隐匿性脑梗死和多血管床病变相关性研究

隐匿性脑梗死和多血管床病变相关性研究

［摘要］目的研究隐匿性脑梗死（SCO和多血管床病变

（PolyVD）的相关性，为识别脑梗死高危人群提供依据。方

法纳入2015年2月〜2016年6月入住台州市中心医院神经内科的患者，95 例被确诊为首次隐匿性脑梗死的患者作为脑梗死组，95 例同期头晕、头痛而经头颅MRI 证实无梗死灶者作为对照组。检测外周动脉区（颈动脉、锁骨下动脉、下肢动脉）及冠状动脉、颅内动脉，比较各个区域血管床病变情况。结果两组患者在性别、年龄、烟酒史及高血压病史、糖尿病史、冠心病史、血脂基线水平等方面差异无统计学意义

（P>0.05）。检测外周血管区（颈动脉、锁骨下动脉、下肢动

脉）及冠状动脉、颅内动脉，相应动脉病变检出率，脑梗死组分别为65.3%、24.2%、33.7%，21.1%、32.6%，对照组分

别为49.5%、17.9%、25.3%、15.8%、24.2%，其中脑梗死组颈动脉斑块检出率高于对照组，差异有统计学意义（

2=4.842，P=0.028）两组病变血管检出条数率分别为35.4%、27.4%,脑梗死组咼于对照组，差异有统计学差异（X 2=8.689,

P=0.003）。外周动脉、冠状动脉、颅内动脉的三个区域，两

组1 个区域发生动脉粥样硬化病变分别是37.9%、72.6%，存

在2个区域血管病变分别为47.4%、22.1%，存在3个区域血

管病变分别为14.7%、5.3%，两组病变区域比较，差异有统

计学意义（Z=4.761，P=0.000

[关键词] 脑梗死；多血管床；外周动脉；冠状动脉

[中图分类号] R743.3；R766 [文献标识码] A [文章编号] 1673-9701（2016）33-0008-04

[Abstract] Objective To study the correlation

between

silent cerebral infarction （SCI）and polyvascular disease

PolyVD），and to provide evidence for identifying high risk population of cerebral infarction. Methods From February 2015 to June 2016，patients admitted to Department of Neurology ，

the Central Hospital of Taizhou City were enrolled in

this study.

Among them ，95 patients who were diagnosed as first SCI were enrolled in the cerebral infarction group ，95 patients with dizziness and headache while had no cerebral infarction confirmed by head MRI were enrolled in the control group.

Peripheral arterial areas （carotid artery ，subclavian artery ，

lower extremity artery ），coronary artery and intracranial artery were examined ，the vascular bed lesions were compared in each region. Results There were no significant differences in sex ，age，history of alcohol and tobacco ，

hypertension ，diabetes mellitus ，coronary heart disease and blood lipid baseline level between the two

groups （P>0.05）.

The detection rate of cerebral arteries was 65.3% ，

24.2%，

33.7%，21.1% and 32.6% respectively in the peripheral arterial areas (carotid artery ，subclavian artery，lower extremity artery )，coronary artery and

intracranial artery ，while the

control group was 49.5% ，17.9%，25.3%，

15.8%，24.2% respectively ，

in which，the carotid plaque detected was significantly higher in the cerebral infarction group than that in the control group ，the difference was statistically significant

x 2=4.842，P=0.028) . The ratio of the number of

blood vessels detected in the two groups were 35.4% and 27.4% ，

respectively ，which was higher in the cerebral infarction group than the control group ，the difference between the two groups was statistically significant ( x 2=8.689, P=0.003) . The incidence of one atherosclerotic lesion occured in the three regions of peripheral

artery ，coronary artery and intracranial artery between the two groups was 37.9% and 72.6% ，while the incidence of two lesions occurred was 47.4% and 22.1% ，

respectively ，the incidence of three lesions occurred was 14.7%

and 5.3%，respectively ，showed statistically

significant

differences between the two groups ( Z=4.761，P=0.000 [Key words] Cerebral infarction ；Polyvascular；