【管理资料】浅谈骨转移性乳腺癌汇编

Laboratory examination
• 2011-02-09 1.Hepatic functions – ALT 40 U/L – AST 20 U/L – TB Normal 3.Tumor markers – CA19-9 Normal
• 2. Blood routine test
Hb 82 g/L RBC 4.54×1012 /L WBC 6.1×109 /L
Primary diagnosis
Breast cancer with bone metastasis
Treatment
On February 11, 2011
in orthopedic department,
The Patient received
"the seventh thoracic tumor resection and pedicle screw fixation"
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Thoracic MRI examination
Thoracic MRI examination
Enhanced MRI
High-density mass was shown on the seventh thoracic, and bone destruction also had been found.
• NLeabharlann Baidu hepatitis, hypertension, or diabetes
• No smoking, alcohol or drug abuse
• No inherited diseases • No history of drug allergy • Normal menstruation
Immunohistochemical
ER++ PR++ CerbB2E-cad+++,Ki6750%+,P53+,Ck5/6-
Treatment
• After operation, the patient continued to receive chemotherapy and radiotherapy.
Histological examination
Seventh thoracic tumors was identified as metastatic carcinoma, and the immunohistochemistry results showed the possibility of breast cancer bone metastasis was very large
• PLT 201 ×109 / L
puncture biopsy
• She received ultrasound guided breast core needle puncture biopsy
• Puncture tissue pathology :The left breast invasive ductal carcinoma
• The pain was tingling, especially in night-time
• The patient took orally traditional Chinese medicine , but had not tangible effects
Past, Personal & Family History
浅谈骨转移性乳腺癌
Chief complaint
• She got hypoesthesia of lower limbs and inability to walk for more than a month
History of present illness
• The patient felt pain on the back by no obvious incentives in June 2010
Chemotherapy two times before operation: February 23 ,2011 March 20 ,2011
The chemotherapy plan was TEC
Treatment
After the chemotherapy
The lesions area of left breast showed no reduction
IMMUNOHISTOCHEMICAL results
ER++ PR++ CerbB2- CK20EMA++,Ckpan+++,CK5/6-
Treatment
The patient recovered well , and then transferred into our department
Clinical findings
The left breast presented with diffused erythema and edema , induration about size of 3.0cm*3.0cm
Ultrasound examination
a 3 cm left breast mass and a normal right breast
Treatment
Modified radical mastectomy on march
31,2011
Bilateral oophorectomy
On the same day
Histological examination
The left breast invasive ductal carcinoma The basal resection margin of tumor was close to the surrounding normal tissue The axillary lymph nodes metastasis (13/15)