上海交通大学九院临床学院Ninth-Hospitol-Medical-School-of-...
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•>140对与癫痫相关基因 •家族史
6
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继发性/症状性
Symptomatic/Secondary
肿 瘤 Tumour 外伤 Injure *脑血管病 Cerebrovasculair diseases
高热惊厥
convulsion caused by Intense fever
toxicosis
The Commission on Classification and Terminology of the International League Against Epilepsy in 1981
A.Debut from ? Partialness
B.Without loss of consciousness or alteration in psychic function ? Simple seizurs
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癫痫和癫痫综合征分类 和临床表现
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13ຫໍສະໝຸດ Baidu
发作类型Type of seizure
l l l l l 单发性型 (Isolated) 周期性型 (Cyclic) 延迟型(Prolonged) 反复发作型(Repetitive) 癫痫的持续状态 (Status epilepticus)
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病 因 (Etiology)
•先天性 •症状性 •隐源性 Idiopathic;Primary Symptomatic;Secondary Cryptogenetic
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5
先天性因素
Idiopathic / Primary
遗传异常 Epileptogene
Generation
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和部位有关的癫痫(局灶性发作)
The Characteristic of Partial Seizure
•单纯局限于病灶部位有关的体征 •发作的临床表现和病灶部位有关 •可以伴有或不伴有意识障碍 •Jackson’s 抽搐
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The Classification of Seizures)
中 毒
先天畸形
营养、代谢 疾病
Nutrition and metabolize disorder
变 性 Denaturalization
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感染 Infection
7
影响癫痫发作的因素
The effective factor to seizure
*遗传因素Genetic factor *年龄 Age *内分泌 Incretion *睡眠 Sleeping *诱发因素 Predisposing Cause
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3
痫性发作 Seizure
一次中枢神经系 统功能失常发作的临 床过程。
-- The act or result of a sudden attack of an illness, character as a sudden attack, spasm, or convulsion, as in epilepsy or another disorder.
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The Classification of Seizures)
The Commission on Classification and Terminology of the International League Against Epilepsy in 1981
A.Debut from ? Partialness
癫痫和癫痫综合征 Epilepsy and seize syndrom
上海交通大学九院临床学院
Ninth Hospitol Medical School of SJTU
神经病学教研组
Dpartment of Neurology
李
威
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1
is a term used to describe sudden recurrent transient disturbances in mental function and movements of the body or both which result from excessive discharging of populations of brain cells.
--- Eli S.Goldensohn et al: Scientific Approaches to Clinical Neurology. 1977
Epilepsy
The discharge may result in an almost instantaneous loss of consciousness, alteration of perception or impairment of psychic function, convulsive movements, disturbance of sensation, or some combination thereof.
A. Debut from ? Partialness
B.Without loss of consciousness or alteration in psychic function ? Simple seizures
Generation
Yes
Complex seizures
No
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17
The Classification of Seizures)
The Commission on Classification and Terminology of the International League Against Epilepsy in 1981
hhhhhhhhhhh 2 2001 Maurice Victor, Allan H.Ropper et al: Adams and Victor's Principles of Neurology. 7th edition,
Epilepsy
以大脑半球神经元反复 发作性异常放电导致中枢神 经系统暂时性功能失常的慢 性疾病。