-chloroethyl)-2-naphthylamine (Chlornapazine)cancer494-03-1 February 27, 1987 Bischloroethyl nitrosourea (BCNU) (Carmustine) cancer developmental 154-93-8 July 1, 1987 July 1, 1990Bis(chloromethyl)ether cancer542-88-1 February 27, 1987 Bis(2-chloro-1-methylethyl)ether,technical gradecancer --- October 29, 1999 Bitumens, extracts of steam-refined and air refined cancer ---January 1, 1990 Bracken fern cancer ---January 1, 1990 Bromacil lithium salt developmentalmale53404-19-6 May 18, 1999 January 17, 2003 Bromate cancer 15541-45-4 May 31, 2002 Bromodichloromethane cancer 75-27-4 January 1, 1990 Bromoethane cancer 74-96-4 December 22, 2000 Bromoform cancer 75-25-2 April 1, 19911-Bromopropane (1-BP) developmental, female,male106-94-5 December 7, 2004 2-Bromopropane (2-BP) female, male 75-26-3 May 31, 2005 Bromoxynil developmental 1689-84-5 October 1, 1990 Bromoxynil octanoate developmental1689-99-2May 18, 1999Butabarbital sodium developmental 143-81-7 October 1, 1992 1,3-Butadiene cancer106-99-0 April 1, 1988 1,3-Butadienedevelopmental, female, male 106-99-0 April 16, 2004 1,4-Butanediol dimethanesulfonate (Busulfan)cancerdevelopmental 55-98-1 February 27, 1987 January 1, 1989 Butylated hydroxyanisole cancer25013-16-5 January 1, 1990 Butyl benzyl phthalate (BBP) developmental 85-68-7 December 2, 2005 n-Butyl glycidyl ether male 2426-08-6 August 7, 2009 beta-Butyrolactone cancer 3068-88-0 July 1, 1987Cacodylic acid cancer75-60-5 May 1, 1996 Cadmiumdevelopmental, male --- May 1, 1997 Cadmium and cadmium compounds cancer--- October 1, 1987 Caffeic acid cancer 331-39-5 October 1, 1994 Captafol cancer 2425-06-1 October 1, 1988 Captancancer133-06-2 January 1, 1990 Carbamazepine developmental 298-46-4 January 29, 1999 Carbaryl cancer63-25-2 February 5, 2010 Carbaryl developmental, male 63-25-2 August 7, 2009 Carbazolecancer 86-74-8 May 1, 1996Carbon black (airborne, unbound particles of respirable size) cancer1333-86-4 February 21, 2003 Carbon disulfidedevelopmental, female, male75-15-0 July 1, 1989 Carbon monoxide developmental 630-08-0 July 1, 1989 Carbon tetrachloride cancer 56-23-5 October 1, 1987 Carbon-black extracts cancer---January 1, 1990 Carboplatindevelopmental 41575-94-4 July 1, 1990N-Carboxymethyl-N-nitrosourea cancer 60391-92-6 January 25, 2002 Catecholcancer 120-80-9 July 15, 2003 Ceramic fibers (airborne particles of respirable size)cancer --- July 1, 1990 Certain combined chemotherapy for lymphomas cancer --- February 27, 1987 Chenodiol developmental 474-25-9 April 1, 1990Chlorambucilcancerdevelopmental 305-03-3 February 27, 1987 January 1, 1989 Chloramphenicolcancer56-75-7 October 1, 1989 Chlorcyclizine hydrochloride developmental 1620-21-9 July 1, 1987 Chlordanecancer 57-74-9 July 1, 1988 Chlordecone (Kepone) cancerdevelopmental 143-50-0 January 1, 1988 January 1, 1989 Chlordiazepoxidedevelopmental 58-25-3 January 1, 1992 Chlordiazepoxide hydrochloride developmental 438-41-5 January 1, 1992 Chlordimeform cancer 6164-98-3 January 1, 1989 Chlorendic acidcancer 115-28-6 July 1, 1989 Chlorinated paraffins (Average Chain length, C12; ap- proximately 60 percent chlorine by weight)cancer108171-26-2July 1, 1989p -Chloroanilinecancer 106-47-8 October 1, 1994 p -Chloroaniline hydrochloride cancer 20265-96-7 May 15, 1998 Chlorodibromomethane Delisted October 29, 1999 cancer 124-48-1 January 1, 1990 Chloroethane (Ethyl chloride) cancer 75-00-3 July 1, 1990 1-(2-Chloroethyl)-3-cyclohexyl- 1-nitrosourea (CCNU) (Lomustine)cancerdevelopmental 13010-47-4 January 1, 1988 July 1, 1990 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea (Methyl-CCNU) cancer 13909-09-6 October 1, 1988 Chloroform cancer67-66-3 October 1, 1987 Chloroformdevelopmental 67-66-3 August 7, 2009 Chloromethyl methyl ether (technical grade)cancer 107-30-2 February 27, 1987 3-Chloro-2-methylpropene cancer 563-47-3 July 1, 19891-Chloro-4-nitrobenzenecancer 100-00-5 October 29, 1999 4-Chloro-o -phenylenediamine cancer 95-83-0 January 1, 1988 Chloroprenecancer 126-99-8 June 2, 2000 2-Chloropropionic acid male 598-78-7 August 7, 2009 Chlorothalonilcancer 1897-45-6 January 1, 1989 p -Chloro-o -toluidinecancer 95-69-2 January 1, 1990 p-Chloro-o -toluidine, strong acid salts ofcancer --- May 15, 1998 5-Chloro-o -toluidine and its strong acid salts cancer---October 24, 1997 Chlorotrianisene cancer 569-57-3 September 1, 1996 Chlorozotocin cancer54749-90-5 January 1, 1992 Chlorsulfurondevelopmental, female, male64902-72-3 May 14, 1999 Chromium (hexavalent compounds) cancer--- February 27, 1987 Chromium (hexavalent compounds) developmental female,male--- December 19, 2008 Chrysene cancer 218-01-9 January 1, 1990 C.I. Acid Red 114 cancer 6459-94-5 July 1, 1992 C.I. Basic Red 9 monohydrochloride cancer 569-61-9 July 1, 1989 C.I. Direct Blue 15 cancer 2429-74-5 August 26, 1997 C.I. Direct Blue 218 cancer 28407-37-6 August 26, 1997 C.I. Solvent Yellow 14 cancer 842-07-9 May 15, 1998 Ciclosporin (Cyclosporin A; Cyclosporine) cancer 59865-13-3 79217-60-0 January 1, 1992 Cidofovir cancer, developmental,female, male113852-37-2 January 29, 1999 Cinnamyl anthranilate cancer 87-29-6 July 1, 1989 Cisplatin cancer 15663-27-1 October 1, 1988 Citrus Red No. 2 cancer 6358-53-8 October 1, 1989 Cladribine developmental 4291-63-8 September 1, 1996 Clarithromycin developmental 81103-11-9 May 1, 1997 Clobetasol propionate developmental, female 25122-46-7 May 15, 1998Clofibrate cancer 637-07-0 September 1, 1996 Clomiphene citrate developmental 50-41-9 April 1, 1990 Clorazepate dipotassium developmental57109-90-7October 1, 1992Cobalt metal powder cancer 7440-48-4 July 1, 1992 Cobalt [II] oxide cancer 1307-96-6 July 1, 1992 Cobalt sulfatecancer 10124-43-3 May 20, 2005 Cobalt sulfate heptahydrate cancer10026-24-1 June 2, 2000 Cocainedevelopmental, female 50-36-2 July 1, 1989 Codeine phosphate developmental 52-28-8 May 15, 1998Coke oven emissions cancer---February 27, 1987 Colchicinedevelopmental, male 64-86-8 October 1, 1992 Conjugated estrogenscancerdevelopmental ---February 27, 1987 April 1, 1990 Creosotes cancer ---October 1, 1988 p -Cresidine cancer 120-71-8 January 1, 1988 Cupferron cancer135-20-6 January 1, 1988 Cyanazine developmental 21725-46-2 April 1, 1990 Cycasin cancer14901-08-7 January 1, 1988 Cycloatedevelopmental 1134-23-2 March 19, 1999 Cyclohexanol Delisted January 25, 2002 male108-93-0 November 6, 1998 Cycloheximidedevelopmental 66-81-9 January 1, 1989 Cyclophosphamide (anhydrous) cancerdevelopmental, female, male 50-18-0 February 27, 1987 January 1, 1989 Cyclophosphamide (hydrated) cancerdevelopmental, female, male6055-19-2 February 27, 1987 January 1, 1989 Cyhexatin developmental 13121-70-5 January 1, 1989 Cytarabine developmental 147-94-4 January 1, 1989 Cytembena cancer 21739-91-3 May 15, 1998D&C Orange No. 17 cancer 3468-63-1 July 1, 1990 D&C Red No. 8 cancer 2092-56-0 October 1, 1990 D&C Red No. 9 cancer 5160-02-1 July 1, 1990 D&C Red No. 19 cancer 81-88-9 July 1, 1990 Dacarbazinecancerdevelopmental 4342-03-4 January 1, 1988 January 29, 1999 Daminozide cancer1596-84-5 January 1, 1990 Danazoldevelopmental 17230-88-5 April 1, 1990 Dantron (Chrysazin; 1,8- Dihydroxy-anthraquinone) cancer117-10-2 January 1, 1992 Daunomycincancer20830-81-3 January 1, 1988 Daunorubicin hydrochloride developmental23541-50-6 July 1, 1990 2,4-D butyric aciddevelopmental, male 94-82-6 June 18, 1999 DDD (Dichlorodiphenyl- dichloroethane) cancer 72-54-8 January 1, 1989 DDE (Dichlorodi-phenyldichloroethylene) cancer 72-55-9 January 1, 1989 DDT (Dichlorodi-phenyltrichloroethane) cancer50-29-3 October 1 , 1987 o,p’-DDT developmental, female, male789-02-6 May 15, 1998 p,p’-DDTdevelopmental, female, male50-29-3May 15, 1998DDVP (Dichlorvos) cancer62-73-7 January 1, 1989 2,4-DP (dichloroprop)Delisted January 25, 2002 developmental 120-36-5 April 27, 1999 N,N’-Diacetylbenzidine cancer 613-35-4 October 1, 1989 2,4-Diaminoanisolecancer 615-05-4 October 1, 1990 2,4-Diaminoanisole sulfate cancer 39156-41-7 January 1, 1988 4,4’-Diaminodiphenyl ether (4,4’-Oxydianiline) cancer 101-80-4 January 1, 1988 2,4-Diaminotoluenecancer95-80-7 January 1, 1988 Demeclocycline hydrochloride (internal use)developmental 64-73-3 January 1, 1992 Diaminotoluene (mixed) cancer---January 1, 1990 Diazepamdevelopmental 439-14-5 January 1, 1992 Diazoaminobenzene cancer136-35-6 May 20, 2005Diazoxidedevelopmental 364-98-7 February 27, 2001 Dibenz[a,h]acridine cancer 226-36-8 January 1, 1988 Dibenz[a,j]acridine cancer 224-42-0 January 1, 1988 Dibenz[a,h]anthracene cancer 53-70-3 January 1, 1988 7H-Dibenzo[c,g]carbazole cancer 194-59-2 January 1, 1988 Dibenzo[a,e]pyrene cancer 192-65-4 January 1, 1988 Dibenzo[a,h]pyrene cancer 189-64-0 January 1, 1988 Dibenzo[a,i]pyrene cancer 189-55-9 January 1, 1988 Dibenzo[a,l]pyrene cancer 191-30-0 January 1, 1988 Dibromoacetic acidcancer 631-64-1 June 17, 2008 1,2-Dibromo-3-chloropropane (DBCP)cancer male 96-12-8 July 1, 1987February 27, 1987 2,3-Dibromo-1-propanol cancer 96-13-9 October 1, 1994 Dichloroacetic acid cancer 79-43-6 May 1, 1996 Dichloroacetic acid male 79-43-6 August 7, 2009 p -Dichlorobenzene cancer 106-46-7 January 1, 1989 3,3’-Dichlorobenzidine cancer 91-94-1 October 1, 1987 3,3’-Dichlorobenzidine dihydrochloridecancer 612-83-9 May 15, 1998 1,4-Dichloro-2-butenecancer 764-41-0 January 1, 1990 3,3’-Dichloro-4,4’-diaminodiphenyl ethercancer 28434-86-8 January 1, 1988 1,1-Dichloroethanecancer 75-34-3 January 1, 1990 Dichloromethane (Methylene chloride) cancer75-09-2 April 1, 1988 Dichlorophene developmental 97-23-4 April 27, 1999 Dichlorphenamide developmental 120-97-8 February 27, 2001 Diclofop methyldevelopmental 51338-27-3 March 5, 1999 1,2-Dichloropropane cancer 78-87-5 January 1, 1990 1,3-Dichloropropene cancer542-75-6 January 1, 1989 Dicumarol developmental 66-76-2 October 1, 1992 Dieldrin cancer 60-57-1 July 1, 1988 Dienestrolcancer 84-17-3 January 1, 1990 Diepoxybutanecancer 1464-53-5 January 1, 1988 Diesel engine exhaustcancer ---October 1, 1990 Di(2-ethylhexyl)phthalate (DEHP) cancerdevelopmental, male 117-81-7 January 1, 1988 October 24, 2003 1,2-Diethylhydrazinecancer1615-80-1January 1, 1988Diethylstilbestrol (DES)cancerdevelopmental 56-53-1 February 27, 1987 July 1, 1987 Diethyl sulfate cancer64-67-5 January 1, 1988 Diflunisaldevelopmental, female 22494-42-4 January 29, 1999 Diglycidyl ethermale 2238-07-5 August 7, 2009 Diglycidyl resorcinol ether (DGRE) cancer101-90-6 July 1, 1989 Dihydroergotamine mesylate developmental 6190-39-2 May 1, 1997 Dihydrosafrolecancer94-58-6 January 1, 1988 Di-n -butyl phthalate (DBP) developmental, female, male84-74-2 December 2, 2005 Di-n -hexyl phthalate (DnHP) female, male 84-75-3 December 2, 2005 Di-isodecyl phthalate (DIDP) developmental 68515-49-1/ 26761-40-0 April 20, 2007 Diisopropyl sulfatecancer2973-10-6 April 1, 1993Diltiazem hydrochloride developmental 33286-22-5 February 27, 2001 3,3’-Dimethoxybenzidine (o -Dianisidine)cancer 119-90-4 January 1, 1988 3,3’-Dimethoxybenzidine dihydrochloride(o -Dianisidine dihydrochloride) cancer 20325-40-0 October 1, 1990 3,3’-Dimethoxybenzidine-based dyes metabolized to 3,3’-dimethoxybenzidinecancer --- June 11, 2004 3,3’-Dimethylbenzidine-based dyes metabolized to 3,3’- dimethylbenzidinecancer ---June 11, 2004 4-Dimethylaminoazobenzene cancer 60-11-7 January 1, 1988 trans -2-[(Dimethylamino)methyl- imino]-5-[2-(5-nitro-2-furyl)vinyl]- 1,3,4-oxadiazolecancer 55738-54-0 January 1, 1988 7,12-Dimethylbenz(a)anthracene cancer 57-97-6 January 1, 1990 3,3’-Dimethylbenzidine (ortho-Tolidine)cancer 119-93-7 January 1, 1988 3,3’-Dimethylbenzidine dihydrochloridecancer 612-82-8 April 1, 1992 Dimethylcarbamoyl chloride cancer 79-44-7 January 1, 1988 1,1-Dimethylhydrazine (UDMH) cancer 57-14-7 October 1, 1989 1,2-Dimethylhydrazine cancer 540-73-8 January 1, 1988 Dimethyl sulfatecancer 77-78-1 January 1, 1988 Dimethylvinylchloride cancer 513-37-1 July 1, 1989 m -Dinitrobenzene male 99-65-0 July 1, 1990 o -Dinitrobenzene male 528-29-0 July 1, 1990 p -Dinitrobenzenemale 100-25-4 July 1, 1990 3,7-Dinitrofluoranthene cancer 105735-71-5 August 26, 1997 3,9-Dinitrofluoranthene cancer 22506-53-2 August 26, 1997 1,6-Dinitropyrene cancer 42397-64-8 October 1, 1990 1,8-Dinitropyrenecancer42397-65-9 October 1, 1990 Dinitrotoluene (technical grade) female, male --- August 20, 1999 Dinitrotoluene mixture, 2,4-/2,6- cancer ---May 1, 1996 2,4-Dinitrotoluenecancer male121-14-2July 1, 1988 August 20, 19992,6-Dinitrotoluenecancer male606-20-2 July 1, 1995 August 20, 1999 Dinocap developmental39300-45-3 April 1, 1990 Dinoseb developmental, male 88-85-7 January 1, 1989 1,4-Dioxanecancer 123-91-1 January 1, 1988 Diphenylhydantoin (Phenytoin) cancerdevelopmental 57-41-0 January 1, 1988 July 1, 1987 Diphenylhydantoin (Phenytoin), sodium saltcancer 630-93-3 January 1, 1988 Di-n -propyl isocinchomeronate (MGK Repellent 326)cancer 136-45-8 May 1, 1996 Direct Black 38 (technical grade) cancer 1937-37-7 January 1, 1988 Direct Blue 6 (technical grade) cancer 2602-46-2 January 1, 1988 Direct Brown 95 (technical grade) cancer16071-86-6 October 1, 1988 Disodium cyanodithio- imidocarbonate developmental 138-93-2 March 30, 1999 Disperse Blue 1 cancer 2475-45-8 October 1, 1990 Diuroncancer 330-54-1 May 31, 2002 Doxorubicin hydrochloride (Adriamycin)cancer25316-40-9 July 1, 1987 Doxorubicin hydrochloride (Adriamycin)developmental, male 25316-40-9 January 29, 1999 Doxycycline (internal use)developmental 564-25-0 July 1, 1990 Doxycycline calcium (internal use) developmental 94088-85-4 January 1, 1992 Doxycycline hyclate (internal use) developmental 24390-14-5 October 1, 1991 Doxycycline monohydrate (internal use) developmental 17086-28-1 October 1, 1991Endrindevelopmental 72-20-8 May 15, 1998 Environmental tobacco smoke (ETS)developmental --- June 9, 2006 Epichlorohydrin cancer male106-89-8 October 1, 1987 September 1, 1996 Ergotamine tartrate developmental 379-79-3 April 1, 1990 Erionitecancer12510-42-8/ 66733-21-9 October 1, 1988 Estradiol 17B cancer 50-28-2 January 1, 1988 Estragolecancer 140-67-0 October 29, 1999 Estrogens, steroidal cancer ---August 19, 2005 Estrone cancer53-16-7 January 1, 1988 Estropipate cancer, developmental 7280-37-7 August 26, 1997 Ethinylestradiol cancer57-63-6 January 1, 1988 Ethionamide developmental 536-33-4 August 26, 1997 Ethoprop cancer 13194-48-4 February 27, 2001 Ethyl acrylatecancer140-88-5 July 1, 1989 Ethyl alcohol in alcoholic beverages developmental ---October 1, 1987 Ethylbenzenecancer 100-41-4 June 11, 2004Ethyl-tert-butyl ethermale637-92-3 December 18, 2009 Ethyl dipropylthiocarbamate developmental 759-94-4 April 27, 1999 Ethyl-4,4’-dichlorobenzilatecancer510-15-6January 1, 1990Ethylene dibromidecancerdevelopmental, male 106-93-4 July 1, 1987 May 15, 1998 Ethylene dichloride (1,2-Dichloroethane)cancer107-06-2 October 1, 1987 Ethylene glycol monoethyl ether developmental, male 110-80-5 January 1, 1989 Ethylene glycol monoethyl ether acetatedevelopmental, male 111-15-9 January 1, 1993 Ethylene glycol monomethyl ether developmental, male 109-86-4 January 1, 1989 Ethylene glycol monomethyl ether acetate developmental, male 110-49-6 January 1, 1993 Ethyleneimine cancer 151-56-4 January 1, 1988 Ethylene oxide cancer female75-21-8 July 1, 1987February 27, 1987developmental, maleAugust 7, 2009 Ethylene thiourea cancerdevelopmental 96-45-7 January 1, 1988 January 1, 1993 2-Ethylhexanoic acid developmental 149-57-5 August 7, 2009 Ethyl methanesulfonate cancer62-50-0 January 1, 1988 Etodolac developmental, female 41340-25-4 August 20, 1999 Etoposide developmental 33419-42-0 July 1, 1990 Etretinate developmental 54350-48-0 July 1, 1987Fenoxaprop ethyl developmental 66441-23-4 March 26, 1999 Fenoxycarb cancer72490-01-8 June 2, 2000Filgrastimdevelopmental 121181-53-1 February 27, 2001 Fluazifop butyl developmental69806-50-4 November 6, 1998 Flunisolide developmental, female 3385-03-3 May 15, 1998 Fluorouracildevelopmental 51-21-8 January 1, 1989 Fluoxymesteronedevelopmental 76-43-7 April 1, 1990 Flurazepam hydrochloride developmental1172-18-5 October 1, 1992 Flurbiprofen developmental, female 5104-49-4 August 20, 1999 Flutamidedevelopmental 13311-84-7 July 1, 1990 Fluticasone propionate developmental 80474-14-2 May 15, 1998Fluvalinate developmental 69409-94-5 November 6, 1998 Folpetcancer 133-07-3 January 1, 1989 Formaldehyde (gas)cancer 50-00-0 January 1, 1988 2-(2-Formylhydrazino)-4- (5-nitro-2-furyl)thiazole cancer3570-75-0 January 1, 1988 Fumonisin B 1 cancer 116355-83-0 November 14, 2003 Furancancer 110-00-9 October 1, 1993 Furazolidone cancer 67-45-8 January 1, 1990 Furmecyclox cancer 60568-05-0 January 1, 1990 Fusarin C cancer 79748-81-5 July 1, 1995Gallium arsenide cancer1303-00-0 August 1, 2008 Ganciclovircancer, developmental, male82410-32-0 August 26, 1997 Ganciclovir sodiumdevelopmental, male 107910-75-8 August 26, 1997 Gasoline engine exhaust (condensates/extracts)cancer---October 1, 1990Gemfibrozilcancerfemale, male 25812-30-0 December 22, 2000 August 20, 1999 Glasswool fibers (airborne particles of respirable size)cancer ---July 1, 1990 Glu-P-1 (2-Amino-6-methyldipyrido [1,2- a:3’,2’-d]imidazole) cancer 67730-11-4 January 1, 1990 Glu-P-2 (2-Aminodipyrido [1,2-a:3’,2’-d]imidazole) cancer67730-10-3 January 1, 1990 Glycidaldehyde cancer 765-34-4 January 1, 1988 Glycidolcancer556-52-5 July 1, 1990 Goserelin acetate developmental, female, male 65807-02-5 August 26, 1997 Griseofulvincancer 126-07-8 January 1, 1990 Gyromitrin (Acetaldehyde methylformylhydrazone) cancer16568-02-8 January 1, 1988Halazepamdevelopmental 23092-17-3 July 1, 1990 Halobetasol propionate developmental66852-54-8 August 20, 1999 Haloperidol developmental, female 52-86-8 January 29, 1999 Halothane developmental 151-67-7 September 1, 1996 HC Blue 1 cancer 2784-94-3 July 1, 1989 Heptachlorcancerdevelopmental 76-44-8 July 1, 1988 August 20, 1999 Heptachlor epoxidecancer 1024-57-3 July 1, 1988 Herbal remedies containing plant species of the genus Aristolochia cancer --- July 9, 2004 Hexachlorobenzenecancerdevelopmental 118-74-1 October 1, 1987 January 1, 1989 Hexachlorocyclohexane (technical grade)cancer ---October 1, 1987 Hexachlorodibenzodioxin cancer 34465-46-8 April 1, 1988 Hexachloroethanecancer 67-72-1 July 1, 1990 2,4-Hexadienal (89% trans, trans isomer; 11% cis, trans isomer) cancer--- March 4, 2005 Hexafluoroacetonemale 684-16-2 August 1, 2008 Hexamethylphosphoramide cancer male680-31-9 January 1, 1988 October 1, 1994 Histrelin acetate developmental---May 15, 1998 Hydramethylnon developmental, male 67485-29-4 March 5, 1999 Hydrazinecancer 302-01-2 January 1, 1988 Hydrazine sulfate cancer 10034-93-2 January 1, 1988 Hydrazobenzene (1,2-Diphenylhydrazine)cancer122-66-7 January 1, 1988 1-Hydroxyanthraquinone cancer129-43-1 May 27, 2005 Hydroxyurea developmental 127-07-1 May 1, 1997Idarubicin hydrochloride developmental, male 57852-57-0 August 20, 1999 Ifosfamide developmental 3778-73-2 July 1, 1990 Iodine-131developmental 10043-66-0 January 1, 1989 Indeno[1,2,3-cd]pyrenecancer193-39-5January 1, 1988Indium phosphidecancer 22398-80-7 February 27, 2001 IQ (2-Amino-3-methylimidazo [4,5-f] quinoline) cancer 76180-96-6 April 1, 1990 Iprodione cancer 36734-19-7 May 1, 1996 Iprovalicarbcancer 140923-17-7 140923-25-7 June 1, 2007 Iron dextran complex cancer 9004-66-4 January 1, 1988 Isobutyl nitrite cancer 542-56-3 May 1, 1996 Isoprenecancer 78-79-5 May 1, 1996 Isosafrole Delisted December 8, 2006 cancer120-58-1 October 1, 1989 Isotretinoin developmental 4759-48-2 July 1, 1987Isoxaflutole cancer 141112-29-0 December 22, 2000Lactofen cancer 77501-63-4 January 1, 1989 Lasiocarpine cancer303-34-4 April 1, 1988Leaddevelopmental, female, male ---February 27, 1987 Lead and lead compounds cancer ---October 1, 1992 Lead acetate cancer 301-04-2 January 1, 1988 Lead phosphate cancer 7446-27-7 April 1, 1988 Lead subacetate cancer1335-32-6 October 1, 1989 Leuprolide acetatedevelopmental, female, male74381-53-6 August 26, 1997 Levodopadevelopmental 59-92-7 January 29, 1999 Levonorgestrel implantsfemale 797-63-7 May 15, 1998 Lindane and other hexachloro- cyclohexane isomers cancer ---October 1, 1989 Linurondevelopmental 330-55-2 March 19, 1999 Lithium carbonate developmental 554-13-2 January 1, 1991 Lithium citrate developmental 919-16-4 January 1, 1991 Lorazepam developmental 846-49-1 July 1, 1990 Lovastatin developmental 75330-75-5 October 1, 1992 Lynestrenol cancer 52-76-6 February 27, 2001Mancozeb cancer 8018-01-7 January 1, 1990 Manebcancer 12427-38-2 January 1, 1990 Marijuana smokecancer ---June 19, 2009 Me-A-alpha-C (2-Amino-3-methyl- 9H-pyrido[2,3-b]indole) cancer 68006-83-7 January 1, 1990 Mebendazoledevelopmental 31431-39-7 August 20, 1999 Medroxyprogesterone acetate cancerdevelopmental 71-58-9 January 1, 1990 April 1, 1990 Megestrol acetatedevelopmental 595-33-5 January 1, 1991 MeIQ (2-Amino-3,4-dimethyl- imidazo[4,5-f]quinoline)cancer 77094-11-2 October 1, 1994 MeIQx (2-Amino-3,8-dimethyl- imidazo[4,5-f]quinoxaline) cancer 77500-04-0 October 1, 1994 Melphalan cancerdevelopmental 148-82-3 February 27, 1987 July 1, 1990 Menotropinsdevelopmental9002-68-0April 1, 1990。
美国加州65标准
美国加州65标准（CP65）proposition 65加州第65号提案从颁布到现在已有20余年，一直秉持减少有毒化学物质的暴露的宗旨。
它允许加州居民通过一定的方式消除消费品和工业中的致癌物质和生殖毒性化学物质的行为。
自第65号提案制定以来，众多关于消费品中含有毒化学物质诉讼案在加州不断出现，从而引领整个美国一系列的限制标准的实施。
第65号提案，即《加州安全饮用水和有毒物执行法》，于1986 年11 月经加州居民投票，以压倒性的票数一致通过。
该提案由加州环境保护署(Cal/ EPA)辖下的环境健康危害评估机构(OEHHA) 执行。
提案规定，从事买卖的个体，其雇员人数达10个或10个以上的（另有豁免的除外），须在含已获知可致癌或生殖毒性的化学物质的产品上贴上清晰﹑合理的警告标签，以避免与人体接触，且不得将该等化学物质排放到饮用水中。
消费品警告可直接置于产品标签上，也可置于店面产品附近的显眼处（参照表1）。
表1 警告标签典型示例警告示例1 2WARNING: This product contains a chemical known to the State of California to causecancer W ARNING: This product contains a chemical known to the State of California to cause birth defects or other reproductive harm第65号提案列出了大约800种已被加州当局确定为致癌性或生殖毒性的化学物清单。
该类化学物质清单包括大量自然产生的和人工合成的化学物质，包括用于杀虫剂﹑普通家用产品﹑食品﹑药物﹑染料或溶剂的添加剂或配料。
它们可用于制造业和建造业，也可以是化学过程的副产品，如机动车尾气。
所列化学物质包括烟草烟雾﹑金属（例如：铅﹑镉和镍）和有机化学物质（例如邻苯二甲酸盐：BBP﹑DBP﹑DEHP﹑DIDP﹑DnHP等，及多环芳香烃：苯并芘等）。
california proposition 65 list标准原文
美国加州pro65标准
美国加州Pro65标准引言美国加州是世界上最繁忙的经济地区之一，拥有庞大的人口和复杂的产业体系。
为确保消费者和环境的安全，加州制定了严格的标准和法规，其中之一就是Pro65标准。
本文将详细介绍美国加州Pro65标准，包括其背景、适用范围、标准要求以及对企业的影响和责任。
背景Pro65标准，也被称为加州65号议案，是由加州议会于1986年通过的一项法案，旨在提供关于需警告的化学物质清单，并要求对这些化学物质进行标签警告。
该法案的正式名称为《加州安全饮用水和有害化学物清单法案》（Safe Drinking Water and Toxic Enforcement Act of 1986）。
根据该法案，在加州销售的产品中，如果含有在清单上列出的有害化学物质且超过一定的浓度阈值，就必须在产品上标明警告。
适用范围Pro65标准适用于在加州销售的所有产品，包括但不限于食品、饮料、家具、汽车、电子产品等。
不论是生产、进口还是销售这些产品的企业都需要遵守该标准。
尽管Pro65标准只在加州生效，但由于加州市场的重要性和影响力，很多企业都会将此标准作为全球性的参考。
标准要求Pro65标准要求企业对清单上的化学物质进行风险评估，并在产品上进行警告。
以下是Pro65标准的主要要求：1.清单披露要求：企业需要对其产品进行测试，以确定是否存在超过浓度阈值的有害化学物质。
如果存在，企业必须在产品上标明警告。
2.警告标签要求：警告标签必须清楚、明显地显示在产品上或者产品的包装上。
标签中必须包含清晰的描述，说明产品可能包含的有害化学物质和相关的健康风险。
3.警告语言要求：Pro65标准规定了一些标准化的警告语言，企业应使用这些警告语言在产品上标明警告。
例如：。
加州第65号提案 英文官方说明
Proposition 65 in Plain LanguageWhat is Proposition 65?In 1986, California voters approved an initiative to address their growing concerns about exposure to toxic chemicals. That initiative became the Safe Drinking Water and Toxic Enforcement Act of 1986, better known by its original name of Proposition 65.Proposition 65 requires the State to publish a list of chemicals known to cause cancer or birth defects or other reproductive harm. This list, which must be updated at least oncea year, has grown to include over 800 chemicals since it was first published in 1987. Proposition 65 requires businesses to notify Californians about significant amounts of chemicals in the products they purchase, in their homes or workplaces, or that arereleased into the environment. By providing this information, Proposition 65 enables Californians to make informed decisions about protecting themselves from exposure tothese chemicals. Proposition 65 also prohibits California businesses from knowingly discharging significant amounts of listed chemicals into sources of drinking water.The Office of Environmental Health Hazard Assessment (OEHHA) administers the Proposition 65 program. OEHHA, which is part of the California EnvironmentalProtection Agency (Cal/EPA), also evaluates all currently available scientific informationon substances considered for placement on the Proposition 65 list.What types of chemicals are on the Proposition 65 list?The list contains a wide range of naturally occurring and synthetic chemicals that areknown to cause cancer or birth defects or other reproductive harm. These chemicalsinclude additives or ingredients in pesticides, common household products, food, drugs, dyes, or solvents. Listed chemicals may also be used in manufacturing andconstruction, or they may be byproducts of chemical processes, such as motor vehicle exhaust.How is a chemical added to the list?There are four principal ways for a chemical to be added to the Proposition 65 list. A chemical can be listed if either of two independent committees of scientists and health professionals finds that the chemical has been clearly shown to cause cancer or birth defects or other reproductive harm. These two committees—the CarcinogenIdentification Committee (CIC) and the Developmental and Reproductive Toxicant (DART) Identification Committee—are part of OEHHA’s Science Advisory Board. Thecommittee members are appointed by the Governor and are designated as the “State’s Qualified Experts” for evaluating chemicals under Proposition 65. When determining whether a chemical should be placed on the list, the committees base their decisions on the most current scientific information available. OEHHA staff scientists compile all relevant scientific evidence on various chemicals for the committees to review. The committees also consider comments from the public before making their decisions.A second way for a chemical to be listed is if an organization designated as an "authoritative body" by the CIC or DART Identification Committee has identified it as causing cancer or birth defects or other reproductive harm. The following organizations have been designated as authoritative bodies: the U.S. Environmental Protection Agency, U.S. Food and Drug Administration (U.S. FDA), National Institute for Occupational Safety and Health, National Toxicology Program, and International Agency for Research on Cancer.A third way for a chemical to be listed is if an agency of the state or federal government requires that it be labeled or identified as causing cancer or birth defects or other reproductive harm. Most chemicals listed in this manner are prescription drugs that are required by the U.S. FDA to contain warnings relating to cancer or birth defects or other reproductive harm.A fourth way requires the listing of chemicals meeting certain scientific criteria and identified in the California Labor Code as causing cancer or birth defects or other reproductive harm. This method established the initial chemical list following voter approval of Proposition 65 in 1986 and continues to be used as a basis for listing as appropriate.What requirements does Proposition 65 place on companies doing business in California?Businesses are required to provide a "clear and reasonable" warning before knowingly and intentionally exposing anyone to a listed chemical. This warning can be given by a variety of means, such as by labeling a consumer product, posting signs at the workplace, distributing notices at a rental housing complex, or publishing notices in a newspaper. Once a chemical is listed, businesses have 12 months to comply with warning requirements.Proposition 65 also prohibits companies that do business within California from knowingly discharging listed chemicals into sources of drinking water. Once a chemical is listed, businesses have 20 months to comply with the discharge prohibition. Businesses with less than 10 employees and government agencies are exempt from Proposition 65’s warning requirements and prohibition on discharges into drinking water sources. Businesses are also exempt from the warning requirement and discharge prohibition if the exposures they cause are so low as to create no significant risk of cancer or birth defects or other reproductive harm. Health risks are explained in more detail below.What does a warning mean?If a warning is placed on a product label or posted or distributed at the workplace, a business, or in rental housing, the business issuing the warning is aware or believesthat one or more listed chemicals is present. By law, a warning must be given for listed chemicals unless exposure is low enough to pose no significant risk of cancer or is significantly below levels observed to cause birth defects or other reproductive harm. For chemicals that are listed as causing cancer, the "no significant risk level” is defined as the level of exposure that would result in not more than one excess case of cancer in 100,000 individuals exposed to the chemical over a 70-year lifetime. In other words, a person exposed to the chemical at the “no significant risk level” for 70 years would not have more than a “one in 100,000” chance of developing cancer as a result of that exposure.For chemicals that are listed as causing birth defects or reproductive harm, the “no observable effect level” is determined by identifying the level of exposure that has been shown to not pose any harm to humans or laboratory animals. Proposition 65 then requires this “no observable effect level” to be divided by 1,000 in order to provide an ample margin of safety. Businesses subject to Proposition 65 are required to provide a warning if they cause exposures to chemicals listed as causing birth defects or reproductive harm that exceed 1/1000th of the “no observable effect level.”To further assist businesses, OEHHA develops numerical guidance levels, known as “safe harbor numbers” (described below) for determining whether a warning is necessary or whether discharges of a chemical into drinking water sources are prohibited. However, a business may choose to provide a warning simply based on its knowledge, or assumption, about the presence of a listed chemical without attempting to evaluate the levels of exposure. Because businesses do not file reports with OEHHA regarding what warnings they have issued and why, OEHHA is not able to provide further information about any particular warning. The business issuing the warning should be contacted for specific information, such as what chemicals are present, and at what levels, as well as how exposure to them may occur.What are safe harbor levels?As stated above, to guide businesses in determining whether a warning is necessary or whether discharges of a chemical into drinking water sources are prohibited, OEHHA has developed safe harbor levels. A business has “safe harbor” from Proposition 65 warning requirements or discharge prohibitions if exposure to a chemical occurs at or below these levels. These safe harbor levels consist of No Significant Risk Levels for chemicals listed as causing cancer and Maximum Allowable Dose Levels for chemicals listed as causing birth defects or other reproductive harm. OEHHA has established over 300 safe harbor levels to date and continues to develop more levels for listed chemicals.What if there is no safe harbor level?If there is no safe harbor level for a chemical, businesses that expose individuals to that chemical would be required to provide a Proposition 65 warning, unless the business can show that the anticipated exposure level will not pose a significant risk of cancer or reproductive harm. OEHHA has adopted regulations that provide guidance for calculating a level in the absence of a safe harbor level. Regulations are available atArticle 7 and Article 8 of Title 27, California Code of Regulations. Determining anticipated levels of exposure to listed chemicals can be very complex. Although a business has the burden of proving a warning is not required, a business is discouraged from providing a warning that is not necessary and instead should consider consulting a qualified professional if it believes an exposure to a listed chemical may not require a Proposition 65 warning.Who enforces Proposition 65?The California Attorney General’s Office enforces Proposition 65. Any district attorney or city attorney (for cities whose population exceeds 750,000) may also enforce Proposition 65. In addition, any individual acting in the public interest may enforce Proposition 65 by filing a lawsuit against a business alleged to be in violation of this law. Lawsuits have been filed by the Attorney General’s Office, district attorneys, consumer advocacy groups, and private citizens and law firms. Penalties for violatingProposition 65 by failing to provide notices can be as high as $2,500 per violation per day.How is Proposition 65 meeting its goal of reducing exposure to hazardous chemicals in California?Since it was passed in 1986, Proposition 65 has provided Californians with information they can use to reduce their exposures to listed chemicals that may not have been adequately controlled under other State or federal laws. This law has also increased public awareness about the adverse effects of exposures to listed chemicals. For example, Proposition 65 has resulted in greater awareness of the dangers of alcoholic beverage consumption during pregnancy. Alcohol consumption warnings are perhaps the most visible health warnings issued as a result of Proposition 65.Proposition 65’s warning requirement has provided an incentive for manufacturers to remove listed chemicals from their products. For example, trichloroethylene, which causes cancer, is no longer used in most correction fluids; reformulated paint strippers do not contain the carcinogen methylene chloride; and toluene, which causes birth defects or other reproductive harm, has been removed from many nail care products. In addition, a Proposition 65 enforcement action prompted manufacturers to decrease the lead content in ceramic tableware and wineries to eliminate the use of lead-containing foil caps on wine bottles.Proposition 65 has also succeeded in spurring significant reductions in California of air emissions of listed chemicals, such as ethylene oxide, hexavalent chromium, and chloroform.Although Proposition 65 has benefited Californians, it has come at a cost for companies doing business in the state. They have incurred expenses to test products, develop alternatives to listed chemicals, reduce discharges, provide warnings, and otherwise comply with this law. Recognizing that compliance with Proposition 65 comes at a price, OEHHA is working to make the law’s regulatory requirements as clear as possible and ensure that chemicals are listed in accordance with rigorous science in an open public process.Where can I get more information on Proposition 65?For general information on the Proposition 65 list of chemicals, you may contact OEHHA’s Proposition 65 program at (916) 445-6900, or visit/prop65.html . For enforcement information, contact the California Attorney General’s Office at (510) 873-6321, or visit /prop65.Updated February 2013。
美国加州65标准
美国加州65标准美国加州65标准（California Proposition 65）是指一项旨在保护加州居民免受化学品毒害的法律要求。
该标准要求在加州销售或分发的产品中，如果含有被认定为可能导致癌症、生殖毒性或其他严重健康危害的化学物质，必须在产品上明确标示警示信息。
这项法律已经成为全球化学品管理的重要标杆，对于进入美国市场的产品生产商和供应商来说，遵守加州65标准是必不可少的。
加州65标准的实施对产品生产商和供应商提出了严格的要求。
首先，他们需要对产品中所含化学物质进行全面的检测和分析，确保产品不含被列入加州65标准的化学品清单中的有害物质。
其次，如果产品中的化学物质含量超过了加州65标准规定的安全浓度，生产商和供应商需要在产品标签上明确标示相关的警示信息，告知消费者潜在的健康风险。
此外，生产商和供应商还需要向加州政府提交有关产品中化学物质的报告，以便加州政府对产品进行监管和管理。
对于产品生产商和供应商来说，遵守加州65标准意味着需要投入更多的人力、物力和财力来进行产品的化学成分分析和监测。
同时，他们还需要制定更严格的供应链管理措施，确保从原材料采购到产品销售的每一个环节都符合加州65标准的要求。
这无疑会增加企业的成本和管理负担，但从长远来看，遵守加州65标准有助于提升企业的社会责任形象，保护消费者的健康权益，提升产品的市场竞争力。
对于消费者来说，加州65标准的实施意味着他们能够更清晰地了解到所购买产品的潜在健康风险。
产品标签上的警示信息能够帮助消费者在购买时做出理性的决策，避免接触可能有害的化学物质。
同时，加州65标准的实施也督促了产品生产商和供应商加强对产品质量和安全的管理，提升了产品的整体品质和安全性，从而保障了消费者的健康权益。
总的来说，美国加州65标准的实施对于化学品管理和产品质量安全意义重大。
它不仅促进了化学品生产和销售的规范化和标准化，也提升了消费者对产品安全的信心和保障。
因此，无论是产品生产商、供应商还是消费者，都应该认真遵守加州65标准的要求，共同维护好产品质量和消费者健康权益。
加州65宣告书(中英文)
California Proposition 65 Declaration加州65宣告書California's Safe Drinking Water and Toxic Enforcement Act of 1986 (known as "Prop 65"), seeks to ensure that individuals in California are informed about exposure to chemicals known by the State to cause cancer and/or reproductive harm. To comply, businesses are required to provide a clear and reasonable warning before exposing anyone to a listed chemical. In late 2016, the State of California amended the warning language and methods that are deemed "clear and reasonable" under the statute. These amendments become effective on August 30, 2018.加州1986年的“安全飲用水和有毒物質強制法案”(稱為“第65號提案”)，要求該州公佈已知會造成癌症、先天性缺陷及其它生殖傷害的化學物質清單。
為了遵守規定，企業必須在將任何人暴露於所列化學品之前能提供警告標示。
2016年底，美國加州OEHHA修改了根據法規被視為“明確和合理”的警告語言和方法，這些修正案於2018年8月30日生效。
This declaration is to inform XXX at products manufactured by (Company Name) do not contain chemicals which are listed on California’s Safe Drinking Water & Toxic Enforcement Act of 1986. This Act, commonly known as Proposition 65 (Prop 65), establishes a list of chemicals which the state of California’s risk assessment process has determined to present a risk of cancer, birth defects or other reproductive harm. 此宣告書在通知，(公司名稱) 生產的產品不含加州1986年安全飲用水和有毒執法法案中列出的化學品。
美国加州65号提案(详细说明书)
2015-08-03 14:42:28加州65更新有害物质管控清单背景介绍加州65号提案即《1986年饮用水安全与毒性物质强制执行法》，1986年11月颁发，其宗旨是保护美国加州居民及该州的饮用水水源，使水源不含已知可能导致癌症、出生缺陷或其他生殖发育危害的物质，并在产品出现该类物质时如实通知居民。
加州65管控物质清单由OEHHA出台并每季度更新，首次出版于1987年，最新清单中物质已达900多种。
核心管控要求1、禁止引用水源污染：任何人在经营过程中不得有意排放或释放加州所知的致癌性或有生殖毒性的物质进入水源或投放到可能污染水源的土地上或土地中。
2、警示要求：某一种化学物质被列入管控清单后，制造商和经销商须在12个月内完成警告的执行，在20个月内终止化学物质排放至饮用水源头。
此日期过后，政府或个人执法者，包括代表公众利益的个人或组织，可对违反法规者提起诉讼。
3、有害物质限量要求：加州65法案管控清单本身并未对物质设定限值，产品中有害物质的管控限值，参考已有的针对此类产品的诉讼案或协议，这些文件中，可能会达成针对某类产品中某些物质的限值要求以及测试方法。
4、企业在进行加州65管控时，首先应比对已有的此类产品的诉讼案中确定的物质管控要求，然后参考此管控来调查产品中的有害物质。
CTI建议加州65本身并未规定具体管控产品类别，但是由于法案制定的目的是为了避免有害物质进入加州水源，所以，理论上来说，一切含有有害物质的产品都在其管控范围内，企业可以关注法规新增加的以及高风险的化学物质。
展开供应链调查，必要时可以进行检测，以降低产品违规风险。
2015-11-16 15:09:12加州65欲添加五氯苯酚类物质到有害物质清单背景介绍1986年11月，加利福尼亚州颁布《1986年饮用水安全与毒性物质强制执行法》，即美国加利福尼亚州关于增加对可接触的有毒化学物质关注的提案，简称“加州65提案”。
后被编纂列入加利福尼亚州健康和安全法典的25249.5 -25249.13 章。
加州65环保标准
加州65环保标准
加州65环保标准是美国加利福尼亚州环境保护局（California EPA）针对在加
利福尼亚州发售的汽车发动机及柴油机及零配件等产品，制定的有关环境污染排
放标准。
该标准正式实施于2003年7月，其主要内容如下：
一、排放物标准
1、燃油排放：加州65环保标准要求汽油机和柴油机要实现低氮氧化物(NOx)和一
氧化氮(Nox)排放控制标准；
2、发动机燃料中硫成：要求汽油和柴油燃料中硫含量相应降低；
3、碳排放：要求发动机的CO、HC、NOx的排放比例必须控制在特定范围；
4、噪音标准：要求发动机的噪音不能大于规定范围；
二、废气检测标准
加州65环保标准基于椭圆管抽样（EVAP）技术，在off-highway engines和vehicular engines上开发了多种检测仪器，以检测废气中的一氧化碳、氮氧化物、
碳氢化合物等有害物质的排放情况，以确定发动机是否符合环保要求。
三、监测与报告责任
为了确保发动机满足加州65环保标准的要求，发动机的制造商、销售商和使用单
位必须完成废气检测，并由美国加州环境保护局（CEP）指定的认可机构进行检测，并准备完整的报告。
随后，受影响的部门（厂商、代理商、用户）都需要向CEP
局提交他们最近检查的报告副本以及污染浓度最大值的标准测量报告。
以上就是加州65环保标准的内容。
此标准对于禁止有害污染物流失具有十分
重要的作用，对于维护地球家园至关重要。
加州65法案
SAFE DRINKING WATER AND TOXIC ENFORCEMENT ACT OF 1986(Chapter 6.6 added by Proposition 65 1986 General Election)25249.5. Prohibition On Contaminating Drinking Water With Chemicals Known to Cause Cancer or Reproductive Toxicity. No person in the course of doing business shall knowingly discharge or release a chemical known to the state to cause cancer or reproductive toxicity into water or onto or into land where such chemical passes or probably will pass into any source of drinking water, notwithstanding any other provision or authorization of law except as provided in Section 25249.9.25249.6. Required Warning Before Exposure To Chemicals Known to Cause Cancer Or Reproductive Toxicity. No person in the course of doing business shall knowingly and intentionally expose any individual to a chemical known to the state to cause cancer or reproductive toxicity without first giving clear and reasonable warning to such individual, except as provided in Section 25249.10.25249.7. Enforcement.(a) Any person that violates or threatens to violate Section 25249.5 or 25249.6 may be enjoined in any court of competent jurisdiction.(b) (1) Any person who has violated Section 25249.5 or 25249.6 shall be liable for acivil penalty not to exceed two thousand five hundred dollars ($2500) per day for each violation in addition to any other penalty established by law. That civil penalty may be assessed and recovered in a civil action brought in any court of competent jurisdiction.(2) In assessing the amount of a civil penalty for a violation of this chapter, thecourt shall consider all of the following:(A) The nature and extent of the violation.(B) The number of, and severity of, the violations.(C) The economic effect of the penalty on the violator.(D) Whether the violator took good faith measures to comply with thischapter and the time these measures were taken.(E) The willfulness of the violator’s misconduct.(F) The deterrent effect that the imposition of the penalty would have onboth the violator and the regulated community as a whole.(G) Any other factor that justice may require.(c) Actions pursuant to this section may be brought by the Attorney General in the nameof the people of the State of California, by any district attorney, by any city attorney of a city having a population in excess of 750,000, or, with the consent of the district attorney, by a city prosecutor in any city or city and county having a full-time city prosecutor, or as provided in subdivision (d).(d) Actions pursuant to this section may be brought by any person in the public interestif both of the following requirements are met:(1) The private action is commenced more than 60 days from the date that theperson has given notice of an alleged violation of Section 25249.5 or 25249.6 that is the subject of the private action to the Attorney General and the district attorney, city attorney, or prosecutor in whose jurisdiction the violation is alleged to have occurred, and to the alleged violator. If the notice alleges a violation of Section 25249.6, the notice of the alleged violation shall include a -2-certificate of merit executed by the attorney for the noticing party, or by the noticing party, if the noticing party is not represented by an attorney. The certificate of merit shall state that the person executing the certificate has consulted with one or more persons with relevant and appropriate experience or expertise who has reviewed facts, studies, or other data regarding the exposure to the listed chemical that is the subject of the action, and that, based on that information, the person executing the certificate believes there is a reasonable and meritoriouscase for the private action. Factual information sufficient to establish the basis of the certificate of merit, including the information identified in paragraph (2) of subdivision (h), shall be attached to the certificate of merit that is served on the Attorney General.(2) Neither the Attorney General, any district attorney, any city attorney nor anyprosecutor has commenced and is diligently prosecuting an action against the violation.(e) Any person bringing an action in the public interest pursuant to subdivision (d) andany person filing any action in which a violation of this chapter is alleged shall notify the Attorney General that the action has been filed. Neither this subdivision nor the procedures provided in subdivisions (f) to (j), inclusive, shall affect the requirements imposed by the statute or a court decision in existence on January 1, 2002 concerning whether any person filing any action in which a violation of this chapter is alleged is required to comply with the requirements of subdivision (d).(f) (1) Any person bringing an action in the public interest pursuant to subdivision (d),any person filing any action in which a violation of this chapter is alleged, or any private person settling any violation of this chapter alleged in a notice given pursuant to paragraph (1) of subdivision (d), shall, after the action or violation is either subject to a settlement or to a judgment, submit to the Attorney General a reporting form that includes the results of that settlement or judgment and the final disposition of the case, even if dismissed. At the time of the filing of any judgment pursuant to an action brought in the public interest pursuant to subdivision (d), or any action brought by a private person in which a violation of this chapter is alleged, the plaintiff shall file an affidavit verifying that the report required by this subdivision has been accurately completed and submitted to the Attorney General.(2) Any person bringing an action in the public interest pursuant to subdivision(d) or any private person bringing an action in which a violation of this chapter is alleged, shall, after the action is either subject to a settlement, with or without court approval, or to a judgment, submit to the Attorney General a report that includes information on any corrective action being taken as a part of the settlement or resolution of the action.(3) The Attorney General shall develop a reporting form that specifies theinformation that shall be reported, including, but not limited to, for purposes of subdivision (e), the date the action was filed, the nature of the relief sought, and for purposes of this subdivision, the amount of the settlement or civil penalty assessed, other financial terms of the settlement, and any other information the Attorney General deems appropriate.(4) If there is a settlement of an action brought by a person in the public interestunder subdivision (d), the plaintiff shall submit the settlement, other than a voluntary dismissal in which no consideration is received from the defendant, to the court for approval upon noticed motion, and the court may approve the settlement only if the court makes all of the following findings:(A) Any warning that is required by the settlement complies with thischapter.(B) Any award of attorney’s fees is reasonable under California l aw.-3-(C) Any penalty amount is reasonable based on the criteria set forth inparagraph (2) of subdivision (b).(5) The plaintiff subject to paragraph (4) has the burden of producing evidencesufficient to sustain each required finding. The plaintiff shall serve the motion and all supporting papers on the Attorney General, who may appear and participate in any proceeding without intervening in the case.(6) Neither this subdivision nor the procedures provided in subdivision (e) andsubdivisions (g) to (j), inclusive, shall affect the requirements imposed by statute or a court decision in existence on the January 1, 2002 concerning whether claims raised by any person orpublic prosecutor not a party to the action are precluded by a settlement approved by the court.(g) The Attorney General shall maintain a record of the information submitted pursuantto subdivisions (e) and (f) and shall make this information available to the public.(h) (1) Except as provided in paragraph (2), the basis for the certificate of merit requiredby subdivision (d) is not discoverable. However, nothing in this subdivision shall preclude the discovery of information related to the certificate of merit if that information is relevant to the subject matter of the action and is otherwise discoverable, solely on the ground that it was used in support of the certificate of merit.(2) Upon the conclusion of an action brought pursuant to subdivision (d) withrespect to any defendant, if the trial court determines that there was no actual or threatened exposure to a listed chemical, the court may, upon the motion of that alleged violator or upon the court’s own motion, review the basis for the belief of the person executing the certificate of merit, expressed in the certificate of merit, that an exposure to a listed chemical had occurred or was threatened. The information in the certificate of merit, including the identity of the persons consulted with and relied on by the certifier, and the facts, studies, or other data reviewed by those persons, shall be disclosed to the court in an in-camera proceeding at which the moving party shall not be present. If the court finds that there was no credible factual basis for the certifier’s belief that an exposure to a listed chemical has occurred or was threatened, then the action shall be deemed frivolous within the meaning of Section 128.6 or 128.7 of the Code of Civil Procedure, whichever provision is applicable to the action. The court shall not find a factual basis credible on the basis of a legal theory of liability that is frivolous within the meaning of Section 128.6 or 128.7 of the Code of Civil Procedure, whichever provision is applicable to the action.(i) The Attorney General may provide the factual information submitted to establish thebasis of the certificate of merit on request to any district attorney, city attorney, or prosecutor within whose jurisdiction the violation is alleged to have occurred, or to any other state or federal government agency, but in all other respects the Attorney General shall maintain, and ensure that all recipients maintain, the submitted information as confidential official information to the full extent authorized in Section 1040 of the Evidence Code.(j) In any action brought by the Attorney General, a district attorney, a city attorney, or a prosecutor pursuant to this chapter, the Attorney General, district attorney, city attorney, or prosecutor may seek and recover costs and attorney’s fees on behalf of any party who provides a notice pursuant to subdivision (d) and who renders assistance in that action.25249.8. List Of Chemicals Known to Cause Cancer Or Reproductive Toxicity.(a) On or before March 1, 1987, the Governor shall cause to be published a list of those chemicals known to the state to cause cancer or reproductive toxicity within the meaning of this -4-chapter, and he shall cause such list to be revised and republished in light of additional knowledge at least once per year thereafter. Such list shall include at a minimum those substances identified by reference in Labor Code Section 6382(b)(1) and those substances identified additionally by reference in Labor Code Section 6382(d).(b) A chemical is known to the state to cause cancer or reproductive toxicity within the meaning of this chapter if in the opinion of the state's qualified experts it has been clearly shown through scientifically valid testing according to generally accepted principles to cause cancer or reproductive toxicity, or if a body considered to be authoritative by such experts has formally identified it as causing cancer or reproductive toxicity, or if an agency of the state or federal government has formally required it to be labeled or identified as causing cancer or reproductive toxicity.(c) On or before January 1, 1989, and at least once per year thereafter, the Governorshall cause to be published a separate list of those chemicals that at the time of publication arerequired by state or federal law to have been tested for potential to cause cancer or reproductive toxicity but that the state's qualified experts have not found to have been adequately tested as required.(d) The Governor shall identify and consult with the state's qualified experts asnecessary to carry out his duties under this section.(e) In carrying out the duties of the Governor under this section, the Governor and his designates shall not be considered to be adopting or amending a regulation within the meaning of the Administrative Procedure Act as defined in Government Code Section 11370.25249.9. Exemptions from Discharge Prohibition.(a) Section 25249.5 shall not apply to any discharge or release that takes places less than twenty months subsequent to the listing of the chemical in question on the list required to be published under subdivision (a) of Section 25249.8.(b) Section 25249.5 shall not apply to any discharge or release that meets both of the following criteria:(1) The discharge or release will not cause any significant amount of thedischarged or released chemical to enter any source of drinking water.(2) The discharge or release is in conformity with all other laws and with everyapplicable regulation, permit, requirement, and order. In any action brought to enforce Section 25249.5, the burden of showing that a discharge or release meets the criteria of this subdivision shall be on the defendant.25249.10. Exemptions from Warning Requirement. Section 25249.6 shall not apply to any of the following:(a) An exposure for which federal law governs warning in a manner that preempts state authority.(b) An exposure that takes place less than twelve months subsequent to the listing of the chemical in question on the list required to be published under subdivision (a) ofSection 25249.8.(c) An exposure for which the person responsible can show that the exposure poses no significant risk assuming lifetime exposure at the level in question for substances known to the state to cause cancer, and that the exposure will have no observable effect assuming exposure at one thousand (1000) times the level in question for substances known to the state to cause-5-reproductive toxicity, based on evidence and standards of comparable scientific validity to the evidence and standards which form the scientific basis for the listing of such chemical pursuant to subdivision (a) of Section 25249.8. In any action brought to enforce Section 25249.6, the burden of showing that an exposure meets the criteria of this subdivision shall be on the defendant.25249.11. Definitions. For purposes of this chapter:(a) "Person" means an individual, trust, firm, joint stock company, corporation,company, partnership, limited liability company, and association.(b) "Person in the course of doing business" does not include any person employingfewer than 10 employees in his or her business; any city, county, or district or any department or agency thereof or the state or any department or agency thereof or the federal government or any department or agency thereof; or any entity in its operation of a public water system as defined in Section 4010.1.(c) "Significant amount" means any detectable amount except an amount which wouldmeet the exemption test in subdivision (c) of Section 25249.10 if an individual were exposed to such an amount in drinking water.(d) "Source of drinking water" means either a present source of drinking water or waterwhich is identified or designated in a water quality control plan adopted by a regional board asbeing suitable for domestic or municipal uses.(e) "Threaten to violate" means to create a condition in which there is a substantial probability that a violation will occur.(f) "Warning" within the meaning of Section 25249.6 need not be provided separately toeach exposed individual and may be provided by general methods such as labels on consumer products, inclusion of notices in mailings to water customers, posting of notices, placing notices in public news media, and the like, provided that the warning accomplished is clear and reasonable. In order to minimize the burden on retail sellers of consumer products including foods, regulations implementing Section 25249.6 shall to the extent practicable place the obligation to provide any warning materials such as labels on the producer or packager rather than on the retail seller, except where the retail seller itself is responsible for introducing a chemical known to the state to cause cancer or reproductive toxicity into the consumer product in question.25249.12. (a) The Governor shall designate a lead agency and other agencies that may be required to implement this chapter, including this section. Each agency so designated may adopt and modify regulations, standards, and permits as necessary to conform with and implement this chapter and to further its purposes.(b) The Safe Drinking Water and Toxic Enforcement Fund is hereby established in theState Treasury. The director of the lead agency designated by the Governor to implement this chapter may expend the funds in the Safe Drinking Water and Toxic Enforcement Fund, upon appropriation by the Legislature, to implement and administer this chapter.(c) In addition to any other money that may be deposited in the Safe Drinking Water and Toxic Enforcement Fund, all of the following amounts shall be deposited in the fund:(1) Seventy-five percent of all civil and criminal penalties collected pursuant tothis chapter.-6-(2) Any interest earned upon the money deposited into the Safe Drinking Waterand Toxic Enforcement Fund.(d) Twenty-five percent of all civil and criminal penalties collected pursuant to thischapter shall be paid to the office of the city attorney, city prosecutor, district attorney, or Attorney General, whichever office brought the action, or in the case of an action brought by a person under subdivision (d) of Section 25249.7, to that person.25249.13. Preservation Of Existing Rights, Obligations, and Penalties. Nothing in this chapter shall alter or diminish any legal obligation otherwise required in common law or by statute or regulation, and nothing in this chapter shall create or enlarge any defense in any action to enforce such legal obligation. Penalties and sanctions imposed under this chapter shall be in addition to any penalties or sanctions otherwise prescribed by law.25180.7. (a) Within the meaning of this section, a "designated government employee" is any person defined as a "designated employee" by Government Code Section 82019, as amended.(b) Any designated government employee who obtains information in the course of hisofficial duties revealing the illegal discharge or threatened illegal discharge of a hazardous waste within the geographical area of his jurisdiction and who knows that such discharge or threatened discharge is likely to cause substantial injury to the public health or safety must, within seventytwohours, disclose such information to the local Board of Supervisors and to the local health officer. No disclosure of information is required under this subdivision when otherwise prohibited by law, or when law enforcement personnel have determined that such disclosure would adversely affect an ongoing criminal investigation, or when the information is already general public knowledge within the locality affected by the discharge or threatened discharge.(c) Any designated government employee who knowingly and intentionally fails todisclose information required to be disclosed under subdivision (b) shall, upon conviction, be punished by imprisonment in the county jail for not more than one year or by imprisonment in state prison for not more than three years. The court may also impose upon the person a fine of not less than five thousand dollars ($5000) or more than twenty-five thousand dollars ($25,000). The felony conviction for violation of this section shall require forfeiture of government employment within thirty days of conviction.(d) Any local health officer who receives information pursuant to subdivision (b) shalltake appropriate action to notify local news media and shall make such information available to the public without delay.25192. (a) All civil and criminal penalties collected pursuant to this chapter shall be apportioned in the following manner:(1) Fifty percent shall be deposited in the Hazardous Substance Account in theGeneral Fund.(2) Twenty-five percent shall be paid to the office of the city attorney, cityprosecutor, district attorney, or Attorney General, whichever office brought the action.(3) Twenty-five percent shall be paid to the department and used to fund theactivity of the CUPA, the local health officer, or other local public officer or agency authorizedto enforce the provisions of this chapter pursuant to Section 25180, whichever entity investigated the matter that led to the bringing of the action. If investigation by the local police department or sheriff's office or California Highway Patrol led to the bringing of the action, the CUPA, the-7-local health officer, or the authorized officer or agency, shall pay a total of 40 percent of its portion under this subdivision to that investigating agency or agencies to be used for the same purpose. If more than one agency is eligible for payment under this paragraph, division of payment among the eligible agencies shall be in the discretion of the CUPA, the local health officer, or the authorized officer or agency.(b) If a reward is paid to a person pursuant to Section 25191.7, the amount of the reward shall be deducted from the amount of the civil penalty before the amount is apportioned pursuant to subdivision (a).。
美国加州65规范
美国加州65标准（CP65）proposition 65加州第65号提案从颁布到现在已有20余年，一直秉持减少有毒化学物质的暴露的宗旨。
它允许加州居民通过一定的方式消除消费品和工业中的致癌物质和生殖毒性化学物质的行为。
自第65号提案制定以来，众多关于消费品中含有毒化学物质诉讼案在加州不断出现，从而引领整个美国一系列的限制标准的实施。
第65号提案，即《加州安全饮用水和有毒物执行法》，于1986 年11 月经加州居民投票，以压倒性的票数一致通过。
该提案由加州环境保护署(Cal/ EPA)辖下的环境健康危害评估机构(OEHHA) 执行。
提案规定，从事买卖的个体，其雇员人数达10个或10个以上的（另有豁免的除外），须在含已获知可致癌或生殖毒性的化学物质的产品上贴上清晰﹑合理的警告标签，以避免与人体接触，且不得将该等化学物质排放到饮用水中。
消费品警告可直接置于产品标签上，也可置于店面产品附近的显眼处（参照表1）。
表1 警告标签典型示例警告示例1 2WARNING: This product contains a chemical known to the State of California to cause cancer WARNING: This product contains a chemical known to the State of California to cause birth defects or other reproductive harm第65号提案列出了大约800种已被加州当局确定为致癌性或生殖毒性的化学物清单。
该类化学物质清单包括大量自然产生的和人工合成的化学物质，包括用于杀虫剂﹑普通家用产品﹑食品﹑药物﹑染料或溶剂的添加剂或配料。
它们可用于制造业和建造业，也可以是化学过程的副产品，如机动车尾气。
所列化学物质包括烟草烟雾﹑金属（例如：铅﹑镉和镍）和有机化学物质（例如邻苯二甲酸盐：BBP﹑DBP﹑ DEHP﹑DIDP﹑DnHP等，及多环芳香烃：苯并芘等）。
加州65宣告书（中英文）
加州65宣告书（中英文）California Proposition 65 Declaration加州65宣告書California's Safe Drinking Water and Toxic Enforcement Act of 1986 (known as "Prop 65"), seeks to ensure that individuals in California are informed about exposure to chemicals known by the State to cause cancer and/or reproductive harm. To comply, businesses are required to provide a clear and reasonable warning before exposing anyone to a listed chemical. In late 2016, the State of California amended the warning language and methods that are deemed "clear and reasonable" under the statute. These amendments become effective on August 30, 2018.加州1986年的“安全飲用水和有毒物質強制法案”(稱為“第65號提案”)，要求該州公佈已知會造成癌症、先天性缺陷及其它生殖傷害的化學物質清單。
為了遵守規定，企業必須在將任何人暴露於所列化學品之前能提供警告標示。
2016年底，美國加州OEHHA修改了根據法規被視為“明確和合理”的警告語言和方法，這些修正案於2018年8月30日生效。
This declaration is to inform XXX at products manufactured by (Company Name) do not contain chemicals which are listed on California’s Safe Drinking Water & Toxic Enforcement Act of 1986. This Act, commonly known as Proposition 65 (Prop 65), establishes a list of chemicals which the state of California’s risk assessment process has determined to present a risk of cancer, birth defects or other reproductive harm. 此宣告書在通知，(公司名稱) 生產的產品不含加州1986年安全飲用水和有毒執法法案中列出的化學品。
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STATE OF CALIFORNIAENVIRONMENTAL PROTECTION AGENCYOFFICE OF ENVIRONMENTAL HEALTH HAZARD ASSESSMENT SAFE DRINKING WATER AND TOXIC ENFORCEMENT ACT OF 1986CHEMICALS KNOWN TO THE STATE TO CAUSE CANCER OR REPRODUCTIVE TOXICITYJUNE 11, 2010The Safe Drinking Water and Toxic Enforcement Act of 1986 requires that the Governor revise and republish at least once per year the list of chemicals known to the State to cause cancer or reproductive toxicity. The identification number indicated in the following list is the ChemicalAbstracts Service (CAS) Registry Number. No CAS number is given when several substances are presented as a single listing. The date refers to the initial appearance of the chemical on the list. For easy reference, chemicals which are shown underlined are newly added. Chemicals or endpoints shown in strikeout were placed on the Proposition 65 list on the date noted, and have subsequently been removed.Chemical Type of Toxicity CAS No. Date Listed A-alpha-C (2-Amino-9H-pyrido [2,3-b]indole) cancer 26148-68-5 January 1, 1990 Acetaldehyde cancer 75-07-0 April 1, 1988 Acetamide cancer 60-35-5 January 1, 1990 Acetazolamide developmental 59-66-5 August 20, 1999 Acetochlor cancer 34256-82-1 January 1, 1989 Acetohydroxamic acid developmental 546-88-3 April 1, 1990 2-Acetylaminofluorene cancer 53-96-3 July 1, 1987 Acifluorfen sodium cancer 62476-59-9 January 1, 1990 Acrylamide cancer 79-06-1 January 1, 1990 Acrylonitrile cancer 107-13-1 July 1, 1987 Actinomycin D cancer 50-76-0 October 1, 1989 developmental October 1, 1992 AF-2;[2-(2-furyl)-3-(5-nitro-2-furyl)] acrylamide cancer 3688-53-7 July 1, 1987 Aflatoxins cancer --- January 1, 1988 Alachlor cancer 15972-60-8 January 1, 1989 Alcoholic beverages, when associated with alcohol abuse cancer --- July 1, 1988 Aldrin cancer 309-00-2 July 1, 1988 All-trans retinoic acid developmental 302-79-4 January 1, 1989 Allyl chloride Delisted October 29, 1999 cancer 107-05-1 January 1, 1990 Alprazolam developmental 28981-97-7 July 1, 1990 Altretamine developmental, male 645-05-6 August 20, 1999 Amantadine hydrochloride developmental 665-66-7 February 27, 2001 Amikacin sulfate developmental 39831-55-5 July 1, 1990 2-Aminoanthraquinone cancer 117-79-3 October 1, 1989 p -Aminoazobenzene cancer 60-09-3 January 1, 1990 o -Aminoazotoluene cancer 97-56-3 July 1, 19874-Aminobiphenyl (4-amino- diphenyl)cancer 92-67-1 February 27, 1987 1-Amino-2,4-dibromo- anthraquinonecancer 81-49-2 August 26, 1997 3-Amino-9-ethylcarbazole hydrochloride cancer 6109-97-3 July 1, 1989 2-Aminofluorene cancer153-78-6 January 29, 1999 Aminoglutethimide developmental 125-84-8 July 1, 1990 Aminoglycosidesdevelopmental ---October 1, 1992 1-Amino-2-methylanthraquinone cancer 82-28-0 October 1, 1989 2-Amino-5-(5-nitro-2-furyl)-1,3,4- thiadiazolecancer712-68-5 July 1, 1987 4-Amino-2-nitrophenol cancer119-34-6 January 29, 1999 Aminopterindevelopmental, female 54-62-6 July 1, 1987 Amiodarone hydrochloride developmental, female, male19774-82-4 August 26, 1997 Amitraz developmental 33089-61-1 March 30, 1999 Amitrole cancer61-82-5 July 1, 1987 Amoxapine developmental 14028-44-5 May 15, 1998 Amsacrinecancer51264-14-3 August 7, 2009tert-Amyl methyl ether developmental 994-05-8 December 18, 2009 Anabolic steroidsfemale, male --- April 1, 1990Analgesic mixtures containing phenacetincancer --- February 27, 1987 Angiotensin converting enzyme (ACE) inhibitors developmental --- October 1, 1992 Anilinecancer 62-53-3 January 1, 1990 Aniline hydrochloride cancer 142-04-1 May 15, 1998 o -Anisidinecancer 90-04-0 July 1, 1987 o -Anisidine hydrochloride cancer134-29-2 July 1, 1987 Anisindione developmental 117-37-3 October 1, 1992 Anthraquinonecancer 84-65-1 September 28, 2007 Antimony oxide (Antimony trioxide) cancer 1309-64-4 October 1, 1990 Aramite cancer 140-57-8 July 1, 1987Areca nutcancer --- February 3, 2006 Aristolochic acidscancer --- July 9, 2004Arsenic (inorganic arsenic compounds)cancer-- February 27, 1987 Arsenic (inorganic oxides) developmental ---May 1, 1997Asbestoscancer1332-21-4 February 27, 1987 Aspirin (NOTE: It is especially important not to use aspirin during the last three months of pregnancy, unless specifically directed to do so by a physician because it may cause problems in the unborn child orcomplications during delivery.) developmental, female50-78-2July 1, 1990Atenolol developmental 29122-68-7 August 26, 1997 Auramine cancer492-80-8 July 1, 1987Auranofin developmental 34031-32-8 January 29, 1999 Azacitidinecancer 320-67-2 January 1, 1992Azaserine cancer 115-02-6 July 1, 1987Azathioprine cancer446-86-6 February 27, 1987 Azathioprine developmental 446-86-6 September 1, 1996 Azobenzene cancer 103-33-3 January 1, 1990Barbituratesdevelopmental ---October 1, 1992 Beclomethasone dipropionate developmental5534-09-8 May 15, 1998 Benomyldevelopmental, male 17804-35-2 July 1, 1991 Benthiavalicarb-isopropyl cancer 177406-68-7 July 1, 2008 Benz[a]anthracene cancer 56-55-3 July 1, 1987Benzene cancer71-43-2 February 27, 1987 Benzenedevelopmental, male 71-43-2 December 26, 1997 Benzidine [and its salts] cancer 92-87-5 February 27, 1987 Benzidine-based dyes cancer--- October 1, 1992 Benzodiazepines developmental ---October 1, 1992 Benzo[b]fluoranthene cancer 205-99-2 July 1, 1987 Benzo[j]fluoranthene cancer 205-82-3 July 1, 1987 Benzo[k]fluoranthene cancer 207-08-9 July 1, 1987 Benzofuran cancer 271-89-6 October 1, 1990 Benzo[a]pyrene cancer 50-32-8 July 1, 1987 Benzotrichloridecancer98-07-7 July 1, 1987 Benzphetamine hydrochloride developmental 5411-22-3 April 1, 1990 Benzyl chloride cancer 100-44-7 January 1, 1990 Benzyl violet 4Bcancer 1694-09-3 July 1, 1987 Beryllium and beryllium compounds cancer --- October 1, 1987 Betel quid with tobacco cancer --- January 1, 1990 Betel quid without tobacco cancer ---February 3, 2006 2,2-Bis(bromomethyl)-1,3- propanediolcancer 3296-90-0 May 1, 1996 Bis(2-chloroethyl)ether cancer 111-44-4 April 1, 1988N,N-Bis(2-chloroethyl)-2-naphthylamine (Chlornapazine) cancer 494-03-1 February 27, 1987 Bischloroethyl nitrosourea (BCNU) (Carmustine)cancer 154-93-8 July 1, 1987 Bischloroethyl nitrosourea (BCNU) (Carmustine)developmental 154-93-8 July 1, 1990 Bis(chloromethyl)ethercancer 542-88-1 February 27, 1987 Bis(2-chloro-1-methylethyl)ether, technical gradecancer --- October 29, 1999 Bitumens, extracts of steam-refined and air refined cancer---January 1, 1990 Bracken ferncancer---January 1, 1990 Bromacil lithium salt developmental 53404-19-6 May 18, 1999 Bromacil lithium salt male 53404-19-6 January 17, 2003 Bromatecancer 15541-45-4 May 31, 2002 Bromochloroacetic acid cancer 5589-96-8 April 6, 2010 Bromodichloromethane cancer 75-27-4 January 1, 1990 Bromoethane cancer 74-96-4 December 22, 2000 Bromoformcancer75-25-2 April 1, 19911-Bromopropane (1-BP) developmental, female, male106-94-5 December 7, 2004 2-Bromopropane (2-BP)female, male75-26-3May 31, 2005Bromoxynildevelopmental 1689-84-5 October 1, 1990 Bromoxynil octanoate developmental 1689-99-2 May 18, 1999 Butabarbital sodium developmental 143-81-7 October 1, 1992 1,3-Butadiene cancer106-99-0 April 1, 1988 1,3-Butadienedevelopmental, female, male 106-99-0 April 16, 2004 1,4-Butanediol dimethanesulfonate (Busulfan)cancer 55-98-1 February 27, 1987 1,4-Butanediol dimethanesulfonate (Busulfan)developmental 55-98-1 January 1, 1989 Butylated hydroxyanisole cancer25013-16-5 January 1, 1990 Butyl benzyl phthalate (BBP) developmental 85-68-7 December 2, 2005 n-Butyl glycidyl ether male 2426-08-6 August 7, 2009 beta-Butyrolactone cancer 3068-88-0 July 1, 1987Cacodylic acid cancer75-60-5 May 1, 1996 Cadmiumdevelopmental, male --- May 1, 1997 Cadmium and cadmium compounds cancer--- October 1, 1987 Caffeic acid cancer 331-39-5 October 1, 1994 Captafol cancer 2425-06-1 October 1, 1988 Captancancer133-06-2 January 1, 1990 Carbamazepine developmental 298-46-4 January 29, 1999 Carbaryl cancer63-25-2 February 5, 2010 Carbaryl developmental, male 63-25-2 August 7, 2009 Carbazolecancer 86-74-8 May 1, 1996Carbon black (airborne, unbound particles of respirable size) cancer1333-86-4 February 21, 2003 Carbon disulfidedevelopmental, female, male75-15-0 July 1, 1989 Carbon monoxide developmental 630-08-0 July 1, 1989 Carbon tetrachloride cancer 56-23-5 October 1, 1987 Carbon-black extracts cancer---January 1, 1990 Carboplatindevelopmental 41575-94-4 July 1, 1990N-Carboxymethyl-N-nitrosourea cancer 60391-92-6 January 25, 2002 Catecholcancer 120-80-9 July 15, 2003 Ceramic fibers (airborne particles of respirable size)cancer --- July 1, 1990 Certain combined chemotherapy for lymphomas cancer --- February 27, 1987 Chenodiol developmental 474-25-9 April 1, 1990Chlorambucil cancer305-03-3 February 27, 1987 Chlorambucil developmental 305-03-3 January 1, 1989 Chloramphenicolcancer56-75-7 October 1, 1989 Chlorcyclizine hydrochloride developmental 1620-21-9 July 1, 1987 Chlordanecancer 57-74-9 July 1, 1988 Chlordecone (Kepone) cancer143-50-0 January 1, 1988 Chlordecone (Kepone) developmental 143-50-0 January 1, 1989 Chlordiazepoxidedevelopmental 58-25-3 January 1, 1992 Chlordiazepoxide hydrochloride developmental 438-41-5 January 1, 1992 Chlordimeform cancer 6164-98-3 January 1, 1989 Chlorendic acidcancer115-28-6July 1, 1989Chlorinated paraffins (Average chain length, C12; ap- proximately 60 percent chlorine by weight) cancer 108171-26-2 July 1, 1989p -Chloroanilinecancer 106-47-8 October 1, 1994 p -Chloroaniline hydrochloride cancer 20265-96-7 May 15, 1998 Chlorodibromomethane Delisted October 29, 1999 cancer 124-48-1 January 1, 1990 Chloroethane (Ethyl chloride) cancer 75-00-3 July 1, 1990 1-(2-Chloroethyl)-3-cyclohexyl- 1-nitrosourea (CCNU) (Lomustine)cancer 13010-47-4 January 1, 1988 1-(2-Chloroethyl)-3-cyclohexyl- 1-nitrosourea (CCNU) (Lomustine)developmental 13010-47-4 July 1, 1990 1-(2-Chloroethyl)-3-(4-methyl- cyclohexyl) -1-nitrosourea (Methyl-CCNU) cancer 13909-09-6 October 1, 1988 Chloroform cancer67-66-3 October 1, 1987 Chloroformdevelopmental 67-66-3 August 7, 2009 Chloromethyl methyl ether (technical grade)cancer 107-30-2 February 27, 1987 3-Chloro-2-methylpropene cancer 563-47-3 July 1, 19891-Chloro-4-nitrobenzenecancer 100-00-5 October 29, 1999 4-Chloro-o -phenylenediamine cancer 95-83-0 January 1, 1988 Chloroprenecancer 126-99-8 June 2, 2000 2-Chloropropionic acid male 598-78-7 August 7, 2009 Chlorothalonilcancer 1897-45-6 January 1, 1989 p -Chloro-o -toluidinecancer 95-69-2 January 1, 1990 p-Chloro-o -toluidine, strong acid salts ofcancer---May 15, 1998 5-Chloro-o -toluidine and its strong acid salts cancer ---October 24, 1997 Chlorotrianisene cancer 569-57-3 September 1, 1996 Chlorozotocin cancer54749-90-5 January 1, 1992 Chlorsulfurondevelopmental, female, male64902-72-3 May 14, 1999 Chromium (hexavalent compounds) cancer--- February 27, 1987 Chromium (hexavalent compounds) developmental female,male--- December 19, 2008 Chrysene cancer 218-01-9 January 1, 1990 C.I. Acid Red 114 cancer 6459-94-5 July 1, 1992 C.I. Basic Red 9 monohydrochloride cancer 569-61-9 July 1, 1989 C.I. Direct Blue 15 cancer 2429-74-5 August 26, 1997 C.I. Direct Blue 218 cancer 28407-37-6 August 26, 1997 C.I. Solvent Yellow 14 cancer 842-07-9 May 15, 1998 Ciclosporin (Cyclosporin A; Cyclosporine) cancer 59865-13-3 79217-60-0 January 1, 1992 Cidofovir cancer, developmental,female, male113852-37-2 January 29, 1999 Cinnamyl anthranilate cancer 87-29-6 July 1, 1989 Cisplatin cancer15663-27-1October 1, 1988Citrus Red No. 2 cancer6358-53-8 October 1, 1989 Cladribine developmental 4291-63-8 September 1, 1996 Clarithromycindevelopmental81103-11-9 May 1, 1997 Clobetasol propionate developmental, female 25122-46-7 May 15, 1998Clofibratecancer637-07-0 September 1, 1996 Clomiphene citratedevelopmental 50-41-9 April 1, 1990 Clorazepate dipotassium developmental 57109-90-7 October 1, 1992 Cobalt metal powder cancer 7440-48-4 July 1, 1992 Cobalt [II] oxide cancer 1307-96-6 July 1, 1992 Cobalt sulfatecancer 10124-43-3 May 20, 2005 Cobalt sulfate heptahydrate cancer10026-24-1 June 2, 2000 Cocainedevelopmental, female 50-36-2 July 1, 1989 Codeine phosphate developmental 52-28-8 May 15, 1998Coke oven emissions cancer---February 27, 1987 Colchicinedevelopmental, male 64-86-8 October 1, 1992 Conjugated estrogens cancer--- February 27, 1987 Conjugated estrogens developmental --- April 1, 1990 Creosotes cancer ---October 1, 1988 p -Cresidine cancer 120-71-8 January 1, 1988 Cumene cancer 98-82-8 April 6, 2010 Cupferron cancer135-20-6 January 1, 1988 Cyanazine developmental 21725-46-2 April 1, 1990 Cycasin cancer14901-08-7 January 1, 1988 Cycloatedevelopmental 1134-23-2 March 19, 1999 Cyclohexanol Delisted January 25, 2002 male108-93-0 November 6, 1998 Cycloheximidedevelopmental 66-81-9 January 1, 1989 Cyclophosphamide (anhydrous) cancer50-18-0 February 27, 1987 Cyclophosphamide (anhydrous) developmental, female, male 50-18-0 January 1, 1989 Cyclophosphamide (hydrated) cancer6055-19-2 February 27, 1987 Cyclophosphamide (hydrated) developmental, female, male6055-19-2 January 1, 1989 Cyhexatin developmental 13121-70-5 January 1, 1989 Cytarabine developmental 147-94-4 January 1, 1989 Cytembena cancer 21739-91-3 May 15, 1998D&C Orange No. 17 cancer 3468-63-1 July 1, 1990 D&C Red No. 8 cancer 2092-56-0 October 1, 1990 D&C Red No. 9 cancer 5160-02-1 July 1, 1990 D&C Red No. 19 cancer 81-88-9 July 1, 1990 Dacarbazine cancer4342-03-4 January 1, 1988 Dacarbazine developmental 4342-03-4 January 29, 1999 Daminozide cancer1596-84-5 January 1, 1990 Danazoldevelopmental 17230-88-5 April 1, 1990 Dantron (Chrysazin; 1,8- Dihydroxy-anthraquinone) cancer117-10-2 January 1, 1992 Daunomycincancer20830-81-3 January 1, 1988 Daunorubicin hydrochloride developmental23541-50-6 July 1, 1990 2,4-D butyric aciddevelopmental , male94-82-6June 18, 1999DDD (Dichlorodiphenyl- dichloroethane) cancer 72-54-8 January 1, 1989 DDE (Dichlorodi-phenyldichloroethylene) cancer 72-55-9 January 1, 1989 DDT (Dichlorodi-phenyltrichloroethane) cancer50-29-3 October 1 , 1987 o,p’-DDT developmental, female, male789-02-6 May 15, 1998 p,p’-DDTdevelopmental, female, male 50-29-3 May 15, 1998 DDVP (Dichlorvos) cancer 62-73-7 January 1, 1989 2,4-DP (dichloroprop)Delisted January 25, 2002 developmental 120-36-5 April 27, 1999 N,N’-Diacetylbenzidine cancer 613-35-4 October 1, 1989 2,4-Diaminoanisolecancer 615-05-4 October 1, 1990 2,4-Diaminoanisole sulfate cancer 39156-41-7 January 1, 1988 4,4’-Diaminodiphenyl ether (4,4’-Oxydianiline) cancer 101-80-4 January 1, 1988 2,4-Diaminotoluenecancer95-80-7 January 1, 1988 Demeclocycline hydrochloride (internal use)developmental 64-73-3 January 1, 1992 Diaminotoluene (mixed) cancer---January 1, 1990 Diazepamdevelopmental 439-14-5 January 1, 1992 Diazoaminobenzene cancer136-35-6 May 20, 2005Diazoxidedevelopmental 364-98-7 February 27, 2001 Dibenz[a,h]acridine cancer 226-36-8 January 1, 1988 Dibenz[a,j]acridine cancer 224-42-0 January 1, 1988 Dibenz[a,h]anthracene cancer 53-70-3 January 1, 1988 7H-Dibenzo[c,g]carbazole cancer 194-59-2 January 1, 1988 Dibenzo[a,e]pyrene cancer 192-65-4 January 1, 1988 Dibenzo[a,h]pyrene cancer 189-64-0 January 1, 1988 Dibenzo[a,i]pyrene cancer 189-55-9 January 1, 1988 Dibenzo[a,l]pyrene cancer 191-30-0 January 1, 1988 Dibromoacetic acidcancer 631-64-1 June 17, 2008 1,2-Dibromo-3-chloropropane (DBCP)cancer 96-12-8 July 1, 1987 1,2-Dibromo-3-chloropropane (DBCP)male 96-12-8 February 27, 1987 2,3-Dibromo-1-propanol cancer 96-13-9 October 1, 1994 Dichloroacetic acid cancer 79-43-6 May 1, 1996 Dichloroacetic acid male 79-43-6 August 7, 2009 p -Dichlorobenzene cancer 106-46-7 January 1, 1989 3,3’-Dichlorobenzidine cancer 91-94-1 October 1, 1987 3,3’-Dichlorobenzidine dihydrochloridecancer 612-83-9 May 15, 1998 1,1-Dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) developmental male 72-55-9 March 30, 2010 1,4-Dichloro-2-butenecancer 764-41-0 January 1, 1990 3,3’-Dichloro-4,4’-diaminodiphenyl ethercancer 28434-86-8 January 1, 1988 1,1-Dichloroethanecancer75-34-3January 1, 1990Dichloromethane (Methylene chloride) cancer75-09-2 April 1, 1988 Dichlorophene developmental 97-23-4 April 27, 1999 Dichlorphenamide developmental 120-97-8 February 27, 2001 Diclofop-methyl cancer51338-27-3 April 6, 2010 Diclofop methyldevelopmental 51338-27-3 March 5, 1999 1,2-Dichloropropane cancer 78-87-5 January 1, 1990 1,3-Dichloropropene cancer542-75-6 January 1, 1989 Dicumarol developmental 66-76-2 October 1, 1992 Dieldrin cancer 60-57-1 July 1, 1988 Dienestrolcancer 84-17-3 January 1, 1990 Diepoxybutanecancer 1464-53-5 January 1, 1988 Diesel engine exhaustcancer ---October 1, 1990 Di(2-ethylhexyl)phthalate (DEHP) cancer117-81-7 January 1, 1988 Di(2-ethylhexyl)phthalate (DEHP) developmental, male 117-81-7 October 24, 2003 1,2-Diethylhydrazine cancer 1615-80-1 January 1, 1988 Diethylstilbestrol (DES) cancer56-53-1 February 27, 1987 Diethylstilbestrol (DES) developmental 56-53-1 July 1, 1987 Diethyl sulfate cancer64-67-5 January 1, 1988 Diflunisaldevelopmental, female 22494-42-4 January 29, 1999 Diglycidyl ethermale 2238-07-5 August 7, 2009 Diglycidyl resorcinol ether (DGRE) cancer101-90-6 July 1, 1989 Dihydroergotamine mesylate developmental 6190-39-2 May 1, 1997 Dihydrosafrolecancer94-58-6 January 1, 1988 Di-n -butyl phthalate (DBP) developmental, female, male84-74-2 December 2, 2005 Di-n -hexyl phthalate (DnHP) female, male 84-75-3 December 2, 2005 Di-isodecyl phthalate (DIDP) developmental 68515-49-1/ 26761-40-0 April 20, 2007 Diisopropyl sulfatecancer2973-10-6 April 1, 1993Diltiazem hydrochloride developmental 33286-22-5 February 27, 2001 3,3’-Dimethoxybenzidine (o -Dianisidine)cancer 119-90-4 January 1, 1988 3,3’-Dimethoxybenzidine dihydrochloride(o -Dianisidine dihydrochloride) cancer 20325-40-0 October 1, 1990 3,3’-Dimethoxybenzidine-based dyes metabolized to 3,3’-dimethoxybenzidinecancer --- June 11, 2004 N, N-Dimethylacetamidedevelopmental 127-19-5 May 21, 2010 4-Dimethylaminoazobenzene cancer 60-11-7 January 1, 1988 trans -2-[(Dimethylamino)methyl- imino]-5-[2-(5-nitro-2-furyl)vinyl]- 1,3,4-oxadiazolecancer 55738-54-0 January 1, 1988 7,12-Dimethylbenz(a)anthracene cancer 57-97-6 January 1, 1990 3,3’-Dimethylbenzidine (ortho-Tolidine)cancer 119-93-7 January 1, 1988 3,3’-Dimethylbenzidine-based dyes metabolized to 3,3’- dimethylbenzidine cancer---June 11, 20043,3’-Dimethylbenzidine dihydrochloridecancer 612-82-8 April 1, 1992Dimethylcarbamoyl chloride cancer 79-44-7 January 1, 1988 1,1-Dimethylhydrazine (UDMH) cancer 57-14-7 October 1, 1989 1,2-Dimethylhydrazine cancer 540-73-8 January 1, 1988 Dimethyl sulfatecancer 77-78-1 January 1, 1988 Dimethylvinylchloride cancer 513-37-1 July 1, 1989 m -Dinitrobenzene male 99-65-0 July 1, 1990 o -Dinitrobenzene male 528-29-0 July 1, 1990 p -Dinitrobenzenemale 100-25-4 July 1, 1990 3,7-Dinitrofluoranthene cancer 105735-71-5 August 26, 1997 3,9-Dinitrofluoranthene cancer 22506-53-2 August 26, 1997 1,6-Dinitropyrene cancer 42397-64-8 October 1, 1990 1,8-Dinitropyrenecancer42397-65-9 October 1, 1990 Dinitrotoluene (technical grade) female, male --- August 20, 1999 Dinitrotoluene mixture, 2,4-/2,6- cancer ---May 1, 1996 2,4-Dinitrotoluene cancer 121-14-2 July 1, 1988 2,4-Dinitrotoluene male 121-14-2 August 20, 1999 2,6-Dinitrotoluene cancer 606-20-2 July 1, 1995 2,6-Dinitrotoluene male606-20-2 August 20, 1999 Dinocap developmental39300-45-3 April 1, 1990 Dinoseb developmental, male 88-85-7 January 1, 1989 1,4-Dioxanecancer 123-91-1 January 1, 1988 Diphenylhydantoin (Phenytoin) cancer57-41-0 January 1, 1988 Diphenylhydantoin (Phenytoin) developmental 57-41-0 July 1, 1987 Diphenylhydantoin (Phenytoin), sodium saltcancer 630-93-3 January 1, 1988 Di-n -propyl isocinchomeronate (MGK Repellent 326)cancer 136-45-8 May 1, 1996 Direct Black 38 (technical grade) cancer 1937-37-7 January 1, 1988 Direct Blue 6 (technical grade) cancer 2602-46-2 January 1, 1988 Direct Brown 95 (technical grade) cancer16071-86-6 October 1, 1988 Disodium cyanodithioimido- carbonate developmental 138-93-2 March 30, 1999 Disperse Blue 1 cancer 2475-45-8 October 1, 1990 Diuroncancer 330-54-1 May 31, 2002 Doxorubicin hydrochloride (Adriamycin)cancer25316-40-9 July 1, 1987 Doxorubicin hydrochloride (Adriamycin)developmental, male 25316-40-9 January 29, 1999 Doxycycline (internal use)developmental 564-25-0 July 1, 1990 Doxycycline calcium (internal use) developmental 94088-85-4 January 1, 1992 Doxycycline hyclate (internal use) developmental 24390-14-5 October 1, 1991 Doxycycline monohydrate (internal use) developmental 17086-28-1 October 1, 1991Endrindevelopmental 72-20-8 May 15, 1998 Environmental tobacco smoke (ETS)developmental ---June 9, 2006 Epichlorohydrin cancer 106-89-8 October 1, 1987 Epichlorohydrin male106-89-8 September 1, 1996 Ergotamine tartrate developmental 379-79-3 April 1, 1990 Erionitecancer12510-42-8/ 66733-21-9October 1, 1988Estradiol 17B cancer 50-28-2 January 1, 1988 Estragolecancer 140-67-0 October 29, 1999 Estrogens, steroidal cancer ---August 19, 2005 Estrone cancer53-16-7 January 1, 1988 Estropipate cancer, developmental 7280-37-7 August 26, 1997 Ethinylestradiol cancer57-63-6 January 1, 1988 Ethionamide developmental 536-33-4 August 26, 1997 Ethoprop cancer 13194-48-4 February 27, 2001 Ethyl acrylatecancer140-88-5 July 1, 1989 Ethyl alcohol in alcoholic beverages developmental ---October 1, 1987 Ethylbenzenecancer 100-41-4 June 11, 2004Ethyl-tert-butyl ethermale637-92-3 December 18, 2009 Ethyl dipropylthiocarbamate developmental 759-94-4 April 27, 1999 Ethyl-4,4’-dichlorobenzilate cancer 510-15-6 January 1, 1990 Ethylene dibromide cancer106-93-4 July 1, 1987 Ethylene dibromide developmental, male 106-93-4 May 15, 1998 Ethylene dichloride (1,2-Dichloroethane)cancer107-06-2 October 1, 1987 Ethylene glycol monoethyl ether developmental, male 110-80-5 January 1, 1989 Ethylene glycol monoethyl ether acetatedevelopmental, male 111-15-9 January 1, 1993 Ethylene glycol monomethyl ether developmental, male 109-86-4 January 1, 1989 Ethylene glycol monomethyl ether acetate developmental, male 110-49-6 January 1, 1993 Ethyleneimine cancer 151-56-4 January 1, 1988 Ethylene oxide cancer 75-21-8 July 1, 1987Ethylene oxide female75-21-8 February 27, 1987 Ethylene oxide developmental, male 75-21-8 August 7, 2009 Ethylene thiourea cancer96-45-7 January 1, 1988 Ethylene thiourea developmental 96-45-7 January 1, 1993 2-Ethylhexanoic acid developmental 149-57-5 August 7, 2009 Ethyl methanesulfonate cancer62-50-0 January 1, 1988 Etodolac developmental, female 41340-25-4 August 20, 1999 Etoposide developmental 33419-42-0 July 1, 1990 Etretinate developmental 54350-48-0 July 1, 1987Fenoxaprop ethyl developmental 66441-23-4 March 26, 1999 Fenoxycarb cancer72490-01-8 June 2, 2000Filgrastimdevelopmental 121181-53-1 February 27, 2001 Fluazifop butyl developmental69806-50-4 November 6, 1998 Flunisolide developmental, female 3385-03-3 May 15, 1998 Fluorouracildevelopmental 51-21-8 January 1, 1989 Fluoxymesteronedevelopmental 76-43-7 April 1, 1990 Flurazepam hydrochloride developmental1172-18-5 October 1, 1992 Flurbiprofen developmental, female 5104-49-4 August 20, 1999 Flutamidedevelopmental 13311-84-7 July 1, 1990 Fluticasone propionate developmental 80474-14-2 May 15, 1998Fluvalinate developmental 69409-94-5 November 6, 1998 Folpetcancer 133-07-3 January 1, 1989 Formaldehyde (gas)cancer 50-00-0 January 1, 1988 2-(2-Formylhydrazino)-4- (5-nitro-2-furyl)thiazolecancer3570-75-0January 1, 1988Fumonisin B 1 cancer 116355-83-0 November 14, 2003 Furancancer 110-00-9 October 1, 1993 Furazolidone cancer 67-45-8 January 1, 1990 Furmecyclox cancer 60568-05-0 January 1, 1990 Fusarin C cancer 79748-81-5 July 1, 1995Gallium arsenide cancer1303-00-0 August 1, 2008 Ganciclovircancer, developmental, male82410-32-0 August 26, 1997 Ganciclovir sodiumdevelopmental, male 107910-75-8 August 26, 1997 Gasoline engine exhaust (condensates/extracts) cancer ---October 1, 1990 Gemfibrozil cancer25812-30-0 December 22, 2000 Gemfibrozilfemale, male 25812-30-0 August 20, 1999 Glasswool fibers (airborne particles of respirable size)cancer ---July 1, 1990 Glu-P-1 (2-Amino-6-methyldipyrido [1,2- a:3’,2’-d]imidazole) cancer 67730-11-4 January 1, 1990 Glu-P-2 (2-Aminodipyrido [1,2-a:3’,2’-d]imidazole) cancer67730-10-3 January 1, 1990 Glycidaldehyde cancer 765-34-4 January 1, 1988 Glycidolcancer556-52-5 July 1, 1990 Goserelin acetatedevelopmental, female, male 65807-02-5 August 26, 1997 Griseofulvincancer 126-07-8 January 1, 1990 Gyromitrin (Acetaldehyde methylformylhydrazone) cancer16568-02-8 January 1, 1988Halazepamdevelopmental 23092-17-3 July 1, 1990 Halobetasol propionate developmental66852-54-8 August 20, 1999 Haloperidol developmental, female 52-86-8 January 29, 1999 Halothane developmental 151-67-7 September 1, 1996 HC Blue 1 cancer 2784-94-3 July 1, 1989 Heptachlor cancer76-44-8 July 1, 1988 Heptachlordevelopmental 76-44-8 August 20, 1999 Heptachlor epoxidecancer 1024-57-3 July 1, 1988 Herbal remedies containing plant species of the genus Aristolochia cancer --- July 9, 2004 Hexachlorobenzene cancer118-74-1 October 1, 1987 Hexachlorobenzene developmental 118-74-1 January 1, 1989 Hexachlorocyclohexane (technical grade)cancer ---October 1, 1987 Hexachlorodibenzodioxin cancer 34465-46-8 April 1, 1988 Hexachloroethanecancer 67-72-1 July 1, 1990 2,4-Hexadienal (89% trans, trans isomer; 11% cis, trans isomer) cancer --- March 4, 2005 Hexafluoroacetonemale 684-16-2 August 1, 2008 Hexamethylphosphoramide cancer 680-31-9 January 1, 1988 Hexamethylphosphoramide male680-31-9 October 1, 1994 Histrelin acetatedevelopmental---May 15, 1998Hydramethylnon developmental, male 67485-29-4 March 5, 1999 Hydrazinecancer 302-01-2 January 1, 1988 Hydrazine sulfatecancer 10034-93-2 January 1, 1988 Hydrazobenzene (1,2- Diphenylhydrazine) cancer122-66-7 January 1, 1988 1-Hydroxyanthraquinone cancer129-43-1 May 27, 2005 Hydroxyurea developmental 127-07-1 May 1, 1997Idarubicin hydrochloride developmental, male 57852-57-0 August 20, 1999 Ifosfamide developmental 3778-73-2 July 1, 1990 Iodine-131developmental 10043-66-0 January 1, 1989 Indeno[1,2,3-cd]pyrene cancer 193-39-5 January 1, 1988 Indium phosphidecancer 22398-80-7 February 27, 2001 IQ (2-Amino-3-methylimidazo [4,5-f] quinoline) cancer 76180-96-6 April 1, 1990 Iprodione cancer 36734-19-7 May 1, 1996 Iprovalicarbcancer 140923-17-7 140923-25-7 June 1, 2007 Iron dextran complex cancer 9004-66-4 January 1, 1988 Isobutyl nitrite cancer 542-56-3 May 1, 1996 Isoprenecancer 78-79-5 May 1, 1996 Isosafrole Delisted December 8, 2006 cancer120-58-1 October 1, 1989 Isotretinoin developmental 4759-48-2 July 1, 1987Isoxaflutole cancer 141112-29-0 December 22, 2000Lactofen cancer 77501-63-4 January 1, 1989 Lasiocarpine cancer303-34-4 April 1, 1988Leaddevelopmental, female, male ---February 27, 1987 Lead and lead compounds cancer ---October 1, 1992 Lead acetate cancer 301-04-2 January 1, 1988 Lead phosphate cancer 7446-27-7 April 1, 1988 Lead subacetate cancer1335-32-6 October 1, 1989 Leuprolide acetatedevelopmental, female, male74381-53-6 August 26, 1997 Levodopadevelopmental 59-92-7 January 29, 1999 Levonorgestrel implantsfemale 797-63-7 May 15, 1998 Lindane and other hexachloro- cyclohexane isomers cancer ---October 1, 1989 Linurondevelopmental 330-55-2 March 19, 1999 Lithium carbonate developmental 554-13-2 January 1, 1991 Lithium citrate developmental 919-16-4 January 1, 1991 Lorazepam developmental 846-49-1 July 1, 1990 Lovastatin developmental 75330-75-5 October 1, 1992 Lynestrenol cancer 52-76-6 February 27, 2001Mancozeb cancer 8018-01-7 January 1, 1990 Manebcancer 12427-38-2 January 1, 1990 Marijuana smokecancer---June 19, 2009。