中国药科大学中药学专业英语课件-甘草

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Since ancient times in China, it has been called the National Venerable Master (国老) because it has the merit of harmonizing and mollifying drugs in a prescription and eliminating various toxicities.


Radix Glycyrrhizae
[English Name] Liquorice Root
Origins

Gancao is one of the most commonly used Chinese herbs, and classified as a superior herb in Shen Nong Ben Cao Jing. The Chinese name Gancao means the sweet herb, hence its name.

Plant Morphology
Glycyrrhiza uralensis: 甘草
A perennial herb , 30~100 cm high, covered with white pubescences, glandular scars or glandular hairs throughout. Rhizome cylindrical ; main root relatively long, stout, outer bark reddish-brown to dark brown, taste sweet.
甘草粉末
粉末: (1)晶纤维细长,壁极厚,
微木化;含晶细胞壁增厚;
(2)木栓细胞棕红色,壁薄,
微木化。
Chemical Constituents
Triterpenoidal saponins: 6~14%
glycyrrhizin ( 甘 草 甜 素 ) , which upon hydrolysis yields glucuronic acid (葡萄糖醛酸)and glycyrrhetinic acid(甘草
branchlet 羽状的 托叶
总状花序

花萼
花冠
Flowers in axillary racemes, dense; calyx campanulate, 5-lobed; corolla papilion-aceous (butterfly-like), purplish-red or bluish-purple; stamens 10, diadelphous; ovary sessile, tapering upwards to become a style.
Legume:荚果 prickly: 多刺的 calcareous glasslands:钙质草原

Plant Morphology

Glycyrrhiza inflate Bat. : Plant without glandular hairs; leaflets 3-7; Legume small, inflated. Distributed in Xinjiang and Gansu. Glycyrrhiza glabra L.: Plant without glandular hairs; leaflets 19; Legume flat and straight, glabrous. Distributed in Xinjiang, Qinghai and Gansu.
(3)形成层环不甚明显;
(4)木质部导管直径大,单个或2~3个成 束; (5)韧皮部和木质部均有晶纤维; (6)薄壁细胞含淀粉粒。
Microscopical characters

Powder:
Biblioteka Baidu
Brownish-yellow. Fibres in bundles, 8~14μm in diameter,
木化纤维

Radix Glyvyrrhizae Glabrae: Texture of root and
rhizomes relatively compact, some branched, the outer bark not rough, greyish-brown, lenticels small and indistinct.
furrows:沟纹 sparse:稀疏的
Description
纤维性 的

Texture compact, fracture fibrous, yellowishwhite, starchy, cambium ring distinct, rays radiate, some with clefts. Rhizomes cylindrical, externally with bud scars, pith present in the centre of fracture. Odour, slight; taste, sweet and characteristic.
ventilated: 通风的 bales:大包,捆
Description

Radix Glycyrrhiza Uralensis: Roots cylindrical. 2~100 cm long, 0.6~3.5 cm in diameter. Externally reddishbrown or grayish-brown, showing irregular longitudinal wrinkles and furrows, numerous transverse lenticellike protrusions and sparse rootlet scars. Sometimes the outer bark scaling off, the exposed surface appearing yellow.
次酸)
Flavonoids:
liquritin (甘草苷) , liquiritigenin( 甘草苷元) (the aglycone of liquiritin) ( 甘 草 苷 的 苷 元 ) , isoliquiritin ( 异 甘 草 苷 ) , isoliquiritigenin(异甘草苷元)。
thick-walls,slightly lignified, surrounded by parenchymatous cells containing prisms of calcium oxalate, forming crystal fibres. Prisms of calcium oxalate frequent. Bordered pitted vessels large, reticulated vessels rare. Cork cells reddish-brown, polygonal, slightly lignified.
parenchymatous cells containing prisms of calcium oxalate. Roots
without pith at the centre; rhizomes possessing pith at the centre.
【显微特征】
横切面: (1)木栓层细胞红棕色; (2)韧皮部由韧皮纤维束、韧皮薄壁细胞 及筛管群等间隔排列;

Collection and Preparation
The drug is collected in spring and autumn, removed from stems and rootlets, cut into sections (about 1m long), sunned to be 60~70% dried, the roots and the rhizomes being bundled into bales, and then preserved in a ventilated dry place until dried completely. Some of liquorice roots are deprived of the cork. It is called starchy liquorice(粉甘草).
cleft:裂隙; bud scars:芽痕 ;
pith:髓
Description

Radix Glycyrrhizae Inflatae: Roots and rhizomes
woody and stout, some branched, the outer bark rough, greyish-brown, Texture compact, more lignified fibres and less starchy, Rhizomes with more and large advantitious buds.
pubescences: 软毛,绒毛, 到达青春期; glandular : 腺体的
Plant Morphology

Stem erect, branchelets with ridges. Leaves pinnately compound, alternate, leaflets 7 ~ 17, ovate or broadly ovate, entire; stipules deciduous.
三萜皂甙类化合物
COOH H O
HO
18-甘草次酸
雄蕊
Plant Morphology

Legume (pod) curved to be sickle-like, densely covered with brown prickly glandular hairs. Seeds 2~8, black, smooth. Flowering season Jun.~Jul. ; fruiting season Jul.~Aug.. It is usually grown wild in sunny calcareous grasslands and along the sandy riverbanks, and now also cultivated. Distributed in Northeast China, North China and Northwest China.
Microscopical characters

Transverse section:
phelloder m
Cork consisting of several layers of brown cells. Cortex relatively narrow. Phloem rays broad, mostly curved, frequently with clefts; most phloem fibres in bundles, unlignified or slightly lignified, surrounded by parenchymatous cells containing prisms of calcium oxalate; sieve tube tissue often pressed to be collapsed. Fascicular cambium distinct. Xylem rays 3~5 cells wide; vessels frequent up to 160 μm in diameter; xylem fibres in boundless, surrounded by
It is the dried root and rhizome of Glycyrrhiza uralensis Fisch. , Glycyrrhiza inflate Bat. Or Glycyrrhiza glabra L. , family Leguminosae.
harmonize:调和 mollify:缓和
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